The Research Library categorizes, and provides access to, all recent signaling-related research published in the Nature Publishing Group journals. The selection is deliberately broad to facilitate access to all research impacting on the signaling community. Both primary research and review articles are included, as are 'News and Views' articles.
Click here for free access to the 'Featured Articles' section, with new articles every week.
article Nodal antagonists regulate formation of the anteroposterior axis of the mouse embryo
Masamichi Yamamoto, Yukio Saijoh, Aitana Perea-Gomez, William Shawlot, Richard R. Behringer, Siew-Lan Ang, Hiroshi Hamada and Chikara Meno Nature428, 387–392
(25 March 2004); doi:10.1038/nature02418
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letters to nature A resource for large-scale RNA-interference-based screens in mammals
Patrick J. Paddison, Jose M. Silva, Douglas S. Conklin , Mike Schlabach, Mamie Li, Shola Aruleba, Vivekanand Balija, Andy O'Shaughnessy, Lidia Gnoj, Kim Scobie, Kenneth Chang, Thomas Westbrook, Michele Cleary, Ravi Sachidanandam, W. Richard McCombie, Stephen J. Elledge and Gregory J. Hannon Nature428, 427–431
(25 March 2004); doi:10.1038/nature02370
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letters to nature A large-scale RNAi screen in human cells identifies new components of the p53 pathway
Katrien Berns, E. Marielle Hijmans, Jasper Mullenders, Thijn R. Brummelkamp, Arno Velds, Mike Heimerikx, Ron M. Kerkhoven, Mandy Madiredjo, Wouter Nijkamp, Britta Weigelt, Reuven Agami, Wei Ge, Guy Cavet, Peter S. Linsley, Roderick L. Beijersbergen and René Bernards Nature428, 431–437
(25 March 2004); doi:10.1038/nature02371
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news and views RNA interference: Human genes hit the big screen
Andrew Fraser Nature428, 375–378
(25 March 2004); doi:10.1038/428375a
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letters to nature Functional interactions between receptors in bacterial chemotaxis
Victor Sourjik and Howard C. Berg Nature428, 437–441
(25 March 2004); doi:10.1038/nature02406
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news and views Medicine: Profile of a tumour
Olli Kallioniemi Nature428, 379–382
(25 March 2004); doi:10.1038/428379b
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letter Correcting improper chromosome-spindle attachments during cell division
Michael A. Lampson, Kishore Renduchitala, Alexey Khodjakov and Tarun M. Kapoor Nature Cell Biology6, 232–237
(March 2004); doi:10.1038/ncb1102
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news and views Correcting SYNful attachments
Sue Biggins Nature Cell Biology6, 181–183
(March 2004); doi:10.1038/ncb0304-181
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letter Interactions of GGA3 with the ubiquitin sorting machinery
Rosa Puertollano and Juan S. Bonifacino Nature Cell Biology6, 244–251
(March 2004); doi:10.1038/ncb1106
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letter GGA proteins bind ubiquitin to facilitate sorting at the trans-Golgi network
Patricia M. Scott, Patricia S. Bilodeau, Olga Zhdankina, Stanley C. Winistorfer, Melissa J. Hauglund, Margaret M. Allaman, William R. Kearney, Andrew D. Robertson, Annette L. Boman and Robert C. Piper Nature Cell Biology6, 252–259
(March 2004); doi:10.1038/ncb1107
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news and views GGAing ubiquitin to the endosome
Markus Babst Nature Cell Biology6, 175–177
(March 2004); doi:10.1038/ncb0304-175
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letter Non-proteolytic inactivation of geminin requires CDK-dependent ubiquitination
Anatoliy Li and J. Julian Blow Nature Cell Biology6, 260–267
(March 2004); doi:10.1038/ncb1100
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news and views Translating prions at the synapse
Jonathan M. Levenson and J. David Sweatt Nature Cell Biology6, 184–187
(March 2004); doi:10.1038/ncb0304-184b
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news and views A SNAP decision in neural cell fate
Donald Mcdonald Nature Cell Biology6, 187
(March 2004); doi:10.1038/ncb0304-187
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review article Proteolysis within the membrane: rhomboids revealed
Matthew Freeman Nature Reviews Molecular Cell Biology5, 188–197
(March 2004); doi:10.1038/nrm1334
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review article Parsing the Polarity Code
Ian G. Macara Nature Reviews Molecular Cell Biology5, 220–231
(March 2004); doi:10.1038/nrm1332
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article Ternary complex factor SAP-1 is required for Erk-mediated thymocyte positive selection
Patrick S Costello, Robert H Nicolas, Yasuyuki Watanabe, Ian Rosewell and Richard Treisman Nature Immunology5, 289–298
(March 2004); doi:10.1038/ni1038
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article PRDI-BF1 recruits the histone H3 methyltransferase G9a in transcriptional silencing
Ildikó Gyõry, Jian Wu, György Fejér, Edward Seto and Kenneth L Wright Nature Immunology5, 299–308
(March 2004); doi:10.1038/ni1046
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news and views Sounds of a silent Blimp-1
Karen W Makar and Christopher B Wilson Nature Immunology5, 241–242
(March 2004); doi:10.1038/ni0304-241
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article B cell receptor signal strength determines B cell fate
Stefano Casola, Kevin L Otipoby, Marat Alimzhanov, Sibille Humme, Nathalie Uyttersprot, Jeffery L Kutok, Michael C Carroll and Klaus Rajewsky Nature Immunology5, 317–327
(March 2004); doi:10.1038/ni1036
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review article Notch regulation of lymphocyte development and function
Freddy Radtke, Anne Wilson, Stephane J C Mancini and H Robson MacDonald Nature Immunology5, 247–253
(March 2004); doi:10.1038/ni1045
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review article NOX enzymes and the biology of reactive oxygen
J. David Lambeth Nature Reviews Immunology4, 181–189
(March 2004); doi:10.1038/nri1312
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article Hepatic expression of malonyl-CoA decarboxylase reverses muscle, liver and whole-animal insulin resistance
Jie An, Deborah M Muoio, Masakazu Shiota, Yuka Fujimoto, Gary W Cline, Gerald I Shulman, Timothy R Koves, Robert Stevens, David Millington and Christopher B Newgard Nature Medicine10, 268–274
(March 2004); doi:10.1038/nm995
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letter AML-1 is required for megakaryocytic maturation and lymphocytic differentiation, but not for maintenance of hematopoietic stem cells in adult hematopoiesis
Motoshi Ichikawa, Takashi Asai, Toshiki Saito, Go Yamamoto, Sachiko Seo, Ieharu Yamazaki, Tetsuya Yamagata, Kinuko Mitani, Shigeru Chiba, Hisamaru Hirai, Seishi Ogawa and Mineo Kurokawa Nature Medicine10, 299–304
(March 2004); doi:10.1038/nm997
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news and views AML-1 steps up to the platelets
Brenda J Irvin and Scott W Hiebert Nature Medicine10, 238–239
(March 2004); doi:10.1038/nm0304-238
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letter A new cell-permeable peptide allows successful allogeneic islet transplantation in mice
Hirofumi Noguchi, Masayuki Matsushita, Teru Okitsu, Akiyoshi Moriwaki, Kazuhito Tomizawa, Sunghyun Kang, Sheng-Tian Li, Naoya Kobayashi, Shinichi Matsumoto, Koich Tanaka, Noriaki Tanaka and Hideki Matsui Nature Medicine10, 305–309
(March 2004); doi:10.1038/nm994
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news and views Nucleus hears axon's pain
Armin Blesch and Mark H Tuszynski Nature Medicine10, 236–237
(March 2004); doi:10.1038/nm0304-236
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news and views Laying down the bone
Charlotte Schubert Nature Medicine10, 237
(March 2004); doi:10.1038/nm0304-237
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review article A census of human cancer genes
P. Andrew Futreal, Lachlan Coin, Mhairi Marshall, Thomas Down, Timothy Hubbard, Richard Wooster, Nazneen Rahman and Michael R. Stratton Nature Reviews Cancer4, 177–183
(March 2004); doi:10.1038/nrc1299
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letter Gene expression-based high-throughput screening(GE-HTS) and application to leukemia differentiation
Kimberly Stegmaier, Kenneth N Ross, Sierra A Colavito, Shawn O'Malley, Brent R Stockwell and Todd R Golub Nature Genetics36, 257–263
(March 2004); doi:10.1038/ng1305
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news and views Gene expression as a drug discovery tool
William E Evans and R Kip Guy Nature Genetics36, 214–215
(March 2004); doi:10.1038/ng0304-214
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review article The evolution of genetic regulatory systems in bacteria
Harley H. McAdams, Balaji Srinivasan and Adam P. Arkin Nature Reviews Genetics5, 169–178
(March 2004); doi:10.1038/nrg1292
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article Creation of AMPA-silent synapses in the neonatal hippocampus
Min-Yi Xiao, Pontus Wasling, Eric Hanse and Bengt Gustafsson Nature Neuroscience7, 236–243
(March 2004); doi:10.1038/nn1196
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article Activity-dependent regulation of dendritic synthesis and trafficking of AMPA receptors
William Ju, Wade Morishita, Jennifer Tsui, Guido Gaietta, Thomas J Deerinck, Stephen R Adams, Craig C Garner, Roger Y Tsien, Mark H Ellisman and Robert C Malenka Nature Neuroscience7, 244–253
(March 2004); doi:10.1038/nn1189
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review article MAPK cascade signalling and synaptic plasticity
Gareth M. Thomas and Richard L. Huganir Nature Reviews Neuroscience5, 173–183
(March 2004); doi:10.1038/nrn1346
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research article Rational siRNA design for RNA interference
Angela Reynolds, Devin Leake, Queta Boese, Stephen Scaringe, William S Marshall and Anastasia Khvorova Nature Biotechnology22, 326–330
(March 2004); doi:10.1038/nbt936
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research article Antibody-targeted cell fusion
Takafumi Nakamura, Kah-Whye Peng, Sompong Vongpunsawad, Mary Harvey, Hiroyuki Mizuguchi, Takao Hayakawa, Roberto Cattaneo and Stephen J Russell Nature Biotechnology22, 331–336
(March 2004); doi:10.1038/nbt942
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letters to nature The candidate tumour suppressor protein ING4 regulates brain tumour growth and angiogenesis
Igor Garkavtsev, Sergey V. Kozin, Olga Chernova, Lei Xu, Frank Winkler, Edward Brown, Gene H. Barnett and Rakesh K. Jain Nature428, 328–332
(18 March 2004); doi:10.1038/nature02329
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letters to nature Survival signalling by Akt and eIF4E in oncogenesis and cancer therapy
Hans-Guido Wendel, Elisa de Stanchina, Jordan S. Fridman, Abba Malina, Sagarika Ray, Scott Kogan, Carlos Cordon-Cardo, Jerry Pelletier and Scott W. Lowe Nature428, 332–337
(18 March 2004); doi:10.1038/nature02369
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news and views Cancer: Survival pathways meet their end
Frank McCormick Nature428, 267–269
(18 March 2004); doi:10.1038/428267a
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letters to nature Bmi1 is essential for cerebellar development and is overexpressed in human medulloblastomas
Carly Leung, Merel Lingbeek, Olga Shakhova, James Liu, Ellen Tanger, Parvin Saremaslani, Maarten van Lohuizen and Silvia Marino Nature428, 337–341
(18 March 2004); doi:10.1038/nature02385
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letters to nature The protein kinase PKR is required for macrophage apoptosis after activation of Toll-like receptor 4
Li-Chung Hsu, Jin Mo Park, Kezhong Zhang, Jun-Li Luo, Shin Maeda, Randal J. Kaufman, Lars Eckmann, Donald G. Guiney and Michael Karin Nature428, 341–345
(18 March 2004); doi:10.1038/nature02405
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news and views Cancer: Dangerous liaisons
Allan Balmain and Rosemary J. Akhurst Nature428, 271–272
(18 March 2004); doi:10.1038/428271a
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article Polypyrimidine tract-binding protein promotes insulin secretory granule biogenesis
Klaus-Peter Knoch, Hendrik Bergert, Barbara Borgonovo, Hans-Detlev Saeger, Anke Altkrüger, Paul Verkade and Michele Solimena Nature Cell Biology6, 207–214
(March 2004); doi:10.1038/ncb1099
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letter Lipid raft proteins have a random distribution during localized activation of the T-cell receptor
Oleg O. Glebov and Benjamin J. Nichols Nature Cell Biology6, 238–243
(March 2004); doi:10.1038/ncb1103
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news and views To cluster or not to cluster: FRETting over rafts
Susan K. Pierce Nature Cell Biology6, 180–181
(March 2004); doi:10.1038/ncb0304-180
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review article Nucleocytoplasmic shuttling of signal transducers
Lan Xu and Joan Massagué Nature Reviews Molecular Cell Biology5, 209–219
(March 2004); doi:10.1038/nrm1331
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article Calcineurin imposes T cell unresponsiveness through targeted proteolysis of signaling proteins
Vigo Heissmeyer, Fernando Macián, Sin-Hyeog Im, Rajat Varma, Stefan Feske, K Venuprasad, Hua Gu, Yun-Cai Liu, Michael L Dustin and Anjana Rao Nature Immunology5, 255–265
(March 2004); doi:10.1038/ni1047
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news and views Behind the scenes of anergy: a tale of three E3s
Matti Davis and Yinon Ben-Neriah Nature Immunology5, 238–240
(March 2004); doi:10.1038/ni0304-238
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review article Immune surveillance in the skin: mechanisms and clinical consequences
Thomas S. Kupper and Robert C. Fuhlbrigge Nature Reviews Immunology4, 211–222
(March 2004); doi:10.1038/nri1310
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article VX-680, a potent and selective small-molecule inhibitor of the Aurora kinases, suppresses tumor growth in vivo
Elizabeth A Harrington, David Bebbington, Jeff Moore, Richele K Rasmussen, Abi O Ajose-Adeogun, Tomoko Nakayama, Joanne A Graham, Cecile Demur, Thierry Hercend, Anita Diu-Hercend, Michael Su, Julian M C Golec and Karen M Miller Nature Medicine10, 262–267
(March 2004); doi:10.1038/nm1003
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news and views Aurora kinases dawn as cancer drug targets
Edward A Sausville Nature Medicine10, 234–235
(March 2004); doi:10.1038/nm0304-234
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perspectives Opinion: Cancer as a robust system: implications for anticancer therapy
Hiroaki Kitano Nature Reviews Cancer4, 227–235
(March 2004); doi:10.1038/nrc1300
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letter The hyh mutation uncovers roles for αSnap in apical protein localization and control of neural cell fate
Teresa H Chae, Seonhee Kim, Karla E Marz, Phyllis I Hanson and Christopher A Walsh Nature Genetics36, 264–270
(March 2004); doi:10.1038/ng1302
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news and views Trafficking in cell fate
Sandra Bajjalieh Nature Genetics36, 216–217
(March 2004); doi:10.1038/ng0304-216
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brief communication Mutant P450 oxidoreductase causes disordered steroidogenesis with and without Antley-Bixler syndrome
Christa E Flück, Toshihro Tajima, Amit V Pandey, Wiebke Arlt, Kouji Okuhara, Charles F Verge, Ethylin Wang Jabs, Berenice B Mendonça, Kenji Fujieda and Walter L Miller Nature Genetics36, 228–230
(March 2004); doi:10.1038/ng1300
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review article Ontologies in biology: design, applications and future challenges
Jonathan B. L. Bard and Seung Y. Rhee Nature Reviews Genetics5, 213–222
(March 2004); doi:10.1038/nrg1295
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article LINGO-1 is a component of the Nogo-66 receptor/p75 signaling complex
Sha Mi, Xinhua Lee, Zhaohui Shao, Greg Thill, Benxiu Ji, Jane Relton, Melissa Levesque, Norm Allaire, Steve Perrin, Bryan Sands, Thomas Crowell, Richard L Cate, John M McCoy and R Blake Pepinsky Nature Neuroscience7, 221–228
(March 2004); doi:10.1038/nn1188
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review article Molecular mechanisms of taste-recognition memory
Federico Bermúdez-Rattoni Nature Reviews Neuroscience5, 209–217
(March 2004); doi:10.1038/nrn1344
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article Counterion displacement in the molecular evolution of the rhodopsin family
Akihisa Terakita, Mitsumasa Koyanagi, Hisao Tsukamoto, Takahiro Yamashita, Takashi Miyata and Yoshinori Shichida Nature Structural and Molecular Biology11, 284–289
(March 2004); doi:10.1038/nsmb731
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twenty questions The state of ion channel research in 2004
The Nature Reviews Drug Discovery Ion Channel Questionnaire Participants Nature Reviews Drug Discovery3, 239–278
(March 2004); doi:10.1038/nrd1361
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research article Interferon induction by siRNAs and ssRNAs synthesized by phage polymerase
Dong-Ho Kim, Michael Longo, Young Han, Patric Lundberg, Edouard Cantin and John J Rossi Nature Biotechnology22, 321–325
(March 2004); doi:10.1038/nbt940
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news and views Knockdown by RNAi—proceed with caution
Charles E Samuel Nature Biotechnology22, 280–282
(March 2004); doi:10.1038/nbt0304-280
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letters to nature Control of the SCFSkp2-Cks1 ubiquitin ligase by the APC/CCdh1 ubiquitin ligase
Tarig Bashir, N. Valerio Dorrello, Virginia Amador, Daniele Guardavaccaro and Michele Pagano Nature428, 190–193
(11 March 2004); doi:10.1038/nature02330
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letters to nature Degradation of the SCF component Skp2 in cell-cycle phase G1 by the anaphase-promoting complex
Wenyi Wei, Nagi G. Ayad, Yong Wan, Guo-Jun Zhang, Marc W. Kirschner and William G. Kaelin Jr Nature428, 194–198
(11 March 2004); doi:10.1038/nature02381
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letters to nature Insight into tubulin regulation from a complex with colchicine and a stathmin-like domain
Raimond B.G. Ravelli, Benoît Gigant, Patrick A. Curmi, Isabelle Jourdain, Sylvie Lachkar, André Sobel and Marcel Knossow Nature428, 198–202
(11 March 2004); doi:10.1038/nature02393
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article Minimal nuclear pore complexes define FG repeat domains essential for transport
Lisa A. Strawn, Tianxiang Shen, Nataliya Shulga, David S. Goldfarb and Susan R. Wente Nature Cell Biology6, 197–206
(March 2004); doi:10.1038/ncb1097
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news and views Robbing from the pore
Benjamin L. Timney and Michael P. Rout Nature Cell Biology6, 177–179
(March 2004); doi:10.1038/ncb0304-177
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review article Plant cell biology: Protein import into chloroplasts
Jürgen Soll and Enrico Schleiff Nature Reviews Molecular Cell Biology5, 198–208
(March 2004); doi:10.1038/nrm1333
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article Cis association of Ly49A with MHC class I restricts natural killer cell inhibition
Marie-Agnés Doucey, Léonardo Scarpellino, Jacques Zimmer, Philippe Guillaume, Immanuel F Luescher, Claude Bron and Werner Held Nature Immunology5, 328–336
(March 2004); doi:10.1038/ni1043
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news and views Having it both ways: MHC recognition in cis and trans
Paul J Leibson and Larry R Pease Nature Immunology5, 237–238
(March 2004); doi:10.1038/ni0304-237
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perspectives Opinion: Death-defying immunity: do apoptotic cells influence antigen processing and presentation?
Matthew L. Albert Nature Reviews Immunology4, 223–231
(March 2004); doi:10.1038/nri1308
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article PKC-α regulates cardiac contractility and propensity toward heart failure
Julian C Braz, Kimberly Gregory, Anand Pathak, Wen Zhao, Bogachan Sahin, Raisa Klevitsky, Thomas F Kimball, John N Lorenz, Angus C Nairn, Stephen B Liggett, Ilona Bodi, Su Wang, Arnold Schwartz, Edward G Lakatta, Anna A DePaoli-Roach, Jeffrey Robbins, Timothy E Hewett, James A Bibb, Margaret V Westfall, Evangelia G Kranias and Jeffery D Molkentin Nature Medicine10, 248–254
(March 2004); doi:10.1038/nm1000
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news and views Calcium handler mishandles heart
Hunter C Champion and David A Kass Nature Medicine10, 239–240
(March 2004); doi:10.1038/nm0304-239
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review article Targeting the checkpoint kinases: chemosensitization versus chemoprotection
Bin-Bing S. Zhou and Jiri Bartek Nature Reviews Cancer4, 216–225
(March 2004); doi:10.1038/nrc1296
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article The gene encoding 5-lipoxygenase activating protein confers risk of myocardial infarction and stroke
Anna Helgadottir, Andrei Manolescu, Gudmar Thorleifsson, Solveig Gretarsdottir, Helga Jonsdottir, Unnur Thorsteinsdottir, Nilesh J Samani, Gudmundur Gudmundsson, Struan F A Grant, Gudmundur Thorgeirsson, Sigurlaug Sveinbjornsdottir, Einar M Valdimarsson, Stefan E Matthiasson, Halldor Johannsson, Olof Gudmundsdottir, Mark E Gurney, Jesus Sainz, Margret Thorhallsdottir, Margret Andresdottir, Michael L Frigge, Eric J Topol, Augustine Kong, Vilmundur Gudnason, Hakon Hakonarson, Jeffrey R Gulcher & Kari Stefansson Nature Genetics36, 233–239
(March 2004); doi:10.1038/ng1311
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letter Indian Hedgehog is an antagonist of Wnt signaling in colonic epithelial cell differentiation
Gijs R van den Brink, Sylvia A Bleuming, James C H Hardwick, Berber L Schepman, G Johan Offerhaus, Josbert J Keller, Corinne Nielsen, William Gaffield, Sander J H van Deventer, Drucilla J Roberts & Maikel P Peppelenbosch Nature Genetics36, 277–282
(March 2004); doi:10.1038/ng1304
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perspectives Guidelines: Expression profiling — best practices for data generation and interpretation in clinical trials
The Tumor Analysis Best Practices Working Group Nature Reviews Genetics5, 229–237
(March 2004); doi:10.1038/nrg1297
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article In vivo imaging of synapse formation on a growing dendritic arbor
Cristopher M Niell, Martin P Meyer and Stephen J Smith Nature Neuroscience7, 254–260
(March 2004); doi:10.1038/nn1191
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news and views Single dendrite seeks stable relationship
Josh Morgan and Rachel Wong Nature Neuroscience7, 205–206
(March 2004); doi:10.1038/nn0304-205
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article Two distinct interaction motifs in amphiphysin bind two independent sites on the clathrin terminal domain β-propeller
Adriana E Miele, Peter J Watson, Philip R Evans, Linton M Traub and David J Owen Nature Structural and Molecular Biology11, 242–248
(March 2004); doi:10.1038/nsmb736
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news and views Turning on FLT3
Elizabeth Grzymski Nature Structural and Molecular Biology11, 212
(March 2004); doi:10.1038/nsmb0304-212
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review article Neurodegenerative diseases and oxidative stress
Kevin J. Barnham, Colin L. Masters and Ashley I. Bush Nature Reviews Drug Discovery3, 205–214
(March 2004); doi:10.1038/nrd1330
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research article Probing the precision of the mitotic clock with a live-cell fluorescent biosensor
Joshua T Jones, Jason W Myers, James E Ferrell and Jr Tobias Meyer Nature Biotechnology22, 306–312
(March 2004); doi:10.1038/nbt941
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news and views The pulse of mitosis
Conly L Rieder and Alexei Mikhailov Nature Biotechnology22, 279–280
(March 2004); doi:10.1038/nbt0304-279
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article Community structure and metabolism through reconstruction of microbial genomes from the environment
Gene W. Tyson, Jarrod Chapman, Philip Hugenholtz, Eric E. Allen, Rachna J. Ram, Paul M. Richardson, Victor V. Solovyev, Edward M. Rubin, Daniel S. Rokhsar and Jillian F. Banfield Nature428, 37–43
(04 March 2004); doi:10.1038/nature02340
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news and views Microbiology: Reconstructing the wild types
Edward F. Delong Nature428, 25–26
(04 March 2004); doi:10.1038/428025a
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letters to nature Inactivation of hCDC4 can cause chromosomal instability
Harith Rajagopalan, Prasad V. Jallepalli, Carlo Rago, Victor E. Velculescu, Kenneth W. Kinzler, Bert Vogelstein and Christoph Lengauer Nature428, 77–81
(04 March 2004); doi:10.1038/nature02313
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letters to nature Spatially restricted microRNA directs leaf polarity through ARGONAUTE1
Catherine A. Kidner and Robert A. Martienssen Nature428, 81–84
(04 March 2004); doi:10.1038/nature02366
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letters to nature microRNA-mediated repression of rolled leaf1 specifies maize leaf polarity
Michelle T. Juarez, Jonathan S. Kui, Julie Thomas, Bradley A. Heller and Marja C. P. Timmermans Nature428, 84–88
(04 March 2004); doi:10.1038/nature02363
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letters to nature A non-B-DNA structure at the Bcl-2 major breakpoint region is cleaved by the RAG complex
Sathees C. Raghavan, Patrick C. Swanson, Xiantuo Wu, Chih-Lin Hsieh and Michael R. Lieber Nature428, 88–93
(04 March 2004); doi:10.1038/nature02355
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news and views Molecular biology: Case of mistaken identity
Craig H. Bassing and Frederick W. Alt Nature428, 29–31
(04 March 2004); doi:10.1038/428029a
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news and views Cell biology: A cellular choreographer
W. James Nelson Nature428, 28–29
(04 March 2004); doi:10.1038/428028a
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article MKK7 couples stress signalling to G2/M cell-cycle progression and cellular senescence
Teiji Wada, Nicholas Joza, Hai-ying M. Cheng, Takehiko Sasaki, Ivona Kozieradzki, Kurt Bachmaier, Toshiaki Katada, Martin Schreiber, Erwin F. Wagner, Hiroshi Nishina and Josef M. Penninger Nature Cell Biology6, 215–226
(March 2004); doi:10.1038/ncb1098
| Abstract | Full Text (HTML/PDF) |
letter Abl-dependent tyrosine phosphorylation of Sos-1 mediates growth-factor-induced Rac activation
Patrizia Sini, Angela Cannas, Anthony J. Koleske, Pier Paolo Di Fiore and Giorgio Scita Nature Cell Biology6, 268–275
(March 2004); doi:10.1038/ncb1096
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review article Proteasomes and their kin: proteases in the machine age
Cecile M. Pickart and Robert E. Cohen Nature Reviews Molecular Cell Biology5, 177–187
(March 2004); doi:10.1038/nrm1336
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article ERM proteins regulate cytoskeleton relaxation promoting T cell-APC conjugation
Sophie Faure, Laura Inés Salazar-Fontana, Monique Semichon, Victor L J Tybulewicz, Georges Bismuth, Alain Trautmann, Ronald N Germain and Jérôme Delon Nature Immunology5, 272–279
(March 2004); doi:10.1038/ni1039
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article Duration of TCR signaling controls CD4-CD8 lineage differentiation in vivo
Xiaolong Liu and Rémy Bosselut Nature Immunology5, 280–288
(March 2004); doi:10.1038/ni1040
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review article Inhibitory NK-cell receptors on T cells: witness of the past, actors of the future
Eric Vivier and Nicolas Anfossi Nature Reviews Immunology4, 190–198
(March 2004); doi:10.1038/nri1306
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article Targeting angiogenesis with a conjugate of HPMA copolymer and TNP-470
Ronit Satchi-Fainaro, Mark Puder, John W Davies, Hai T Tran, David A Sampson, Arin K Greene, Gabriel Corfas and Judah Folkman Nature Medicine10, 255–261
(March 2004); doi:10.1038/nm1002
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brief communication Activation of nuclear hormone receptor peroxisome proliferator-activated receptor-d accelerates intestinal adenoma growth
Rajnish A Gupta, Dingzhi Wang, Sharada Katkuri, Haibin Wang, Sudhansu K Dey and Raymond N DuBois Nature Medicine10, 245–247
(March 2004); doi:10.1038/nm993
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news and views Fragile fugue: p53 in aging, cancer and IGF signaling
Judith Campisi Nature Medicine10, 231–232
(March 2004); doi:10.1038/nm0304-231
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review article Tumour-suppressor function in the nervous system
Suzanne J. Baker and Peter J. McKinnon Nature Reviews Cancer4, 184–196
(March 2004); doi:10.1038/nrc1297
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letter A complementary transposon tool kit for Drosophila melanogaster using P and piggyBac
Stephen T Thibault, Matthew A Singer, Wesley Y Miyazaki, Brett Milash, Nicholas A Dompe, Carol M Singh, Ross Buchholz, Madelyn Demsky, Robert Fawcett, Helen L Francis-Lang, Lisa Ryner, Lai Man Cheung, Angela Chong, Cathy Erickson, William W Fisher, Kimberly Greer, Stephanie R Hartouni, Elizabeth Howie, Lakshmi Jakkula, Daniel Joo, Keith Killpack, Alex Laufer, Julie Mazzotta, Ronald D Smith, Lynn M Stevens, Christiana Stuber, Lory R Tan, Richard Ventura, Alesa Woo, Irena Zakrajsek, Lora Zhao, Feng Chen, Candace Swimmer, Casey Kopczynski, Geoffrey Duyk, Margaret L Winberg and Jonathan Margolis Nature Genetics36, 283–287
(March 2004); doi:10.1038/ng1314
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letter Systematic generation of high-resolution deletion coverage of the Drosophila melanogaster genome
Annette L Parks, Kevin R Cook, Marcia Belvin, Nicholas A Dompe, Robert Fawcett, Kari Huppert, Lory R Tan, Christopher G Winter, Kevin P Bogart, Jennifer E Deal, Megan E Deal-Herr, Deanna Grant, Marie Marcinko, Wesley Y Miyazaki, Stephanie Robertson, Kenneth J Shaw, Mariano Tabios, Valentina Vysotskaia, Lora Zhao, Rachel S Andrade, Kyle A Edgar, Elizabeth Howie, Keith Killpack, Brett Milash, Amanda Norton, Doua Thao, Kellie Whittaker, Millicent A Winner, Lori Friedman, Jonathan Margolis, Matthew A Singer, Casey Kopczynski, Daniel Curtis, Thomas C Kaufman, Gregory D Plowman, Geoffrey Duyk and Helen L Francis-Lang Nature Genetics36, 288–292
(March 2004); doi:10.1038/ng1312
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news and views Flying in the face of total disruption
P Robin Hiesinger and Hugo J Bellen Nature Genetics36, 211–212
(March 2004); doi:10.1038/ng0304-211
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article FGF2-induced chromatin remodeling regulates CNTF-mediated gene expression and astrocyte differentiation
Mi-Ryoung Song and Anirvan Ghosh Nature Neuroscience7, 229–235
(March 2004); doi:10.1038/nn1192
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article PKC mediates inhibitory effects of myelin and chondroitin sulfate proteoglycans on axonal regeneration
Rajeev Sivasankaran, Jiong Pei, Kevin C Wang, Yi Ping Zhang, Christopher B Shields, Xiao-Ming Xu and Zhigang He Nature Neuroscience7, 261–268
(March 2004); doi:10.1038/nn1193
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review article Glycans and neural cell interactions
Ralf Kleene and Melitta Schachner Nature Reviews Neuroscience5, 195–208
(March 2004); doi:10.1038/nrn1349
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article An EF-hand in the sodium channel couples intracellular calcium to cardiac excitability
Tammy L Wingo, Vikas N Shah, Mark E Anderson, Terry P Lybrand, Walter J Chazin and Jeffrey R Balser Nature Structural and Molecular Biology11, 219–225
(March 2004); doi:10.1038/nsmb737
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