Alliance for Cellular Signaling
The Signaling Gateway was initially created through a collaboration between Nature Publishing Group and the Alliance for Cell Signaling (AfCS). The overall goal of the Alliance for Cellular Signaling was to understand as completely as possible the relationships between sets of inputs and outputs in signaling cells that vary both temporally and spatially. The same goal, stated from a slightly different perspective, was to understand fully how cells interpret signals in a context-dependent manner. This work involved the identification of many of the proteins that comprise the various signaling systems, the assessment of time-dependent information flow through the systems in both normal and pathological states, and finally the reduction of the mass of detailed data into a set of interacting theoretical models that describe cellular signaling. All primary research results from experiments previously performed by the Alliance for Cellular Signaling (AfCS), including B-lymphocyte and RAW 264.7 ligand screens and yeast two-hybrid data are archived in the data center.
AfCS Newsletters
- Vol IV, No. 3 Dec, 2004
- Vol IV, No. 2 Jul, 2004
- Vol IV, No. 1 May, 2004
- Vol III, No. 3 Nov, 2003
- Vol III, No. 2 Jul, 2003
- Vol III, No. 1 May, 2003
- Vol II, No. 4 Dec, 2002
- Vol II, No. 3 Dec, 2002
- Vol II, No. 2 Jul, 2002
- Vol II, No. 1 Apr, 2002
- Vol I, No. 4 Nov, 2001
- Vol I, No. 3 Jul, 2001
- Vol I, No. 2 Mar, 2001
- Vol I, No. 1 Dec, 2000
AfCS Annual Meetings