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Molecule Pages: A comprehensive signaling database

The Molecule Pages contain key facts about more than 3900 proteins involved in cellular signaling. For each of these proteins, the database provides a large amount of automated data that provide genetic and structural information, biophysical properties, and so on.

These data are being supplemented with reviews of the functions, interactions and regulation of each protein. These reviews are commissioned by NPG editorial staff, written by experts in the field, peer reviewed, and are citable using digital object identifiers (DOIs).

The Molecule Pages allow users to explore how proteins interact in complexes or in pathways, with references to the supporting literature. As we add new reviews, the Molecule Pages database is evolving into a model of an artificial cell representing all signaling molecules and their binding partners.

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10 MOST RECENTLY PUBLISHED: expert-authored, peer-reviewed information on

• C5a receptor
• S6K1
• S6K2
• Phosphatidylinositol 4-kinase type II alpha
• Gab1
• Rcan1-4
• AP-3 beta3a
• AP-3 delta
• Pink1
• GABA A receptor alpha 6 subunit

View all published Molecule Pages

10 MOST POPULAR PAGES (June 2008):

1. Calcium-sensing receptor
2. Catenin, beta
3. Pink1
4. GABA A receptor alpha 6 subunit
5. Gab1
6. Rac2
7. Luteinizing hormone receptor
8. Vav2
9. Rab8a
10. Wee1

MOLECULE PAGE STATISTICS

MOLECULE PAGES FOCUSING ON:

EXPORTED DATA

Tab-delimited files relating the Molecule Pages to protein accession and NCBI Gene ID are availabe for ftp download at ftp://ftp.afcs.org/pub/mpdata/. We also provide text files with name, synonym, and sequence information.