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Molecule Page Sections


The Signaling Gateway Molecule Page database is a collaboration between a group at the University of California, San Diego (UCSD) and Nature Publishing Group (NPG). It is a resource for the storage, retrieval and display of complete and documented descriptions of the functional and biological properties of cellular proteins. The Molecule Page database aims to provide a highly structured summary of all known facts about proteins involved in cell signaling. Each record is written by an invited expert author and anonymously peer reviewed. The database will eventually grow to cover several thousand proteins and is entirely open access. There are no restrictions on the use of any of the available content. We hope it will enable a much more efficient exchange and distillation of information in the complex and burgeoning field of signal transduction.

Architecture of the Molecule Pages

Each Molecule Page is divided into two main sections; one contains information contributed by authors and the other contains data acquired automatically from public databases. Information in the author-entered section is contributed by an individual (or group) with expert knowledge of the protein. Information contributed by authors is peer reviewed under the direction of the editorial staff of NPG. The automated section of the Molecule Pages contains information about gene and protein sequences, domains, motifs, structure and so forth. Molecule Pages are published, electronically, by NPG. Published Molecule Pages are assigned a unique permanent digital object identifier (DOI) number and can be cited using the DOI number.

Protein Overview

The Protein Overview section contains the author or editor-designated name of the protein (Primary Name) as well as a chosen list of synonyms, the name of the Molecule Page author, mouse sequence information, and various biophysical properties of the protein.

screenshot of the protein overview section

Author-entered data sections

Automated data sections

Browser requirements

The Molecule Page Web site employs client-side scripting to provide a useful interface for all users. For this reason, all users should enable JavaScript in their browsers and use a recent version of a browser that properly supports JavaScript 1.1. The Web site has been tested extensively using various browsers derived from Mozilla version 1.0 and later, including Firefox, Netscape 6 and later, and also Microsoft Internet Explorer version 6. All of these browsers are free, and if you experience problems with the Web site, we suggest you install or upgrade to one of these. In order to view SVG images, you will need to install the free Adobe SVG Viewer available at http://www.adobe.com/svg/viewer/install/.

Citing Molecule Pages

All Molecule Pages that contain published author-entered data are assigned a digital object identifier (DOI). The DOI is unique to each molecule and also changes between updates of the same Molecule Page. Old versions of each Molecule Page entry will continue to be available online even after they have been superseded by new versions. This means that you can always be sure that the information you are citing now will be the same information that readers of your paper will be able to view in years to come. The DOI for each Molecule Pages entry is given near the top of each corresponding web page.

The full citation of a Molecule Page entry should include the names of all authors, the Molecule Page-designated name of the molecule, the name of the publication ("UCSD-Nature Molecule Pages"), the year of publication and the DOI. The following is an illustrative example:
Dessauer, C. Adenylyl cyclase type 5. UCSD-Nature Molecule Pages (2003). (doi:10.1038/mp.a000001.01)