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January 2003
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The Research Library categorizes, and provides access to, all recent signaling-related research published in the Nature Publishing Group journals. The selection is deliberately broad to facilitate access to all research impacting on the signaling community. Both primary research and review articles are included, as are 'News and Views' articles.
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article
DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation
Christopher J. Bakkenist and Michael B. Kastan
Nature 421, 499–506
(30 January 2003); doi:10.1038/nature01368
| Summary | Full Text (HTML / PDF) |
news and views
DNA repair: Damage alert
Jiri Bartek and Jiri Lukas
Nature 421, 486–488
(30 January 2003); doi:10.1038/421486a
| Full Text (HTML / PDF) |
letters to nature
Fidelity in planar cell polarity signalling
Dali Ma, Chung-hui Yang, Helen McNeill, Michael A. Simon and Jeffrey D. Axelrod
Nature 421, 543–547
(30 January 2003); doi:10.1038/nature01366
| First Paragraph | Full Text (HTML / PDF) |
letters to nature
Crystal structure of the human angiotensin-converting enzyme-lisinopril complex
Ramanathan Natesh, Sylva L. U. Schwager, Edward D. Sturrock and K. Ravi Acharya
Nature 421, 551–554
(30 January 2003); doi:10.1038/nature01370
| First Paragraph | Full Text (HTML / PDF) |
letter
Yeast epsin-related proteins required for Golgi-endosome traffic define a γ-adaptin ear-binding motif
Mara C. Duncan, Giancarlo Costaguta and Gregory S. Payne
Nature Cell Biology 5, 77–81
(January 2003); doi:10.1038/ncb901
| First Paragraph | Full Text (HTML/PDF) |
letter
Vimentin is secreted by activated macrophages
Nirit Mor-Vaknin, Antonello Punturieri, Kajal Sitwala and David M. Markovitz
Nature Cell Biology 5, 59–63
(January 2003); doi:10.1038/ncb898
| First Paragraph | Full Text (HTML/PDF) |
article
Lethal T cell immunodeficiency induced by chronic costimulation via CD27-CD70 interactions
Kiki Tesselaar, Ramon Arens, Gijs M.W. van Schijndel, Paul A. Baars, Martin A. van der Valk, Jannie Borst, Marinus H.J. van Oers and René A.W. van Lier
Nature Immunology 4, 49–54
(January 2003); doi:10.1038/ni869
| Abstract | Full Text (HTML/PDF) |
article
TCRs with high affinity for foreign pMHC show self-reactivity
Phillip D. Holler, Lukasz K. Chlewicki and David M. Kranz
Nature Immunology 4, 55–62
(January 2003); doi:10.1038/ni863
| Abstract | Full Text (HTML/PDF) |
article
Memory and flexibility of cytokine gene expression as separable properties of human TH1 and TH2 lymphocytes
Mara Messi, Isabella Giacchetto, Kinya Nagata, Antonio Lanzavecchia, Gioacchino Natoli and Federica Sallusto
Nature Immunology 4, 78–86
(January 2003); doi:10.1038/ni872
| Abstract | Full Text (HTML/PDF) |
review article
Alternative activation of macrophages
Siamon Gordon
Nature Reviews Immunology 3, 23–35
(January 2003); doi:10.1038/nri978
| Summary | Full Text (HTML / PDF) |
article
Circulating activated platelets exacerbate atherosclerosis in mice deficient in apolipoprotein E
Yuqing Huo, Andreas Schober, S. Bradley Forlow, David F. Smith, Matthew Craig Hyman, Steffen Jung, Dan R. Littman, Christian Weber and Klaus Ley
Nature Medicine 9, 61–67
(January 2003); doi:10.1038/nm810
| Abstract | Full Text (HTML/PDF) |
news and views
Unmet expectations: The brain minds
William A. Carlezon Jr. and Roy A. Wise
Nature Medicine 9, 15–16
(January 2003); doi:10.1038/nm0103-15
| Full Text (HTML/PDF) |
review article
Targeting tumours with genetically enhanced T lymphocytes
Michel Sadelain, Isabelle Rivière and Renier Brentjens
Nature Reviews Cancer 3, 35–45
(January 2003); doi:10.1038/nrc971
| Summary | Full Text (HTML / PDF) |
article
A Robertsonian translocation suppresses a somatic recombination pathway to loss of heterozygosity
Kevin M. Haigis and William F. Dove
Nature Genetics 33, 33–39
(January 2003); doi:10.1038/ng1055
| Abstract | Full Text (HTML/PDF) |
news and views
Somatic recombination redux
Jay A. Tischfield and Changshun Shao
Nature Genetics 33, 5–6
(January 2003); doi:10.1038/ng0103-5
| Full Text (HTML/PDF) |
article
Neuron-to-astrocyte signaling is central to the dynamic control of brain microcirculation
Micaela Zonta, María Cecilia Angulo, Sara Gobbo, Bernhard Rosengarten, Konstantin-A. Hossmann, Tullio Pozzan and Giorgio Carmignoto
Nature Neuroscience 6, 43–50
(January 2003); doi:10.1038/nn980
| Abstract | Full Text (HTML/PDF) |
news and views
An astrocyte bridge from synapse to blood flow
Rheinallt Parri and Vincenzo Crunelli
Nature Neuroscience 6, 5–6
(January 2003); doi:10.1038/nn0103-5
| Full Text (HTML/PDF) |
article
Evolutionarily conserved networks of residues mediate allosteric communication in proteins
Gürol M. Süel, Steve W. Lockless, Mark A. Wall and Rama Ranganathan
Nature Structural Biology 10, 59–69
(January 2003); doi:10.1038/nsb881
| Abstract | Full Text (HTML/PDF) |
review article
Scientific and therapeutic advances in antiplatelet therapy
Deepak L. Bhatt and Eric J. Topol
Nature Reviews Drug Discovery 2, 15–28
(January 2003); doi:10.1038/nrd985
| Summary | Full Text (HTML / PDF) |
original paper
H-Ras-specific activation of NF-κB protects NIH 3T3 cells against stimulus-dependent apoptosis
Olga Millán, Alicia Ballester, Antonio Castrillo, José Luis de la Oliva, Paqui G Través, José María Rojas and Lisardo Boscá
Oncogene 22, 477–483
(30 January 2003); doi:10.1038/sj.onc.1206179
| Abstract |
letters to nature
A role for Drosophila LKB1 in anterior-posterior axis formation and epithelial polarity
Sophie G. Martin and Daniel St Johnston
Nature 421, 379–384
(23 January 2003); doi:10.1038/nature01296
| First Paragraph | Full Text (HTML / PDF) |
letters to nature
Nicotinic acetylcholine receptor α7 subunit is an essential regulator of inflammation
Hong Wang, Man Yu, Mahendar Ochani, Carol Ann Amella, Mahira Tanovic, Seenu Susarla, Jian Hua Li, Haichao Wang, Huan Yang, Luis Ulloa, Yousef Al-Abed, Christopher J. Czura and Kevin J. Tracey
Nature 421, 384–388
(23 January 2003); doi:10.1038/nature01339
| First Paragraph | Full Text (HTML / PDF) |
news and views
Inflammation: A nervous connection
Claude Libert
Nature 421, 328–329
(23 January 2003); doi:10.1038/421328a
| Full Text (HTML / PDF) |
letters to nature
Activation of human CD4+ cells with CD3 and CD46 induces a T-regulatory cell 1 phenotype
Claudia Kemper, Andrew C. Chan, Jonathan M. Green, Kelly A. Brett, Kenneth M. Murphy and John P. Atkinson
Nature 421, 388–392
(23 January 2003); doi:10.1038/nature01315
| First Paragraph | Full Text (HTML / PDF) |
news and views
Neurobiology: Fear thou not
Yadin Dudai
Nature 421, 325–327
(23 January 2003); doi:10.1038/421325a
| Full Text (HTML / PDF) |
letter
Regulation of microtubule stability by the von Hippel-Lindau tumour suppressor protein pVHL
Alexander Hergovich, Joanna Lisztwan, Robert Barry, Pia Ballschmieter and Wilhelm Krek
Nature Cell Biology 5, 64–70
(January 2003); doi:10.1038/ncb899
| First Paragraph | Full Text (HTML/PDF) |
news and views
New insights into an enigmatic tumour suppressor
Peter J. Ratcliffe
Nature Cell Biology 5, 7–8
(January 2003); doi:10.1038/ncb0103-7
| Full Text (HTML/PDF) |
review article
Entry of viruses through the epithelial barrier: Pathogenic trickery
Morgane Bomsel and Annette Alfsen
Nature Reviews Molecular Cell Biology 4, 57–68
(January 2003); doi:10.1038/nrm1005
| Summary | Full Text (HTML / PDF) |
article
Essential role of Id2 in negative regulation of IgE class switching
Manabu Sugai, Hiroyuki Gonda, Takashi Kusunoki, Tomoya Katakai, Yoshifumi Yokota and Akira Shimizu
Nature Immunology 4, 25–30
(January 2003); doi:10.1038/ni874
| Abstract | Full Text (HTML/PDF) |
news and views
Yin outwits Yang at the IgE locus
Nancy Maizels
Nature Immunology 4, 7–8
(January 2003); doi:10.1038/ni0103-7
| Full Text (HTML/PDF) |
news and views
Regulatory T cells: mediating compromises between host and parasite
Shimon Sakaguchi
Nature Immunology 4, 10–11
(January 2003); doi:10.1038/ni0103-10
| Full Text (HTML/PDF) |
review article
The dual-function CD150 receptor subfamily: the viral attraction
Svetlana P. Sidorenko and Edward A. Clark
Nature Immunology 4, 19–24
(January 2003); doi:10.1038/ni0103-19
| Abstract | Full Text (HTML/PDF) |
article
Interleukin-4 therapy of psoriasis induces Th2 responses and improves human autoimmune disease
Kamran Ghoreschi, Peter Thomas, Susanne Breit, Martin Dugas, Reinhard Mailhammer, Willem van Eden, Ruurd van der Zee, Tilo Biedermann, Jörg Prinz, Matthias Mack, Ulrich Mrowietz, Enno Christophers, Detlef Schlöndorff, Gerd Plewig, Christian A. Sander and Martin Röcken
Nature Medicine 9, 40–46
(January 2003); doi:10.1038/nm804
| Abstract | Full Text (HTML/PDF) |
news and views
The nucleolus: at the stem of immortality
Rosa Bernardi and Pier Paolo Pandolfi
Nature Medicine 9, 24–25
(January 2003); doi:10.1038/nm0103-24
| Full Text (HTML/PDF) |
news and views
Predicting the future of breast cancer
Åke Borg, Mårten Fernö and Carsten Peterson
Nature Medicine 9, 16–18
(January 2003); doi:10.1038/nm0103-16
| Full Text (HTML/PDF) |
review article
Validating survivin as a cancer therapeutic target
Dario C. Altieri
Nature Reviews Cancer 3, 46–54
(January 2003); doi:10.1038/nrc968
| Summary | Full Text (HTML / PDF) |
letter
The mismatch repair system is required for S-phase checkpoint activation
Kevin D. Brown, Abhilasha Rathi, Ravindra Kamath, Dillon I. Beardsley, Qimin Zhan, Jennifer L. Mannino and R Baskaran
Nature Genetics 33, 80–84
(January 2003); doi:10.1038/ng1052
| First Paragraph | Full Text (HTML/PDF) |
article
Sonic hedgehog regulates adult neural progenitor proliferation in vitro and in vivo
Karen Lai, Brian K. Kaspar, Fred H. Gage and David V. Schaffer
Nature Neuroscience 6, 21–27
(January 2003); doi:10.1038/nn983
| Abstract | Full Text (HTML/PDF) |
review article
Plasma membrane monoamine transporters: structure, regulation and function
Gonzalo E. Torres, Raul R. Gainetdinov and Marc G. Caron
Nature Reviews Neuroscience 4, 13–25
(January 2003); doi:10.1038/nrn1008
| Summary | Full Text (HTML / PDF) |
article
Automated design of specificity in molecular recognition
James J. Havranek and Pehr B. Harbury
Nature Structural Biology 10, 45–52
(January 2003); doi:10.1038/nsb877
| Abstract | Full Text (HTML/PDF) |
original paper
Stat3 activation regulates the expression of vascular endothelial growth factor and human pancreatic cancer angiogenesis and metastasis
Daoyan Wei, Xiangdong Le, Leizhen Zheng, Liwei Wang, Jennifer A Frey, Allen C Gao, Zhihai Peng, Suyun Huang, Henry Q Xiong, James L Abbruzzese and Keping Xie
Oncogene 22, 319–329
(23 January 2003); doi:10.1038/sj.onc.1206122
| Abstract |
letters to nature
Genome-wide RNAi analysis of Caenorhabditis elegans fat regulatory genes
Kaveh Ashrafi, Francesca Y. Chang, Jennifer L. Watts, Andrew G. Fraser, Ravi S. Kamath, Julie Ahringer and Gary Ruvkun
Nature 421, 268–272
(16 January 2003); doi:10.1038/nature01279
| First Paragraph | Full Text (HTML / PDF) |
news and views
Functional genomics: RNA sets the standard
Thomas Tuschl
Nature 421, 220–221
(16 January 2003); doi:10.1038/421220a
| Full Text (HTML / PDF) |
letters to nature
Coupling of agonist binding to channel gating in the GABAA receptor
Thomas L. Kash, Andrew Jenkins, Jill C. Kelley, James R. Trudell and Neil L. Harrison
Nature 421, 272–275
(16 January 2003); doi:10.1038/nature01280
| First Paragraph | Full Text (HTML / PDF) |
letters to nature
Periodic Notch inhibition by Lunatic Fringe underlies the chick segmentation clock
J. K. Dale, M. Maroto, M.-L. Dequeant, P. Malapert, M. McGrew and O. Pourquie
Nature 421, 275–278
(16 January 2003); doi:10.1038/nature01244
| First Paragraph | Full Text (HTML / PDF) |
letters to nature
A zebrafish homologue of the chemokine receptor Cxcr4 is a germ-cell guidance receptor
Holger Knaut, Christian Werz, Robert Geisler, The Tübingen 2000 Screen Consortium and Christiane Nüsslein-Volhard
Nature 421, 279–282
(16 January 2003); doi:10.1038/nature01338
| First Paragraph | Full Text (HTML / PDF) |
news and views
Developmental biology: Germ-cell attraction
Prabhat S. Kunwar and Ruth Lehmann
Nature 421, 226–227
(16 January 2003); doi:10.1038/421226a
| Full Text (HTML / PDF) |
letters to nature
SAP is required for generating long-term humoral immunity
Shane Crotty, Ellen N. Kersh, Jennifer Cannons, Pamela L. Schwartzberg and Rafi Ahmed
Nature 421, 282–287
(16 January 2003); doi:10.1038/nature01318
| First Paragraph | Full Text (HTML / PDF) |
letters to nature
Direct activation of RNA polymerase III transcription by c-Myc
Natividad Gomez-Roman, Carla Grandori, Robert N. Eisenman and Robert J. White
Nature 421, 290–294
(16 January 2003); doi:10.1038/nature01327
| First Paragraph | Full Text (HTML / PDF) |
news and views
Immunology: Mobilizing the army
Steven D. Shapiro
Nature 421, 223–224
(16 January 2003); doi:10.1038/421223a
| Full Text (HTML / PDF) |
article
Unconventional tethering of Ulp1 to the transport channel of the nuclear pore complex by karyopherins
Vikram Govind Panse, Bernhard Küster, Thomas Gerstberger and Ed Hurt
Nature Cell Biology 5, 21–27
(January 2003); doi:10.1038/ncb893
| Abstract | Full Text (HTML/PDF) |
letter
Integrated activity of PDZ protein complexes regulates epithelial polarity
David Bilder, Markus Schober and Norbert Perrimon
Nature Cell Biology 5, 53–58
(January 2003); doi:10.1038/ncb897
| First Paragraph | Full Text (HTML/PDF) |
review article
CD44: From adhesion molecules to signalling regulators
Helmut Ponta, Larry Sherman and Peter A. Herrlich
Nature Reviews Molecular Cell Biology 4, 33–45
(January 2003); doi:10.1038/nrm1004
| Summary | Full Text (HTML / PDF) |
article
IL-28, IL-29 and their class II cytokine receptor IL-28R
Paul Sheppard, Wayne Kindsvogel, Wenfeng Xu, Katherine Henderson, Stacy Schlutsmeyer, Theodore E. Whitmore, Rolf Kuestner, Ursula Garrigues, Carl Birks, Jenny Roraback, Craig Ostrander, Dennis Dong, Jinu Shin, Scott Presnell, Brian Fox, Betty Haldeman, Emily Cooper, David Taft, Teresa Gilbert, Francis J. Grant, Monica Tackett, William Krivan, Gary McKnight, Chris Clegg, Don Foster and Kevin M. Klucher
Nature Immunology 4, 63–68
(January 2003); doi:10.1038/ni873
| Abstract | Full Text (HTML/PDF) |
article
IFN-λs mediate antiviral protection through a distinct class II cytokine receptor complex
Sergei V. Kotenko, Grant Gallagher, Vitaliy V. Baurin, Anita Lewis-Antes, Meiling Shen, Nital K. Shah, Jerome A. Langer, Faruk Sheikh, Harold Dickensheets and Raymond P. Donnelly
Nature Immunology 4, 69–77
(January 2003); doi:10.1038/ni875
| Abstract | Full Text (HTML/PDF) |
news and views
Novel interferons
Jan Vilcek
Nature Immunology 4, 8–9
(January 2003); doi:10.1038/ni0103-8
| Full Text (HTML/PDF) |
review article
Intracellular pathways of CD1 antigen presentation
D. Branch Moody and Steven A. Porcelli
Nature Reviews Immunology 3, 11–22
(January 2003); doi:10.1038/nri979
| Summary | Full Text (HTML / PDF) |
article
In vivo imaging of transcriptionally active estrogen receptors
Paolo Ciana, Michele Raviscioni, Paola Mussi, Elisabetta Vegeto, Ivo Que, Malcolm G. Parker, Clemens Lowik and Adriana Maggi
Nature Medicine 9, 82–86
(January 2003); doi:10.1038/nm809
| Abstract | Full Text (HTML/PDF) |
news and views
In vivo imaging reveals estrogen receptor's hidden personality
Geoffrey L. Greene
Nature Medicine 9, 22–23
(January 2003); doi:10.1038/nm0103-22
| Full Text (HTML/PDF) |
news and views
Myelin management
Charlotte Schubert
Nature Medicine 9, 18
(January 2003); doi:10.1038/nm0103-18
| Full Text (HTML/PDF) |
review article
Targeting RAS signalling pathways in cancer therapy
Julian Downward
Nature Reviews Cancer 3, 11–22
(January 2003); doi:10.1038/nrc969
| Summary | Full Text (HTML / PDF) |
brief communication
High frequency of BRAF mutations in nevi
Pamela M. Pollock, Ursula L. Harper, Katherine S. Hansen, Laura M. Yudt, Mitchell Stark, Christiane M. Robbins, Tracy Y. Moses, Galen Hostetter, Urs Wagner, John Kakareka, Ghadi Salem, Tom Pohida, Peter Heenan, Paul Duray, Olli Kallioniemi, Nicholas K. Hayward, Jeffrey M. Trent and Paul S. Meltzer
Nature Genetics 33, 19–20
(January 2003); doi:10.1038/ng1054
| First Paragraph | Full Text (HTML/PDF) |
article
Zinc finger protein too few controls the development of monoaminergic neurons
Gil Levkowitz, Jörg Zeller, Howard I. Sirotkin, Dorothy French, Sarah Schilbach, Hisashi Hashimoto, Masahiko Hibi, William S. Talbot and Arnon Rosenthal
Nature Neuroscience 6, 28–33
(January 2003); doi:10.1038/nn979
| Abstract | Full Text (HTML/PDF) |
article
Angiopoietins have distinct modular domains essential for receptor binding, dimerization and superclustering
Samuel Davis, Nick Papadopoulos, Thomas H. Aldrich, Peter C. Maisonpierre, Tammy Huang, Lubomir Kovac, April Xu, Raymond Leidich, Elzbieta Radziejewska, Ashique Rafique, Judah Goldberg, Vivek Jain, Kevin Bailey, Margaret Karow, Jim Fandl, Steven J. Samuelsson, Ella Ioffe, John S. Rudge, Thomas J. Daly, Czeslaw Radziejewski and George D. Yancopoulos
Nature Structural Biology 10, 38–44
(January 2003); doi:10.1038/nsb880
| Abstract | Full Text (HTML/PDF) |
letters to nature
IGF-1 receptor regulates lifespan and resistance to oxidative stress in mice
Martin Holzenberger, Joëlle Dupont, Bertrand Ducos, Patricia Leneuve, Alain Géloën, Patrick C. Even, Pascale Cervera and Yves Le Bouc
Nature 421, 182–187
(09 January 2003); doi:10.1038/nature01298
| First Paragraph | Full Text (HTML / PDF) |
news and views
Physiology: Cost-free longevity in mice?
Gordon J. Lithgow and Matthew S. Gill
Nature 421, 125–126
(09 January 2003); doi:10.1038/421125a
| Full Text (HTML / PDF) |
letters to nature
Srb10/Cdk8 regulates yeast filamentous growth by phosphorylating the transcription factor Ste12
Chris Nelson, Susan Goto, Karen Lund, Wesley Hung and Ivan Sadowski
Nature 421, 187–190
(09 January 2003); doi:10.1038/nature01243
| First Paragraph | Full Text (HTML / PDF) |
article
Inherent calcineurin inhibitor FKBP38 targets Bcl-2 to mitochondria and inhibits apoptosis
Michiko Shirane and Keiichi I. Nakayama
Nature Cell Biology 5, 28–37
(January 2003); doi:10.1038/ncb894
| Abstract | Full Text (HTML/PDF) |
news and views
Defying death: showing Bcl-2 the way home
Colin Adrain, Emma M. Creagh and Seamus J. Martin
Nature Cell Biology 5, 9–11
(January 2003); doi:10.1038/ncb0103-9a
| Full Text (HTML/PDF) |
review article
Nongenomic actions of steroid hormones
Ralf Lösel and Martin Wehling
Nature Reviews Molecular Cell Biology 4, 46–55
(January 2003); doi:10.1038/nrm1009
| Summary | Full Text (HTML / PDF) |
article
Tyrosine phosphorylation of VHR phosphatase by ZAP-70
Andres Alonso, Souad Rahmouni, Scott Williams, Marianne van Stipdonk, Lukasz Jaroszewski, Adam Godzik, Robert T. Abraham, Stephen P. Schoenberger and Tomas Mustelin
Nature Immunology 4, 44–48
(January 2003); doi:10.1038/ni856
| Abstract | Full Text (HTML/PDF) |
news and views
ZAP-ping T-cell activation
Sarah Greaves
Nature Cell Biology 5, 13
(January 2003); doi:10.1038/ncb0103-13
| Full Text (HTML/PDF) |
article
Serum-derived protein S binds to phosphatidylserine and stimulates the phagocytosis of apoptotic cells
Howard A. Anderson, Caroline A. Maylock, Joy A. Williams, Cloud P. Paweletz, Hongjun Shu and Emily Shacter
Nature Immunology 4, 87–91
(January 2003); doi:10.1038/ni871
| Abstract | Full Text (HTML/PDF) |
review article
Hepatic T cells and liver tolerance
Ian Nicholas Crispe
Nature Reviews Immunology 3, 51–62
(January 2003); doi:10.1038/nri981
| Summary | Full Text (HTML / PDF) |
article
Melusin, a muscle-specific integrin β1-interacting protein, is required to prevent cardiac failure in response to chronic pressure overload
Mara Brancaccio, Luigi Fratta, Antonella Notte, Emilio Hirsch, Roberta Poulet, Simona Guazzone, Marika De Acetis, Carmine Vecchione, Gennaro Marino, Fiorella Altruda, Lorenzo Silengo, Guido Tarone and Giuseppe Lembo
Nature Medicine 9, 68–75
(January 2003); doi:10.1038/nm805
| Abstract | Full Text (HTML/PDF) |
news and views
Sensing heart stress
Liza Barki-Harrington and Howard A. Rockman
Nature Medicine 9, 19–20
(January 2003); doi:10.1038/nm0103-19
| Full Text (HTML/PDF) |
review article
The Fanconi anaemia/BRCA pathway
Alan D. D'Andrea and Markus Grompe
Nature Reviews Cancer 3, 23–34
(January 2003); doi:10.1038/nrc970
| Summary | Full Text (HTML / PDF) |
article
A systematic RNAi screen identifies a critical role for mitochondria in C. elegans longevity
Siu Sylvia Lee, Raymond Y.N. Lee, Andrew G. Fraser, Ravi S. Kamath, Julie Ahringer and Gary Ruvkun
Nature Genetics 33, 40–48
(January 2003); doi:10.1038/ng1056
| Abstract | Full Text (HTML/PDF) |
article
NMDA-mediated activation of the tyrosine phosphatase STEP regulates the duration of ERK signaling
Surojit Paul, Angus C. Nairn, Ping Wang and Paul J. Lombroso
Nature Neuroscience 6, 34–42
(January 2003); doi:10.1038/nn989
| Abstract | Full Text (HTML/PDF) |
article
Selective cognitive dysfunction in acetylcholine M1 muscarinic receptor mutant mice
Stephan G. Anagnostaras, Geoffrey G. Murphy, Susan E. Hamilton, Scott L. Mitchell, Nancy P. Rahnama, Neil M. Nathanson and Alcino J. Silva
Nature Neuroscience 6, 51–58
(January 2003); doi:10.1038/nn992
| Abstract | Full Text (HTML/PDF) |
article
Crystal structure of human dipeptidyl peptidase IV/CD26 in complex with a substrate analog
Hanne B. Rasmussen, Sven Branner, Finn C. Wiberg and Nicolai Wagtmann
Nature Structural Biology 10, 19–25
(January 2003); doi:10.1038/nsb882
| Abstract | Full Text (HTML/PDF) |
news and views
First bite
Mark D. Gorrell
Nature Structural Biology 10, 3–5
(January 2003); doi:10.1038/nsb0103-3
| Full Text (HTML/PDF) |
letters to nature
Role of duplicate genes in genetic robustness against null mutations
Zhenglong Gu, Lars M. Steinmetz, Xun Gu, Curt Scharfe, Ronald W. Davis and Wen-Hsiung Li
Nature 421, 63–66
(02 January 2003); doi:10.1038/nature01198
| First Paragraph | Full Text (HTML / PDF) |
news and views
Molecular evolution: Duplication, duplication
Axel Meyer
Nature 421, 31–32
(02 January 2003); doi:10.1038/421031a
| Full Text (HTML / PDF) |
letters to nature
Extinction-induced upregulation in AMPA receptors reduces cocaine-seeking behaviour
Michael A. Sutton, Eric F. Schmidt, Kwang-Ho Choi, Christina A. Schad, Kim Whisler, Diana Simmons, David A. Karanian, Lisa M. Monteggia, Rachael L. Neve and David W. Self
Nature 421, 70–75
(02 January 2003); doi:10.1038/nature01249
| First Paragraph | Full Text (HTML / PDF) |
letters to nature
Ectopic β-chain of ATP synthase is an apolipoprotein A-I receptor in hepatic HDL endocytosis
Laurent O. Martinez, Sébastien Jacquet, Jean-Pierre Esteve, Corinne Rolland, Elena Cabezón, Eric Champagne, Thierry Pineau, Valérie Georgeaud, John E. Walker, François Tercé, Xavier Collet, Bertrand Perret and Ronald Barbaras
Nature 421, 75–79
(02 January 2003); doi:10.1038/nature01250
| First Paragraph | Full Text (HTML / PDF) |
letters to nature
Chloroplast to nucleus communication triggered by accumulation of Mg-protoporphyrinIX
Åsa Strand, Tadao Asami, Jose Alonso, Joseph R. Ecker and Joanne Chory
Nature 421, 79–83
(02 January 2003); doi:10.1038/nature01204
| First Paragraph | Full Text (HTML / PDF) |
letters to nature
Moesin functions antagonistically to the Rho pathway to maintain epithelial integrity
Olga Speck, Sarah C. Hughes, Nicole K. Noren, Rima M. Kulikauskas and Richard G. Fehon
Nature 421, 83–87
(02 January 2003); doi:10.1038/nature01295
| First Paragraph | Full Text (HTML / PDF) |
article
Signalling and crosstalk of Rho GTPases in mediating axon guidance
Xiao-bing Yuan, Ming Jin, Xiaohua Xu, Yuan-quan Song, Chien-ping Wu, Mu-ming Poo and Shumin Duan
Nature Cell Biology 5, 38–45
(January 2003); doi:10.1038/ncb895
| Abstract | Full Text (HTML/PDF) |
letter
Interactions between the crumbs, lethal giant larvae and bazooka pathways in epithelial polarization
Guy Tanentzapf and Ulrich Tepass
Nature Cell Biology 5, 46–52
(January 2003); doi:10.1038/ncb896
| First Paragraph | Full Text (HTML/PDF) |
news and views
A genetic hierarchy controlling cell polarity
Kevin Johnson and Andreas Wodarz
Nature Cell Biology 5, 12–14
(January 2003); doi:10.1038/ncb0103-12
| Full Text (HTML/PDF) |
review article
Border-cell migration: The race is on
Denise J. Montell
Nature Reviews Molecular Cell Biology 4, 13–24
(January 2003); doi:10.1038/nrm1006
| Summary | Full Text (HTML / PDF) |
article
A small molecule Abl kinase inhibitor induces differentiation of Abelson virus-transformed pre-B cell lines
Stefan A. Muljo and Mark S. Schlissel
Nature Immunology 4, 31–37
(January 2003); doi:10.1038/ni870
| Abstract | Full Text (HTML/PDF) |
article
The adaptor protein SLP-65 acts as a tumor suppressor that limits pre-B cell expansion
Alexandra Flemming, Tilman Brummer, Michael Reth and Hassan Jumaa
Nature Immunology 4, 38–43
(January 2003); doi:10.1038/ni862
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news and views
Checks and balances on developing B cells
Tomohiro Kurosaki
Nature Immunology 4, 13–15
(January 2003); doi:10.1038/ni0103-13
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review article
Viral mimicry of cytokines, chemokines and their receptors
Antonio Alcami
Nature Reviews Immunology 3, 36–50
(January 2003); doi:10.1038/nri980
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article
Cytokine traps: multi-component, high-affinity blockers of cytokine action
Aris N. Economides, Laura Rocco Carpenter, John S. Rudge, Vivien Wong, Ellen M. Koehler-Stec, Christopher Hartnett, Erica A. Pyles, Xiaobing Xu, Thomas J. Daly, Michael R. Young, James P. Fandl, Frank Lee, Scott Carver, Jennifer McNay, Kevin Bailey, Swayampakula Ramakanth, Renta Hutabarat, Tammy T. Huang, Czeslaw Radziejewski, George D. Yancopoulos and Neil Stahl
Nature Medicine 9, 47–52
(January 2003); doi:10.1038/nm811
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Setting the cytokine trap for autoimmunity
Charles A. Dinarello
Nature Medicine 9, 20–22
(January 2003); doi:10.1038/nm0103-20
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review article
Metastasis suppressors alter the signal transduction of cancer cells
Patricia S. Steeg
Nature Reviews Cancer 3, 55–63
(January 2003); doi:10.1038/nrc967
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letter
Nf1 has an essential role in endothelial cells
Aaron D. Gitler, Yuan Zhu, Fraz A. Ismat, Min Min Lu, Yasutaka Yamauchi, Luis F. Parada and Jonathan A. Epstein
Nature Genetics 33, 75–79
(January 2003); doi:10.1038/ng1059
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news and views
Cre-constructing the heart
Pilar Ruiz-Lozano and Kenneth R. Chien
Nature Genetics 33, 8–9
(January 2003); doi:10.1038/ng0103-8
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brief communication
A developmental switch in the signaling cascades for LTP induction
Hiroki Yasuda, Alison L. Barth, David Stellwagen and Robert C. Malenka
Nature Neuroscience 6, 15–16
(January 2003); doi:10.1038/nn985
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article
Structure and regulation of the cAMP-binding domains of Epac2
Holger Rehmann, Balaji Prakash, Eva Wolf, Alma Rueppel, Johan de Rooij, Johannes L. Bos and Alfred Wittinghofer
Nature Structural Biology 10, 26–32
(January 2003); doi:10.1038/nsb878
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