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The Research Library categorizes, and provides access to, all recent signaling-related research published in the Nature Publishing Group journals. The selection is deliberately broad to facilitate access to all research impacting on the signaling community. Both primary research and review articles are included, as are 'News and Views' articles.
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article
α-Neurexins couple Ca2+ channels to synaptic vesicle exocytosis
Markus Missler, Weiqi Zhang, Astrid Rohlmann, Gunnar Kattenstroth, Robert E. Hammer, Kurt Gottmann and Thomas C. Südhof
Nature 423, 939–948
(26 June 2003); doi:10.1038/nature01755
| Abstract | Full Text (HTML / PDF) |
news and views
Neurobiology: Synapses unplugged
J. Troy Littleton and Morgan Sheng
Nature 423, 931–932
(26 June 2003); doi:10.1038/423931a
| Full Text (HTML / PDF) |
article
Structure and gating mechanism of the acetylcholine receptor pore
Atsuo Miyazawa, Yoshinori Fujiyoshi and Nigel Unwin
Nature 423, 949–955
(26 June 2003); doi:10.1038/nature01748
| Abstract | Full Text (HTML / PDF) |
letters to nature
Cyclic AMP/GMP-dependent modulation of Ca2+ channels sets the polarity of nerve growth-cone turning
Makoto Nishiyama, Akemi Hoshino, Lily Tsai, John R. Henley, Yoshio Goshima, Marc Tessier-Lavigne, Mu-ming Poo and Kyonsoo Hong
Nature 423, 990–995
(26 June 2003); doi:10.1038/nature01751
| First Paragraph | Full Text (HTML / PDF) |
letters to nature
LAF1 ubiquitination by COP1 controls photomorphogenesis and is stimulated by SPA1
Hak Soo Seo, Jun-Yi Yang, Masaki Ishikawa, Cordelia Bolle, Maria L. Ballesteros and Nam-Hai Chua
Nature 423, 995–999
(26 June 2003); doi:10.1038/nature01696
| First Paragraph | Full Text (HTML / PDF) |
letters to nature
Enhanced gravi- and phototropism in plant mdr mutants mislocalizing the auxin efflux protein PIN1
Bosl Noh, Anindita Bandyopadhyay, Wendy Ann Peer, Edgar P. Spalding and Angus S. Murphy
Nature 423, 999–1002
(26 June 2003); doi:10.1038/nature01716
| First Paragraph | Full Text (HTML / PDF) |
letters to nature
Chromosome cohesion is regulated by a clock gene paralogue TIM-1
Raymond C. Chan, Annette Chan, Mili Jeon, Tammy F. Wu, Danielle Pasqualone, Ann E. Rougvie and Barbara J. Meyer
Nature 423, 1002–1009
(26 June 2003); doi:10.1038/nature01697
| First Paragraph | Full Text (HTML / PDF) |
letters to nature
Cks1-dependent proteasome recruitment and activation of CDC20 transcription in budding yeast
May C. Morris, Peter Kaiser, Stanislav Rudyak, Chris Baskerville, Mark H. Watson and Steven I. Reed
Nature 423, 1009–1013
(26 June 2003); doi:10.1038/nature01720
| First Paragraph | Full Text (HTML / PDF) |
letter
Dual phosphorylation controls Cdc25 phosphatases and mitotic entry
Dmitry V. Bulavin, Yuichiro Higashimoto, Zoya N. Demidenko, Sarah Meek, Paul Graves, Crissy Phillips, Hui Zhao, Sally A. Moody, Ettore Appella, Helen Piwnica-Worms and Albert J. Fornace Jr
Nature Cell Biology 5, 545–551
(June 2003); doi:10.1038/ncb994
| First Paragraph | Full Text (HTML/PDF) |
letter
Differential regulation of E2F1 apoptotic target genes in response to DNA damage
Natalia Pediconi, Alessandra Ianari, Antonio Costanzo, Laura Belloni, Rita Gallo, Letizia Cimino, Antonio Porcellini, Isabella Screpanti, Clara Balsano, Edoardo Alesse, Alberto Gulino and Massimo Levrero
Nature Cell Biology 5, 552–558
(June 2003); doi:10.1038/ncb998
| First Paragraph | Full Text (HTML/PDF) |
news and views
The cutting edge of mitochondrial fusion
Michael P. Yaffe
Nature Cell Biology 5, 497–499
(June 2003); doi:10.1038/ncb0603-497b
| Full Text (HTML/PDF) |
review article
Fibulins: a versatile family of extracellular matrix proteins
Rupert Timpl, Takako Sasaki, Günter Kostka and Mon-Li Chu
Nature Reviews Molecular Cell Biology 4, 479–489
(June 2003); doi:10.1038/nrm1130
| Summary | Full Text (HTML / PDF) |
article
Bcl11a is essential for normal lymphoid development
Pentao Liu, Jonathan R Keller, Mariaestela Ortiz, Lino Tessarollo, Rivka A Rachel, Takuro Nakamura, Nancy A Jenkins and Neal G Copeland
Nature Immunology 4, 525–532
(June 2003); doi:10.1038/ni925
| Abstract | Full Text (HTML/PDF) |
article
Bcl11b is required for differentiation and survival of αβ T lymphocytes
Yuichi Wakabayashi, Hisami Watanabe, Jun Inoue, Naoki Takeda, Jun Sakata, Yukio Mishima, Jiro Hitomi, Takashi Yamamoto, Masanori Utsuyama, Ohtsura Niwa, Shinichi Aizawa and Ryo Kominami
Nature Immunology 4, 533–539
(June 2003); doi:10.1038/ni927
| Abstract | Full Text (HTML/PDF) |
news and views
Bcl11: sibling rivalry in lymphoid development
Scott K Durum
Nature Immunology 4, 512–514
(June 2003); doi:10.1038/ni0603-512
| Full Text (HTML/PDF) |
review article
The TIM gene family: emerging roles in immunity and disease
Vijay K. Kuchroo, Dale T. Umetsu, Rosemarie H. DeKruyff and Gordon J. Freeman
Nature Reviews Immunology 3, 454–462
(June 2003); doi:10.1038/nri1111
| Summary | Full Text (HTML / PDF) |
article
Attenuation of levodopa-induced dyskinesia by normalizing dopamine D3 receptor function
Erwan Bézard, Sandrine Ferry, Ulrich Mach, Holger Stark, Ludovic Leriche, Thomas Boraud, Christian Gross and Pierre Sokoloff
Nature Medicine 9, 762–767
(June 2003); doi:10.1038/nm875
| Abstract | Full Text (HTML/PDF) |
article
Leukocytes mediate retinal vascular remodeling during development and vaso-obliteration in disease
Susumu Ishida, Kenji Yamashiro, Tomohiko Usui, Yuichi Kaji, Yuichiro Ogura, Tetsuo Hida, Yoshihito Honda, Yoshihisa Oguchi and Anthony P Adamis
Nature Medicine 9, 781–788
(June 2003); doi:10.1038/nm877
| Abstract | Full Text (HTML/PDF) |
review article
Angiogenesis in health and disease
Peter Carmeliet
Nature Medicine 9, 653–660
(June 2003); doi:10.1038/nm0603-653
| Abstract | Full Text (HTML/PDF) |
review article
Molecular regulation of vessel maturation
Rakesh K Jain
Nature Medicine 9, 685–693
(June 2003); doi:10.1038/nm0603-685
| Abstract | Full Text (HTML/PDF) |
review article
Gene transfer as a tool to induce therapeutic vascular growth
Seppo Ylä-Herttuala and Kari Alitalo
Nature Medicine 9, 694–701
(June 2003); doi:10.1038/nm0603-694
| Abstract | Full Text (HTML/PDF) |
review article
Vasculogenic mimicry and tumour-cell plasticity: lessons from melanoma
Mary J. C. Hendrix, Elisabeth A. Seftor, Angela R. Hess and Richard E. B. Seftor
Nature Reviews Cancer 3, 411–421
(June 2003); doi:10.1038/nrc1092
| Summary | Full Text (HTML / PDF) |
perspectives
RAS oncogenes: the first 30 years
Marcos Malumbres and Mariano Barbacid
Nature Reviews Cancer 3, 459–465
(June 2003); doi:10.1038/nrc1097
| Summary | Full Text (HTML / PDF) |
letter
Trans allele methylation and paramutation-like effects in mice
Herry Herman, Michael Lu, Melly Anggraini, Aimee Sikora, Yanjie Chang, Bong June Yoon and Paul D Soloway
Nature Genetics 34, 199–202
(June 2003); doi:10.1038/ng1162
| First Paragraph | Full Text (HTML/PDF) |
review article
Extracellular matrix molecules and synaptic plasticity
Alexander Dityatev and Melitta Schachner
Nature Reviews Neuroscience 4, 456–468
(June 2003); doi:10.1038/nrn1115
| Summary | Full Text (HTML / PDF) |
article
Structural insights into the catalytic mechanism of cyclophilin A
Bruce R Howard, Felix F Vajdos, Su Li, Wesley I Sundquist and Christopher P Hill
Nature Structural Biology 10, 475–481
(June 2003); doi:10.1038/nsb927
| Abstract | Full Text (HTML/PDF) |
review article
Therapeutic strategies for rheumatoid arthritis
Josef S. Smolen and Günter Steiner
Nature Reviews Drug Discovery 2, 473–488
(June 2003); doi:10.1038/nrd1109
| Summary | Full Text (HTML / PDF) |
letters to nature
Involvement of Notch and Delta genes in spider segmentation
Angelika Stollewerk, Michael Schoppmeier and Wim G. M. Damen
Nature 423, 863–865
(19 June 2003); doi:10.1038/nature01682
| First Paragraph | Full Text (HTML / PDF) |
letters to nature
Fibronectin requirement in branching morphogenesis
Takayoshi Sakai, Melinda Larsen and Kenneth M. Yamada
Nature 423, 876–881
(19 June 2003); doi:10.1038/nature01712
| First Paragraph | Full Text (HTML / PDF) |
letters to nature
Regulation of flowering time by light quality
Pablo D. Cerdán and Joanne Chory
Nature 423, 881–885
(19 June 2003); doi:10.1038/nature01636
| First Paragraph | Full Text (HTML / PDF) |
letters to nature
CUL-4 ubiquitin ligase maintains genome stability by restraining DNA-replication licensing
Weiwei Zhong, Hui Feng, Fernando E. Santiago and Edward T. Kipreos
Nature 423, 885–889
(19 June 2003); doi:10.1038/nature01747
| First Paragraph | Full Text (HTML / PDF) |
news and views
Cell cycle: Degradation ensures integrity
Anatoliy Li and J. Julian Blow
Nature 423, 818–819
(19 June 2003); doi:10.1038/423818b
| Full Text (HTML / PDF) |
letter
Rheb is an essential regulator of S6K in controlling cell growth in Drosophila
Hugo Stocker, Thomas Radimerski, Benno Schindelholz, Franz Wittwer, Priyanka Belawat, Pierre Daram, Sebastian Breuer, George Thomas and Ernst Hafen
Nature Cell Biology 5, 559–566
(June 2003); doi:10.1038/ncb995
| First Paragraph | Full Text (HTML/PDF) |
letter
Rheb promotes cell growth as a component of the insulin/TOR signalling network
Leslie J. Saucedo, Xinsheng Gao, Dominic A. Chiarelli, Ling Li, Duoija Pan and Bruce A. Edgar
Nature Cell Biology 5, 566–571
(June 2003); doi:10.1038/ncb996
| First Paragraph | Full Text (HTML/PDF) |
brief communication
Rheb is a direct target of the tuberous sclerosis tumour suppressor proteins
Yong Zhang, Xinsheng Gao, Leslie J. Saucedo, Binggen Ru, Bruce A. Edgar and Duojia Pan
Nature Cell Biology 5, 578–581
(June 2003); doi:10.1038/ncb999
| First Paragraph | Full Text (HTML/PDF) |
news and views
Meddling with methylation
Chih-Lin Hsieh and Peter A. Jones
Nature Cell Biology 5, 502–504
(June 2003); doi:10.1038/ncb0603-502
| Full Text (HTML/PDF) |
review article
Molecular views of recombination proteins and their control
Stephen C. West
Nature Reviews Molecular Cell Biology 4, 435–445
(June 2003); doi:10.1038/nrm1127
| Summary | Full Text (HTML / PDF) |
article
NKG2D-DAP10 triggers human NK cell-mediated killing via a Syk-independent regulatory pathway
Daniel D Billadeau, Jadee L Upshaw, Renee A Schoon, Christopher J Dick and Paul J Leibson
Nature Immunology 4, 557–564
(June 2003); doi:10.1038/ni929
| Abstract | Full Text (HTML/PDF) |
article
NKG2D triggers cytotoxicity in mouse NK cells lacking DAP12 or Syk family kinases
Simona Zompi, Jessica A Hamerman, Kouetsu Ogasawara, Edina Schweighoffer, Victor L J Tybulewicz, James P Di Santo, Lewis L Lanier and Francesco Colucci
Nature Immunology 4, 565–572
(June 2003); doi:10.1038/ni930
| Abstract | Full Text (HTML/PDF) |
news and views
The choices of a natural killer
Giorgio Trinchieri
Nature Immunology 4, 509–510
(June 2003); doi:10.1038/ni0603-509
| Full Text (HTML/PDF) |
article
Prostaglandin E2-EP4 signaling initiates skin immune responses by promoting migration and maturation of Langerhans cells
Kenji Kabashima, Daiji Sakata, Miyako Nagamachi, Yoshiki Miyachi, Kayo Inaba and Shuh Narumiya
Nature Medicine 9, 744–749
(June 2003); doi:10.1038/nm872
| Abstract | Full Text (HTML/PDF) |
letter
Targeting exogenous genes to tumor angiogenesis by transplantation of genetically modified hematopoietic stem cells
Michele De Palma, Mary Anna Venneri, Cristina Roca and Luigi Naldini
Nature Medicine 9, 789–795
(June 2003); doi:10.1038/nm871
| First Paragraph | Full Text (HTML/PDF) |
review article
Endothelial signaling during development
Ondine Cleaver and Douglas A Melton
Nature Medicine 9, 661–668
(June 2003); doi:10.1038/nm0603-661
| Abstract | Full Text (HTML/PDF) |
review article
Regulation of angiogenesis by hypoxia: role of the HIF system
Christopher W Pugh and Peter J Ratcliffe
Nature Medicine 9, 677–684
(June 2003); doi:10.1038/nm0603-677
| Abstract | Full Text (HTML/PDF) |
review article
Angiogenesis: Tumorigenesis and the angiogenic switch
Gabriele Bergers and Laura E. Benjamin
Nature Reviews Cancer 3, 401–410
(June 2003); doi:10.1038/nrc1093
| Summary | Full Text (HTML / PDF) |
review article
Stem-cell hierarchy in skin cancer
Jesus Perez-Losada and Allan Balmain
Nature Reviews Cancer 3, 434–443
(June 2003); doi:10.1038/nrc1095
| Summary | Full Text (HTML / PDF) |
review article
Reelin and brain development
Fadel Tissir and André M. Goffinet
Nature Reviews Neuroscience 4, 496–505
(June 2003); doi:10.1038/nrn1113
| Summary | Full Text (HTML / PDF) |
article
Regulation of neuronal SNARE assembly by the membrane
Dae-Hyuk Kweon, Chang Sup Kim and Yeon-Kyun Shin
Nature Structural Biology 10, 440–447
(June 2003); doi:10.1038/nsb928
| Abstract | Full Text (HTML/PDF) |
news and views
SNARE function revisited
Josep Rizo
Nature Structural Biology 10, 417–419
(June 2003); doi:10.1038/nsb0603-417
| Full Text (HTML/PDF) |
research article
Discovering potent and selective reversible inhibitors of enzymes in complex proteomes
Donmienne Leung, Christophe Hardouin, Dale L Boger and Benjamin F Cravatt
Nature Biotechnology 21, 687–691
(June 2003); doi:10.1038/nbt826
| First Paragraph | Full Text (HTML/PDF) |
article
Functional proteomic identification of DNA replication proteins by induced proteolysis in vivo
Masato Kanemaki, Alberto Sanchez-Diaz, Agnieszka Gambus and Karim Labib
Nature 423, 720–725
(12 June 2003); doi:10.1038/nature01692
| Abstract | Full Text (HTML / PDF) |
letters to nature
Control of dynamic CFTR selectivity by glutamate and ATP in epithelial cells
M. M. Reddy and P. M. Quinton
Nature 423, 756–760
(12 June 2003); doi:10.1038/nature01694
| First Paragraph | Full Text (HTML / PDF) |
letters to nature
Cloning of adiponectin receptors that mediate antidiabetic metabolic effects
Toshimasa Yamauchi, Junji Kamon, Yusuke Ito, Atsushi Tsuchida, Takehiko Yokomizo, Shunbun Kita, Takuya Sugiyama, Makoto Miyagishi, Kazuo Hara, Masaki Tsunoda, Koji Murakami, Toshiaki Ohteki, Shoko Uchida, Sato Takekawa, Hironori Waki, Nelson H. Tsuno, Yoichi Shibata, Yasuo Terauchi, Philippe Froguel, Kazuyuki Tobe, Shigeo Koyasu, Kazunari Taira, Toshio Kitamura, Takao Shimizu, Ryozo Nagai and Takashi Kadowaki
Nature 423, 762–769
(12 June 2003); doi:10.1038/nature01705
| First Paragraph | Full Text (HTML / PDF) |
letters to nature
Redox regulation of protein tyrosine phosphatase 1B involves a sulphenyl-amide intermediate
Annette Salmeen, Jannik N. Andersen, Michael P. Myers, Tzu-Ching Meng, John A. Hinks, Nicholas K. Tonks and David Barford
Nature 423, 769–773
(12 June 2003); doi:10.1038/nature01680
| First Paragraph | Full Text (HTML / PDF) |
letters to nature
Oxidation state of the active-site cysteine in protein tyrosine phosphatase 1B
Rob L. M. van Montfort, Miles Congreve, Dominic Tisi, Robin Carr and Harren Jhoti
Nature 423, 773–777
(12 June 2003); doi:10.1038/nature01681
| First Paragraph | Full Text (HTML / PDF) |
article
NMDA receptor trafficking through an interaction between PDZ proteins and the exocyst complex
Nathalie Sans, Kate Prybylowski, Ronald S. Petralia, Kai Chang, Ya-Xian Wang, Claudia Racca, Stefano Vicini and Robert J. Wenthold
Nature Cell Biology 5, 520–530
(June 2003); doi:10.1038/ncb990
| Abstract | Full Text (HTML/PDF) |
news and views
The return of the exocyst
Casper C. Hoogenraad and Morgan Sheng
Nature Cell Biology 5, 493–495
(June 2003); doi:10.1038/ncb0603-493
| Full Text (HTML/PDF) |
letter
Syntaxin specificity of cytokinesis in Arabidopsis
Isabel Müller, Wenke Wagner, Axel Völker, Swen Schellmann, Philippe Nacry, Frank Küttner, Zsuzsanna Schwarz-Sommer, Ulrike Mayer and Gerd Jürgens
Nature Cell Biology 5, 531–534
(June 2003); doi:10.1038/ncb991
| First Paragraph | Full Text (HTML/PDF) |
perspectives
When ubiquitin meets ubiquitin receptors: a signalling connection
Pier Paolo Di Fiore , Simona Polo and Kay Hofmann
Nature Reviews Molecular Cell Biology 4, 491–497
(June 2003); doi:10.1038/nrm1124
| Summary | Full Text (HTML / PDF) |
article
Subversion of the innate immune system by a retrovirus
Brooke A Jude, Yelena Pobezinskaya, Jennifer Bishop, Susannah Parke, Ruslan M Medzhitov, Alexander V Chervonsky and Tatyana V Golovkina
Nature Immunology 4, 573–578
(June 2003); doi:10.1038/ni926
| Abstract | Full Text (HTML/PDF) |
article
E-proteins directly regulate expression of activation-induced deaminase in mature B cells
Camil Elie Sayegh, Melanie W Quong, Yasutoshi Agata and Cornelis Murre
Nature Immunology 4, 586–593
(June 2003); doi:10.1038/ni923
| Abstract | Full Text (HTML/PDF) |
article
Resistance to CpG DNA-induced autoimmunity through tolerogenic B cell antigen receptor ERK signaling
Lixin Rui, Carola G Vinuesa, Julie Blasioli and Christopher C Goodnow
Nature Immunology 4, 594–600
(June 2003); doi:10.1038/ni924
| Abstract | Full Text (HTML/PDF) |
news and views
Manipulating hematopoietic stem cell amplification with Wnt
Connie J Eaves PhD
Nature Immunology 4, 511–512
(June 2003); doi:10.1038/ni0603-511
| Full Text (HTML/PDF) |
article
A nonpeptidyl mimic of superoxide dismutase, M40403, inhibits dose-limiting hypotension associated with interleukin-2 and increases its antitumor effects
Wolfram E Samlowski, Ryan Petersen, Salvatore Cuzzocrea, Heather Macarthur, Damali Burton, John R McGregor and Daniela Salvemini
Nature Medicine 9, 750–755
(June 2003); doi:10.1038/nm874
| Abstract | Full Text (HTML/PDF) |
news and views
Biological drug duo delivers one-two tumor punch
Jeffrey A Sosman and James W Mier
Nature Medicine 9, 649–650
(June 2003); doi:10.1038/nm0603-649
| Full Text (HTML/PDF) |
review article
The biology of VEGF and its receptors
Napoleone Ferrara, Hans-Peter Gerber and Jennifer LeCouter
Nature Medicine 9, 669–676
(June 2003); doi:10.1038/nm0603-669
| Abstract | Full Text (HTML/PDF) |
review article
Contribution of stem cells and differentiated cells to epidermal tumours
David M. Owens and Fiona M. Watt
Nature Reviews Cancer 3, 444–451
(June 2003); doi:10.1038/nrc1096
| Summary | Full Text (HTML / PDF) |
letter
Gene expression phenotypic models that predict the activity of oncogenic pathways
Erich Huang, Seiichi Ishida, Jennifer Pittman, Holly Dressman, Andrea Bild, Mark Kloos, Mark D'Amico, Richard G Pestell, Mike West and Joseph R Nevins
Nature Genetics 34, 226–230
(June 2003); doi:10.1038/ng1167
| First Paragraph | Full Text (HTML/PDF) |
review article
When calcium goes wrong: genetic alterations of a ubiquitous signaling route
Rosario Rizzuto and Tullio Pozzan
Nature Genetics 34, 135–141
(June 2003); doi:10.1038/ng0603-135
| Abstract | Full Text (HTML/PDF) |
article
A new phospholipid phosphatase, PRG-1, is involved in axon growth and regenerative sprouting
Anja U Bräuer, Nicolai E Savaskan, Hartmut Kühn, Siegfried Prehn, Olaf Ninnemann and Robert Nitsch
Nature Neuroscience 6, 572–578
(June 2003); doi:10.1038/nn1052
| Abstract | Full Text (HTML/PDF) |
brief communication
Activity-dependent activation of presynaptic protein kinase C mediates post-tetanic potentiation
Darrin H Brager, Xiang Cai and Scott M Thompson
Nature Neuroscience 6, 551–552
(June 2003); doi:10.1038/nn1067
| First Paragraph | Full Text (HTML/PDF) |
review article
Chemokine receptors: signposts to brain development and disease
Phuong B. Tran and Richard J. Miller
Nature Reviews Neuroscience 4, 444–455
(June 2003); doi:10.1038/nrn1116
| Summary | Full Text (HTML / PDF) |
article
Redox-sensitive extracellular gates formed by auxiliary b subunits of calcium-activated potassium channels
Xu-Hui Zeng, Xiao-Ming Xia and Christopher J Lingle
Nature Structural Biology 10, 448–454
(June 2003); doi:10.1038/nsb932
| Abstract | Full Text (HTML/PDF) |
research article
Global protein function prediction from protein-protein interaction networks
Alexei Vazquez, Alessandro Flammini, Amos Maritan and Alessandro Vespignani
Nature Biotechnology 21, 697–700
(June 2003); doi:10.1038/nbt825
| First Paragraph | Full Text (HTML/PDF) |
review article
Ophthalmic drug discovery
Abbot F. Clark and Thomas Yorio
Nature Reviews Drug Discovery 2, 448–459
(June 2003); doi:10.1038/nrd1106
| Summary | Full Text (HTML / PDF) |
article
Three modes of synaptic vesicular recycling revealed by single-vesicle imaging
Sunil P. Gandhi and Charles F. Stevens
Nature 423, 607–613
(05 June 2003); doi:10.1038/nature01677
| Abstract | Full Text (HTML / PDF) |
letters to nature
Single synaptic vesicles fusing transiently and successively without loss of identity
A. M. Aravanis , J. L. Pyle and R. W. Tsien
Nature 423, 643–647
(05 June 2003); doi:10.1038/nature01686
| First Paragraph | Full Text (HTML / PDF) |
news and views
Neurobiology: All change at the synapse
Silvio O. Rizzoli and William J. Betz
Nature 423, 591–592
(05 June 2003); doi:10.1038/423591a
| Full Text (HTML / PDF) |
article
Insights into IgA-mediated immune responses from the crystal structures of human FcαRI and its complex with IgA1-Fc
Andrew B. Herr, Edward R. Ballister and Pamela J. Bjorkman
Nature 423, 614–620
(05 June 2003); doi:10.1038/nature01685
| Abstract | Full Text (HTML / PDF) |
letters to nature
Fission yeast mod5p regulates polarized growth through anchoring of tea1p at cell tips
Hilary A. Snaith and Kenneth E. Sawin
Nature 423, 647–651
(05 June 2003); doi:10.1038/nature01672
| First Paragraph | Full Text (HTML / PDF) |
letters to nature
Sphingolipid signalling in Arabidopsis guard cells involves heterotrimeric G proteins
Sylvie Coursol , Liu-Min Fan, Hervé Le Stunff, Sarah Spiegel, Simon Gilroy and Sarah M. Assmann
Nature 423, 651–654
(05 June 2003); doi:10.1038/nature01643
| First Paragraph | Full Text (HTML / PDF) |
letters to nature
Histone H3 phosphorylation by IKK-α is critical for cytokine-induced gene expression
Yumi Yamamoto, Udit N. Verma, Shashi Prajapati, Youn-Tae Kwak and Richard B. Gaynor
Nature 423, 655–659
(05 June 2003); doi:10.1038/nature01576
| First Paragraph | Full Text (HTML / PDF) |
letters to nature
A nucleosomal function for IκB kinase-α in NF-κB-dependent gene expression
Vasiliki Anest, Julie L. Hanson, Patricia C. Cogswell, Kris A. Steinbrecher, Brian D. Strahl and Albert S. Baldwin
Nature 423, 659–663
(05 June 2003); doi:10.1038/nature01648
| First Paragraph | Full Text (HTML / PDF) |
news and views
Signal transduction: A regulator branches out
Alain Israël
Nature 423, 596–597
(05 June 2003); doi:10.1038/423596a
| Full Text (HTML / PDF) |
news and views
Cancer: Out of air is not out of action
Donald P. Bottaro and Lance A. Liotta
Nature 423, 593–595
(05 June 2003); doi:10.1038/423593a
| Full Text (HTML / PDF) |
article
MKP3 mediates the cellular response to FGF8 signalling in the vertebrate limb
Yasuhiko Kawakami, Joaquín Rodríguez-León, Christopher M. Koth, Dirk Büscher, Tohru Itoh, Ángel Raya, Jennifer K. Ng, Concepción Rodríguez Esteban, Shigeru Takahashi, Domingos Henrique, May-Fun Schwarz, Hiroshi Asahara and Juan Carlos Izpisúa Belmonte
Nature Cell Biology 5, 513–519
(June 2003); doi:10.1038/ncb989
| Abstract | Full Text (HTML/PDF) |
news and views
Deconstructing phosphatases in limb development
Andrew T. Dudley and Clifford J. Tabin
Nature Cell Biology 5, 499–501
(June 2003); doi:10.1038/ncb0603-499
| Full Text (HTML/PDF) |
news and views
IKKα: a chromatin modifier
Sowmya Swaminathan
Nature Cell Biology 5, 503
(June 2003); doi:10.1038/ncb0603-503
| Full Text (HTML/PDF) |
review article
ROCKs: multifunctional kinases in cell behaviour
Kirsi Riento and Anne J. Ridley
Nature Reviews Molecular Cell Biology 4, 446–456
(June 2003); doi:10.1038/nrm1128
| Summary | Full Text (HTML / PDF) |
article
SOCS3 negatively regulates IL-6 signaling in vivo
Ben A Croker, Danielle L Krebs, Jian-Guo Zhang, Sam Wormald, Tracy A Willson, Edouard G Stanley, Lorraine Robb, Christopher J Greenhalgh, Irmgard Förster, Björn E Clausen, Nicos A Nicola, Donald Metcalf, Douglas J Hilton, Andrew W Roberts and Warren S Alexander
Nature Immunology 4, 540–545
(June 2003); doi:10.1038/ni931
| Abstract | Full Text (HTML/PDF) |
article
SOCS3 regulates the plasticity of gp130 signaling
Roland Lang, Anne-Laure Pauleau, Evan Parganas, Yutaka Takahashi, Jörg Mages, James N Ihle, Robert Rutschman and Peter J Murray
Nature Immunology 4, 546–550
(June 2003); doi:10.1038/ni932
| Abstract | Full Text (HTML/PDF) |
article
IL-6 induces an anti-inflammatory response in the absence of SOCS3 in macrophages
Hideo Yasukawa, Masanobu Ohishi, Hiroyuki Mori, Masaaki Murakami, Takatoshi Chinen, Daisuke Aki, Toshikatsu Hanada, Kiyoshi Takeda, Shizuo Akira, Masahiko Hoshijima, Toshio Hirano, Kenneth R Chien and Akihiko Yoshimura
Nature Immunology 4, 551–556
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Matching SOCS with function
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Nature Immunology 4, 507–509
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TREMs in the immune system and beyond
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Nature Reviews Immunology 3, 445–453
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Pigment epithelium-derived factor regulates the vasculature and mass of the prostate and pancreas
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Nature Medicine 9, 774–780
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Nature Reviews Cancer 3, 422–433
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Module networks: identifying regulatory modules and their condition-specific regulators from gene expression data
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Nature Genetics 34, 166–176
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Roles and rules of kainate receptors in synaptic transmission
Juan Lerma
Nature Reviews Neuroscience 4, 481–495
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AKAP150 signaling complex promotes suppression of the M-current by muscarinic agonists
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Predicting therapeutic value in the lead optimization phase of drug discovery
Terry Kenakin
Nature Reviews Drug Discovery 2, 429–438
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