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The Research Library categorizes, and provides access to, all recent signaling-related research published in the Nature Publishing Group journals. The selection is deliberately broad to facilitate access to all research impacting on the signaling community. Both primary research and review articles are included, as are 'News and Views' articles.
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article
Class 3 semaphorins control vascular morphogenesis by inhibiting integrin function
Guido Serini, Donatella Valdembri, Sara Zanivan, Giulia Morterra, Constanze Burkhardt, Francesca Caccavari, Luca Zammataro, Luca Primo, Luca Tamagnone, Malcolm Logan, Marc Tessier-Lavigne, Masahiko Taniguchi, Andreas W. Püschel and Federico Bussolino
Nature 424, 391–397
(24 July 2003); doi:10.1038/nature01784
| Abstract | Full Text (HTML / PDF) |
article
Semaphorin 7A promotes axon outgrowth through integrins and MAPKs
R. Jeroen Pasterkamp, Jacques J. Peschon, Melanie K. Spriggs and Alex L. Kolodkin
Nature 424, 398–405
(24 July 2003); doi:10.1038/nature01790
| Abstract | Full Text (HTML / PDF) |
news and views
Neurobiology: A new way to network
Patrick Mehlen
Nature 424, 381–382
(24 July 2003); doi:10.1038/424381a
| Full Text (HTML / PDF) |
letters to nature
Anandamide and arachidonic acid use epoxyeicosatrienoic acids to activate TRPV4 channels
Hiroyuki Watanabe, Joris Vriens, Jean Prenen, Guy Droogmans, Thomas Voets and Bernd Nilius
Nature 424, 434–438
(24 July 2003); doi:10.1038/nature01807
| First Paragraph | Full Text (HTML / PDF) |
letters to nature
GATA4 mutations cause human congenital heart defects and reveal an interaction with TBX5
Vidu Garg, Irfan S. Kathiriya , Robert Barnes, Marie K. Schluterman, Isabelle N. King, Cheryl A. Butler, Caryn R. Rothrock, Reenu S. Eapen, Kayoko Hirayama-Yamada, Kunitaka Joo, Rumiko Matsuoka, Jonathan C. Cohen and Deepak Srivastava
Nature 424, 443–447
(24 July 2003); doi:10.1038/nature01827
| First Paragraph | Full Text (HTML / PDF) |
letters to nature
The molecular nature of the zebrafish tail organizer
Antoine Agathon, Christine Thisse and Bernard Thisse
Nature 424, 448–452
(24 July 2003); doi:10.1038/nature01822
| First Paragraph | Full Text (HTML / PDF) |
news and views
Developmental biology: A tale of tails
Christof Niehrs
Nature 424, 375–376
(24 July 2003); doi:10.1038/424375a
| Full Text (HTML / PDF) |
letters to nature
WAVE2 is required for directed cell migration and cardiovascular development
Daisuke Yamazaki, Shiro Suetsugu, Hiroaki Miki, Yuki Kataoka, Shin-Ichi Nishikawa, Takashi Fujiwara, Nobuaki Yoshida and Tadaomi Takenawa
Nature 424, 452–456
(24 July 2003); doi:10.1038/nature01770
| First Paragraph | Full Text (HTML / PDF) |
letters to nature
Epidermal growth factor receptor is a cellular receptor for human cytomegalovirus
Xin Wang, Shu-Mei Huong, Marie L. Chiu, Nancy Raab-Traub and Eng-Shang Huang
Nature 424, 456–461
(24 July 2003); doi:10.1038/nature01818
| First Paragraph | Full Text (HTML / PDF) |
letters to nature
RhoG activates Rac1 by direct interaction with the Dock180-binding protein Elmo
Hironori Katoh and Manabu Negishi
Nature 424, 461–464
(24 July 2003); doi:10.1038/nature01817
| First Paragraph | Full Text (HTML / PDF) |
letters to nature
Crystal structure of human cytochrome P450 2C9 with bound warfarin
Pamela A. Williams, Jose Cosme, Alison Ward, Hayley C. Angove, Dijana Matak Vinkovic and Harren Jhoti
Nature 424, 464–468
(24 July 2003); doi:10.1038/nature01862
| First Paragraph | Full Text (HTML / PDF) |
news and views
Developmental biology: Boundary lines
Seth S. Blair
Nature 424, 379–381
(24 July 2003); doi:10.1038/424379a
| Full Text (HTML / PDF) |
letter
Crosstalk between Rap1 and Rac regulates secretion of sAPPα
Marjorie Maillet, Sylvain J. Robert, Mathias Cacquevel, Monique Gastineau, Denis Vivien, Jacques Bertoglio, José L. Zugaza, Rodolphe Fischmeister and Frank Lezoualc'h
Nature Cell Biology 5, 633–639
(July 2003); doi:10.1038/ncb1007
| First Paragraph | Full Text (HTML/PDF) |
letter
Histone H2AX phosphorylation is dispensable for the initial recognition of DNA breaks
Arkady Celeste, Oscar Fernandez-Capetillo, Michael J. Kruhlak, Duane R. Pilch, David W. Staudt, Alicia Lee, Robert F. Bonner, William M. Bonner and André Nussenzweig
Nature Cell Biology 5, 675–679
(July 2003); doi:10.1038/ncb1004
| First Paragraph | Full Text (HTML/PDF) |
news and views
Movin' on through with Cdc2
Rudy Juliano
Nature Cell Biology 5, 589–590
(July 2003); doi:10.1038/ncb0703-589
| Full Text (HTML/PDF) |
review article
Conserved microtubule-actin interactions in cell movement and morphogenesis
Olga C. Rodriguez, Andrew W. Schaefer, Craig A. Mandato, Paul Forscher, William M. Bement and Clare M. Waterman-Storer
Nature Cell Biology 5, 599–609
(July 2003); doi:10.1038/ncb0703-599
| Abstract | Full Text (HTML/PDF) |
review article
Phospholamban: a crucial regulator of cardiac contractility
David H. MacLennan and Evangelia G. Kranias
Nature Reviews Molecular Cell Biology 4, 566–577
(July 2003); doi:10.1038/nrm1151
| Abstract | Full Text (HTML / PDF) |
perspectives
Timeline: 20 years of Ins(1,4,5)P3, and 40 years before
Robin F. Irvine
Nature Reviews Molecular Cell Biology 4, 580–585
(July 2003); doi:10.1038/nrm1152
| Abstract | Full Text (HTML / PDF) |
article
CpG directly induces T-bet expression and inhibits IgG1 and IgE switching in B cells
Ningshu Liu, Noriko Ohnishi, Lin Ni, Shizuo Akira and Kevin B. Bacon
Nature Immunology 4, 687–693
(July 2003); doi:10.1038/ni941
| Abstract | Full Text (HTML/PDF) |
news and views
T-bet: The Toll-bridge to class-switch recombination?
Ian R. Rifkin and Ann Marshak-Rothstein
Nature Immunology 4, 650–652
(July 2003); doi:10.1038/ni0703-650
| Full Text (HTML/PDF) |
review article
Pathogens: raft hijackers
Santos Mañes, Gustavo del Real and Carlos Martínez-A
Nature Reviews Immunology 3, 557–568
(July 2003); doi:10.1038/nri1129
| Abstract | Full Text (HTML / PDF) |
article
Role of PlGF in the intra- and intermolecular cross talk between the VEGF receptors Flt1 and Flk1
Monica Autiero, Johannes Waltenberger, Didier Communi, Andrea Kranz, Lieve Moons, Diether Lambrechts, Jens Kroll, Stephane Plaisance, Maria De Mol, Françoise Bono, Stefanie Kliche, Guido Fellbrich, Kurt Ballmer-Hofer, Domenico Maglione, Ulrike Mayr-Beyrle, Mieke Dewerchin, Saskia Dombrowski, Danica Stanimirovic, Paul Van Hummelen, Christoph Dehio, Daniel J. Hicklin, Graziella Persico, Jean-Marc Herbert, David Communi, Masabumi Shibuya, Désiré Collen, Edward M. Conway and Peter Carmeliet
Nature Medicine 9, 936–943
(July 2003); doi:10.1038/nm884
| Abstract | Full Text (HTML/PDF) |
news and views
Rules of conduct for the cystic fibrosis anion channel
Jeffrey J. Wine
Nature Medicine 9, 827–828
(July 2003); doi:10.1038/nm0703-827
| Full Text (HTML/PDF) |
news and views
Polyglutamine neurodegeneration: minding your Ps and Qs
Henry Paulson
Nature Medicine 9, 825–826
(July 2003); doi:10.1038/nm0703-825
| Full Text (HTML/PDF) |
review article
HIV-1 pathogenesis
Mario Stevenson
Nature Medicine 9, 853–860
(July 2003); doi:10.1038/nm0703-853
| Abstract | Full Text (HTML/PDF) |
article
14-3-3 is important for neuronal migration by binding to NUDEL: a molecular explanation for Miller-Dieker syndrome
Kazuhito Toyo-oka, Aki Shionoya, Michael J. Gambello, Carlos Cardoso, Richard Leventer, Heather L. Ward, Ramses Ayala, Li-Huei Tsai, William Dobyns, David Ledbetter, Shinji Hirotsune and Anthony Wynshaw-Boris
Nature Genetics 34, 274–285
(July 2003); doi:10.1038/ng1169
| Abstract | Full Text (HTML/PDF) |
letter
Hepatocyte nuclear factor 4α controls the development of a hepatic epithelium and liver morphogenesis
Fereshteh Parviz, Christine Matullo, Wendy D. Garrison, Laura Savatski, John W. Adamson, Gang Ning, Klaus H. Kaestner, Jennifer M. Rossi, Kenneth S. Zaret and Stephen A. Duncan
Nature Genetics 34, 292–296
(July 2003); doi:10.1038/ng1175
| First Paragraph | Full Text (HTML/PDF) |
letter
Gremlin is the BMP antagonist required for maintenance of Shh and Fgf signals during limb patterning
Mustafa K. Khokha, David Hsu, Lisa J. Brunet, Marc S. Dionne and Richard M. Harland
Nature Genetics 34, 303–307
(July 2003); doi:10.1038/ng1178
| First Paragraph | Full Text (HTML/PDF) |
letter
Downregulation of FUSE-binding protein and c-myc by tRNA synthetase cofactor p38 is required for lung cell differentiation
Min Jung Kim, Bum-Joon Park, Young-Sun Kang, Hyoung June Kim, Jae-Hyun Park, Jung Woo Kang, Sang Won Lee, Jung Min Han, Han-Woong Lee and Sunghoon Kim
Nature Genetics 34, 330–336
(July 2003); doi:10.1038/ng1182
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review article
Looking back to the embryo: defining transcriptional networks in adult myogenesis
Maura H. Parker , Patrick Seale and Michael A. Rudnicki
Nature Reviews Genetics 4, 497–507
(July 2003); doi:10.1038/nrg1109
| Abstract | Full Text (HTML / PDF) |
article
Postsynaptic requirement for Abl kinases in assembly of the neuromuscular junction
Alexander J. Finn, Guoping Feng and Ann Marie Pendergast
Nature Neuroscience 6, 717–723
(July 2003); doi:10.1038/nn1071
| Abstract | Full Text (HTML/PDF) |
news and views
Agrin / MuSK signaling: willing and Abl
Steven J. Burden, Christian Fuhrer and Stevan R. Hubbard
Nature Neuroscience 6, 653–654
(July 2003); doi:10.1038/nn0703-653
| Full Text (HTML/PDF) |
review article
ThermoTRP channels and beyond: mechanisms of temperature sensation
Ardem Patapoutian , Andrea M. Peier, Gina M. Story and Veena Viswanath
Nature Reviews Neuroscience 4, 529–539
(July 2003); doi:10.1038/nrn1141
| Abstract | Full Text (HTML / PDF) |
perspectives
Timeline: The bicyclam AMD3100 story
Erik De Clercq
Nature Reviews Drug Discovery 2, 581–587
(July 2003); doi:10.1038/nrd1134
| Abstract | Full Text (HTML / PDF) |
article
Structural basis for negative regulation of hypoxia-inducible factor-1α by CITED2
Steven J. Freedman, Zhen-Yu J. Sun, Andrew L. Kung, Dennis S. France, Gerhard Wagner and Michael J. Eck
Nature Structural Biology 10, 504–512
(July 2003); doi:10.1038/nsb936
| Abstract | Full Text (HTML/PDF) |
research article
Measurement of the millisecond activation switch of G protein-coupled receptors in living cells
Jean-Pierre Vilardaga, Moritz Bünemann, Cornelius Krasel, Marián Castro and Martin J. Lohse
Nature Biotechnology 21, 807–812
(July 2003); doi:10.1038/nbt838
| Abstract | Full Text (HTML/PDF) |
news and views
ExCITED about HIF
Shoumo Bhattacharya and Peter J. Ratcliffe
Nature Structural Biology 10, 501–503
(July 2003); doi:10.1038/nsb0703-501
| Full Text (HTML/PDF) |
article
Genes that act downstream of DAF-16 to influence the lifespan of Caenorhabditis elegans
Coleen T. Murphy, Steven A. McCarroll, Cornelia I. Bargmann, Andrew Fraser, Ravi S. Kamath, Julie Ahringer, Hao Li and Cynthia Kenyon
Nature 424, 277–283
(17 July 2003); doi:10.1038/nature01789
| Abstract | Full Text (HTML / PDF) |
news and views
Ageing: Microarraying mortality
David Gems and Joshua J. McElwee
Nature 424, 259–261
(17 July 2003); doi:10.1038/424259a
| Full Text (HTML / PDF) |
letters to nature
Analgesia and hyperalgesia from GABA-mediated modulation of the cerebral cortex
Luc Jasmin, Samuel D. Rabkin, Alberto Granato, Abdennacer Boudah and Peter T. Ohara
Nature 424, 316–320
(17 July 2003); doi:10.1038/nature01808
| First Paragraph | Full Text (HTML / PDF) |
letters to nature
A cytoplasmic region determines single-channel conductance in 5-HT3 receptors
Stephen P. Kelley, James I. Dunlop, Ewen F. Kirkness, Jeremy J. Lambert and John A. Peters
Nature 424, 321–324
(17 July 2003); doi:10.1038/nature01788
| First Paragraph | Full Text (HTML / PDF) |
letters to nature
Viral infection switches non-plasmacytoid dendritic cells into high interferon producers
Sandra S. Diebold, Maria Montoya, Hermann Unger, Lena Alexopoulou, Polly Roy, Linsey E. Haswell, Aymen Al-Shamkhani, Richard Flavell, Persephone Borrow and Caetano Reis e Sousa
Nature 424, 324–328
(17 July 2003); doi:10.1038/nature01783
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letters to nature
Impairment of dendritic cells and adaptive immunity by anthrax lethal toxin
Anshu Agrawal, Jai Lingappa, Stephen H. Leppla, Sudhanshu Agrawal, Abdul Jabbar, Conrad Quinn and Bali Pulendran
Nature 424, 329–334
(17 July 2003); doi:10.1038/nature01794
| First Paragraph | Full Text (HTML / PDF) |
letters to nature
Two-piconewton slip bond between fibronectin and the cytoskeleton depends on talin
Guoying Jiang, Grégory Giannone, David R. Critchley, Emiko Fukumoto and Michael P. Sheetz
Nature 424, 334–337
(17 July 2003); doi:10.1038/nature01805
| First Paragraph | Full Text (HTML / PDF) |
letter
Inactivating E2f1 reverts apoptosis resistance and cancer sensitivity in Trp53-deficient mice
Norbert M. Wikonkal, Eva Remenyik, Dejan Knezevic, Wengeng Zhang, Ming Liu, Hongyu Zhao, T. R. Berton, David G. Johnson and Douglas E. Brash
Nature Cell Biology 5, 655–660
(July 2003); doi:10.1038/ncb1001
| First Paragraph | Full Text (HTML/PDF) |
news and views
The yin and yang of E2F-1: balancing life and death
Nicholas B. La Thangue
Nature Cell Biology 5, 587–589
(July 2003); doi:10.1038/ncb0703-587
| Full Text (HTML/PDF) |
review article
Extracellular calcium sensing and signalling
Aldebaran M. Hofer and Edward M. Brown
Nature Reviews Molecular Cell Biology 4, 530–538
(July 2003); doi:10.1038/nrm1154
| Summary | Full Text (HTML / PDF) |
perspectives
Innovation: Looking forward to seeing calcium
Rüdiger Rudolf, Marco Mongillo, Rosario Rizzuto and Tullio Pozzan
Nature Reviews Molecular Cell Biology 4, 579–586
(July 2003); doi:10.1038/nrm1153
| Summary | Full Text (HTML / PDF) |
article
The inhibitory function of B7 costimulators in T cell responses to foreign and self-antigens
Jens Lohr, Birgit Knoechel, Shuwei Jiang, Arlene H Sharpe and Abul K Abbas
Nature Immunology 4, 664–669
(July 2003); doi:10.1038/ni939
| Abstract | Full Text (HTML/PDF) |
article
Interleukin 7 and T cell receptor signals regulate homeostasis of CD4 memory cells
Benedict Seddon, Peter Tomlinson and Rose Zamoyska
Nature Immunology 4, 680–686
(July 2003); doi:10.1038/ni946
| Abstract | Full Text (HTML/PDF) |
review article
Three or more routes for leukocyte migration into the central nervous system
Richard M. Ransohoff, Pia Kivisäkk and Grahame Kidd
Nature Reviews Immunology 3, 569–581
(July 2003); doi:10.1038/nri1130
| Summary | Full Text (HTML / PDF) |
review article
Regulation of IL4 gene expression by T cells and therapeutic perspectives
Min Li-Weber and Peter H. Krammer
Nature Reviews Immunology 3, 534–543
(July 2003); doi:10.1038/nri1128
| Summary | Full Text (HTML / PDF) |
article
SSeCKS regulates angiogenesis and tight junction formation in blood-brain barrier
Sae-Won Lee, Woo Jean Kim, Yoon Kyung Choi, Hyun Seok Song, Myung Jin Son, Irwin H. Gelman, Yung-Jin Kim and Kyu-Won Kim
Nature Medicine 9, 900–906
(July 2003); doi:10.1038/nm889
| Abstract | Full Text (HTML/PDF) |
news and views
Building up the blood-brain barrier
Peter Rieckmann and Britta Engelhardt
Nature Medicine 9, 828–829
(July 2003); doi:10.1038/nm0703-828
| Full Text (HTML/PDF) |
news and views
Angiogenesis inhibitors: motivators of metastasis?
Patricia S Steeg
Nature Medicine 9, 822–823
(July 2003); doi:10.1038/nm0703-822
| Full Text (HTML/PDF) |
perspectives
CpG motifs: the active ingredient in bacterial extracts?
Arthur M Krieg
Nature Medicine 9, 831–835
(July 2003); doi:10.1038/nm0703-831
| Abstract | Full Text (HTML/PDF) |
article
Neurexin mediates the assembly of presynaptic terminals
Camin Dean, Francisco G Scholl, Jenny Choih, Shannon DeMaria, James Berger, Ehud Isacoff and Peter Scheiffele
Nature Neuroscience 6, 708–716
(July 2003); doi:10.1038/nn1074
| Abstract | Full Text (HTML/PDF) |
article
Opsin activation as a cause of congenital night blindness
Shengnan Jin, M Carter Cornwall and Daniel D Oprian
Nature Neuroscience 6, 731–735
(July 2003); doi:10.1038/nn1070
| Abstract | Full Text (HTML/PDF) |
review article
Half a century of neural prepatterning: the story of a few bristles and many genes
José Luis Gómez-Skarmeta, Sonsoles Campuzano and Juan Modolell
Nature Reviews Neuroscience 4, 587–598
(July 2003); doi:10.1038/nrn1142
| Summary | Full Text (HTML / PDF) |
research article
Phosphoinositide profiling in complex lipid mixtures using electrospray ionization mass spectrometry
Markus R Wenk, Louise Lucast, Gilbert Di Paolo, Anthony J Romanelli, Sharon F Suchy, Robert L Nussbaum, Gary W Cline, Gerald I Shulman, Walter McMurray and Pietro De Camilli
Nature Biotechnology 21, 813–817
(July 2003); doi:10.1038/nbt837
| First Paragraph | Full Text (HTML/PDF) |
article
Structural and functional insights into PINCH LIM4 domain-mediated integrin signaling
Algirdas Velyvis, Julia Vaynberg, Yanwu Yang, Olga Vinogradova, Yongjun Zhang, Chuanyue Wu and Jun Qin
Nature Structural Biology 10, 558–564
(July 2003); doi:10.1038/nsb938
| Abstract | Full Text (HTML/PDF) |
letters to nature
T-type calcium channel regulation by specific G-protein βγ subunits
Joshua T. Wolfe, Hongge Wang, Jason Howard, James C. Garrison and Paula Q. Barrett
Nature 424, 209–213
(10 July 2003); doi:10.1038/nature01772
| First Paragraph | Full Text (HTML / PDF) |
letters to nature
HIV-1 Nef intersects the macrophage CD40L signalling pathway to promote resting-cell infection
Simon Swingler, Beda Brichacek, Jean-Marc Jacque, Catherine Ulich, Jin Zhou and Mario Stevenson
Nature 424, 213–219
(10 July 2003); doi:10.1038/nature01749
| First Paragraph | Full Text (HTML / PDF) |
news and views
HIV: Cross-talk and viral reservoirs
Roger J. Pomerantz
Nature 424, 136–137
(10 July 2003); doi:10.1038/424136a
| Full Text (HTML / PDF) |
letters to nature
JNK phosphorylates paxillin and regulates cell migration
Cai Huang, Zenon Rajfur, Christoph Borchers, Michael D. Schaller and Ken Jacobson
Nature 424, 219–223
(10 July 2003); doi:10.1038/nature01745
| First Paragraph | Full Text (HTML / PDF) |
letters to nature
Acute mutation of retinoblastoma gene function is sufficient for cell cycle re-entry
Julien Sage, Abigail L. Miller, Pedro A. Pérez-Mancera, Julianne M. Wysocki and Tyler Jacks
Nature 424, 223–228
(10 July 2003); doi:10.1038/nature01764
| First Paragraph | Full Text (HTML / PDF) |
news and views
Tumour suppressors: Timing will tell
Anton Berns
Nature 424, 140–141
(10 July 2003); doi:10.1038/424140a
| Full Text (HTML / PDF) |
letters to nature
Xpd/Ercc2 regulates CAK activity and mitotic progression
Jian Chen, Stéphane Larochelle, Xiaoming Li and Beat Suter
Nature 424, 228–232
(10 July 2003); doi:10.1038/nature01746
| First Paragraph | Full Text (HTML / PDF) |
news and views
Cell biology: The molecules that make muscle
Donald Gullberg
Nature 424, 138–140
(10 July 2003); doi:10.1038/424138a
| Full Text (HTML / PDF) |
letter
Accumulation of anchored proteins forms membrane diffusion barriers during neuronal polarization
Chieko Nakada, Kenneth Ritchie, Yuichi Oba, Mitsuhiro Nakamura, Yoko Hotta, Ryota Iino, Rinshi S. Kasai, Kazuhiko Yamaguchi, Takahiro Fujiwara and Akihiro Kusumi
Nature Cell Biology 5, 626–632
(July 2003); doi:10.1038/ncb1009
| First Paragraph | Full Text (HTML/PDF) |
news and views
Neuronal polarization: building fences for molecular segregation
Carlos G. Dotti and Mu-ming Poo
Nature Cell Biology 5, 591–594
(July 2003); doi:10.1038/ncb0703-591b
| Full Text (HTML/PDF) |
letter
Inhibition of caspase-9 through phosphorylation at Thr 125 by ERK MAPK
Lindsey A. Allan, Nick Morrice, Suzanne Brady, Gareth Magee, Shalini Pathak and Paul R. Clarke
Nature Cell Biology 5, 647–654
(July 2003); doi:10.1038/ncb1005
| First Paragraph | Full Text (HTML/PDF) |
review article
Calcium signalling during embryonic development
Sarah E. Webb and Andrew L. Miller
Nature Reviews Molecular Cell Biology 4, 539–551
(July 2003); doi:10.1038/nrm1149
| Summary | Full Text (HTML / PDF) |
review article
Regulation of cell death: the calcium-apoptosis link
Sten Orrenius, Boris Zhivotovsky and Pierluigi Nicotera
Nature Reviews Molecular Cell Biology 4, 552–565
(July 2003); doi:10.1038/nrm1150
| Summary | Full Text (HTML / PDF) |
article
A structural basis for immunodominant human T cell receptor recognition
Guillaume B E Stewart-Jones, Andrew J McMichael, John I Bell, David I Stuart and E Yvonne Jones
Nature Immunology 4, 657–663
(July 2003); doi:10.1038/ni942
| Abstract | Full Text (HTML/PDF) |
news and views
The problem of plain vanilla peptides
Mark M Davis
Nature Immunology 4, 649–650
(July 2003); doi:10.1038/ni0703-649
| Full Text (HTML/PDF) |
review article
The immunological and genetic basis of inflammatory bowel disease
Gerd Bouma and Warren Strober
Nature Reviews Immunology 3, 521–533
(July 2003); doi:10.1038/nri1132
| Summary | Full Text (HTML / PDF) |
article
Mimicry and autoantibody-mediated neuronal cell signaling in Sydenham chorea
Christine A Kirvan, Susan E Swedo, Janet S Heuser and Madeleine W Cunningham
Nature Medicine 9, 914–920
(July 2003); doi:10.1038/nm892
| Abstract | Full Text (HTML/PDF) |
news and views
Letting antibodies get to your head
Robert S Fujinami and Thayne L Sweeten
Nature Medicine 9, 823–825
(July 2003); doi:10.1038/nm0703-823
| Full Text (HTML/PDF) |
review article
Molecular mechanisms of glioma invasiveness: the role of proteases
Jasti S. Rao
Nature Reviews Cancer 3, 489–501
(July 2003); doi:10.1038/nrc1121
| Summary | Full Text (HTML / PDF) |
article
Specification of dorsal telencephalic character by sequential Wnt and FGF signaling
Lena Gunhaga, Matthew Marklund, My Sjödal, Jen-Chih Hsieh, Thomas M Jessell and Thomas Edlund
Nature Neuroscience 6, 701–707
(July 2003); doi:10.1038/nn1068
| Abstract | Full Text (HTML/PDF) |
article
A T-type calcium channel required for normal function of a mammalian mechanoreceptor
Jung-Bum Shin, Carlos Martinez-Salgado, Paul A Heppenstall and Gary R Lewin
Nature Neuroscience 6, 724–730
(July 2003); doi:10.1038/nn1076
| Abstract | Full Text (HTML/PDF) |
review article
The motor infrastructure: from ion channels to neuronal networks
Sten Grillner
Nature Reviews Neuroscience 4, 573–586
(July 2003); doi:10.1038/nrn1137
| Summary | Full Text (HTML / PDF) |
review article
Targeting JNK for therapeutic benefit: from junk to gold?
Anthony M. Manning and Roger J. Davis
Nature Reviews Drug Discovery 2, 554–565
(July 2003); doi:10.1038/nrd1132
| Summary | Full Text (HTML / PDF) |
article
Structure of human dCK suggests strategies to improve anticancer and antiviral therapy
Elisabetta Sabini, Stephan Ort, Christian Monnerjahn, Manfred Konrad and Arnon Lavie
Nature Structural Biology 10, 513–519
(July 2003); doi:10.1038/nsb942
| Abstract | Full Text (HTML/PDF) |
article
Structure of the core domain of human cardiac troponin in the Ca2+-saturated form
Soichi Takeda, Atsuko Yamashita, Kayo Maeda and Yuichiro Maéda
Nature 424, 35–41
(03 July 2003); doi:10.1038/nature01780
| Abstract | Full Text (HTML / PDF) |
letters to nature
A TRPV family ion channel required for hearing in Drosophila
Janghwan Kim, Yun Doo Chung, Dae-young Park, SooKyung Choi, Dong Wook Shin, Heun Soh, Hye Won Lee, Wonseok Son, Jeongbin Yim, Chul-Seung Park, Maurice J. Kernan and Changsoo Kim
Nature 424, 81–84
(03 July 2003); doi:10.1038/nature01733
| First Paragraph | Full Text (HTML / PDF) |
news and views
Ion channels: Hearing aid
Rachel A. Dumont and Peter G. Gillespie
Nature 424, 28–29
(03 July 2003); doi:10.1038/424028a
| Full Text (HTML / PDF) |
letters to nature
Assessing the redundancy of MADS-box genes during carpel and ovule development
Anusak Pinyopich, Gary S. Ditta, Beth Savidge, Sarah J. Liljegren, Elvira Baumann, Ellen Wisman and Martin F. Yanofsky
Nature 424, 85–88
(03 July 2003); doi:10.1038/nature01741
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letters to nature
Selective imprinting of gut-homing T cells by Peyer's patch dendritic cells
J. Rodrigo Mora, Maria Rosa Bono, N. Manjunath, Wolfgang Weninger, Lois L. Cavanagh, Mario Rosemblatt and Ulrich H. von Andrian
Nature 424, 88–93
(03 July 2003); doi:10.1038/nature01726
| First Paragraph | Full Text (HTML / PDF) |
letter
The cell junction protein VAB-9 regulates adhesion and epidermal morphology in C. elegans
Jeffrey S. Simske, Mathias Köppen, Paul Sims, Jonathan Hodgkin, Alicia Yonkof and Jeff Hardin
Nature Cell Biology 5, 619–625
(July 2003); doi:10.1038/ncb1002
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Claudin complexities at the apical junctional complex
Ulrich Tepass
Nature Cell Biology 5, 595–597
(July 2003); doi:10.1038/ncb0703-595
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Ubp3 requires a cofactor, Bre5, to specifically de-ubiquitinate the COPII protein, Sec23
Mickaël Cohen, Françoise Stutz, Naïma Belgareh, Rosine Haguenauer-Tsapis and Catherine Dargemont
Nature Cell Biology 5, 661–667
(July 2003); doi:10.1038/ncb1003
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review article
Calcium signalling: dynamics, homeostasis and remodelling
Michael J. Berridge, Martin D. Bootman and H. Llewelyn Roderick
Nature Reviews Molecular Cell Biology 4, 517–529
(July 2003); doi:10.1038/nrm1155
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BTLA is a lymphocyte inhibitory receptor with similarities to CTLA-4 and PD-1
Norihiko Watanabe, Maya Gavrieli, John R Sedy, Jianfei Yang, Francesca Fallarino, Susan K Loftin, Michelle A Hurchla, Natalie Zimmerman, Julia Sim, Xingxing Zang, Theresa L Murphy, John H Russell, James P Allison and Kenneth M Murphy
Nature Immunology 4, 670–679
(July 2003); doi:10.1038/ni944
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More negative feedback?
Anthony J Coyle and Jose-Carlos Gutierrez-Ramos
Nature Immunology 4, 647–648
(July 2003); doi:10.1038/ni0703-647
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review article
An epigenetic view of helper T cell differentiation
K Mark Ansel, Dong U Lee and Anjana Rao
Nature Immunology 4, 616–623
(July 2003); doi:10.1038/ni0703-616
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review article
Unifying concepts in CD28, ICOS and CTLA4 co-receptor signalling
Christopher E. Rudd and Helga Schneider
Nature Reviews Immunology 3, 544–556
(July 2003); doi:10.1038/nri1131
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Deletion of cytosolic phospholipase A2 promotes striated muscle growth
Syed Haq, Heiko Kilter, Ashour Michael, Jingzang Tao, Eileen O'Leary, Xio Ming Sun, Brian Walters, Kausik Bhattacharya, Xin Chen, Lei Cui, Michele Andreucci, Anthony Rosenzweig, J. Luis Guerrero, Richard Patten, Ronglih Liao, Jeffery Molkentin, Michael Picard, Joseph V. Bonventre and Thomas Force
Nature Medicine 9, 944–951
(July 2003); doi:10.1038/nm891
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BMP-7 counteracts TGF-β1-induced epithelial-to-mesenchymal transition and reverses chronic renal injury
Michael Zeisberg, Jun-ichi Hanai, Hikaru Sugimoto, Tadanori Mammoto, David Charytan, Frank Strutz and Raghu Kalluri
Nature Medicine 9, 964–968
(July 2003); doi:10.1038/nm888
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review article
Ovarian cancer: strategies for overcoming resistance to chemotherapy
Roshan Agarwal and Stan B. Kaye
Nature Reviews Cancer 3, 502–516
(July 2003); doi:10.1038/nrc1123
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PGC-1α-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes
Vamsi K Mootha, Cecilia M Lindgren, Karl-Fredrik Eriksson, Aravind Subramanian, Smita Sihag, Joseph Lehar, Pere Puigserver, Emma Carlsson, Martin Ridderstråle, Esa Laurila, Nicholas Houstis, Mark J Daly, Nick Patterson, Jill P Mesirov, Todd R Golub, Pablo Tamayo, Bruce Spiegelman, Eric S Lander, Joel N Hirschhorn, David Altshuler and Leif C Groop
Nature Genetics 34, 267–273
(July 2003); doi:10.1038/ng1180
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PGC-1α at the crossroads of type 2 diabetes
Alan D Attie and Christina M Kendziorski
Nature Genetics 34, 244–245
(July 2003); doi:10.1038/ng0703-244
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Brain-derived neurotrophic factor regulates energy balance downstream of melanocortin-4 receptor
Baoji Xu, Evan H Goulding, Keling Zang, David Cepoi, Roger D Cone, Kevin R Jones, Laurence H Tecott and Louis F Reichardt
Nature Neuroscience 6, 736–742
(July 2003); doi:10.1038/nn1073
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The skinny on neurotrophins
Brent E Wisse and Michael W Schwartz
Nature Neuroscience 6, 655–656
(July 2003); doi:10.1038/nn0703-655
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research article
A conditionally replicating adenovirus targeted to tumor cells through activated RAS/P-MAPK-selective mRNA stabilization
Atique Ahmed, Jill Thompson, Lisa Emiliusen, Stephen Murphy, R Daniel Beauchamp, Kaori Suzuki, Ramon Alemany, Kevin Harrington and Richard G Vile
Nature Biotechnology 21, 771–777
(July 2003); doi:10.1038/nbt835
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Vectorology recapitulates virology—will it capitulate oncology?
Estaurdo Aguilar-Cordova
Nature Biotechnology 21, 756–757
(July 2003); doi:10.1038/nbt0703-756
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A molecular switch between alternative conformational states in the complex of Ran and importin β1
Reinat Nevo, Cordula Stroh, Ferry Kienberger, David Kaftan, Vlad Brumfeld, Michael Elbaum, Ziv Reich and Peter Hinterdorfer
Nature Structural Biology 10, 553–557
(July 2003); doi:10.1038/nsb940
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