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The Research Library categorizes, and provides access to, all recent signaling-related research published in the Nature Publishing Group journals. The selection is deliberately broad to facilitate access to all research impacting on the signaling community. Both primary research and review articles are included, as are 'News and Views' articles.
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article
Curvature of clathrin-coated pits driven by epsin
Marijn G. J. Ford, Ian G. Mills, Brian J. Peter, Yvonne Vallis, Gerrit J. K. Praefcke, Philip R. Evans and Harvey T. McMahon
Nature 419, 361–366
(26 September 2002); doi:10.1038/nature01020
| Summary | Full Text (HTML / PDF) |
news and views
Membrane transport: The making of a vesicle
Anne A. Schmidt
Nature 419, 347–349
(26 September 2002); doi:10.1038/419347a
| Full Text (HTML / PDF) |
article
The harlequin mouse mutation downregulates apoptosis-inducing factor
Jeffrey A. Klein, Chantal M. Longo-Guess, Marlies P. Rossmann, Kevin L. Seburn, Ronald E. Hurd, Wayne N. Frankel, Roderick T. Bronson and Susan L. Ackerman
Nature 419, 367–374
(26 September 2002); doi:10.1038/nature01034
| Summary | Full Text (HTML / PDF) |
letters to nature
Pleiotropic defects in lymphocyte activation caused by caspase-8 mutations lead to human immunodeficiency
Hyung J. Chun, Lixin Zheng, Manzoor Ahmad, Jin Wang, Christina K. Speirs, Richard M. Siegel, Janet K. Dale, Jennifer Puck, Joie Davis, Craig G. Hall, Suzanne Skoda-Smith, T. Prescott Atkinson, Stephen E. Straus and Michael J. Lenardo
Nature 419, 395–399
(26 September 2002); doi:10.1038/nature01063
| First Paragraph | Full Text (HTML / PDF) |
letters to nature
A putative lipid transfer protein involved in systemic resistance signalling in Arabidopsis
Ana M. Maldonado , Peter Doerner, Richard A. Dixon, Chris J. Lamb and Robin K. Cameron
Nature 419, 399–403
(26 September 2002); doi:10.1038/nature00962
| First Paragraph | Full Text (HTML / PDF) |
letters to nature
A cryptic protease couples deubiquitination and degradation by the proteasome
Tingting Yao and Robert E. Cohen
Nature 419, 403–407
(26 September 2002); doi:10.1038/nature01071
| First Paragraph | Full Text (HTML / PDF) |
news and views
Cell biology: Unchaining the condemned
Keith D. Wilkinson
Nature 419, 351–353
(26 September 2002); doi:10.1038/419351a
| Full Text (HTML / PDF) |
news and views
Virology: Ins and outs
Amanda Tromans
Nature 419, 349
(26 September 2002); doi:10.1038/419349a
| Full Text (HTML / PDF) |
article
Filamin is essential in actin cytoskeletal assembly mediated by p21-activated kinase 1
Ratna K. Vadlamudi, Feng Li, Liana Adam, Diep Nguyen, Yasutaka Ohta, Thomas P. Stossel and Rakesh Kumar
Nature Cell Biology 4, 681–690
(September 2002); doi:10.1038/ncb838
| Abstract | Full Text (HTML/PDF) |
article
Imaging actin and dynamin recruitment during invagination of single clathrin-coated pits
Christien J. Merrifield, Morris E. Feldman, Lei Wan and Wolfhard Almers
Nature Cell Biology 4, 691–698
(September 2002); doi:10.1038/ncb837
| Abstract | Full Text (HTML/PDF) |
brief communication
Invasive cell migration is initiated by guided growth of long cellular extensions
Tudor A. Fulga and Pernille Rørth
Nature Cell Biology 4, 715–719
(September 2002); doi:10.1038/ncb848
| First Paragraph | Full Text (HTML/PDF) |
news and views
Unconventional ways to travel
Markus Schober and Norbert Perrimon
Nature Cell Biology 4, E211
(September 2002); doi:10.1038/ncb0902-e211
| Full Text (HTML/PDF) |
news and views
The progress zone — alive or dead?
Cheryll Tickle and Lewis Wolpert
Nature Cell Biology 4, E216
(September 2002); doi:10.1038/ncb0902-e216
| Full Text (HTML/PDF) |
review article
STATS: transcriptional control and biological impact
David E. Levy and J. E. Darnell Jr
Nature Reviews Molecular Cell Biology 3, 651–662
(September 2002); doi:10.1038/nrm909
| Summary | Full Text (HTML / PDF) |
perspectives
Timeline: Cyclic nucleotide research — still expanding after half a century
Joseph A. Beavo and Laurence L. Brunton
Nature Reviews Molecular Cell Biology 3, 710–718
(September 2002); doi:10.1038/nrm911
| Summary | Full Text (HTML / PDF) |
review article
Natural killer cell activation in mice and men: different triggers for similar weapons?
Francesco Colucci, James P. Di Santo and Paul J. Leibson
Nature Immunology 3, 807–813
(September 2002); doi:10.1038/ni0902-807
| Abstract | Full Text (HTML/PDF) |
article
AID-dependent somatic hypermutation occurs as a DNA single-strand event in the BL2 cell line
Ahmad Faili, Said Aoufouchi, Quentin Guéranger, Carole Zober, Anne Léon, Barbara Bertocci, Jean-Claude Weill and Claude-Agnès Reynaud
Nature Immunology 3, 815–821
(September 2002); doi:10.1038/ni826
| Abstract | Full Text (HTML/PDF) |
news and views
Does AID need another aid?
Tasuku Honjo
Nature Immunology 3, 800–801
(September 2002); doi:10.1038/ni0902-800
| Full Text (HTML/PDF) |
review article
WASp in immune-system organization and function
Adrian J. Thrasher
Nature Reviews Immunology 2, 635–646
(September 2002); doi:10.1038/nri884
| Summary | Full Text (HTML / PDF) |
review article
Natural killer cells and pregnancy
Ashley Moffett-King
Nature Reviews Immunology 2, 656–663
(September 2002); doi:10.1038/nri886
| Summary | Full Text (HTML / PDF) |
article
SHIP-deficient mice are severely osteoporotic due to increased numbers of hyper-resorptive osteoclasts
Sunao Takeshita, Noriyuki Namba, Jenny J. Zhao, Yebin Jiang, Harry K. Genant, Matthew J. Silva, Michael D. Brodt, Cheryl D. Helgason, Janet Kalesnikoff, Michael J. Rauh, R. Keith Humphries, Gerald Krystal, Steven L. Teitelbaum and F. Patrick Ross
Nature Medicine 8, 943–949
(September 2002); doi:10.1038/nm752
| Abstract | Full Text (HTML/PDF) |
article
Multi-pronged inhibition of airway hyper-responsiveness and inflammation by lipoxin A4
Bruce D. Levy, George T. De Sanctis, Pallavi R. Devchand, Eugene Kim, Kate Ackerman, Birgitta A. Schmidt, Wojciech Szczeklik, Jeffrey M. Drazen and Charles N. Serhan
Nature Medicine 8, 1018–1023
(September 2002); doi:10.1038/nm748
| Abstract | Full Text (HTML/PDF) |
news and views
'Good' lipids for asthma
Marc Peters-Golden
Nature Medicine 8, 931–932
(September 2002); doi:10.1038/nm0902-931
| Full Text (HTML/PDF) |
commentary
A reevaluation of integrins as regulators of angiogenesis
Richard O. Hynes
Nature Medicine 8, 918–921
(September 2002); doi:10.1038/nm0902-918
| Full Text (HTML/PDF) |
review article
The bcl2 family: regulators of the cellular life-or-death switch
Suzanne Cory and Jerry M. Adams
Nature Reviews Cancer 2, 647–656
(September 2002); doi:10.1038/nrc883
| Summary | Full Text (HTML / PDF) |
letter
New genes involved in cancer identified by retroviral tagging
Takeshi Suzuki, Haifa Shen, Keiko Akagi, Herbert C Morse, III James D Malley, Daniel Q Naiman, Nancy A Jenkins and Neal G Copeland
Nature Genetics 32, 166–174
(September 2002); doi:10.1038/ng949
| First Paragraph | Full Text (HTML/PDF) |
letter
BRCA1 induces DNA damage recognition factors and enhances nucleotide excision repair
Anne-Renee Hartman and James M. Ford
Nature Genetics 32, 180–184
(September 2002); doi:10.1038/ng953
| First Paragraph | Full Text (HTML/PDF) |
letter
Survival signaling mediated by c-Jun NH2-terminal kinase in transformed B lymphoblasts
Patricia Hess, German Pihan, Charles L. Sawyers, Richard A. Flavell and Roger J. Davis
Nature Genetics 32, 201–205
(September 2002); doi:10.1038/ng946
| First Paragraph | Full Text (HTML/PDF) |
brief communication
A-kinase anchoring proteins in amygdala are involved in auditory fear memory
Marta A.P. Moita, Raphael Lamprecht, Karim Nader and Joseph E. LeDoux
Nature Neuroscience 5, 837–838
(September 2002); doi:10.1038/nn901
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article
Spatial memory dissociations in mice lacking GluR1
D. Reisel, D. M. Bannerman, W. B. Schmitt, R. M. J. Deacon, J. Flint, T. Borchardt, P. H. Seeburg and J. N. P. Rawlins
Nature Neuroscience 5, 868–873
(September 2002); doi:10.1038/nn910
| Abstract | Full Text (HTML/PDF) |
review article
Is there more to GABA than synaptic inhibition?
David F. Owens and Arnold R. Kriegstein
Nature Reviews Neuroscience 3, 715–727
(September 2002); doi:10.1038/nrn919
| Summary | Full Text (HTML / PDF) |
review article
Why does remyelination fail in multiple sclerosis?
Robin J. M. Franklin
Nature Reviews Neuroscience 3, 705–714
(September 2002); doi:10.1038/nrn917
| Summary | Full Text (HTML / PDF) |
review article
Phosphodiesterase 5 inhibitors: current status and potential applications
David P. Rotella
Nature Reviews Drug Discovery 1, 674–682
(September 2002); doi:10.1038/nrd893
| Summary | Full Text (HTML / PDF) |
article
Structure of the Sec23/24-Sar1 pre-budding complex of the COPII vesicle coat
Xiping Bi, Richard A. Corpina and Jonathan Goldberg
Nature 419, 271–277
(19 September 2002); doi:10.1038/nature01040
| Summary | Full Text (HTML / PDF) |
letters to nature
Robustness of the BMP morphogen gradient in Drosophila embryonic patterning
Avigdor Eldar, Ruslan Dorfman, Daniel Weiss, Hilary Ashe, Ben-Zion Shilo and Naama Barkai
Nature 419, 304–308
(19 September 2002); doi:10.1038/nature01061
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news and views
Developmental biology: Sharp peaks from shallow sources
Hans Meinhardt and Siegfried Roth
Nature 419, 261–262
(19 September 2002); doi:10.1038/419261a
| Full Text (HTML / PDF) |
letters to nature
Forkhead transcription factor FOXO3a protects quiescent cells from oxidative stress
Geert J. P. L. Kops, Tobias B. Dansen, Paulien E. Polderman, Ingrid Saarloos, Karel W. A. Wirtz, Paul J. Coffer, Ting-T. Huang, Johannes L. Bos, René H. Medema and Boudewijn M. T. Burgering
Nature 419, 316–321
(19 September 2002); doi:10.1038/nature01036
| First Paragraph | Full Text (HTML / PDF) |
article
Microscopic analysis of polymerization dynamics with individual actin filaments
Ikuko Fujiwara, Shin Takahashi, Hisashi Tadakuma, Takashi Funatsu and Shin'ichi Ishiwata
Nature Cell Biology 4, 666–673
(September 2002); doi:10.1038/ncb841
| Abstract | Full Text (HTML/PDF) |
news and views
A minor actin catastrophe
Ryan Littlefield and Velia M. Fowler
Nature Cell Biology 4, E209
(September 2002); doi:10.1038/ncb0902-e209
| Full Text (HTML/PDF) |
brief communication
MOR1/GEM1 has an essential role in the plant-specific cytokinetic phragmoplast
David Twell, Soon Ki Park, Timothy J. Hawkins, Daniel Schubert, Renate Schmidt, Andrei Smertenko and Patrick J. Hussey
Nature Cell Biology 4, 711–714
(September 2002); doi:10.1038/ncb844
| First Paragraph | Full Text (HTML/PDF) |
brief communication
The Semaphorin 4D receptor controls invasive growth by coupling with Met
Silvia Giordano, Simona Corso, Paolo Conrotto, Stefania Artigiani, Giorgio Gilestro, Davide Barberis, Luca Tamagnone and Paolo M. Comoglio
Nature Cell Biology 4, 720–724
(September 2002); doi:10.1038/ncb843
| First Paragraph | Full Text (HTML/PDF) |
review article
g-Secretase-mediated proteolysis in cell-surface-receptor signalling
Mark E. Fortini
Nature Reviews Molecular Cell Biology 3, 673–684
(September 2002); doi:10.1038/nrm910
| Summary | Full Text (HTML / PDF) |
review article
Listening in on bacteria: acyl-homoserine lactone signalling
Clay Fuqua and E. Peter Greenberg
Nature Reviews Molecular Cell Biology 3, 685–695
(September 2002); doi:10.1038/nrm907
| Summary | Full Text (HTML / PDF) |
perspectives
Signalling shortcuts: cell-surface receptors in the nucleus?
Alan Wells and Ulrich Marti
Nature Reviews Molecular Cell Biology 3, 697–702
(September 2002); doi:10.1038/nrm905
| Summary | Full Text (HTML / PDF) |
article
Sensitization of IFN-g Jak-STAT signaling during macrophage activation
Xiaoyu Hu, Carmen Herrero, Wai-Ping Li, Taras T. Antoniv, Erik Falck-Pedersen, Alisa E. Koch, James M. Woods, G. Kenneth Haines and III Lionel B. Ivashkiv
Nature Immunology 3, 859–866
(September 2002); doi:10.1038/ni828
| Abstract | Full Text (HTML/PDF) |
article
DCs induce CD40-independent immunoglobulin class switching through BLyS and APRIL
Mikhail B. Litinskiy, Bernardetta Nardelli, David M. Hilbert, Bing He, Andras Schaffer, Paolo Casali and Andrea Cerutti
Nature Immunology 3, 822–829
(September 2002); doi:10.1038/ni829
| Abstract | Full Text (HTML/PDF) |
news and views
BLySsful interactions between DCs and B cells
Andrew J. Macpherson and Alain Lamarre
Nature Immunology 3, 798–800
(September 2002); doi:10.1038/ni0902-798
| Full Text (HTML/PDF) |
review article
Coeliac disease: dissecting a complex inflammatory disorder
Ludvig M. Sollid
Nature Reviews Immunology 2, 647–655
(September 2002); doi:10.1038/nri885
| Summary | Full Text (HTML / PDF) |
article
Blockage of Ca2+-permeable AMPA receptors suppresses migration and induces apoptosis in human glioblastoma cells
Shogo Ishiuchi, Keisuke Tsuzuki, Yukari Yoshida, Nobuaki Yamada, Norikazu Hagimura, Haruo Okado, Akiko Miwa, Hideyuki Kurihara, Yoichi Nakazato, Masaru Tamura, Tomio Sasaki and Seiji Ozawa
Nature Medicine 8, 971–978
(September 2002); doi:10.1038/nm746
| Abstract | Full Text (HTML/PDF) |
news and views
Paving new pathways
Jeffrey D. Rothstein
Nature Medicine 8, 938–940
(September 2002); doi:10.1038/nm0902-938
| Full Text (HTML/PDF) |
article
Antigen-specific regulatory T cells develop via the ICOS-ICOS-ligand pathway and inhibit allergen-induced airway hyperreactivity
Omid Akbari, Gordon J. Freeman, Everett H. Meyer, Edward A. Greenfield, Tammy T. Chang, Arlene H. Sharpe, Gerald Berry, Rosemarie H. DeKruyff and Dale T. Umetsu
Nature Medicine 8, 1024–1032
(September 2002); doi:10.1038/nm745
| Abstract | Full Text (HTML/PDF) |
commentary
Endocrine gland-derived VEGF and the emerging hypothesis of organ-specific regulation of angiogenesis
Jennifer LeCouter, Rui Lin and Napoleone Ferrara
Nature Medicine 8, 913–917
(September 2002); doi:10.1038/nm0902-913
| Full Text (HTML/PDF) |
letter
Distinct in vivo requirements for establishment versus maintenance of transcriptional repression
John C. Wheeler, Christine VanderZwan, Xiaoti Xu, Deborah Swantek, W. Daniel Tracey and J. Peter Gergen
Nature Genetics 32, 206–210
(September 2002); doi:10.1038/ng942
| First Paragraph | Full Text (HTML/PDF) |
news and views
Stopping transcription in its tracks
Barbara Jennings
Nature Genetics 32, 87–88
(September 2002); doi:10.1038/ng943
| Full Text (HTML/PDF) |
review article
Arteries and veins: making a difference with zebrafish
Nathan D. Lawson and Brant M. Weinstein
Nature Reviews Genetics 3, 674–682
(September 2002); doi:10.1038/nrg888
| Summary | Full Text (HTML / PDF) |
brief communication
Differential regulation of synaptic and extra-synaptic NMDA receptors
Bo Li, Nansheng Chen, Tao Luo, Yo Otsu, Timothy H. Murphy and Lynn A. Raymond
Nature Neuroscience 5, 833–834
(September 2002); doi:10.1038/nn912
| First Paragraph | Full Text (HTML/PDF) |
article
Altered urinary bladder function in mice lacking the vanilloid receptor TRPV1
L.A. Birder, Y. Nakamura, S. Kiss, M.L. Nealen, S. Barrick, A.J. Kanai, E. Wang, G. Ruiz, W.C. de Groat, G. Apodaca, S. Watkins and M.J. Caterina
Nature Neuroscience 5, 856–860
(September 2002); doi:10.1038/nn902
| Abstract | Full Text (HTML/PDF) |
review article
Excitatory actions of GABA during development: the nature of the nurture
Yehezkel Ben-Ari
Nature Reviews Neuroscience 3, 728–739
(September 2002); doi:10.1038/nrn920
| Summary | Full Text (HTML / PDF) |
review article
Clinical proteomics: translating benchside promise into bedside reality
Emanuel F. Petricoin, Kathryn C. Zoon, Elise C. Kohn, J. Carl Barrett and Lance A. Liotta
Nature Reviews Drug Discovery 1, 683–695
(September 2002); doi:10.1038/nrd891
| Summary | Full Text (HTML / PDF) |
review article
Protein tyrosine phosphatase 1B inhibitors for diabetes
Theodore O. Johnson, Jacques Ermolieff and Michael R. Jirousek
Nature Reviews Drug Discovery 1, 696–709
(September 2002); doi:10.1038/nrd895
| Summary | Full Text (HTML / PDF) |
article
RAD6-dependent DNA repair is linked to modification of PCNA by ubiquitin and SUMO
Carsten Hoege, Boris Pfander, George-Lucian Moldovan, George Pyrowolakis and Stefan Jentsch
Nature 419, 135–141
(12 September 2002); doi:10.1038/nature00991
| Summary | Full Text (HTML / PDF) |
news and views
DNA repair: Right on target with ubiquitin
Cecile M. Pickart Cellular DNA-repair mechanisms prevent mutations from accumulating, thereby averting defects in cell function. A molecule best known for its role in protein degradation is now shown to have a specific task in DNA repair.
Nature 419, 120–121
(12 September 2002); doi:10.1038/419120a
| Full Text (HTML / PDF) |
letters to nature
Loss of the Lkb1 tumour suppressor provokes intestinal polyposis but resistance to transformation
Nabeel Bardeesy, Manisha Sinha, Aram F. Hezel, Sabina Signoretti, Nathaniel A. Hathaway, Norman E. Sharpless, Massimo Loda, Daniel R. Carrasco and Ronald A. DePinho
Nature 419, 162–167
(12 September 2002); doi:10.1038/nature01045
| First Paragraph | Full Text (HTML / PDF) |
news and views
Cancer: Stuck at first base
Louise van der Weyden, Jos Jonkers and Allan Bradley
Nature 419, 127–128
(12 September 2002); doi:10.1038/419127a
| Full Text (HTML/PDF) |
letters to nature
SINAT5 promotes ubiquitin-related degradation of NAC1 to attenuate auxin signals
Qi Xie, Hui-Shan Guo, Geza Dallman, Shengyun Fang, Allan M. Weissman and Nam-Hai Chua
Nature 419, 167–170
(12 September 2002); doi:10.1038/nature00998
| First Paragraph | Full Text (HTML/PDF) |
article
Zizimin1, a novel Cdc42 activator, reveals a new GEF domain for Rho proteins
Nahum Meller, Mohammad Irani-Tehrani, William B. Kiosses, Miguel A. Del Pozo and Martin A. Schwartz
Nature Cell Biology 4, 639–647
(September 2002); doi:10.1038/ncb835
| Abstract | Full Text (HTML/PDF) |
brief communication
Proteasome subunit Rpn1 binds ubiquitin-like protein domains
Suzanne Elsasser, Rayappa R. Gali, Martin Schwickart, Christopher N. Larsen, David S. Leggett, Britta Müller, Matthew T. Feng, Fabian Tübing, Gunnar A.G. Dittmar and Daniel Finley
Nature Cell Biology 4, 725–730
(September 2002); doi:10.1038/ncb845
| First Paragraph | Full Text (HTML/PDF) |
review article
Signalling: Mixed-lineage kinase control of JNK and p38 MAPK pathways
Kathleen A. Gallo and Gary L. Johnson
Nature Reviews Molecular Cell Biology 3, 663–672
(September 2002); doi:10.1038/nrm906
| Abstract | Full Text (HTML/PDF) |
perspectives
Timeline: Signalling through nuclear receptors
Jamshed R. Tata
Nature Reviews Molecular Cell Biology 3, 702–710
(September 2002); doi:10.1038/nrm914
| Abstract | Full Text (HTML/PDF) |
article
A requirement for CARMA1 in TCR-induced NF-kB activation
Donghai Wang, Yun You, Sara M. Case, Linda M. McAllister-Lucas, Lin Wang, Peter S. DiStefano, Gabriel Nuñez, John Bertin and Xin Lin
Nature Immunology 3, 830–835
(September 2002); doi:10.1038/ni824
| Abstract | Full Text (HTML/PDF) |
article
CARMA1 is a critical lipid raft-associated regulator of TCR-induced NF-kB activation
Olivier Gaide, Benoît Favier, Daniel F. Legler, David Bonnet, Brian Brissoni, Salvatore Valitutti, Claude Bron, Jürg Tschopp and Margot Thome
Nature Immunology 3, 836–843
(September 2002); doi:10.1038/ni830
| Abstract | Full Text (HTML/PDF) |
news and views
Up the down staircase
David Wallach
Nature Immunology 3, 802–803
(September 2002); doi:10.1038/ni0902-802
| Full Text (HTML/PDF) |
review article
Nf-kb, chemokine gene transcription and tumour growth
Ann Richmond
Nature Reviews Immunology 2, 664–674
(September 2002); doi:10.1038/nri887
| Abstract | Full Text (HTML/PDF) |
article
Activation of Notch-1 signaling maintains the neoplastic phenotype in human Ras-transformed cells
Sanne Weijzen, Paola Rizzo, Mike Braid, Radhika Vaishnav, Suzanne M. Jonkheer, Andrei Zlobin, Barbara A. Osborne, Sridevi Gottipati, Jon C. Aster, William C. Hahn, Michael Rudolf, Kalliopi Siziopikou, W. Martin Kast and Lucio Miele
Nature Medicine 8, 979–986
(September 2002); doi:10.1038/nm754
| Abstract | Full Text (HTML/PDF) |
article
Lethal H5N1 influenza viruses escape host anti-viral cytokine responses
Sang Heui Seo, Erich Hoffmann and Robert G. Webster
Nature Medicine 8, 950–954
(September 2002); doi:10.1038/nm757
| Abstract | Full Text (HTML/PDF) |
news and views
The makings of a killer
Peter Palese, Christopher F. Basler and Adolfo García-Sastre
Nature Medicine 8, 927–928
(September 2002); doi:10.1038/nm0902-927
| Full Text (HTML/PDF) |
review article
Molecular basis of the VHL hereditary cancer syndrome
William G. Kaelin Jr
Nature Reviews Cancer 2, 673–682
(September 2002); doi:10.1038/nrc885
| Abstract | Full Text (HTML/PDF) |
letter
Genome-wide retroviral insertional tagging of genes involved in cancer in Cdkn2a-deficient mice
Anders H. Lund, Geoffrey Turner, Alla Trubetskoy, Els Verhoeven, Ellen Wientjens, Danielle Hulsman, Robert Russell, Ronald A. DePinho, Jack Lenz and Maarten van Lohuizen
Nature Genetics 32, 160–165
(September 2002); doi:10.1038/ng956
| First Paragraph | Full Text (HTML/PDF) |
progress
Genetics, cytokines and human infectious disease: lessons from weakly pathogenic mycobacteria and salmonellae
Tom H.M. Ottenhoff, Frank A.W. Verreck, Elgin G.R. Lichtenauer-Kaligis, Marieke A. Hoeve, Ozden Sanal and Jaap T. van Dissel
Nature Genetics 32, 97–105
(September 2002); doi:10.1038/ng0902-97
| Abstract | Full Text (HTML/PDF) |
article
Presenilins are not required for Ab42 production in the early secretory pathway
Christina A. Wilson, Robert W. Doms, Hui Zheng and Virginia M.-Y. Lee
Nature Neuroscience 5, 849–855
(September 2002); doi:10.1038/nn898
| Abstract | Full Text (HTML/PDF) |
brief communication
Development of normal retinal organization depends on Sonic hedgehog signaling from ganglion cells
Ya Ping Wang, Gabriel Dakubo, Paul Howley, Katrina D. Campsall, Chantal J. Mazarolle, Sarah A. Shiga, Paula M. Lewis, Andrew P. McMahon and Valerie A. Wallace
Nature Neuroscience 5, 831–832
(September 2002); doi:10.1038/nn911
| First Paragraph | Full Text (HTML/PDF) |
review article
Breaking the neuronal sphere: regulation of the actin cytoskeleton in neuritogenesis
Jorge Santos Da Silva and Carlos G. Dotti
Nature Reviews Neuroscience 3, 694–704
(September 2002); doi:10.1038/nrn918
| Abstract | Full Text (HTML/PDF) |
news and views
A P-type ion pump at work
C. Roy D. Lancaster
Nature Structural Biology 9, 643–645
(September 2002); doi:10.1038/nsb0902-643
| Full Text (HTML/PDF) |
original paper
XIAP inhibition of caspase-3 preserves its association with the Apaf-1 apoptosome and prevents CD95- and Bax-induced apoptosis
S B Bratton, J Lewis, M Butterworth, C S Duckett & G M Cohen
Cell Death and Differentiation 9, 881–892
(September 2002); doi:10.1038/sj.cdd.4401069
| Abstract |
original paper
Cellular transformation by a FERM domain mutant of the Nf2 tumor suppressor gene
Kristen C Johnson, Joseph L Kissil, Jessica L Fry & Tyler Jacks
Oncogene 21, 5990–5997
(5 September 2002); doi:10.1038/sj.onc.1205693
| Abstract |
article
Altering the pathway of immunoglobulin hypermutation by inhibiting uracil-DNA glycosylase
Javier Di Noia and Michael S. Neuberger
Nature 419, 43–48
(05 September 2002); doi:10.1038/nature00981
| Summary | Full Text (HTML / PDF) |
news and views
Immunology: The roots of antibody diversity
Patricia J. Gearhart
Nature 419, 29–31
(05 September 2002); doi:10.1038/419029a
| Full Text (HTML / PDF) |
letters to nature
Protective role of phospholipid oxidation products in endotoxin-induced tissue damage
Valery N. Bochkov, Alexandra Kadl, Joakim Huber, Florian Gruber, Bernd R. Binder and Norbert Leitinger
Nature 419, 77–81
(05 September 2002); doi:10.1038/nature01023
| First Paragraph | Full Text (HTML / PDF) |
letters to nature
Actin dynamics in the contractile ring during cytokinesis in fission yeast
Robert J. Pelham Jr and Fred Chang
Nature 419, 82–86
(05 September 2002); doi:10.1038/nature00999
| First Paragraph | Full Text (HTML / PDF) |
news and views
Cell biology: Spinning actin to divide
Shuh Narumiya and Issei Mabuchi
Nature 419, 27–28
(05 September 2002); doi:10.1038/419027a
| Full Text (HTML / PDF) |
letters to nature
RNA aptamers as reversible antagonists of coagulation factor IXa
Christopher P. Rusconi, Elizabeth Scardino, Juliana Layzer, George A. Pitoc, Thomas L. Ortel, Dougald Monroe and Bruce A. Sullenger
Nature 419, 90–94
(05 September 2002); doi:10.1038/nature00963
| First Paragraph | Full Text (HTML / PDF) |
news and views
Medicine: RNA as drug and antidote
Edward Tuddenham
Nature 419, 23–24
(05 September 2002); doi:10.1038/419023a
| Full Text (HTML / PDF) |
review article
The voltage-gated potassium channels and their relatives
Gary Yellen
Nature 419, 35–42
(05 September 2002); doi:10.1038/nature00978
| Summary | Full Text (HTML / PDF) |
article
TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling
Ken Inoki, Yong Li, Tianquan Zhu, Jun Wu and Kun-Liang Guan
Nature Cell Biology 4, 648–657
(September 2002); doi:10.1038/ncb839
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article
Akt regulates growth by directly phosphorylating Tsc2
Christopher J. Potter, Laura G. Pedraza and Tian Xu
Nature Cell Biology 4, 658–665
(September 2002); doi:10.1038/ncb840
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brief communication
Tsc tumour suppressor proteins antagonize amino-acid-TOR signalling
Xinsheng Gao, Yong Zhang, Peter Arrazola, Okio Hino, Toshiyuki Kobayashi, Raymond S. Yeung, Binggeng Ru and Duojia Pan
Nature Cell Biology 4, 699–704
(September 2002); doi:10.1038/ncb847
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news and views
TSC1-TSC2: a complex tale of PKB-mediated S6K regulation
Edward J. McManus and Dario R. Alessi
Nature Cell Biology 4, E214
(September 2002); doi:10.1038/ncb0902-e214
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brief communication
Reaper-mediated inhibition of DIAP1-induced DTRAF1 degradation results in activation of JNK in Drosophila
Erina Kuranaga, Hirotaka Kanuka, Tatsushi Igaki, Kazunobu Sawamoto, Hidenori Ichijo, Hideyuki Okano and Masayuki Miura
Nature Cell Biology 4, 705–710
(September 2002); doi:10.1038/ncb842
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review article
Signalling: Seven-transmembrane receptors
Kristen L. Pierce, Richard T. Premont and Robert J. Lefkowitz
Nature Reviews Molecular Cell Biology 3, 639–650
(September 2002); doi:10.1038/nrm908
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article
PI3K-mediated negative feedback regulation of IL-12 production in DCs
Taro Fukao, Masanobu Tanabe, Yasuo Terauchi, Takayuki Ota, Satoshi Matsuda, Tomoichiro Asano, Takashi Kadowaki, Tsutomu Takeuchi and Shigeo Koyasu
Nature Immunology 3, 875–881
(September 2002); doi:10.1038/ni825
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article
Cross-primed CD8+ T cells mediate graft rejection via a distinct effector pathway
Anna Valujskikh, Olivier Lantz, Susanna Celli, Polly Matzinger and Peter S. Heeger
Nature Immunology 3, 844–851
(September 2002); doi:10.1038/ni831
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news and views
Transplantation—caught in the crossfire!
Herman Waldmann
Nature Immunology 3, 803–804
(September 2002); doi:10.1038/ni0902-803
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review article
Viruses and interferon: A fight for supremacy
Michael G. Katze, Yupeng He and Michael Gale Jr
Nature Reviews Immunology 2, 675–687
(September 2002); doi:10.1038/nri888
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article
Parathyroid hormone-related peptide is a naturally occurring, protein kinase A-dependent angiogenesis inhibitor
Manjiri M. Bakre, Yuhong Zhu, Hong Yin, Doug W. Burton, Robert Terkeltaub, Leonard J. Deftos and Judith A. Varner
Nature Medicine 8, 995–1003
(September 2002); doi:10.1038/nm753
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article
Inhibitor of apoptosis protein survivin regulates vascular injury
Olivier P. Blanc-Brude, Jun Yu, Hector Simosa, Michael S. Conte, William C. Sessa and Dario C. Altieri
Nature Medicine 8, 987–994
(September 2002); doi:10.1038/nm750
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review article
Strategies for mmp inhibition in cancer: innovations for the post-trial era
Christopher Mark Overall and Carlos López-Otín
Nature Reviews Cancer 2, 657–672
(September 2002); doi:10.1038/nrc884
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letter
High-throughput retroviral tagging to identify components of specific signaling pathways in cancer
Harald Mikkers, John Allen, Puck Knipscheer, Lieke Romeyn, Augustinus Hart, Edwin Vink and Anton Berns
Nature Genetics 32, 153–159
(September 2002); doi:10.1038/ng950
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article
Nerve growth cone guidance mediated by G protein-coupled receptors
Yang Xiang, Yan Li, Zhe Zhang, Kai Cui, Sheng Wang, Xiao-bing Yuan, Chien-ping Wu, Mu-ming Poo and Shumin Duan
Nature Neuroscience 5, 843–848
(September 2002); doi:10.1038/nn899
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brief communication
Phosphatidylinositol 3 kinase regulates synapse specificity of hippocampal long-term depression
Michael I. Daw, Zuner A. Bortolotto, Emilia Saulle, Shahid Zaman, Graham L. Collingridge and John T.R. Isaac
Nature Neuroscience 5, 835–836
(September 2002); doi:10.1038/nn903
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perspectives
Opinion: Beyond the role of glutamate as a neurotransmitter
Maiken Nedergaard, Takahiro Takano and Anker J. Hansen
Nature Reviews Neuroscience 3, 748–755
(September 2002); doi:10.1038/nrn916
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research article
Inhibition of glioma growth by tumor-specific activation of double-stranded RNA-dependent protein kinase PKR
Alexei Shir and Alexander Levitzki
Nature Biotechnology 20, 895–900
(September 2002); doi:10.1038/nbt730
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news and views
Chaperones and transcriptional regulation by nuclear receptors
Jason C. Young and F. Ulrich Hartl
Nature Structural Biology 9, 640–642
(September 2002); doi:10.1038/nsb0902-640
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