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The Research Library categorizes, and provides access to, all recent signaling-related research published in the Nature Publishing Group journals. The selection is deliberately broad to facilitate access to all research impacting on the signaling community. Both primary research and review articles are included, as are 'News and Views' articles.
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article
A gene expression atlas of the central nervous system based on bacterial artificial chromosomes
Shiaoching Gong, Chen Zheng, Martin L. Doughty, Kasia Losos, Nicholas Didkovsky, Uta B. Schambra, Norma J. Nowak, Alexandra Joyner, Gabrielle Leblanc, Mary E. Hatten and Nathaniel Heintz
Nature 425, 917–925
(30 October 2003); doi:10.1038/nature02033
| Abstract | Full Text (HTML / PDF) |
news and views
Molecular neuroscience: BAC-to-BAC images of the brain
Huda Y. Zoghbi
Nature 425, 907–908
(30 October 2003); doi:10.1038/425907a
| Full Text (HTML / PDF) |
article
Motor neuron columnar fate imposed by sequential phases of Hox-c activity
Jeremy S. Dasen, Jeh-Ping Liu and Thomas M. Jessell
Nature 425, 926–933
(30 October 2003); doi:10.1038/nature02051
| Abstract | Full Text (HTML / PDF) |
letters to nature
Positioning of follicular dendritic cells within the spleen controls prion neuroinvasion
Marco Prinz , Mathias Heikenwalder, Tobias Junt, Petra Schwarz, Markus Glatzel, Frank L. Heppner, Yang-Xin Fu, Martin Lipp and Adriano Aguzzi
Nature 425, 957–962
(30 October 2003); doi:10.1038/nature02072
| First Paragraph | Full Text (HTML / PDF) |
letters to nature
Bmi-1 dependence distinguishes neural stem cell self-renewal from progenitor proliferation
Anna V. Molofsky, Ricardo Pardal, Toshihide Iwashita, In-Kyung Park, Michael F. Clarke and Sean J. Morrison
Nature 425, 962–967
(30 October 2003); doi:10.1038/nature02060
| First Paragraph | Full Text (HTML / PDF) |
letters to nature
SNARE-protein-mediated disease resistance at the plant cell wall
Nicholas C. Collins, Hans Thordal-Christensen, Volker Lipka, Stephan Bau, Erich Kombrink, Jin-Long Qiu, Ralph Hückelhoven, Mónica Stein, Andreas Freialdenhoven, Shauna C. Somerville and Paul Schulze-Lefert
Nature 425, 973–977
(30 October 2003); doi:10.1038/nature02076
| First Paragraph | Full Text (HTML / PDF) |
letters to nature
Bone recognition mechanism of porcine osteocalcin from crystal structure
Quyen Q. Hoang, Frank Sicheri, Andrew J. Howard and Daniel S. C. Yang
Nature 425, 977–980
(30 October 2003); doi:10.1038/nature02079
| First Paragraph | Full Text (HTML / PDF) |
letters to nature
ATP-dependent reduction of cysteine-sulphinic acid by S. cerevisiae sulphiredoxin
Benoît Biteau, Jean Labarre and Michel B. Toledano
Nature 425, 980–984
(30 October 2003); doi:10.1038/nature02075
| First Paragraph | Full Text (HTML / PDF) |
letter
LKB1 (XEEK1) regulates Wnt signalling in vertebrate development
Olga Ossipova, Nabeel Bardeesy, Ronald A. DePinho and Jeremy B. A. Green
Nature Cell Biology 5, 889–894
(October 2003); doi:10.1038/ncb1048
| First Paragraph | Full Text (HTML/PDF) |
news and views
Wnt signalling gets XEEKy
Wilson K. Clements and David Kimelman
Nature Cell Biology 5, 861–863
(October 2003); doi:10.1038/ncb1003-861
| Full Text (HTML/PDF) |
letter
Epithelial tube morphogenesis during Drosophila tracheal development requires Piopio, a luminal ZP protein
Anna Jaz´win´ska, Carlos Ribeiro and Markus Affolter
Nature Cell Biology 5, 895–901
(October 2003); doi:10.1038/ncb1049
| First Paragraph | Full Text (HTML/PDF) |
letter
S-phase checkpoint controls mitosis via an APC-independent Cdc20p function
Duncan J. Clarke, Marisa Segal, Catherine A. Andrews, Stanislav G. Rudyak, Sanne Jensen, Karen Smith and Steven I. Reed
Nature Cell Biology 5, 928–935
(October 2003); doi:10.1038/ncb1046
| First Paragraph | Full Text (HTML/PDF) |
news and views
Can Fizzy fly solo?
Peter K. Jackson
Nature Cell Biology 5, 864–865
(October 2003); doi:10.1038/ncb1003-864
| Full Text (HTML/PDF) |
news and views
Timing the cell cycle
Peter K. Jackson
Nature Cell Biology 5, 859–861
(October 2003); doi:10.1038/ncb1003-859
| Full Text (HTML/PDF) |
news and views
From shoot to root
Alison Schuldt
Nature Cell Biology 5, 855
(October 2003); doi:10.1038/ncb1003-855
| Full Text (HTML/PDF) |
review article
The nuclear pore complex: nucleocytoplasmic transport and beyond
Birthe Fahrenkrog and Ueli Aebi
Nature Reviews Molecular Cell Biology 4, 757–766
(October 2003); doi:10.1038/nrm1230
| Abstract | Full Text (HTML / PDF) |
article
LAT regulates γd T cell homeostasis and differentiation
Selene Nuñez-Cruz, Enrique Aguado, Sylvie Richelme, Bruno Chetaille, Anne-Marie Mura, Mireille Richelme, Laurent Pouyet, Evelyne Jouvin-Marche, Luc Xerri, Bernard Malissen and Marie Malissen
Nature Immunology 4, 999–1008
(October 2003); doi:10.1038/ni977
| Abstract | Full Text (HTML/PDF) |
article
Regulation of macrophage and neutrophil cell fates by the PU.1:C/EBPα ratio and granulocyte colony-stimulating factor
Richard Dahl, Jonathan C Walsh, David Lancki, Peter Laslo, Sangeeta R Iyer, Harinder Singh and M Celeste Simon
Nature Immunology 4, 1029–1036
(October 2003); doi:10.1038/ni973
| Abstract | Full Text (HTML/PDF) |
review article
Macrophage migration inhibitory factor: a regulator of innate immunity
Thierry Calandra and Thierry Roger
Nature Reviews Immunology 3, 791–800
(October 2003); doi:10.1038/nri1200
| Abstract | Full Text (HTML / PDF) |
review article
The SAP and SLAM families in immune responses and X-linked lymphoproliferative disease
Pablo Engel, Michael J. Eck and Cox Terhorst
Nature Reviews Immunology 3, 813–821
(October 2003); doi:10.1038/nri1202
| Abstract | Full Text (HTML / PDF) |
article
Fc-dependent depletion of activated T cells occurs through CD40L-specific antibody rather than costimulation blockade
Nicola J Monk, Roseanna E G Hargreaves, James E Marsh, Conrad A Farrar, Steven H Sacks, Maggie Millrain, Elizabeth Simpson, Julian Dyson and Stipo Jurcevic
Nature Medicine 9, 1275–1280
(October 2003); doi:10.1038/nm931
| Abstract | Full Text (HTML/PDF) |
news and views
The new immunosuppression: just kill the T cell
Herman Waldmann
Nature Medicine 9, 1259–1260
(October 2003); doi:10.1038/nm1003-1259
| Full Text (HTML/PDF) |
article
Natural antibodies and complement are endogenous adjuvants for vaccine-induced CD8+ T-cell responses
Simona Stäger, James Alexander, Alun C Kirby, Marina Botto, Nico Van Rooijen, Deborah F Smith, Frank Brombacher and Paul M Kaye
Nature Medicine 9, 1287–1292
(October 2003); doi:10.1038/nm933
| Abstract | Full Text (HTML/PDF) |
letter
T-cell glucocorticoid receptor is required to suppress COX-2-mediated lethal immune activation
Judson A Brewer, Bernard Khor, Sherri K Vogt, Lisa M Muglia, Hideji Fujiwara, Karen E Haegele, Barry P Sleckman and Louis J Muglia
Nature Medicine 9, 1318–1322
(October 2003); doi:10.1038/nm895
| First Paragraph | Full Text (HTML/PDF) |
letter
Inhibition of renal cystic disease development and progression by a vasopressin V2 receptor antagonist
Vincent H Gattone II, Xiaofang Wang, Peter C Harris and Vicente E Torres
Nature Medicine 9, 1323–1326
(October 2003); doi:10.1038/nm935
| First Paragraph | Full Text (HTML/PDF) |
review article
Cannabinoids: potential anticancer agents
Manuel Guzmán
Nature Reviews Cancer 3, 745–755
(October 2003); doi:10.1038/nrc1188
| Abstract | Full Text (HTML / PDF) |
review article
Cancer chemoprevention with dietary phytochemicals
Young-Joon Surh
Nature Reviews Cancer 3, 768–780
(October 2003); doi:10.1038/nrc1189
| Abstract | Full Text (HTML / PDF) |
perspectives
Innovation: New tools for functional mammalian cancer genetics
Thijn R. Brummelkamp and René Bernards
Nature Reviews Cancer 3, 781–789
(October 2003); doi:10.1038/nrc1191
| Abstract | Full Text (HTML / PDF) |
perspectives
Opinion: Proteomic analysis of cancer-cell mitochondria
Mukesh Verma, Jacob Kagan, David Sidransky and Sudhir Srivastava
Nature Reviews Cancer 3, 789–795
(October 2003); doi:10.1038/nrc1192
| Abstract | Full Text (HTML / PDF) |
article
Transcriptome analysis of the acoelomate human parasite Schistosoma mansoni
Sergio Verjovski-Almeida, Ricardo DeMarco, Elizabeth A L Martins, Pedro E M Guimarães, Elida P B Ojopi, Apuã C M Paquola, João P Piazza, Milton Y Nishiyama, Jr. João P Kitajima, Rachel E Adamson, Peter D Ashton, Maria F Bonaldo, Patricia S Coulson, Gary P Dillon, Leonardo P Farias, Sheila P Gregorio, Paulo L Ho, Ricardo A Leite, L Cosme C Malaquias, Regina C P Marques, Patricia A Miyasato, Ana L T O Nascimento, Fernanda P Ohlweiler, Eduardo M Reis, Marcela A Ribeiro, Renata G Sá, Gaëlle C Stukart, M Bento Soares, Cybele Gargioni, Toshie Kawano, Vanderlei Rodrigues, Alda M B N Madeira, R Alan Wilson, Carlos F M Menck, João C Setubal, Luciana C C Leite and Emmanuel Dias-Neto
Nature Genetics 35, 148–157
(October 2003); doi:10.1038/ng1237
| Abstract | Full Text (HTML/PDF) |
letter
A novel ubiquitin ligase is deficient in Fanconi anemia
Amom Ruhikanta Meetei, Johan P de Winter, Annette L Medhurst, Michael Wallisch, Quinten Waisfisz, Henri J van de Vrugt, Anneke B Oostra, Zhijiang Yan, Chen Ling, Colin E Bishop, Maureen E Hoatlin, Hans Joenje and Weidong Wang
Nature Genetics 35, 165–170
(October 2003); doi:10.1038/ng1241
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news and views
FANCL, as in ligase
Markus Grompe
Nature Genetics 35, 113–114
(October 2003); doi:10.1038/ng1003-113
| Full Text (HTML/PDF) |
review article
The genetic basis of mammalian neurulation
Andrew J. Copp, Nicholas D. E. Greene and Jennifer N. Murdoch
Nature Reviews Genetics 4, 784–793
(October 2003); doi:10.1038/nrg1181
| Abstract | Full Text (HTML / PDF) |
article
Limbic corticotropin-releasing hormone receptor 1 mediates anxiety-related behavior and hormonal adaptation to stress
Marianne B Müller, Stephan Zimmermann, Inge Sillaber, Thomas P Hagemeyer, Jan M Deussing, Peter Timpl, Michael S D Kormann, Susanne K Droste, Ralf Kühn, Johannes M H M Reul, Florian Holsboer and Wolfgang Wurst
Nature Neuroscience 6, 1100–1107
(October 2003); doi:10.1038/nn1123
| Abstract | Full Text (HTML/PDF) |
news and views
Dissecting the components of the central response to stress
Emeran A Mayer and Michael S Fanselow
Nature Neuroscience 6, 1011–1012
(October 2003); doi:10.1038/nn1003-1011
| Full Text (HTML/PDF) |
article
Cdk5 activation induces hippocampal CA1 cell death by directly phosphorylating NMDA receptors
Jian Wang, ShuHong Liu, YangPing Fu, Jerry H Wang and YouMing Lu
Nature Neuroscience 6, 1039–1047
(October 2003); doi:10.1038/nn1119
| Abstract | Full Text (HTML/PDF) |
article
Brief presynaptic bursts evoke synapse-specific retrograde inhibition mediated by endogenous cannabinoids
Solange P Brown, Stephan D Brenowitz and Wade G Regehr
Nature Neuroscience 6, 1048–1057
(October 2003); doi:10.1038/nn1126
| Abstract | Full Text (HTML/PDF) |
article
Presynaptic kainate receptors impart an associative property to hippocampal mossy fiber long-term potentiation
Dietmar Schmitz, Jack Mellor, Joerg Breustedt and Roger A Nicoll
Nature Neuroscience 6, 1058–1063
(October 2003); doi:10.1038/nn1116
| Abstract | Full Text (HTML/PDF) |
review article
Neural crest specification: migrating into genomics
Laura S. Gammill and Marianne Bronner-Fraser
Nature Reviews Neuroscience 4, 795–805
(October 2003); doi:10.1038/nrn1219
| Abstract | Full Text (HTML / PDF) |
review article
Cranial neural crest and the building of the vertebrate head
Fabio Santagati and Filippo M. Rijli
Nature Reviews Neuroscience 4, 806–818
(October 2003); doi:10.1038/nrn1221
| Abstract | Full Text (HTML / PDF) |
article
Structure of NFAT1 bound as a dimer to the HIV-1 LTR kB element
Michael J Giffin, James C Stroud, Darren L Bates, Konstanze D von Koenig, John Hardin and Lin Chen
Nature Structural Biology 10, 800–806
(October 2003); doi:10.1038/nsb981
| Abstract | Full Text (HTML/PDF) |
article
The ligand-binding face of the semaphorins revealed by the high-resolution crystal structure of SEMA4D
Christopher A Love, Karl Harlos, Nasim Mavaddat, Simon J Davis, David I Stuart, E Yvonne Jones and Robert M Esnouf
Nature Structural Biology 10, 843–848
(October 2003); doi:10.1038/nsb977
| Abstract | Full Text (HTML/PDF) |
article
Complete structure of p97/valosin-containing protein reveals communication between nucleotide domains
Byron DeLaBarre and Axel T Brunger
Nature Structural Biology 10, 856–863
(October 2003); doi:10.1038/nsb972
| Abstract | Full Text (HTML/PDF) |
review
Soft landing for protein chips
Michael P Washburn
Nature Biotechnology 21, 1156–1157
( 2000); doi:10.1038/nbt1003-1156
| Abstract | Full Text (HTML/PDF) |
review article
HIF-1 as a target for drug development
Amato Giaccia, Bronwyn G. Siim and Randall S. Johnson
Nature Reviews Drug Discovery 2, 803–811
(October 2003); doi:10.1038/nrd1199
| Abstract | Full Text (HTML / PDF) |
letters to nature
A regulatory mutation in IGF2 causes a major QTL effect on muscle growth in the pig
Anne-Sophie Van Laere, Minh Nguyen, Martin Braunschweig, Carine Nezer, Catherine Collette, Laurence Moreau, Alan L. Archibald, Chris S. Haley, Nadine Buys, Michael Tally, Göran Andersson, Michel Georges and Leif Andersson
Nature 425, 832–836
(23 October 2003); doi:10.1038/nature02064
| First Paragraph | Full Text (HTML / PDF) |
news and views
Genetics: Secret of a porkie porker
Chris Gunter
Nature 425, 777–778
(23 October 2003); doi:10.1038/425777b
| Full Text (HTML / PDF) |
letters to nature
Identification of the haematopoietic stem cell niche and control of the niche size
Jiwang Zhang, Chao Niu, Ling Ye, Haiyang Huang, Xi He, Wei-Gang Tong, Jason Ross, Jeff Haug, Teri Johnson, Jian Q. Feng, Stephen Harris, Leanne M. Wiedemann, Yuji Mishina and Linheng Li
Nature 425, 836–841
(23 October 2003); doi:10.1038/nature02041
| First Paragraph | Full Text (HTML / PDF) |
letters to nature
Osteoblastic cells regulate the haematopoietic stem cell niche
L. M. Calvi, G. B. Adams, K. W. Weibrecht, J. M. Weber, D. P. Olson, M. C. Knight, R. P. Martin, E. Schipani, P. Divieti, F. R. Bringhurst, L. A. Milner, H. M. Kronenberg and D. T. Scadden
Nature 425, 841–846
(23 October 2003); doi:10.1038/nature02040
| First Paragraph | Full Text (HTML / PDF) |
news and views
Stem cells: Interactive niches
Ihor R. Lemischka and Kateri A. Moore
Nature 425, 778–779
(23 October 2003); doi:10.1038/425778a
| Full Text (HTML / PDF) |
letters to nature
Widespread requirement for Hedgehog ligand stimulation in growth of digestive tract tumours
David M. Berman , Sunil S. Karhadkar , Anirban Maitra, Rocio Montes de Oca, Meg R. Gerstenblith, Kimberly Briggs, Antony R. Parker, Yutaka Shimada, James R. Eshleman, D. Neil Watkins and Philip A. Beachy
Nature 425, 846–851
(23 October 2003); doi:10.1038/nature01972
| First Paragraph | Full Text (HTML / PDF) |
letters to nature
Hedgehog is an early and late mediator of pancreatic cancer tumorigenesis
Sarah P. Thayer, Marina Pasca di Magliano, Patrick W. Heiser, Corinne M. Nielsen, Drucilla J. Roberts, Gregory Y. Lauwers, Yan Ping Qi, Stephan Gysin, Carlos Fernández-del Castillo, Vijay Yajnik, Bozena Antoniu, Martin McMahon, Andrew L. Warshaw and Matthias Hebrok
Nature 425, 851–856
(23 October 2003); doi:10.1038/nature02009
| First Paragraph | Full Text (HTML / PDF) |
news and views
Cancer: A twist in a hedgehog's tale
Matthew P. Scott
Nature 425, 780–782
(23 October 2003); doi:10.1038/425780a
| Full Text (HTML / PDF) |
letters to nature
Yip3 catalyses the dissociation of endosomal Rab-GDI complexes
Ulf Sivars, Dikran Aivazian and Suzanne R. Pfeffer
Nature 425, 856–859
(23 October 2003); doi:10.1038/nature02057
| First Paragraph | Full Text (HTML / PDF) |
letters to nature
Targets of the cyclin-dependent kinase Cdk1
Jeffrey A. Ubersax, Erika L. Woodbury, Phuong N. Quang, Maria Paraz, Justin D. Blethrow, Kavita Shah, Kevan M. Shokat and David O. Morgan
Nature 425, 859–864
(23 October 2003); doi:10.1038/nature02062
| First Paragraph | Full Text (HTML / PDF) |
letter
Stability and association of Smoothened, Costal2 and Fused with Cubitus interruptus are regulated by Hedgehog
Laurent Ruel, Ralph Rodriguez, Armel Gallet, Laurence Lavenant-Staccini and Pascal P. Thérond
Nature Cell Biology 5, 907–913
(October 2003); doi:10.1038/ncb1052
| Abstract | Full Text (HTML/PDF) |
news and views
Cdc34: cycling on and off the SCF
Lionel Pintard and Matthias Peter
Nature Cell Biology 5, 856–857
(October 2003); doi:10.1038/ncb1003-856
| | Full Text (HTML/PDF) |
letter
The Salvador partner Hippo promotes apoptosis and cell-cycle exit in Drosophila
Sophie Pantalacci, Nicolas Tapon and Pierre Léopold
Nature Cell Biology 5,921–927
(October 2003); doi:10.1038/ncb1051
| Abstract
| Full Text (HTML/PDF) |
review article
Glycosylation regulates Notch signalling
Nicola Haines and Kenneth D. Irvine
Nature Reviews Molecular Cell Biology 4, 786–797
(October 2003); doi:10.1038/nrm1228
| Summary | Full Text (HTML / PDF) |
article
Leukotriene B4 and BLT1 control cytotoxic effector T cell recruitment to inflamed tissues
Katayoon Goodarzi, Mahmoud Goodarzi, Andrew M Tager, Andrew D Luster and Ulrich H von Andrian
Nature Immunology 4, 965–973
(October 2003); doi:10.1038/ni972
| Abstract
| Full Text (HTML/PDF) |
article
Mast cell–dependent migration of effector CD8+ T cells through production of leukotriene B4
Vanessa L Ott, John C Cambier, John Kappler, Philippa Marrack & Bradley J Swanson
Nature Immunology 4,974–981
( 2000); doi:10.1038/ni971
| Abstract
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article
Leukotriene B4 receptor BLT1 mediates early effector T cell recruitment
Andrew M Tager, Shannon K Bromley, Benjamin D Medoff, Sabina A Islam, Scott D Bercury, Erik B Friedrich, Andrew D Carafone, Robert E Gerszten and Andrew D Luster
Nature Immunology 4, 982–990
(October 2003); doi:10.1038/ni970
| Abstract | Full Text (HTML/PDF) |
news and views
BLT for speed
Stephen P Schoenberger
Nature Immunology 4, 937–939
(October 2003); doi:10.1038/ni1003-937
| | Full Text (HTML/PDF) |
letter
Lipoprotein receptor-mediated induction of matrix metalloproteinase by tissue plasminogen activator
Xiaoying Wang, Sun-Ryung Lee, Ken Arai, Seong-Ryong Lee, Kiyoshi Tsuji, G William Rebeck and Eng H Lo
Nature Medicine 9, 1313–1317
(October 2003); doi:10.1038/nm926
| First Paragraph | Full Text (HTML/PDF) |
brief communication
Genetic deficiency in Pparg does not alter development of experimental prostate cancer
Enrique Saez, Peter Olson and Ronald M Evans
Nature Medicine 9, 1265–1266
(October 2003); doi:10.1038/nm928
| First Paragraph | Full Text (HTML/PDF) |
review article
The role of Notch in tumorigenesis: oncogene or tumour suppressor?
Freddy Radtke and Kenneth Raj
Nature Reviews Cancer 3, 756–767
(October 2003); doi:10.1038/nrc1186
| Summary | Full Text (HTML / PDF) |
news and views
Evolution thinks modular
Alessandro Vespignani
Nature Genetics 35, 118–119
(October 2003); doi:10.1038/ng1003-118
| | Full Text (HTML/PDF) |
article
Acute changes in short-term plasticity at synapses with elevated levels of neuronal calcium sensor-1
Tanya Sippy, Alberto Cruz-Martín, Andreas Jeromin and Felix E Schweizer
Nature Neuroscience 6, 1031–1038
(October 2003); doi:10.1038/nn1117
| Abstract | Full Text (HTML/PDF) |
news and views
NCS-1 Stirs Somnolent Synapses
Robert S Zucker
Nature Neuroscience 6, 1006–1008
(October 2003); doi:10.1038/nn1003-1006
| | Full Text (HTML/PDF) |
article
An asymmetric NFAT1 dimer on a pseudo-palindromic kB-like DNA site
Lei Jin, Piotr Sliz, Lin Chen, Fernando Macián, Anjana Rao, Patrick G Hogan and Stephen C Harrison
Nature Structural Biology 10, 807–811
(October 2003); doi:10.1038/nsb975
| Abstract | Full Text (HTML/PDF) |
article
Global analysis of protein localization in budding yeast
Won-Ki Huh, James V. Falvo, Luke C. Gerke, Adam S. Carroll, Russell W. Howson, Jonathan S. Weissman and Erin K. O'Shea
Nature 425, 686–691
(16 October 2003); doi:10.1038/nature02026
| Abstract | Full Text (HTML / PDF) |
letters to nature
Global analysis of protein expression in yeast
Sina Ghaemmaghami, Won-Ki Huh, Kiowa Bower, Russell W. Howson, Archana Belle, Noah Dephoure, Erin K. O'Shea and Jonathan S. Weissman
Nature 425, 737–741
(16 October 2003); doi:10.1038/nature02046
| First Paragraph | Full Text (HTML / PDF) |
news and views
Proteomics: Where's Waldo in yeast?
James A. Wohlschlegel and John R. Yates
Research in yeast provides the tools and benchmarks for a wide sweep of biology. The latest results reveal the most complete picture yet of the levels and locations of protein production in the organism.
Nature 425, 671–672
(16 October 2003); doi:10.1038/425671a
| Full Text (HTML / PDF) |
letters to nature
Loss of Omi mitochondrial protease activity causes the neuromuscular disorder of mnd2 mutant mice
Julie M. Jones, Pinaki Datta, Srinivasa M. Srinivasula, Weizhen Ji, Sanjeev Gupta, ZhiJia Zhang, Erika Davies, György Hajnóczky, Thomas L. Saunders, Margaret L. Van Keuren, Teresa Fernandes-Alnemri, Miriam H. Meisler and Emad S. Alnemri
Nature 425, 721–727
(16 October 2003); doi:10.1038/nature02052
| First Paragraph | Full Text (HTML / PDF) |
letters to nature
Functional cloning of TUG as a regulator of GLUT4 glucose transporter trafficking
Jonathan S. Bogan , Natalie Hendon, Adrienne E. McKee, Tsu-Shuen Tsao and Harvey F. Lodish
Nature 425, 727–733
(16 October 2003); doi:10.1038/nature01989
| First Paragraph | Full Text (HTML / PDF) |
letters to nature
The tobacco aquaporin NtAQP1 is a membrane CO2 pore with physiological functions
Norbert Uehlein, Claudio Lovisolo, Franka Siefritz and Ralf Kaldenhoff
Nature 425, 734–737
(16 October 2003); doi:10.1038/nature02027
| First Paragraph | Full Text (HTML / PDF) |
letter
Hippo promotes proliferation arrest and apoptosis in the Salvador/Warts pathway
Ryan S. Udan, Madhuri Kango-Singh, Riitta Nolo, Chunyao Tao and Georg Halder
Nature Cell Biology 5, 914–920
(October 2003); doi:10.1038/ncb1050
| First Paragraph | Full Text (HTML/PDF) |
news and views
Hippo and its mission for growth control
Hyung Don Ryoo and Hermann Steller
Nature Cell Biology 5, 853–855
(October 2003); doi:10.1038/ncb1003-853
| Full Text (HTML/PDF) |
review article
Cell-death alternative model organisms: why and which?
Pierre Golstein, Laurence Aubry and Jean-Pierre Levraud
Nature Reviews Molecular Cell Biology 4, 798–807
(October 2003); doi:10.1038/nrm1224
| Abstract | Full Text (HTML / PDF) |
article
Sustained exposure to bacterial antigen induces interferon-γ-dependent T cell receptor ζ down-regulation and impaired T cell function
Noemí Bronstein-Sitton, Leonor Cohen-Daniel, Ilan Vaknin, Analía V Ezernitchi, Benny Leshem, Amal Halabi, Yael Houri-Hadad, Eugenia Greenbaum, Zichria Zakay-Rones, Lior Shapira and Michal Baniyash
Nature Immunology 4, 957–964
(October 2003); doi:10.1038/ni975
| Abstract | Full Text (HTML/PDF) |
news and views
Unplugging the T cell receptor
Guido Poli and Claudio Bordignon
Nature Immunology 4, 943–944
(October 2003); doi:10.1038/ni1003-943
| Full Text (HTML/PDF) |
article
β1-adrenergic receptor polymorphisms confer differential function and predisposition to heart failure
Jeanne Mialet Perez, Deborah A Rathz, Natalia N Petrashevskaya, Harvey S Hahn, Lynne E Wagoner, Arnold Schwartz, Gerald W Dorn II and Stephen B Liggett
Nature Medicine 9, 1300–1305
(October 2003); doi:10.1038/nm930
| Abstract | Full Text (HTML/PDF) |
news and views
β-receptor polymorphisms: heart failure's crystal ball
David A Kass
Nature Medicine 9, 1260–1262
(October 2003); doi:10.1038/nm1003-1260
| Full Text (HTML/PDF) |
review article
Mechanisms of sarcoma development
Lee J. Helman and Paul Meltzer
Nature Reviews Cancer 3, 685–694
(September 2003); doi:10.1038/nrc1168
| Abstract | Full Text (HTML / PDF) |
article
Spontaneous activity of opsin apoprotein is a cause of Leber congenital amaurosis
Michael L Woodruff, Zhongyan Wang, Hae Yun Chung, T Michael Redmond, Gordon L Fain and Janis Lem
Nature Genetics 35, 158–164
(October 2003); doi:10.1038/ng1246
| Abstract | Full Text (HTML/PDF) |
news and views
The dangers of seeing light in the dark
Charlotte E Remé and Andreas Wenzel
Nature Genetics 35, 115–116
(October 2003); doi:10.1038/ng1003-115
| Full Text (HTML/PDF) |
review article
From developmental disorder to heritable cancer: it's all in the BMP/TGF-β family
Kristin A. Waite and Charis Eng
Nature Reviews Genetics 4, 763–773
(October 2003); doi:10.1038/nrg1178
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article
Defects in synaptic vesicle docking in unc-18 mutants
Robby M Weimer, Janet E Richmond, Warren S Davis, Gayla Hadwiger, Michael L Nonet and Erik M Jorgensen
Nature Neuroscience 6, 1023–1030
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NF-kB functions in synaptic signaling and behavior
Mollie K Meffert, Jolene M Chang, Brian J Wiltgen, Michael S Fanselow and David Baltimore
Nature Neuroscience 6, 1072–1078
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Phenotypic alteration of eukaryotic cells using randomized libraries of artificial transcription factors
Kyung-Soon Park, Dong-ki Lee, Horim Lee, Yangsoon Lee, Young-Soon Jang, Yong Ha Kim, Hyo-Young Yang, Sung-I Lee, Wongi Seol1 & Jin-Soo Kim
Nature Biotechnology 21, 1208–1214
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Plant recognition of symbiotic bacteria requires two LysM receptor-like kinases
Simona Radutoiu, Lene Heegaard Madsen, Esben Bjørn Madsen, Hubert H. Felle, Yosuke Umehara, Mette Grønlund, Shusei Sato, Yasukazu Nakamura, Satoshi Tabata, Niels Sandal and Jens Stougaard
Nature 425, 585–592
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letters to nature
A receptor kinase gene of the LysM type is involved in legumeperception of rhizobial signals
Esben Bjørn Madsen, Lene Heegaard Madsen, Simona Radutoiu, Magdalena Olbryt, Magdalena Rakwalska, Krzysztof Szczyglowski, Shusei Sato, Takakazu Kaneko, Satoshi Tabata, Niels Sandal and Jens Stougaard
Nature 425, 637–640
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news and views
Plant biology: Locks, keys and symbioses
Martin Parniske and J. Allan Downie
Nature 425, 569–570
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letters to nature
The Wnt/β-catenin pathway regulates cardiac valve formation
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Nature 425, 633–637
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news and views
Neurobiology: Double trouble for neurons
Mark E. Fortini
Nature 425, 565–566
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Smad-dependent and Smad-independent pathways in TGF-β family signalling
Rik Derynck and Ying E. Zhang
Nature 425, 577–584
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Involvement of CFTR in uterine bicarbonate secretion and the fertilizing capacity of sperm
Xiao Fei Wang, Chen Xi Zhou, Qi Xian Shi, Yu Ying Yuan, Mei Kuen Yu, Louis Chukwuemeka Ajonuma, Lok Sze Ho, Pui Shan Lo, Lai Ling Tsang, Yu Liu, Sun Yi Lam, Ling Nga Chan, Wen Chao Zhao, Yiu Wa Chung and Hsiao Chang Chan
Nature Cell Biology 5, 902–906
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Of fertility, cystic fibrosis and the bicarbonate ion
Keith A. Sutton, Melissa K. Jungnickel and Harvey M. Florman
Nature Cell Biology 5, 857–859
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perspectives
Opinion: Can transcription factors function as cell-cell signalling molecules?
Alain Prochiantz and Alain Joliot
Nature Reviews Molecular Cell Biology 4, 814–819
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Cross-priming of CD8+ T cells stimulated by virus-induced type I interferon
Agnes Le Bon, Nathalie Etchart, Cornelia Rossmann, Miranda Ashton, Sam Hou, Dirk Gewert, Persephone Borrow and David F Tough
Nature Immunology 4, 1009–1015
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Type I interferons promote cross-priming: more functions for old cytokines
Anne-Sophie Beignon, Mojca Skoberne and Nina Bhardwaj
Nature Immunology 4, 939–941
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Plasma-cell homing
Eric J. Kunkel and Eugene C. Butcher
Nature Reviews Immunology 3, 822–829
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Identification of PDGFR as a receptor for AAV-5 transduction
Giovanni Di Pasquale, Beverly L. Davidson, Colleen S. Stein, Inês Martins, Dominic Scudiero, Anne Monks and John A. Chiorini
Nature Medicine 9, 1306–1312
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HIV's great escape
Mark Marsh and Markus Thali
Nature Medicine 9, 1262–1263
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Targeting HIF-1 for cancer therapy
Gregg L. Semenza
Nature Reviews Cancer 3, 721–732
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Evolutionary conservation of motif constituents in the yeast protein interaction network
S Wuchty, Z. N. Oltvai and A-L. Barabási
Nature Genetics 35, 176–179
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HIV-induced metalloproteinase processing of the chemokine stromal cell derived factor-1 causes neurodegeneration
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Nature Neuroscience 6, 1064–1071
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Snip-snip, kill-kill: truncated SDF-1 and HIV-associated neurodegeneration
Richard M. Ransohoff
Nature Neuroscience 6, 1009–1011
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Eat your proteins—live longer
Evelyn Jabri
Nature Structural Biology 10, 780
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perspectives
Innovation: Target discovery
Mark A. Lindsay
Nature Reviews Drug Discovery 2, 831–838
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letters to nature
Jelly belly protein activates the receptor tyrosine kinase Alk to specify visceral muscle pioneers
Hsiu-Hsiang Lee, Audra Norris, Joseph B. Weiss and Manfred Frasch
Nature 425, 507–512
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letters to nature
Jeb signals through the Alk receptor tyrosine kinase to drive visceral muscle fusion
Camilla Englund, Christina E. Lorén, Caroline Grabbe, Gaurav K. Varshney, Fabienne Deleuil, Bengt Hallberg and Ruth H. Palmer
Nature 425, 512–516
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Developmental biology: Partners united
Matthew Freeman
Nature 425, 468–469
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letters to nature
Molecular identification of a danger signal that alerts the immune system to dying cells
Yan Shi, James E. Evans and Kenneth L. Rock
Nature 425, 516–521
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Immunology: Dangerous liaisons
William R. Heath and Francis R. Carbone
Nature 425, 460–461
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letters to nature
Differential regulation of EIN3 stability by glucose and ethylene signalling in plants
Shuichi Yanagisawa, Sang-Dong Yoo and Jen Sheen
Nature 425, 521–525
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letters to nature
Role of visual pigment properties in rod and cone phototransduction
Vladimir Kefalov, Yingbin Fu, Nicholas Marsh-Armstrong and King-Wai Yau
Nature 425, 526–531
(02 October 2003); doi:10.1038/nature01992
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letters to nature
Haem can bind to and inhibit mammalian calcium-dependent Slo1 BK channels
Xiang Dong Tang, Rong Xu, Mark F. Reynolds, Maria L. Garcia, Stefan H. Heinemann and Toshinori Hoshi
Nature 425, 531–535
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Developmental biology: Twisting the body into shape
Ian C. Scott and Didier Y. R. Stainier
Nature 425, 461–463
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Neurobiology: Backchat at the synapse
Patricia C. Salinas
Nature 425, 464–467
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Cell biology: The hippo hypothesis
Michael E. Rothenberg and Yuh-Nung Jan
Nature 425, 469–470
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EphB-ephrinB bi-directional endocytosis terminates adhesion allowing contact mediated repulsion
Manuel Zimmer, Amparo Palmer, Jenny Köhler and Rüdiger Klein
Nature Cell Biology 5, 869–878
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Rac-dependent trans-endocytosis of ephrinBs regulates Eph-ephrin contact repulsion
Daniel J. Marston, Sarah Dickinson and Catherine D. Nobes
Nature Cell Biology 5, 879–888
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How attraction turns to repulsion
David G. Wilkinson
Nature Cell Biology 5, 851–853
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Ras GTPases: integrins' friends or foes?
Kayoko Kinbara, Lawrence E. Goldfinger, Malene Hansen, Fan-Li Chou and Mark H. Ginsberg
Nature Reviews Molecular Cell Biology 4, 767–778
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Caspase-3 regulates cell cycle in B cells: a consequence of substrate specificity
Minna Woo, Razqallah Hakem, Caren Furlonger, Anne Hakem, Gordon S. Duncan, Takehiko Sasaki, Denis Bouchard, Liwei Lu, Gillian E. Wu, Christopher J. Paige and Tak W. Mak
Nature Immunology 4, 1016–1022
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The ins and outs of cross-presentation
Kenneth L. Rock
Nature Immunology 4, 941–943
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Timeline: Individuality: the barrier to optimal immunosuppression
Barry D. Kahan
Nature Reviews Immunology 3, 831–838
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Pharmacologic inactivation of kinase suppressor of ras-1 abrogates Ras-mediated pancreatic cancer
H. Rosie Xing, Carlos Cordon-Cardo, Xinzhu Deng, William Tong, Luis Campodonico, Zvi Fuks and Richard Kolesnick
Nature Medicine 9, 1267–1268
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Differential requirement for CD18 in T-helper effector homing
Seung-Hyo Lee, Joseph E. Prince, Muhammad Rais, Farrah Kheradmand, Felix Shardonofsky, Huifang Lu, Arthur L. Beaudet, C. Wayne Smith, Lynn Soong and David B. Corry
Nature Medicine 9, 1281–1286
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The gene encoding phosphodiesterase 4D confers risk of ischemic stroke
Solveig Gretarsdottir, Gudmar Thorleifsson, Sigridur Th Reynisdottir, Andrei Manolescu, Sif Jonsdottir, Thorbjörg Jonsdottir, Thorunn Gudmundsdottir, Sigrun M. Bjarnadottir, Olafur B. Einarsson, Herdis M. Gudjonsdottir, Malcolm Hawkins, Gudmundur Gudmundsson, Hrefna Gudmundsdottir, Hjalti Andrason, Asta S. Gudmundsdottir, Matthildur Sigurdardottir, Thomas T. Chou, Joseph Nahmias, Shyamali Goss, Sigurlaug Sveinbjörnsdottir, Einar M. Valdimarsson, Finnbogi Jakobsson, Uggi Agnarsson, Vilmundur Gudnason, Gudmundur Thorgeirsson, Jurgen Fingerle, Mark Gurney, Daniel Gudbjartsson, Michael L. Frigge, Augustine Kong, Kari Stefansson and Jeffrey R. Gulcher
Nature Genetics 35, 131–138
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Genetics of common polygenic stroke
Anna F. Dominiczak and Martin W. McBride
Nature Genetics 35, 116–117
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Regulation of acetylcholine receptor clustering by the tumor suppressor APC
Junmei Wang, Zheng Jing, Lili Zhang, Guangdou Zhou, Joe Braun, Yun Yao and Zuo-Zhong Wang
Nature Neuroscience 6, 1017–1018
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All-trans retinoic acid is a ligand for the orphan nuclear receptor RORβ
Catherine Stehlin-Gaon, Dominica Willmann, Denis Zeyer, Sarah Sanglier, Alain Van Dorsselaer, Jean-Paul Renaud, Dino Moras and Roland Schüle
Nature Structural Biology 10, 820–825
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