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The Research Library categorizes, and provides access to, all recent signaling-related research published in the Nature Publishing Group journals. The selection is deliberately broad to facilitate access to all research impacting on the signaling community. Both primary research and review articles are included, as are 'News and Views' articles.
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letters to nature
Multiple forms of synaptic plasticity triggered by selective suppression of activity in individual neurons
Juan Burrone, Michael O'Byrne and Venkatesh N. Murthy
Nature 420, 414–418
(28 November 2002); doi:10.1038/nature01242
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letters to nature
Functional improvement of dystrophic muscle by myostatin blockade
Sasha Bogdanovich, Thomas O. B. Krag, Elisabeth R. Barton, Linda D. Morris, Lisa-Anne Whittemore, Rexford S. Ahima and Tejvir S. Khurana
Nature 420, 418–421
(28 November 2002); doi:10.1038/nature01154
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letters to nature
Shoot control of root development and nodulation is mediated by a receptor-like kinase
Lene Krusell, Lene H. Madsen, Shusei Sato, Grégoire Aubert, Aratz Genua, Krzysztof Szczyglowski, Gérard Duc, Takakazu Kaneko, Satoshi Tabata, Frans de Bruijn, Eloisa Pajuelo, Niels Sandal and Jens Stougaard
Nature 420, 422–426
(28 November 2002); doi:10.1038/nature01207
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letters to nature
HAR1 mediates systemic regulation of symbiotic organ development
Rieko Nishimura , Masaki Hayashi, Guo-Jiang Wu , Hiroshi Kouchi, Haruko Imaizumi-Anraku, Yasuhiro Murakami, Shinji Kawasaki, Shoichiro Akao, Masayuki Ohmori, Mamoru Nagasawa, Kyuya Harada and Masayoshi Kawaguchi
Nature 420, 426–429
(28 November 2002); doi:10.1038/nature01231
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news and views
Plant biology: Fixation with regulation
J. Allan Downie and Martin Parniske
Nature 420, 369–370
(28 November 2002); doi:10.1038/420369a
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letters to nature
Self-recognition promotes the foreign antigen sensitivity of naive T lymphocytes
Irena š
Nature 420, 429–434
(28 November 2002); doi:10.1038/nature01146
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letters to nature
TRF2 associates with DREF and directs promoter-selective gene expression in Drosophila
Andreas Hochheimer, Sharleen Zhou, Shuang Zheng, Michael C. Holmes and Robert Tjian
Nature 420, 439–445
(28 November 2002); doi:10.1038/nature01167
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news and views
Circadian rhythms: The cancer connection
Michael Rosbash and Joseph S. Takahashi
Nature 420, 373–374
(28 November 2002); doi:10.1038/420373a
| Full Text (HTML / PDF) |
article
BID regulation by p53 contributes to chemosensitivity
Joanna K. Sax, Peiwen Fei, Maureen E. Murphy, Eric Bernhard, Stanley J. Korsmeyer and Wafik S. El-Deiry
Nature Cell Biology 4, 842–849
(November 2002); doi:10.1038/ncb866
| Abstract | Full Text (HTML/PDF) |
article
Direct coupling of the cell cycle and cell death machinery by E2F
Zaher Nahle, Julia Polakoff, Ramana V. Davuluri, Mila E. McCurrach, Matthew D. Jacobson, Masashi Narita, Michael Q. Zhang, Yuri Lazebnik, Dafna Bar-Sagi and Scott W. Lowe
Nature Cell Biology 4, 859–864
(November 2002); doi:10.1038/ncb868
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brief communication
Membrane microviscosity regulates endothelial cell motility
Prabar K. Ghosh, Amit Vasanji, Gurunathan Murugesan, Steven J. Eppell, Linda M. Graham and Paul L. Fox
Nature Cell Biology 4, 894–900
(November 2002); doi:10.1038/ncb873
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meeting report
Hopeful monsters and morphogens at the beach
Lee Niswander and Kathryn V. Anderson
Nature Cell Biology 4, E259
(November 2002); doi:10.1038/ncb1102-e259
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article
HIV-specific CD8+ T cell proliferation is coupled to perforin expression and is maintained in nonprogressors
Stephen A. Migueles, Alisha C. Laborico, W. Lesley Shupert, M. Shirin Sabbaghian, Ronald Rabin, Claire W. Hallahan, Debbie Van Baarle, Stefan Kostense, Frank Miedema, Mary McLaughlin, Linda Ehler, Julia Metcalf, Shuying Liu and Mark Connors
Nature Immunology 3, 1061–1068
(November 2002); doi:10.1038/ni845
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review article
Natural selection of tumor variants in the generation of “tumor escape” phenotypes
Hung T. Khong and Nicholas P. Restifo
Nature Immunology 3, 999–1005
(November 2002); doi:10.1038/ni1102-999
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review article
Viral interference with antigen presentation
Jonathan W. Yewdell and Ann B. Hill
Nature Immunology 3, 1019–1025
(November 2002); doi:10.1038/ni1102-1019
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review article
Bacterial strategies for overcoming host innate and adaptive immune responses
Mathias W. Hornef, Mary Jo Wick, Mikael Rhen and Staffan Normark
Nature Immunology 3, 1033–1040
(November 2002); doi:10.1038/ni1102-1033
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review article
Platelets in atherothrombosis
Zaverio M. Ruggeri
Nature Medicine 8, 1227–1234
(November 2002); doi:10.1038/nm1102-1227
| Abstract | Full Text (HTML/PDF) |
perspectives
Timeline: A fortunate choice: the history of Arabidopsis as a model plant
Chris Somerville and Maarten Koornneef
Nature Reviews Genetics 3, 883–889
(November 2002); doi:10.1038/nrg927
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article
Suppressor of cytokine signaling 2 regulates neuronal differentiation by inhibiting growth hormone signaling
Ann M. Turnley, Clare H. Faux, Rodney L. Rietze, Jason R. Coonan and Perry F. Bartlett
Nature Neuroscience 5, 1155–1162
(November 2002); doi:10.1038/nn954
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article
A transient receptor potential channel expressed in taste receptor cells
Cristian A. Pérez, Liquan Huang, Minqing Rong, J. Ashot Kozak, Axel K. Preuss, Hailin Zhang, Marianna Max and Robert F. Margolskee
Nature Neuroscience 5, 1169–1176
(November 2002); doi:10.1038/nn952
| Abstract | Full Text (HTML/PDF) |
review
Neuroprotective and neurorestorative strategies for Parkinson's disease
Ted M. Dawson and Valina L. Dawson
Nature Neuroscience 5, 1058–1061
(November 2002); doi:10.1038/nn941
| Abstract | Full Text (HTML/PDF) |
review article
Calcium dyshomeostasis and intracellular signalling in alzheimer's disease
Frank M. LaFerla
Nature Reviews Neuroscience 3, 862–872
(November 2002); doi:10.1038/nrn960
| Summary | Full Text (HTML / PDF) |
review article
Hepatitis C therapeutics: current status and emerging strategies
Seng-Lai Tan, Arnim Pause, Yuguang Shi and Nahum Sonenberg
Nature Reviews Drug Discovery 1, 867–881
(November 2002); doi:10.1038/nrd937
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article
Insights into DNA recombination from the structure of a RAD51-BRCA2 complex
Luca Pellegrini, David S. Yu, Thomas Lo, Shubha Anand, MiYoung Lee, Tom L. Blundell and Ashok R. Venkitaraman
Nature 420, 287–293
(21 November 2002); doi:10.1038/nature01230
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letters to nature
Essential role for TIRAP in activation of the signalling cascade shared by TLR2 and TLR4
Masahiro Yamamoto, Shintaro Sato, Hiroaki Hemmi, Hideki Sanjo, Satoshi Uematsu, Tsuneyasu Kaisho , Katsuaki Hoshino, Osamu Takeuchi, Masaya Kobayashi, Takashi Fujita, Kiyoshi Takeda and Shizuo Akira
Nature 420, 324–329
(21 November 2002); doi:10.1038/nature01182
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letters to nature
The adaptor molecule TIRAP provides signalling specificity for Toll-like receptors
Tiffany Horng, Gregory M. Barton, Richard A. Flavell and Ruslan Medzhitov
Nature 420, 329–333
(21 November 2002); doi:10.1038/nature01180
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letters to nature
A central role for JNK in obesity and insulin resistance
Jiro Hirosumi, Gürol Tuncman, Lufen Chang, Cem Z. Görgün, K. Teoman Uysal, Kazuhisa Maeda, Michael Karin and Gökhan S. Hotamisligil
Nature 420, 333–336
(21 November 2002); doi:10.1038/nature01137
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news and views
Developmental biology: Colon construction
Mark Peifer
Nature 420, 274–276
(21 November 2002); doi:10.1038/420274a
| Full Text (HTML / PDF) |
news and views
Cancer: Super p53
Barbara Marte
Nature 420, 279
(21 November 2002); doi:10.1038/420279a
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article
CNS integrins switch growth factor signalling to promote target-dependent survival
Holly Colognato, Wia Baron, Virginia Avellana-Adalid, Jõao B. Relvas, Anne Baron-Van Evercooren, Elisabeth Georges-Labouesse and Charles ffrench-Constant
Nature Cell Biology 4, 833–841
(November 2002); doi:10.1038/ncb865
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news and views
Integrins as developmental switches
Trent A. Watkins and Ben A. Barres
Nature Cell Biology 4, E253
(November 2002); doi:10.1038/ncb1102-e253
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article
The Doc1 subunit is a processivity factor for the anaphase-promoting complex
Christopher W. Carroll and David O. Morgan
Nature Cell Biology 4, 880–887
(November 2002); doi:10.1038/ncb871
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article
Thymocyte expression of cathepsin L is essential for NKT cell development
Karen Honey, Kamel Benlagha, Courtney Beers, Katherine Forbush, Luc Teyton, Monique J. Kleijmeer, Alexander Y. Rudensky and Albert Bendelac
Nature Immunology 3, 1069–1074
(November 2002); doi:10.1038/ni844
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review article
To kill or be killed: viral evasion of apoptosis
Chris A. Benedict, Paula S. Norris and Carl F. Ware
Nature Immunology 3, 1013–1018
(November 2002); doi:10.1038/ni1102-1013
| Abstract | Full Text (HTML/PDF) |
review article
Evasion of innate immunity by parasitic protozoa
David Sacks and Alan Sher
Nature Immunology 3, 1041–1047
(November 2002); doi:10.1038/ni1102-1041
| Abstract | Full Text (HTML/PDF) |
article
Endogenous lipid- and peptide-derived anti-inflammatory pathways generated with glucocorticoid and aspirin treatment activate the lipoxin A4 receptor
Mauro Perretti, Nan Chiang, Mylinh La, Iolanda M. Fierro, Stefano Marullo, Stephen J Getting, Egle Solito and Charles N. Serhan
Nature Medicine 8, 1296–1302
(November 2002); doi:10.1038/nm786
| Abstract | Full Text (HTML/PDF) |
review article
Innate and acquired immunity in atherogenesis
Christoph J. Binder, Mi-Kyung Chang, Peter X. Shaw, Yury I. Miller, Karsten Hartvigsen, Asheesh Dewan and Joseph L. Witztum
Nature Medicine 8, 1218–1226
(November 2002); doi:10.1038/nm1102-1218
| Abstract | Full Text (HTML/PDF) |
review article
The macrophage foam cell as a target for therapeutic intervention
Andrew C. Li and Christopher K. Glass
Nature Medicine 8, 1235–1242
(November 2002); doi:10.1038/nm1102-1235
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article
Polarized and compartment-dependent distribution of HCN1 in pyramidal cell dendrites
Andrea Lörincz, Takuya Notomi, Gábor Tamás, Ryuichi Shigemoto and Zoltan Nusser
Nature Neuroscience 5, 1185–1193
(November 2002); doi:10.1038/nn962
| Abstract | Full Text (HTML/PDF) |
brief communication
Hippocampal CRE-mediated gene expression is required for contextual memory formation
Jaime Athos, Soren Impey, Victor V. Pineda, Xi Chen and Daniel R. Storm
Nature Neuroscience 5, 1119–1120
(November 2002); doi:10.1038/nn951
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review
Neurotrophins: from enthusiastic expectations through sobering experiences to rational therapeutic approaches
Hans Thoenen and Michael Sendtner
Nature Neuroscience 5, 1046–1050
(November 2002); doi:10.1038/nn938
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review
Can we conquer pain?
Joachim Scholz and Clifford J. Woolf
Nature Neuroscience 5, 1062–1067
(November 2002); doi:10.1038/nn942
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review article
Ubiquitin and the synapse
Ashok N. Hegde and Aaron DiAntonio
Nature Reviews Neuroscience 3, 854–861
(November 2002); doi:10.1038/nrn961
| Summary | Full Text (HTML / PDF) |
review article
Designing peptide receptor agonists and antagonists
Victor J. Hruby
Nature Reviews Drug Discovery 1, 847–858
(November 2002); doi:10.1038/nrd939
| Summary | Full Text (HTML / PDF) |
original paper
Differential roles of Ras and Rap1 in growth factor-dependent activation of phospholipase Cε
Chunhua Song, Takaya Satoh, Hironori Edamatsu, Dongmei Wu, Makoto Tadano, Xianlong Gao and Tohru Kataoka
Oncogene 21, 8105–8113
(November 2002); doi:10.1038/sj.onc.1206003
| Abstract |
original paper
Novel genes regulated by Sonic Hedgehog in pluripotent mesenchymal cells
Wendy J Ingram, Carol A Wicking, Sean M Grimmond, Alistair R Forrest and Brandon J Wainwright
Oncogene 21, 8196–8205
(November 2002); doi:10.1038/sj.onc.1205975
| Abstract |
letters to nature
The F-box protein Slimb controls the levels of clock proteins Period and Timeless
Brigitte Grima, Annie Lamouroux, Elisabeth Chélot, Christian Papin, Bernadette Limbourg-Bouchon and François Rouyer
Nature 420, 178–182
(14 November 2002); doi:10.1038/nature01122
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letters to nature
Non-redundant role of the long pentraxin PTX3 in anti-fungal innate immune response
Cecilia Garlanda, Emilio Hirsch, Silvia Bozza, Antonietta Salustri, Marika De Acetis, Rachele Nota, Alessia Maccagno, Federica Riva, Barbara Bottazzi, Giuseppe Peri, Andrea Doni, Luca Vago, Marina Botto, Rita De Santis, Paolo Carminati, Gregorio Siracusa, Fiorella Altruda, Annunciata Vecchi, Luigina Romani and Alberto Mantovani
Nature 420, 182–186
(14 November 2002); doi:10.1038/nature01195
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letters to nature
The heteromeric cyclic nucleotide-gated channel adopts a 3A:1B stoichiometry
Haining Zhong, Laurie L. Molday, Robert S. Molday and King-Wai Yau
Nature 420, 193–198
(14 November 2002); doi:10.1038/nature01201
| First Paragraph | Full Text (HTML / PDF) |
news and views
Medicine: Lipid signals in pain control
Nicolas G. Bazan and Rod J. Flower
Nature 420, 135–138
(14 November 2002); doi:10.1038/420135a
| Full Text (HTML / PDF) |
article
Sprouty1 and Sprouty2 provide a control mechanism for the Ras/MAPK signalling pathway
Hiroshi Hanafusa, Satoru Torii, Takayuki Yasunaga and Eisuke Nishida
Nature Cell Biology 4, 850–858
(November 2002); doi:10.1038/ncb867
| Abstract | Full Text (HTML/PDF) |
article
PML-dependent apoptosis after DNA damage is regulated by the checkpoint kinase hCds1/Chk2
Shutong Yang, Christin Kuo, John E. Bisi and Myung K. Kim
Nature Cell Biology 4, 865–870
(November 2002); doi:10.1038/ncb869
| Abstract | Full Text (HTML/PDF) |
news and views
Chk2 leaves the PML depot
Monica Venere, Tamara A. Mochan and Thanos D. Halazonetis
Nature Cell Biology 4, E255
(November 2002); doi:10.1038/ncb1102-e255
| Full Text (HTML/PDF) |
article
Wnt glycoproteins regulate the expression of FoxN1, the gene defective in nude mice
Gina Balciunaite, Marcel P. Keller, Egle Balciunaite, Luca Piali, Saulius Zuklys, Yves D. Mathieu, Jason Gill, Richard Boyd, Daniel J. Sussman and Georg A. Holländer
Nature Immunology 3, 1102–1108
(November 2002); doi:10.1038/ni850
| Abstract | Full Text (HTML/PDF) |
review article
Cancer immunoediting: from immunosurveillance to tumor escape
Gavin P. Dunn, Allen T. Bruce, Hiroaki Ikeda, Lloyd J. Old and Robert D. Schreiber
Nature Immunology 3, 991–998
(November 2002); doi:10.1038/ni1102-991
| Abstract | Full Text (HTML/PDF) |
review article
Viral evasion of natural killer cells
Jordan S. Orange, Marlys S. Fassett, Louise A. Koopman, Jonathan E. Boyson and Jack L. Strominger
Nature Immunology 3, 1006–1012
(November 2002); doi:10.1038/ni1102-1006
| Abstract | Full Text (HTML/PDF) |
review article
Chronic bacterial infections: living with unwanted guests
Douglas Young, Tracy Hussell and Gordon Dougan
Nature Immunology 3, 1026–1032
(November 2002); doi:10.1038/ni1102-1026
| Abstract | Full Text (HTML/PDF) |
review article
The immunology of susceptibility and resistance to leishmania major in mice
David Sacks and Nancy Noben-Trauth
Nature Reviews Immunology 2, 845–858
(November 2002); doi:10.1038/nri933
| Summary | Full Text (HTML / PDF) |
article
Synergism between INK4a/ARF inactivation and aberrant HGF/SF signaling in rhabdomyosarcomagenesis
Richard Sharp, Juan A. Recio, Chamelli Jhappan, Toshiyuki Otsuka, Shiquan Liu, Yanlin Yu, Wenjing Liu, Miriam Anver, Fariba Navid, Lee J. Helman, Ronald A. DePinho and Glenn Merlino
Nature Medicine 8, 1276–1280
(November 2002); doi:10.1038/nm787
| Abstract | Full Text (HTML/PDF) |
news and views
Muscling in on rhabdomyosarcoma
Webster K. Cavenee
Nature Medicine 8, 1200–1201
(November 2002); doi:10.1038/nm1102-1200
| Full Text (HTML/PDF) |
article
Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase
T. Yamauchi, J. Kamon, Y. Minokoshi, Y. Ito, H. Waki, S. Uchida, S. Yamashita, M. Noda, S. Kita, K. Ueki, K. Eto, Y. Akanuma, P. Froguel, F. Foufelle, P. Ferre, D. Carling, S. Kimura, R. Nagai, B.B. Kahn and T. Kadowaki
Nature Medicine 8, 1288–1295
(November 2002); doi:10.1038/nm788
| Abstract | Full Text (HTML/PDF) |
brief communication
Frequent somatic mutations in PTEN and TP53 are mutually exclusive in the stroma of breast carcinomas
Keisuke Kurose, Kristie Gilley, Satoshi Matsumoto, Peter H. Watson, Xiao-Ping Zhou and Charis Eng
Nature Genetics 32, 355–357
(November 2002); doi:10.1038/ng1013
| First Paragraph | Full Text (HTML/PDF) |
article
Shared receptors in axon guidance: SAX-3/Robo signals via UNC-34/Enabled and a Netrin-independent UNC-40/DCC function
Timothy W. Yu, Joe C. Hao, Wendell Lim, Marc Tessier-Lavigne and Cornelia I. Bargmann
Nature Neuroscience 5, 1147–1154
(November 2002); doi:10.1038/nn956
| Abstract | Full Text (HTML/PDF) |
review
NMDA receptor pathways as drug targets
John A. Kemp & Ruth M. McKernan
Nature Neuroscience 5, 1039–1042
(November 2002); doi:10.1038/nn936
| Abstract | Full Text (HTML/PDF) |
review article
The molecular organization of cerebellar long-term depression
Masao Ito
Nature Reviews Neuroscience 3, 896–902
(November 2002); doi:10.1038/nrn962
| Summary | Full Text (HTML / PDF) |
original paper
Cloning of a novel phosphotyrosine binding domain containing molecule, Odin, involved in signaling by receptor tyrosine kinases
Akhilesh Pandey, Blagoy Blagoev, Irina Kratchmarova, Minerva Fernandez, Mogens Nielsen, Troels Zakarias Kristiansen, Osamu Ohara, Alexandre V Podtelejnikov, Serge Roche, Harvey F Lodish & Matthias Mann
Oncogene 21, 8029–8036
(14 November 2002); doi:10.1038/sj.onc.1205988
| Abstract |
letters to nature
p75 interacts with the Nogo receptor as a co-receptor for Nogo, MAG and OMgp
Kevin C. Wang, Jieun A. Kim, Rajeev Sivasankaran, Rosalind Segal and Zhigang He
Nature 420, 74–78
(07 November 2002); doi:10.1038/nature01176
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letters to nature
The HMG-CoA reductase inhibitor, atorvastatin, promotes a Th2 bias and reverses paralysis in central nervous system autoimmune disease
Sawsan Youssef, Olaf Stüve, Juan C. Patarroyo, Pedro J. Ruiz, Jennifer L. Radosevich, Eun Mi Hur, Manuel Bravo, Dennis J. Mitchell, Raymond A. Sobel, Lawrence Steinman and Scott S. Zamvil
Nature 420, 78–84
(07 November 2002); doi:10.1038/nature01158
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news and views
Medicine: Tackling multiple sclerosis
Hartmut Wekerle
Nature 420, 39–40
(07 November 2002); doi:10.1038/420039a
| Full Text (HTML / PDF) |
letters to nature
Recruitment and regulation of phosphatidylinositol phosphate kinase type 1g by the FERM domain of talin
Gilbert Di Paolo, Lorenzo Pellegrini , Kresimir Letinic, Gianluca Cestra, Roberto Zoncu, Sergei Voronov, Sunghoe Chang, Jun Guo, Markus R. Wenk and Pietro De Camilli
Nature 420, 85–89
(07 November 2002); doi:10.1038/nature01147
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letters to nature
Type Ig phosphatidylinositol phosphate kinase targets and regulates focal adhesions
Kun Ling, Renee L. Doughman, Ari J. Firestone, Matthew W. Bunce and Richard A. Anderson
Nature 420, 89–93
(07 November 2002); doi:10.1038/nature01082
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letters to nature
Structure of a protein determined by solid-state magic-angle-spinning NMR spectroscopy
Federica Castellani, Barth van Rossum, Annette Diehl, Mario Schubert, Kristina Rehbein and Hartmut Oschkinat
Nature 420, 98–102
(07 November 2002); doi:10.1038/nature01070
| First Paragraph | Full Text (HTML / PDF) |
brief communication
NF-kB2 p100 is a pro-apoptotic protein with anti-oncogenic function
Yongqing Wang, Hongjuan Cui, Allen Schroering, Jane L. Ding, William S. Lane, Gaël McGill, David E. Fisher and Han-Fei Ding
Nature Cell Biology 4, 888–893
(November 2002); doi:10.1038/ncb872
| First Paragraph | Full Text (HTML/PDF) |
brief communication
Wound healing recapitulates morphogenesis in Drosophila embryos
William Wood, Antonio Jacinto, Richard Grose, Sarah Woolner, Jonathan Gale, Clive Wilson and Paul Martin
Nature Cell Biology 4, 907–912
(November 2002); doi:10.1038/ncb875
| First Paragraph | Full Text (HTML/PDF) |
news and views
Drosophila, actin and videotape — new insights in wound healing
Stéphane Noselli
Nature Cell Biology 4, E251
(November 2002); doi:10.1038/ncb1102-e251b
| Full Text (HTML/PDF) |
article
Sustained and dynamic inositol lipid metabolism inside and outside the immunological synapse
Patrick S. Costello, Maighread Gallagher and Doreen A. Cantrell
Nature Immunology 3, 1082–1089
(November 2002); doi:10.1038/ni848
| Abstract | Full Text (HTML/PDF) |
article
Imaging antigen-induced PI3K activation in T cells
Julie Harriague and Georges Bismuth
Nature Immunology 3, 1090–1096
(November 2002); doi:10.1038/ni847
| Abstract | Full Text (HTML/PDF) |
news and views
Slick signaling
Andrey S.-Y. Shaw
Nature Immunology 3, 1058–1059
(November 2002); doi:10.1038/ni1102-1058
| Full Text (HTML/PDF) |
article
Activation and function of cyclin T-Cdk9 (positive transcription elongation factor-b) in cardiac muscle-cell hypertrophy
Motoaki Sano, Maha Abdellatif, Hidemasa Oh, Min Xie, Luigi Bagella, Antonio Giordano, Lloyd H. Michael, Francesco J. DeMayo and Michael D. Schneider
Nature Medicine 8, 1310–1317
(November 2002); doi:10.1038/nm778
| Abstract | Full Text (HTML/PDF) |
news and views
Converting p53 from a killer into a healer
Andrei V. Gudkov
Nature Medicine 8, 1196–1198
(November 2002); doi:10.1038/nm1102-1196
| Full Text (HTML/PDF) |
review article
The pathogenesis of pituitary tumours
Sylvia L. Asa and Shereen Ezzat
Nature Reviews Cancer 2, 836–849
(November 2002); doi:10.1038/nrc926
| Summary | Full Text (HTML / PDF) |
article
Site-specific fluorescence reveals distinct structural changes with GABA receptor activation and antagonism
Yongchang Chang and David S. Weiss
Nature Neuroscience 5, 1163–1168
(November 2002); doi:10.1038/nn926
| Abstract | Full Text (HTML/PDF) |
review article
The neurotrophin receptor p75NTR: novel functions and implications for diseases of the nervous system
Georg Dechant and Yves-Alain Barde
Nature Neuroscience 5, 1131–1136
(November 2002); doi:10.1038/nn1102-1131
| Abstract | Full Text (HTML/PDF) |
review article
Calcium-dependent inactivation of neuronal calcium channels
Thomas Budde, Sven Meuth and Hans-Christian Pape
Nature Reviews Neuroscience 3, 873–883
(November 2002); doi:10.1038/nrn959
| Summary | Full Text (HTML / PDF) |
original paper
Regulation of the IRF-1 tumour modifier during the response to genotoxic stress involves an ATM-dependent signalling pathway
Jessica Pamment, Eleanor Ramsay, Michael Kelleher, David Dornan & Kathryn L Ball
Oncogene 21, 7776–7785
(7 November 2002); doi:10.1038/sj.onc.1205981
| Abstract |
article
Social feeding in Caenorhabditis elegans is induced by neurons that detect aversive stimuli
Mario de Bono, David M. Tobin, M. Wayne Davis, Leon Avery and Cornelia I. Bargmann
Nature 419, 899–903
(31 October 2002); doi:10.1038/nature01169
| First Paragraph | Full Text (HTML / PDF) |
letters to nature
Antagonistic pathways in neurons exposed to body fluid regulate social feeding in Caenorhabditis elegans
Juliet C. Coates and Mario de Bono
Nature 419, 925–929
(31 October 2002); doi:10.1038/nature01170
| First Paragraph | Full Text (HTML / PDF) |
news and views
Neurobiology: Social eating for stress
Marla B. Sokolowski
Nature 419, 893–894
(31 October 2002); doi:10.1038/419893a
| Full Text (HTML / PDF) |
letters to nature
Progenitor cell maintenance requires numb and numblike during mouse neurogenesis
Petur H. Petersen, Kaiyong Zou, Joseph K. Hwang, Yuh Nung Jan and Weimin Zhong
Nature 419, 929–934
(31 October 2002); doi:10.1038/nature01124
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letters to nature
N-CoR controls differentiation of neural stem cells into astrocytes
Ola Hermanson, Kristen Jepsen and Michael G. Rosenfeld
Nature 419, 934–939
(31 October 2002); doi:10.1038/nature01156
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letters to nature
Specific aspartyl and calpain proteases are required for neurodegeneration in C. elegans
Popi Syntichaki, Keli Xu, Monica Driscoll and Nektarios Tavernarakis
Nature 419, 939–944
(31 October 2002); doi:10.1038/nature01108
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letters to nature
Dual regulation of voltage-gated calcium channels by PtdIns(4,5)P2
Li Wu, Claudia S. Bauer, Xiao-guang Zhen, Cheng Xie and Jian Yang
Nature 419, 947–952
(31 October 2002); doi:10.1038/nature01118
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brief communication
A novel Epac-specific cAMP analogue demonstrates independent regulation of Rap1 and ERK
Jorrit M. Enserink, Anne E. Christensen, Johan de Rooij, Miranda van Triest, Frank Schwede, Hans Gottfried Genieser, Stein O. Dřskeland, Jonathan L. Blank and Johannes L. Bos
Nature Cell Biology 4, 901–906
(November 2002); doi:10.1038/ncb874
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news and views
Wnt signalling sees spots
Michael Povelones and Roel Nusse
Nature Cell Biology 4, E249
(November 2002); doi:10.1038/ncb1102-e249
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review article
The cellular and molecular basis of store-operated calcium entry
Kartik Venkatachalam, Damian B. van Rossum, Randen L. Patterson, Hong-Tao Ma and Donald L. Gill
Nature Cell Biology 4, E263
(November 2002); doi:10.1038/ncb1102-e263
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article
CTLA-4-Ig regulates tryptophan catabolism in vivo
Ursula Grohmann, Ciriana Orabona, Francesca Fallarino, Carmine Vacca, Filippo Calcinaro, Alberto Falorni, Paola Candeloro, Maria L. Belladonna, Roberta Bianchi, Maria C. Fioretti and Paolo Puccetti
Nature Immunology 3, 1097–1101
(November 2002); doi:10.1038/ni846
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news and views
When ligand becomes receptor—tolerance via B7 signaling on DCs
Erik B. Finger and Jeffrey A. Bluestone
Nature Immunology 3, 1056–1057
(November 2002); doi:10.1038/ni1102-1056
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review article
Lymphocide: cytokines and the control of lymphoid homeostasis
Annette R. Khaled and Scott K. Durum
Nature Reviews Immunology 2, 817–830
(November 2002); doi:10.1038/nri931
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article
Functional PPAR-g receptor is a novel therapeutic target for ACTH-secreting pituitary adenomas
Anthony P. Heaney, Manory Fernando, William H. Yong and Shlomo Melmed
Nature Medicine 8, 1281–1287
(November 2002); doi:10.1038/nm784
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letter
A critical role for the protein tyrosine phosphatase receptor type Z in functional recovery from demyelinating lesions
Sheila Harroch, Glaucia C. Furtado, Wolfgang Brueck, Jack Rosenbluth, Juan Lafaille, Moses Chao, Joseph D. Buxbaum and Joseph Schlessinger
Nature Genetics 32, 411–414
(November 2002); doi:10.1038/ng1004
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brief communication
EphB receptors regulate dendritic spine development via intersectin, Cdc42 and N-WASP
Fumitoshi Irie and Yu Yamaguchi
Nature Neuroscience 5, 1117–1118
(November 2002); doi:10.1038/nn964
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news and views
How ephrins sculpt dendritic spines
Nature Neuroscience 5, 1113
(November 2002); doi:10.1038/nn1102-1113
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review article
Retinoid signalling in the development of the central nervous system
Malcolm Maden
Nature Reviews Neuroscience 3, 843–853
(November 2002); doi:10.1038/nrn963
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news and views
Spotlight on receptor/transducer interaction
John Spudich
Nature Structural Biology 9, 797–799
(November 2002); doi:10.1038/nsb1102-797
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original paper
Cdk9, a member of the cdc2-like family of kinases, binds to gp130, the receptor of the IL-6 family of cytokines
Giulia De Falco, Luca Maria Neri, Maria De Falco, Cristiana Bellan, Zailin Yu, Antonio De Luca, Lorenzo Leoncini and Antonio Giordano
Oncogene 21, 7464–7470
(24 October 2002); doi:10.1038/sj.onc.1205967
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original paper
The proapoptotic BH3-only protein BAD transduces cell death signals independently of its interaction with Bcl-2
M Adachi and K Imai
Cell death and differentiation 9, 1240–1247
(November 2002); doi:10.1038/sj.cdd.4401097
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