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Research library: browse by date

July 2005

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The Research Library categorizes, and provides access to, all recent signaling-related research published in the Nature Publishing Group journals. The selection is deliberately broad to facilitate access to all research impacting on the signaling community. Both primary research and review articles are included, as are 'News and Views' articles.

Click here for free access to the 'Featured Articles' section, with new articles every week.

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article
Systematic analysis of genes required for synapse structure and function
Derek Sieburth, QueeLim Ch'ng, Michael Dybbs, Masoud Tavazoie, Scott Kennedy, Duo Wang, Denis Dupuy, Jean-François Rual, David E. Hill, Marc Vidal, Gary Ruvkun and Joshua M. Kaplan
Nature 436, 510–517
(28 July 2005); doi:10.1038/nature03809
| Abstract | Full Text (HTML / PDF) |

article
Genes that mediate breast cancer metastasis to lung
Andy J. Minn , Gaorav P. Gupta, Peter M. Siegel, Paula D. Bos, Weiping Shu, Dilip D. Giri, Agnes Viale, Adam B. Olshen, William L. Gerald and Joan Massagué
Nature 436, 518–524
(28 July 2005); doi:10.1038/nature03799
| Abstract | Full Text (HTML / PDF) |

letter
Somatic control of germline sexual development is mediated by the JAK/STAT pathway
Matthew Wawersik, Allison Milutinovich, Abbie L. Casper, Erika Matunis, Brian Williams and Mark Van Doren
Nature 436, 563–567
(28 July 2005); doi:10.1038/nature03849
| First Paragraph | Full Text (HTML / PDF) |

news and views
Cancer: One step at a time
David Mooney
Nature 436, 468–469
(28 July 2005); doi:10.1038/436468a
| Full Text (HTML / PDF) |

news and views
Neuroscience: Genomics reaches the synapse
Cori Bargmann
Nature 436, 473–474
(28 July 2005); doi:10.1038/436473a
| Full Text (HTML / PDF) |

letter
MicroRNA-dependent localization of targeted mRNAs to mammalian P-bodies
Jidong Liu, Marco Antonio Valencia-Sanchez, Gregory J. Hannon and Roy Parker
Nature Cell Biology 7, 719–723
(July 2005); doi:10.1038/ncb1274
| First Paragraph | Full Text (HTML/PDF) |

news and views
RNAi and the P-body connection
John J. Rossi
Nature Cell Biology 7, 643–644
(July 2005); doi:10.1038/ncb0705-643
| Full Text (HTML/PDF) |

review article
Plants, symbiosis and parasites: a calcium signalling connection
Jeffrey F. Harper and Alice Harmon
Nature Reviews Molecular Cell Biology 6, 555–566
(July 2005); doi:10.1038/nrm1679
| Abstract | Full Text (HTML / PDF) |

article
A critical function for type I interferons in cancer immunoediting
Gavin P Dunn, Allen T Bruce, Kathleen C F Sheehan, Vijay Shankaran, Ravindra Uppaluri, Jack D Bui, Mark S Diamond, Catherine M Koebel, Cora Arthur, J Michael White and Robert D Schreiber
Nature Immunology 6, 722–729
(July 2005); doi:10.1038/ni1213
| Abstract | Full Text (HTML/PDF) |

news and views
Type I interferon and cancer immunoediting
Mark J Smyth
Nature Immunology 6, 646–648
(July 2005); doi:10.1038/ni0705-646
| Full Text (HTML/PDF) |

review article
Sphingosine 1-phosphate and its receptors: an autocrine and paracrine network
Hugh Rosen and Edward J. Goetzl
Nature Reviews Immunology 5, 560–570
(July 2005); doi:10.1038/nri1650
| Abstract | Full Text (HTML / PDF) |

article
Lack of the architectural factor HMGA1 causes insulin resistance and diabetes in humans and mice
Daniela Foti, Eusebio Chiefari, Monica Fedele, Rodolfo Iuliano, Leonardo Brunetti, Francesco Paonessa, Guidalberto Manfioletti, Fabrizio Barbetti, Arturo Brunetti, Carlo M Croce, Alfredo Fusco and Antonio Brunetti
Nature Medicine 11, 765–773
(July 2005); doi:10.1038/nm1254
| Abstract | Full Text (HTML/PDF) |

letter
Use of human tissue to assess the oncogenic activity of melanoma-associated mutations
Yakov Chudnovsky, Amy E Adams, Paul B Robbins, Qun Lin and Paul A Khavari
Nature Genetics 37, 745–749
(July 2005); doi:10.1038/ng1586
| First Paragraph | Full Text (HTML/PDF) |

letter
Dynein mutations impair autophagic clearance of aggregate-prone proteins
Brinda Ravikumar, Abraham Acevedo-Arozena, Sara Imarisio, Zdenek Berger, Coralie Vacher, Cahir J O'Kane, Steve D M Brown and David C Rubinsztein
Nature Genetics 37, 771–776
(July 2005); doi:10.1038/ng1591
| First Paragraph | Full Text (HTML/PDF) |

article
PI3 kinase signaling is required for retrieval and extinction of contextual memory
Xi Chen, Michael G Garelick, Hongbing Wang, Vicky Li, Jaime Athos and Daniel R Storm
Nature Neuroscience 8, 925–931
(July 2005); doi:10.1038/nn1482
| Abstract | Full Text (HTML/PDF) |

review article
Neurosteroids: endogenous regulators of the GABAA receptor
Delia Belelli and Jeremy J. Lambert
Nature Reviews Neuroscience 6, 565–575
(July 2005); doi:10.1038/nrn1703
| Abstract | Full Text (HTML / PDF) |

review article
Design and development of polymers for gene delivery
Daniel W. Pack, Allan S. Hoffman, Suzie Pun and Patrick S. Stayton
Nature Reviews Drug Discovery 4, 581–593
(July 2005); doi:10.1038/nrd1775
| Abstract | Full Text (HTML / PDF) |

article
Serum retinol binding protein 4 contributes to insulin resistance in obesity and type 2 diabetes
Qin Yang, Timothy E. Graham, Nimesh Mody, Frederic Preitner, Odile D. Peroni, Janice M. Zabolotny, Ko Kotani, Loredana Quadro and Barbara B. Kahn
Nature 436, 356–362
(21 July 2005); doi:10.1038/nature03711
| Abstract | Full Text (HTML / PDF) |

letter
Male-specific fruitless specifies the neural substrates of Drosophila courtship behaviour
Devanand S. Manoli, Margit Foss, Adriana Villella, Barbara J. Taylor, Jeffrey C. Hall and Bruce S. Baker
Nature 436, 395–400
(21 July 2005); doi:10.1038/nature03859
| First Paragraph | Full Text (HTML / PDF) |

letter
EphrinB2 is the entry receptor for Nipah virus, an emergent deadly paramyxovirus
Oscar A. Negrete, Ernest L. Levroney, Hector C. Aguilar, Andrea Bertolotti-Ciarlet, Ronen Nazarian, Sara Tajyar and Benhur Lee
Nature 436, 401–405
(21 July 2005); doi:10.1038/nature03838
| First Paragraph | Full Text (HTML / PDF) |

letter
Trans-SNARE pairing can precede a hemifusion intermediate in intracellular membrane fusion
Christoph Reese , Felix Heise and Andreas Mayer
Nature 436, 410–414
(21 July 2005); doi:10.1038/nature03722
| First Paragraph | Full Text (HTML / PDF) |

letter
SUMO-modified PCNA recruits Srs2 to prevent recombination during S phase
Boris Pfander , George-Lucian Moldovan , Meik Sacher , Carsten Hoege and Stefan Jentsch
Nature 436, 428–433
(21 July 2005); doi:10.1038/nature03665
| First Paragraph | Full Text (HTML / PDF) |

letter
DNA processing is not required for ATM-mediated telomere damage response after TRF2 deletion
Giulia B. Celli and Titia de Lange
Nature Cell Biology 7, 712–718
(July 2005); doi:10.1038/ncb1275
| First Paragraph | Full Text (HTML/PDF) |

article
S-nitrosylated GAPDH initiates apoptotic cell death by nuclear translocation following Siah1 binding
Makoto R. Hara, Nishant Agrawal, Sangwon F. Kim, Matthew B. Cascio, Masahiro Fujimuro, Yuji Ozeki, Masaaki Takahashi, Jaime H. Cheah, Stephanie K. Tankou, Lynda D. Hester, Christopher D. Ferris, S. Diane Hayward, Solomon H. Snyder and Akira Sawa
Nature Cell Biology 7, 665–674
(July 2005); doi:10.1038/ncb1268
| Abstract | Full Text (HTML/PDF) |

news and views
A central role for S-nitrosylation in apoptosis
Moran Benhar and Jonathan S. Stamler
Nature Cell Biology 7, 645–646
(July 2005); doi:10.1038/ncb0705-645
| Full Text (HTML/PDF) |

review article
Heparan sulphate proteoglycans: the sweet side of development
Udo Häcker, Kent Nybakken and Norbert Perrimon
Nature Reviews Molecular Cell Biology 6, 530–541
(July 2005); doi:10.1038/nrm1681
| Abstract | Full Text (HTML / PDF) |

article
Notch signaling controls the generation and differentiation of early T lineage progenitors
Arivazhagan Sambandam, Ivan Maillard, Valerie P Zediak, Lanwei Xu, Rachel M Gerstein, Jon C Aster, Warren S Pear and Avinash Bhandoola
Nature Immunology 6, 663–670
(July 2005); doi:10.1038/ni1216
| Abstract | Full Text (HTML/PDF) |

article
Requirement for Notch1 signals at sequential early stages of intrathymic T cell development
Joanne B Tan, Ioana Visan, Julie S Yuan and Cynthia J Guidos
Nature Immunology 6, 671–679
(July 2005); doi:10.1038/ni1217
| Abstract | Full Text (HTML/PDF) |

article
Inhibitors of γ-secretase block in vivo and in vitro T helper type 1 polarization by preventing Notch upregulation of Tbx21
Lisa M Minter, Danielle M Turley, Pritam Das, Hyun Mu Shin, Ila Joshi, Rebecca G Lawlor, Ok Hyun Cho, Tanapat Palaga, Sridevi Gottipati, Janice C Telfer, Lisa Kostura, Abdul H Fauq, Katherine Simpson, Kimberly A Such, Lucio Miele, Todd E Golde, Stephen D Miller and Barbara A Osborne
Nature Immunology 6, 680–688
(July 2005); doi:10.1038/ni1209
| Abstract | Full Text (HTML/PDF) |

news and views
Notch in lymphopoiesis and T cell polarization
Harald von Boehmer
Nature Immunology 6, 641–642
(July 2005); doi:10.1038/ni0705-641
| Full Text (HTML/PDF) |

review article
Intracellular signalling controlling integrin activation in lymphocytes
Tatsuo Kinashi
Nature Reviews Immunology 5, 546–559
(July 2005); doi:10.1038/nri1646
| Abstract | Full Text (HTML / PDF) |

review article
Caspase-independent cell death
Guido Kroemer and Seamus J Martin
Nature Medicine 11, 725–730
(July 2005); doi:10.1038/nm1263
| Abstract | Full Text (HTML/PDF) |

review article
The anaemia of cancer: death by a thousand cuts
Jerry L. Spivak
Nature Reviews Cancer 5, 543–555
(July 2005); doi:10.1038/nrc1648
| Abstract | Full Text (HTML / PDF) |

letter
The roles of MAD1, MAD2 and MAD3 in meiotic progression and the segregation of nonexchange chromosomes
Peter S Cheslock, Benedict J Kemp, Rebecca M Boumil and Dean S Dawson
Nature Genetics 37, 756–760
(July 2005); doi:10.1038/ng1588
| First Paragraph | Full Text (HTML/PDF) |

news and views
A delay like no other
Soni Lacefield and Andrew Murray
Nature Genetics 37, 662–663
(July 2005); doi:10.1038/ng0705-662
| Full Text (HTML/PDF) |

brief communication
Loss of mammalian Sprouty2 leads to enteric neuronal hyperplasia and esophageal achalasia
Takaharu Taketomi, Daigo Yoshiga, Koji Taniguchi, Takashi Kobayashi, Atsushi Nonami, Reiko Kato, Mika Sasaki, Atsuo Sasaki, Hitoshi Ishibashi, Maiko Moriyama, Kei-ichiro Nakamura, Junji Nishimura and Akihiko Yoshimura
Nature Neuroscience 8, 855–857
(July 2005); doi:10.1038/nn1485
| First Paragraph | Full Text (HTML/PDF) |

article
Nonclassical, distinct endocytic signals dictate constitutive and PKC-regulated neurotransmitter transporter internalization
Katherine L Holton, Merewyn K Loder and Haley E Melikian
Nature Neuroscience 8, 881–888
(July 2005); doi:10.1038/nn1478
| Abstract | Full Text (HTML/PDF) |

news and views
Proteomics takes stem cell analyses to another level
Andre Levchenko
Nature Biotechnology 23, 828–830
(July 2005); doi:10.1038/nbt0705-828
| Full Text (HTML/PDF)

article
Enzymatic detection of protein translocation
Tom S Wehrman, Clayton L Casipit, Nevin M Gewertz and Helen M Blau
Nature Methods 2, 521–527
(July 2005); doi:10.1038/nmeth771
| Abstract | Full Text (HTML/PDF)

article
Blimp1 is a critical determinant of the germ cell lineage in mice
Yasuhide Ohinata , Bernhard Payer , Dónal O'Carroll , Katia Ancelin , Yukiko Ono , Mitsue Sano , Sheila C. Barton , Tetyana Obukhanych , Michel Nussenzweig , Alexander Tarakhovsky , Mitinori Saitou and M. Azim Surani
Nature 436, 207–213
(14 July 2005); doi:10.1038/nature03813
| Summary | Full Text (HTML / PDF) |

article
Serum response factor regulates a muscle-specific microRNA that targets Hand2 during cardiogenesis
Yong Zhao , Eva Samal and Deepak Srivastava
Nature 436, 214–220
(14 July 2005); doi:10.1038/nature03817
| Summary | Full Text (HTML / PDF) |

news and views
Developmental biology: Tiny brakes for a growing heart
Benoit G. Bruneau
Nature 436, 181–182
(14 July 2005); doi:10.1038/436181a
| Full Text (HTML / PDF) |

letter
Neurosphere-derived multipotent precursors promote neuroprotection by an immunomodulatory mechanism
Stefano Pluchino, Lucia Zanotti, Barbara Rossi, Elena Brambilla, Linda Ottoboni, Giuliana Salani, Marianna Martinello, Alessandro Cattalini, Alessandra Bergami, Roberto Furlan, Giancarlo Comi, Gabriela Constantin and Gianvito Martino
Nature 436, 266–271
(14 July 2005); doi:10.1038/nature03889
| First Paragraph | Full Text (HTML / PDF) |

letter
A substrate-specific inhibitor of protein translocation into the endoplasmic reticulum
Jennifer L. Garrison, Eric J. Kunkel, Ramanujan S. Hegde and Jack Taunton
Nature 436, 285–289
(14 July 2005); doi:10.1038/nature03821
| First Paragraph | Full Text (HTML / PDF) |

review article
Common mechanisms of nerve and blood vessel wiring
Peter Carmeliet and Marc Tessier-Lavigne
Nature 436, 193–200
(14 July 2005); doi:10.1038/nature03875
| Summary | Full Text (HTML / PDF) |

article
Endosome-to-cytosol transport of viral nucleocapsids
Isabelle Le Blanc, Pierre-Philippe Luyet, Véronique Pons, Charles Ferguson, Neil Emans, Anne Petiot, Nathalie Mayran, Nicolas Demaurex, Julien Fauré, Rémy Sadoul, Robert G. Parton and J. Gruenberg
Nature Cell Biology 7, 653–664
(July 2005); doi:10.1038/ncb1269
| Abstract | Full Text (HTML/PDF) |

news and views
Viral entry: a detour through multivesicular bodies
Pradeep Uchil and Walther Mothes
Nature Cell Biology 7, 641–642
(July 2005); doi:10.1038/ncb0705-641
| Full Text (HTML/PDF) |

letter
The Hedgehog-inducible ubiquitin ligase subunit WSB-1 modulates thyroid hormone activation and PTHrP secretion in the developing growth plate
Monica Dentice, Amitabha Bandyopadhyay, Balázs Gereben, Isabelle Callebaut, Marcelo A. Christoffolete, Brian W. Kim, Sahar Nissim, Jean-Paul Mornon, Ann Marie Zavacki, Anikó Zeöld, Luciane P. Capelo, Cyntia Curcio-Morelli, Rogério Ribeiro, John W. Harney, Clifford J. Tabin and Antonio C. Bianco
Nature Cell Biology 7, 698–705
(July 2005); doi:10.1038/ncb1272
| First Paragraph | Full Text (HTML/PDF) |

review article
Controlling nuclear receptors: the circular logic of cofactor cycles
Valentina Perissi and Michael G. Rosenfeld
Nature Reviews Molecular Cell Biology 6, 542–554
(July 2005); doi:10.1038/nrm1680
| Summary | Full Text (HTML / PDF) |

article
Suppressor of cytokine signaling 1 is required for the differentiation of CD4+ T cells
Ian M Catlett and Stephen M Hedrick
Nature Immunology 6, 715–721
(July 2005); doi:10.1038/ni1211
| Abstract | Full Text (HTML/PDF) |

news and views
A plague of autoantibodies
Vigo Heissmeyer, K Mark Ansel and Anjana Rao
Nature Immunology 6, 642–643
(July 2005); doi:10.1038/ni1214
| Full Text (HTML/PDF) |

review article
Tuning immune responses: diversity and adaptation of the immunological synapse
Peter Friedl, Annemieke Th. den Boer and Matthias Gunzer
Nature Reviews Immunology 5, 532–545
(July 2005); doi:10.1038/nri1647
| Summary | Full Text (HTML / PDF) |

article
Disabling poxvirus pathogenesis by inhibition of Abl-family tyrosine kinases
Patrick M Reeves, Bettina Bommarius, Sarah Lebeis, Shannon McNulty, Jens Christensen, Alyson Swimm, Ann Chahroudi, Rahul Chavan, Mark B Feinberg, Darren Veach, William Bornmann, Melanie Sherman and Daniel Kalman
Nature Medicine 11, 731–739
(July 2005); doi:10.1038/nm1265
| Abstract | Full Text (HTML/PDF) |

news and views
Gleevec casts a pox on poxviruses
Grant McFadden
Nature Medicine 11, 711–712
(July 2005); doi:10.1038/nm0705-711
| Full Text (HTML/PDF) |

review article
The role of focal-adhesion kinase in cancer — a new therapeutic opportunity
Gordon W. McLean, Neil O. Carragher, Egle Avizienyte, Jeff Evans, Valerie G. Brunton and Margaret C. Frame
Nature Reviews Cancer 5, 505–515
(July 2005); doi:10.1038/nrc1647
| Summary | Full Text (HTML / PDF) |

letter
TRPC6 is a glomerular slit diaphragm-associated channel required for normal renal function
Jochen Reiser, Krishna R Polu, Clemens C Möller, Peter Kenlan, Mehmet M Altintas, Changli Wei, Christian Faul, Stephanie Herbert, Ivan Villegas, Carmen Avila-Casado, Mary McGee, Hikaru Sugimoto, Dennis Brown, Raghu Kalluri, Peter Mundel, Paula L Smith, David E Clapham and Martin R Pollak
Nature Genetics 37, 739–744
(July 2005); doi:10.1038/ng1592
| First Paragraph | Full Text (HTML/PDF) |

news and views
A new TRP to kidney disease
Thomas Gudermann
Nature Genetics 37, 663–664
(July 2005); doi:10.1038/ng0705-663
| Full Text (HTML/PDF) |

article
GRIP1 controls dendrite morphogenesis by regulating EphB receptor trafficking
Casper C Hoogenraad, Aaron D Milstein, Iryna M Ethell, Mark Henkemeyer and Morgan Sheng
Nature Neuroscience 8, 906–915
(July 2005); doi:10.1038/nn1487
| Full Text (HTML/PDF) |

article
Dynamic mobility of functional GABAA receptors at inhibitory synapses
Philip Thomas, Martin Mortensen, Alastair M Hosie and Trevor G Smart
Nature Neuroscience 8, 889–897
(July 2005); doi:10.1038/nn1483
| Abstract | Full Text (HTML/PDF) |

news and views
EphB2 gets a GRIP on the dendritic arbor
Charu Misra and Edward B Ziff
Nature Neuroscience 8, 848–850
(July 2005); doi:10.1038/nn0705-848
| Full Text (HTML/PDF) |

brief communication
Dominant role of the GluR2 subunit in regulation of AMPA receptors by CaMKII
Michael C Oh and Victor A Derkach
Nature Neuroscience 8, 853–854
(July 2005); doi:10.1038/nn1476
| First Paragraph | Full Text (HTML/PDF) |

review article
Ageing and metabolism: drug discovery opportunities
Rory Curtis, Bard J. Geesaman and Peter S. DiStefano
Nature Reviews Drug Discovery AOP published online 24 June 2005; doi:10.1038/nrd1777
| Summary | Full Text (HTML / PDF) |

brief communications
Colony filtration blot: a new screening method for soluble protein expression in Escherichia coli
Tobias Cornvik, Sue-Li Dahlroth, Audur Magnusdottir, Maria Dolores Herman, Rosemarie Knaust, Monica Ekberg and Pär Nordlund
Nature Methods 2, 507–509
(July 2005); doi:10.1038/nmeth767
| Abstract | Full Text (HTML/PDF) |

article
Genome-wide analysis of human kinases in clathrin- and caveolae/raft-mediated endocytosis
Lucas Pelkmans, Eugenio Fava, Hannes Grabner, Michael Hannus, Bianca Habermann, Eberhard Krausz and Marino Zerial
Nature 436, 78–86
(07 July 2005); doi:10.1038/nature03571
| Summary | Full Text (HTML / PDF) |

letter
Nicotine reinforcement and cognition restored by targeted expression of nicotinic receptors
U. Maskos, B. E. Molles, S. Pons, M. Besson, B. P. Guiard, J.-P. Guilloux, A. Evrard, P. Cazala, A. Cormier, M. Mameli-Engvall, N. Dufour, I. Cloëz-Tayarani, A.-P. Bemelmans, J. Mallet, A. M. Gardier, V. David, P. Faure, S. Granon and J.-P. Changeux
Nature 436, 103–107
(07 July 2005); doi:10.1038/nature03694
| First Paragraph | Full Text (HTML / PDF) |

news and views
Neuroscience: A home for the nicotine habit
Julie A. Kauer
Nature 436, 31–32
(07 July 2005); doi:10.1038/436031a
| Full Text (HTML / PDF) |

letter
ATP is a mediator of chemosensory transduction in the central nervous system
Alexander V. Gourine, Enrique Llaudet, Nicholas Dale and K. Michael Spyer
Nature 436, 108–111
(07 July 2005); doi:10.1038/nature03690
| First Paragraph | Full Text (HTML / PDF) |

letter
Angiotensin-converting enzyme 2 protects from severe acute lung failure
Yumiko Imai, Keiji Kuba, Shuan Rao, Yi Huan, Feng Guo, Bin Guan, Peng Yang, Renu Sarao, Teiji Wada, Howard Leong-Poi, Michael A. Crackower, Akiyoshi Fukamizu, Chi-Chung Hui, Lutz Hein, Stefan Uhlig, Arthur S. Slutsky, Chengyu Jiang and Josef M. Penninger
Nature 436, 112–116
(07 July 2005); doi:10.1038/nature03712
| First Paragraph | Full Text (HTML / PDF) |

letter
Integrative genomic analyses identify MITF as a lineage survival oncogene amplified in malignant melanoma
Levi A. Garraway, Hans R. Widlund, Mark A. Rubin, Gad Getz, Aaron J. Berger, Sridhar Ramaswamy, Rameen Beroukhim, Danny A. Milner, Scott R. Granter, Jinyan Du, Charles Lee, Stephan N. Wagner, Cheng Li, Todd R. Golub , David L. Rimm, Matthew L. Meyerson , David E. Fisher and William R. Sellers
Nature 436, 117–122
(07 July 2005); doi:10.1038/nature03664
| First Paragraph | Full Text (HTML / PDF) |

news and views
Cancer biology: The weakest link?
Glenn Merlino
Nature 436, 33–35
(07 July 2005); doi:10.1038/436033a
| Full Text (HTML / PDF) |

letter
Rac1b and reactive oxygen species mediate MMP-3-induced EMT and genomic instability
Derek C. Radisky, Dinah D. Levy, Laurie E. Littlepage, Hong Liu, Celeste M. Nelson, Jimmie E. Fata, Devin Leake, Elizabeth L. Godden, Donna G. Albertson, M. Angela Nieto, Zena Werb and Mina J. Bissell
Nature 436, 123–127
(07 July 2005); doi:10.1038/nature03688
| First Paragraph | Full Text (HTML / PDF) |

letter
Kinase-regulated quantal assemblies and kiss-and-run recycling of caveolae
Lucas Pelkmans and Marino Zerial
Nature 436, 128–133
(07 July 2005); doi:10.1038/nature03866
| First Paragraph | Full Text (HTML / PDF) |

letter
Molecular basis of photoprotection and control of photosynthetic light-harvesting
Andrew A. Pascal, Zhenfeng Liu, Koen Broess, Bart van Oort, Herbert van Amerongen, Chao Wang, Peter Horton, Bruno Robert, Wenrui Chang and Alexander Ruban
Nature 436, 134–137
(07 July 2005); doi:10.1038/nature03795
| First Paragraph | Full Text (HTML / PDF) |

letter
X-ray structure of a tetranucleosome and its implications for the chromatin fibre
Thomas Schalch, Sylwia Duda, David F. Sargent and Timothy J. Richmond
Nature 436, 138–141
(07 July 2005); doi:10.1038/nature03686
| First Paragraph | Full Text (HTML / PDF) |

letter
Diego and Prickle regulate Frizzled planar cell polarity signalling by competing for Dishevelled binding
Andreas Jenny, Jessica Reynolds-Kenneally, Gishnu Das, Micheal Burnett and Marek Mlodzik
Nature Cell Biology 7, 691–697
(July 2005); doi:10.1038/ncb1271
| First Paragraph | Full Text (HTML/PDF) |

article
Role of Nbs1 in the activation of the Atm kinase revealed in humanized mouse models
Simone Difilippantonio, Arkady Celeste, Oscar Fernandez-Capetillo, Hua-Tang Chen, Bernardo Reina San Martin, Francois Van Laethem, Yong-Ping Yang, Galina V. Petukhova, Michael Eckhaus, Lionel Feigenbaum, Katia Manova, Michael Kruhlak, R. Daniel Camerini-Otero, Shyam Sharan, Michel Nussenzweig, and André Nussenzweig
Nature Cell Biology 7 675–685
(July 2005); doi:10.1038/ncb1270
| Abstract | Full Text (HTML/PDF) |

news and views
Nbs1 moving up in the world
Elena S. Stavridi and Thanos D. Halazonetis
Nature Cell Biology 7, 648–650
(July 2005); doi:10.1038/ncb0705-648
| Full Text (HTML/PDF) |

news and views
Huntingtin and the vicious circle
Jack Horne
Nature Cell Biology 7, 650
(July 2005); doi:10.1038/ncb0705-650
| Full Text (HTML/PDF) |

review article
AAA+ proteins: have engine, will work
Phyllis I. Hanson and Sidney W. Whiteheart
Nature Reviews Molecular Cell Biology 6, 519–529
(July 2005); doi:10.1038/nrm1684
| Summary | Full Text (HTML / PDF) |

article
CD70+ antigen-presenting cells control the proliferation and differentiation of T cells in the intestinal mucosa
Amale Laouar, Viraga Haridas, Dorothy Vargas, Xia Zhinan, David Chaplin, Rene A W van Lier and N Manjunath
Nature Immunology 6, 698–706
(July 2005); doi:10.1038/ni1212
| Abstract | Full Text (HTML/PDF) |

news and views
Affecting the effectors: a kick in the gut?
Cecilia Johansson and Brian L Kelsall
Nature Immunology 6, 644–646
(July 2005); doi:10.1038/ni0705-644
| Full Text (HTML/PDF) |

review article
New IL-12-family members: IL-23 and IL-27, cytokines with divergent functions
Christopher A. Hunter
Nature Reviews Immunology 5, 521–531
(July 2005); doi:10.1038/nri1648
| Summary | Full Text (HTML / PDF) |

article
Temporal dissection of p53 function in vitro and in vivo
Maria A Christophorou, Dionisio Martin-Zanca, Laura Soucek, Elizabeth R Lawlor, Lamorna Brown-Swigart, Emmy W Verschuren and Gerard I Evan
Nature Genetics 37, 718–726
(July 2005); doi:10.1038/ng1572
| Abstract | Full Text (HTML/PDF) |

article
DNER acts as a neuron-specific Notch ligand during Bergmann glial development
Mototsugu Eiraku, Akira Tohgo, Katsuhiko Ono, Megumi Kaneko, Kazuto Fujishima, Tomoo Hirano and Mineko Kengaku
Nature Neuroscience 8, 873–880
(July 2005); doi:10.1038/nn1492
| Abstract | Full Text (HTML/PDF) |

review article
Role of the Immune system in chronic pain
Fabien Marchand, Mauro Perretti and Stephen B. McMahon
Nature Reviews Neuroscience 6, 521–532
(July 2005); doi:10.1038/nrn1700
| Summary | Full Text (HTML / PDF) |

brief communications
Multiphoton excitation-evoked chromophore-assisted laser inactivation using green fluorescent protein
Takuji Tanabe, Masahito Oyamada, Katsumasa Fujita, Ping Dai, Hideo Tanaka and Tetsuro Takamatsu
Nature Methods 2, 503–505
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