The Research Library categorizes, and provides access to, all recent signaling-related research published in the Nature Publishing Group journals. The selection is deliberately broad to facilitate access to all research impacting on the signaling community. Both primary research and review articles are included, as are 'News and Views' articles.
Click here for free access to the 'Featured Articles' section, with new articles every week.
letter Phosphoinositide phosphatase activity coupled to an intrinsic voltage sensor
Yoshimichi Murata, Hirohide Iwasaki, Mari Sasaki, Kazuo Inaba and Yasushi Okamura Nature435, 1239–1243
(30 June 2005); doi:10.1038/nature03650
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letter Ephrin signalling controls brain size by regulating apoptosis of neural progenitors
Vanessa Depaepe, Nathalie Suarez-Gonzalez, Audrey Dufour, Lara Passante, Jessica A Gorski, Kevin R. Jones, Catherine Ledent and Pierre Vanderhaeghen Nature435, 1244–1250
(30 June 2005); doi:10.1038/nature03651
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letter Auxin inhibits endocytosis and promotes its own efflux from cells
Tomasz Paciorek, Eva Zazímalová, Nadia Ruthardt, Jan Petrášek, York-Dieter Stierhof, Jürgen Kleine-Vehn, David A. Morris, Neil Emans, Gerd Jürgens, Niko Geldner and Jirí Friml Nature435, 1251–1256
(30 June 2005); doi:10.1038/nature03633
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letter The conserved protein DCN-1/Dcn1p is required for cullin neddylation in C. elegans and S. cerevisiae
Thimo Kurz, Nurhan Özlü, Fabian Rudolf, Sean M. O'Rourke, Brian Luke, Kay Hofmann, Anthony A. Hyman, Bruce Bowerman and Matthias Peter Nature435, 1257–1261
(30 June 2005); doi:10.1038/nature03662
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letter RNA-interference-directed chromatin modification coupled to RNA polymerase II transcription
Vera Schramke, Daniel M. Sheedy, Ahmet M. Denli, Carolina Bonila, Karl Ekwall, Gregory J. Hannon and Robin C. Allshire Nature435, 1275–1279
(30 June 2005); doi:10.1038/nature03652
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news and views Gene regulation: Expression and silencing coupled
Stephen Buratowski and Danesh Moazed Nature435, 1174–1175
(30 June 2005); doi:10.1038/4351174b
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letter Argonaute 2/RISC resides in sites of mammalian mRNA decay known as cytoplasmic bodies
George L. Sen and Helen M. Blau Nature Cell Biology7, 633–636
(June 2005); doi:10.1038/ncb1265
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news and views Transcription RINGs in repair
Mary Ann Osley Nature Cell Biology7, 553–555
(June 2005); doi:10.1038/ncb0605-553
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article Recruitment of adult thymic progenitors is regulated by P-selectin and its ligand PSGL-1
Fabio M V Rossi, Stephane Y Corbel, Jasmeen S Merzaban, Douglas A Carlow, Klaus Gossens, Jeffrey Duenas, Leslie So, Lin Yi and Hermann J Ziltener Nature Immunology6, 626–634
(June 2005); doi:10.1038/ni1203
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review article Negative regulation of Toll-like receptor-mediated immune responses
Foo Y. Liew, Damo Xu, Elizabeth K. Brint and Luke A. J. O'Neill Nature Reviews Immunology5, 446–458
(June 2005); doi:10.1038/nri1630
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article Stat3 is required for ALK-mediated lymphomagenesis and provides a possible therapeutic target
Roberto Chiarle, William J Simmons, Honjying Cai, Girish Dhall, Alberto Zamo, Regina Raz, James G Karras, David E Levy and Giorgio Inghirami Nature Medicine11, 623–629
(June 2005); doi:10.1038/nm1249
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news and views Validating Stat3 in cancer therapy
James E Darnell Jr Nature Medicine11, 595–596
(June 2005); doi:10.1038/nm0605-595
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article Reversible blockade of experience-dependent plasticity by calcineurin in mouse visual cortex
Yupeng Yang, Quentin S Fischer, Ying Zhang, Karsten Baumgärtel, Isabelle M Mansuy and Nigel W Daw Nature Neuroscience8, 791–796
(June 2005); doi:10.1038/nn1464
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research article Rapid generation of specific antibodies by enhanced homologous recombination
Hidetaka Seo, Mieko Masuoka, Hiromu Murofushi, Shunichi Takeda, Takehiko Shibata and Kunihiro Ohta Nature Biotechnology23, 731–735
(June 2005); doi:10.1038/nbt1092
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research article Intein-based biosynthetic incorporation of unlabeled protein tags into isotopically labeled proteins for NMR studies
Sara Züger and Hideo Iwai Nature Biotechnology23, 736–740
(June 2005); doi:10.1038/nbt1097
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article Signaling conformations of the tall cytokine receptor gp130 when in complex with IL-6 and IL-6 receptor
Georgios Skiniotis, Martin J Boulanger, K Christopher Garcia and Thomas Walz Nature Structural and Molecular Biology12, 545–551
(June 2005); doi:10.1038/nsmb941
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news and views Bow to your partner for signaling
Heike M Hermanns, Gerhard Müller-Newen, Peter C Heinrich and Serge Haan Nature Structural and Molecular Biology12, 476–478
(June 2005); doi:10.1038/nsmb0605-476
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article A Tn7-based broad-range bacterial cloning and expression system
Kyoung-Hee Choi, Jared B Gaynor, Kimberly G White, Carolina Lopez, Catharine M Bosio, RoxAnn R Karkhoff-Schweizer and Herbert P Schweizer Nature Methods2, 443–448
(June 2005); doi:10.1038/nmeth765
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article Calmodulin-dependent protein kinase IV regulates nuclear export of Cabin1 during T-cell activation
Fan Pan, Anthony R Means and Jun O Liu The EMBO Journal24, 2104–2113
(June 2005); doi:10.1038/sj.emboj.7600685
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article Stargazin modulates AMPA receptor gating and trafficking by distinct domains
Susumu Tomita, Hillel Adesnik, Masayuki Sekiguchi, Wei Zhang, Keiji Wada, James R. Howe, Roger A. Nicoll and David S. Bredt Nature435, 1052–1058
(23 June 2005); doi:10.1038/nature03624
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news and views Neuroscience: An intrusive chaperone
Anders S. Kristensen and Stephen F. Traynelis Nature435, 1042–1043
(23 June 2005); doi:10.1038/4351042a
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letter EphB receptor activity suppresses colorectal cancer progression
Eduard Batlle , Julinor Bacani, Harry Begthel, Suzanne Jonkeer, Alexander Gregorieff, Maaike van de Born, Núria Malats, Elena Sancho, Elles Boon, Tony Pawson, Steven Gallinger, Steven Pals and Hans Clevers Nature435, 1126–1130
(23 June 2005); doi:10.1038/nature03626
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letter Crm1 is a mitotic effector of Ran-GTP in somatic cells
Alexei Arnaoutov, Yoshiaki Azuma, Katharina Ribbeck, Jomon Joseph, Yekaterina Boyarchuk, Tatiana Karpova, James McNally and Mary Dasso Nature Cell Biology7, 626–632
(June 2005); doi:10.1038/ncb1263
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news and views The Crm de la crème of mitosis
Paul R. Clarke Nature Cell Biology7, 551–552
(June 2005); doi:10.1038/ncb0605-551
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article CD14 is required for MyD88-independent LPS signaling
Zhengfan Jiang, Philippe Georgel, Xin Du, Louis Shamel, Sosathya Sovath, Suzanne Mudd, Michael Huber, Christoph Kalis, Simone Keck, Chris Galanos, Marina Freudenberg and Bruce Beutler Nature Immunology6, 565–570
(June 2005); doi:10.1038/ni1207
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news and views A smooth operator for LPS responses
Paul J Godowski Nature Immunology6, 544–546
(June 2005); doi:10.1038/ni0605-544
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review article NFAT proteins: key regulators of T-cell development and function
Fernando Macian Nature Reviews Immunology5, 472–484
(June 2005); doi:10.1038/nri1632
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letter Reversing systemic inflammatory response syndrome with chemokine receptor pepducins
Nicole C Kaneider, Anika Agarwal, Andrew J Leger and Athan Kuliopulos Nature Medicine11, 661–665
(June 2005); doi:10.1038/nm1245
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news and views Gateway to the metabolic syndrome
Gema Medina-Gomez and Antonio Vidal-Puig Nature Medicine11, 602–603
(June 2005); doi:10.1038/nm0605-602
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article ATP mediates rapid microglial response to local brain injury in vivo
Dimitrios Davalos, Jaime Grutzendler, Guang Yang, Jiyun V Kim, Yi Zuo, Steffen Jung, Dan R Littman, Michael L Dustin and Wen-Biao Gan Nature Neuroscience8, 752–758
(June 2005); doi:10.1038/nn1472
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news and views Brain's guard cells show their agility Nature Neuroscience8, 707
(June 2005); doi:10.1038/nn0605-707
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review article Integration of biochemical signalling in spines
Mary B. Kennedy, Holly C. Beale, Holly J. Carlisle and Lorraine R. Washburn Nature Reviews Neuroscience6, 423–434
(June 2005); doi:10.1038/nrn1685
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research article Antibody mediated in vivo delivery of small interfering RNAs via cell-surface receptors
Erwei Song, Pengcheng Zhu, Sang-Kyung Lee, Dipanjan Chowdhury, Steven Kussman, Derek M Dykxhoorn, Yi Feng, Deborah Palliser, David B Weiner, Premlata Shankar, Wayne A Marasco and Judy Lieberman Nature Biotechnology23, 709–717
(June 2005); doi:10.1038/nbt1101
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news and views Viral-mediated plant transformation gets a boost
Stanton B Gelvin Nature Biotechnology23, 684–685
(June 2005); doi:10.1038/nbt0605-684
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article Versatile modes of peptide recognition by the AAA+ adaptor protein SspB
Igor Levchenko, Robert A Grant, Julia M Flynn, Robert T Sauer and Tania A Baker Nature Structural and Molecular Biology12, 520–525
(June 2005); doi:10.1038/nsmb934
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article Internal structure and visualization of transmembrane domains of the RyR1 calcium release channel by cryo-EM
Montserrat Samsó, Terence Wagenknecht and P D Allen Nature Structural and Molecular Biology12, 539–544
(June 2005); doi:10.1038/nsmb938
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article A second-site suppressor strategy for chemical genetic analysis of diverse protein kinases
Chao Zhang, Denise M Kenski, Jennifer L Paulson, Arale Bonshtien, Guido Sessa, Janet V Cross, Dennis J Templeton and Kevan M Shokat
Nature Methods2, 435–441
(June 2005); doi:10.1038/nmeth764
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news and views Kinase chemical genomics — a new rule for the exceptions
Benjamin F Cravatt Nature Methods2, 411–412
(June 2005); doi:10.1038/nmeth0605-411
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letter Notch/γ-secretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cells
Johan H. van Es, Marielle E. van Gijn, Orbicia Riccio, Maaike van den Born, Marc Vooijs, Harry Begthel, Miranda Cozijnsen, Sylvie Robine, Doug J. Winton, Freddy Radtke and Hans Clevers Nature435, 959–963
(16 June 2005); doi:10.1038/nature03659
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letter Notch signals control the fate of immature progenitor cells in the intestine
Silvia Fre, Mathilde Huyghe, Philippos Mourikis, Sylvie Robine, Daniel Louvard and Spyros Artavanis-Tsakonas Nature435, 964–968
(16 June 2005); doi:10.1038/nature03589
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letter Stem cell division is regulated by the microRNA pathway S. D. Hatfield, H. R. Shcherbata, K. A. Fischer, K. Nakahara, R. W. Carthew and H. Ruohola-Baker Nature435, 974–978
(16 June 2005); doi:10.1038/nature03816
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article Caenorhabditis elegans RME-6 is a novel regulator of RAB-5 at the clathrin-coated pit
Miyuki Sato, Ken Sato, Paul Fonarev, Chih-Jen Huang, Willisa Liou and Barth D. Grant Nature Cell Biology7, 559–569
(June 2005); doi:10.1038/ncb1261
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news and views A sixth sense for Rab5
Alexander M. van der Bliek Nature Cell Biology7, 548–550
(June 2005); doi:10.1038/ncb0605-548
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letter The Diaphanous-related formin dDia2 is required for the formation and maintenance of filopodia
Antje Schirenbeck, Till Bretschneider, Rajesh Arasada, Michael Schleicher and Jan Faix Nature Cell Biology7, 619–625
(June 2005); doi:10.1038/ncb1266
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review article Developmental Cell Biology: Eph receptor signalling casts a wide net on cell behaviour
Elena B. Pasquale Nature Reviews Molecular Cell Biology6, 462–475
(June 2005); doi:10.1038/nrm1662
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article ROS-dependent activation of the TRAF6-ASK1-p38 pathway is selectively required for TLR4-mediated innate immunity
Atsushi Matsuzawa, Kaoru Saegusa, Takuya Noguchi, Chiharu Sadamitsu, Hideki Nishitoh, Shigenori Nagai, Shigeo Koyasu, Kunihiro Matsumoto, Kohsuke Takeda and Hidenori Ichijo Nature Immunology6, 587–592
(June 2005); doi:10.1038/ni1200
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news and views Linking stress to immunity?
Bing Su Nature Immunology6, 541–542
(June 2005); doi:10.1038/ni0605-541
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review article Recognition of lipid antigens by T cells
Gennaro De Libero and Lucia Mori Nature Reviews Immunology5, 485–496
(June 2005); doi:10.1038/nri1631
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letter Inflammatory arthritis requires Foxo3a to prevent Fas ligand-induced neutrophil apoptosis
Helena Jonsson, Paul Allen and Stanford L Peng Nature Medicine11, 666–671
(June 2005); doi:10.1038/nm1248
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news and views A fork in the pathway to inflammation and arthritis
Foo Y Liew and Iain B McInnes Nature Medicine11, 601–602
(June 2005); doi:10.1038/nm0605-601
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review article Disrupting tumour blood vessels
Gillian M. Tozer, Chryso Kanthou and Bruce C. Baguley Nature Reviews Cancer5, 423–435
(June 2005); doi:10.1038/nrc1628
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article LINGO-1 negatively regulates myelination by oligodendrocytes
Sha Mi, Robert H Miller, Xinhua Lee, Martin L Scott, Svetlane Shulag-Morskaya, Zhaohui Shao, Jufang Chang, Greg Thill, Melissa Levesque, Mingdi Zhang, Cathy Hession, Dinah Sah, Bruce Trapp, Zhigang He, Vincent Jung, John M McCoy and R Blake Pepinsky Nature Neuroscience8, 745–751
(June 2005); doi:10.1038/nn1460
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research article A molecular ruler based on plasmon coupling of single gold and silver nanoparticles
Carsten Sönnichsen, Björn M Reinhard, Jan Liphardt and A Paul Alivisatos Nature Biotechnology23, 741–745
(June 2005); doi:10.1038/nbt1100
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news and views Plasmon coupling measures up
C Shad Thaxton and Chad A Mirkin Nature Biotechnology23, 681–682
(June 2005); doi:10.1038/nbt0605-681
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research article Characterization and culture of human embryonic stem cells
Lisa M Hoffman and Melissa K Carpenter Nature Biotechnology23, 699–708
(June 2005); doi:10.1038/nbt1102
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article A newly discovered function for RNase L in regulating translation termination
Florence Le Roy, Tamim Salehzada, Catherine Bisbal, Joseph P Dougherty and Stuart W Peltz Nature Structural and Molecular Biology12, 505–512
(June 2005); doi:10.1038/nsmb944
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news and views The end justifies the means
Allan Jacobson Nature Structural and Molecular Biology12, 474–475
(June 2005); doi:10.1038/nsmb0605-474
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brief communication An inducible translocation strategy to rapidly activate and inhibit small GTPase signaling pathways
Takanari Inoue, Won Do Heo, Joshua S Grimley, Thomas J Wandless and Tobias Meyer Nature Methods2, 415–418
(June 2005); doi:10.1038/nmeth763
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letter A microRNA polycistron as a potential human oncogene
Lin He, J. Michael Thomson, Michael T. Hemann, Eva Hernando-Monge, David Mu, Summer Goodson, Scott Powers, Carlos Cordon-Cardo, Scott W. Lowe, Gregory J. Hannon and Scott M. Hammond Nature435, 828–833
(09 June 2005); doi:10.1038/nature03552
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letter MicroRNA expression profiles classify human cancers
Jun Lu , Gad Getz, Eric A. Miska , Ezequiel Alvarez-Saavedra, Justin Lamb, David Peck, Alejandro Sweet-Cordero, Benjamin L. Ebert, Raymond H. Mak, Adolfo A. Ferrando, James R. Downing, Tyler Jacks, H. Robert Horvitz and Todd R. Golub Nature435, 834–838
(09 June 2005); doi:10.1038/nature03702
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letter c-Myc-regulated microRNAs modulate E2F1 expression
Kathryn A. O'Donnell, Erik A. Wentzel, Karen I. Zeller, Chi V. Dang and Joshua T. Mendell Nature435, 839–843
(09 June 2005); doi:10.1038/nature03677
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news and views Cancer genomics: Small RNAs with big impacts
Paul S. Meltzer Nature435, 745–746
(09 June 2005); doi:10.1038/435745a
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article Prediction of preadipocyte differentiation by gene expression reveals role of insulin receptor substrates and necdin
Yu-Hua Tseng, Atul J. Butte, Efi Kokkotou, Vijay K. Yechoor, Cullen M. Taniguchi, Kristina M. Kriauciunas, Aaron M. Cypess, Michio Niinobe, Kazuaki Yoshikawa, Mary Elizabeth Patti and C. Ronald Kahn Nature Cell Biology7, 601–611
(June 2005); doi:10.1038/ncb1259
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news and views Fickle factor foils fat fate
Ormond A. MacDougald and Charles F. Burant Nature Cell Biology7, 543–545
(June 2005); doi:10.1038/ncb0605-543
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review article Annexins: linking Ca2+ signalling to membrane dynamics
Volker Gerke, Carl E. Creutz and Stephen E. Moss Nature Reviews Molecular Cell Biology6, 449–461
(June 2005); doi:10.1038/nrm1661
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article Dynamic recruitment of PAK1 to the immunological synapse is mediated by PIX independently of SLP-76 and Vav1
Hyewon Phee, Robert T Abraham and Arthur Weiss Nature Immunology6, 608–617
(June 2005); doi:10.1038/ni1199
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article Negative regulation of Toll-like receptor 4 signaling by the Toll-like receptor homolog RP105
Senad Divanovic, Aurelien Trompette, Sowsan F Atabani, Rajat Madan, Douglas T Golenbock, Alberto Visintin, Robert W Finberg, Alexander Tarakhovsky, Stefanie N Vogel, Yasmine Belkaid, Evelyn A Kurt-Jones and Christopher L Karp Nature Immunology6, 571–578
(June 2005); doi:10.1038/ni1198
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review article Mammalian defensins in the antimicrobial immune response
Michael E Selsted and Andre J Ouellette Nature Immunology6, 551–557
(June 2005); doi:10.1038/ni1206
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review article Transcriptional networks in developing and mature B cells
Patrick Matthias and Antonius G. Rolink Nature Reviews Immunology5, 497–508
(June 2005); doi:10.1038/nri1633
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article TLR activation triggers the rapid differentiation of monocytes into macrophages and dendritic cells
Stephan R Krutzik, Belinda Tan, Huiying Li, Maria Teresa Ochoa, Philip T Liu, Sarah E Sharfstein, Thomas G Graeber, Peter A Sieling, Yong-Jun Liu, Thomas H Rea, Barry R Bloom and Robert L Modlin Nature Medicine11, 653–660
(June 2005); doi:10.1038/nm1246
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article Epistasis between mouse Klra and major histocompatibility complex class I loci is associated with a new mechanism of natural killer cell-mediated innate resistance to cytomegalovirus infection
Marie-Pierre Desrosiers, Agnieszka Kielczewska, J-C Loredo-Osti, Sonia Girard Adam, Andrew P Makrigiannis, Suzanne Lemieux, Trung Pham, Melissa B Lodoen, Kenneth Morgan, Lewis L Lanier and Silvia M Vidal Nature Genetics37, 593–599
(June 2005); doi:10.1038/ng1564
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news and views Antiviral synergism
Mary Carrington Nature Genetics37, 565–566
(June 2005); doi:10.1038/ng0605-565
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article XTRPC1-dependent chemotropic guidance of neuronal growth cones
Sangwoo Shim, Eyleen L Goh, Shaoyu Ge, Kurt Sailor, Joseph P Yuan, H Llewelyn Roderick, Martin D Bootman, Paul F Worley, Hongjun Song and Guo-li Ming Nature Neuroscience8, 730–735
(June 2005); doi:10.1038/nn1459
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brief communication Laminin stimulates and guides axonal outgrowth via growth cone myosin II activity
Stephen G Turney and Paul C Bridgman Nature Neuroscience8, 717–719
(June 2005); doi:10.1038/nn1466
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review article Glycans in cancer and inflammation — potential for therapeutics and diagnostics
Danielle H. Dube and Carolyn R. Bertozzi Nature Reviews Drug Discovery4, 477–488
(June 2005); doi:10.1038/nrd1751
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article The Hsp70 Ssz1 modulates the function of the ribosome-associated J-protein Zuo1
Peggy Huang, Matthias Gautschi, William Walter, Sabine Rospert and Elizabeth A Craig Nature Structural and Molecular Biology12, 497–504
(June 2005); doi:10.1038/nsmb942
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news and views Ribosomes catch Hsp70s
Bernd Bukau Nature Structural and Molecular Biology12, 472–473
(June 2005); doi:10.1038/nsmb0605-472
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article Solution structure of the HIV-1 integrase-binding domain in LEDGF/p75
Peter Cherepanov, Zhen-Yu J Sun, Shaila Rahman, Goedele Maertens, Gerhard Wagner and Alan Engelman Nature Structural and Molecular Biology12, 526–532
(June 2005); doi:10.1038/nsmb937
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research article Systemic Agrobacterium tumefaciens-mediated transfection of viral replicons for efficient transient expression in plants
Sylvestre Marillonnet, Carola Thoeringer, Romy Kandzia, Victor Klimyuk and Yuri Gleba Nature Biotechnology23, 718–723
(June 2005); doi:10.1038/nbt1094
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news and views Viral-mediated plant transformation gets a boost
Stanton B Gelvin Nature Biotechnology23, 684–685
(June 2005); doi:10.1038/nbt0605-684
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research article A high-throughput assay for assessing the cell permeability of combinatorial libraries
Peng Yu, Bo Liu and Thomas Kodadek Nature Biotechnology23, 746–751
(June 2005); doi:10.1038/nbt1099
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article Highly efficient molecular delivery into mammalian cells using carbon nanotube spearing
Dong Cai, Jennifer M Mataraza, Zheng-Hong Qin, Zhongping Huang, Jianyu Huang, Thomas C Chiles, David Carnahan, Kris Kempa and Zhifeng Ren Nature Methods2, 449–454
(June 2005); doi:10.1038/nmeth761
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letter An inhibitor of Bcl-2 family proteins induces regression of solid tumours
Tilman Oltersdorf , Steven W. Elmore , Alexander R. Shoemaker , Robert C. Armstrong , David J. Augeri , Barbara A. Belli , Milan Bruncko , Thomas L. Deckwerth , Jurgen Dinges , Philip J. Hajduk , Mary K. Joseph , Shinichi Kitada , Stanley J. Korsmeyer , Aaron R. Kunzer , Anthony Letai , Chi Li , Michael J. Mitten , David G. Nettesheim , ShiChung Ng , Paul M. Nimmer , Jacqueline M. O'Connor , Anatol Oleksijew , Andrew M. Petros , John C. Reed , Wang Shen , Stephen K. Tahir , Craig B. Thompson , Kevin J. Tomaselli , Baole Wang , Michael D. Wendt , Haichao Zhang , Stephen W. Fesik and Saul H. Rosenberg Nature435, 677–681
(02 June 2005); doi:10.1038/nature03579
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letter Insights into E3 ligase activity revealed by a SUMO-RanGAP1-Ubc9-Nup358 complex
David Reverter and Christopher D. Lima Nature435, 687–692
(02 June 2005); doi:10.1038/nature03588
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article Microtubule-induced focal adhesion disassembly is mediated by dynamin and focal adhesion kinase
Ellen J. Ezratty, Michael A. Partridge and Gregg G. Gundersen Nature Cell Biology7, 581–590
(June 2005); doi:10.1038/ncb1262
| Abstract | Full Text (HTML/PDF) |
news and views Foot in mouth: do focal adhesions disassemble by endocytosis?
Keith Burridge Nature Cell Biology7, 545–547
(June 2005); doi:10.1038/ncb0605-545
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article Sensitized RNAi screen of human kinases and phosphatases identifies new regulators of apoptosis and chemoresistance
Jeffrey P. MacKeigan, Leon O. Murphy and John Blenis Nature Cell Biology7, 591–600
(June 2005); doi:10.1038/ncb1258
| Abstract | Full Text (HTML/PDF) |
review article Autophagy in metazoans: cell survival in the land of plenty
Julian J. Lum, Ralph J. DeBerardinis and Craig B. Thompson Nature Reviews Molecular Cell Biology6, 439–448
(June 2005); doi:10.1038/nrm1660
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article Enhanced Toll-like receptor responses in the absence of signaling adaptor DAP12
Jessica A Hamerman, Nadia K Tchao, Clifford A Lowell and Lewis L Lanier Nature Immunology6, 579–586
(June 2005); doi:10.1038/ni1204
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article Transforming growth factor-β controls T helper type 1 cell development through regulation of natural killer cell interferon-γ
Yasmina Laouar, Fayyaz S Sutterwala, Leonid Gorelik and Richard A Flavell Nature Immunology6, 600–607
(June 2005); doi:10.1038/ni1197
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review article Control of lymphocyte development by nuclear factor-κB
Ulrich Siebenlist, Keith Brown and Estefania Claudio Nature Reviews Immunology5, 435–445
(June 2005); doi:10.1038/nri1629
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brief communication A screen of the complete protein kinase gene family identifies diverse patterns of somatic mutations in human breast cancer
Philip Stephens, Sarah Edkins, Helen Davies, Chris Greenman, Charles Cox, Chris Hunter, Graham Bignell, Jon Teague, Raffaella Smith, Claire Stevens, Sarah O'Meara, Adrian Parker, Patrick Tarpey, Tim Avis, Andy Barthorpe, Lisa Brackenbury, Gemma Buck, Adam Butler, Jody Clements, Jennifer Cole, Ed Dicks, Ken Edwards, Simon Forbes, Matthew Gorton, Kristian Gray, Kelly Halliday, Rachel Harrison, Katy Hills, Jonathon Hinton, David Jones, Vivienne Kosmidou, Ross Laman, Richard Lugg, Andrew Menzies, Janet Perry, Robert Petty, Keiran Raine, Rebecca Shepherd, Alexandra Small, Helen Solomon, Yvonne Stephens, Calli Tofts, Jennifer Varian, Anthony Webb, Sofie West, Sara Widaa, Andrew Yates, Francis Brasseur, Colin S Cooper, Adrienne M Flanagan, Anthony Green, Maggie Knowles, Suet Y Leung, Leendert H J Looijenga, Bruce Malkowicz, Marco A Pierotti, Bin Teh, Siu T Yuen, Andrew G Nicholson, Sunil Lakhani, Douglas F Easton, Barbara L Weber, Michael R Stratton, P Andrew Futreal and Richard Wooster Nature Genetics37, 590–592
(June 2005); doi:10.1038/ng1571
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analysis Mining for regulatory programs in the cancer transcriptome
Daniel R Rhodes, Shanker Kalyana-Sundaram, Vasudeva Mahavisno, Terrence R Barrette, Debashis Ghosh and Arul M Chinnaiyan Nature Genetics37, 579–583
(June 2005); doi:10.1038/ng1578
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review article Miniaturization in functional genomics and proteomics
Sascha Sauer, Bodo M. H. Lange, Johan Gobom, Lajos Nyarsik, Harald Seitz and Hans Lehrach Nature Reviews Genetics6, 465–476
(June 2005); doi:10.1038/nrg1618
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article RNA editing produces glycine receptor α3P185L, resulting in high agonist potency
Jochen C Meier, Christian Henneberger, Igor Melnick, Claudia Racca, Robert J Harvey, Uwe Heinemann, Volker Schmieden and Rosemarie Grantyn Nature Neuroscience8, 736–744
(June 2005); doi:10.1038/nn1467
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article SRF mediates activity-induced gene expression and synaptic plasticity but not neuronal viability
Narendrakumar Ramanan, Ying Shen, Sarah Sarsfield, Thomas Lemberger, Günther Schütz, David J Linden and David D Ginty Nature Neuroscience8, 759–767
(June 2005); doi:10.1038/nn1462
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article Endocannabinoid signaling depends on the spatial pattern of synapse activation
Païkan Marcaggi and David Attwell Nature Neuroscience8, 776–781
(June 2005); doi:10.1038/nn1458
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review article Notch signaling in the mammalian central nervous system: insights from mouse mutants
Keejung Yoon and Nicholas Gaiano Nature Neuroscience8, 709–715
(June 2005); doi:10.1038/nn1475
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article The RISC subunit Tudor-SN binds to hyper-edited double-stranded RNA and promotes its cleavage
A D J Scadden Nature Structural and Molecular Biology12, 489–496
(June 2005); doi:10.1038/nsmb936
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brief communication Crystal structure of a mutant mineralocorticoid receptor responsible for hypertension
Jérôme Fagart, Jessica Huyet, Grégory M Pinon, Marina Rochel, Claudine Mayer and Marie-Edith Rafestin-Oblin Nature Structural and Molecular Biology12, 554–555
(June 2005); doi:10.1038/nsmb939
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review article Process or perish: quality control in mRNA biogenesis
Milo B Fasken and Anita H Corbett Nature Structural and Molecular Biology12, 482–488
(June 2005); doi:10.1038/nsmb945
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article Reverse MAPPIT: screening for protein-protein interaction modifiers in mammalian cells
Sven Eyckerman, Irma Lemmens, Dominiek Catteeuw, Annick Verhee, Joel Vandekerckhove, Sam Lievens and Jan Tavernier Nature Methods2, 427–433
(June 2005); doi:10.1038/nmeth760
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news and views Perturbing interactions
Stuart Milstein and Marc Vidal Nature Methods2, 412–414
(June 2005); doi:10.1038/nmeth0605-412
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