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Molecule Pages: A comprehensive signaling database

The UCSD-Nature Signaling Gateway Molecule Pages provide essential information on over 4000 proteins involved in cellular signaling. Each Molecule Page contains regularly updated information derived from public data sources as well as sequence analysis, references and links to other databases. Published Molecule Pages contain an expert-authored review article that describes the biological activity, regulation and localization of the protein. This review is supplemented by highly structured data that illustrate protein-protein interactions, post-translational modifications, subcellular localization and biological function.

Prior to publication, Nature Publishing Group administers rigorous peer and editorial review of each Molecule Page. The published pages are citable by digital object identifiers (DOIs). All data in the Molecule Pages are freely available to the public.

RSS feed now includes the Molecule Pages

The Signaling Update RSS feed now encompasses the Molecule Pages database. Information on newly published Molecule Pages, as well as updates and improvements to the database, is posted to the RSS feed each Friday.

Getting started guide

Our getting started guide is available for download as a PDF. The guide provides a quick overview of the anatomy of a published Molecule Page, and highlights the wealth of data that are available for all the Molecule Pages in the database.

10 MOST RECENTLY PUBLISHED: expert-authored, peer-reviewed information on

• p38 gamma MAP kinase
• WASH
• ASK1
• Chemokine ligand CX3CL1
• Rgs8
• Phosphodiesterase 4D, cAMP specific
• Hpk1
• ATF2
• SerpinB2
• Msk1

View all published Molecule Pages

10 MOST POPULAR PAGES (August 2010):

1. ASK1
2. Rgs8
3. Phospholipase C delta4
4. Chemokine ligand CX3CL1
5. mTOR
6. WASH
7. Catenin, beta
8. Integrin alpha V
9. Protein kinase C delta
10. Prion protein

MOLECULE PAGE STATISTICS

MOLECULE PAGES FOCUSING ON:

EXPORTED DATA

Tab-delimited files relating the Molecule Pages to protein accession and NCBI Gene ID are availabe for ftp download at ftp://ftp.afcs.org/pub/mpdata/. We also provide text files with name, synonym, and sequence information.