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The Research Library categorizes, and provides access to, all recent signaling-related research published in the Nature Publishing Group journals. The selection is deliberately broad to facilitate access to all research impacting on the signaling community. Both primary research and review articles are included, as are 'News and Views' articles.
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article
Crystal structure of the calcium pump with a bound ATP analogue
Chikashi Toyoshima and Tatsuaki Mizutani
Nature 430, 529–535
(29 July 2004); doi:10.1038/nature02680
| Abstract | Full Text (HTML / PDF) |
letters to nature
Median bundle neurons coordinate behaviours during Drosophila male courtship
Devanand S. Manoli and Bruce S. Baker
Nature 430, 564–569
(29 July 2004); doi:10.1038/nature02713
| First Paragraph | Full Text (HTML / PDF) |
letters to nature
Structural basis for vinculin activation at sites of cell adhesion
Constantina Bakolitsa, Daniel M. Cohen, Laurie A. Bankston, Andrey A. Bobkov, Gregory W. Cadwell, Lisa Jennings, David R. Critchley, Susan W. Craig and Robert C. Liddington
Nature 430, 583–586
(29 July 2004); doi:10.1038/nature02610
| First Paragraph | Full Text (HTML / PDF) |
news and views
Cell biology: How to build a cell junction
William I. Weis
Nature 430, 513–515
(29 July 2004); doi:10.1038/430513a
| Full Text (HTML / PDF) |
letters to nature
Low-populated folding intermediates of Fyn SH3 characterized by relaxation dispersion NMR
Dmitry M. Korzhnev , Xavier Salvatella, Michele Vendruscolo, Ariel A. Di Nardo, Alan R. Davidson, Christopher M. Dobson and Lewis E. Kay
Nature 430, 586–590
(29 July 2004); doi:10.1038/nature02655
| First Paragraph | Full Text (HTML / PDF) |
news and views
Neurobiology: Odorant receptors make scents
Rainer W. Friedrich
Nature 430, 511–512
(29 July 2004); doi:10.1038/430511a
| Full Text (HTML / PDF) |
letter
Proteolysis-independent regulation of the transcription factor Met4 by a single Lys 48-linked ubiquitin chain
Karin Flick, Ikram Ouni, James A. Wohlschlegel, Chrissy Capati, W. Hayes McDonald, John R. Yates 3rd and Peter Kaiser
Nature Cell Biology 6, 634–641
(July 2004); doi:10.1038/ncb1143
| First Paragraph | Full Text (HTML/PDF) |
news and views
Ubiquitin signalling: what's in a chain?
Mark Hochstrasser
Nature Cell Biology 6, 571–572
(July 2004); doi:10.1038/ncb0704-571
| Full Text (HTML/PDF) |
letter
HIF activation by pH-dependent nucleolar sequestration of VHL
Karim Mekhail, Lakshman Gunaratnam, Marie-Eve Bonicalzi and Stephen Lee
Nature Cell Biology 6, 642–647
(July 2004); doi:10.1038/ncb1144
| First Paragraph | Full Text (HTML/PDF) |
review article
Insights into morphogenesis from a simple developmental system
Rex L. Chisholm and Richard A. Firtel
Nature Reviews Molecular Cell Biology 5, 531–541
(July 2004); doi:10.1038/nrm1427
| Abstract | Full Text (HTML / PDF) |
article
Acute myeloid leukemia originates from a hierarchy of leukemic stem cell classes that differ in self-renewal capacity
Kristin J Hope, Liqing Jin and John E Dick
Nature Immunology 5, 738–743
(July 2004); doi:10.1038/ni1080
| Abstract | Full Text (HTML/PDF) |
news and views
Cancer stem cells refined
David T Scadden
Nature Immunology 5, 701–703
(July 2004); doi:10.1038/ni0704-701
| Full Text (HTML/PDF) |
review article
Post-proteasomal antigen processing for major histocompatibility complex class I presentation
Kenneth L Rock, Ian A York and Alfred L Goldberg
Nature Immunology 5, 670–677
(July 2004); doi:10.1038/ni1089
| Abstract | Full Text (HTML/PDF) |
review article
Neonatal adaptive immunity comes of age
Becky Adkins, Claude Leclerc and Stuart Marshall-Clarke
Nature Reviews Immunology 4, 553–564
(July 2004); doi:10.1038/nri1394
| Abstract | Full Text (HTML / PDF) |
article
Anti-obesity effects of α-lipoic acid mediated by suppression of hypothalamic AMP-activated protein kinase
Min-Seon Kim, Joong-Yeol Park, Cherl Namkoong, Pil-Geum Jang, Je-Won Ryu, Hai-Sun Song, Ji-Young Yun, Il-Seong Namgoong, Joohun Ha, In-Sun Park, In-Kyu Lee, Benoit Viollet, Jang Hyun Youn, Hong-Kyu Lee and Ki-Up Lee
Nature Medicine 10, 727–733
(July 2004); doi:10.1038/nm1061
| Abstract | Full Text (HTML/PDF) |
news and views
Cellular energy sensor balances the scales
Caroline J Small, David Carling and Stephen R Bloom
Nature Medicine 10, 681–682
(July 2004); doi:10.1038/nm0704-681
| Full Text (HTML/PDF) |
review article
Hyaluronan: from extracellular glue to pericellular cue
Bryan P. Toole
Nature Reviews Cancer 4, 528–539
(July 2004); doi:10.1038/nrc1391
| Abstract | Full Text (HTML / PDF) |
letter
A common polymorphism of the growth hormone receptor is associated with increased responsiveness to growth hormone
Christine Dos Santos, Laurent Essioux, Cécile Teinturier, Maïté Tauber, Vincent Goffin and Pierre Bougnères
Nature Genetics 36, 720–724
(July 2004); doi:10.1038/ng1379
| First Paragraph | Full Text (HTML/PDF) |
letter
BubR1 insufficiency causes early onset of aging-associated phenotypes and infertility in mice
Darren J Baker, Karthik B Jeganathan, J Douglas Cameron, Michael Thompson, Subhash Juneja, Alena Kopecka, Rajiv Kumar, Robert B Jenkins, Piet C de Groen, Patrick Roche and Jan M van Deursen
Nature Genetics 36, 744–749
(July 2004); doi:10.1038/ng1382
| First Paragraph | Full Text (HTML/PDF) |
news and views
Aging counts on chromosomes
Oscar Fernandez-Capetillo and André Nussenzweig
Nature Genetics 36, 672–674
(July 2004); doi:10.1038/ng0704-672
| Full Text (HTML/PDF) |
article
Calmodulin permanently associates with rat olfactory CNG channels under native conditions
Jonathan Bradley, Wolfgang Bönigk, King-Wai Yau and Stephan Frings
Nature Neuroscience 7, 705–710
(July 2004); doi:10.1038/nn1266
| Abstract | Full Text (HTML/PDF) |
news and views
Making scents of olfactory adaptation
John P Adelman and Paco S Herson
Nature Neuroscience 7, 689–690
(July 2004); doi:10.1038/nn0704-689
| Full Text (HTML/PDF) |
research article
An engineered epigenetic transgene switch in mammalian cells
Beat P Kramer, Alessandro Usseglio Viretta, Marie Daoud-El Baba, Dominique Aubel, Wilfried Weber and Martin Fussenegger
Nature Biotechnology 22, 867–870
(July 2004); doi:10.1038/nbt980
| First Paragraph | Full Text (HTML/PDF) |
research article
A tethered catalysis, two-hybrid system to identify protein-protein interactions requiring post-translational modifications
Dawei Guo, Tony R Hazbun, Xin-Jing Xu, Sze-Ling Ng, Stanley Fields and Min-Hao Kuo
Nature Biotechnology 22, 888–892
(July 2004); doi:10.1038/nbt985
| First Paragraph | Full Text (HTML/PDF) |
review article
A new modality for immunosuppression: targeting the JAK/STAT pathway
John J. O'Shea, Marko Pesu, Dominic C. Borie and Paul S. Changelian
Nature Reviews Drug Discovery 3, 555–564
(July 2004); doi:10.1038/nrd1441
| Abstract | Full Text (HTML / PDF) |
article
Structural basis for distinct ligand-binding and targeting properties of the receptors DC-SIGN and DC-SIGNR
Yuan Guo, Hadar Feinberg, Edward Conroy, Daniel A Mitchell, Richard Alvarez, Ola Blixt, Maureen E Taylor, William I Weis and Kurt Drickamer
Nature Structural and Molecular Biology 11, 591–598
(July 2004); doi:10.1038/nsmb784
| Abstract | Full Text (HTML/PDF) |
article
Ligand-induced rearrangement of the dimeric metabotropic glutamate receptor 1α
Michihiro Tateyama, Hideki Abe, Hiroyasu Nakata, Osamu Saito and Yoshihiro Kubo
Nature Structural and Molecular Biology 11, 637–642
(July 2004); doi:10.1038/nsmb770
| Abstract | Full Text (HTML/PDF) |
letters to nature
Drosophila long-term memory formation involves regulation of cathepsin activity
Daniel Comas, Florian Petit and Thomas Preat
Nature 430, 460–463
(22 July 2004); doi:10.1038/nature02726
| First Paragraph | Full Text (HTML / PDF) |
brief communication
Evolutionary genetics: Ambiguous role of CCR5 in Y. pestis infection
Stephen J. Elvin, E. Diane Williamson, Joanne C. Scott, Jeremy N. Smith, Guillermo Pérez de Lema, Silvia Chilla, Paul Clapham, Klaus Pfeffer, Detlef Schlöndorff and Bruno Luckow
Nature 430, 606–31
(22 July 2004); doi:10.1038/nature02822
| First Paragraph | Full Text (HTML / PDF) |
article
A NUDEL-dependent mechanism of neurofilament assembly regulates the integrity of CNS neurons
Minh Dang Nguyen, Tianzhi Shu, Kamon Sanada, Roxanne C. Larivière, Huang-Chun Tseng, Sang Ki Park, Jean-Pierre Julien and Li-Huei Tsai
Nature Cell Biology 6, 595–608
(July 2004); doi:10.1038/ncb1139
| Abstract | Full Text (HTML/PDF) |
news and views
Tangled NUDELs?
Erika L. F. Holzbaur
Nature Cell Biology 6, 569–570
(July 2004); doi:10.1038/ncb0704-569
| Full Text (HTML/PDF) |
letter
PML regulates p53 stability by sequestering Mdm2 to the nucleolus
Rosa Bernardi, Pier Paolo Scaglioni, Stephan Bergmann, Henning F. Horn, Karen H. Vousden and Pier Paolo Pandolfi
Nature Cell Biology 6, 665–672
(July 2004); doi:10.1038/ncb1147
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review article
Secretory trafficking in neuronal dendrites
April C. Horton and Michael D. Ehlers
Nature Cell Biology 6, 585–591
(July 2004); doi:10.1038/ncb0704-585
| Abstract | Full Text (HTML/PDF) |
review article
Plakins: Goliaths that link cell junctions and the cytoskeleton
Julius J. Jefferson, Conrad L. Leung and Ronald K. H. Liem
Nature Reviews Molecular Cell Biology 5, 542–553
(July 2004); doi:10.1038/nrm1425
| Abstract | Full Text (HTML / PDF) |
article
Localization of Rac2 via the C terminus and aspartic acid 150 specifies superoxide generation, actin polarity and chemotaxis in neutrophils
Marie-Dominique Filippi, Chad E Harris, Jarek Meller, Yi Gu, Yi Zheng and David A Williams
Nature Immunology 5, 744–751
(July 2004); doi:10.1038/ni1081
| Abstract | Full Text (HTML/PDF) |
article
Interleukin 31, a cytokine produced by activated T cells, induces dermatitis in mice
Stacey R Dillon, Cindy Sprecher, Angela Hammond, Janine Bilsborough, Maryland Rosenfeld-Franklin, Scott R Presnell, Harald S Haugen, Mark Maurer, Brandon Harder, Janet Johnston, Susan Bort, Sherri Mudri, Joseph L Kuijper, Tom Bukowski, Pamela Shea, Dennis L Dong, Maria Dasovich, Francis J Grant, Luann Lockwood, Steven D Levin, Cosette LeCiel, Kim Waggie, Heather Day, Stavros Topouzis, Janet Kramer, Rolf Kuestner, Zhi Chen, Don Foster, Julia Parrish-Novak and Jane A Gross
Nature Immunology 5, 752–760
(July 2004); doi:10.1038/ni1084
| Abstract | Full Text (HTML/PDF) |
review article
Cellular mechanisms governing cross-presentation of exogenous antigens
Anne L Ackerman and Peter Cresswell
Nature Immunology 5, 678–684
(July 2004); doi:10.1038/ni1082
| Abstract | Full Text (HTML/PDF) |
review article
The exogenous pathway for antigen presentation on major histocompatibility complex class II and CD1 molecules
Colin Watts
Nature Immunology 5, 685–692
(July 2004); doi:10.1038/ni1088
| Abstract | Full Text (HTML/PDF) |
perspectives
Landmark: The road to Toll
Bruno Lemaitre
Nature Reviews Immunology 4, 521–527
(July 2004); doi:10.1038/nri1390
| Abstract | Full Text (HTML / PDF) |
letter
Enhanced leptin sensitivity and attenuation of diet-induced obesity in mice with haploinsufficiency of Socs3
Jane K Howard, Belinda J Cave, Laura J Oksanen, Iphigenia Tzameli, Christian Bjørbæk and Jeffrey S Flier
Nature Medicine 10, 734–738
(July 2004); doi:10.1038/nm1072
| First Paragraph | Full Text (HTML/PDF) |
letter
Socs3 deficiency in the brain elevates leptin sensitivity and confers resistance to diet-induced obesity
Hiroyuki Mori, Reiko Hanada, Toshikatsu Hanada, Daisuke Aki, Ryuichi Mashima, Hitomi Nishinakamura, Takehiro Torisu, Kenneth R Chien, Hideo Yasukawa and Akihiko Yoshimura
Nature Medicine 10, 739–743
(July 2004); doi:10.1038/nm1071
| First Paragraph | Full Text (HTML/PDF) |
letter
Kaposi sarcoma herpesvirus-induced cellular reprogramming contributes to the lymphatic endothelial gene expression in Kaposi sarcoma
Hsei-Wei Wang, Matthew W B Trotter, Dimitrios Lagos, Dimitra Bourboulia, Stephen Henderson, Taija Mäkinen, Stephen Elliman, Adrienne M Flanagan, Kari Alitalo and Chris Boshoff
Nature Genetics 36, 687–693
(July 2004); doi:10.1038/ng1384
| First Paragraph | Full Text (HTML/PDF) |
brief communication
Lymphatic reprogramming of blood vascular endothelium by Kaposi sarcoma-associated herpesvirus
Young-Kwon Hong, Kimberly Foreman, Jay W Shin, Satoshi Hirakawa, Christine L Curry, David R Sage, Towia Libermann, Bruce J Dezube, Joyce D Fingeroth and Michael Detmar
Nature Genetics 36, 683–685
(July 2004); doi:10.1038/ng1383
| First Paragraph | Full Text (HTML/PDF) |
letter
Spatiotemporal regulation of endothelin receptor-B by SOX10 in neural crest-derived enteric neuron precursors
Lei Zhu, Hyung-Ok Lee, ChaRandle S Jordan, V Ashley Cantrell, E Michelle Southard-Smith and Myung K Shin
Nature Genetics 36, 732–737
(July 2004); doi:10.1038/ng1371
| First Paragraph | Full Text (HTML/PDF) |
review article
The cutting-edge of mammalian development; how the embryo makes teeth
Abigail Tucker and Paul Sharpe
Nature Reviews Genetics 5, 499–508
(July 2004); doi:10.1038/nrg1380
| Abstract | Full Text (HTML / PDF) |
brief communication
Inhibition of cyclooxygenase-2 potentiates retrograde endocannabinoid effects in hippocampus
Jimok Kim and Bradley E Alger
Nature Neuroscience 7, 697–698
(July 2004); doi:10.1038/nn1262
| First Paragraph | Full Text (HTML/PDF) |
review article
The neurobiology of antiepileptic drugs
Michael A. Rogawski and Wolfgang Löscher
Nature Reviews Neuroscience 5, 553–564
(July 2004); doi:10.1038/nrn1430
| Abstract | Full Text (HTML / PDF) |
research article
Temperature-sensitive control of protein activity by conditionally splicing inteins
Martin P Zeidler, Change Tan, Yohanns Bellaiche, Sara Cherry, Sabine Häder, Urte Gayko and Norbert Perrimon
Nature Biotechnology 22, 871–876
(July 2004); doi:10.1038/nbt979
| First Paragraph | Full Text (HTML/PDF) |
news and views
The ins and outs of gene expression control
Francine B Perler
Nature Biotechnology 22, 824–826
(July 2004); doi:10.1038/nbt0704-824
| Full Text (HTML/PDF) |
research article
A role for chemistry in stem cell biology
Sheng Ding and Peter G Schultz
Nature Biotechnology 22, 833–840
(July 2004); doi:10.1038/nbt987
| Abstract | Full Text (HTML/PDF) |
article
Distinct conformational states of nuclear receptor-bound CRSP-Med complexes
Dylan J Taatjes, Tilman Schneider-Poetsch and Robert Tjian
Nature Structural and Molecular Biology 11, 664–671
(July 2004); doi:10.1038/nsmb789
| Abstract | Full Text (HTML/PDF) |
article
GRK2 is an endogenous protein inhibitor of the insulin signaling pathway for glucose transport stimulation
Isao Usui, Takeshi Imamura, Hiroaki Satoh, Jie Huang, Jennie L Babendure, Christopher J Hupfeld and Jerrold M Olefsky
The EMBO Journal 23, 2821–2829
(July 2004); doi:10.1038/sj.emboj.7600297
| Abstract | Full Text (HTML/PDF) |
article
Oxygen sensation and social feeding mediated by a C. elegans guanylate cyclase homologue
Jesse M. Gray, David S. Karow, Hang Lu, Andy J. Chang, Jennifer S. Chang, Ronald E. Ellis, Michael A. Marletta and Cornelia I. Bargmann
Nature 430, 317–322
(15 July 2004); doi:10.1038/nature02714
| Abstract | Full Text (HTML / PDF) |
letters to nature
An SCF-like ubiquitin ligase complex that controls presynaptic differentiation
Edward H. Liao, Wesley Hung, Benjamin Abrams and Mei Zhen
Nature 430, 345–350
(15 July 2004); doi:10.1038/nature02647
| First Paragraph | Full Text (HTML / PDF) |
letters to nature
Cell fusion-independent differentiation of neural stem cells to the endothelial lineage
Andrew E. Wurmser, Kinichi Nakashima, Robert G. Summers, Nicolas Toni, Kevin A. D'Amour, Dieter C. Lie and Fred H. Gage
Nature 430, 350–356
(15 July 2004); doi:10.1038/nature02604
| First Paragraph | Full Text (HTML / PDF) |
letters to nature
The homeotic protein AGAMOUS controls microsporogenesis by regulation of SPOROCYTELESS
Toshiro Ito, Frank Wellmer, Hao Yu, Pradeep Das, Natsuko Ito, Márcio Alves-Ferreira, José Luis Riechmann and Elliot M. Meyerowitz
Nature 430, 356–360
(15 July 2004); doi:10.1038/nature02733
| First Paragraph | Full Text (HTML / PDF) |
letters to nature
Antero-posterior tissue polarity links mesoderm convergent extension to axial patterning
Hiromasa Ninomiya, Richard P. Elinson and Rudolf Winklbauer
Nature 430, 364–367
(15 July 2004); doi:10.1038/nature02620
| First Paragraph | Full Text (HTML / PDF) |
news and views
Developmental biology: Heading away from the rump
Ray Keller
Nature 430, 305–306
(15 July 2004); doi:10.1038/430305a
| Full Text (HTML / PDF) |
news and views
Plant biology: Good neighbours
Laura Serna
Nature 430, 302–304
(15 July 2004); doi:10.1038/430302a
| Full Text (HTML / PDF) |
letter
ATR and ATM regulate the timing of DNA replication origin firing
David Shechter, Vincenzo Costanzo and Jean Gautier
Nature Cell Biology 6, 648–655
(July 2004); doi:10.1038/ncb1145
| First Paragraph | Full Text (HTML/PDF) |
news and views
Sleeping policemen for DNA replication?
Daniel Fisher and Marcel Méchali
Nature Cell Biology 6, 576–577
(July 2004); doi:10.1038/ncb0704-576
| Full Text (HTML/PDF) |
review article
Calcium, kinases and nodulation signalling in legumes
Giles E. D. Oldroyd and J. Allan Downie
Nature Reviews Molecular Cell Biology 5, 566–576
(July 2004); doi:10.1038/nrm1424
| Abstract | Full Text (HTML / PDF) |
article
Critical functions for c-Myb at three checkpoints during thymocyte development
Timothy P Bender, Christopher S Kremer, Manfred Kraus, Thorsten Buch and Klaus Rajewsky
Nature Immunology 5, 721–729
(July 2004); doi:10.1038/ni1085
| Abstract | Full Text (HTML/PDF) |
review article
Generation of major histocompatibility complex class I antigens: functional interplay between proteasomes and TPPII
Peter M Kloetzel
Nature Immunology 5, 661–669
(July 2004); doi:10.1038/ni1090
| Abstract | Full Text (HTML/PDF) |
review article
Toll-like receptor signalling
Shizuo Akira and Kiyoshi Takeda
Nature Reviews Immunology 4, 499–511
(July 2004); doi:10.1038/nri1391
| Abstract | Full Text (HTML / PDF) |
article
Initiation of neuropathic pain requires lysophosphatidic acid receptor signaling
Makoto Inoue, Md Harunor Rashid, Ryousuke Fujita, James J A Contos, Jerold Chun and Hiroshi Ueda
Nature Medicine 10, 712–718
(July 2004); doi:10.1038/nm1060
| Abstract | Full Text (HTML/PDF) |
news and views
APCs size up antigens
Keith S Bahjat and Stephen P Schoenberger
Nature Medicine 10, 679–681
(July 2004); doi:10.1038/nm0704-679
| Full Text (HTML/PDF) |
review article
Insulin-like growth factors and neoplasia
Michael N. Pollak, Eva S. Schernhammer and Susan E. Hankinson
Nature Reviews Cancer 4, 505–518
(July 2004); doi:10.1038/nrc1387
| Abstract | Full Text (HTML / PDF) |
letter
p38 pathway targets SWI-SNF chromatin-remodeling complex to muscle-specific loci
Cristiano Simone, Sonia Vanina Forcales, David A Hill, Anthony N Imbalzano, Lucia Latella and Pier Lorenzo Puri
Nature Genetics 36, 738–743
(July 2004); doi:10.1038/ng1378
| First Paragraph | Full Text (HTML/PDF) |
news and views
Something to SNF about
Mark A Gillespie and Michael A Rudnicki
Nature Genetics 36, 676–677
(July 2004); doi:10.1038/ng0704-676
| Full Text (HTML/PDF) |
article
Dopamine depletion impairs precursor cell proliferation in Parkinson disease
Günter U Höglinger, Pamela Rizk, Marie P Muriel, Charles Duyckaerts, Wolfgang H Oertel, Isabelle Caille and Etienne C Hirsch
Nature Neuroscience 7, 726–735
(July 2004); doi:10.1038/nn1265
| Abstract | Full Text (HTML/PDF) |
review article
State-dependent opioid control of pain
Howard Fields
Nature Reviews Neuroscience 5, 565–575
(July 2004); doi:10.1038/nrn1431
| Abstract | Full Text (HTML / PDF) |
research article
Nanoliter-scale synthesis of arrayed biomaterials and application to human embryonic stem cells
Daniel G Anderson, Shulamit Levenberg and Robert Langer
Nature Biotechnology 22, 863–866
(July 2004); doi:10.1038/nbt981
| First Paragraph | Full Text (HTML/PDF) |
news and views
Biomaterials science and high-throughput screening
Jeffrey A Hubbell
Nature Biotechnology 22, 828–829
(July 2004); doi:10.1038/nbt0704-828
| Full Text (HTML/PDF) |
review article
Novel therapeutic approaches for heart failure by normalizing calcium cycling
Xander H. T. Wehrens and Andrew R. Marks
Nature Reviews Drug Discovery 3, 565–574
(July 2004); doi:10.1038/nrd1440
| Abstract | Full Text (HTML / PDF) |
article
TFIIH contains a PH domain involved in DNA nucleotide excision repair
Virginie Gervais, Valérie Lamour, Anass Jawhari, Florent Frindel, Emeric Wasielewski, Sandy Dubaele, Jean-Marc Egly, Jean-Claude Thierry, Bruno Kieffer and Arnaud Poterszman
Nature Structural and Molecular Biology 11, 616–622
(July 2004); doi:10.1038/nsmb782
| Abstract | Full Text (HTML/PDF) |
news and views
Transcription meets DNA repair at a PH domain
Kon Yew Kwek, William O'Gorman and Alexandre Akoulitchev
Nature Structural and Molecular Biology 11, 588–589
(July 2004); doi:10.1038/nsmb0704-588
| Full Text (HTML/PDF) |
article
Somatic diversification of variable lymphocyte receptors in the agnathan sea lamprey
Zeev Pancer, Chris T. Amemiya, Götz R. A. Ehrhardt, Jill Ceitlin, G. Larry Gartland and Max D. Cooper
Nature 430, 174–180
(08 July 2004); doi:10.1038/nature02740
| Abstract | Full Text (HTML / PDF) |
news and views
Immunology: Another manifestation of GOD
Martin F. Flajnik
Nature 430, 157–158
(08 July 2004); doi:10.1038/430157a
| Full Text (HTML / PDF) |
letters to nature
Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf
Sanjeev Mariathasan, Kim Newton, Denise M. Monack, Domagoj Vucic, Dorothy M. French, Wyne P. Lee, Meron Roose-Girma, Sharon Erickson and Vishva M. Dixit
Nature 430, 213–218
(08 July 2004); doi:10.1038/nature02664
| First Paragraph | Full Text (HTML / PDF) |
letters to nature
Regulation of Toll/IL-1-receptor-mediated gene expression by the inducible nuclear protein IkBζ
Masahiro Yamamoto, Soh Yamazaki, Satoshi Uematsu, Shintaro Sato, Hiroaki Hemmi, Katsuaki Hoshino, Tsuneyasu Kaisho, Hirotaka Kuwata, Osamu Takeuchi, Koichiro Takeshige, Tatsuya Saitoh, Shoji Yamaoka, Naoki Yamamoto, Shunsuke Yamamoto, Tatsushi Muta, Kiyoshi Takeda and Shizuo Akira
Nature 430, 218–222
(08 July 2004); doi:10.1038/nature02738
| First Paragraph | Full Text (HTML / PDF) |
letters to nature
Cyclin-dependent kinases regulate the antiproliferative function of Smads
Isao Matsuura , Natalia G. Denissova , Guannan Wang , Dongming He , Jianyin Long and Fang Liu
Nature 430, 226–231
(08 July 2004); doi:10.1038/nature02650
| First Paragraph | Full Text (HTML / PDF) |
letters to nature
A membrane-access mechanism of ion channel inhibition by voltage sensor toxins from spider venom
Seok-Yong Lee and Roderick MacKinnon
Nature 430, 232–235
(08 July 2004); doi:10.1038/nature02632
| First Paragraph | Full Text (HTML / PDF) |
letters to nature
Bilayer-dependent inhibition of mechanosensitive channels by neuroactive peptide enantiomers
Thomas M. Suchyna, Sonya E. Tape, Roger E. Koeppe II, Olaf S. Andersen, Frederick Sachs and Philip A. Gottlieb
Nature 430, 235–240
(08 July 2004); doi:10.1038/nature02743
| First Paragraph | Full Text (HTML / PDF) |
news and views
Ion channels: Gate expectations
Maria L. Garcia
Nature 430, 153–155
(08 July 2004); doi:10.1038/430153a
| Full Text (HTML / PDF) |
news and views
Immunology: Polarizing a T-cell response
Sophie M. Lehar and Michael J. Bevan
Nature 430, 150–151
(08 July 2004); doi:10.1038/430150a
| Full Text (HTML / PDF) |
news and views feature
The RNAi revolution
Carl D. Novina and Phillip A. Sharp
Nature 430, 161–164
(08 July 2004); doi:10.1038/430161a
| Full Text (HTML / PDF) |
review
Frontal and stealth attack strategies in microbial pathogenesis
D. Scott Merrell and Stanley Falkow
Nature 430, 250–256
(08 July 2004); doi:10.1038/nature02760
| Abstract | Full Text (HTML / PDF) |
review
Inferences, questions and possibilities in Toll-like receptor signalling
Bruce Beutler
Nature 430, 257–263
(08 July 2004); doi:10.1038/nature02761
| Abstract | Full Text (HTML / PDF) |
review
Translating cell biology in vitro to immunity in vivo
Marianne Boes and Hidde L. Ploegh
Nature 430, 264–271
(08 July 2004); doi:10.1038/nature02762
| Abstract | Full Text (HTML / PDF) |
letter
Phosphorylation of the enteropathogenic E. coli receptor by the Src-family kinase c-Fyn triggers actin pedestal formation
Neil Phillips, Richard D. Hayward and Vassilis Koronakis
Nature Cell Biology 6, 618–625
(July 2004); doi:10.1038/ncb1148
| First Paragraph | Full Text (HTML/PDF) |
letter
Pygopus and Legless target Armadillo/β-catenin to the nucleus to enable its transcriptional co-activator function
Fiona M. Townsley, Adam Cliffe and Mariann Bienz
Nature Cell Biology 6, 626–633
(July 2004); doi:10.1038/ncb1141
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A nuclear escort for β-catenin
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Nature Cell Biology 6, 579–580
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Mitochondrial import and the twin-pore translocase
Peter Rehling, Katrin Brandner and Nikolaus Pfanner
Nature Reviews Molecular Cell Biology 5, 519–530
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The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses
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Nature Immunology 5, 730–737
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RIGging an antiviral defense—it's in the CARDs
David E Levy and Isabelle J Marié
Nature Immunology 5, 699–701
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Therapeutics targeting the innate immune system
Richard J. Ulevitch
Nature Reviews Immunology 4, 512–520
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Cannabinoids cool the intestine
George Kunos and Pál Pacher
Nature Medicine 10, 678–679
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Jagruti H. Patel, Andrey P. Loboda, Michael K. Showe, Louise C. Showe and Steven B. McMahon
Nature Reviews Cancer 4, 562–568
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Instability of Hes7 protein is crucial for the somite segmentation clock
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Nature Genetics 36, 750–754
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One tissue, two fates: molecular genetic events that underlie testis versus ovary development
Jennifer Brennan and Blanche Capel
Nature Reviews Genetics 5, 509–521
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The neurite outgrowth inhibitor Nogo A is involved in autoimmune-mediated demyelination
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Nature Neuroscience 7, 736–744
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Laurent Groc, Martin Heine, Laurent Cognet, Kieran Brickley, F Anne Stephenson, Brahim Lounis and Daniel Choquet
Nature Neuroscience 7, 695–696
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Nature Biotechnology 22, 841–847
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Custom design of metabolism
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Nature Biotechnology 22, 823–824
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Nature Reviews Drug Discovery 3, 577–626
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Cancer: Understanding the target
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Evolutionary genomics: Seeing double
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Evidence for dynamically organized modularity in the yeast protein–protein interaction network
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Nature 430, 88–93
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PTK7/CCK-4 is a novel regulator of planar cell polarity in vertebrates
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Context-dependent contributions of backbone hydrogen bonding to -sheet folding energetics
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LATS1 tumour suppressor affects cytokinesis by inhibiting LIMK1
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Nature Cell Biology 6, 609–617
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Centriolar SAS-5 is required for centrosome duplication in C. elegans
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Uncoiling centriole duplication
Bruce Nash and Bruce Bowerman
Nature Cell Biology 6, 573–575
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The cell biology of lysosomal storage disorders
Anthony H. Futerman and Gerrit van Meer
Nature Reviews Molecular Cell Biology 5, 554–565
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Sphingosine 1-phosphate receptor 1 promotes B cell localization in the splenic marginal zone
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Nature Immunology 5, 713–720
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Should we B-leavin' now?
Michael D Gunn and Garnett Kelsoe
Nature Immunology 5, 703–704
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CD4/CD8-lineage differentiation in the thymus: from nuclear effectors to membrane signals
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Nature Reviews Immunology 4, 529–540
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Apolipoprotein E promotes astrocyte colocalization and degradation of deposited amyloid- peptides
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Nature Medicine 10, 719–726
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LARGE can functionally bypass -dystroglycan glycosylation defects in distinct congenital muscular dystrophies
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Nature Medicine 10, 696–703
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Glycosylation eases muscular dystrophy
Francesco Muntoni, Martin Brockington and Susan C Brown
Nature Medicine 10, 676–677
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Cancer and the chemokine network
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Nature Reviews Cancer 4, 540–550
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Identification of TFB5, a new component of general transcription and DNA repair factor IIH
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Nature Genetics 36, 707–713
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A new, tenth subunit of TFIIH is responsible for the DNA repair syndrome trichothiodystrophy group A
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From proteomics to disease
Kenneth H Kraemer
Nature Genetics 36, 677–678
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Laurent Groc, Martin Heine, Laurent Cognet, Kieran Brickley, F Anne Stephenson, Brahim Lounis and Daniel Choquet
Nature Neuroscience 7, 695–696
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Nature Neuroscience 7, 711–718
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A mechanism for homeostatic plasticity
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Nature Neuroscience 7, 691–692
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Immune signalling in neural development, synaptic plasticity and disease
Lisa M. Boulanger and Carla J. Shatz
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Cold-shock induced high-yield protein production in Escherichia coli
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Nature Biotechnology 22, 877–882
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A cool way to make proteins
Catherine H Schein
Nature Biotechnology 22, 826–827
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