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The Research Library categorizes, and provides access to, all recent signaling-related research published in the Nature Publishing Group journals. The selection is deliberately broad to facilitate access to all research impacting on the signaling community. Both primary research and review articles are included, as are 'News and Views' articles.
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letters to nature
Cytosolic pH regulates root water transport during anoxic stress through gating of aquaporins
Colette Tournaire-Roux, Moira Sutka, Hélène Javot, Elisabeth Gout, Patricia Gerbeau, Doan-Trung Luu, Richard Bligny and Christophe Maurel
Nature 425, 393–397
(25 September 2003); doi:10.1038/nature01853
| First Paragraph | Full Text (HTML / PDF) |
news and views
Plant biology: Water gate
N. Michele Holbrook and Maciej A. Zwieniecki
Nature 425, 361
(25 September 2003); doi:10.1038/425361a
| Full Text (HTML / PDF) |
letters to nature
ER-phagosome fusion defines an MHC class I cross-presentation compartment in dendritic cells
Pierre Guermonprez, Loredana Saveanu, Monique Kleijmeer, Jean Davoust, Peter van Endert and Sebastian Amigorena
Nature 425, 397–402
(25 September 2003); doi:10.1038/nature01911
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letters to nature
Phagosomes are competent organelles for antigen cross-presentation
Mathieu Houde, Sylvie Bertholet, Etienne Gagnon, Sylvain Brunet, Guillaume Goyette, Annie Laplante, Michael F. Princiotta, Pierre Thibault, David Sacks and Michel Desjardins
Nature 425, 402–406
(25 September 2003); doi:10.1038/nature01912
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news and views
Immunology: Professional secrets
Craig R. Roy
Nature 425, 351–352
(25 September 2003); doi:10.1038/425351a
| Full Text (HTML / PDF) |
letters to nature
A high-affinity conformation of Hsp90 confers tumour selectivity on Hsp90 inhibitors
Adeela Kamal, Lia Thao, John Sensintaffar, Lin Zhang, Marcus F. Boehm, Lawrence C. Fritz and Francis J. Burrows
Nature 425, 407–410
(25 September 2003); doi:10.1038/nature01913
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news and views
Cancer: The rules of attraction
Len Neckers and Yong-Sok Lee
Nature 425, 357–359
(25 September 2003); doi:10.1038/425357a
| Full Text (HTML / PDF) |
letters to nature
A structural state of the myosin V motor without bound nucleotide
Pierre-Damien Coureux, Amber L. Wells, Julie Ménétrey, Christopher M. Yengo, Carl A. Morris, H. Lee Sweeney and Anne Houdusse
Nature 425, 419–423
(25 September 2003); doi:10.1038/nature01927
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letters to nature
Electron cryo-microscopy shows how strong binding of myosin to actin releases nucleotide
Kenneth C. Holmes, Isabel Angert, F. Jon Kull, Werner Jahn and Rasmus R. Schröder
Nature 425, 423–427
(25 September 2003); doi:10.1038/nature02005
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news and views
Stem cells: To be and not to be
Haifan Lin
Nature 425, 353–355
(25 September 2003); doi:10.1038/425353a
| Full Text (HTML / PDF) |
article
Selected lipids activate phagosome actin assembly and maturation resulting in killing of pathogenic mycobacteria
Elsa Anes, Mark Philipp Kühnel, Evelyne Bos, Jose Moniz-Pereira, Anja Habermann and Gareth Griffiths
Nature Cell Biology 5, 793–802
(September 2003); doi:10.1038/ncb1036
| Abstract | Full Text (HTML/PDF) |
news and views
Phagosomes, fatty acids and tuberculosis
David G. Russell
Nature Cell Biology 5, 776–778
(September 2003); doi:10.1038/ncb0903-776
| Full Text (HTML/PDF) |
letter
Targeted movement of cell end factors in fission yeast
Heidi Browning, David D. Hackney and Paul Nurse
Nature Cell Biology 5, 812–818
(September 2003); doi:10.1038/ncb1034
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news and views
Tip of the POP2
D. Mcdonald
Nature Cell Biology 5, 778
(September 2003); doi:10.1038/ncb0903-778
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review article
Nuclear and unclear functions of SUMO
Jacob-S. Seeler and Anne Dejean
Nature Reviews Molecular Cell Biology 4, 690–699
(September 2003); doi:10.1038/nrm1200
| Abstract | Full Text (HTML / PDF) |
review article
Trefoil factors: initiators of mucosal healing
Douglas Taupin and Daniel K. Podolsky
Nature Reviews Molecular Cell Biology 4, 721–732
(September 2003); doi:10.1038/nrm1203
| Abstract | Full Text (HTML / PDF) |
perspectives
Epac: a new cAMP target and new avenues in cAMP research
Johannes L. Bos
Nature Reviews Molecular Cell Biology 4, 733–738
(September 2003); doi:10.1038/nrm1197
| Abstract | Full Text (HTML / PDF) |
article
SIGIRR, a negative regulator of Toll-like receptor-interleukin 1 receptor signaling
David Wald, Jinzhong Qin, Zhendong Zhao, Youcun Qian, Mayumi Naramura, Liping Tian, Jennifer Towne, John E. Sims, George R. Stark and Xiaoxia Li
Nature Immunology 4, 920–927
(September 2003); doi:10.1038/ni968
| Abstract | Full Text (HTML/PDF) |
news and views
SIGIRR puts the brakes on Toll-like receptors
Luke A. J. O'Neill
Nature Immunology 4, 823–824
(September 2003); doi:10.1038/ni0903-823
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article
Defective development and function of Bcl10-deficient follicular, marginal zone and B1 B cells
Liquan Xue, Stephan W Morris, Carlos Orihuela, Elaine Tuomanen, Xiaoli Cui, Renren Wen and Demin Wang
Nature Immunology 4, 857–865
(September 2003); doi:10.1038/ni963
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review article
Similarities and differences in CD4+ and CD8+ effector and memory T cell generation
Robert A. Seder and Rafi Ahmed
Nature Immunology 4, 835–842
(September 2003); doi:10.1038/ni969
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review article
The regulation of immunoglobulin E class-switch recombination
Raif S. Geha, Haifa H. Jabara and Scott R. Brodeur
Nature Reviews Immunology 3, 721–732
(September 2003); doi:10.1038/nri1181
| Abstract | Full Text (HTML / PDF) |
article
A peptide inhibitor of c-Jun N-terminal kinase protects against excitotoxicity and cerebral ischemia
Tiziana Borsello, Peter G. H. Clarke, Lorenz Hirt, Alessandro Vercelli, Mariaelena Repici, Daniel F. Schorderet, Julien Bogousslavsky and Christophe Bonny
Nature Medicine 9, 1180–1186
(September 2003); doi:10.1038/nm911
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article
Interaction between leukemic-cell VLA-4 and stromal fibronectin is a decisive factor for minimal residual disease of acute myelogenous leukemia
Takuya Matsunaga, Naofumi Takemoto, Tsutomu Sato, Rishu Takimoto, Ikuta Tanaka, Akihito Fujimi, Takehide Akiyama, Hiroyuki Kuroda, Yutaka Kawano, Masayoshi Kobune, Junji Kato, Yasuo Hirayama, Sumio Sakamaki, Kyuhei Kohda, Kensuke Miyake and Yoshiro Niitsu
Nature Medicine 9, 1158–1165
(September 2003); doi:10.1038/nm909
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article
Salusins: newly identified bioactive peptides with hemodynamic and mitogenic activities
Masayoshi Shichiri, Shinya Ishimaru, Toshio Ota, Tetsuo Nishikawa, Takao Isogai and Yukio Hirata
Nature Medicine 9, 1166–1172
(September 2003); doi:10.1038/nm913
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news and views
Escherichia coli gets the message
Klaus Winzer and Paul Williams
Nature Medicine 9, 1118–1119
(September 2003); doi:10.1038/nm0903-1118
| Full Text (HTML/PDF) |
article
Cidea-deficient mice have lean phenotype and are resistant to obesity
Zhihong Zhou, Shen Yon Toh, Zhengming Chen, Ke Guo, Chee Peng Ng, Sathivel Ponniah, Sheng-Cai Lin, Wanjin Hong and Peng Li
Nature Genetics 35, 49–56
(September 2003); doi:10.1038/ng1225
| Abstract | Full Text (HTML/PDF) |
letter
Huntingtin interacts with REST/NRSF to modulate the transcription of NRSE-controlled neuronal genes
Chiara Zuccato, Marzia Tartari, Andrea Crotti, Donato Goffredo, Marta Valenza, Luciano Conti, Tiziana Cataudella, Blair R. Leavitt, Michael R Hayden, Tõnis Timmusk, Dorotea Rigamonti and Elena Cattaneo
Nature Genetics 35, 76–83
(September 2003); doi:10.1038/ng1219
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news and views
An expanded role for wild-type huntingtin in neuronal transcription
Leslie Michels Thompson
Nature Genetics 35, 13–14
(September 2003); doi:10.1038/ng0903-13
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article
Alternative splicing of lola generates 19 transcription factors controlling axon guidance in Drosophila
Scott Goeke, Elizabeth A. Greene, Paul K. Grant, Michael A. Gates, Daniel Crowner, Toshiro Aigaki and Edward Giniger
Nature Neuroscience 6, 917–924
(September 2003); doi:10.1038/nn1105
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review article
Myelin-associated inhibitors of axonal regeneration in the adult mammalian CNS
Marie T. Filbin
Nature Reviews Neuroscience 4, 703–713
(September 2003); doi:10.1038/nrn1195
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research article
The application of bone morphogenetic proteins to dental tissue engineering
Misako Nakashima and A. Hari Reddi
Nature Biotechnology 21, 1025–1032
(September 2003); doi:10.1038/nbt864
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review article
Therapeutic antagonists and conformational regulation of integrin function
Motomu Shimaoka and Timothy A. Springer
Nature Reviews Drug Discovery 2, 703–716
(September 2003); doi:10.1038/nrd1174
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review article
p38 MAP kinases: key signalling molecules as therapeutic targets for inflammatory diseases
Sanjay Kumar, Jeffrey Boehm and John C. Lee
Nature Reviews Drug Discovery 2, 717–726
(September 2003); doi:10.1038/nrd1177
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review article
Anti-TNF-α therapies: the next generation
Michael A. Palladino, Frances Rena Bahjat, Emmanuel A. Theodorakis and Lyle L. Moldawer
Nature Reviews Drug Discovery 2, 736–746
(September 2003); doi:10.1038/nrd1175
| Abstract | Full Text (HTML / PDF) |
letters to nature
Chemokine receptor CXCR4 downregulated by von Hippel-Lindau tumour suppressor pVHL
Peter Staller, Jitka Sulitkova, Joanna Lisztwan, Holger Moch, Edward J. Oakeley and Wilhelm Krek
Nature 425, 307–311
(18 September 2003); doi:10.1038/nature01874
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news and views
Cancer: Cues for migration
René Bernards
Nature 425, 247–248
(18 September 2003); doi:10.1038/425247a
| Full Text (HTML / PDF) |
letters to nature
The BTB protein MEL-26 is a substrate-specific adaptor of the CUL-3 ubiquitin-ligase
Lionel Pintard, John H. Willis, Andrew Willems, Jacque-Lynne F. Johnson, Martin Srayko, Thimo Kurz, Sarah Glaser, Paul E. Mains, Mike Tyers, Bruce Bowerman and Matthias Peter
Nature 425, 311–316
(18 September 2003); doi:10.1038/nature01959
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letters to nature
BTB proteins are substrate-specific adaptors in an SCF-like modular ubiquitin ligase containing CUL-3
Lai Xu, Yue Wei, Jerome Reboul, Philippe Vaglio, Tae-Ho Shin, Marc Vidal, Stephen J. Elledge and J. Wade Harper
Nature 425, 316–321
(18 September 2003); doi:10.1038/nature01985
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letter
Sphingosylphosphorylcholine regulates keratin network architecture and visco-elastic properties of human cancer cells
Michael Beil, Alexandre Micoulet, Götz von Wichert, Stephan Paschke, Paul Walther, M. Bishr Omary, Paul P. Van Veldhoven, Ulrike Gern, Elke Wolff-Hieber, Juliane Eggermann, Johannes Waltenberger, Guido Adler, Joachim Spatz and Thomas Seufferlein
Nature Cell Biology 5, 803–811
(September 2003); doi:10.1038/ncb1037
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letter
CRMP-2 regulates polarized Numb-mediated endocytosis for axon growth
Takashi Nishimura, Yuko Fukata, Katsuhiro Kato, Tomoya Yamaguchi, Yoshiharu Matsuura, Hiroyuki Kamiguchi and Kozo Kaibuchi
Nature Cell Biology 5, 819–826
(September 2003); doi:10.1038/ncb1039
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review article
Titin: properties and family relationships
Larissa Tskhovrebova and John Trinick
Nature Reviews Molecular Cell Biology 4, 679–689
(September 2003); doi:10.1038/nrm1198
| Abstract | Full Text (HTML / PDF) |
review article
Phosphatases in cell-matrix adhesion and migration
Melinda Larsen, Michel L. Tremblay and Kenneth M. Yamada
Nature Reviews Molecular Cell Biology 4, 700–711
(September 2003); doi:10.1038/nrm1199
| Abstract | Full Text (HTML / PDF) |
article
The threshold pattern of calcineurin-dependent gene expression is altered by loss of the endogenous inhibitor calcipressin
Sandra Ryeom, Rebecca J. Greenwald, Arlene H. Sharpe and Frank McKeon
Nature Immunology 4, 874–881
(September 2003); doi:10.1038/ni966
| Abstract | Full Text (HTML/PDF) |
news and views
Calcium-independent calcineurin regulation
Richard V. Parry and Carl H. June
Nature Immunology 4, 821–823
(September 2003); doi:10.1038/ni0903-821
| Full Text (HTML/PDF) |
article
CIITA-regulated plexin-A1 affects T-cell-dendritic cell interactions
Athena W. Wong, W. June Brickey, Debra J. Taxman, Hendrick W. van Deventer, William Reed, Jian Xin Gao, Pan Zheng, Yang Liu, Ping Li, Janice S. Blum, Karen P. McKinnon and Jenny P-Y Ting
Nature Immunology 4, 891–898
(September 2003); doi:10.1038/ni960
| Abstract | Full Text (HTML/PDF) |
news and views
ComPLEXIN new targets for CIITA
Walter Reith
Nature Immunology 4, 819–820
(September 2003); doi:10.1038/ni0903-819
| Full Text (HTML/PDF) |
perspectives
Are follicular dendritic cells really good for nothing?
Marie H. Kosco-Vilbois
Nature Reviews Immunology 3, 764–769
(September 2003); doi:10.1038/nri1179
| Abstract | Full Text (HTML / PDF) |
article
L-type Ca2+ channels provide a major pathway for iron entry into cardiomyocytes in iron-overload cardiomyopathy
Gavin Y. Oudit, Hui Sun, Maria G. Trivieri, Sheryl E. Koch, Fayez Dawood, Cameron Ackerley, Mehrdad Yazdanpanah, Greg J. Wilson, Arnold Schwartz, Peter P. Liu and Peter H. Backx
Nature Medicine 9, 1187–1194
(September 2003); doi:10.1038/nm920
| Abstract | Full Text (HTML/PDF) |
article
Cyclophilin A modulates the sensitivity of HIV-1 to host restriction factors
Greg J. Towers, Theodora Hatziioannou, Simone Cowan, Stephen P. Goff, Jeremy Luban and Paul D. Bieniasz
Nature Medicine 9, 1138–1143
(September 2003); doi:10.1038/nm910
| Abstract | Full Text (HTML/PDF) |
news and views
HIV-1 infection: fooling the gatekeeper
Bryan R. Cullen
Nature Medicine 9, 1112–1113
(September 2003); doi:10.1038/nm0903-1112
| Full Text (HTML/PDF) |
review article
Mechanisms of sarcoma development
Lee J. Helman and Paul Meltzer
Nature Reviews Cancer 3, 685–694
(September 2003); doi:10.1038/nrc1168
| Abstract | Full Text (HTML / PDF) |
article
Trans-acting regulatory variation in Saccharomyces cerevisiae and the role of transcription factors
Gaël Yvert, Rachel B. Brem, Jacqueline Whittle, Joshua M. Akey, Eric Foss, Erin N. Smith, Rachel Mackelprang and Leonid Kruglyak
Nature Genetics 35, 57–64
(September 2003); doi:10.1038/ng1222
| Abstract | Full Text (HTML/PDF) |
review article
Cancer susceptibility in the mouse: genetics, biology and implications for human cancer
Peter Demant
Nature Reviews Genetics 4, 721–734
(September 2003); doi:10.1038/nrg1157
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article
Lmx1b is essential for the development of serotonergic neurons
Yu-Qiang Ding, Ulrika Marklund, Wenlin Yuan, Jun Yin, Lauren Wegman, Johan Ericson, Evan Deneris, Randy L. Johnson and Zhou-Feng Chen
Nature Neuroscience 6, 933–938
(September 2003); doi:10.1038/nn1104
| Abstract | Full Text (HTML/PDF) |
news and views
Tag, you're degraded
Evelyn Jabri
Nature Structural Biology 10, 676
(September 2003); doi:10.1038/nsb0903-676
| Full Text (HTML/PDF) |
research article
Phosphospecific proteolysis for mapping sites of protein phosphorylation
Zachary A. Knight, Birgit Schilling, Richard H. Row, Denise M. Kenski, Bradford W. Gibson and Kevan M. Shokat
Nature Biotechnology 21, 1047–1054
(September 2003); doi:10.1038/nbt863
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letters to nature
Control of spontaneous and damage-induced mutagenesis by SUMO and ubiquitin conjugation
Philipp Stelter and Helle D. Ulrich
Nature 425, 188–191
(11 September 2003); doi:10.1038/nature01965
| First Paragraph | Full Text (HTML / PDF) |
letters to nature
Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan
Konrad T. Howitz, Kevin J. Bitterman, Haim Y. Cohen, Dudley W. Lamming, Siva Lavu, Jason G. Wood, Robert E. Zipkin, Phuong Chung, Anne Kisielewski, Li-Li Zhang, Brandy Scherer and David A. Sinclair
Nature 425, 191–196
(11 September 2003); doi:10.1038/nature01960
| First Paragraph | Full Text (HTML / PDF) |
news and views
Ageing: A toast to long life
Toren Finkel
Nature 425, 132–133
(11 September 2003); doi:10.1038/425132a
| Full Text (HTML / PDF) |
letters to nature
A cell surface receptor mediates extracellular Ca2+ sensing in guard cells
Shengcheng Han, Ruhang Tang, Lisa K. Anderson, Todd E. Woerner and Zhen-Ming Pei
Nature 425, 196–200
(11 September 2003); doi:10.1038/nature01932
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letters to nature
Structural basis for modulation and agonist specificity of HCN pacemaker channels
William N. Zagotta, Nelson B. Olivier, Kevin D. Black, Edgar C. Young, Rich Olson and Eric Gouaux
Nature 425, 200–205
(11 September 2003); doi:10.1038/nature01922
| First Paragraph | Full Text (HTML / PDF) |
news and views
Cardiovascular biology: Signalling silenced
Edward M. Conway and Peter Carmeliet
Nature 425, 139–141
(11 September 2003); doi:10.1038/425139a
| Full Text (HTML / PDF) |
letter
Activation of the interferon system by short-interfering RNAs
Carol A. Sledz, Michelle Holko, Michael J. de Veer, Robert H. Silverman and Bryan R.G. Williams
Nature Cell Biology 5, 834–839
(September 2003); doi:10.1038/ncb1038
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news and views
Small-interfering RNAs in the radar of the interferon system
Eric G. Moss and John M. Taylor
Nature Cell Biology 5, 771–772
(September 2003); doi:10.1038/ncb0903-771
| Full Text (HTML/PDF) |
article
The nonimmunoglobulin portion of λ5 mediates cell-autonomous pre-B cell receptor signaling
Kazuo Ohnishi and Fritz Melchers
Nature Immunology 4, 849–856
(September 2003); doi:10.1038/ni959
| Abstract | Full Text (HTML/PDF) |
news and views
How pre-B cells know when they have it right
Mark Schlissel
Nature Immunology 4, 817–819
(September 2003); doi:10.1038/ni0903-817
| Full Text (HTML/PDF) |
review article
Signalling pathways of the TNF superfamily: a double-edged sword
Bharat B. Aggarwal
Nature Reviews Immunology 3, 745–756
(September 2003); doi:10.1038/nri1184
| Abstract | Full Text (HTML / PDF) |
article
Mesenchymal stem cells modified with Akt prevent remodeling and restore performance of infarcted hearts
Abeel A. Mangi, Nicolas Noiseux, Deling Kong, Huamei He, Mojgan Rezvani, Joanne S. Ingwall and Victor J. Dzau
Nature Medicine 9, 1195–1201
(September 2003); doi:10.1038/nm912
| Abstract | Full Text (HTML/PDF) |
news and views
Akt helps stem cells heal the heart
Omer N Koç and Stanton L. Gerson
Nature Medicine 9, 1109–1110
(September 2003); doi:10.1038/nm0903-1109
| Full Text (HTML/PDF) |
article
TGF-β-dependent mechanisms mediate restoration of self-tolerance induced by antibodies to CD3 in overt autoimmune diabetes
Mériam Belghith, Jeffrey A. Bluestone, Samia Barriot, Jérome Mégret, Jean-François Bach and Lucienne Chatenoud
Nature Medicine 9, 1202–1208
(September 2003); doi:10.1038/nm924
| Abstract | Full Text (HTML/PDF) |
article
Cyclin-dependent kinase 2 is essential for meiosis but not for mitotic cell division in mice
Sagrario Ortega, Ignacio Prieto, Junko Odajima, Alberto Martín, Pierre Dubus, Rocio Sotillo, Jose Luis Barbero, Marcos Malumbres and Mariano Barbacid
Nature Genetics 35, 25–31
(September 2003); doi:10.1038/ng1232
| Abstract | Full Text (HTML/PDF) |
news and views
Bared essentials of CDK2 and cyclin E
James M. Roberts and Charles J. Sherr
Nature Genetics 35, 8–9
(September 2003); doi:10.1038/ng1234
| Full Text (HTML/PDF) |
article
Retrograde regulation of synaptic vesicle endocytosis and recycling
Kristina D. Micheva, Jo Ann Buchanan, Ronald W. Holz and Stephen J. Smith
Nature Neuroscience 6, 925–932
(September 2003); doi:10.1038/nn1114
| Abstract | Full Text (HTML/PDF) |
news and views
NO going back
Jane Sullivan
Nature Neuroscience 6, 905–906
(September 2003); doi:10.1038/nn0903-905
| Full Text (HTML/PDF) |
review article
14-3-3 proteins in the nervous system
Daniela Berg , Carsten Holzmann and Olaf Riess
Nature Reviews Neuroscience 4, 752–762
(September 2003); doi:10.1038/nrn1197
| Abstract | Full Text (HTML / PDF) |
research article
Engineering of a macromolecular scaffold to develop specific protease inhibitors
A. Allart Stoop and Charles S. Craik
Nature Biotechnology 21, 1063–1068
(September 2003); doi:10.1038/nbt860
| Abstract | Full Text (HTML/PDF) |
news and views
Two hands (or four) are better than one
Ben M. Dunn and Jörg Bungert
Nature Biotechnology 21, 1019–1021
(September 2003); doi:10.1038/nbt0903-1019
| Full Text (HTML/PDF) |
article
Structural basis for p38α MAP kinase quinazolinone and pyridol-pyrimidine inhibitor specificity
Catherine E Fitzgerald, Sangita B Patel, Joseph W Becker, Patricia M Cameron, Dennis Zaller, Vasilis Bill Pikounis, Stephen J O'Keefe and Giovanna Scapin
Nature Structural Biology 10, 764–769
(September 2003); doi:10.1038/nsb949
| Abstract | Full Text (HTML/PDF) |
letters to nature
Oleylethanolamide regulates feeding and body weight through activation of the nuclear receptor PPAR-α
Jin Fu, Silvana Gaetani, Fariba Oveisi, Jesse Lo Verme, Antonia Serrano, Fernando Rodríguez de Fonseca, Anja Rosengarth, Hartmut Luecke, Barbara Di Giacomo, Giorgio Tarzia and Daniele Piomelli
Nature 425, 90–93
(04 September 2003); doi:10.1038/nature01921
| First Paragraph | Full Text (HTML / PDF) |
letters to nature
Proton-sensing G-protein-coupled receptors
Marie-Gabrielle Ludwig, Miroslava Vanek, Danilo Guerini, Jürg A. Gasser, Carol E. Jones, Uwe Junker, Hans Hofstetter, Romain M. Wolf and Klaus Seuwen
Nature 425, 93–98
(04 September 2003); doi:10.1038/nature01905
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letters to nature
Structure of the catalytic domain of human phosphodiesterase 5 with bound drug molecules
Byung-Je Sung, Kwang Yeon Hwang, Young Ho Jeon, Jae Il Lee, Yong-Seok Heo, Jin Hwan Kim, Jinho Moon, Jung Min Yoon, Young-Lan Hyun, Eunmi Kim, Sung Jin Eum, Sam-Yong Park, Jie-Oh Lee, Tae Gyu Lee, Seonggu Ro and Joong Myung Cho
Nature 425, 98–102
(04 September 2003); doi:10.1038/nature01914
| First Paragraph | Full Text (HTML / PDF) |
article
The endoplasmic reticulum is the site of cholesterol-induced cytotoxicity in macrophages
Bo Feng, Pin Mei Yao, Yankun Li, Cecilia M. Devlin, Dajun Zhang, Heather P. Harding, Michele Sweeney, James X. Rong, George Kuriakose, Edward A. Fisher, Andrew R. Marks, David Ron and Ira Tabas
Nature Cell Biology 5, 781–792
(September 2003); doi:10.1038/ncb1035
| Abstract | Full Text (HTML/PDF) |
news and views
Unfolding the toxicity of cholesterol
Kezhong Zhang and Randal J. Kaufman
Nature Cell Biology 5, 769–770
(September 2003); doi:10.1038/ncb0903-769
| Full Text (HTML/PDF) |
article
Enhanced T cell responses due to diacylglycerol kinase ζ deficiency
Xiao-Ping Zhong, Ehmonie A. Hainey, Benjamin A. Olenchock, Martha S. Jordan, Jonathan S. Maltzman, Kim E. Nichols, Hao Shen and Gary A. Koretzky
Nature Immunology 4, 882–890
(September 2003); doi:10.1038/ni958
| Abstract | Full Text (HTML/PDF) |
article
Crystal structure of HLA-A2 bound to LIR-1, a host and viral major histocompatibility complex receptor
Benjamin E. Willcox, Leonard M. Thomas and Pamela J. Bjorkman
Nature Immunology 4, 913–919
(September 2003); doi:10.1038/ni961
| Abstract | Full Text (HTML/PDF) |
news and views
Boosting p53 with interferon and viruses
Jan Vilcek
Nature Immunology 4, 825–826
(September 2003); doi:10.1038/ni0903-825
| Full Text (HTML/PDF) |
review article
DC-SIGN: escape mechanism for pathogens
Yvette van Kooyk and Teunis B. H. Geijtenbeek
Nature Reviews Immunology 3, 697–709
(September 2003); doi:10.1038/nri1182
| Abstract | Full Text (HTML / PDF) |
article
Glucagon-like peptide-1 receptor is involved in learning and neuroprotection
Matthew J. During, Lei Cao, David S. Zuzga, Jeremy S. Francis, Helen L. Fitzsimons, Xiangyang Jiao, Ross J. Bland, Matthias Klugmann, William A. Banks, Daniel J. Drucker and Colin N. Haile
Nature Medicine 9, 1173–1179
(September 2003); doi:10.1038/nm919
| Abstract | Full Text (HTML/PDF) |
news and views
Learning from the gut
Mark P. Mattson, Tracy Ann Perry and Nigel H. Greig
Nature Medicine 9, 1113–1115
(September 2003); doi:10.1038/nm0903-1113
| Full Text (HTML/PDF) |
review article
The role of FLT3 in haematopoietic malignancies
Derek L. Stirewalt and Jerald P. Radich
Nature Reviews Cancer 3, 650–665
(September 2003); doi:10.1038/nrc1169
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letter
Mutations associated with neutropenia in dogs and humans disrupt intracellular transport of neutrophil elastase
Kathleen F. Benson, Feng-Qian Li, Richard E. Person, Dalila Albani, Zhijun Duan, Jeremy Wechsler, Kimberly Meade-White, Kayleen Williams, Gregory M. Acland, Glenn Niemeyer, Clinton D. Lothrop and Marshall Horwitz
Nature Genetics 35, 90–96
(September 2003); doi:10.1038/ng1224
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brief communication
Small-conductance, Ca2+-activated K+ channel SK3 generates age-related memory and LTP deficits
Thomas Blank, Ingrid Nijholt, Min-Jeong Kye, Jelena Radulovic and Joachim Spiess
Nature Neuroscience 6, 911–912
(September 2003); doi:10.1038/nn1101
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article
Adenylyl cyclase I regulates AMPA receptor trafficking during mouse cortical 'barrel' map development
Hui-Chen Lu, Wei-Chi She, Daniel T. Plas, Paul E. Neumann, Roger Janz and Michael C. Crair
Nature Neuroscience 6, 939–947
(September 2003); doi:10.1038/nn1106
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article
Plasticity of calcium channels in dendritic spines
Ryohei Yasuda, Bernardo L. Sabatini and Karel Svoboda
Nature Neuroscience 6, 948–955
(September 2003); doi:10.1038/nn1112
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review article
The role of α-synuclein in Parkinson's disease: insights from animal models
Eleonora Maries, Biplob Dass, Timothy J. Collier, Jeffrey H. Kordower and Kathy Steece-Collier
Nature Reviews Neuroscience 4, 727–738
(September 2003); doi:10.1038/nrn1199
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research article
Random peptide libraries displayed on adeno-associated virus to select for targeted gene therapy vectors
Oliver J. Müller, Felix Kaul, Matthew D. Weitzman, Renata Pasqualini, Wadih Arap, Jürgen A. Kleinschmidt and Martin Trepel
Nature Biotechnology 21, 1040–1046
(September 2003); doi:10.1038/nbt856
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news and views
AAV display—homing in on the target
André Lieber
Nature Biotechnology 21, 1011–1013
(September 2003); doi:10.1038/nbt0903-1011
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article
Pulling geometry defines the mechanical resistance of a β-sheet protein
David J. Brockwell, Emanuele Paci, Rebecca C. Zinober, Godfrey S. Beddard, Peter D. Olmsted, D. Alastair Smith, Richard N. Perham and Sheena E. Radford
Nature Structural Biology 10, 731–737
(September 2003); doi:10.1038/nsb968
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article
The mechanical stability of ubiquitin is linkage dependent
Mariano Carrion-Vazquez, Hongbin Li, Hui Lu, Piotr E. Marszalek, Andres F. Oberhauser and Julio M. Fernandez
Nature Structural Biology 10, 738–743
(September 2003); doi:10.1038/nsb965
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news and views
Finding a protein's Achilles heel
Andreas Matouschek and Carlos Bustamante
Nature Structural Biology 10, 674–676
(September 2003); doi:10.1038/nsb0903-674
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