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Protein A003584
Author-entered Data
V1.0, Peer Reviewed
Published 17 May 2005
Automated Data
Not Reviewed
As At Publication
Automated Data
Not Reviewed
Latest from 6 Jun 2014

Rpn8

Basis Sequence: Mouse

Latest intepro details retrieved 6 Jun 2014

doi:10.1038/mp.a003584.01  How to cite this Molecule Page

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Interpro Details
Database IDIPR024969 (Rpn11/EIF3F_C)
NameRpn11/EIF3F C-terminal domain
Abstract

This domain is found at the C terminus of many regulatory proteins, including the yeast proteasomal subunit Rpn11 and eukaryotic initiation factor 3 subunit F (eIF3f). The Rpn11 C-terminal domain is necessary for normal mitochondrial morphology and function and is thought to regulate the mitochondrial fission and tubulation processes []. The eIF3f C-terminal domain is critical for proper eIF3f activity in skeletal muscle through its interaction with mTOR (also known as FRAP, RAFT1 or RAPT) [].

Referenced By Molecule Page ProteinYes
Computational matchYes
Interpro TypeDomain
Gene Ontology-
Signatures & LinksPF13012 (PFAM), MitMem_reg, num proteins = 1834
Structure References-