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Protein A003584
Author-entered Data
V1.0, Peer Reviewed
Published 17 May 2005
Automated Data
Not Reviewed
As At Publication
Automated Data
Not Reviewed
Latest from 6 Jun 2014

UCSD Nature Molecule Pages
Published online: 17 May 2005 | doi:10.1038/mp.a003584.01

Rpn8

Basis Sequence: Mouse

H. Garrett R Thompson1, James P Brody1

1Department of Biomedical Engineering, University of California, Irvine, CA 92697, US.

Correspondence should be addressed to James P Brody: jpbrody@uci.edu

State summary
State name(Psmd7 P)
State descriptionRpn8-P
Computed nameRpn8 [Phosphorylation@unknown]
Cellular compartmentcytoplasm
 
State constituents
Protein nameRpn8
Covalent modificationsPhosphorylation@unknown
Small molecules boundNone
 
State functions

No functional data are associated with this state.

 
Author comments associated with this state

The authors have determined, by two-dimensional gel electrophoresis, that a posttranslational modification exists. Phosphorylated and unphosphorylated Rpn8 had similar mass but different isoelectric points. The phosphorylated form can be induced in vitro by the application of a proteasome inhibitor, PSI. The phosphorylated form did not exist in transformed cell lines.

 
Citations associated with this state
PM IDAuthorsTitleJournalPub Date
15221960Thompson HG, Harris JW, Brody JPPost-translationally modified S12, absent in transformed breast epithelial cells, is not associated with the 26S proteasome and is induced by proteasome inhibitor.Int J Cancer,
111, 3
1 Sep 2004