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The Research Library categorizes, and provides access to, all recent signaling-related research published in the Nature Publishing Group journals. The selection is deliberately broad to facilitate access to all research impacting on the signaling community. Both primary research and review articles are included, as are 'News and Views' articles.
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article
Drosophila Spire is an actin nucleation factor
Margot E. Quinlan, John E. Heuser, Eugen Kerkhoff and R. Dyche Mullins
Nature 433, 382–388
(27 January 2005); doi:10.1038/nature03241
| Summary | Full Text (HTML / PDF) |
letter
Drosophila CLASP is required for the incorporation of microtubule subunits into fluxing kinetochore fibres
Helder Maiato, Alexey Khodjakov and Conly L. Rieder
Nature Cell Biology 7, 42–47
(January 2005); doi:10.1038/ncb1207
| First Paragraph | Full Text (HTML/PDF) |
news and views
CLASP fluxes its mitotic muscles
Claire E. Walczak
Nature Cell Biology 7, 5–7
(January 2005); doi:10.1038/ncb0105-5
| Full Text (HTML/PDF) |
letter
Coupling of ER exit to microtubules through direct interaction of COPII with dynactin
Peter Watson, Rebecca Forster, Krysten J. Palmer, Rainer Pepperkok and David J. Stephens
Nature Cell Biology 7, 48–55
(January 2005); doi:10.1038/ncb1206
| First Paragraph | Full Text (HTML/PDF) |
review article
RNA polymerases I and III, growth control and cancer
Robert J. White
Nature Reviews Molecular Cell Biology 6, 69–78
(January 2005); doi:10.1038/nrm1551
| Summary | Full Text (HTML / PDF) |
article
Lethal anemia caused by interferon-β produced in mouse embryos carrying undigested DNA
Hideyuki Yoshida, Yasutaka Okabe, Kohki Kawane, Hidehiro Fukuyama and Shigekazu Nagata
Nature Immunology 6, 49–56
(January 2005); doi:10.1038/ni1146
| Abstract | Full Text (HTML/PDF) |
review article
α-Galactosylceramide therapy for autoimmune diseases: prospects and obstacles
Luc Van Kaer
Nature Reviews Immunology 5, 31–42
(January 2005); doi:10.1038/nri1531
| Summary | Full Text (HTML / PDF) |
letter
Free fatty acids regulate gut incretin glucagon-like peptide-1 secretion through GPR120
Akira Hirasawa, Keiko Tsumaya, Takeo Awaji, Susumu Katsuma, Tetsuya Adachi, Masateru Yamada, Yukihiko Sugimoto, Shunichi Miyazaki and Gozoh Tsujimoto
Nature Medicine 11, 90–94
(January 2005); doi:10.1038/nm1168
| Abstract | Full Text (HTML/PDF) |
news and views
B-cell lymphoma: suppressing a tumor suppressor
Alexander Dent
Nature Medicine 11, 22
(January 2005); doi:10.1038/nm0105-22
| Full Text (HTML/PDF) |
news and views
Inflammation and cancer: the long reach of Ras
Michael Karin
Nature Medicine 11, 20–21
(January 2005); doi:10.1038/nm0105-20
| Full Text (HTML/PDF) |
review article
Integrin-linked kinase: a cancer therapeutic target unique among its ILK
Gregory Hannigan, Armelle A. Troussard and Shoukat Dedhar
Nature Reviews Cancer 5, 51–63
(January 2005); doi:10.1038/nrc1524
| Summary | Full Text (HTML / PDF) |
article
Loss of silent-chromatin looping and impaired imprinting of DLX5 in Rett syndrome
Shin-ichi Horike, Shutao Cai, Masaru Miyano, Jan-Fang Cheng and Terumi Kohwi-Shigematsu
Nature Genetics 37, 31–40
(January 2005); doi:10.1038/ng1491
| Abstract | Full Text (HTML/PDF) |
news and views
Synapsis or silence
John Schimenti
Nature Genetics 37, 11–13
(January 2005); doi:10.1038/ng0105-11
| Full Text (HTML/PDF) |
article
The MEC-4 DEG/ENaC channel of Caenorhabditis elegans touch receptor neurons transduces mechanical signals
Robert O'Hagan, Martin Chalfie and Miriam B Goodman
Nature Neuroscience 8, 43–50
(January 2005); doi:10.1038/nn1362
| Abstract | Full Text (HTML/PDF) |
news and views
Metazoan mechanotransduction mystery finally solved
Diane Ronan and Peter Gillespie
Nature Neuroscience 8, 7–8
(January 2005); doi:10.1038/nn0105-7
| Full Text (HTML/PDF) |
research article
Coordinate dual-gene transgenesis by lentiviral vectors carrying synthetic bidirectional promoters
Mario Amendola, Mary Anna Venneri, Alessandra Biffi, Elisa Vigna and Luigi Naldini
Nature Biotechnology 23, 108–116
(January 2005); doi:10.1038/nbt1049
| First Paragraph | Full Text (HTML/PDF) |
research article
Protein tagging and detection with engineered self-assembling fragments of green fluorescent protein
Stéphanie Cabantous, Thomas C Terwilliger and Geoffrey S Waldo
Nature Biotechnology 23, 102–107
(January 2005); doi:10.1038/nbt1044
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article
Unique binding interactions among Ubc9, SUMO and RanBP2 reveal a mechanism for SUMO paralog selection
Michael H Tatham, Suhkmann Kim, Ellis Jaffray, Jing Song, Yuan Chen and Ronald T Hay
Nature Structural and Molecular Biology 12, 67–74
(January 2005); doi:10.1038/nsmb878
| Abstract | Full Text (HTML/PDF) |
article
Structural characterization of a type III secretion system filament protein in complex with its chaperone
Calvin K Yip, B Brett Finlay and Natalie C J Strynadka
Nature Structural and Molecular Biology 12, 75–81
(January 2005); doi:10.1038/nsmb879
| Abstract | Full Text (HTML/PDF) |
article
LAMP, a new imaging assay of gap junctional communication unveils that Ca2+ influx inhibits cell coupling
Kenneth Dakin, YuRui Zhao and Wen-Hong Li
Nature Methods 2, 55–62
(January 2005); doi:10.1038/nmeth730
| Abstract | Full Text (HTML/PDF) |
news and views
Illuminating gap junctions
David C Spray
Nature Methods 2, 12–14
(January 2005); doi:10.1038/nmeth0105-12
| Abstract | Full Text (HTML/PDF) |
article
Viral modulation of NK cell immunity
Melissa B. Lodoen and Lewis L. Lanier
Nature Reviews Microbiology 3, 59–69
(January 2005); doi:10.1038/nrmicro1066
| Abstract | Full Text (HTML/PDF) |
article
Role of the proto-oncogene Pokemon in cellular transformation and ARF repression
Takahiro Maeda, Robin M. Hobbs, Taha Merghoub, Ilhem Guernah, Arthur Zelent, Carlos Cordon-Cardo, Julie Teruya-Feldstein and Pier Paolo Pandolfi
Nature 433, 278–285
(20 January 2005); doi:10.1038/nature03203
| Summary | Full Text (HTML / PDF) |
letters to nature
Protein kinase A signalling via CREB controls myogenesis induced by Wnt proteins
Alice E. Chen, David D. Ginty and Chen-Ming Fan
Nature 433, 317–322
(20 January 2005); doi:10.1038/nature03126
| First Paragraph | Full Text (HTML / PDF) |
news and views
Signal transduction: A new canon
Olivier Pourquié
Nature 433, 208–209
(20 January 2005); doi:10.1038/433208a
| Full Text (HTML / PDF) |
letter
The human mitotic checkpoint protein BubR1 regulates chromosome-spindle attachments
Michael A. Lampson and Tarun M. Kapoor
Nature Cell Biology 7, 93–98
(January 2005); doi:10.1038/ncb1208
| First Paragraph | Full Text (HTML/PDF) |
letter
Impaired permeability to Ins(1,4,5)P3 in a mutant connexin underlies recessive hereditary deafness
Martina Beltramello, Valeria Piazza, Feliksas F. Bukauskas, Tullio Pozzan and Fabio Mammano
Nature Cell Biology 7, 63–69
(January 2005); doi:10.1038/ncb1205
| First Paragraph | Full Text (HTML/PDF) |
news and views
Hearing the messenger: Ins(1,4,5)P3 and deafness
Roberto Bruzzone and Martine Cohen-Salmon
Nature Cell Biology 7, 14–16
(January 2005); doi:10.1038/ncb0105-14
| Full Text (HTML/PDF) |
review article
The nuclear lamina comes of age
Yosef Gruenbaum, Ayelet Margalit, Robert D. Goldman, Dale K. Shumaker and Katherine L. Wilson
Nature Reviews Molecular Cell Biology 6, 21–31
(January 2005); doi:10.1038/nrm1550
| Summary | Full Text (HTML / PDF) |
review article
ADAMs: key components in EGFR signalling and development
Carl P. Blobel
Nature Reviews Molecular Cell Biology 6, 32–43
(January 2005); doi:10.1038/nrm1548
| Summary | Full Text (HTML / PDF) |
article
Dendritic epidermal T cells regulate skin homeostasis through local production of insulin-like growth factor 1
Leslie L Sharp, Julie M Jameson, Gabrielle Cauvi and Wendy L Havran
Nature Immunology 6, 73–79
(January 2005); doi:10.1038/ni1152
| Abstract | Full Text (HTML/PDF) |
article
Dynamic molecular interactions linking the T cell antigen receptor to the actin cytoskeleton
Mira Barda-Saad, Alex Braiman, Rachel Titerence, Stephen C Bunnell, Valarie A Barr and Lawrence E Samelson
Nature Immunology 6, 80–89
(January 2005); doi:10.1038/ni1143
| Abstract | Full Text (HTML/PDF) |
review article
Immunoregulatory functions of surfactant proteins
Jo Rae Wright
Nature Reviews Immunology 5, 58–68
(January 2005); doi:10.1038/nri1528
| Summary | Full Text (HTML / PDF) |
article
Stat3 links activated keratinocytes and immunocytes required for development of psoriasis in a novel transgenic mouse model
Shigetoshi Sano, Keith Syson Chan, Steve Carbajal, John Clifford, Mary Peavey, Kaoru Kiguchi, Satoshi Itami, Brian J Nickoloff and John DiGiovanni
Nature Medicine 11, 43–49
(January 2005); doi:10.1038/nm1162
| Abstract | Full Text (HTML/PDF) |
news and views
Psoriasis: more than skin deep
Mark R Pittelkow
Nature Medicine 11, 17–18
(January 2005); doi:10.1038/nm0105-17
| Full Text (HTML/PDF) |
letter
Early events in lupus humoral autoimmunity suggest initiation through molecular mimicry
Micah T McClain, Latisha D Heinlen, Gregory J Dennis, Jon Roebuck, John B Harley and Judith A James
Nature Medicine 11, 85–89
(January 2005); doi:10.1038/nm1167
| First Paragraph | Full Text (HTML/PDF) |
review article
Aurora-A — A guardian of poles
Tomotoshi Marumoto, Dongwei Zhang and Hideyuki Saya
Nature Reviews Cancer 5, 42–50
(January 2005); doi:10.1038/nrc1526
| Summary | Full Text (HTML / PDF) |
brief communication
Insulin signaling in the nervous system regulates ethanol intoxication in Drosophila melanogaster
Ammon B Corl, Aylin R Rodan and Ulrike Heberlein
Nature Neuroscience 8, 18–19
(January 2005); doi:10.1038/nn1363
| First Paragraph | Full Text (HTML/PDF) |
research article
Immunoaffinity profiling of tyrosine phosphorylation in cancer cells
John Rush, Albrecht Moritz, Kimberly A Lee, Ailan Guo, Valerie L Goss, Erik J Spek, Hui Zhang, Xiang-Ming Zha, Roberto D Polakiewicz and Michael J Comb
Nature Biotechnology 23, 94–101
(January 2005); doi:10.1038/nbt1046
| First Paragraph | Full Text (HTML/PDF) |
news and views
An enriched look at tyrosine phosphorylation
Thomas P Conrads and Timothy D Veenstra
Nature Biotechnology 23, 36–37
(January 2005); doi:10.1038/nbt0105-36
| Full Text (HTML/PDF) |
article
Conformational changes in the Arp2/3 complex leading to actin nucleation
Avital A Rodal, Olga Sokolova, Deborah B Robins, Karen M Daugherty, Simon Hippenmeyer, Howard Riezman, Nikolaus Grigorieff and Bruce L Goode
Nature Structural and Molecular Biology 12, 26–31
(January 2005); doi:10.1038/nsmb870
| Abstract | Full Text (HTML/PDF) |
article
Bicarbonate activation of adenylyl cyclase via promotion of catalytic active site closure and metal recruitment
Clemens Steegborn, Tatiana N Litvin, Lonny R Levin, Jochen Buck and Hao Wu
Nature Structural and Molecular Biology 12, 32–37
(January 2005); doi:10.1038/nsmb880
| Abstract | Full Text (HTML/PDF) |
news and views
A seminal study of soluble adenylyl cyclase
John J G Tesmer
Nature Structural and Molecular Biology 12, 7–8
(January 2005); doi:10.1038/nsmb0105-7
| Full Text (HTML/PDF) |
article
Crystal structure of bet3 reveals a novel mechanism for Golgi localization of tethering factor TRAPP
Yeon-Gil Kim, Eun Ju Sohn, Jawon Seo, Kong-Joo Lee, Heung-Soo Lee, Inhwan Hwang, Malcolm Whiteway, Michael Sacher and Byung-Ha Oh
Nature Structural and Molecular Biology 12, 38–45
(January 2005); doi:10.1038/nsmb871
| Abstract | Full Text (HTML/PDF) |
article
Mapping DNA-protein interactions in large genomes by sequence tag analysis of genomic enrichment
Jonghwan Kim, Akshay A Bhinge, Xochitl C Morgan and Vishwanath R Iyer
Nature Methods 2, 47–53
(January 2005); doi:10.1038/nmeth726
| Abstract | Full Text (HTML/PDF) |
review article
LPS, TLR4 and infectious disease diversity
Samuel I. Miller, Robert K. Ernst and Martin W. Bader
Nature Reviews Microbiology 3, 36–46
(January 2005); doi:10.1038/nrmicro1068
| Abstract | Full Text (HTML/PDF) |
research article
FGF-20 and DKK1 are transcriptional targets of β-catenin and FGF-20 is implicated in cancer and development
Mario N Chamorro, Donald R Schwartz, Alin Vonica, Ali H Brivanlou, Kathleen R Cho and Harold E Varmus
EMBO Journal 24, 73–84
(January 2005); doi:10.1038/sj.emboj.7600460
| Abstract | Full Text (HTML/PDF) |
letters to nature
Binding of brassinosteroids to the extracellular domain of plant receptor kinase BRI1
Toshinori Kinoshita , Ana Caño-Delgado, Hideharu Seto, Sayoko Hiranuma, Shozo Fujioka, Shigeo Yoshida and Joanne Chory
Nature 433, 167–171
(13 January 2005); doi:10.1038/nature03227
| First Paragraph | Full Text (HTML / PDF) |
letters to nature
Stabilization of microtubule dynamics at anaphase onset promotes chromosome segregation
Toru Higuchi and Frank Uhlmann
Nature 433, 171–176
(13 January 2005); doi:10.1038/nature03240
| First Paragraph | Full Text (HTML / PDF) |
article
Akt and 14-3-3η regulate Miz1 to control cell-cycle arrest after DNA damage
Michael Wanzel, Daniela Kleine-Kohlbrecher, Steffi Herold, Andreas Hock, Katrien Berns, Jongsun Park, Brian Hemmings and Martin Eilers
Nature Cell Biology 7, 30–41
(January 2005); doi:10.1038/ncb1202
| Abstract | Full Text (HTML/PDF) |
letter
A critical role for Cyclin E in cell fate determination in the central nervous system of Drosophila melanogaster
Christian Berger, S. K. Pallavi, Mohit Prasad, L. S. Shashidhara and Gerhard M. Technau
Nature Cell Biology 7, 56–62
(January 2005); doi:10.1038/ncb1203
| First Paragraph | Full Text (HTML/PDF) |
news and views
Cyclin E at the centre of an identity crisis
William Chia and Sergei N. Prokopenko
Nature Cell Biology 7, 3–5
(January 2005); doi:10.1038/ncb0105-3
| Full Text (HTML/PDF) |
letter
IAPs are functionally non-equivalent and regulate effector caspases through distinct mechanisms
Tencho Tenev, Anna Zachariou, Rebecca Wilson, Mark Ditzel and Pascal Meier
Nature Cell Biology 7, 70–77
(January 2005); doi:10.1038/ncb1204
| First Paragraph | Full Text (HTML/PDF) |
news and views
Nuclear pore complexes: Round the bend?
Wolfram Antonin and Iain W. Mattaj
Nature Cell Biology 7, 10–12
(January 2005); doi:10.1038/ncb0105-10
| Full Text (HTML/PDF) |
news and views
Ub in charge: Regulating E2 enzyme nuclear import
Xiang-Dong Zhang and Michael J Matunis
Nature Cell Biology 7, 12–14
(January 2005); doi:10.1038/ncb0105-12
| Full Text (HTML/PDF) |
review article
Function and regulation of cullin-RING ubiquitin ligases
Matthew D. Petroski and Raymond J. Deshaies
Nature Reviews Molecular Cell Biology 6, 9–20
(January 2005); doi:10.1038/nrm1547
| Summary | Full Text (HTML / PDF) |
review article
Focal adhesion kinase: in command and control of cell motility
Satyajit K. Mitra, Daniel A. Hanson and David D. Schlaepfer
Nature Reviews Molecular Cell Biology 6, 56–68
(January 2005); doi:10.1038/nrm1549
| Summary | Full Text (HTML / PDF) |
article
B and T lymphocyte attenuator regulates T cell activation through interaction with herpesvirus entry mediator
John R Sedy, Maya Gavrieli, Karen G Potter, Michelle A Hurchla, R Coleman Lindsley, Kai Hildner, Stefanie Scheu, Klaus Pfeffer, Carl F Ware, Theresa L Murphy and Kenneth M Murphy
Nature Immunology 6, 90–98
(January 2005); doi:10.1038/ni1144
| Abstract | Full Text (HTML/PDF) |
review article
Protein tyrosine phosphatases and the immune response
Tomas Mustelin, Torkel Vang and Nunzio Bottini
Nature Reviews Immunology 5, 43–57
(January 2005); doi:10.1038/nri1530
| Summary | Full Text (HTML / PDF) |
letter
Inhibitors of histone deacetylases induce tumor-selective apoptosis through activation of the death receptor pathway
Alessandra Insinga, Silvia Monestiroli, Simona Ronzoni, Vania Gelmetti, Francesco Marchesi, Andrea Viale, Lucia Altucci, Clara Nervi, Saverio Minucci and Pier Giuseppe Pelicci
Nature Medicine 11, 71–76
(January 2005); doi:10.1038/nm1160
| First Paragraph | Full Text (HTML/PDF) |
letter
Tumor-selective action of HDAC inhibitors involves TRAIL induction in acute myeloid leukemia cells
Angela Nebbioso, Nicole Clarke, Emilie Voltz, Emmanuelle Germain, Concetta Ambrosino, Paola Bontempo, Rosana Alvarez, Ettore M Schiavone, Felicetto Ferrara, Francesco Bresciani, Alessandro Weisz, Angel R de Lera, Hinrich Gronemeyer and Lucia Altucci
Nature Medicine 11, 77–84
(January 2005); doi:10.1038/nm1161
| First Paragraph | Full Text (HTML/PDF) |
news and views
Autoimmunity and apoptosis: refusing to go quietly
Donna L Bratton and Peter M Henson
Nature Medicine 11, 26–27
(January 2005); doi:10.1038/nm0105-26
| Full Text (HTML/PDF) |
review article
Galectins as modulators of tumour progression
Fu-Tong Liu and Gabriel A. Rabinovich
Nature Reviews Cancer 5, 29–41
(January 2005); doi:10.1038/nrc1527
| Summary | Full Text (HTML / PDF) |
article
Spink5-deficient mice mimic Netherton syndrome through degradation of desmoglein 1 by epidermal protease hyperactivity
Pascal Descargues, Céline Deraison, Chrystelle Bonnart, Maaike Kreft, Mari Kishibe, Akemi Ishida-Yamamoto, Peter Elias, Yann Barrandon, Giovanna Zambruno, Arnoud Sonnenberg and Alain Hovnanian
Nature Genetics 37, 56–65
(January 2005); doi:10.1038/ng1493
| Abstract | Full Text (HTML/PDF) |
review article
RNAi-mediated pathways in the nucleus
Marjori A. Matzke and James A. Birchler
Nature Reviews Genetics 6, 24–35
(January 2005); doi:10.1038/nrg1500
| Summary | Full Text (HTML / PDF) |
article
Wnt signaling through Dishevelled, Rac and JNK regulates dendritic development
Silvana B Rosso, Daniel Sussman, Anthony Wynshaw-Boris and Patricia C Salinas
Nature Neuroscience 8, 34–42
(January 2005); doi:10.1038/nn1374
| Abstract | Full Text (HTML/PDF) |
research article
Ex vivo generation of fully mature human red blood cells from hematopoietic stem cells
Marie-Catherine Giarratana, Ladan Kobari, Hélène Lapillonne, David Chalmers, Laurent Kiger, Thérèse Cynober, Michael C Marden, Henri Wajcman and Luc Douay
Nature Biotechnology 23, 69–74
(January 2005); doi:10.1038/nbt1047
| Abstract | Full Text (HTML/PDF) |
news and views
Banking on red blood cells
Narla Mohandas
Nature Biotechnology 23, 35–36
(January 2005); doi:10.1038/nbt0105-35
| Full Text (HTML/PDF) |
research article
Microfluidic sorting of mammalian cells by optical force switching
Mark M Wang, Eugene Tu, Daniel E Raymond, Joon Mo Yang, Haichuan Zhang, Norbert Hagen, Bob Dees, Elinore M Mercer, Anita H Forster, Ilona Kariv, Philippe J Marchand and William F Butler
Nature Biotechnology 23, 83–87
(January 2005); doi:10.1038/nbt1050
| First Paragraph | Full Text (HTML/PDF) |
review article
Data integration: challenges for drug discovery
David B. Searls
Nature Reviews Drug Discovery 4, 45–58
(January 2005); doi:10.1038/nrd1608
| Summary | Full Text (HTML / PDF) |
research article
Polyene-lipids: A new tool to image lipids
Lars Kuerschner, Christer S Ejsing, Kim Ekroos, Andrej Shevchenko, Kurt I Anderson and Christoph Thiele
Nature Methods 2, 39–45
(January 2005); doi:10.1038/nmeth728
| Summary | Full Text (HTML / PDF) |
news and views
Brilliant lipids
Gerrit van Meer and Rob M J Liskamp
Nature Methods 2, 14–15
(January 2005); doi:10.1038/nmeth0105-14
| Full Text (HTML / PDF) |
review article
Kinomics: methods for deciphering the kinome
Sam A Johnson and Tony Hunter
Nature Methods 2, 17–25
(January 2005); doi:10.1038/nmeth731
| Summary | Full Text (HTML / PDF) |
article
The PIN auxin efflux facilitator network controls growth and patterning in Arabidopsis roots
Ikram Blilou, Jian Xu, Marjolein Wildwater, Viola Willemsen, Ivan Paponov, Jiří Friml, Renze Heidstra, Mitsuhiro Aida, Klaus Palme and Ben Scheres
Nature 433, 39–44
(06 January 2005); doi:10.1038/nature03184
| Summary | Full Text (HTML / PDF) |
letters to nature
β-Lactam antibiotics offer neuroprotection by increasing glutamate transporter expression
Jeffrey D. Rothstein, Sarjubhai Patel, Melissa R. Regan, Christine Haenggeli, Yanhua H. Huang, Dwight E. Bergles, Lin Jin, Margaret Dykes Hoberg, Svetlana Vidensky, Dorothy S. Chung, Shuy Vang Toan, Lucie I. Bruijn, Zao-zhong Su, Pankaj Gupta and Paul B. Fisher
Nature 433, 73–77
(06 January 2005); doi:10.1038/nature03180
| First Paragraph | Full Text (HTML / PDF) |
article
Chronophin, a novel HAD-type serine protein phosphatase, regulates cofilin-dependent actin dynamics
Antje Gohla, Jörg Birkenfeld and Gary M. Bokoch
Nature Cell Biology 7, 21–29
(January 2005); doi:10.1038/ncb1201
| Abstract | Full Text (HTML/PDF) |
news and views
A phosphatase for cofilin to be HAD
O'Neil Wiggan, Barbara W. Bernstein and James R. Bamburg
Nature Cell Biology 7, 8–9
(January 2005); doi:10.1038/ncb0105-8
| Full Text (HTML/PDF) |
letter
Negative regulation of EGFR signalling through integrin-α1β1-mediated activation of protein tyrosine phosphatase TCPTP
Elina Mattila, Teijo Pellinen, Jonna Nevo, Karoliina Vuoriluoto, Antti Arjonen and Johanna Ivaska
Nature Cell Biology 7, 78–85
(January 2005); doi:10.1038/ncb1209
| First Paragraph | Full Text (HTML/PDF) |
letter
Drosophila Smoothened phosphorylation sites essential for Hedgehog signal transduction
Sergey Apionishev, Natalya M. Katanayeva, Steven A. Marks, Daniel Kalderon and Andrew Tomlinson
Nature Cell Biology 7, 86–92
(January 2005); doi:10.1038/ncb1210
| First Paragraph | Full Text (HTML/PDF) |
review article
p53: traffic cop at the crossroads of DNA repair and recombination
Sagar Sengupta and Curtis C. Harris
Nature Reviews Molecular Cell Biology 6, 44–55
(January 2005); doi:10.1038/nrm1546
| Summary | Full Text (HTML / PDF) |
article
Signaling by the kinase MINK is essential in the negative selection of autoreactive thymocytes
Nami McCarty, Silke Paust, Koichi Ikizawa, Ippeita Dan, Xiaoyan Li and Harvey Cantor
Nature Immunology 6, 65–72
(January 2005); doi:10.1038/ni1145
| Abstract | Full Text (HTML/PDF) |
news and views
Signaling negative selection: is MINK the missing link?
Ed Palmer
Nature Immunology 6, 9–10
(January 2005); doi:10.1038/ni0105-9
| Full Text (HTML/PDF) |
article
Antimicrobial psoriasin (S100A7) protects human skin from Escherichia coli infection
Regine Gläser, Jürgen Harder, Hans Lange, Joachim Bartels, Enno Christophers and Jens-Michael Schröder
Nature Immunology 6, 57–64
(January 2005); doi:10.1038/ni1142
| Abstract | Full Text (HTML/PDF) |
news and views
An important clue: fingerprints point to psoriasin in defense against E. coli
Charles L Bevins
Nature Immunology 6, 12–13
(January 2005); doi:10.1038/ni0105-12
| Full Text (HTML/PDF) |
perspectives
Innate and adaptive immunity: specificities and signaling hierarchies revisited
Eric Vivier and Bernard Malissen
Nature Immunology 6, 17–21
(January 2005); doi:10.1038/ni1153
| Abstract | Full Text (HTML/PDF) |
review article
WNT signalling and haematopoiesis: a WNT-WNT situation
Frank J.T. Staal and Hans C. Clevers
Nature Reviews Immunology 5, 21–30
(January 2005); doi:10.1038/nri1529
| Summary | Full Text (HTML / PDF) |
review article
The neuropathogenesis of AIDS
Francisco González-Scarano and Julio Martín-García
Nature Reviews Immunology 5, 69–81
(January 2005); doi:10.1038/nri1527
| Summary | Full Text (HTML / PDF) |
review article
Osteoblasts in prostate cancer metastasis to bone
Christopher J. Logothetis and Sue-Hwa Lin
Nature Reviews Cancer 5, 21–28
(January 2005); doi:10.1038/nrc1528
| Summary | Full Text (HTML / PDF) |
article
An oncogenic KRAS2 expression signature identified by cross-species gene-expression analysis
Alejandro Sweet-Cordero, Sayan Mukherjee, Aravind Subramanian, Han You, Jeffrey J Roix, Christine Ladd-Acosta, Jill Mesirov, Todd R Golub and Tyler Jacks
Nature Genetics 37, 48–55
(January 2005); doi:10.1038/ng1490
| Abstract | Full Text (HTML/PDF) |
news and views
Cross-species comparisons of cancer signaling
Thomas G Graeber and Charles L Sawyers
Nature Genetics 37, 7–8
(January 2005); doi:10.1038/ng0105-7
| Full Text (HTML/PDF) |
letter
EGFR signaling attenuates Groucho-dependent repression to antagonize Notch transcriptional output
Peleg Hasson, Nirit Egoz, Clint Winkler, Gloria Volohonsky, Songtao Jia, Tama Dinur, Talila Volk, Albert J Courey and Ze'ev Paroush
Nature Genetics 37, 101–105
(January 2005); doi:10.1038/ng1486
| First Paragraph | Full Text (HTML/PDF) |
review article
Dysregulation of the TSC-mTOR pathway in human disease
Ken Inoki, Michael N Corradetti and Kun-Liang Guan
Nature Genetics 37, 19–24
(January 2005); doi:10.1038/ng1494
| Abstract | Full Text (HTML/PDF) |
review article
Drosophila, the golden bug, emerges as a tool for human genetics
Ethan Bier
Nature Reviews Genetics 6, 9–23
(January 2005); doi:10.1038/nrg1503
| Summary | Full Text (HTML / PDF) |
article
Protection of p27Kip1 mRNA by quaking RNA binding proteins promotes oligodendrocyte differentiation
Daniel Larocque, André Galarneau, Hsueh-Ning Liu, Michelle Scott, Guillermina Almazan and Stéphane Richard
Nature Neuroscience 8, 27–33
(January 2005); doi:10.1038/nn1359
| Abstract | Full Text (HTML/PDF) |
brief communication
Odorant receptor heterodimerization in the olfactory system of Drosophila melanogaster
Eva M Neuhaus, Günter Gisselmann, Weiyi Zhang, Ruth Dooley, Klemens Störtkuhl and Hanns Hatt
Nature Neuroscience 8, 15–17
(January 2005); doi:10.1038/nn1371
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review article
Modulation of neurodegeneration by molecular chaperones
Paul J. Muchowski and Jennifer L. Wacker
Nature Reviews Neuroscience 6, 11–22
(January 2005); doi:10.1038/nrn1587
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review article
Psoriasis: emerging therapeutic strategies
Alice B. Gottlieb
Nature Reviews Drug Discovery 4, 19–34
(January 2005); doi:10.1038/nrd1607
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article
Using protein-DNA chimeras to detect and count small numbers of molecules
Ian Burbulis, Kumiko Yamaguchi, Andrew Gordon, Robert Carlson and Roger Brent
Nature Methods 2, 31–37
(January 2005); doi:10.1038/nmeth729
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news and views
Tadpoles by the tail
Garry P Nolan
Nature Methods 2, 11–12
(January 2005); doi:10.1038/nmeth0105-11
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article
The invertor knock-in conditional chromosomal translocation mimic
Alan Forster, Richard Pannell, Lesley F Drynan, Rosalind Codrington, Angelika Daser, Markus Metzler, M Natividad Lobato and Terence H Rabbitts
Nature Methods 2, 27–30
(January 2005); doi:10.1038/nmeth727
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