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The Research Library categorizes, and provides access to, all recent signaling-related research published in the Nature Publishing Group journals. The selection is deliberately broad to facilitate access to all research impacting on the signaling community. Both primary research and review articles are included, as are 'News and Views' articles.
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article
Initial sequence of the chimpanzee genome and comparison with the human genome
The Chimpanzee Sequencing and Analysis Consortium
Nature 437, 69–87
(01 September 2005); doi:10.1038/nature04072
| Abstract | Full Text (HTML / PDF) |
article
A genome-wide comparison of recent chimpanzee and human segmental duplications
Ze Cheng, Mario Ventura, Xinwei She, Philipp Khaitovich, Tina Graves, Kazutoyo Osoegawa, Deanna Church, Pieter DeJong, Richard K. Wilson, Svante Pääbo, Mariano Rocchi and Evan E. Eichler
Nature 437, 88–93
(01 September 2005); doi:10.1038/nature04000
| Abstract | Full Text (HTML / PDF) |
letter
Sporadic immunogenic tumours avoid destruction by inducing T-cell tolerance
Gerald Willimsky and Thomas Blankenstein
Nature 437, 141–146
(01 September 2005); doi:10.1038/nature03954
| First Paragraph | Full Text (HTML / PDF) |
letter
Role of nucleophosmin in embryonic development and tumorigenesis
Silvia Grisendi, Rosa Bernardi, Marco Rossi, Ke Cheng, Luipa Khandker, Katia Manova and Pier Paolo Pandolfi
Nature 437, 147–153
(01 September 2005); doi:10.1038/nature03915
| First Paragraph | Full Text (HTML / PDF) |
letter
Prohibitin is required for Ras-induced Raf-MEK-ERK activation and epithelial cell migration
Krishnaraj Rajalingam, Christian Wunder, Volker Brinkmann, Yuri Churin, Mirko Hekman, Claudia Sievers, Ulf R. Rapp and Thomas Rudel
Nature Cell Biology 7, 837–843
(August 2005); doi:10.1038/ncb1283
| First Paragraph | Full Text (HTML/PDF) |
review article
Regulation of cadherin-mediated adhesion in morphogenesis
Barry M. Gumbiner
Nature Reviews Molecular Cell Biology 6, 622–634
(August 2005); doi:10.1038/nrm1699
| Abstract | Full Text (HTML / PDF) |
article
Pivotal function for cytoplasmic protein FROUNT in CCR2-mediated monocyte chemotaxis
Yuya Terashima, Nobuyuki Onai, Masako Murai, Masahiko Enomoto, Vongsakorn Poonpiriya, Tsuyoshi Hamada, Kazushi Motomura, Makiko Suwa, Taichi Ezaki, Tatsuya Haga, Shiro Kanegasaki and Kouji Matsushima
Nature Immunology 6, 827–835
(August 2005); doi:10.1038/ni1222
| Abstract | Full Text (HTML/PDF) |
review article
Dendritic-cell trafficking to lymph nodes through lymphatic vessels
Gwendalyn J. Randolph, Veronique Angeli and Melody A. Swartz
Nature Reviews Immunology 5, 617–628
(August 2005); doi:10.1038/nri1670
| Abstract | Full Text (HTML / PDF) |
article
Hyperactivation of Stat3 in gp130 mutant mice promotes gastric hyperproliferation and desensitizes TGF-β signaling
Brendan J Jenkins, Dianne Grail, Thao Nheu, Meri Najdovska, Bo Wang, Paul Waring, Melissa Inglese, Rachel M McLoughlin, Simon A Jones, Nicholas Topley, Heinz Baumann, Louise M Judd, Andrew S Giraud, Alex Boussioutas, Hong-Jian Zhu and Matthias Ernst
Nature Medicine 11, 845–852
(August 2005); doi:10.1038/nm1282
| Abstract | Full Text (HTML/PDF) |
article
Angiotensin II and EGF receptor cross-talk in chronic kidney diseases: a new therapeutic approach
Alexandre Lautrette, Shunqiang Li, Rohia Alili, Susan W Sunnarborg, Martine Burtin, David C Lee, Gérard Friedlander and Fabiola Terzi
Nature Medicine 11, 867–874
(August 2005); doi:10.1038/nm1275
| Abstract | Full Text (HTML/PDF) |
review article
Breast cancer metastasis: markers and models
Britta Weigelt, Johannes L. Peterse and Laura J. van't Veer
Nature Reviews Cancer 5, 591–602
(August 2005); doi:10.1038/nrc1670
| Abstract | Full Text (HTML / PDF) |
letter
Short double-stranded RNA induces transcriptional gene silencing in human cancer cells in the absence of DNA methylation
Angela H Ting, Kornel E Schuebel, James G Herman and Stephen B Baylin
Nature Genetics 37, 906–910
(August 2005); doi:10.1038/ng1611
| First Paragraph | Full Text (HTML/PDF) |
research article
In vivo imaging platform for tracking immunotherapeutic cells
Eric T Ahrens, Rafael Flores, Hongyan Xu and Penelope A Morel
Nature Biotechnology 23, 983–987
(August 2005); doi:10.1038/nbt1121
| First Paragraph | Full Text (HTML/PDF) |
news and views
Hot spot MRI emerges from the background
Jeff W M Bulte
Nature Biotechnology 23, 945–946
(August 2005); doi:10.1038/nbt0805-945
| Full Text (HTML/PDF) |
analysis
Probabilistic model of the human protein-protein interaction network
Daniel R Rhodes, Scott A Tomlins, Sooryanarayana Varambally, Vasudeva Mahavisno, Terrence Barrette, Shanker Kalyana-Sundaram, Debashis Ghosh, Akhilesh Pandey and Arul M Chinnaiyan
Nature Biotechnology 23, 951–959
(August 2005); doi:10.1038/nbt1103
| Abstract | Full Text (HTML/PDF) |
article
Real-time imaging of ligand-induced IKK activation in intact cells and in living mice
Shimon Gross and David Piwnica-Worms
Nature Methods 2, 607–614
(August 2005); doi:10.1038/nmeth779
| Abstract | Full Text (HTML/PDF) |
article
Myosin domain evolution and the primary divergence of eukaryotes
Thomas A. Richards and Thomas Cavalier-Smith
Nature 436, 1113–1118
(25 August 2005); doi:10.1038/nature03949
| Summary | Full Text (HTML / PDF) |
news and views
Evolution: A treasure trove of motors
Margaret A. Titus
Nature 436, 1097–1099
(25 August 2005); doi:10.1038/4361097a
| Full Text (HTML / PDF) |
article
Architecture of floral branch systems in maize and related grasses
Erik Vollbrecht, Patricia S. Springer, Lindee Goh, Edward S. Buckler IV and Robert Martienssen
Nature 436, 1119–1126
(25 August 2005); doi:10.1038/nature03892
| Summary | Full Text (HTML / PDF) |
letter
Translational control of hippocampal synaptic plasticity and memory by the eIF2α kinase GCN2
Mauro Costa-Mattioli, Delphine Gobert, Heather Harding, Barbara Herdy, Mounia Azzi, Martin Bruno, Michael Bidinosti, Cyrinne Ben Mamou, Edwige Marcinkiewicz, Madoka Yoshida, Hiroaki Imataka, A. Claudio Cuello, Nabil Seidah, Wayne Sossin, Jean-Claude Lacaille, David Ron, Karim Nader and Nahum Sonenberg
Nature 436, 1166–1173
(25 August 2005); doi:10.1038/nature03897
| First Paragraph | Full Text (HTML / PDF) |
letter
A new family of RhoGEFs activates the Rop molecular switch in plants
Antje Berken , Christoph Thomas and Alfred Wittinghofer
Nature 436, 1176–1180
(25 August 2005); doi:10.1038/nature03883
| First Paragraph | Full Text (HTML / PDF) |
letter
Hassall's corpuscles instruct dendritic cells to induce CD4+CD25+ regulatory T cells in human thymus
Norihiko Watanabe, Yi-Hong Wang, Heung Kyu Lee, Tomoki Ito, Yui-Hsi Wang, Wei Cao and Yong-Jun Liu
Nature 436, 1181–1185
(25 August 2005); doi:10.1038/nature03886
| First Paragraph | Full Text (HTML / PDF) |
letter
The DNA damage pathway regulates innate immune system ligands of the NKG2D receptor
Stephan Gasser, Sandra Orsulic, Eric J. Brown and David H. Raulet
Nature 436, 1186–1190
(25 August 2005); doi:10.1038/nature03884
| First Paragraph | Full Text (HTML / PDF) |
letter
Atomic model of a myosin filament in the relaxed state
John L. Woodhead, Fa-Qing Zhao, Roger Craig, Edward H. Egelman, Lorenzo Alamo and Raúl Padrón
Nature 436, 1195–1199
(25 August 2005); doi:10.1038/nature03920
| First Paragraph | Full Text (HTML / PDF) |
article
Membrane phosphatidylserine distribution as a non-apoptotic signalling mechanism in lymphocytes
James I. Elliott, Annmarie Surprenant, Federica M. Marelli-Berg, Joanne C. Cooper, Robin L. Cassady-Cain, Carol Wooding, Kenneth Linton, Denis R. Alexander and Christopher F. Higgins
Nature Cell Biology 7, 808–816
(August 2005); doi:10.1038/ncb1279
| Abstract | Full Text (HTML/PDF) |
letter
Temporal and spatial control of nucleophosmin by the Ran-Crm1 complex in centrosome duplication
Wei Wang, Anuradha Budhu, Marshonna Forgues and Xin Wei Wang
Nature Cell Biology 7, 823–830
(August 2005); doi:10.1038/ncb1282
| First Paragraph | Full Text (HTML/PDF) |
letter
Cdc2-cyclin E complexes regulate the G1/S phase transition
Eiman Aleem, Hiroaki Kiyokawa and Philipp Kaldis
Nature Cell Biology 7, 831–836
(August 2005); doi:10.1038/ncb1284
| First Paragraph | Full Text (HTML/PDF) |
news and views
Cdk1: the dominant sibling of Cdk2
Tarig Bashir and Michele Pagano
Nature Cell Biology 7, 779–781
(August 2005); doi:10.1038/ncb0805-779
| Full Text (HTML/PDF) |
review article
Transcriptional regulation and transformation by Myc proteins
Sovana Adhikary and Martin Eilers
Nature Reviews Molecular Cell Biology 6, 635–645
(August 2005); doi:10.1038/nrm1703
| Summary | Full Text (HTML / PDF) |
article
Stimulation of the vagus nerve attenuates macrophage activation by activating the Jak2-STAT3 signaling pathway
Wouter J de Jonge, Esmerij P van der Zanden, Frans O The, Maarten F Bijlsma, David J van Westerloo, Roelof J Bennink, Hans-Rudolf Berthoud, Satoshi Uematsu, Shizuo Akira, Rene M van den Wijngaard and Guy E Boeckxstaens
Nature Immunology 6, 844–851
(August 2005); doi:10.1038/ni1229
| Abstract | Full Text (HTML/PDF) |
news and views
It takes nerve to dampen inflammation
Christine N Metz and Kevin J Tracey
Nature Immunology 6, 756–757
(August 2005); doi:10.1038/ni0805-756
| Full Text (HTML/PDF) |
review article
Regulation of gene-activation pathways by PIAS proteins in the immune system
Ke Shuai and Bin Liu
Nature Reviews Immunology 5, 593–605
(August 2005); doi:10.1038/nri1667
| Summary | Full Text (HTML / PDF) |
article
Thiazolidinediones expand body fluid volume through PPARγ stimulation of ENaC-mediated renal salt absorption
YouFei Guan, Chuanming Hao, Dae Ryong Cha, Reena Rao, Wendell Lu, Donald E Kohan, Mark A Magnuson, Reyadh Redha, Yahua Zhang and Matthew D Breyer
Nature Medicine 11, 861–866
(August 2005); doi:10.1038/nm1278
| Abstract | Full Text (HTML/PDF) |
news and views
TZDs and diabetes: testing the waters
Clay F Semenkovich
Nature Medicine 11, 822–824
(August 2005); doi:10.1038/nm0805-822
| Full Text (HTML/PDF) |
review article
The TCL1 family of oncoproteins: co-activators of transformation
Michael A. Teitell
Nature Reviews Cancer 5, 640–648
(August 2005); doi:10.1038/nrc1672
| Summary | Full Text (HTML / PDF) |
letter
Plk4 haploinsufficiency causes mitotic infidelity and carcinogenesis
Michael A Ko, Carla O Rosario, John W Hudson, Sarang Kulkarni, Aaron Pollett, James W Dennis and Carol J Swallow
Nature Genetics 37 883–888
(2005); doi:10.1038/ng1605/
| First paragraph | Full Text (HTML/PDF) |
review article
Functions and mechanisms of retrograde neurotrophin signalling
Larry S. Zweifel, Rejji Kuruvilla and David D. Ginty
Nature Reviews Neuroscience 6, 615–625
(August 2005); doi:10.1038/nrn1727
| Summary | Full Text (HTML / PDF) |
research article
High-throughput generation of small antibacterial peptides with improved activity
Kai Hilpert, Rudolf Volkmer-Engert, Tess Walter and Robert E W Hancock
Nature Biotechnology 23, 1008–1012
(August 2005); doi:10.1038/nbt1113
| First Paragraph | Full Text (HTML/PDF) |
review article
Influenza: Lessons from past pandemics, warnings from current incidents
Taisuke Horimoto and Yoshihiro Kawaoka
Nature Reviews Microbiology 3, 591–600
(August 2005); doi:10.1038/nrmicro1208
| Summary | Full Text (HTML / PDF) |
article
Exotoxin A-eEF2 complex structure indicates ADP ribosylation by ribosome mimicry
René Jørgensen, A. Rod Merrill, Susan P. Yates, Victor E. Marquez, Adrian L. Schwan, Thomas Boesen and Gregers R. Andersen
Nature 436, 979–984
(18 August 2005); doi:10.1038/nature03871
| Abstract | Full Text (HTML / PDF) |
letter
Local translation of RhoA regulates growth cone collapse
Karen Y. Wu, Ulrich Hengst, Llewellyn J. Cox, Evan Z. Macosko, Andreas Jeromin, Erica R. Urquhart and Samie R. Jaffrey
Nature 436, 1020–1024
(18 August 2005); doi:10.1038/nature03885
| First Paragraph | Full Text (HTML / PDF) |
letter
Dystrophic heart failure blocked by membrane sealant poloxamer
Soichiro Yasuda, DeWayne Townsend, Daniel E. Michele, Elizabeth G. Favre, Sharlene M. Day and Joseph M. Metzger
Nature 436, 1025–1029
(18 August 2005); doi:10.1038/nature03844
| First Paragraph | Full Text (HTML / PDF) |
news and views
Cardiology: Rips repaired
Richard A. Steinhardt
Nature 436, 925
(18 August 2005); doi:10.1038/436925a
| Full Text (HTML / PDF) |
letter
ERM is required for transcriptional control of the spermatogonial stem cell niche
Chen Chen, Wenjun Ouyang, Vadim Grigura, Qing Zhou, Kay Carnes, Hyunjung Lim, Guang-Quan Zhao, Silvia Arber, Natasza Kurpios, Theresa L. Murphy, Alec M. Cheng, John A. Hassell, Varadaraj Chandrashekar, Marie-Claude Hofmann, Rex A. Hess and Kenneth M. Murphy
Nature 436, 1030–1034
(18 August 2005); doi:10.1038/nature03894
| First Paragraph | Full Text (HTML / PDF) |
letter
Deficiency of glutaredoxin 5 reveals Fe-S clusters are required for vertebrate haem synthesis
Rebecca A. Wingert, Jenna L. Galloway, Bruce Barut, Helen Foott, Paula Fraenkel, Jennifer L. Axe, Gerhard J. Weber, Kimberly Dooley, Alan J. Davidson, Bettina Schmidt, Barry H. Paw, George C. Shaw, Paul Kingsley, James Palis, Heidi Schubert, Opal Chen, Jerry Kaplan, The Tübingen 2000 Screen Consortium and Leonard I. Zon
Nature 436, 1035–1039
(18 August 2005); doi:10.1038/nature03887
| First Paragraph | Full Text (HTML / PDF) |
letter
Animal virus replication and RNAi-mediated antiviral silencing in Caenorhabditis elegans
R. Lu, M. Maduro, F. Li, H. W. Li, G. Broitman-Maduro, W. X. Li and S. W. Ding
Nature 436, 1040–1043
(18 August 2005); doi:10.1038/nature03870
| First Paragraph | Full Text (HTML / PDF) |
letter
RNA interference is an antiviral defence mechanism in Caenorhabditis elegans
Courtney Wilkins, Ryan Dishongh, Steve C. Moore, Michael A. Whitt, Marie Chow and Khaled Machaca
Nature 436, 1044–1047
(18 August 2005); doi:10.1038/nature03957
| First Paragraph | Full Text (HTML / PDF) |
letter
Conditional telomerase induction causes proliferation of hair follicle stem cells
Kavita Y. Sarin, Peggie Cheung, Daniel Gilison, Eunice Lee, Ruth I. Tennen, Estee Wang, Maja K. Artandi, Anthony E. Oro and Steven E. Artandi
Nature 436, 1048–1052
(18 August 2005); doi:10.1038/nature03836
| First Paragraph | Full Text (HTML / PDF) |
news and views
Cell biology: Shaggy mouse tales
Elizabeth H. Blackburn
Nature 436, 922–923
(18 August 2005); doi:10.1038/436922a
| Full Text (HTML / PDF) |
insight
Unravelling hepatitis C virus replication from genome to function
Brett D. Lindenbach and Charles M. Rice
Nature 436, 933–938
(18 August 2005); doi:10.1038/nature04077
| Abstract | Full Text (HTML / PDF) |
insight
Evasion of intracellular host defence by hepatitis C virus
Michael Gale Jr and Eileen M. Foy
Nature 436, 939–945
(18 August 2005); doi:10.1038/nature04078
| Abstract | Full Text (HTML / PDF) |
insight
Adaptive immune responses in acute and chronic hepatitis C virus infection
David G. Bowen and Christopher M. Walker
Nature 436, 946–952
(18 August 2005); doi:10.1038/nature04079
| Abstract | Full Text (HTML / PDF) |
insight
Mechanism of action of interferon and ribavirin in treatment of hepatitis C
Jordan J. Feld and Jay H. Hoofnagle
Nature 436, 967–972
(18 August 2005); doi:10.1038/nature04082
| Abstract | Full Text (HTML / PDF) |
letter
Functional role of the AAA peroxins in dislocation of the cycling PTS1 receptor back to the cytosol
Harald W. Platta, Silke Grunau, Katja Rosenkranz, Wolfgang Girzalsky and Ralf Erdmann
Nature Cell Biology 7, 817–822
(August 2005); doi:10.1038/ncb1281
| First Paragraph | Full Text (HTML/PDF) |
review article
Interleukin-1 and neuronal injury
Stuart M. Allan, Pippa J. Tyrrell and Nancy J. Rothwell
Nature Reviews Immunology 5, 629–640
(August 2005); doi:10.1038/nri1664
| Abstract | Full Text (HTML / PDF) |
letter
Intracellular protein therapy with SOCS3 inhibits inflammation and apoptosis
Daewoong Jo, Danya Liu, Shan Yao, Robert D Collins and Jacek Hawiger
Nature Medicine 11, 892–898
(August 2005); doi:10.1038/nm1269
| First Paragraph | Full Text (HTML/PDF) |
review article
Using Drosophila melanogaster to map human cancer pathways
Anthony M. Brumby and Helena E. Richardson
Nature Reviews Cancer 5, 626–639
(August 2005); doi:10.1038/nrc1671
| Abstract | Full Text (HTML / PDF) |
article
Nova regulates brain-specific splicing to shape the synapse
Jernej Ule, Alja Ule, Joanna Spencer, Alan Williams, Jing-Shan Hu, Melissa Cline, Hui Wang, Tyson Clark, Claire Fraser, Matteo Ruggiu, Barry R Zeeberg, David Kane, John N Weinstein, John Blume and Robert B Darnell
Nature Genetics 37, 844–852
(August 2005); doi:10.1038/ng1610
| Abstract | Full Text (HTML/PDF) |
news and views
Splicing on the brain
Benjamin J Blencowe
Nature Genetics 37, 796–797
(August 2005); doi:10.1038/ng0805-796
| Full Text (HTML/PDF) |
article
Activation of p75NTR by proBDNF facilitates hippocampal long-term depression
Newton H Woo, Henry K Teng, Chia-Jen Siao, Cristina Chiaruttini, Petti T Pang, Teresa A Milner, Barbara L Hempstead and Bai Lu
Nature Neuroscience 8, 1069–1077
(August 2005); doi:10.1038/nn1510
| Abstract | Full Text (HTML/PDF) |
research article
Integrative model of the response of yeast to osmotic shock
Edda Klipp, Bodil Nordlander, Roland Krüger, Peter Gennemark and Stefan Hohmann
Nature Biotechnology 23, 975–982
(August 2005); doi:10.1038/nbt1114
| Abstract | Full Text (HTML/PDF) |
news and views
Closing the circle of osmoregulation
Patrik D'haeseleer
Nature Biotechnology 23, 941–942
(August 2005); doi:10.1038/nbt0805-941
| Full Text (HTML/PDF) |
scientific report
Anopheles gambiae SRPN2 facilitates midgut invasion by the malaria parasite Plasmodium berghei
Kristin Michel, Aidan Budd, Sofia Pinto, Toby J Gibson and Fotis C Kafatos
EMBO Reports AOP
(12 August 2005); doi:10.1038/sj.embor.7400478
| Full Text (HTML / PDF) |
article
Evasion of the p53 tumour surveillance network by tumour-derived MYC mutants
Michael T. Hemann, Anka Bric, Julie Teruya-Feldstein, Andreas Herbst, Jonas A. Nilsson, Carlos Cordon-Cardo, John L. Cleveland, William P. Tansey and Scott W. Lowe
Nature 436, 807–811
(11 August 2005); doi:10.1038/nature03845
| Abstract | Full Text (HTML / PDF) |
news and views
Cancer: Two in one
Anton Berns
Nature 436, 787–789
(11 August 2005); doi:10.1038/436787a
| Full Text (HTML / PDF) |
article
A contractile nuclear actin network drives chromosome congression in oocytes
Péter Lénárt, Christian P. Bacher, Nathalie Daigle, Arthur R. Hand, Roland Eils, Mark Terasaki and Jan Ellenberg
Nature 436, 812–818
(11 August 2005); doi:10.1038/nature03810
| Abstract | Full Text (HTML / PDF) |
letter
The hangover gene defines a stress pathway required for ethanol tolerance development
Henrike Scholz, Mirjam Franz and Ulrike Heberlein
Nature 436, 845–847
(11 August 2005); doi:10.1038/nature03864
| First Paragraph | Full Text (HTML / PDF) |
letter
The ERECTA gene regulates plant transpiration efficiency in Arabidopsis
Josette Masle, Scott R. Gilmore and Graham D. Farquhar
Nature 436, 866–870
(11 August 2005); doi:10.1038/nature03835
| First Paragraph | Full Text (HTML / PDF) |
letter
Identification of JAK/STAT signalling components by genome-wide RNA interference
Patrick Müller, David Kuttenkeuler, Viola Gesellchen, Martin P. Zeidler and Michael Boutros
Nature 436, 871–875
(11 August 2005); doi:10.1038/nature03869
| First Paragraph | Full Text (HTML / PDF) |
letter
Voltage-sensor activation with a tarantula toxin as cargo
L. Revell Phillips, Mirela Milescu, Yingying Li-Smerin, Joseph A. Mindell, Jae Il Kim and Kenton J. Swartz
Nature 436, 857–860
(11 August 2005); doi:10.1038/nature03873
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letter
Gating charge displacement in voltage-gated ion channels involves limited transmembrane movement
Baron Chanda, Osei Kwame Asamoah, Rikard Blunck, Benoît Roux and Francisco Bezanilla
Nature 436, 852–856
(11 August 2005); doi:10.1038/nature03888
| First Paragraph | Full Text (HTML / PDF) |
letter
Small vertical movement of a K+ channel voltage sensor measured with luminescence energy transfer
David J. Posson, Pinghua Ge, Christopher Miller, Francisco Bezanilla and Paul R. Selvin
Nature 436, 848–851
(11 August 2005); doi:10.1038/nature03819
| First Paragraph | Full Text (HTML / PDF) |
letter
A high-resolution map of active promoters in the human genome
Tae Hoon Kim, Leah O. Barrera, Ming Zheng, Chunxu Qu, Michael A. Singer, Todd A. Richmond, Yingnian Wu, Roland D. Green and Bing Ren
Nature 436, 876–880
(11 August 2005); doi:10.1038/nature03877
| First Paragraph | Full Text (HTML / PDF) |
brief communication
Colorectal cancer: Mutations in a signalling pathway
D. Williams Parsons, Tian-Li Wang, Yardena Samuels, Alberto Bardelli, Jordan M. Cummins, Laura DeLong, Natalie Silliman, Janine Ptak, Steve Szabo, James K. V. Willson, Sanford Markowitz, Kenneth W. Kinzler, Bert Vogelstein, Christoph Lengauer and Victor E. Velculescu
Nature 436, 792
(11 August 2005); doi:10.1038/436792a
| First Paragraph | Full Text (HTML / PDF) |
article
A novel and evolutionarily conserved PtdIns(3,4,5)P3-binding domain is necessary for DOCK180 signalling
Jean-François Côté, Andrea B. Motoyama, Jason A. Bush and Kristiina Vuori
Nature Cell Biology 7, 797–807
(August 2005); doi:10.1038/ncb1280
| Abstract | Full Text (HTML/PDF) |
review article
Basement membrane proteoglycans: from cellar to ceiling
Renato V. Iozzo
Nature Reviews Molecular Cell Biology 6, 646–656
(August 2005); doi:10.1038/nrm1702
| Abstract | Full Text (HTML / PDF) |
article
Nonstimulatory peptides contribute to antigen-induced CD8-T cell receptor interaction at the immunological synapse
Pia P Yachi, Jeanette Ampudia, Nicholas R J Gascoigne and Tomasz Zal
Nature Immunology 6, 785–792
(August 2005); doi:10.1038/ni1220
| Abstract | Full Text (HTML/PDF) |
review article
Regulation of immune responses by L-arginine metabolism
Vincenzo Bronte and Paola Zanovello
Nature Reviews Immunology 5, 641–654
(August 2005); doi:10.1038/nri1668
| Abstract | Full Text (HTML / PDF) |
letter
A crucial role of angiotensin converting enzyme 2 (ACE2) in SARS coronavirus-induced lung injury
Keiji Kuba, Yumiko Imai, Shuan Rao, Hong Gao, Feng Guo, Bin Guan, Yi Huan, Peng Yang, Yanli Zhang, Wei Deng, Linlin Bao, Binlin Zhang, Guang Liu, Zhong Wang, Mark Chappell, Yanxin Liu, Dexian Zheng, Andreas Leibbrandt, Teiji Wada, Arthur S Slutsky, Depei Liu, Chuan Qin, Chengyu Jiang and Josef M Penninger
Nature Medicine 11, 875–879
(August 2005); doi:10.1038/nm1267
| First Paragraph | Full Text (HTML/PDF) |
news and views
Good ACE, bad ACE do battle in lung injury, SARS
John Nicholls and Malik Peiris
Nature Medicine 11, 821–822
(August 2005); doi:10.1038/nm0805-821
| Full Text (HTML/PDF) |
article
Mutations in TNFRSF13B encoding TACI are associated with common variable immunodeficiency in humans
U Salzer, H M Chapel, A D B Webster, Q Pan-Hammarström, A Schmitt-Graeff, M Schlesier, H H Peter, J K Rockstroh, P Schneider, A A Schäffer, L Hammarström and B Grimbacher
Nature Genetics 37, 820–828
(August 2005); doi:10.1038/ng1600
| Abstract | Full Text (HTML/PDF) |
article
TACI is mutant in common variable immunodeficiency and IgA deficiency
Emanuela Castigli, Stephen A Wilson, Lilit Garibyan, Rima Rachid, Francisco Bonilla, Lynda Schneider and Raif S Geha
Nature Genetics 37, 829–834
(August 2005); doi:10.1038/ng1601
| Abstract | Full Text (HTML/PDF) |
news and views
Unraveling TACIt functions
Flavius Martin and Vishva M Dixit
Nature Genetics 37, 793–794
(August 2005); doi:10.1038/ng0805-793
| Full Text (HTML/PDF) |
review article
Telomeres and human disease: ageing, cancer and beyond
Maria A. Blasco
Nature Reviews Genetics 6, 611–622
(August 2005); doi:10.1038/nrg1656
| Abstract | Full Text (HTML / PDF) |
article
Regulation of NMDA receptor trafficking by amyloid-β
Eric M Snyder, Yi Nong, Claudia G Almeida, Surojit Paul, Timothy Moran, Eun Young Choi, Angus C Nairn, Michael W Salter, Paul J Lombroso, Gunnar K Gouras and Paul Greengard
Nature Neuroscience 8, 1051–1058
(August 2005); doi:10.1038/nn1503
| Abstract | Full Text (HTML/PDF) |
news and views
The synaptic Aβ hypothesis of Alzheimer disease
Rudolph E Tanzi
Nature Neuroscience 8, 977–979
(August 2005); doi:10.1038/nn0805-977
| Full Text (HTML/PDF) |
review article
The yin and yang of neurotrophin action
Bai Lu, Petti T. Pang and Newton H. Woo
Nature Reviews Neuroscience 6, 603–614
(August 2005); doi:10.1038/nrn1726
| Abstract | Full Text (HTML / PDF) |
review article
Leukotriene modifiers as potential therapeutics for cardiovascular disease
Colin D. Funk
Nature Reviews Drug Discovery 4, 664–672
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Oncogene-induced senescence as an initial barrier in lymphoma development
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Nature 436, 660–665
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Licensing of natural killer cells by host major histocompatibility complex class I molecules
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Nature 436, 709–713
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Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis
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Nature 436, 725–730
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BRAFE600-associated senescence-like cell cycle arrest of human naevi
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Nature 436, 720–724
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A cytokinesis furrow is positioned by two consecutive signals
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Nature 436, 731–734
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Transcription of mammalian messenger RNAs by a nuclear RNA polymerase of mitochondrial origin
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TRBP recruits the Dicer complex to Ago2 for microRNA processing and gene silencing
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brief communications
Tumour biology: Senescence in premalignant tumours
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Nature 436, 642
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news and views
Cancer: Crime and punishment
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Nature 436, 636–637
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Protein kinase activity of phosphoinositide 3-kinase regulates β-adrenergic receptor endocytosis
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Nature Cell Biology 7, 785–796
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Substrate specificity: PI(3)Kγ has it both ways
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Nature Cell Biology 7, 773–774
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Ubiquitin and ubiquitin-like proteins as multifunctional signals
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Nature Reviews Molecular Cell Biology 6, 599–609
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Selected Toll-like receptor agonist combinations synergistically trigger a T helper type 1-polarizing program in dendritic cells
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Nature Immunology 6, 769–776
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'TaiLoRing' the response of dendritic cells to pathogens
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Nature Immunology 6, 749–750
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Toll-like receptor-mediated cytokine production is differentially regulated by glycogen synthase kinase 3
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Nature Immunology 6, 777–784
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GSK3: an in-Toll-erant protein kinase?
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Nature Immunology 6, 751–752
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Rac GTPases differentially integrate signals regulating hematopoietic stem cell localization
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Nature Medicine 11, 886–891
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Id family of helix-loop-helix proteins in cancer
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Nature Reviews Cancer 5, 603–614
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Chromosome-wide and promoter-specific analyses identify sites of differential DNA methylation in normal and transformed human cells
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Nature Genetics 37, 853–862
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Distinct triggering and expression mechanisms underlie LTD of AMPA and NMDA synaptic responses
Wade Morishita, Helene Marie and Robert C Malenka
Nature Neuroscience 8, 1043–1050
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A bacterial one-hybrid system for determining the DNA-binding specificity of transcription factors
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Nature Biotechnology 23, 988–994
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Discovering DNA regulatory elements with bacteria
Martha L Bulyk
Nature Biotechnology 23, 942–944
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The vagus nerve and the nicotinic anti-inflammatory pathway
Luis Ulloa
Nature Reviews Drug Discovery 4, 673–684
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