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AfCS Yeast 2-Hybrid Screen
The following interface can be used to list proteins that have
given interactions using the yeast two-hybrid system. A description of
the AfCS Y2H screen can be found at About Y2H.
Archive of latest data release:
14-OCT-05
To browse lists of all bait proteins, all prey proteins, or all
proteins involved in interactions, use the buttons below:
To search for specific proteins, enter a keyword (ex. kinase, Rac,
Rho, phosphatase, etc.) or AfCS ID into the box below to list matching
proteins that have been identified in the screen. Note that the search
is not case sensitive and individual proteins can appear as both bait
and prey.
A further 59 new Y2H interactions were released 2/28/05. They
involve 17 of the baits selected by the AfCS (GRK2, CALM, CAML,
FCER1G, ITK, ITPR1, PIK3CA, PIK3CG, PIP5K2C, PLCD1, PLCE1, PIK3R5,
PPP2R1A, PTEN, RGS19, SOS and NTAL). 56 prey proteins were pulled out
by these baits. Interactions of note were both Grk2 and PI3Kp110a with
the p105 subunit of NFkB, calmodulin with several myosin isoforms and
NOS2, PP2A with protein kinase N and 2 striatin protein family members
and NTAL with a calcium modulating ligand. 53 proteins appeared in the
AfCS data set for the first time in this release.
Summary of incremental results
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