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Molecule Pages: A comprehensive signaling database

The UCSD-Nature Signaling Gateway Molecule Pages provide essential information on more than 3900 proteins involved in cellular signaling. Each Molecule Page contains regularly updated information derived from public data sources as well as sequence analysis, references and links to other databases. Published Molecule Pages contain an expert-authored review article that describes the biological activity, regulation and localization of the protein. This review is supplemented by highly structured data that illustrate protein-protein interactions, post-translational modifications, subcellular localization and biological function.

Prior to publication, Nature Publishing Group administers rigorous peer and editorial review of each Molecule Page. The published pages are citable by digital object identifiers (DOIs). All data in the Molecule Pages are freely available to the public.

XML Export

Our data are now available for export in a custom XML format. The reviewed data are included for published Molecule Pages, and the sequence and name assignments are included for all Molecule Pages.

500th Molecule Page published!

We are pleased to announce the publication of HB-EGF, our 500th Molecule Page. Each week, we publish several of these concise, free review articles on a diverse range of signaling molecules, from transcription factors to membrane receptors. Please see our new getting started guide for a quick overview of the anatomy of a published Molecule Page.

10 MOST RECENTLY PUBLISHED: expert-authored, peer-reviewed information on

• Adrenergic receptor alpha 2b
• Adrenergic receptor alpha 2c
• Muc4
• Lcmt2
• HB-EGF
• Pak1
• Itpk1
• Ubr5
• Rab35
• CAP1

View all published Molecule Pages

10 MOST POPULAR PAGES (December 2008):

1. mTOR
2. Muc4
3. HB-EGF
4. Catenin, beta
5. Pak1
6. G protein alpha 13
7. Plasma membrane calcium transporting ATPase isoform 4
8. Rab35
9. Adrenergic receptor alpha 2a
10. 5-Hydroxytryptamine receptor 2C

MOLECULE PAGE STATISTICS

MOLECULE PAGES FOCUSING ON:

EXPORTED DATA

Tab-delimited files relating the Molecule Pages to protein accession and NCBI Gene ID are availabe for ftp download at ftp://ftp.afcs.org/pub/mpdata/. We also provide text files with name, synonym, and sequence information.