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February 2003
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The Research Library categorizes, and provides access to, all recent signaling-related research published in the Nature Publishing Group journals. The selection is deliberately broad to facilitate access to all research impacting on the signaling community. Both primary research and review articles are included, as are 'News and Views' articles.
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letters to nature
Extra-embryonic function of Rb is essential for embryonic development and viability
Lizhao Wu, Alain de Bruin, Harold I. Saavedra, Maja Starovic, Anthony Trimboli, Ying Yang, Jana Opavska, Pamela Wilson, John C. Thompson, Michael C. Ostrowski, Thomas J. Rosol, Laura A. Woollett, Michael Weinstein, James C. Cross, Michael L. Robinson and Gustavo Leone
Nature 421, 942–947
(27 February 2003); doi:10.1038/nature01417
| First Paragraph | Full Text (HTML / PDF) |
news and views
Developmental biology: A twist in a mouse tale
Nick Dyson
Nature 421, 903–904
(27 February 2003); doi:10.1038/421903a
| Full Text (HTML / PDF) |
letters to nature
MDC1 is required for the intra-S-phase DNA damage checkpoint
Michal Goldberg, Manuel Stucki, Jacob Falck, Damien D'Amours, Dinah Rahman, Darryl Pappin, Jiri Bartek and Stephen P. Jackson
Nature 421, 952–956
(27 February 2003); doi:10.1038/nature01445
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letters to nature
MDC1 is coupled to activated CHK2 in mammalian DNA damage response pathways
Zhenkun Lou, Katherine Minter-Dykhouse, Xianglin Wu and Junjie Chen
Nature 421, 957–961
(27 February 2003); doi:10.1038/nature01447
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letters to nature
MDC1 is a mediator of the mammalian DNA damage checkpoint
Grant S. Stewart, Bin Wang, Colin R. Bignell, A. Malcolm R. Taylor and Stephen J. Elledge
Nature 421, 961–966
(27 February 2003); doi:10.1038/nature01446
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news and views
Cell polarity: From embryo to axon
Melissa M. Rolls and Chris Q. Doe
Nature 421, 905–906
(27 February 2003); doi:10.1038/421905a
| Full Text (HTML / PDF) |
letter
Active cyclin B1-Cdk1 first appears on centrosomes in prophase
Mark Jackman, Catherine Lindon, Erich A. Nigg and Jonathon Pines
Nature Cell Biology 5, 143–148
(February 2003); doi:10.1038/ncb918
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letter
SAP couples Fyn to SLAM immune receptors
Betty Chan, Arpad Lanyi, Hyun Kyu Song, Jan Griesbach, Maria Simarro-Grande, Florence Poy, Duncan Howie, Janos Sumegi, Cox Terhorst and Michael J. Eck
Nature Cell Biology 5, 155–160
(February 2003); doi:10.1038/ncb920
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letter
Dlg, Scrib and Lgl regulate neuroblast cell size and mitotic spindle asymmetry
Roger Albertson and Chris Q. Doe
Nature Cell Biology 5, 166–170
(February 2003); doi:10.1038/ncb922
| First Paragraph | Full Text (HTML/PDF) |
review article
Temporal and spatial coordination of exocytosis and endocytosis
Eckart D. Gundelfinger, Michael M. Kessels and Britta Qualmann
Nature Reviews Molecular Cell Biology 4, 127–139
(February 2003); doi:10.1038/nrm1016
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article
Cleaving the oxidative repair protein Ape1 enhances cell death mediated by granzyme A
Zusen Fan, Paul J. Beresford, Dong Zhang, Zhan Xu, Carl D. Novina, Akira Yoshida, Yves Pommier and Judy Lieberman
Nature Immunology 4, 145–153
(February 2003); doi:10.1038/ni885
| Abstract | Full Text (HTML/PDF) |
news and views
Granzyme A: the road less traveled
Michael J. Pinkoski and Douglas R. Green
Nature Immunology 4, 106–108
(February 2003); doi:10.1038/ni0203-106
| Full Text (HTML/PDF) |
article
CD45 ectodomain controls interaction with GEMs and Lck activity for optimal TCR signaling
Claudine Irles, Antony Symons, Frédérique Michel, Talitha R. Bakker, P. Anton van der Merwe and Oreste Acuto
Nature Immunology 4, 189–197
(February 2003); doi:10.1038/ni877
| Abstract | Full Text (HTML/PDF) |
review article
CD3-specific antibody-induced active tolerance: from bench to bedside
Lucienne Chatenoud
Nature Reviews Immunology 3, 123–132
(February 2003); doi:10.1038/nri1000
| Summary | Full Text (HTML / PDF) |
perspectives
Timeline: Innate immune sensing and its roots: the story of endotoxin
Bruce Beutler and Ernst Th. Rietschel
Nature Reviews Immunology 3, 169–176
(February 2003); doi:10.1038/nri1004
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article
Autoimmune islet destruction in spontaneous type 1 diabetes is not β-cell exclusive
Shawn Winer, Hubert Tsui, Ambrose Lau, Aihua Song, Xiaomao Li, Roy K. Cheung, Anastazia Sampson, Fatemeh Afifiyan, Alisha Elford, George Jackowski, Dorothy J. Becker, Pere Santamaria, Pamela Ohashi and H -Michael Dosch
Nature Medicine 9, 198–205
(February 2003); doi:10.1038/nm818
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news and views
Murder mysteries in type 1 diabetes
Daniel L. Kaufman
Nature Medicine 9, 161–162
(February 2003); doi:10.1038/nm0203-161
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article
Tolerance is dependent on complement C3 fragment iC3b binding to antigen-presenting cells
Jeong-Hyeon Sohn, Puran S. Bora, Hye-Jung Suk, Hector Molina, Henry J. Kaplan and Nalini S. Bora
Nature Medicine 9, 206–212
(February 2003); doi:10.1038/nm814
| Abstract | Full Text (HTML/PDF) |
news and views
B cell memory: Sapping the T cell
Raymond M. Welsh, Susan E. Stepp and Eva Szomolanyi-Tsuda
Nature Medicine 9, 164–166
(February 2003); doi:10.1038/nm0203-164
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review article
The endothelin axis: emerging role in cancer
Joel Nelson, Anna Bagnato, Bruno Battistini and Perry Nisen
Nature Reviews Cancer 3, 110–116
(February 2003); doi:10.1038/nrc990
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review article
The role of p53 in determining sensitivity to radiotherapy
Andrei V. Gudkov and Elena A. Komarova
Nature Reviews Cancer 3, 117–129
(February 2003); doi:10.1038/nrc992
| Summary | Full Text (HTML / PDF) |
letter
iASPP oncoprotein is a key inhibitor of p53 conserved from worm to human
Daniele Bergamaschi, Yardena Samuels, Nigel J. O'Neil, Giuseppe Trigiante, Tim Crook, Jung-Kuang Hsieh, Daniel J. O'Connor, Shan Zhong, Isabelle Campargue, Matthew L. Tomlinson, Patricia E. Kuwabara and Xin Lu
Nature Genetics 33, 162–167
(February 2003); doi:10.1038/ng1070
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letter
A thermosensory pathway controlling flowering time in Arabidopsis thaliana
Miguel A. Blázquez, Ji Hoon Ahn and Detlef Weigel
Nature Genetics 33, 168–171
(February 2003); doi:10.1038/ng1085
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letter
t(11;19)(q21;p13) translocation in mucoepidermoid carcinoma creates a novel fusion product that disrupts a Notch signaling pathway
Giovanni Tonon, Sanjay Modi, Lizi Wu, Akihito Kubo, Amy B. Coxon, Takefumi Komiya, Kevin O'Neil, Kristen Stover, Adel El-Naggar, James D. Griffin, Ilan R. Kirsch and Frederic J. Kaye
Nature Genetics 33, 208–213
(February 2003); doi:10.1038/ng1083
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article
Activation of the transcription factor NF-κB in Schwann cells is required for peripheral myelin formation
Joshua C. Nickols, William Valentine, Sujata Kanwal and Bruce D. Carter
Nature Neuroscience 6, 161–167
(February 2003); doi:10.1038/nn995
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news and views
Insulating axons via NF-κB
Mark P. Mattson
Nature Neuroscience 6, 105–106
(February 2003); doi:10.1038/nn0203-105
| Full Text (HTML/PDF) |
brief communication
The eye is necessary for a circadian rhythm in the suprachiasmatic nucleus
Han S. Lee, Jennifer L. Nelms, Mary Nguyen, Rae Silver and Michael N. Lehman
Nature Neuroscience 6, 111–112
(February 2003); doi:10.1038/nn1006
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news and views
The master clock becomes a servant
Brian Fiske
Nature Neuroscience 6, 108
(February 2003); doi:10.1038/nn0203-108
| Full Text (HTML/PDF) |
letters to nature
CD4+ T cells are required for secondary expansion and memory in CD8+ T lymphocytes
Edith M. Janssen, Edward E. Lemmens, Tom Wolfe, Urs Christen, Matthias G. von Herrath and Stephen P. Schoenberger
Nature 421, 852–856
(20 February 2003); doi:10.1038/nature01441
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letters to nature
STAT3 signalling is required for leptin regulation of energy balance but not reproduction
Sarah H. Bates, Walter H. Stearns, Trevor A. Dundon, Markus Schubert, Annette W. K. Tso, Yongping Wang, Alexander S. Banks, Hugh J. Lavery, Asma K. Haq, Eleftheria Maratos-Flier, Benjamin G. Neel, Michael W. Schwartz and Martin G. Myers Jr
Nature 421, 856–859
(20 February 2003); doi:10.1038/nature01388
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news and views
Molecular chaperones: Plugging the transport gap
R. John Ellis
Nature 421, 801–802
(20 February 2003); doi:10.1038/421801a
| Full Text (HTML / PDF) |
letter
Direct interaction of two polarity complexes implicated in epithelial tight junction assembly
Toby W. Hurd, Lin Gao, Michael H. Roh, Ian G. Macara and Ben Margolis
Nature Cell Biology 5, 137–142
(February 2003); doi:10.1038/ncb923
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letter
Repeated phosphopeptide motifs in Claspin mediate the regulated binding of Chk1
Akiko Kumagai and William G. Dunphy
Nature Cell Biology 5, 161–165
(February 2003); doi:10.1038/ncb921
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brief communication
Native Myosin-IXb is a plus-, not a minus-end-directed motor
Christopher B. O'Connell and Mark S. Mooseker
Nature Cell Biology 5, 171–172
(February 2003); doi:10.1038/ncb924
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news and views
Mitochondria, AIF and caspases — rivaling for cell death execution
Josef M. Penninger and Guido Kroemer
Nature Cell Biology 5, 97–99
(February 2003); doi:10.1038/ncb0203-97
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article
Thymopoiesis independent of common lymphoid progenitors
David Allman, Arivazhagan Sambandam, Sungjune Kim, Juli P. Miller, Antonio Pagan, David Well, Anita Meraz and Avinash Bhandoola
Nature Immunology 4, 168–174
(February 2003); doi:10.1038/ni878
| Abstract | Full Text (HTML/PDF) |
news and views
To T or not to T: reassessing the common lymphoid progenitor
Encarnacion Montecino-Rodriguez and Kenneth Dorshkind
Nature Immunology 4, 100–101
(February 2003); doi:10.1038/ni0203-100
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article
Functional interactions between dendritic cells and NK cells during viral infection
Daniel M. Andrews, Anthony A. Scalzo, Wayne M. Yokoyama, Mark J. Smyth and Mariapia A. Degli-Esposti
Nature Immunology 4, 175–181
(February 2003); doi:10.1038/ni880
| Abstract | Full Text (HTML/PDF) |
review article
Hide, shield and strike back: how HIV-infected cells avoid immune eradication
B. Matija Peterlin and Didier Trono
Nature Reviews Immunology 3, 97–107
(February 2003); doi:10.1038/nri998
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article
HIV-1 Tat reprograms immature dendritic cells to express chemoattractants for activated T cells and macrophages
Elena Izmailova, Frederic M.N. Bertley, Qian Huang, Norbert Makori, Christopher J. Miller, Richard A. Young and Anna Aldovini
Nature Medicine 9, 191–197
(February 2003); doi:10.1038/nm822
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news and views
Tat's seductive side
Mario Stevenson
Nature Medicine 9, 163–164
(February 2003); doi:10.1038/nm0203-163
| Full Text (HTML/PDF) |
article
Reciprocal regulation of inflammation and lipid metabolism by liver X receptors
Sean B. Joseph, Antonio Castrillo, Bryan A. Laffitte, David J. Mangelsdorf and Peter Tontonoz
Nature Medicine 9, 213–219
(February 2003); doi:10.1038/nm820
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news and views
eLiXiRs for restraining inflammation
Mason W. Freeman and Kathryn J. Moore
Nature Medicine 9, 168–169
(February 2003); doi:10.1038/nm0203-168
| Full Text (HTML/PDF) |
review article
Inhibiting the p53-MDM2 interaction: an important target for cancer therapy
Patrick Chène
Nature Reviews Cancer 3, 102–109
(February 2003); doi:10.1038/nrc991
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article
Actin has a molecular scaffolding, not propulsive, role in presynaptic function
Sethuraman Sankaranarayanan, Pradeep P. Atluri and Timothy A. Ryan
Nature Neuroscience 6, 127–135
(February 2003); doi:10.1038/nn1002
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news and views
Actin in a supporting role
Shelley Halpain
Nature Neuroscience 6, 101–102
(February 2003); doi:10.1038/nn0203-101
| Full Text (HTML/PDF) |
review article
Wnts and TGFβ in synaptogenesis: old friends signalling at new places
Mary Packard, Dennis Mathew and Vivian Budnik
Nature Reviews Neuroscience 4, 113–120
(February 2003); doi:10.1038/nrn1036
| Summary | Full Text (HTML / PDF) |
original paper
Type 1 insulin-like growth factor regulates MT1-MMP synthesis and tumor invasion via PI 3-kinase/Akt signaling
Donglei Zhang and Pnina Brodt
Oncogene 22, 974–982
(20 February 2003); doi:10.1038/sj.onc.1206197
| Abstract |
letters to nature
Auxin promotes Arabidopsis root growth by modulating gibberellin response
Xiangdong Fu and Nicholas P. Harberd
Nature 421, 740–743
(13 February 2003); doi:10.1038/nature01387
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letters to nature
Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain
Daniel J. Cua, Jonathan Sherlock, Yi Chen, Craig A. Murphy, Barbara Joyce, Brian Seymour, Linda Lucian, Wayne To, Sylvia Kwan, Tatyana Churakova, Sandra Zurawski, Maria Wiekowski, Sergio A. Lira, Daniel Gorman, Robert A. Kastelein and Jonathon D. Sedgwick
Nature 421, 744–748
(13 February 2003); doi:10.1038/nature01355
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news and views
Autoimmunity: A case of mistaken identity
Wendy T. Watford and John J. O'Shea
Nature 421, 706–708
(13 February 2003); doi:10.1038/421706a
| Full Text (HTML / PDF) |
letters to nature
Cdc42 regulates GSK-3β and adenomatous polyposis coli to control cell polarity
Sandrine Etienne-Manneville and Alan Hall
Nature 421, 753–756
(13 February 2003); doi:10.1038/nature01423
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letters to nature
Structure of the extracellular region of HER2 alone and in complex with the Herceptin Fab
Hyun-Soo Cho, Karen Mason, Kasra X. Ramyar, Ann Marie Stanley, Sandra B. Gabelli, Dan W. Denney Jr and Daniel J. Leahy
Nature 421, 756–760
(13 February 2003); doi:10.1038/nature01392
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article
The signal flow and motor response controling chemotaxis of sea urchin sperm
U. Benjamin Kaupp, Johannes Solzin, Eilo Hildebrand, Joel E. Brown, Annika Helbig, Volker Hagen, Michael Beyermann, Francesco Pampaloni and Ingo Weyand
Nature Cell Biology 5, 109–117
(February 2003); doi:10.1038/ncb915
| Abstract | Full Text (HTML/PDF) |
news and views
How to attract a sperm
Jackson C. Kirkman-Brown, Keith A. Sutton and Harvey M. Florman
Nature Cell Biology 5, 93–96
(February 2003); doi:10.1038/ncb0203-93
| Full Text (HTML/PDF) |
perspectives
Signalling pathways that mediate skeletal muscle hypertrophy and atrophy
David J. Glass
Nature Cell Biology 5, 87–90
(February 2003); doi:10.1038/ncb0203-87
| Full Text (HTML/PDF) |
review article
NALPs: a novel protein family involved in inflammation
Jürg Tschopp, Fabio Martinon and Kimberly Burns
Nature Reviews Molecular Cell Biology 4, 95–104
(February 2003); doi:10.1038/nrm1019
| Summary | Full Text (HTML / PDF) |
article
TICAM-1, an adaptor molecule that participates in Toll-like receptor 3-mediated interferon-β induction
Hiroyuki Oshiumi, Misako Matsumoto, Kenji Funami, Takashi Akazawa and Tsukasa Seya
Nature Immunology 4, 161–167
(February 2003); doi:10.1038/ni886
| Abstract | Full Text (HTML/PDF) |
news and views
Toll signaling: the TIReless quest for specificity
Jean-Luc Imler and Jules A. Hoffmann
Nature Immunology 4, 105–106
(February 2003); doi:10.1038/ni0203-105
| Full Text (HTML/PDF) |
review article
Adaptors as central mediators of signal transduction in immune cells
Martha S. Jordan, Andrew L. Singer and Gary A. Koretzky
Nature Immunology 4, 110–116
(February 2003); doi:10.1038/ni0203-110
| Abstract | Full Text (HTML/PDF) |
review article
Semaphorins in interactions between T cells and antigen-presenting cells
Hitoshi Kikutani and Atsushi Kumanogoh
Nature Reviews Immunology 3, 159–167
(February 2003); doi:10.1038/nri1003
| Summary | Full Text (HTML / PDF) |
article
Carbon monoxide suppresses arteriosclerotic lesions associated with chronic graft rejection and with balloon injury
Leo E. Otterbein, Brian S. Zuckerbraun, Manabu Haga, Fang Liu, Ruiping Song, Anny Usheva, Christina Stachulak, Natalya Bodyak, R. Neal Smith, Eva Csizmadia, Shivraj Tyagi, Yorihiro Akamatsu, Richard J. Flavell, Timothy R. Billiar, Edith Tzeng, Fritz H. Bach, Augustine M.K. Choi and Miguel P. Soares
Nature Medicine 9, 183–190
(February 2003); doi:10.1038/nm817
| Abstract | Full Text (HTML/PDF) |
article
The orphan nuclear receptor HNF4α determines PXR- and CAR-mediated xenobiotic induction of CYP3A4
Rommel G. Tirona, Wooin Lee, Brenda F. Leake, Lu-Bin Lan, Cynthia Brimer Cline, Vishal Lamba, Fereshteh Parviz, Stephen A. Duncan, Yusuke Inoue, Frank J. Gonzalez, Erin G. Schuetz and Richard B. Kim
Nature Medicine 9, 220–224
(February 2003); doi:10.1038/nm815
| Abstract | Full Text (HTML/PDF) |
review article
Coordinated regulation of life and death by RB
B. Nelson Chau and Jean Y.J. Wang
Nature Reviews Cancer 3, 130–138
(February 2003); doi:10.1038/nrc993
| Summary | Full Text (HTML / PDF) |
article
Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells
Surya M. Nauli, Francis J. Alenghat, Ying Luo, Eric Williams, Peter Vassilev, Xiaogang Li, Andrew E. H. Elia, Weining Lu, Edward M. Brown, Stephen J. Quinn, Donald E. Ingber and Jing Zhou
Nature Genetics 33, 129–137
(February 2003); doi:10.1038/ng1076
| Abstract | Full Text (HTML/PDF) |
news and views
Ciliary signaling goes down the tubes
James P. Calvet
Nature Genetics 33, 113–114
(February 2003); doi:10.1038/ng1078
| Full Text (HTML/PDF) |
article
Control of hippocampal dendritic spine morphology through ephrin-A3/EphA4 signaling
Keith K. Murai, Louis N. Nguyen, Fumitoshi Irie, Yu Yamaguchi and Elena B. Pasquale
Nature Neuroscience 6, 153–160
(February 2003); doi:10.1038/nn994
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news and views
Ephrins keep dendritic spines in shape
Scott M. Thompson
Nature Neuroscience 6, 103–104
(February 2003); doi:10.1038/nn0203-103
| Full Text (HTML/PDF) |
original paper
Nrf2 is an inhibitor of the Fas pathway as identified by Achilles' Heel Method, a new function-based approach to gene identification in human cells
Kumar U. Kotlo, Furma Yehiely, Elena Efimova, Heather Harasty, Bahar Hesabi, Ksenya Shchors, Paz Einat, Ada Rozen, Eva Berent and Louis P Deiss
Oncogene 22, 797–806
(13 February 2003); doi:10.1038/sj.onc.1206077
| Abstract |
letters to nature
Ankyrin-B mutation causes type 4 long-QT cardiac arrhythmia and sudden cardiac death
Peter J. Mohler, Jean-Jacques Schott, Anthony O. Gramolini, Keith W. Dilly, Silvia Guatimosim, William H. duBell, Long-Sheng Song, Karine Haurogné, Florence Kyndt, Mervat E. Ali, Terry B. Rogers, W. J. Lederer, Denis Escande, Herve Le Marec and Vann Bennett
Nature 421, 634–639
(06 February 2003); doi:10.1038/nature01335
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news and views
Human genetics: Lost anchors cost lives
Stanley Nattel
Nature 421, 587–590
(06 February 2003); doi:10.1038/421587a
| Full Text (HTML / PDF) |
letters to nature
NF-κB blockade and oncogenic Ras trigger invasive human epidermal neoplasia
Maya Dajee, Mirella Lazarov, Jennifer Y. Zhang, Ti Cai, Cheryl L. Green, Alan J. Russell, M. Peter Marinkovich, Shiying Tao, Qun Lin, Yoshiaki Kubo and Paul A. Khavari
Nature 421, 639–643
(06 February 2003); doi:10.1038/nature01283
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news and views
Cancer: More than skin deep
Diana Bolotin and Elaine Fuchs
Nature 421, 594–595
(06 February 2003); doi:10.1038/421594a
| Full Text (HTML / PDF) |
letters to nature
Telomere dysfunction and Atm deficiency compromises organ homeostasis and accelerates ageing
Kwok-Kin Wong, Richard S. Maser, Robert M. Bachoo, Jayant Menon, Daniel R. Carrasco, Yansong Gu, Frederick W. Alt and Ronald A. DePinho
Nature 421, 643–648
(06 February 2003); doi:10.1038/nature01385
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letters to nature
Structure and catalytic mechanism of the human histone methyltransferase SET7/9
Bing Xiao, Chun Jing, Jonathan R. Wilson, Philip A. Walker, Nishi Vasisht, Geoff Kelly, Steven Howell, Ian A. Taylor, G. Michael Blackburn and Steven J. Gamblin
Nature 421, 652–656
(06 February 2003); doi:10.1038/nature01378
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article
Fas engagement induces neurite growth through ERK activation and p35 upregulation
Julie Desbarats, Raymond B. Birge, Manuelle Mimouni-Rongy, David E. Weinstein, Jean-Sébastien Palerme and M. Karen Newell
Nature Cell Biology 5, 118–125
(February 2003); doi:10.1038/ncb916
| Abstract | Full Text (HTML/PDF) |
news and views
Killer wiles: growing interest in Fas
Brigitte Pettmann and Christopher E. Henderson
Nature Cell Biology 5, 91–92
(February 2003); doi:10.1038/ncb0203-91
| Full Text (HTML/PDF) |
letter
Binding of SAP SH2 domain to FynT SH3 domain reveals a novel mechanism of receptor signalling in immune regulation
Sylvain Latour, Romain Roncagalli, Riyan Chen, Marcin Bakinowski, Xiaochu Shi, Pamela L. Schwartzberg, Dominique Davidson and André Veillette
Nature Cell Biology 5, 149–154
(February 2003); doi:10.1038/ncb919
| First Paragraph | Full Text (HTML/PDF) |
review article
Tor signalling in bugs, brain and brawn
Estela Jacinto and Michael N. Hall
Nature Reviews Molecular Cell Biology 4, 117–126
(February 2003); doi:10.1038/nrm1018
| Summary | Full Text (HTML / PDF) |
article
LAB: A new membrane-associated adaptor molecule in B cell activation
Erin Janssen, Minghua Zhu, Weijia Zhang, Surapong Koonpaew and Weiguo Zhang
Nature Immunology 4, 117–123
(February 2003); doi:10.1038/ni882
| Abstract | Full Text (HTML/PDF) |
article
CTLA-4 regulates the requirement for cytokine-induced signals in TH2 lineage commitment
Hélène Bour-Jordan, Jane L. Grogan, Qizhi Tang, Julie A. Auger, Richard M. Locksley and Jeffrey A. Bluestone
Nature Immunology 4, 182–188
(February 2003); doi:10.1038/ni884
| Abstract | Full Text (HTML/PDF) |
review article
Interleukin-12 and the regulation of innate resistance and adaptive immunity
Giorgio Trinchieri
Nature Reviews Immunology 3, 133–146
(February 2003); doi:10.1038/nri1001
| Summary | Full Text (HTML / PDF) |
article
VEGF: A modifier of the del22q11 (DiGeorge) syndrome?
Ingeborg Stalmans, Diether Lambrechts, Frederik De smet, Sandra Jansen, Jian Wang, Sunit Maity, Paige Kneer, Maren von der Ohe, Ann Swillen, Christa Maes, Marc Gewillig, Daniel G.M. Molin, Peter Hellings, Thurid Boetel, Maartin Haardt, Veerle Compernolle, Mieke Dewerchin, Stephane Plaisance, Robert Vlietinck, Beverly Emanuel, Adriana C. Gittenberger-de Groot, Peter Scambler, Bernice Morrow, Deborah A. Driscol, Lieve Moons, Camila V. Esguerra, Geert Carmeliet, Annett Behn-Krappa, Koen Devriendt, Désiré Collen, Simon J. Conway and Peter Carmeliet
Nature Medicine 9, 173–182
(February 2003); doi:10.1038/nm819
| Abstract | Full Text (HTML/PDF) |
news and views
Splitting vessels: Keeping lymph apart from blood
Shahin Rafii and Mihaela Skobe
Nature Medicine 9, 166–168
(February 2003); doi:10.1038/nm0203-166
| Full Text (HTML/PDF) |
review article
Disruption of differentiation in human cancer: AML shows the way
Daniel G. Tenen
Nature Reviews Cancer 3, 89–101
(February 2003); doi:10.1038/nrc989
| Summary | Full Text (HTML / PDF) |
article
PKA phosphorylation of AMPA receptor subunits controls synaptic trafficking underlying plasticity
José A. Esteban, Song-Hai Shi, Christopher Wilson, Mutsuo Nuriya, Richard L. Huganir and Roberto Malinow
Nature Neuroscience 6, 136–143
(February 2003); doi:10.1038/nn997
| Abstract | Full Text (HTML/PDF) |
article
Activation of NR1/NR2B NMDA receptors
Tue G. Banke and Stephen F. Traynelis
Nature Neuroscience 6, 144–152
(February 2003); doi:10.1038/nn1000
| Abstract | Full Text (HTML/PDF) |
review article
The role of histamine and the tuberomamillary nucleus in the nervous system
Helmut Haas and Pertti Panula
Nature Reviews Neuroscience 4, 121–130
(February 2003); doi:10.1038/nrn1034
| Summary | Full Text (HTML / PDF) |
original paper
Bcl-xL and Akt cooperate to promote leukemogenesis in vivo
Robyn Karnauskas, Qun Niu, Sunit Talapatra, David R. Plas, Marianne E. Greene, John D. Crispino and Charles M. Rudin
Oncogene 22, 688–698
(6 February 2003); doi:10.1038/sj.onc.1206159
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