The Research Library categorizes, and provides access to, all recent signaling-related research published in the Nature Publishing Group journals. The selection is deliberately broad to facilitate access to all research impacting on the signaling community. Both primary research and review articles are included, as are 'News and Views' articles.
Click here for free access to the 'Featured Articles' section, with new articles every week.
article Secondary active transport mediated by a prokaryotic homologue of ClC Cl- channels
Alessio Accardi and Christopher Miller Nature427, 803–807
(26 February 2004); doi:10.1038/nature02314
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news and views Ion transport: Spot the difference
David C. Gadsby Nature427, 795–797
(26 February 2004); doi:10.1038/427795a
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letters to nature Sortilin is essential for proNGF-induced neuronal cell death
Anders Nykjaer, Ramee Lee, Kenneth K. Teng, Pernille Jansen, Peder Madsen, Morten S. Nielsen, Christian Jacobsen, Marco Kliemannel, Elisabeth Schwarz, Thomas E. Willnow, Barbara L. Hempstead and Claus M. Petersen Nature427, 843–848
(26 February 2004); doi:10.1038/nature02319
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news and views Neurobiology: A move to sort life from death
David R. Kaplan and Freda D. Miller Nature427, 798–799
(26 February 2004); doi:10.1038/427798a
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letters to nature The large-conductance Ca2+-activated K+ channel is essential for innate immunity
Jatinder Ahluwalia, Andrew Tinker, Lucie H. Clapp, Michael R. Duchen, Andrey Y. Abramov, Simon Pope, Muriel Nobles and Anthony W. Segal Nature427, 853–858
(26 February 2004); doi:10.1038/nature02356
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letters to nature OXI1 kinase is necessary for oxidative burst-mediated signalling in Arabidopsis
Maike C. Rentel, David Lecourieux, Fatma Ouaked, Sarah L. Usher, Lindsay Petersen, Haruko Okamoto, Heather Knight, Scott C. Peck, Claire S. Grierson, Heribert Hirt and Marc R. Knight Nature427, 858–861
(26 February 2004); doi:10.1038/nature02353
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brief communication Glutamate receptors: RNA editing and death of motor neurons
Yukio Kawahara, Kyoko Ito, Hui Sun, Hitoshi Aizawa, Ichiro Kanazawa and Shin Kwak Nature427, 801
(26 February 2004); doi:10.1038/427801a
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news and views Turning the key on p53
David P. Lane and Peter M. Fischer Nature427, 789–790
(26 February 2004); doi:10.1038/427789a
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letter Protein kinase D regulates basolateral membrane protein exit from trans-Golgi network
Charles Yeaman, M. Inmaculada Ayala, Jessica R. Wright, Frederic Bard, Carine Bossard, Agnes Ang, Yusuke Maeda, Thomas Seufferlein, Ira Mellman, W. James Nelson and Vivek Malhotra Nature Cell Biology6, 106–112
(February 2004); doi:10.1038/ncb1090
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letter ASC is a Bax adaptor and regulates the p53-Bax mitochondrial apoptosis pathway
Takao Ohtsuka, Hoon Ryu, Yohji A. Minamishima, Salvador Macip, Junji Sagara, Keiichi I. Nakayama, Stuart A. Aaronson and Sam W. Lee Nature Cell Biology6, 121–128
(February 2004); doi:10.1038/ncb1087
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review article The dynamin superfamily: universal membrane tubulation and fission molecules?
Gerrit J. K. Praefcke and Harvey T. McMahon Nature Reviews Molecular Cell Biology5, 133–147
(February 2004); doi:10.1038/nrm1313
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article Saposin C is required for lipid presentation by human CD1b
Florian Winau, Vera Schwierzeck, Robert Hurwitz, Natascha Remmel, Peter A Sieling, Robert L Modlin, Steven A Porcelli, Volker Brinkmann, Masahiko Sugita, Konrad Sandhoff, Stefan H E Kaufmann and Ulrich E Schaible Nature Immunology5, 169–174
(February 2004); doi:10.1038/ni1035
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article Saposins facilitate CD1d-restricted presentation of an exogenous lipid antigen to T cells
Suk-Jo Kang and Peter Cresswell Nature Immunology5, 175–181
(February 2004); doi:10.1038/ni1034
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news and views Presenting fats with SAPs
Mitchell Kronenberg Nature Immunology5, 126–127
(February 2004); doi:10.1038/ni0204-126
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article TLR9 signals after translocating from the ER to CpG DNA in the lysosome
Eicke Latz, Annett Schoenemeyer, Alberto Visintin, Katherine A Fitzgerald, Brian G Monks, Cathrine F Knetter, Egil Lien, Nadra J Nilsen, Terje Espevik and Douglas T Golenbock Nature Immunology5, 190–198
(February 2004); doi:10.1038/ni1028
| Abstract | Full Text (HTML/PDF) |
review article Human antibody-Fc receptor interactions illuminated by crystal structures
Jenny M. Woof and Dennis R. Burton Nature Reviews Immunology4, 89–99
(February 2004); doi:10.1038/nri1266
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review article The many important facets of T-cell repertoire diversity
Janko Nikolich-Zugich, Mark K. Slifka and Ilhem Messaoudi Nature Reviews Immunology4, 123–132
(February 2004); doi:10.1038/nri1292
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article PAF-mediated pulmonary edema: a new role for acid sphingomyelinase and ceramide
Rolf Göggel, Supandi Winoto-Morbach, Gabriele Vielhaber, Yumiko Imai, Karsten Lindner, Lore Brade, Helmut Brade, Stefan Ehlers, Arthur S Slutsky, Stefan Schütze, Erich Gulbins and Stefan Uhlig Nature Medicine10, 155–160
(February 2004); doi:10.1038/nm977
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news and views Ceramide lances the lungs
Peter J Barnes Nature Medicine10, 130–131
(February 2004); doi:10.1038/nm0204-130
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article Therapeutic effects of lysophosphatidylcholine in experimental sepsis
Ji-Jing Yan, Jun-Sub Jung, Jung-Eun Lee, Jongho Lee, Sung-Oh Huh, Hee-Sung Kim, Kyeong Cheon Jung, Jae-Young Cho, Ju-Suk Nam, Hong-Won Suh, Yung-Hi Kim and Dong-Keun Song Nature Medicine10, 161–167
(February 2004); doi:10.1038/nm989
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news and views Lipid unites disparate syndromes of sepsis
Haichao Wang, Christopher J Czura and Kevin J Tracey Nature Medicine10, 124–125
(February 2004); doi:10.1038/nm0204-124
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perspectives Opinion: Radiation-induced bystander effects — implications for cancer
Colin B. Seymour and Carmel Mothersill Nature Reviews Cancer4, 158–164
(February 2004); doi:10.1038/nrc1277
| Abstract | Full Text (HTML / PDF) |
letter Repression of AGAMOUS-LIKE 24 is a crucial step in promoting flower development
Hao Yu, Toshiro Ito, Frank Wellmer and Elliot M Meyerowitz Nature Genetics36, 157–161
(February 2004); doi:10.1038/ng1286
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letter A direct functional link between the multi-PDZ domain protein GRIP1 and the Fraser syndrome protein Fras1
Kogo Takamiya, Vassiliki Kostourou, Susanne Adams, Shalini Jadeja, Georges Chalepakis, Peter J Scambler, Richard L Huganir and Ralf H Adams Nature Genetics36, 172–177
(February 2004); doi:10.1038/ng1292
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review article Using human neural stem cells to model neurological disease
Rebekah J. Jakel , Bernard L. Schneider and Clive N. Svendsen Nature Reviews Genetics5, 136–144
(February 2004); doi:10.1038/nrg1268
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article Biochemical and genetic interaction between the fragile X mental retardation protein and the microRNA pathway
Peng Jin, Daniela C Zarnescu, Stephanie Ceman, Mika Nakamoto, Julie Mowrey, Thomas A Jongens, David L Nelson, Kevin Moses and Stephen T Warren Nature Neuroscience7, 113–117
(February 2004); doi:10.1038/nn1174
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article Agonist-independent modulation of N-type calcium channels by ORL1 receptors
Aaron M Beedle, John E McRory, Olivier Poirot, Clinton J Doering, Christophe Altier, Christian Barrere, Jawed Hamid, Joel Nargeot, Emmanuel Bourinet and Gerald W Zamponi Nature Neuroscience7, 118–125
(February 2004); doi:10.1038/nn1180
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article LTP is accompanied by an enhanced local excitability of pyramidal neuron dendrites
Andreas Frick, Jeffrey Magee and Daniel Johnston Nature Neuroscience7, 126–135
(February 2004); doi:10.1038/nn1178
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news and views Storing memories in dendritic channels
Michael Häusser Nature Neuroscience7, 98–100
(February 2004); doi:10.1038/nn0204-98
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review article Presynaptic ionotropic receptors and control of transmitter release
Holly S. Engelman and Amy B. MacDermott Nature Reviews Neuroscience5, 135–145
(February 2004); doi:10.1038/nrn1297
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research article The HUPO PSI's Molecular Interaction format—a community standard for the representation of protein interaction data
Henning Hermjakob, Luisa Montecchi-Palazzi, Gary Bader, Jérôme Wojcik, Lukasz Salwinski, Arnaud Ceol, Susan Moore, Sandra Orchard, Ugis Sarkans, Christian von Mering, Bernd Roechert, Sylvain Poux, Eva Jung, Henning Mersch, Paul Kersey, Michael Lappe, Yixue Li, Rong Zeng, Debashis Rana, Macha Nikolski, Holger Husi, Christine Brun, K Shanker, Seth G N Grant, Chris Sander, Peer Bork, Weimin Zhu, Akhilesh Pandey, Alvis Brazma, Bernard Jacq, Marc Vidal, David Sherman, Pierre Legrain, Gianni Cesareni, Ioannis Xenarios, David Eisenberg, Boris Steipe, Chris Hogue and Rolf Apweiler Nature Biotechnology22, 177–183
(February 2004); doi:10.1038/nbt926
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article A short peptide insertion crucial for angiostatic activity of human tryptophanyl-tRNA synthetase
Yoshiaki Kise, Sang Won Lee, Sang Gyu Park, Shuya Fukai, Toru Sengoku, Ryohei Ishii, Shigeyuki Yokoyama, Sunghoon Kim and Osamu Nureki Nature Structural and Molecular Biology11, 149–156
(February 2004); doi:10.1038/nsmb722
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letters to nature Multistability in the lactose utilization network of Escherichia coli
Ertugrul M. Ozbudak, Mukund Thattai, Han N. Lim, Boris I. Shraiman and Alexander van Oudenaarden Nature427, 737–740
(19 February 2004); doi:10.1038/nature02298
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letters to nature Direct interaction of geminin and Six3 in eye development
Filippo Del Bene, Kristin Tessmar-Raible and Joachim Wittbrodt Nature427, 745–749
(19 February 2004); doi:10.1038/nature02292
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letters to nature The cell-cycle regulator geminin inhibits Hox function through direct and polycomb-mediated interactions
Lingfei Luo, Xiaoping Yang, Yoshihiro Takihara, Hendrik Knoetgen and Michael Kessel Nature427, 749–753
(19 February 2004); doi:10.1038/nature02305
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news and views Transcription: Origins of licensing control
Xue Li and Michael G. Rosenfeld Nature427, 687–688
(19 February 2004); doi:10.1038/427687a
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brief communication Pathology: Cancer cells compress intratumour vessels
Timothy P. Padera, Brian R. Stoll, Jessica B. Tooredman, Diane Capen, Emmanuelle di Tomaso and Rakesh K. Jain Nature427, 695
(19 February 2004); doi:10.1038/427695a
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letter The tumour suppressor RASSF1A regulates mitosis by inhibiting the APC-Cdc20 complex
Min Sup Song, Su Jeong Song, Nagi G. Ayad, Jin Sook Chang, Joo Hyun Lee, Hyun Kyung Hong, Ho Lee, Naeyun Choi, Jhingook Kim, Hojoong Kim, Jin Woo Kim, Eui-Ju Choi, Marc W. Kirschner and Dae-Sik Lim Nature Cell Biology6, 129–137
(February 2004); doi:10.1038/ncb1091
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letter Gadd45β mediates the NF-kB suppression of JNK signalling by targeting MKK7/JNKK2
Salvatore Papa, Francesca Zazzeroni, Concetta Bubici, Shanthi Jayawardena, Kellean Alvarez, Shuji Matsuda, Dung U. Nguyen, Can G. Pham, Andreas H. Nelsbach, Tiziana Melis, Enrico De Smaele, Wei-Jen Tang, Luciano D'Adamio and Guido Franzoso Nature Cell Biology6, 146–153
(February 2004); doi:10.1038/ncb1093
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news and views Security measures at the nuclear pore
Alison Schuldt Nature Cell Biology6, 91
(February 2004); doi:10.1038/ncb0204-91
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review article Sorting GPI-anchored proteins
Satyajit Mayor and Howard Riezman Nature Reviews Molecular Cell Biology5, 110–120
(February 2004); doi:10.1038/nrm1309
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article Priming of naive T cells inside tumors leads to eradication of established tumors
Ping Yu, Youjin Lee, Wenhua Liu, Robert K Chin, Jing Wang, Yang Wang, Andrea Schietinger, Mary Philip, Hans Schreiber and Yang-Xin Fu Nature Immunology5, 141–149
(February 2004); doi:10.1038/ni1029
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news and views LIGHTing the way for tumor immunity
Alan N Houghton Nature Immunology5, 123–124
(February 2004); doi:10.1038/ni0204-123
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article The costimulation-regulated duration of PKB activation controls T cell longevity
Jianxun Song, Shahram Salek-Ardakani, Paul R Rogers, Mary Cheng, Luk Van Parijs and Michael Croft Nature Immunology5, 150–158
(February 2004); doi:10.1038/ni1030
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review article p47 GTPases: regulators of immunity to intracellular pathogens
Gregory A. Taylor, Carl G. Feng and Alan Sher Nature Reviews Immunology4, 100–109
(February 2004); doi:10.1038/nri1270
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letter A MARCKS-related peptide blocks mucus hypersecretion in a mouse model of asthma
Monique Singer, Linda D Martin, B Boris Vargaftig, Joungjoa Park, Achim D Gruber, Yuehua Li and Kenneth B Adler Nature Medicine10, 193–196
(February 2004); doi:10.1038/nm983
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article Expression profiling identifies the cytoskeletal organizer ezrin and the developmental homeoprotein Six-1 as key metastatic regulators
Yanlin Yu, Javed Khan, Chand Khanna, Lee Helman, Paul S Meltzer and Glenn Merlino Nature Medicine10, 175–181
(February 2004); doi:10.1038/nm966
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review article Nuclear transport and cancer: from mechanism to intervention
Tweeny R. Kau , Jeffrey C. Way and Pamela A. Silver Nature Reviews Cancer4, 106–117
(February 2004); doi:10.1038/nrc1274
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article Convergent evidence for impaired AKT1-GSK3β signaling in schizophrenia
Effat S Emamian, Diana Hall, Morris J Birnbaum, Maria Karayiorgou and Joseph A Gogos Nature Genetics36, 131–137
(February 2004); doi:10.1038/ng1296
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news and views Getting our AKT together in schizophrenia?
Joachim Hallmayer Nature Genetics36, 115–116
(February 2004); doi:10.1038/ng0204-115
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perspectives Innovation: TILLING — a high-throughput harvest for functional genomics
Derek L. Stemple Nature Reviews Genetics5, 145–150
(February 2004); doi:10.1038/nrg1273
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article Bi-directional effects of GABAB receptor agonists on the mesolimbic dopamine system
Hans G Cruz, Tatiana Ivanova, Marie-Louise Lunn, Markus Stoffel, Paul A Slesinger and Christian Lüscher Nature Neuroscience7, 153–159
(February 2004); doi:10.1038/nn1181
| Abstract | Full Text (HTML/PDF) |
perspectives Localized striatal delivery of GDNF as a treatment for Parkinson disease
Deniz Kirik, Biljana Georgievska and Anders Björklund Nature Neuroscience7, 105–110
(February 2004); doi:10.1038/nn1175
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news and views Label-free detection becomes crystal clear
Paul S Cremer Nature Biotechnology22, 172–173
(February 2004); doi:10.1038/nbt0204-172
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review article Oxygen therapeutics: can we tame haemoglobin?
Abdu I. Alayash Nature Reviews Drug Discovery3, 152–159
(February 2004); doi:10.1038/nrd1307
| Abstract | Full Text (HTML / PDF) |
letters to nature Identification of an angiogenic factor that when mutated causes susceptibility to Klippel-Trenaunay syndrome
Xiao-Li Tian, Rajkumar Kadaba, Sun-Ah You, Mugen Liu , Ayse Anil Timur, Lin Yang, Qiuyun Chen, Przemyslaw Szafranski, Shaoqi Rao, Ling Wu, David E. Housman, Paul E. DiCorleto, David J. Driscoll, Julian Borrow and Qing Wang Nature427, 640–645
(12 February 2004); doi:10.1038/nature02320
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news and views Medicine: Genetic spotlight on a blood defect
Diether Lambrechts and Peter Carmeliet Nature427, 592–594
(12 February 2004); doi:10.1038/427592a
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brief communication Evolutionary genetics: CCR5 mutation and plague protection
Joan Mecsas, Greg Franklin, William A. Kuziel, Robert R. Brubaker, Stanley Falkow and Donald E. Mosier Nature427, 606
(12 February 2004); doi:10.1038/427606a
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letter The DNA damage checkpoint and PKA pathways converge on APC substrates and Cdc20 to regulate mitotic progression
Jennifer S. Searle, Kaila L. Schollaert, Benjamin J. Wilkins and Yolanda Sanchez Nature Cell Biology6, 138–145
(February 2004); doi:10.1038/ncb1092
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letter FAK-Src signalling through paxillin, ERK and MLCK regulates adhesion disassembly
Donna J. Webb, Karen Donais, Leanna A. Whitmore, Sheila M. Thomas, Christopher E. Turner, J. Thomas Parsons and Alan F. Horwitz Nature Cell Biology6, 154–161
(February 2004); doi:10.1038/ncb1094
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news and views Modifiying NEMO
Ronald T. Hay Nature Cell Biology6, 89–91
(February 2004); doi:10.1038/ncb0204-89
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review article Endocytic recycling
Frederick R. Maxfield and Timothy E. McGraw Nature Reviews Molecular Cell Biology5, 121–132
(February 2004); doi:10.1038/nrm1315
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article Ligand-independent redistribution of Fas (CD95) into lipid rafts mediates clonotypic T cell death
Jagan R Muppidi and Richard M Siegel Nature Immunology5, 182–189
(February 2004); doi:10.1038/ni1024
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news and views Right place, right time
Christopher J Froelich Nature Immunology5, 124–125
(February 2004); doi:10.1038/ni0204-124
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article Identification of amino acid residues crucial for chemokine receptor dimerization
Patricia Hernanz-Falcón, José Miguel Rodríguez-Frade, Antonio Serrano, David Juan, Antonio del Sol, Silvia F Soriano, Fernando Roncal, Lucio Gómez, Alfonso Valencia, Carlos Martínez-A and Mario Mellado Nature Immunology5, 216–223
(February 2004); doi:10.1038/ni1027
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review article The dark side of C5a in sepsis
Peter A. Ward Nature Reviews Immunology4, 133–142
(February 2004); doi:10.1038/nri1269
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article Role of STAT-3 in regulation of hepatic gluconeogenic genes and carbohydrate metabolism in vivo
Hiroshi Inoue, Wataru Ogawa, Michitaka Ozaki, Sanae Haga, Michihiro Matsumoto, Kensuke Furukawa, Naoko Hashimoto, Yoshiaki Kido, Toshiyuki Mori, Hiroshi Sakaue, Kiyoshi Teshigawara, Shiyu Jin, Haruhisa Iguchi, Ryuji Hiramatsu, Derek LeRoith, Kiyoshi Takeda, Shizuo Akira and Masato Kasuga Nature Medicine10, 168–174
(February 2004); doi:10.1038/nm980
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news and views EMSY, a BRCA-2 partner in crime
David M Livingston Nature Medicine10, 127–128
(February 2004); doi:10.1038/nm0204-127
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review article The STATs of cancer — new molecular targets come of age
Hua Yu and Richard Jove Nature Reviews Cancer4, 97–105
(February 2004); doi:10.1038/nrc1275
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letter Regulation of flowering time by FVE, a retinoblastoma-associated protein
Israel Ausín, Carlos Alonso-Blanco, José A Jarillo, Leonor Ruiz-García and José M Martínez-Zapater Nature Genetics36, 162–166
(February 2004); doi:10.1038/ng1295
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letter A genetic link between cold responses and flowering time through FVE in Arabidopsis thaliana
Hyoun-Joung Kim, Youbong Hyun, Jin-Young Park, Mi-Jin Park, Mi-Kyung Park, Myoung Duck Kim, Hye-Joung Kim, Mi Hyun Lee, Jihyun Moon, Ilha Lee and Jungmook Kim Nature Genetics36, 167–171
(February 2004); doi:10.1038/ng1298
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news and views Take a cold flower
Richard Amasino Nature Genetics36, 111–112
(February 2004); doi:10.1038/ng0204-111
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review article Network biology: understanding the cell's functional organization
Albert-László Barabási and Zoltán N. Oltvai Nature Reviews Genetics5, 101–113
(February 2004); doi:10.1038/nrg1272
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article Opiate state controls bi-directional reward signaling via GABAA receptors in the ventral tegmental area
Steven R Laviolette, Roger A Gallegos, Steven J Henriksen and Derek van der Kooy Nature Neuroscience7, 160–169
(February 2004); doi:10.1038/nn1182
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news and views Taking sides in the nervous system with miRNA
Piali Sengupta Nature Neuroscience7, 100–102
(February 2004); doi:10.1038/nn0204-100
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article Quantum dot ligands provide new insights into erbB/HER receptor-mediated signal transduction
Diane S Lidke, Peter Nagy, Rainer Heintzmann, Donna J Arndt-Jovin, Janine N Post, Hernan E Grecco, Elizabeth A Jares-Erijman and Thomas M Jovin Nature Biotechnology22, 198–203
(February 2004); doi:10.1038/nbt929
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news and views Enlightened receptor dynamics
Gal Gur and Yosef Yarden Nature Biotechnology22, 169–170
(February 2004); doi:10.1038/nbt0204-169
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article Crystal structure of MO25α in complex with the C terminus of the pseudo kinase STE20-related adaptor
Christine C Milburn, Jérôme Boudeau, Maria Deak, Dario R Alessi and Daan M F van Aalten Nature Structural and Molecular Biology11, 193–200
(February 2004); doi:10.1038/nsmb716
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news and views Barreling through the membrane
Arthur E Johnson and Robert E Jensen Nature Structural and Molecular Biology11, 113–114
(February 2004); doi:10.1038/nsmb0204-113
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review article cAMP detection methods in HTS: selecting the best from the rest
Christine Williams Nature Reviews Drug Discovery3, 125–135
(February 2004); doi:10.1038/nrd1306
| Abstract | Full Text (HTML / PDF) |
letters to nature Multiple transport modes of the cardiac Na+/Ca2+ exchanger
Tong Mook Kang and Donald W. Hilgemann Nature427, 544–548
(05 February 2004); doi:10.1038/nature02271
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letters to nature A proton pore in a potassium channel voltage sensor reveals a focused electric field
Dorine M. Starace and Francisco Bezanilla Nature427, 548–553
(05 February 2004); doi:10.1038/nature02270
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news and views Ion channels: Shake, rattle or roll?
Robert O. Blaustein and Christopher Miller Nature427, 553–558
(05 February 2004); doi:10.1038/nature02288
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letters to nature Dephosphorylated SRp38 acts as a splicing repressor in response to heat shock
Robert O. Blaustein and Christopher Miller Nature427, 499–500
(05 February 2004); doi:10.1038/427499a
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letters to nature Molecular engineering of a backwards-moving myosin motor
Georgios Tsiavaliaris, Setsuko Fujita-Becker and Dietmar J. Manstein Nature427, 558–561
(05 February 2004); doi:10.1038/nature02303
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article A physical and functional map of the human TNF-α/NF-kB signal transduction pathway
Tewis Bouwmeester, Angela Bauch, Heinz Ruffner, Pierre-Olivier Angrand, Giovanna Bergamini, Karen Croughton, Cristina Cruciat, Dirk Eberhard, Julien Gagneur, Sonja Ghidelli, Carsten Hopf, Bettina Huhse, Raffaella Mangano, Anne-Marie Michon, Markus Schirle, Judith Schlegl, Markus Schwab, Martin A. Stein, Andreas Bauer, Georg Casari, Gerard Drewes, Anne-Claude Gavin, David B. Jackson, Gerard Joberty, Gitte Neubauer, Jens Rick, Bernhard Kuster and Giulio Superti-Furga Nature Cell Biology6, 97–105
(February 2004); doi:10.1038/ncb1086
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news and views Keeping cartographers busy
Matthew S. Hayden and Sankar Ghosh Nature Cell Biology6, 87–89
(February 2004); doi:10.1038/ncb0204-87
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letter A novel mechanism for the store-operated calcium influx pathway
Tarik Smani, Sergey I. Zakharov, Peter Csutora, Endri Leno, Elena S. Trepakova and Victoria M. Bolotina Nature Cell Biology6, 113–120
(February 2004); doi:10.1038/ncb1089
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review article Plant cell biology: Traffic jams affect plant development and signal transduction
Marci Surpin and Natasha Raikhel Nature Reviews Molecular Cell Biology5, 100–109
(February 2004); doi:10.1038/nrm1311
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article TRADD interacts with STAT1-α and influences interferon-γ signaling
Duane R Wesemann, Hongwei Qin, Natalia Kokorina and Etty N Benveniste Nature Immunology5, 199–207
(February 2004); doi:10.1038/ni1025
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article N-domain-dependent nonphosphorylated STAT4 dimers required for cytokine-driven activation
Naruhisa Ota, Tom J Brett, Theresa L Murphy, Daved H Fremont and Kenneth M Murphy Nature Immunology5, 208–215
(February 2004); doi:10.1038/ni1032
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new and views Creating new peptide antigens by slicing and splicing proteins
Victor H Engelhard Nature Immunology5, 128–129
(February 2004); doi:10.1038/ni0204-128
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review article Role of the cytoskeleton during leukocyte responses
Miguel Vicente-Manzanares and Francisco Sánchez-Madrid Nature Reviews Immunology4, 110–122
(February 2004); doi:10.1038/nri1268
| Abstract | Full Text (HTML / PDF) |
letter The membrane-cytoskeleton linker ezrin is necessary for osteosarcoma metastasis
Chand Khanna, Xiaolin Wan, Seuli Bose, Ryan Cassaday, Osarenoma Olomu, Arnulfo Mendoza, Choh Yeung, Richard Gorlick, Stephen M Hewitt and Lee J Helman Nature Medicine10, 182–186
(February 2004); doi:10.1038/nm982
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brief communication Direct evidence that the VEGF-specific antibody bevacizumab has antivascular effects in human rectal cancer
Christopher G Willett, Yves Boucher, Emmanuelle di Tomaso, Dan G Duda, Lance L Munn, Ricky T Tong, Daniel C Chung, Dushyant V Sahani, Sanjeeva P Kalva, Sergey V Kozin, Mari Mino, Kenneth S Cohen, David T Scadden, Alan C Hartford, Alan J Fischman, Jeffrey W Clark, David P Ryan, Andrew X Zhu, Lawrence S Blaszkowsky, Helen X Chen, Paul C Shellito, Gregory Y Lauwers and Rakesh K Jain Nature Medicine10, 145–147
(February 2004); doi:10.1038/nm988
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news and views Inflamed about obesity
Michael Lehrke and Mitchell A Lazar Nature Medicine10, 126–127
(February 2004); doi:10.1038/nm0204-126
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review article Cell adhesion and signalling by cadherins and Ig-CAMs in cancer
Ugo Cavallaro and Gerhard Christofori Nature Reviews Cancer4, 118–132
(February 2004); doi:10.1038/nrc1276
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letter Dynamics of the p53-Mdm2 feedback loop in individual cells
Galit Lahav, Nitzan Rosenfeld, Alex Sigal, Naama Geva-Zatorsky, Arnold J Levine, Michael B Elowitz and Uri Alon Nature Genetics36, 147–150
(February 2004); doi:10.1038/ng1293
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news and views Monitoring p53's pulse
John J Tyson Nature Genetics36, 113–114
(February 2004); doi:10.1038/ng0204-113
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article Cypin regulates dendrite patterning in hippocampal neurons by promoting microtubule assembly
Barbara F Akum, Maxine Chen, Samuel I Gunderson, Gary M Riefler, Monica M Scerri-Hansen and Bonnie L Firestein Nature Neuroscience7, 145–152
(February 2004); doi:10.1038/nn1179
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perspective Myelin inhibitors: does NO mean GO?
Geoffrey Raisman Nature Reviews Neuroscience5, 157–161
(February 2004); doi:10.1038/nrn1328
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letter Intensity-based protein identification by machine learning from a library of tandem mass spectra
Joshua E Elias, Francis D Gibbons, Oliver D King, Frederick P Roth and Steven P Gygi Nature Biotechnology22, 214–219
(February 2004); doi:10.1038/nbt930
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letter FRET between cardiac Na+ channel subunits measured with a confocal microscope and a streak camera
Christoph Biskup, Thomas Zimmer and Klaus Benndorf Nature Biotechnology22, 220–224
(February 2004) ; doi:10.1038/nbt935
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review article Cytokine-receptor pairing: accelerating discovery of cytokine function
Don Foster, Julia Parrish-Novak, Brian Fox and Wenfeng Xu Nature Reviews Drug Discovery3, 160–170
(February 2004); doi:10.1038/nrd1305
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article Reactive oxygen species impair Slo1 BK channel function by altering cysteine-mediated calcium sensing
Xiang Dong Tang, Maria L Garcia, Stefan H Heinemann and Toshinori Hoshi Nature Structural and Molecular Biology11, 171–178
(February 2004); doi:10.1038/nsmb725
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news and views GTPase twins in the SRP family
Elisabet C Mandon and Reid Gilmore Nature Structural and Molecular Biology11, 115–116
(February 2004); doi:10.1038/nsmb0204-115
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