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Protein A003584
Author-entered Data
V1.0, Peer Reviewed
Published 17 May 2005
Automated Data
Not Reviewed
As At Publication
Automated Data
Not Reviewed
Latest from 6 Jun 2014

UCSD Nature Molecule Pages
Published online: 17 May 2005 | doi:10.1038/mp.a003584.01

Rpn8

Basis Sequence: Mouse

H. Garrett R Thompson1, James P Brody1

1Department of Biomedical Engineering, University of California, Irvine, CA 92697, US.

Correspondence should be addressed to James P Brody: jpbrody@uci.edu

Transition detail for
Rpn8/26S Proteasome  -->>  Rpn8-P
Multiple modification
Initial state
view transition graph transition view state details state
State name (Psma1) (Psma2) (Psma3) (Psma4) (Psma5) (Psma6) (Psmb4) (Psmb1) (Psmb8) (Psmb2) (Psmb9) (Psmb3) (Psma7) (Psmb5) (Psmb10) (Psmb6) (Psmb7) (Rpt2) (Psmc2) (Psmc3) (Psmc4) (Psmc5) (Psmc6) (Psmd1) (Psmd3) (Psmd2) (Psmd4) (Psmd5) (Psmd6) (Psmd7) (Psmd8) (Psmd9) (Psmd10) (Psmd11) (Psmd12) (Psmd13) (Psmd14)
State description Rpn8/26S Proteasome
Cellular localization Unknown
Protein name Rpn8
Covalent modifications None
Small molecules bound None
Protein name Psma1
Covalent modifications None
Small molecules bound None
Protein name Psma2
Covalent modifications None
Small molecules bound None
Protein name Psma3
Covalent modifications None
Small molecules bound None
Protein name Psma4
Covalent modifications None
Small molecules bound None
Protein name Psma5
Covalent modifications None
Small molecules bound None
Protein name Psma6
Covalent modifications None
Small molecules bound None
Protein name Psmb4
Covalent modifications None
Small molecules bound None
Protein name Psmb1
Covalent modifications None
Small molecules bound None
Protein name Psmb8
Covalent modifications None
Small molecules bound None
Protein name Psmb2
Covalent modifications None
Small molecules bound None
Protein name Psmb9
Covalent modifications None
Small molecules bound None
Protein name Psmb3
Covalent modifications None
Small molecules bound None
Protein name Psma7
Covalent modifications None
Small molecules bound None
Protein name Psmb5
Covalent modifications None
Small molecules bound None
Protein name Psmb10
Covalent modifications None
Small molecules bound None
Protein name Psmb6
Covalent modifications None
Small molecules bound None
Protein name Psmb7
Covalent modifications None
Small molecules bound None
Protein name Rpt2
Covalent modifications None
Small molecules bound None
Protein name Rpt1
Covalent modifications None
Small molecules bound None
Protein name Rpt5
Covalent modifications None
Small molecules bound None
Protein name Rpt3
Covalent modifications None
Small molecules bound None
Protein name Rpt6
Covalent modifications None
Small molecules bound None
Protein name Rpt4
Covalent modifications None
Small molecules bound None
Protein name Rpn2
Covalent modifications None
Small molecules bound None
Protein name Psmd3
Covalent modifications None
Small molecules bound None
Protein name Rpn1
Covalent modifications None
Small molecules bound None
Protein name Rpn10
Covalent modifications None
Small molecules bound None
Protein name Psmd5
Covalent modifications None
Small molecules bound None
Protein name Rpn7
Covalent modifications None
Small molecules bound None
Protein name Rpn12
Covalent modifications None
Small molecules bound None
Protein name Psmd9
Covalent modifications None
Small molecules bound None
Protein name Psmd10
Covalent modifications None
Small molecules bound None
Protein name Rpn6
Covalent modifications None
Small molecules bound None
Protein name Rpn5
Covalent modifications None
Small molecules bound None
Protein name Rpn9
Covalent modifications None
Small molecules bound None
Protein name Rpn11
Covalent modifications None
Small molecules bound None
Computed difference
Removed protein Psma1.
Removed protein Psma2.
Removed protein Psma3.
Removed protein Psma4.
Removed protein Psma5.
Removed protein Psma6.
Removed protein Psmb4.
Removed protein Psmb1.
Removed protein Psmb8.
Removed protein Psmb2.
Removed protein Psmb9.
Removed protein Psmb3.
Removed protein Psma7.
Removed protein Psmb5.
Removed protein Psmb10.
Removed protein Psmb6.
Removed protein Psmb7.
Removed protein Rpt2.
Removed protein Rpt1.
Removed protein Rpt5.
Removed protein Rpt3.
Removed protein Rpt6.
Removed protein Rpt4.
Removed protein Rpn2.
Removed protein Psmd3.
Removed protein Rpn1.
Removed protein Rpn10.
Removed protein Psmd5.
Removed protein Rpn7.
Removed protein Rpn12.
Removed protein Psmd9.
Removed protein Psmd10.
Removed protein Rpn6.
Removed protein Rpn5.
Removed protein Rpn9.
Removed protein Rpn11.
On protein Rpn8 (at position 1), added covalent modification Phosphorylation@unknown.
Final state
view transition graph transition view state details state
State name (Psmd7 P)
State description Rpn8-P
Cellular localization cytoplasm
Protein name Rpn8
Covalent modifications Phosphorylation@unknown
Small molecules bound None
 
Process data for this transition
 
Comments

This transition was observed in a human breast epithelial cell line.

 
Citations
PM IDAuthorsTitleJournalPub Date
15221960Thompson HG, Harris JW, Brody JPPost-translationally modified S12, absent in transformed breast epithelial cells, is not associated with the 26S proteasome and is induced by proteasome inhibitor.Int J Cancer,
111, 3
1 Sep 2004