signaling gateway home
registrationelectronic alerthelpcontact ussite guidesearch
cell signaling update signaling update home updates  news  research library featured articles conferences

Research library: browse by date

May 2002

2002: December | November | October | September | August | July | June | May | April | March | February | January

Other years: 2003 | 2004 | 2005 | 2006 | 2007

The Research Library categorizes, and provides access to, all recent signaling-related research published in the Nature Publishing Group journals. The selection is deliberately broad to facilitate access to all research impacting on the signaling community. Both primary research and review articles are included, as are 'News and Views' articles.

Click here for free access to the 'Featured Articles' section, with new articles every week.

Click here to browse by subject

article
The open pore conformation of potassium channels
Youxing Jiang, Alice Lee, Jiayun Chen, Martine Cadene, Brian T. Chait and Roderick MacKinnon
Nature 417, 523–526
(May 2002); doi:10.1038/417523a
| Summary | Full Text (HTML/PDF) |

news and views
Ion channels: An open and shut case
Maria Schumacher and John P. Adelman
Nature 417, 501–502
(May 2002); doi:10.1038/417501a
| Full Text (HTML/PDF) |

letters to nature
Transcription coactivator TRAP220 is required for PPARg2-stimulated adipogenesis
Kai Ge, Mohamed Guermah, Chao-Xing Yuan, Mitsuhiro Ito, Annika E. Wallberg, Bruce M. Spiegelman and Robert G. Roeder
Nature 417, 563–567
(May 2002); doi:10.1038/417563a
| First Paragraph | Full Text (HTML/PDF) |

letters to nature
Functional relationship of cytochrome c6 and plastocyanin in Arabidopsis
Rajeev Gupta, Zengyong He and Sheng Luan
Nature 417, 567–571
(May 2002); doi:10.1038/417567a
| First Paragraph | Full Text (HTML/PDF) |

news and views
Cell motility: Sharks' teeth and dunes
Laura M. Machesky
Nature 417, 494–497
(May 2002); doi:10.1038/417494a
| Full Text (HTML/PDF) |

article
E2F-dependent accumulation of hEmi1 regulates S phase entry by inhibiting APCCdh1
Jerry Y. Hsu, Julie D.R. Reimann, Claus S. Sřrensen, Jiri Lukas and Peter K. Jackson
Nature Cell Biology 4, 358–366
(May 2002); doi:10.1038/ncb785
| Abstract | Full Text (HTML/PDF) |

news and views
Conspiracy to disarm APC in interphase
Hartmut C. Vodermaier and Jan-Michael Peters
Nature Cell Biology 4, E119
(May 2002); doi:10.1038/ncb0502-e119
| Full Text (HTML/PDF) |

letters to nature
Emi1 is required for cytostatic factor arrest in vertebrate eggs
Julie D. R. Reimann and Peter K. Jackson
Nature 416, 850–854
(April 2002); doi:10.1038/416850a
| First Paragraph | Full Text (HTML/PDF) |

review article
Structural mechanisms of costimulation
Jean-Claude D. Schwartz, Xuewu Zhang, Stanley G. Nathenson and Steven C. Almo
Nature Immunology 3, 427–434
(May 2002); doi:10.1038/ni0502-427
| Abstract | Full Text (HTML/PDF) |

review article
T-cell development and the CD4-CD8 lineage decision
Ronald N. Germain
Nature Reviews Immunology 2, 309–322
(May 2002); doi:10.1038/nri798
| Abstract | Full Text (HTML/PDF) |

review article
MARGINAL-ZONE B CELLS
Flavius Martin and John F. Kearney
Nature Reviews Immunology 2, 323–335
(May 2002); doi:10.1038/nri799
| Abstract | Full Text (HTML/PDF) |

review article
Regulation of B-cell signal transduction by adaptor proteins
Tomohiro Kurosaki
Nature Reviews Immunology 2, 354–363
(May 2002); doi:10.1038/nri801
| Abstract | Full Text (HTML/PDF) |

perspectives
Timeline: Development of anti-TNF therapy for rheumatoid arthritis
Marc Feldmann
Nature Reviews Immunology 2, 364–371
(May 2002); doi:10.1038/nri802
| Abstract | Full Text (HTML/PDF) |

article
Mouse model of Prinzmetal angina by disruption of the inward rectifier Kir6.1
Takashi Miki, Masashi Suzuki, Tadao Shibasaki, Hiroko Uemura, Toshiaki Sato, Kaori Yamaguchi, Haruhiko Koseki, Toshihiko Iwanaga, Haruaki Nakaya and Susumu Seino
Nature Medicine 8, 466–472
(May 2002); doi:10.1038/nm0502-466
| Abstract | Full Text (HTML/PDF) |

article
Gene-microarray analysis of multiple sclerosis lesions yields new targets validated in autoimmune encephalomyelitis
Christopher Lock, Guy Hermans, Rosetta Pedotti, Andrea Brendolan, Eric Schadt, Hideki Garren, Annette Langer-Gould, Samuel Strober, Barbara Cannella, John Allard, Paul Klonowski, Angela Austin, Nagin Lad, Naftali Kaminski, Stephen J. Galli, Jorge R. Oksenberg, Cedric S. Raine, Renu Heller and Lawrence Steinman
Nature Medicine 8, 500–508
(May 2002); doi:10.1038/nm0502-500
| Abstract | Full Text (HTML/PDF) |

news and views
An array of possibilities for multiple sclerosis
Stephen M. Tompkins and Stephen D. Miller
Nature Medicine 8, 451–453
(May 2002); doi:10.1038/nm0502-451
| Full Text (HTML/PDF) |

review article
Papillomaviruses and cancer: from basic studies to clinical application
Harald zur Hausen
Nature Reviews Cancer 2, 342–350
(May 2002); doi:10.1038/nrc798
| Abstract | Full Text (HTML/PDF) |

review article
ONCOGENIC TYROSINE KINASES AND THE DNA-DAMAGE RESPONSE
Tomasz Skorski
Nature Reviews Cancer 2, 351–360
(May 2002); doi:10.1038/nrc799
| Abstract | Full Text (HTML/PDF) |

review article
Aids-related malignancies
Chris Boshoff and Robin Weiss
Nature Reviews Cancer 2, 373–382
(May 2002); doi:10.1038/nrc797
| Abstract | Full Text (HTML/PDF) |

article
Disruption of CREB function in brain leads to neurodegeneration
Theo Mantamadiotis, Thomas Lemberger, Susanne C. Bleckmann, Heidrun Kern, Oliver Kretz, Ana Martin Villalba, François Tronche, Christoph Kellendonk, Daniel Gau, Josef Kapfhammer, Christiane Otto, Wolfgang Schmid and Günther Schütz
Nature Genetics 31, 47–54
(May 2002); doi:10.1038/ng882
| Abstract | Full Text (HTML/PDF) |

article
Extrasynaptic NMDARs oppose synaptic NMDARs by triggering CREB shut-off and cell death pathways
Giles E. Hardingham, Yuko Fukunaga and Hilmar Bading
Nature Neuroscience 5, 405–414
(May 2002); doi:10.1038/nn835
| Abstract | Full Text (HTML/PDF) |

news and views
What a privilege to reside at the synapse: NMDA receptor signaling to CREB
Antonella Riccio and David D. Ginty
Nature Neuroscience 5, 389–390
(May 2002); doi:10.1038/nn0502-389
| Full Text (HTML/PDF) |

article
Cyclic AMP-dependent protein kinase phosphorylation facilitates GABAB receptor-effector coupling
Andrés Couve, Philip Thomas, Andrew R. Calver, Warren D. Hirst, Menelas N. Pangalos, Frank S. Walsh, Trevor G. Smart and Stephen J. Moss
Nature Neuroscience 5, 415–424
(May 2002); doi:10.1038/nn833
| Abstract | Full Text (HTML/PDF) |

article
A protein kinase A-dependent molecular switch in synapsins regulates neurite outgrowth
Hung-Teh Kao, Hong-jun Song, Barbara Porton, Guo-li Ming, Josephine Hoh, Michael Abraham, Andrew J. Czernik, Vincent A. Pieribone, Mu-ming Poo and Paul Greengard
Nature Neuroscience 5, 431–437
(May 2002); doi:10.1038/nn840
| Abstract | Full Text (HTML/PDF) |

Research News
A new blueprint for plant pathogen resistance
Heribert Hirt
Nature Biotechnology 20, 450–451
(May 2002); doi:10.1038/nbt0502-450
| Full Text (HTML/PDF) |

research article
An HGF-MSP chimera disassociates the trophic properties of scatter factors from their pro-invasive activity
Paolo Michieli, Silvia Cavassa, Cristina Basilico, Annarita De Luca, Massimiliano Mazzone, Cinzia Asti, Riccardo Chiusaroli, Mario Guglielmi, Paola Bossů, Francesco Colotta, Gianfranco Caselli and Paolo M. Comoglio
Nature Biotechnology 20, 488–495
(May 2002); doi:10.1038/nbt0502-488
| Abstract | Full Text (HTML/PDF) |

news and views
Locked but not loaded
Elizabeth H. Cox
Nature Structural Biology 9, 325
(May 2002); doi:10.1038/nsb0502-325
| Full Text (HTML/PDF) |

analysis
Comparative assessment of large-scale data sets of protein-protein interactions
Christian von Mering, Roland Krause, Berend Snel, Michael Cornell, Stephen G. Oliver, Stanley Fields and Peer Bork
Nature 417, 399–403
(May 2002); doi:10.1038/nature750
| Abstract | Full Text (HTML/PDF) |

article
Prokineticin 2 transmits the behavioural circadian rhythm of the suprachiasmatic nucleus
Michelle Y. Cheng, Clayton M. Bullock, Chuanyu Li, Alex G. Lee, Jason C. Bermak, James Belluzzi, David R. Weaver, Frances M. Leslie and Qun-Yong Zhou
Nature 417, 405–410
(May 2002); doi:10.1038/417405a
| Summary | Full Text (HTML/PDF) |

news and views
Circadian rhythms: A gut feeling for time
Michael H. Hastings
Nature 417, 391–392
(May 2002); doi:10.1038/417391a
| Full Text (HTML/PDF) |

article
Adaptation in the chemotactic guidance of nerve growth cones
Guo-li Ming, Scott T. Wong, John Henley, Xiao-bing Yuan, Hong-jun Song, Nicholas C. Spitzer and Mu-Ming Poo
Nature 417, 411–418
(May 2002); doi:10.1038/nature745
| Abstract | Full Text (HTML/PDF) |

letters to nature
Netrin-1-mediated axon outgrowth requires deleted in colorectal cancer-dependent MAPK activation
Christelle Forcet, Elke Stein, Laurent Pays, Véronique Corset, Fabien Llambi, Marc Tessier-Lavigne and Patrick Mehlen
Nature 417, 443–447
(May 2002); doi:10.1038/nature748
| First Paragraph | Full Text (HTML/PDF) |

letters to nature
HDAC6 is a microtubule-associated deacetylase
Charlotte Hubbert, Amaris Guardiola, Rong Shao, Yoshiharu Kawaguchi, Akihiro Ito, Andrew Nixon, Minoru Yoshida, Xiao-Fan Wang and Tso-Pang Yao
Nature 417, 455–458
(May 2002); doi:10.1038/417455a
| First Paragraph | Full Text (HTML/PDF) |

hypothesis
The origins of protein phosphorylation
Philip Cohen
Nature Cell Biology 4, E127
(May 2002); doi:10.1038/ncb0502-e127
| Abstract | Full Text (HTML/PDF) |

article
Regulation of the TCRa repertoire by the survival window of CD4+CD8+ thymocytes
Jian Guo, Abbas Hawwari, Hong Li, Zuoming Sun, Sanjeev K. Mahanta, Dan R. Littman, Michael S. Krangel and You-Wen He
Nature Immunology 3, 469–476
(May 2002); doi:10.1038/ni791
| Abstract | Full Text (HTML/PDF) |

news and views
Corticosteroids and cardioprotection
Christoph Thiemermann
Nature Medicine 8, 453–455
(May 2002); doi:10.1038/nm0502-453
| Full Text (HTML/PDF) |

article
Calcium-pump inhibitors induce functional surface expression of ΔF508-CFTR protein in cystic fibrosis epithelial cells
Marie E. Egan, Judith Glöckner-Pagel, Catherine A. Ambrose, Paula A. Cahill, Lamiko Pappoe, Naomi Balamuth, Edward Cho, Susan Canny, Carsten A. Wagner, John Geibel and Michael J. Caplan
Nature Medicine 8, 485–492
(May 2002); doi:10.1038/nm0502-485
| Abstract | Full Text (HTML/PDF) |

news and views
Nicotinic receptors: Addiction's smoking gun?
Ann E. Kelley
Nature Medicine 8, 447–449
(May 2002); doi:10.1038/nm0502-447
| Full Text (HTML/PDF) |

news and views
CREB family transcription factors inhibit neuronal suicide
Ted M. Dawson and David D. Ginty
Nature Medicine 8, 450–451
(May 2002); doi:10.1038/nm0502-450
| Full Text (HTML/PDF) |

review article
Modelling the molecular circuitry of cancer
William C. Hahn and Robert A. Weinberg
Nature Reviews Cancer 2, 331–341
(May 2002); doi:10.1038/nrc795
| Abstract | Full Text (HTML/PDF) |

review article
Gli and hedgehog in cancer: tumours, embryos and stem cells
Ariel Ruiz i Altaba, Pilar Sánchez and Nadia Dahmane
Nature Reviews Cancer 2, 361–372
(May 2002); doi:10.1038/nrc796
| Abstract | Full Text (HTML/PDF) |

letter
Genetic evidence that oxidative derivatives of retinoic acid are not involved in retinoid signaling during mouse development
Karen Niederreither, Suzan Abu-Abed, Brigitte Schuhbaur, Martin Petkovich, Pierre Chambon and Pascal Dollé
Nature Genetics 31, 84–88
(May 2002); doi:10.1038/ng876
| First Paragraph | Full Text (HTML/PDF) |

news and views
Retinoid metabolism: a balancing act
Thomas Perlmann
Nature Genetics 31, 7–9
(May 2002); doi:10.1038/ng877
| Full Text (HTML/PDF) |

correspondence
GenMAPP, a new tool for viewing and analyzing microarray data on biological pathways
Kam D. Dahlquist, Nathan Salomonis, Karen Vranizan, Steven C. Lawlor and Bruce R. Conklin
Nature Genetics 31, 19–20
(May 2002); doi:10.1038/ng0502-19
| Full Text (HTML/PDF) |

research article
Reprogramming fibroblasts to express T-cell functions using cell extracts
Anne-Mari Hĺkelien, Helga B. Landsverk, James M. Robl, Bjřrn S. Skĺlhegg and Philippe Collas
Nature Biotechnology 20, 460–466
(May 2002); doi:10.1038/nbt0502-460
| Abstract | Full Text (HTML/PDF) |

article
Mechanism of glutamate receptor desensitization
Yu Sun, Rich Olson, Michelle Horning, Neali Armstrong, Mark Mayer and Eric Gouaux
Nature 417, 245–253
(May 2002); doi:10.1038/417245a
| Summary | Full Text (HTML/PDF) |

news and views
Ion channels: How to be desensitized
Christian Rosenmund and Michael Mansour
Nature 417, 238–239
(May 2002); doi:10.1038/417238a
| Full Text (HTML/PDF) |

article
Targeted pharmacological depletion of serum amyloid P component for treatment of human amyloidosis
M. B. Pepys, J. Herbert, W. L. Hutchinson, G. A. Tennent, H. J. Lachmann, J. R. Gallimore, L. B. Lovat, T. Bartfai, A. Alanine, C. Hertel, T. Hoffmann, R. Jakob-Roetne, R. D. Norcross, J. A. Kemp, K. Yamamura, M. Suzuki, G. W. Taylor, S. Murray, D. Thompson, A. Purvis, S. Kolstoe, S. P. Wood and P. N. Hawkins
Nature 417, 254–259
(May 2002); doi:10.1038/417254a
| Summary | Full Text (HTML/PDF) |

news and views
Amyloid diseases: Small drugs lead the attack
Leslie Iversen
Nature 417, 231–233
(May 2002); doi:10.1038/417231a
| Full Text (HTML/PDF) |

letters to nature
The Wnt/calcium pathway activates NF-AT and promotes ventral cell fate in Xenopus embryos
Takeo Saneyoshi, Shoen Kume, Yoshiharu Amasaki and Katsuhiko Mikoshiba
Nature 417, 295–299
(May 2002); doi:10.1038/417295a
| First Paragraph | Full Text (HTML/PDF) |

news and views
Developmental biology: Signalling polarity
Randall T. Moon and Kavita Shah
Nature 417, 239–240
(May 2002); doi:10.1038/417239a
| Full Text (HTML/PDF) |

letters to nature
The dynamics of actin-based motility depend on surface parameters
Anne Bernheim-Groswasser, Sebastian Wiesner, Roy M. Golsteyn, Marie-France Carlier and Cécile Sykes
Nature 417, 308–311
(May 2002); doi:10.1038/417308a
| First Paragraph | Full Text (HTML/PDF) |

letters to nature
A common mechanism of action for three mood-stabilizing drugs
Robin S. B. Williams, Lili Cheng, Anne W. Mudge and Adrian J. Harwood
Nature 417, 292–295
(May 2002); doi:10.1038/417292a
| First Paragraph | Full Text (HTML/PDF) |

review article
Integration of calcium and Ras signalling
Peter J. Cullen and Peter J. Lockyer
Nature Reviews Molecular Cell Biology 3, 339–348
(May 2002); doi:10.1038/nrm808
| Abstract | Full Text (HTML/PDF) |

article
The CD40-TRAF6 axis controls affinity maturation and the generation of long-lived plasma cells
Cory L. Ahonen, Eric M. Manning, Loren D. Erickson, Brian P. O'Connor, Evan F. Lind, Steven S. Pullen, Marilyn R. Kehry and Randolph J. Noelle
Nature Immunology 3, 451–456
(May 2002); doi:10.1038/ni792
| Abstract | Full Text (HTML/PDF) |

news and views
A role for Toll in autoimmunity
Arthur M. Krieg
Nature Immunology 3, 423–424
(May 2002); doi:10.1038/ni0502-423
| Full Text (HTML/PDF) |

article
A pivotal role of cytosolic phospholipase A2 in bleomycin-induced pulmonary fibrosis
Takahide Nagase, Naonori Uozumi, Satoshi Ishii, Yoshihiro Kita, Hiroshi Yamamoto, Eijiro Ohga, Yasuyoshi Ouchi and Takao Shimizu
Nature Medicine 8, 480–484
(May 2002); doi:10.1038/nm0502-480
| Abstract | Full Text (HTML/PDF) |

letter
b-cell-specific deletion of the Igf1 receptor leads to hyperinsulinemia and glucose intolerance but does not alter b-cell mass
Rohit N. Kulkarni, Martin Holzenberger, David Q. Shih, Umut Ozcan, Markus Stoffel, Mark A. Magnuson and C. Ronald Kahn
Nature Genetics 31, 111–115
(May 2002); doi:10.1038/ng872
| First Paragraph | Full Text (HTML/PDF) |

letters to nature
Minocycline inhibits cytochrome c release and delays progression of amyotrophic lateral sclerosis in mice
Shan Zhu, Irina G. Stavrovskaya, Martin Drozda, Betty Y. S. Kim, Victor Ona, Mingwei Li, Satinder Sarang, Allen S. Liu, Dean M. Hartley, Du Chu Wu, Steven Gullans, Robert J. Ferrante, Serge Przedborski, Bruce S. Kristal and Robert M. Friedlander
Nature 417, 74–78
(May 2002); doi:10.1038/417074a
| First Paragraph | Full Text (HTML/PDF) |

letters to nature
Glutamate-receptor-interacting protein GRIP1 directly steers kinesin to dendrites
Mitsutoshi Setou, Dae-Hyung Seog, Yosuke Tanaka, Yoshimitsu Kanai, Yosuke Takei, Masahiko Kawagishi & Nobutaka Horokawa
Nature 417, 83–87
(May 2002); doi:10.1038/nature743
| First Paragraph | Full Text (HTML/PDF) |

letters to nature
Extensive and divergent circadian gene expression in liver and heart
Kai-Florian Storch, Ovidiu Lipan, Igor Leykin, N. Viswanathan, Fred C. Davis, Wing H. Wong & Charles J. Weitz
Nature 417, 78–83
(May 2002); doi:10.1038/nature744
| First Paragraph | Full Text (HTML/PDF) |

letters to nature
Rapid regulation of steroidogenesis by mitochondrial protein import
Himangshu S. Bose, Vishwanath R. Lingappa and Walter L. Miller
Nature 417, 87–91
(May 2002); doi:10.1038/417087a
| First Paragraph | Full Text (HTML/PDF) |

letters to nature
Neutrophil elastase targets virulence factors of enterobacteria
Yvette Weinrauch, Doreen Drujan, Steven D. Shapiro, Jerrold Weiss and Arturo Zychlinsky
Nature 417, 91–94
(May 2002); doi:10.1038/417091a
| First Paragraph | Full Text (HTML/PDF) |

news and views
Cell polarity: Oskar seeks PARtner for a stable relationship
Simon L. Bullock and David Ish-Horowicz
Nature Cell Biology 4, E117
(May 2002); doi:10.1038/ncb0502-e117
| Full Text (HTML/PDF) |

commentary
Taking a bite: proteasomal protein processing
Michael Rape and Stefan Jentsch
Nature Cell Biology 4, E113
(May 2002); doi:10.1038/ncb0502-e113
| Full Text (HTML/PDF) |

article
Ras signalling on the endoplasmic reticulum and the Golgi
Vi K. Chiu, Trever Bivona, Angela Hach, J. Bernard Sajous, Joseph Silletti, Heidi Wiener, Ronald L. Johnson II, Adrienne D. Cox and Mark R. Philips
Nature Cell Biology 4, 343–350
(May 2002); doi:10.1038/ncb783
| Abstract | Full Text (HTML/PDF) |

article
Frodo interacts with Dishevelled to transduce Wnt signals
Joachim Gloy, Hiroki Hikasa and Sergei Y. Sokol
Nature Cell Biology 4, 351–357
(May 2002); doi:10.1038/ncb784
| Abstract | Full Text (HTML/PDF) |

article
A new nuclear component of the Wnt signalling pathway
Barry Thompson, Fiona Townsley, Rina Rosin-Arbesfeld, Hannah Musisi and Mariann Bienz
Nature Cell Biology 4, 367–373
(May 2002); doi:10.1038/ncb786
| Abstract | Full Text (HTML/PDF) |

news and views
Getting legless with a Pygopus
Sarah Greaves
Nature Cell Biology 4, E124
(May 2002); doi:10.1038/ncb0502-e124
| Full Text (HTML/PDF) |

brief communication
Maintenance of replication forks and the S-phase checkpoint by Cdc18p and Orp1p
Hiroshi Murakami, Stephanie K. Yanow, Dominic Griffiths, Makoto Nakanishi and Paul Nurse
Nature Cell Biology 4, 384–388
(May 2002); doi:10.1038/ncb789
| First Paragraph | Full Text (HTML/PDF) |

article
Par-1 regulates stability of the posterior determinant Oskar by phosphorylation
Veit Riechmann, Gustavo J. Gutierrez, Paolo Filardo, Angel R. Nebreda and Anne Ephrussi
Nature Cell Biology 4, 337–342
(May 2002); doi:10.1038/ncb782
| Abstract | Full Text (HTML/PDF) |

review article
The subcellular destinations of apc proteins
Mariann Bienz
Nature Reviews Molecular Cell Biology 3, 328–338
(May 2002); doi:10.1038/nrm806
| Abstract | Full Text (HTML/PDF) |

review article
The mre11 complex: at the crossroads of dna repair and checkpoint signalling
Damien D'Amours and Stephen P. Jackson
Nature Reviews Molecular Cell Biology 3, 317–327
(May 2002); doi:10.1038/nrm805
| Abstract | Full Text (HTML/PDF) |

article
A critical role for the cytoplasmic tail of pTa in T lymphocyte development
Iannis Aifantis, Christine Borowski, Fotini Gounari, H. Daniel Lacorazza, Janko Nikolich-Zugich and Harald von Boehmer
Nature Immunology 3, 483–488
(May 2002); doi:10.1038/ni779
| Abstract | Full Text (HTML/PDF) |

article
Tracing lymphopoiesis with the aid of a pTa-controlled reporter gene
Fotini Gounari, Iannis Aifantis, Colin Martin, Hans-Joerg Fehling, Sonja Hoeflinger, Philip Leder, Harald von Boehmer and Boris Reizis
Nature Immunology 3, 489–496
(May 2002); doi:10.1038/ni778
| Abstract | Full Text (HTML/PDF) |

news and views
A new spin on an unusual tail
Nigel Killeen
Nature Immunology 3, 419–421
(May 2002); doi:10.1038/ni0502-419
| Full Text (HTML/PDF) |

article
Notch-RBP-J signaling is involved in cell fate determination of marginal zone B cells
Kenji Tanigaki, Hua Han, Norio Yamamoto, Kei Tashiro, Masaya Ikegawa, Kazuki Kuroda, Akira Suzuki, Toru Nakano and Tasuku Honjo
Nature Immunology 3, 443–450
(May 2002); doi:10.1038/ni793
| Abstract | Full Text (HTML/PDF) |

article
A neuronal receptor, neuropilin-1, is essential for the initiation of the primary immune response
Rafačle Tordjman, Yves Lepelletier, Valérie Lemarchandel, Marie Cambot, Philippe Gaulard, Olivier Hermine and Paul-Henri Roméo
Nature Immunology 3, 477–482
(May 2002); doi:10.1038/ni789
| Abstract | Full Text (HTML/PDF) |

news and views
Neuropilin-1: another neuronal molecule in the "immunological synapse"
Christoph Wülfing and Fabio Rupp
Nature Immunology 3, 418–419
(May 2002); doi:10.1038/ni0502-418
| Full Text (HTML/PDF) |

article
Acute cardiovascular protective effects of corticosteroids are mediated by non-transcriptional activation of endothelial nitric oxide synthase
Ali Hafezi-Moghadam, Tommaso Simoncini, Zequan Yang, Florian P. Limbourg, Jean-Christophe Plumier, Michela C. Rebsamen, Chung-Ming Hsieh, Dao-Shan Chui, Kennard L. Thomas, Alyson J. Prorock, Victor E. Laubach, Michael A. Moskowitz, Brent A. French, Klaus Ley and James K. Liao
Nature Medicine 8, 473–479
(May 2002); doi:10.1038/nm0502-473
| Abstract | Full Text (HTML/PDF) |

article
ErbB2 is essential in the prevention of dilated cardiomyopathy
Steven A. Crone, You-Yang Zhao, Lian Fan, Yusu Gu, Susumu Minamisawa, Yang Liu, Kirk L. Peterson, Ju Chen, Ronald Kahn, Gianluigi Condorelli, John Ross Jr, Kenneth R. Chien and Kuo-Fen Lee
Nature Medicine 8, 459–465
(May 2002); doi:10.1038/nm0502-459
| Abstract | Full Text (HTML/PDF) |

article
Bop encodes a muscle-restricted protein containing MYND and SET domains and is essential for cardiac differentiation and morphogenesis
Paul D. Gottlieb, Stephanie A. Pierce, Robert J. Sims III, Hiroyuki Yamagishi, Elizabeth K. Weihe, June V. Harriss, Shanna D. Maika, William A. Kuziel, Heather L. King, Eric N. Olson, Osamu Nakagawa and Deepak Srivastava
Nature Genetics 31, 25–32
(May 2002); doi:10.1038/ng866
| Abstract | Full Text (HTML/PDF) |

letter
Low-penetrance susceptibility to breast cancer due to CHEK2*1100delC in noncarriers of BRCA1 or BRCA2 mutations
Hanne Meijers-Heijboer, Ans van den Ouweland, Jan Klijn, Marijke Wasielewski, Anja de Snoo, Rogier Oldenburg, Antoinette Hollestelle, Mark Houben, Ellen Crepin, Monique van Veghel-Plandsoen, Fons Elstrodt, Cornelia van Duijn, Carina Bartels, Carel Meijers, Mieke Schutte, Lesley McGuffog, Deborah Thompson, Douglas F. Easton, Nayanta Sodha, Sheila Seal, Rita Barfoot, Jon Mangion, Jenny Chang-Claude, Diana Eccles, Rosalind Eeles, D Gareth Evans, Richard Houlston, Victoria Murday, Steven Narod, Tamara Peretz, Julian Peto, Catherine Phelan, Hong Xiang Zhang, Csilla Szabo, Peter Devilee, David Goldgar, P Andrew Futreal, Katherine L. Nathanson, Barbara L. Weber, Nazneen Rahman and Michael R. Stratton
Nature Genetics 31, 55–59
(May 2002); doi:10.1038/ng879
| First Paragraph | Full Text (HTML/PDF) |

news and views
CHEKs and balances: accounting for breast cancer
Lawrence C. Brody
Nature Genetics 31, 3–4
(May 2002); doi:10.1038/ng0502-3
| Full Text (HTML/PDF) |

review article
LIFE IS A JOURNEY: A GENETIC LOOK AT NEOCORTICAL DEVELOPMENT
Amitabh Gupta, Li-Huei Tsai and Anthony Wynshaw-Boris
Nature Reviews Genetics 3, 342–355
(May 2002); doi:10.1038/nrg799
| Abstract | Full Text (HTML/PDF) |

review article
CHILDHOOD ABSENCE EPILEPSY: GENES, CHANNELS, NEURONS AND NETWORKS
Vincenzo Crunelli and Nathalie Leresche
Nature Reviews Neuroscience 3, 371–382
(May 2002); doi:10.1038/nrn811
| Abstract | Full Text (HTML/PDF) |

review article
POTENTIAL CARDIOPROTECTIVE ACTIONS OF NO-RELEASING ASPIRIN
John L. Wallace, Louis J. Ignarro and Stefano Fiorucci
Nature Reviews Drug Discovery 1, 375–382
(May 2002); doi:10.1038/nrd794
| Abstract | Full Text (HTML/PDF) |

review article
NEW THERAPEUTICS THAT MODULATE CHEMOKINE NETWORKS
Matthias K. Schwarz and Timothy N. C. Wells
Nature Reviews Drug Discovery 1, 347–358
(May 2002); doi:10.1038/nrd795
| Abstract | Full Text (HTML/PDF) |

letter
SH3-dependent stimulation of Src-family kinase autophosphorylation without tail release from the SH2 domain in vivo
Edwina C. Lerner and Thomas E. Smithgall
Nature Structural Biology 9, 365–369
(May 2002); doi:10.1038/nsb782
| Abstract | Full Text (HTML/PDF) |

 Nature Publishing Group

HOME | SIGNALING UPDATE | MOLECULE PAGES | DATA CENTER | ABOUT US
registration | e-alert | help | contact us | site guide | search

© 2002-2008 Nature Publishing Group

Privacy Policy