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The Research Library categorizes, and provides access to, all recent signaling-related research published in the Nature Publishing Group journals. The selection is deliberately broad to facilitate access to all research impacting on the signaling community. Both primary research and review articles are included, as are 'News and Views' articles.
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letters to nature
Control of phyllotaxy by the cytokinin-inducible response regulator homologue ABPHYL1
Anna Giulini, Jing Wang and David Jackson
Nature 430, 1031–1034
(26 August 2004); doi:10.1038/nature02778
| First Paragraph | Full Text (HTML / PDF) |
letters to nature
Suppression of anoikis and induction of metastasis by the neurotrophic receptor TrkB
Sirith Douma, Theo van Laar, John Zevenhoven, Ralph Meuwissen, Evert van Garderen and Daniel S. Peeper
Nature 430, 1034–1039
(26 August 2004); doi:10.1038/nature02765
| First Paragraph | Full Text (HTML / PDF) |
news and views
Anoikis: Cancer and the homeless cell
Lance A. Liotta and Elise Kohn
Nature 430, 973–974
(26 August 2004); doi:10.1038/430973a
| Full Text (HTML / PDF) |
letters to nature
Argos inhibits epidermal growth factor receptor signalling by ligand sequestration
Daryl E. Klein, Valerie M. Nappi, Gregory T. Reeves, Stanislav Y. Shvartsman and Mark A. Lemmon
Nature 430, 1040–1044
(26 August 2004); doi:10.1038/nature02840
| First Paragraph | Full Text (HTML / PDF) |
letters to nature
Separase-mediated cleavage of cohesin at interphase is required for DNA repair
Koji Nagao, Yoh Adachi and Mitsuhiro Yanagida
Nature 430, 1044–1048
(26 August 2004); doi:10.1038/nature02803
| First Paragraph | Full Text (HTML / PDF) |
letters to nature
Structural basis for glycosphingolipid transfer specificity
Lucy Malinina, Margarita L. Malakhova, Alexei Teplov, Rhoderick E. Brown and Dinshaw J. Patel
Nature 430, 1048–1053
(26 August 2004); doi:10.1038/nature02856
| First Paragraph | Full Text (HTML / PDF) |
news and views
Chemical biology: Green fluorescent RNA
Michael Famulok
Nature 430, 976–977
(26 August 2004); doi:10.1038/430976a
| Full Text (HTML / PDF) |
letter
The mammalian retromer regulates transcytosis of the polymeric immunoglobulin receptor
Marcel Vergés, Frédéric Luton, Carmen Gruber, Frank Tiemann, Lorri G. Reinders, Lan Huang, Alma L. Burlingame, Carol R. Haft and Keith E. Mostov
Nature Cell Biology 6, 763–769
(August 2004); doi:10.1038/ncb1153
| First Paragraph | Full Text (HTML/PDF) |
letter
MLK3 is required for mitogen activation of B-Raf, ERK and cell proliferation
Deborah N. Chadee and John M. Kyriakis
Nature Cell Biology 6, 770–776
(August 2004); doi:10.1038/ncb1152
| First Paragraph | Full Text (HTML/PDF) |
review article
Cytoplasmic intermediate filaments revealed as dynamic and multipurpose scaffolds
Pierre A. Coulombe and Pauline Wong
Nature Cell Biology 6, 699–706
(August 2004); doi:10.1038/ncb0804-699
| Abstract | Full Text (HTML/PDF) |
news and views
Closing in on vertebrate planar polarity
John B. Wallingford
Nature Cell Biology 6, 687–689
(August 2004); doi:10.1038/ncb0804-687
| Full Text (HTML/PDF) |
review article
Foot and mouth: podosomes, invadopodia and circular dorsal ruffles
Roberto Buccione, James D. Orth and Mark A. McNiven
Nature Reviews Molecular Cell Biology 5, 647–657
(August 2004); doi:10.1038/nrm1436
| Summary | Full Text (HTML / PDF) |
review article
Cytoskeletal regulation: rich in lipids
Paul A. Janmey and Uno Lindberg
Nature Reviews Molecular Cell Biology 5, 658–666
(August 2004); doi:10.1038/nrm1434
| Summary | Full Text (HTML / PDF) |
article
T cells express a phagocyte-type NADPH oxidase that is activated after T cell receptor stimulation
Sharon H Jackson, Satish Devadas, Jaeyul Kwon, Ligia A Pinto and Mark S Williams
Nature Immunology 5, 818–827
(August 2004); doi:10.1038/ni1096
| Abstract | Full Text (HTML/PDF) |
article
B cell-specific loss of histone 3 lysine 9 methylation in the VH locus depends on Pax5
Kristen Johnson, David L Pflugh, Duonan Yu, David G T Hesslein, Kuo-I Lin, Alfred L M Bothwell, Andrei Thomas-Tikhonenko, David G Schatz and Kathryn Calame
Nature Immunology 5, 853–861
(August 2004); doi:10.1038/ni1099
| Abstract | Full Text (HTML/PDF) |
review article
Protein kinase C and beyond
Martin Spitaler and Doreen A Cantrell
Nature Immunology 5, 785–790
(August 2004); doi:10.1038/ni1097
| Abstract | Full Text (HTML/PDF) |
review article
Transmembrane adaptor proteins: organizers of immunoreceptor signalling
Václav Horejší, Weiguo Zhang and Burkhart Schraven
Nature Reviews Immunology 4, 603–616
(August 2004); doi:10.1038/nri1414
| Summary | Full Text (HTML / PDF) |
perspectives
Innovation: Seventeen-colour flow cytometry: unravelling the immune system
Stephen P. Perfetto, Pratip K. Chattopadhyay and Mario Roederer
Nature Reviews Immunology 4, 648–655
(August 2004); doi:10.1038/nri1416
| Summary | Full Text (HTML / PDF) |
article
P2X7 receptor inhibition improves recovery after spinal cord injury
Xiaohai Wang, Gregory Arcuino, Takahiro Takano, Jane Lin, Wei Guo Peng, Pinglan Wan, Pingjia Li, Qiwu Xu, Qing Song Liu, Steven A Goldman and Maiken Nedergaard
Nature Medicine 10, 821–827
(August 2004); doi:10.1038/nm1082
| Abstract | Full Text (HTML/PDF) |
news and views
Tracking down huntingtin
Juan Carlos López
Nature Medicine 10, 776
(August 2004); doi:10.1038/nm0804-776
| Full Text (HTML/PDF) |
review article
Biologically active sphingolipids in cancer pathogenesis and treatment
Besim Ogretmen and Yusuf A. Hannun
Nature Reviews Cancer 4, 604–616
(August 2004); doi:10.1038/nrc1411
| Summary | Full Text (HTML / PDF) |
article
VEGF links hippocampal activity with neurogenesis, learning and memory
Lei Cao, Xiangyang Jiao, David S Zuzga, Yuhong Liu, Dahna M Fong, Deborah Young and Matthew J During
Nature Genetics 36, 827–835
(August 2004); doi:10.1038/ng1395
| Abstract | Full Text (HTML/PDF) |
news and views
Experiencing VEGF
David A Greenberg and Kunlin Jin
Nature Genetics 36, 792–793
(August 2004); doi:10.1038/ng0804-792
| Full Text (HTML/PDF) |
letter
A functional variant of SUMO4, a new IkBa modifier, is associated with type 1 diabetes
Dehuang Guo, Manyu Li, Yan Zhang, Ping Yang, Sarah Eckenrode, Diane Hopkins, Weipeng Zheng, Sharad Purohit, Robert H Podolsky, Andrew Muir, Jinzhao Wang, Zheng Dong, Todd Brusko, Mark Atkinson, Paolo Pozzilli, Adina Zeidler, Leslie J Raffel, Chaim O Jacob, Yongsoo Park, Manuel Serrano-Rios, Maria T Martinez Larrad, Zixin Zhang, Henri-Jean Garchon, Jean-Francois Bach, Jerome I Rotter, Jin-Xiong She and Cong-Yi Wang
Nature Genetics 36, 837–841
(August 2004); doi:10.1038/ng1391
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letter
Caenorhabditis elegans ABL-1 antagonizes p53-mediated germline apoptosis after ionizing irradiation
Xinzhu Deng, E Randal Hofmann, Alberto Villanueva, Oliver Hobert, Paola Capodieci, Darren R Veach, Xianglei Yin, Luis Campodonico, Athanasios Glekas, Carlos Cordon-Cardo, Bayard Clarkson, William G Bornmann, Zvi Fuks, Michael O Hengartner and Richard Kolesnick
Nature Genetics 36, 906–912
(August 2004); doi:10.1038/ng1396
| First Paragraph | Full Text (HTML/PDF) |
article
The type 1 equilibrative nucleoside transporter regulates ethanol intoxication and preference
Doo-Sup Choi, Maria-Grazia Cascini, William Mailliard, Hannah Young, Peter Paredes, Thomas McMahon, Ivan Diamond, Antonello Bonci and Robert O Messing
Nature Neuroscience 7, 855–861
(August 2004); doi:10.1038/nn1288
| Abstract | Full Text (HTML/PDF) |
news and views
Last call for adenosine transporters
Roberto I Melendez and Peter W Kalivas
Nature Neuroscience 7, 795–796
(August 2004); doi:10.1038/nn0804-795
| Full Text (HTML/PDF) |
research article
In vivo cancer targeting and imaging with semiconductor quantum dots
Xiaohu Gao, Yuanyuan Cui, Richard M Levenson, Leland W K Chung and Shuming Nie
Nature Biotechnology 22, 969–976
(August 2004); doi:10.1038/nbt994
| Abstract | Full Text (HTML/PDF) |
news and views
Zooming in and out with quantum dots
Rakesh K Jain and Mark Stroh
Nature Biotechnology 22, 959–960
(August 2004); doi:10.1038/nbt0804-959
| Full Text (HTML/PDF) |
research article
Caged phosphopeptides reveal a temporal role for 14-3-3 in G1 arrest and S-phase checkpoint function
Anhco Nguyen, Deborah M Rothman, Justine Stehn, Barbara Imperiali and Michael B Yaffe
Nature Biotechnology 22, 993–1000
(August 2004); doi:10.1038/nbt997
| Abstract | Full Text (HTML/PDF) |
article
Closed state of both binding domains of homodimeric mGlu receptors is required for full activity
Julie Kniazeff, Anne-Sophie Bessis, Damien Maurel, Hervé Ansanay, Laurent Prézeau and Jean-Philippe Pin
Nature Structural and Molecular Biology 11, 706–713
(August 2004); doi:10.1038/nsmb794
| Abstract | Full Text (HTML/PDF) |
news and views
Toward understanding GPCR dimers
Charles Parnot and Brian Kobilka
Nature Structural and Molecular Biology 11, 691–692
(August 2004); doi:10.1038/nsmb0804-691
| Full Text (HTML/PDF) |
article
Allosteric inhibition of protein tyrosine phosphatase 1B
Christian Wiesmann, Kenneth J Barr, Jenny Kung, Jiang Zhu, Daniel A Erlanson, Wang Shen, Bruce J Fahr, Min Zhong, Lisa Taylor, Mike Randal, Robert S McDowell and Stig K Hansen
Nature Structural and Molecular Biology 11, 730–737
(August 2004); doi:10.1038/nsmb803
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article
PH domain of ELMO functions in trans to regulate Rac activation via Dock180
Mingjian Lu, Jason M Kinchen, Kent L Rossman, Cynthia Grimsley, Colin deBakker, Enrico Brugnera, Annie-Carole Tosello-Trampont, Lisa B Haney, Doris Klingele, John Sondek, Michael O Hengartner and Kodi S Ravichandran
Nature Structural and Molecular Biology 11, 756–762
(August 2004); doi:10.1038/nsmb800
| Abstract | Full Text (HTML/PDF) |
letters to nature
Chemical remodelling of cell surfaces in living animals
Jennifer A. Prescher, Danielle H. Dube and Carolyn R. Bertozzi
Nature 430, 873–877
(19 August 2004); doi:10.1038/nature02791
| First Paragraph | Full Text (HTML / PDF) |
news and views
Chemical biology: Hitting the sweet spot
David A. Tirrell
Nature 430, 837
(19 August 2004); doi:10.1038/430837a
| Full Text (HTML / PDF) |
letters to nature
SNF-6 is an acetylcholine transporter interacting with the dystrophin complex in Caenorhabditis elegans
Hongkyun Kim, Matthew J. Rogers, Janet E. Richmond and Steven L. McIntire
Nature 430, 891–896
(19 August 2004); doi:10.1038/nature02798
| First Paragraph | Full Text (HTML / PDF) |
letters to nature
Coupling of agonist binding to channel gating in an ACh-binding protein linked to an ion channel
Cecilia Bouzat, Fernanda Gumilar, Guillermo Spitzmaul, Hai-Long Wang, Diego Rayes, Scott B. Hansen, Palmer Taylor and Steven M. Sine
Nature 430, 896–900
(19 August 2004); doi:10.1038/nature02753
| First Paragraph | Full Text (HTML / PDF) |
letters to nature
Crystal structure of a complex between anthrax toxin and its host cell receptor
Eugenio Santelli, Laurie A. Bankston, Stephen H. Leppla and Robert C. Liddington
Nature 430, 905–908
(19 August 2004); doi:10.1038/nature02763
| First Paragraph | Full Text (HTML / PDF) |
news and views
Structural biology: Anthrax hijacks host receptor
James G. Bann and Scott J. Hultgren
Nature 430, 843–844
(19 August 2004); doi:10.1038/430843a
| Full Text (HTML / PDF) |
letters to nature
Cell cycle regulation of central spindle assembly
Masanori Mishima, Visnja Pavicic, Ulrike Grüneberg, Erich A. Nigg and Michael Glotzer
Nature 430, 908–913
(19 August 2004); doi:10.1038/nature02767
| First Paragraph | Full Text (HTML / PDF) |
news and views
Cell division: Timing the machine
Bruce Bowerman
Nature 430, 840–842
(19 August 2004); doi:10.1038/430840a
| Full Text (HTML / PDF) |
letters to nature
Structural basis for redox regulation of Yap1 transcription factor localization
Matthew J. Wood, Gisela Storz and Nico Tjandra
Nature 430, 917–921
(19 August 2004); doi:10.1038/nature02790
| First Paragraph | Full Text (HTML / PDF) |
article
Rapid vesicular translocation and insertion of TRP channels
Vassilios J. Bezzerides, I. Scott Ramsey, Suhas Kotecha, Anna Greka and David E. Clapham
Nature Cell Biology 6, 709–720
(August 2004); doi:10.1038/ncb1150
| Abstract | Full Text (HTML/PDF) |
news and views
Exciting trips for TRPs
Craig Montell
Nature Cell Biology 6, 690–692
(August 2004); doi:10.1038/ncb0804-690
| Full Text (HTML/PDF) |
letter
The neurotrophin-receptor-related protein NRH1 is essential for convergent extension movements
Noriaki Sasai, Yoko Nakazawa, Tomoko Haraguchi and Yoshiki Sasai
Nature Cell Biology 6, 741–748
(August 2004); doi:10.1038/ncb1158
| First Paragraph | Full Text (HTML/PDF) |
review article
Chemotaxis: signalling the way forward
Peter J. M. Van Haastert and Peter N. Devreotes
Nature Reviews Molecular Cell Biology 5, 626–634
(August 2004); doi:10.1038/nrm1435
| Summary | Full Text (HTML / PDF) |
article
NOD2 is a negative regulator of Toll-like receptor 2-mediated T helper type 1 responses
Tomohiro Watanabe, Atsushi Kitani, Peter J Murray and Warren Strober
Nature Immunology 5, 800–808
(August 2004); doi:10.1038/ni1092
| Abstract | Full Text (HTML/PDF) |
news and views
How NOD-ing off leads to Crohn disease
Luke A J O'Neill
Nature Immunology 5, 776–778
(August 2004); doi:10.1038/ni0804-776
| Full Text (HTML/PDF) |
review article
Fibrotic disease and the TH1/TH2 paradigm
Thomas A. Wynn
Nature Reviews Immunology 4, 583–594
(August 2004); doi:10.1038/nri1412
| Summary | Full Text (HTML / PDF) |
article
Mouse model of Noonan syndrome reveals cell type- and gene dosage-dependent effects of Ptpn11 mutation
Toshiyuki Araki, M Golam Mohi, Fraz A Ismat, Roderick T Bronson, Ifor R Williams, Jeffery L Kutok, Wentian Yang, Lily I Pao, D Gary Gilliland, Jonathan A Epstein and Benjamin G Neel
Nature Medicine 10, 849–857
(August 2004); doi:10.1038/nm1084
| Abstract | Full Text (HTML/PDF) |
historical perspective
Cancer genes and the pathways they control
Bert Vogelstein and Kenneth W Kinzler
Nature Medicine 10, 789–799
(August 2004); doi:10.1038/nm1087
| Abstract | Full Text (HTML/PDF) |
review article
Overweight, obesity and cancer: epidemiological evidence and proposed mechanisms
Eugenia E. Calle and Rudolf Kaaks
Nature Reviews Cancer 4, 579–591
(August 2004); doi:10.1038/nrc1408
| Summary | Full Text (HTML / PDF) |
article
Periodic gene expression program of the fission yeast cell cycle
Gabriella Rustici, Juan Mata, Katja Kivinen, Pietro Lió, Christopher J Penkett, Gavin Burns, Jacqueline Hayles, Alvis Brazma, Paul Nurse and Jürg Bähler
Nature Genetics 36, 809–817
(August 2004); doi:10.1038/ng1377
| Abstract | Full Text (HTML/PDF) |
news and views
STARTing to recycle
Gavin Sherlock
Nature Genetics 36, 795–796
(August 2004); doi:10.1038/ng0804-795
| Full Text (HTML/PDF) |
letter
Mutagenic Insertion and Chromosome Engineering Resource (MICER)
David J Adams, Patrick J Biggs, Tony Cox, Rob Davies, Louise van der Weyden, Jos Jonkers, James Smith, Bob Plumb, Ruth Taylor, Ichiko Nishijima, Yuejin Yu, Jane Rogers and Allan Bradley
Nature Genetics 36, 867–871
(August 2004); doi:10.1038/ng1388
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article
Expressing TrkC from the TrkA locus causes a subset of dorsal root ganglia neurons to switch fate
Aziz Moqrich, Taryn J Earley, James Watson, Mary Andahazy, Carey Backus, Dionisio Martin-Zanca, Douglas E Wright, Louis F Reichardt and Ardem Patapoutian
Nature Neuroscience 7, 812–818
(August 2004); doi:10.1038/nn1283
| Abstract | Full Text (HTML/PDF) |
research article
Direct proteomic mapping of the lung microvascular endothelial cell surface in vivo and in cell culture
Eberhard Durr, Jingyi Yu, Karolina M Krasinska, Lucy A Carver, John R Yates, Jacqueline E Testa III, Phil Oh and Jan E Schnitzer
Nature Biotechnology 22, 985–992
(August 2004); doi:10.1038/nbt993
| Abstract | Full Text (HTML/PDF) |
research article
Systematic identification of abundant A-to-I editing sites in the human transcriptome
Erez Y Levanon, Eli Eisenberg, Rodrigo Yelin, Sergey Nemzer, Martina Hallegger, Ronen Shemesh, Zipora Y Fligelman, Avi Shoshan, Sarah R Pollock, Dan Sztybel, Moshe Olshansky, Gideon Rechavi and Michael F Jantsch
Nature Biotechnology 22, 1001–1005
(August 2004); doi:10.1038/nbt996
| Abstract | Full Text (HTML/PDF) |
news and views
Editing the message from A to I
Kazuko Nishikura
Nature Biotechnology 22, 962–963
(August 2004); doi:10.1038/nbt0804-962
| Full Text (HTML/PDF) |
news and views
Recognizing a phosphate group
Evelyn Jabri
Nature Structural and Molecular Biology 11, 690
(August 2004); doi:10.1038/nsmb0804-690
| Full Text (HTML/PDF) |
review article
Lipid metabolic enzymes: emerging drug targets for the treatment of obesity
Yuguang Shi and Paul Burn
Nature Reviews Drug Discovery 3, 695–710
(August 2004); doi:10.1038/nrd1469
| Summary | Full Text (HTML / PDF) |
article
Novel regulatory mechanisms for the Dbl family guanine nucleotide exchange factor Cool-2/-Pix
Qiyu Feng, Daniel Baird and Richard A Cerione
The EMBO Journal Advance online publishing
(12 August 2004); doi:10.1038/sj.emboj.7600331
| Abstract | Full Text (HTML/PDF) |
article
Genetic analysis of genome-wide variation in human gene expression
Michael Morley , Cliona M. Molony, Teresa M. Weber, James L. Devlin, Kathryn G. Ewens, Richard S. Spielman and Vivian G. Cheung
Nature 430, 743–747
(12 August 2004); doi:10.1038/nature02797
| Summary | Full Text (HTML / PDF) |
news and views
Human genetics: An expression of interest
Nancy J. Cox
Nature 430, 733–734
(12 August 2004); doi:10.1038/430733a
| Full Text (HTML / PDF) |
article
The principle of temperature-dependent gating in cold- and heat-sensitive TRP channels
Thomas Voets, Guy Droogmans, Ulrich Wissenbach, Annelies Janssens, Veit Flockerzi and Bernd Nilius
Nature 430, 748–754
(12 August 2004); doi:10.1038/nature02732
| Summary | Full Text (HTML / PDF) |
letters to nature
MicroRNAs act sequentially and asymmetrically to control chemosensory laterality in the nematode
Sarah Chang, Robert J. Johnston Jr, Christian Frøkjær-Jensen, Shawn Lockery and Oliver Hobert
Nature 430, 785–789
(12 August 2004); doi:10.1038/nature02752
| First Paragraph | Full Text (HTML / PDF) |
letters to nature
Reaction mechanism determines NMDA receptor response to repetitive stimulation
Gabriela Popescu, Antoine Robert, James R. Howe and Anthony Auerbach
Nature 430, 790–793
(12 August 2004); doi:10.1038/nature02775
| First Paragraph | Full Text (HTML / PDF) |
letters to nature
Regulation of innate and adaptive immune responses by MAP kinase phosphatase 5
Yongliang Zhang, Joseph N. Blattman, Norman J. Kennedy, Julie Duong, Thang Nguyen, Ying Wang, Roger J. Davis, Philip D. Greenberg, Richard A. Flavell and Chen Dong
Nature 430, 793–797
(12 August 2004); doi:10.1038/nature02764
| First Paragraph | Full Text (HTML / PDF) |
letters to nature
Rb inactivation promotes genomic instability by uncoupling cell cycle progression from mitotic control
Eva Hernando, Zaher Nahlé , Gloria Juan, Elena Diaz-Rodriguez, Miguel Alaminos, Michael Hemann, Loren Michel, Vivek Mittal, William Gerald, Robert Benezra, Scott W. Lowe and Carlos Cordon-Cardo
Nature 430, 797–802
(12 August 2004); doi:10.1038/nature02820
| First Paragraph | Full Text (HTML / PDF) |
letters to nature
Electron microscopic analysis of KvAP voltage-dependent K+ channels in an open conformation
Qiu-Xing Jiang, Da-Neng Wang and Roderick MacKinnon
Nature 430, 806–810
(12 August 2004); doi:10.1038/nature02735
| First Paragraph | Full Text (HTML / PDF) |
article
SMYD3 encodes a histone methyltransferase involved in the proliferation of cancer cells
Ryuji Hamamoto, Yoichi Furukawa, Masashi Morita, Yuko Iimura, Fabio Pittella Silva, Meihua Li, Ryuichiro Yagyu and Yusuke Nakamura
Nature Cell Biology 6, 731–740
(August 2004); doi:10.1038/ncb1151
| Abstract | Full Text (HTML/PDF) |
news and views
From chromatin to cancer: a new histone lysine methyltransferase enters the mix
Robert J. Sims 3rd and Danny Reinberg
Nature Cell Biology 6, 685–687
(August 2004); doi:10.1038/ncb0804-685
| Full Text (HTML/PDF) |
letter
RGM and its receptor neogenin regulate neuronal survival
Eiji Matsunaga, Servane Tauszig-Delamasure, Philippe P. Monnier, Bernhard K. Mueller, Stephen M. Strittmatter, Patrick Mehlen and Alain Chédotal
Nature Cell Biology 6, 749–755
(August 2004); doi:10.1038/ncb1157
| First Paragraph | Full Text (HTML/PDF) |
review article
The co-workers of actin filaments: from cell structures to signals
Céline Revenu, Rafika Athman, Sylvie Robine and Daniel Louvard
Nature Reviews Molecular Cell Biology 5, 635–646
(August 2004); doi:10.1038/nrm1437
| Summary | Full Text (HTML / PDF) |
article
CD4 enhances T cell sensitivity to antigen by coordinating Lck accumulation at the immunological synapse
Qi-Jing Li, Aaron R Dinner, Shuyan Qi, Darrell J Irvine, Johannes B Huppa, Mark M Davis and Arup K Chakraborty
Nature Immunology 5, 791–799
(August 2004); doi:10.1038/ni1095
| Abstract | Full Text (HTML/PDF) |
news and views
Self help for T cells
Eric Hailman and Paul M Allen
Nature Immunology 5, 780–781
(August 2004); doi:10.1038/ni0804-780
| Full Text (HTML/PDF) |
perspectives
Opinion: Inflammation and necrosis promote tumour growth
Jukka Vakkila and Michael T. Lotze
Nature Reviews Immunology 4, 641–648
(August 2004); doi:10.1038/nri1415
| Summary | Full Text (HTML / PDF) |
letter
Progenitor cell trafficking is regulated by hypoxic gradients through HIF-1 induction of SDF-1
Daniel J Ceradini, Anita R Kulkarni, Matthew J Callaghan, Oren M Tepper, Nicholas Bastidas, Mark E Kleinman, Jennifer M Capla, Robert D Galiano, Jamie P Levine and Geoffrey C Gurtner
Nature Medicine 10, 858–864
(August 2004); doi:10.1038/nm1075
| First Paragraph | Full Text (HTML/PDF) |
news and views
Type 1 diabetes: focus on prevention
Harald von Boehmer
Nature Medicine 10, 783–784
(August 2004); doi:10.1038/nm0804-783
| Full Text (HTML/PDF) |
review article
Pathways of apoptotic and non-apoptotic death in tumour cells
Hitoshi Okada and Tak W. Mak
Nature Reviews Cancer 4, 592–603
(August 2004); doi:10.1038/nrc1412
| Summary | Full Text (HTML / PDF) |
letter
Heterozygous TGFBR2 mutations in Marfan syndrome
Takeshi Mizuguchi, Gwenaëlle Collod-Beroud, Takushi Akiyama, Marianne Abifadel, Naoki Harada, Takayuki Morisaki, Delphine Allard, Mathilde Varret, Mireille Claustres, Hiroko Morisaki, Makoto Ihara, Akira Kinoshita, Koh-ichiro Yoshiura, Claudine Junien, Tadashi Kajii, Guillaume Jondeau, Tohru Ohta, Tatsuya Kishino, Yoichi Furukawa, Yusuke Nakamura, Norio Niikawa, Catherine Boileau and Naomichi Matsumoto
Nature Genetics 36, 855–860
(August 2004); doi:10.1038/ng1392
| First Paragraph | Full Text (HTML/PDF) |
news and views
TGFβ signaling in health and disease
Rosemary J Akhurst
Nature Genetics 36, 790–792
(August 2004); doi:10.1038/ng0804-790
| Full Text (HTML/PDF) |
article
Continuing role for mouse Numb and Numbl in maintaining progenitor cells during cortical neurogenesis
Petur H Petersen, Kaiyong Zou, Stefan Krauss and Weimin Zhong
Nature Neuroscience 7, 803–811
(August 2004); doi:10.1038/nn1289
| Abstract | Full Text (HTML/PDF) |
news and views
Controlling neuron number: does Numb do the math?
David R Castañeda–Castellanos and Arnold R Kriegstein
Nature Neuroscience 7, 793–794
(August 2004); doi:10.1038/nn0804-793
| Full Text (HTML/PDF) |
research article
Polyvalent dendrimer glucosamine conjugates prevent scar tissue formation
Sunil Shaunak, Sharyn Thomas, Elisabetta Gianasi, Antony Godwin, Emma Jones, Ian Teo, Kamiar Mireskandari, Philip Luthert, Ruth Duncan, Steve Patterson, Peng Khaw and Steve Brocchini
Nature Biotechnology 22, 977–984
(August 2004); doi:10.1038/nbt995
| Abstract | Full Text (HTML/PDF) |
research article
In silico simulation of biological network dynamics
Lukasz Salwinski and David Eisenberg
Nature Biotechnology 22, 1017–1019
(August 2004); doi:10.1038/nbt991
| First Paragraph | Full Text (HTML/PDF) |
news and views
The need for speed in stochastic simulation
Larry Lok
Nature Biotechnology 22, 964–965
(August 2004); doi:10.1038/nbt0804-964
| Full Text (HTML/PDF) |
article
DNA binding and nucleotide flipping by the human DNA repair protein AGT
Douglas S Daniels, Tammy T Woo, Kieu X Luu, David M Noll, Neil D Clarke, Anthony E Pegg and John A Tainer
Nature Structural and Molecular Biology 11, 714–720
(August 2004); doi:10.1038/nsmb791
| Abstract | Full Text (HTML/PDF) |
news and views
Reversing DNA damage with a directional bias
Thomas J Begley and Leona D Samson
Nature Structural and Molecular Biology 11, 688–690
(August 2004); doi:10.1038/nsmb0804-688
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letters to nature
Sirtuin activators mimic caloric restriction and delay ageing in metazoans
Jason G. Wood, Blanka Rogina, Siva Lavu, Konrad Howitz, Stephen L. Helfand, Marc Tatar and David Sinclair
Nature 430, 686–689
(05 August 2004); doi:10.1038/nature02789
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letters to nature
Planar cell polarity signalling controls cell division orientation during zebrafish gastrulation
Ying Gong, Chunhui Mo and Scott E. Fraser
Nature 430, 689–693
(05 August 2004); doi:10.1038/nature02796
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letters to nature
De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-κB signalling
Ingrid E. Wertz, Karen M. O'Rourke, Honglin Zhou, Michael Eby, L. Aravind, Somasekar Seshagiri, Ping Wu, Christian Wiesmann, Rohan Baker, David L. Boone, Averil Ma, Eugene V. Koonin and Vishva M. Dixit
Nature 430, 694–699
(05 August 2004); doi:10.1038/nature02794
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letters to nature
High mutation rate and predominance of insertions in the Caenorhabditis elegans nuclear genome
Dee R. Denver, Krystalynne Morris, Michael Lynch and W. Kelley Thomas
Nature 430, 679–682
(05 August 2004); doi:10.1038/nature02697
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news and views
Genomes: Worming into genetic instability
Susan M. Rosenberg and P. J. Hastings
Nature 430, 625–626
(05 August 2004); doi:10.1038/430625a
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review article
Pathways towards and away from Alzheimer's disease
Mark P. Mattson
Nature 430, 631–639
(05 August 2004); doi:10.1038/nature02621
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letter
The CDC-14 phosphatase controls developmental cell-cycle arrest in C. elegans
R. Mako Saito, Audrey Perreault, Bethan Peach, John S. Satterlee and Sander van den Heuvel
Nature Cell Biology 6, 777–783
(August 2004); doi:10.1038/ncb1154
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news and views
Developmental quiescence: Cdc14 moonlighting in G1
Edward T. Kipreos
Nature Cell Biology 6, 693–695
(August 2004); doi:10.1038/ncb0804-693
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letter
Neogenin mediates the action of repulsive guidance molecule
Srikanth Rajagopalan, Lutz Deitinghoff, Denise Davis, Sabine Conrad, Thomas Skutella, Alain Chedotal, Bernhard K. Mueller and Stephen M. Strittmatter
Nature Cell Biology 6, 756–762
(August 2004); doi:10.1038/ncb1156
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review article
α-catenin: at the junction of intercellular adhesion and actin dynamics
Agnieszka Kobielak and Elaine Fuchs
Nature Reviews Molecular Cell Biology 5, 614–625
(August 2004); doi:10.1038/nrm1433
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article
CD8+ T cell contraction is controlled by early inflammation
Vladimir P Badovinac, Brandon B Porter and John T Harty
Nature Immunology 5, 809–817
(August 2004); doi:10.1038/ni1098
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article
RabGEF1 is a negative regulator of mast cell activation and skin inflammation
See-Ying Tam, Mindy Tsai, John N Snouwaert, Janet Kalesnikoff, Didier Scherrer, Susumu Nakae, Devavani Chatterjea, Donna M Bouley and Stephen J Galli
Nature Immunology 5, 844–852
(August 2004); doi:10.1038/ni1093
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review article
Matrix metalloproteinases as modulators of inflammation and innate immunity
William C. Parks , Carole L. Wilson and Yolanda S. López-Boado
Nature Reviews Immunology 4, 617–629
(August 2004); doi:10.1038/nri1418
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article
Staphylococcus aureus protein A induces airway epithelial inflammatory responses by activating TNFR1
Marisa I Gómez, Aram Lee, Bharat Reddy, Amanda Muir, Grace Soong, Allyson Pitt, Ambrose Cheung and Alice Prince
Nature Medicine 10, 842–848
(August 2004); doi:10.1038/nm1079
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news and views
Staphylococcal protein A inflames the lungs
Birgitta Henriques Normark, Staffan Normark and Anna Norrby-Teglund
Nature Medicine 10, 780–781
(August 2004); doi:10.1038/nm0804-780
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brief communication
Vascular endothelial growth factor receptor-3 mediates induction of corneal alloimmunity
Lu Chen, Pedram Hamrah, Claus Cursiefen, Qiang Zhang, Bronislaw Pytowski, J Wayne Streilein and M Reza Dana
Nature Medicine 10, 813–815
(August 2004); doi:10.1038/nm1078
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perspectives
Opinion: Integrated global profiling of cancer
Samir Hanash
Nature Reviews Cancer 4, 638–644
(August 2004); doi:10.1038/nrc1414
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article
The imprinted signaling protein XLαs is required for postnatal adaptation to feeding
Antonius Plagge, Emma Gordon, Wendy Dean, Romina Boiani, Saverio Cinti, Jo Peters and Gavin Kelsey
Nature Genetics 36, 818–826
(August 2004); doi:10.1038/ng1397
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letter
A cis-acting control region is required exclusively for the tissue-specific imprinting of Gnas
Christine M Williamson, Simon T Ball, Wade T Nottingham, Judith A Skinner, Antonius Plagge, Martin D Turner, Nicola Powles, Tertius Hough, David Papworth, William D Fraser, Mark Maconochie and Jo Peters
Nature Genetics 36, 894–899
(August 2004); doi:10.1038/ng1398
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news and views
Complex imprinting
Arthur L Beaudet
Nature Genetics 36, 793–795
(August 2004); doi:10.1038/ng0804-793
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article
Epigenetic programming by maternal behavior
Ian C G Weaver, Nadia Cervoni, Frances A Champagne, Ana C D'Alessio, Shakti Sharma, Jonathan R Seckl, Sergiy Dymov, Moshe Szyf and Michael J Meaney
Nature Neuroscience 7, 847–854
(August 2004); doi:10.1038/nn1276
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news and views
Mothering style and methylation
Robert M Sapolsky
Nature Neuroscience 7, 791–792
(August 2004); doi:10.1038/nn0804-791
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article
Olfactory receptor neuron axon targeting: intrinsic transcriptional control and hierarchical interactions
Takaki Komiyama, John R Carlson and Liqun Luo
Nature Neuroscience 7, 819–825
(August 2004); doi:10.1038/nn1284
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research article
Analysis of the transcriptional complexity of Arabidopsis thaliana by massively parallel signature sequencing
Blake C Meyers, Tam H Vu, Shivakundan Singh Tej, Hassan Ghazal, Marta Matvienko, Vikas Agrawal, Jianchang Ning and Christian D Haudenschild
Nature Biotechnology 22, 1006–1011
(August 2004); doi:10.1038/nbt992
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news and views
Tagging all genes
Jeffrey F D Dean
Nature Biotechnology 22, 961–962
(August 2004); doi:10.1038/nbt0804-961
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