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The Research Library categorizes, and provides access to, all recent signaling-related research published in the Nature Publishing Group journals. The selection is deliberately broad to facilitate access to all research impacting on the signaling community. Both primary research and review articles are included, as are 'News and Views' articles.
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letters to nature
Suppression of CED-3-independent apoptosis by mitochondrial βNAC in Caenorhabditis elegans
Tim A. Bloss, Eric S. Witze and Joel H. Rothman
Nature 424, 1066–1071
(28 August 2003); doi:10.1038/nature01920
| First Paragraph | Full Text (HTML / PDF) |
letters to nature
S-phase checkpoint proteins Tof1 and Mrc1 form a stable replication-pausing complex
Yuki Katou, Yutaka Kanoh, Masashige Bando, Hideki Noguchi, Hirokazu Tanaka, Toshihiko Ashikari, Katsunori Sugimoto and Katsuhiko Shirahige
Nature 424, 1078–1083
(28 August 2003); doi:10.1038/nature01900
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article
Cdk5 is essential for synaptic vesicle endocytosis
Timothy C. Tan, Valentina A. Valova, Chandra S. Malladi, Mark E. Graham, Leise A. Berven, Orla J. Jupp, Gurdip Hansra, Sonya J. McClure, Boris Sarcevic, Ross A. Boadle, Martin R. Larsen, Michael A. Cousin and Phillip J. Robinson
Nature Cell Biology 5, 701–710
(August 2003); doi:10.1038/ncb1020
| Abstract | Full Text (HTML/PDF) |
news and views
Cdk5 is a dynamo at the synapse
Benjamin Adam Samuels and Li-Huei Tsai
Nature Cell Biology 5, 689–690
(August 2003); doi:10.1038/ncb0803-689
| Full Text (HTML/PDF) |
news and views
The sirens' call
Valerie A. Fadok
Nature Cell Biology 5, 697–699
(August 2003); doi:10.1038/ncb0803-697
| Full Text (HTML/PDF) |
review article
A tale of two polymers: new insights into helical filaments
Edward H. Egelman
Nature Reviews Molecular Cell Biology 4, 621–631
(August 2003); doi:10.1038/nrm1176
| Abstract | Full Text (HTML / PDF) |
article
The influence of the thymic environment on the CD4-versus-CD8 T lineage decision
Matilde Canelles, Melissa L. Park, Owen M. Schwartz and B. J. Fowlkes
Nature Immunology 4, 756–764
(August 2003); doi:10.1038/ni953
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news and views
Deadbeat neighbors influence thymocyte lineage commitment
Pamela J. Fink
Nature Immunology 4, 727–728
(August 2003); doi:10.1038/ni0803-727
| Full Text (HTML/PDF) |
article
Genetically linked C-type lectin-related ligands for the NKRP1 family of natural killer cell receptors
Koho Iizuka, Olga V. Naidenko, Beatrice F. M. Plougastel, Daved H. Fremont and Wayne M. Yokoyama
Nature Immunology 4, 801–807
(August 2003); doi:10.1038/ni954
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article
BMP-2 mediates retinoid-induced apoptosis in medulloblastoma cells through a paracrine effect
Andrew R. Hallahan, Joel I. Pritchard, Roshantha A. S. Chandraratna, Richard G. Ellenbogen, J. Russel Geyer, Ryan P. Overland, Andrew D. Strand, Stephen J. Tapscott and James M. Olson
Nature Medicine 9, 1033–1038
(August 2003); doi:10.1038/nm904
| Abstract | Full Text (HTML/PDF) |
article
SOCS-3 regulates onset and maintenance of TH2-mediated allergic responses
Yoh-ichi Seki, Hiromasa Inoue, Naoko Nagata, Katsuhiko Hayashi, Satoru Fukuyama, Koichiro Matsumoto, Okiru Komine, Shinjiro Hamano, Kunisuke Himeno, Kyoko Inagaki-Ohara, Nicholas Cacalano, Anne O'Garra, Tadahilo Oshida, Hirohisa Saito, James A. Johnston, Akihiko Yoshimura and Masato Kubo
Nature Medicine 9, 1047–1054
(August 2003); doi:10.1038/nm896
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news and views
Anthrax delivers a lethal blow to host immunity
Michael N. Starnbach and R. John Collier
Nature Medicine 9, 996–997
(August 2003); doi:10.1038/nm0803-996
| Full Text (HTML/PDF) |
news and views
Sealing the leak, healing the heart
Patrick Most and Walter J. Koch
Nature Medicine 9, 993–994
(August 2003); doi:10.1038/nm0803-993
| Full Text (HTML/PDF) |
review article
Control of gut differentiation and intestinal-type gastric carcinogenesis
Yasuhito Yuasa
Nature Reviews Cancer 3, 592–600
(August 2003); doi:10.1038/nrc1141
| Abstract | Full Text (HTML / PDF) |
review article
Chemoprevention of colon cancer by calcium, vitamin D and folate: molecular mechanisms
Sergio A. Lamprecht and Martin Lipkin
Nature Reviews Cancer 3, 601–614
(August 2003); doi:10.1038/nrc1144
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article
Mutations in INVS encoding inversin cause nephronophthisis type 2, linking renal cystic disease to the function of primary cilia and left-right axis determination
Edgar A. Otto, Bernhard Schermer, Tomoko Obara, John F. O'Toole, Karl S. Hiller, Adelheid M. Mueller, Rainer G. Ruf, Julia Hoefele, Frank Beekmann, Daniel Landau, John W. Foreman, Judith A. Goodship, Tom Strachan, Andreas Kispert, Matthias T. Wolf, Marie F. Gagnadoux, Hubert Nivet, Corinne Antignac, Gerd Walz, Iain A. Drummond, Thomas Benzing and Friedhelm Hildebrandt
Nature Genetics 34, 413–420
(August 2003); doi:10.1038/ng1217
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news and views
From cilia to cyst
Terry Watnick and Gregory Germino
Nature Genetics 34, 355–356
(August 2003); doi:10.1038/ng0803-355
| Full Text (HTML/PDF) |
article
Modulation of glycine-activated ion channel function by G-protein βγ subunits
Gonzalo E. Yevenes, Robert W. Peoples, Juan C. Tapia, Jorge Parodi, Ximena Soto, Juan Olate and Luis G. Aguayo
Nature Neuroscience 6, 819–824
(August 2003); doi:10.1038/nn1095
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article
TRPC5 is a regulator of hippocampal neurite length and growth cone morphology
Anna Greka, Betsy Navarro, Elena Oancea, Anne Duggan and David E. Clapham
Nature Neuroscience 6, 837–845
(August 2003); doi:10.1038/nn1092
| Abstract | Full Text (HTML/PDF) |
review article
A clockwork web: circadian timing in brain and periphery, in health and disease
Michael H. Hastings, Akhilesh B. Reddy and Elizabeth S. Maywood
Nature Reviews Neuroscience 4, 649–661
(August 2003); doi:10.1038/nrn1177
| Abstract | Full Text (HTML / PDF) |
review article
The biochemistry of neuronal necrosis: rogue biology?
Popi Syntichaki and Nektarios Tavernarakis
Nature Reviews Neuroscience 4, 672–684
(August 2003); doi:10.1038/nrn1174
| Abstract | Full Text (HTML / PDF) |
article
Recognition of accessory protein motifs by the γ-adaptin ear domain of GGA3
Gregory J. Miller, Rafael Mattera, Juan S. Bonifacino and James H. Hurley
Nature Structural Biology 10, 599–606
(August 2003); doi:10.1038/nsb953
| Abstract | Full Text (HTML/PDF) |
article
Structural basis for binding of accessory proteins by the appendage domain of GGAs
Brett M. Collins, Gerrit J. K. Praefcke, Margaret S. Robinson and David J. Owen
Nature Structural Biology 10, 607–613
(August 2003); doi:10.1038/nsb955
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news and views
The long and short of adaptor appendages
Christine Knuehl and Frances M Brodsky
Nature Structural Biology 10, 580–582
(August 2003); doi:10.1038/nsb0803-580
| Full Text (HTML/PDF) |
Scientific Report
RAL GTPases are linchpin modulators of human tumour-cell proliferation and survival
Yuchen Chien & Michael A. White
EMBO reports 4, 800–806
(August 2003); doi:10.1038/sj.embor.embor899
| Full Text (HTML/PDF) |
letters to nature
Different domains of synaptotagmin control the choice between kiss-and-run and full fusion
Chih-Tien Wang, Juu-Chin Lu, Jihong Bai, Payne Y. Chang, Thomas F. J. Martin, Edwin R. Chapman and Meyer B. Jackson
Nature 424, 943–947
(21 August 2003); doi:10.1038/nature01857
| First Paragraph | Full Text (HTML / PDF) |
letters to nature
BAD and glucokinase reside in a mitochondrial complex that integrates glycolysis and apoptosis
Nika N. Danial, Colette F. Gramm, Luca Scorrano, Chen-Yu Zhang, Stefan Krauss, Ann M. Ranger, Sandeep Robert Datta, Michael E. Greenberg, Lawrence J. Licklider, Bradford B. Lowell, Steven P. Gygi and Stanley J. Korsmeyer
Nature 424, 952–956
(21 August 2003); doi:10.1038/nature01825
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news and views
Cell biology: Metabolism meets death
Julian Downward
Nature 424, 896–897
(21 August 2003); doi:10.1038/424896a
| Full Text (HTML / PDF) |
letters to nature
Feedback regulation of MAPK signalling by an RNA-binding protein
Reiko Sugiura, Ayako Kita, Yasuhito Shimizu, Hisato Shuntoh, Susie O. Sio and Takayoshi Kuno
Nature 424, 961–965
(21 August 2003); doi:10.1038/nature01907
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letters to nature
Complex between nidogen and laminin fragments reveals a paradigmatic β-propeller interface
Junichi Takagi , Yuting Yang , Jin-huan Liu, Jia-huai Wang and Timothy A. Springer
Nature 424, 969–974
(21 August 2003); doi:10.1038/nature01873
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news and views
Cell biology: Tumour jailbreak
Kenneth M. Yamada
Nature 424, 889–890
(21 August 2003); doi:10.1038/424889a
| Full Text (HTML / PDF) |
review article
The role of stomata in sensing and driving environmental change
Alistair M. Hetherington and F. Ian Woodward
Nature 424, 901–908
(21 August 2003); doi:10.1038/nature01843
| Abstract | Full Text (HTML / PDF) |
letter
Cdc42-dependent actin polymerization during compensatory endocytosis in Xenopus eggs
Anna Marie Sokac, Carl Co, Jack Taunton and William Bement
Nature Cell Biology 5, 727–732
(August 2003); doi:10.1038/ncb1025
| First Paragraph | Full Text (HTML/PDF) |
news and views
Actin puts on the squeeze
Dorothy A. Schafer
Nature Cell Biology 5, 693–694
(August 2003); doi:10.1038/ncb0803-693
| Full Text (HTML/PDF) |
perspectives
Diverse cellular and molecular mechanisms contribute to epithelial plasticity and metastasis
Stefan Grünert, Martin Jechlinger and Hartmut Beug
Nature Reviews Molecular Cell Biology 4, 657–665
(August 2003); doi:10.1038/nrm1175
| Abstract | Full Text (HTML / PDF) |
article
Contribution of BCAP to maintenance of mature B cells through c-Rel
Tetsuo Yamazaki and Tomohiro Kurosaki
Nature Immunology 4, 780–786
(August 2003); doi:10.1038/ni949
| Abstract | Full Text (HTML/PDF) |
article
Thymic stromal-derived lymphopoietin distinguishes fetal from adult B cell development
Christian A. J. Voßhenrich, Ana Cumano, Werner Müller, James P. Di Santo and Paulo Vieira
Nature Immunology 4, 773–779
(August 2003); doi:10.1038/ni956
| Abstract | Full Text (HTML/PDF) |
article
Crystal structure of peptidoglycan recognition protein LB from Drosophila melanogaster
Min-Sung Kim, Minji Byun and Byung-Ha Oh
Nature Immunology 4, 787–793
(August 2003); doi:10.1038/ni952
| Abstract | Full Text (HTML/PDF) |
letter
Attenuation of seizures and neuronal death by adeno-associated virus vector galanin expression and secretion
Rebecca P. Haberman, R. Jude Samulski and Thomas J. McCown
Nature Medicine 9, 1076–1080
(August 2003); doi:10.1038/nm901
| First Paragraph | Full Text (HTML/PDF) |
news and views
Seizing hold of seizures
Gregory L. Holmes and Yezekiel Ben-Ari
Nature Medicine 9, 994–996
(August 2003); doi:10.1038/nm0803-994
| Full Text (HTML/PDF) |
review article
Caveolae: mining little caves for new cancer targets
Lucy A. Carver and Jan E. Schnitzer
Nature Reviews Cancer 3, 571–581
(August 2003); doi:10.1038/nrc1146
| Abstract | Full Text (HTML / PDF) |
article
VEGF is a modifier of amyotrophic lateral sclerosis in mice and humans and protects motoneurons against ischemic death
Diether Lambrechts, Erik Storkebaum, Masafumi Morimoto, Jurgen Del-Favero, Frederik Desmet, Stefan L. Marklund, Sabine Wyns, Vincent Thijs, Jörgen Andersson, Ingrid van Marion, Ammar Al-Chalabi, Stephanie Bornes, Rhiannon Musson, Valerie Hansen, Lars Beckman, Rolf Adolfsson, Hardev Singh Pall, Hervé Prats, Severine Vermeire, Paul Rutgeerts, Shigehiro Katayama, Takuya Awata, Nigel Leigh, Loïc Lang-Lazdunski, Mieke Dewerchin, Christopher Shaw, Lieve Moons, Robert Vlietinck, Karen E. Morrison, Wim Robberecht, Christine Van Broeckhoven, Désiré Collen, Peter M. Andersen and Peter Carmeliet
Nature Genetics 34, 383–394
(August 2003); doi:10.1038/ng1211
| Abstract | Full Text (HTML/PDF) |
news and views
A new piece of the ALS puzzle
John L. Cleveland
Nature Genetics 34, 357–358
(August 2003); doi:10.1038/ng0803-357
| Full Text (HTML/PDF) |
article
Localization of PIP2 activation gate in inward rectifier K+ channels
Jun Xiao, Xiao-guang Zhen and Jian Yang
Nature Neuroscience 6, 811–818
(August 2003); doi:10.1038/nn1090
| Abstract | Full Text (HTML/PDF) |
review article
PEDF: a multifaceted neurotrophic factor
Joyce Tombran-Tink and Colin J. Barnstable
Nature Reviews Neuroscience 4, 628–636
(August 2003); doi:10.1038/nrn1176
| Abstract | Full Text (HTML / PDF) |
research article
Metabolic labeling of C. elegans and D. melanogaster for quantitative proteomics
Jeroen Krijgsveld, René F Ketting, Tokameh Mahmoudi, Janik Johansen, Marta Artal-Sanz, C. Peter Verrijzer, Ronald H. A. Plasterk and Albert J. R. Heck
Nature Biotechnology 21, 927–931
(August 2003); doi:10.1038/nbt848
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article
A conserved amphipathic helix in WASP/Scar proteins is essential for activation of Arp2/3 complex
Sanjay C. Panchal, Donald A. Kaiser, Eduardo Torres, Thomas D. Pollard and Michael K. Rosen
Nature Structural Biology 10, 591–598
(August 2003); doi:10.1038/nsb952
| Abstract | Full Text (HTML/PDF) |
news and views
Now, swing your partner! 3D-domain switching of WASP activates Arp2/3 complex
Sarah E. Hitchcock-DeGregori
Nature Structural Biology 10, 583–584
(August 2003); doi:10.1038/nsb0803-583
| Full Text (HTML/PDF) |
article
Identification of Lps2 as a key transducer of MyD88-independent TIR signalling
K. Hoebe, X. Du, P. Georgel, E. Janssen, K. Tabeta, S. O. Kim, J. Goode, P. Lin, N. Mann, S. Mudd, K. Crozat, S. Sovath, J. Han and B. Beutler
Nature 424, 743–748
(14 August 2003); doi:10.1038/nature01889
| Abstract | Full Text (HTML / PDF) |
news and views
Immunology: Another toll road
Wen-Chen Yeh and Nien-Jung Chen
Nature 424, 736–737
(14 August 2003); doi:10.1038/424736a
| Full Text (HTML / PDF) |
letters to nature
Direct modulation of synaptic vesicle priming by GABAB receptor activation at a glutamatergic synapse
Takeshi Sakaba and Erwin Neher
Nature 424, 775–778
(14 August 2003); doi:10.1038/nature01859
| First Paragraph | Full Text (HTML / PDF) |
letters to nature
P2X4 receptors induced in spinal microglia gate tactile allodynia after nerve injury
Makoto Tsuda, Yukari Shigemoto-Mogami, Schuichi Koizumi, Akito Mizokoshi, Shinichi Kohsaka, Michael W. Salter and Kazuhide Inoue
Nature 424, 778–783
(14 August 2003); doi:10.1038/nature01786
| First Paragraph | Full Text (HTML / PDF) |
news and views
Neurobiology: New player in pain
Edwin W. McCleskey
Nature 424, 729–730
(14 August 2003); doi:10.1038/424729a
| Full Text (HTML / PDF) |
letters to nature
CYLD is a deubiquitinating enzyme that negatively regulates NF-κB activation by TNFR family members
Eirini Trompouki, Eudoxia Hatzivassiliou, Theodore Tsichritzis, Hannah Farmer, Alan Ashworth and George Mosialos
Nature 424, 793–796
(14 August 2003); doi:10.1038/nature01803
| First Paragraph | Full Text (HTML / PDF) |
letters to nature
Loss of the cylindromatosis tumour suppressor inhibits apoptosis by activating NF-κB
Thijn R. Brummelkamp, Sebastian M. B. Nijman, Annette M. G. Dirac and René Bernards
Nature 424, 797–801
(14 August 2003); doi:10.1038/nature01811
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letters to nature
The tumour suppressor CYLD negatively regulates NF-κB signalling by deubiquitination
Andrew Kovalenko Christine Chable-Bessia, Giuseppina Cantarella, Alain Israël, David Wallach & Gilles Courtois
Nature 424, 801–805
(14 August 2003); doi:10.1038/nature01802
| First Paragraph | Full Text (HTML / PDF) |
news and views
Signal transduction: Aspirin, ubiquitin and cancer
Keith D. Wilkinson
Nature 424, 738–739
(14 August 2003); doi:10.1038/424738a
| Full Text (HTML / PDF) |
brief communication
Cell signalling (communication arising): Cell survival and a Gadd45-factor deficiency
Arshad Amanullah, Naiyer Azam, Arthur Balliet, Christine Hollander, Barbara Hoffman, Albert Fornace Jr and Dan Liebermann
Nature 424, 741
(14 August 2003); doi:10.1038/424741b
| First Paragraph | Full Text (HTML / PDF) |
letter
Integrins and EGFR coordinately regulate the pro-apoptotic protein Bim to prevent anoikis
Mauricio J. Reginato, Kenna R. Mills, Jessica K. Paulus, Danielle K. Lynch, Dennis C. Sgroi, Jayanta Debnath, Senthil K. Muthuswamy and Joan S. Brugge
Nature Cell Biology 5, 733–740
(August 2003); doi:10.1038/ncb1026
| First Paragraph | Full Text (HTML/PDF) |
news and views
Getting a GPR on spindle asymmetry
S. Swaminathan
Nature Cell Biology 5, 692
(August 2003); doi:10.1038/ncb0803-692
| Full Text (HTML/PDF) |
letter
Connexin-dependent inter-cellular communication increases invasion and dissemination of Shigella in epithelial cells
Guy Tran Van Nhieu, Caroline Clair, Roberto Bruzzone, Marc Mesnil, Philippe Sansonetti and Laurent Combettes
Nature Cell Biology 5, 720–726
(August 2003); doi:10.1038/ncb1021
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article
RAPL, a Rap1-binding molecule that mediates Rap1-induced adhesion through spatial regulation of LFA-1
Koko Katagiri, Akito Maeda, Mika Shimonaka and Tatsuo Kinashi
Nature Immunology 4, 741–748
(August 2003); doi:10.1038/ni950
| Abstract | Full Text (HTML/PDF) |
news and views
Rap1 redux
Robert T Abraham
Nature Immunology 4, 725–727
(August 2003); doi:10.1038/ni0803-725
| Full Text (HTML/PDF) |
review article
Co-stimulatory members of the TNFR family: keys to effective T-cell immunity?
Michael Croft
Nature Reviews Immunology 3, 609–620
(August 2003); doi:10.1038/nri1148
| Abstract | Full Text (HTML / PDF) |
article
Dexamethasone induction of hypertension and diabetes is PPAR-α dependent in LDL receptor-null mice
Carlos Bernal-Mizrachi, Sherry Weng, Chu Feng, Brian N. Finck, Russell H. Knutsen, Teresa C. Leone, Trey Coleman, Robert P. Mecham, Daniel P. Kelly and Clay F. Semenkovich
Nature Medicine 9, 1069–1075
(August 2003); doi:10.1038/nm898
| Abstract | Full Text (HTML/PDF) |
review article
The emerging role of lysophosphatidic acid in cancer
Gordon B. Mills and Wouter H. Moolenaar
Nature Reviews Cancer 3, 582–591
(August 2003); doi:10.1038/nrc1143
| Abstract | Full Text (HTML / PDF) |
article
Defects in whirlin, a PDZ domain molecule involved in stereocilia elongation, cause deafness in the whirler mouse and families with DFNB31
Philomena Mburu, Mirna Mustapha, Anabel Varela, Dominique Weil, Aziz El-Amraoui, Ralph H. Holme, Andreas Rump, Rachel E. Hardisty, Stéphane Blanchard, Roney S. Coimbra, Isabelle Perfettini, Nick Parkinson, Ann-Marie Mallon, Pete Glenister, Mike J. Rogers, Adam J. Paige, Lee Moir, Jo Clay, Andre Rosenthal, Xue Zhong Liu, Gonzalo Blanco, Karen P. Steel, Christine Petit and Steve D. M. Brown
Nature Genetics 34, 421–428
(August 2003); doi:10.1038/ng1208
| Abstract | Full Text (HTML/PDF) |
article
Structural basis for partial agonist action at ionotropic glutamate receptors
Rongsheng Jin, Tue G. Banke, Mark L. Mayer, Stephen F. Traynelis and Eric Gouaux
Nature Neuroscience 6, 803–810
(August 2003); doi:10.1038/nn1091
| Abstract | Full Text (HTML/PDF) |
news and views
Crystallizing our understanding of partial agonists
David S. Weiss and Yongchang Chang
Nature Neuroscience 6, 788–789
(August 2003); doi:10.1038/nn0803-788
| Full Text (HTML/PDF) |
research article
Dendritic cells, engineered to secrete a T-cell receptor mimic peptide, induce antigen-specific immunosuppression in vivo
Karsten Mahnke, Yingjie Qian, Jürgen Knop and Alexander H. Enk
Nature Biotechnology 21, 903–908
(August 2003); doi:10.1038/nbt842
| Abstract | Full Text (HTML/PDF) |
news and views
Pulling the calcium trigger
Brian D. Sykes
Nature Structural Biology 10, 588–589
(August 2003); doi:10.1038/nsb0803-588
| Full Text (HTML/PDF) |
letters to nature
Induction of dendritic spines by an extracellular domain of AMPA receptor subunit GluR2
Maria Passafaro, Terunaga Nakagawa, Carlo Sala and Morgan Sheng
Nature 424, 677–681
(07 August 2003); doi:10.1038/nature01781
| First Paragraph | Full Text (HTML / PDF) |
news and views
Neurobiology: A thorny issue
Peter H. Seeburg and Pavel Osten
Nature 424, 627–628
(07 August 2003); doi:10.1038/424627a
| Full Text (HTML / PDF) |
letters to nature
Phospholipase Cγ activates Ras on the Golgi apparatus by means of RasGRP1
Trever G. Bivona, Ignacio Pérez de Castro, Ian M. Ahearn, Theresa M. Grana, Vi K. Chiu, Peter J. Lockyer, Peter J. Cullen, Angel Pellicer, Adrienne D. Cox and Mark R. Philips
Nature 424, 694–698
(07 August 2003); doi:10.1038/nature01806
| First Paragraph | Full Text (HTML / PDF) |
news and views
Signal transduction: Life on Mars, cellularly speaking
Pier Paolo Di Fiore
Nature 424, 624–625
(07 August 2003); doi:10.1038/424624a
| Full Text (HTML / PDF) |
letters to nature
Exclusion of germ plasm proteins from somatic lineages by cullin-dependent degradation
Cynthia DeRenzo, Kimberly J. Reese and Geraldine Seydoux
Nature 424, 685–689
(07 August 2003); doi:10.1038/nature01887
| First Paragraph | Full Text (HTML / PDF) |
letters to nature
RanGTP mediates nuclear pore complex assembly
Tobias C. Walther, Peter Askjaer, Marc Gentzel, Anja Habermann, Gareth Griffiths, Matthias Wilm, Iain W. Mattaj and Martin Hetzer
Nature 424, 689–694
(07 August 2003); doi:10.1038/nature01898
| First Paragraph | Full Text (HTML / PDF) |
letter
Phosphorylation of Cdc20 is required for its inhibition by the spindle checkpoint
Eunah Chung and Rey-Huei Chen
Nature Cell Biology 5, 748–753
(August 2003); doi:10.1038/ncb1022
| First Paragraph | Full Text (HTML/PDF) |
news and views
Talin forges the links between integrins and actin
David A. Calderwood and Mark H. Ginsberg
Nature Cell Biology 5, 694–697
(August 2003); doi:10.1038/ncb0803-694
| Full Text (HTML/PDF) |
review article
The SREBP pathway — insights from Insigs and insects
Robert B. Rawson
Nature Reviews Molecular Cell Biology 4, 631–640
(August 2003); doi:10.1038/nrm1174
| Summary | Full Text (HTML / PDF) |
article
Binding of the Drosophila cytokine Spätzle to Toll is direct and establishes signaling
Alexander N R Weber, Servane Tauszig-Delamasure, Jules A Hoffmann, Eric Lelièvre, Hugues Gascan, Keith P Ray, Mary A Morse, Jean-Luc Imler and Nicholas J Gay
Nature Immunology 4, 794–800
(August 2003); doi:10.1038/ni955
| Abstract | Full Text (HTML/PDF) |
news and views
Toll gets tied in a knot
David Underhill
Nature Immunology 4, 723–724
(August 2003); doi:10.1038/ni0803-723
| Full Text (HTML/PDF) |
review article
Class II cytokine receptors and their ligands: Key antiviral and inflammatory modulators
Jean-Christophe Renauld
Nature Reviews Immunology 3, 667–676
(August 2003); doi:10.1038/nri1153
| Summary | Full Text (HTML / PDF) |
article
Endothelin-B receptor activation triggers an endogenous analgesic cascade at sites of peripheral injury
Alla Khodorova, Betsy Navarro, Laurence Sophie Jouaville, Jo-Ellen Murphy, Frank L Rice, Joseph E Mazurkiewicz, Denise Long-Woodward, Markus Stoffel, Gary R Strichartz, Rus Yukhananov and Gudarz Davar
Nature Medicine 9, 1055–1061
(August 2003); doi:10.1038/nm885
| Abstract | Full Text (HTML/PDF) |
review article
Attacking pain at its source: new perspectives on opioids
Christoph Stein, Michael Schäfer and Halina Machelska
Nature Medicine 9, 1003–1008
(August 2003); doi:10.1038/nm908
| Abstract | Full Text (HTML/PDF) |
article
Uncoupling protein-2 prevents neuronal death and diminishes brain dysfunction after stroke and brain trauma
Gustav Mattiasson, Mehrdad Shamloo, Gunilla Gido, Kavitha Mathi, Gregor Tomasevic, Saili Yi, Craig H. Warden, Roger F. Castilho, Thorsten Melcher, Mirella Gonzalez-Zulueta, Karoly Nikolich and Tadeusz Wieloch
Nature Medicine 9, 1062–1068
(August 2003); doi:10.1038/nm903
| Abstract | Full Text (HTML/PDF) |
news and views
Aurora and the hunt for cancer-modifying genes
William Dove
Nature Genetics 34, 353–354
(August 2003); doi:10.1038/ng0803-353
| Full Text (HTML/PDF) |
letter
Impaired function of p53R2 in Rrm2b-null mice causes severe renal failure through attenuation of dNTP pools
Takashi Kimura, Satoshi Takeda, Yoji Sagiya, Mitsukazu Gotoh, Yusuke Nakamura and Hirofumi Arakawa
Nature Genetics 34, 440–445
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Tomomi Fukuchi-Shimogori and Elizabeth A Grove
Nature Neuroscience 6, 825–831
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New role of δ2-glutamate receptors in AMPA receptor trafficking and cerebellar function
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Nature Neuroscience 6, 869–876
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Targeting of proteins to membranes through hedgehog auto-processing
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Nature Biotechnology 21, 936–940
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Opioid receptor random mutagenesis reveals a mechanism for G protein-coupled receptor activation
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Nature Structural Biology 10, 629–636
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scientific report
Fly and mammalian lipid phosphate phosphatase isoforms differ in activity both in vitro and in vivo
Camilla Burnett and Ken Howard
EMBO reports 4, 793–799
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Integration of interferon-α/β signalling to p53 responses in tumour suppression and antiviral defence
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Nature 424, 516–523
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Role of the prolyl isomerase Pin1 in protecting against age-dependent neurodegeneration
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Nature 424, 556–561
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Essential role for the peroxiredoxin Prdx1 in erythrocyte antioxidant defence and tumour suppression
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Nature 424, 561–565
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Machinery for protein sorting and assembly in the mitochondrial outer membrane
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Cell biology: Moving inside membranes
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Nature 424, 505–506
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letters to nature
Dimers of the N-terminal domain of phytochrome B are functional in the nucleus
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Nature 424, 571–574
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Processivity of the single-headed kinesin KIF1A through biased binding to tubulin
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Developmental biology: How to turn inside out
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Neurobiology: Motor proteins branch out
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Differing modes of tumour cell invasion have distinct requirements for Rho/ROCK signalling and extracellular proteolysis
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Nature Cell Biology 5, 711–719
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New dimensions in cell migration
Donna J. Webb and Alan F. Horwitz
Nature Cell Biology 5, 690–692
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Opinion: Transactivation joins multiple tracks to the ERK/MAPK cascade
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Nature Reviews Molecular Cell Biology 4, 651–657
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Continuous T cell receptor signaling required for synapse maintenance and full effector potential
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Nefarious abuse
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Nature Immunology 4, 729–730
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Transcription factor Egr-1 supports FGF-dependent angiogenesis during neovascularization and tumor growth
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Nature Medicine 9, 1026–1032
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Road map to metastasis
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Nature Medicine 9, 999–1000
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The genetics of malignant melanoma: lessons from mouse and man
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Nature Genetics 34, 403–412
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Calcium regulates exocytosis at the level of single vesicles
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Nature Neuroscience 6, 846–853
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A transgenic mouse model of the ubiquitin/proteasome system
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Nature Structural Biology 10, 622–628
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