Third Annual Meeting Agenda
(pdf version)
|
| The Alliance for Cellular Signaling |
| Pasadena, CA May 18-21, 2003 |
| Arrival: Sunday, May 18th |
| 7:30 - 9:30PM |
Reception at the Westin Pasadena, 191 North Los Robles, Pasadena, CA. Courtyard/Plaza, Main Level |
| All sessions will be held on the campus of the California
Institute of Technology, Beckman Institute Auditorium |
| |
| Monday, May 19 |
| Shuttles will depart the Westin for Cal Tech every 15-20
minutes between 7 & 7:45 AM. Meet the shuttles at the Main Entrance to the hotel. |
| 7:15-8:00 |
Continental Breakfast, Courtyard/Plaza, Beckman Institute |
|
| 8:00-8:45 |
Introduction |
Al Gilman |
| 8:45-10:15 |
Single ligand screen in B cells |
|
| 8:45-9:00 |
Goals and plans for the ligand screen experiments |
Elliott Ross |
| 9:00-9:20 |
Single ligand screen: What did we do; what did we learn about protocols, ligands, and
cells? Signaling experiments (5 min. for questions) |
Rama Ranganathan |
| 9:25-9:50 |
Single ligand screen: What did we do; what did we learn about protocols, ligands, and cells?
Microarray experiments (5 min. for questions) |
Mel Simon |
| 9:55-10:25 |
Break |
|
| 10:25-12:00 |
Double ligand screen in B cells |
|
| 10:25-10:50 |
Double ligand screen:experimental design and initial patterns of interaction
(5 min. for questions) |
Paul Sternweis |
| 10:55-11:15 |
Analysis and results of double ligand screen data (5 min for questions) |
Rama Ranganathan |
| 11:20-11:50 |
Discussion |
|
| 11:50-12:00 |
What comes next |
Elliott Ross |
| 12:00-1:00 |
Lunch. Courtyard/Plaza, Beckman Institute |
|
| 1:00-2:30 |
Other ongoing measurements. Consider relationship with ligand screen.
How much should be done now; how much should be deferred? Consider use of ligand cocktails rather
than individual treatments. |
|
| 1:00-1:30 |
Phospholipids
and potential interactions with LIPID MAPS project |
Alex Brown |
| 1:30-2:00 |
Protein
location and translocation; domain translocation. Dominant negatives
and constitutively actives now or later? |
Tobias Meyer |
| 2:00-2:30 |
Ligand-stimulated protein phosphorylation. Antibodies and other techniques. Tyr
vrs. Ser/Thr. Target-specific vrs. non-specific. [A] [B] |
Susanne Mumby / Marc Mumby |
| 2:30-3:00 |
Break |
|
| 3:00-4:30 |
Other ongoing measurements (continued):
Protein-protein interactions |
|
| 3:00-3:30 |
Yeast two hybrid |
Iain Fraser |
| 3:30-4:00 |
Protein complementation assays |
Steve Michnick |
| 4:00-4:30 |
Pull-downs |
Paul Sternweis / Marc Mumby |
| 4:30-5:30 |
Breakouts |
|
|
Collaborators with AfCS
Laboratories, Main Auditorium |
|
|
Data analysis
group, 121 Beckman Institute |
|
|
Editorial Board, 115 Beckman Institute |
|
|
External Advisory
Committee, 201 Braun |
|
|
Steering
Committee, 228 Beckman Institute |
|
|
Others:
Free time and poster preparation |
|
| Shuttles between the hotel and the meeting will be available from 4:30 - 6:30 |
| 5:30-7:00 |
Posters and Beer, Courtyard/Plaza, Beckman Institute |
|
| 7:00 |
Dinner, Courtyard/Plaza, Beckman Institute |
|
| Shuttles will run between the campus and hotel from 8:30 - 9:30 PM |
| |
| Tuesday, May 20 |
| Shuttles will
depart the Westin for Cal Tech every 15-20 minutes between 7 & 7:45.
Meet the shuttles at the Main Entrance to the hotel |
| 7:15-8:00 |
Continental
breakfast, Courtyard/Plaza, Beckman Institute |
|
| 8:00-8:20 |
Criteria for choice of an additional cell system |
Ron Taussig |
| 8:20-9:15 |
The Macrophage |
Kelly Smith and general discussion |
| 9:15-10:10 |
AfCS Experimental observations on new candidate cell lines, Pt. 1 |
|
| 9:15-9:30 |
Transfection |
Deirdre Brekken |
| 9:30-9:35 |
Infection |
Tamara Roach |
| 9:35-9:45 |
Microscopy |
Grischa Chandy |
| 9:45-10:10 |
RNAi |
Iain Fraser |
| 10:10-10:40 |
Break |
|
| 10:40-11:30 |
AfCS Experimental observations on new candidate cell lines, Pt. 2 |
|
| 10:40-10:55 |
Transcript analysis |
Sangdun Choi |
| 10:55-11:05 |
cAMP & calcium responses |
Robert Hsueh |
| 11:05-11:10 |
Phosphoproteins |
Heping Han |
| 11:10-11:30 |
Summary, discussion, & questions |
|
| 11:30-12:00 |
Parts List Database |
Mel Simon |
|
Problem of Isoform Specificity |
David Fruman |
|
Parts List, Database, Isoform Detection |
Shankar Subramaniam |
| 12:05-1:30 |
Lunch. Courtyard/Plaza, Beckman Institute |
|
| 1:30-2:20 |
Using databases and extracting pathways from AfCS Data |
Shankar Subramaniam |
| 2:20-2:50 |
I. Extracting pathway information from experimental data and databases |
Bruce Conklin |
| 2:50-3:20 |
Break |
|
| 3:20-3:50 |
II. Extracting pathways |
Adam Arkin |
| 3:50-4:30 |
III. Inferring interactions and pathways from
genomic and microarray data |
David Eisenberg |
| 4:30 |
Breakouts |
|
|
Steering Committee with External Advisory Committee, 115 Beckman Inst. |
|
|
Others: Free time |
|
| Shuttles between the hotel and the
meeting will be available from 4:30 - 6:00 |
| 6:00 |
Reception/Dinner, The Athenaeum, Cal Tech Campus |
|
| Shuttles will run between the
campus and hotel between 4:30 and 6:00 PM and 8:30 and 9:30 PM |
| |
| Wednesday, May 21 |
| Shuttles will depart the Westin
for Cal Tech every 15-20 minutes between 7:45 & 8:30. Meet the shuttles at the Main Entrance to the hotel |
| 8:00-8:30 |
Continental Breakfast |
|
| 8:30-9:30 |
Molecule Page Database Demonstration |
Pat Casey / Ron Taussig |
| 9:30-11:00 |
General Discussion |
|
|
Prioritization/work plan led by Steering Committee |
|
|
FPM plans: Bourne |
|
| Please check in at
registration desk for information regarding transportation to airports. |
