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Protein Classes Section

Introduction

Groups of three or more proteins can be assigned to a Protein Class (based on homology and functional similarity), thus facilitating the creation of states. Without this feature, some authors would have to create many similar states representing complexes with each member of a class. The use of protein classes permits an author to create all of these complexes at the same time and group them into a class state that represents the prototypical complex.

For example, Gs alpha activates all membrane-bound adenylyl cyclases. The author of the Gs alpha molecule page may create one class state to represent all possible combinations of Gs alpha and membrane-bound adenylyl cyclases. The author should enter an intuitive class description for each protein class. At the end of this description the system adds the six-digit Molecule Page ID of the molecule page in which the class was originally created.

Another example is where the protein kinase C alpha author may want to define one class that contains all the protein kinase C isoforms, and a second class that contains the subset of phorbol ester-stimulated isoforms. Similarly, an author can create protein classes that he/she can use as interacting proteins, substrates, or enzymes that catalyze transitions between states. Obviously, these protein classes need not contain the author's protein.)

Clicking on the name of a class will take you to the class detail page, where can see a list of all of the members of the class, as well as any comments or citations added by the author.