The Research Library categorizes, and provides access to, all recent signaling-related research published in the Nature Publishing Group journals. The selection is deliberately broad to facilitate access to all research impacting on the signaling community. Both primary research and review articles are included, as are 'News and Views' articles.
Click here for free access to the 'Featured Articles' section, with new articles every week.
letter NMDA receptors are expressed in oligodendrocytes and activated in ischaemia
Ragnhildur Káradóttir, Pauline Cavelier, Linda H. Bergersen and David Attwell Nature438, 1162–1166
(22 December 2005); doi:10.1038/nature04302
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letter NMDA receptors are expressed in developing oligodendrocyte processes and mediate injury
Michael G. Salter and Robert Fern Nature438, 1167–1171
(22 December 2005); doi:10.1038/nature04301
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letter WUSCHEL controls meristem function by direct regulation of cytokinin-inducible response regulators
Andrea Leibfried, Jennifer P. C. To, Wolfgang Busch, Sandra Stehling, Andreas Kehle, Monika Demar, Joseph J. Kieber and Jan U. Lohmann Nature438, 1172–1175
(22 December 2005); doi:10.1038/nature04270
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letter Histone H3 serine 10 phosphorylation by Aurora B causes HP1 dissociation from heterochromatin
Toru Hirota, Jesse J. Lipp, Ban-Hock Toh and Jan-Michael Peters Nature438, 1176–1180
(22 December 2005); doi:10.1038/nature04254
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letter Double chromodomains cooperate to recognize the methylated histone H3 tail
John F. Flanagan, Li-Zhi Mi, Maksymilian Chruszcz, Marcin Cymborowski, Katrina L. Clines, Youngchang Kim, Wladek Minor, Fraydoon Rastinejad and Sepideh Khorasanizadeh Nature438, 1181–1185
(22 December 2005); doi:10.1038/nature04290
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article Polycystin-1 and polycystin-2 regulate the cell cycle through the helix-loop-helix inhibitor Id2
Xiaogang Li, Ying Luo, Patrick G. Starremans, Coleen A. McNamara, York Pei and Jing Zhou Nature Cell Biology7, 1202–1212
(December 2005); doi:10.1038/ncb1326
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news and views Cadherins reach out
Alison Schuldt Nature Cell Biology7, 1166
(December 2005); doi:10.1038/ncb1205-1066
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letter Prevention of early flowering by expression of FLOWERING LOCUS C requires methylation of histone H3 K36
Zhong Zhao, Yu Yu, Denise Meyer, Chengjun Wu and Wen-Hui Shen Nature Cell Biology7, 1256–1260
(December 2005); doi:10.1038/ncb1329
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news and views Apoptosis: eating sensibly
Christopher D. Gregory and Simon B. Brown Nature Cell Biology7, 1161–1163
(December 2005); doi:10.1038/ncb1205-1061
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article Sphingosine 1-phosphate type 1 receptor agonism inhibits transendothelial migration of medullary T cells to lymphatic sinuses
Sindy H Wei, Hugh Rosen, Melanie P Matheu, M Germana Sanna, Sheng-Kai Wang, Euijung Jo, Chi-Huey Wong, Ian Parker and Michael D Cahalan Nature Immunology6, 1228–1235
(December 2005); doi:10.1038/ni1269
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Review article Immunity by ubiquitylation: a reversible process of modification
Yun-Cai Liu, Josef Penninger and Michael Karin Nature Reviews Immunology5, 941–952
(December 2005); doi:10.1038/nri1731
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article Trans-arachidonic acids generated during nitrative stress induce a thrombospondin-1-dependent microvascular degeneration
Elsa Kermorvant-Duchemin, Florian Sennlaub, Mirna Sirinyan, Sonia Brault, Gregor Andelfinger, Amna Kooli, Stéphane Germain, Huy Ong, Pedro d'Orleans-Juste, Fernand Gobeil, Jr Tang Zhu, Chantal Boisvert, Pierre Hardy, Kavita Jain, J Russel Falck, Michael Balazy and Sylvain Chemtob Nature Medicine11, 1339–1345
(December 2005); doi:10.1038/nm1336
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news and views A radically twisted lipid regulates vascular death
Lois E H Smith and Kip M Connor Nature Medicine11, 1275–1276
(December 2005); doi:10.1038/nm1205-1275
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Review article Oncogenic PI3K deregulates transcription and translation
Andreas G. Bader, Sohye Kang, Li Zhao and Peter K. Vogt Nature Reviews Cancer5, 921–929
(December 2005); doi:10.1038/nrc1753
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letter Deficiency of UBR1, a ubiquitin ligase of the N-end rule pathway, causes pancreatic dysfunction, malformations and mental retardation (Johanson-Blizzard syndrome)
Martin Zenker, Julia Mayerle, Markus M Lerch, Andreas Tagariello, Klaus Zerres, Peter R Durie, Matthias Beier, Georg Hülskamp, Celina Guzman, Helga Rehder, Frits A Beemer, Ben Hamel, Philippe Vanlieferinghen, Ruth Gershoni-Baruch, Marta W Vieira, Miroslav Dumic, Ron Auslender, Vera L Gil-da-Silva-Lopes, Simone Steinlicht, Manfred Rauh, Stavit A Shalev, Christian Thiel, Andreas Winterpacht, Yong Tae Kwon, Alexander Varshavsky and André Reis Nature Genetics37, 1345–1350
(December 2005); doi:10.1038/ng1681
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article FARP2 triggers signals for Sema3A-mediated axonal repulsion
Toshihiko Toyofuku, Junko Yoshida, Tamiko Sugimoto, Hong Zhang, Atsushi Kumanogoh, Masatsugu Hori and Hitoshi Kikutani Nature Neuroscience8, 1712–1719
(December 2005); doi:10.1038/nn1596
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news and views Tinker to Evers to Chance: semaphorin signaling takes teamwork
Paul A Garrity Nature Neuroscience8, 1635–1636
(December 2005); doi:10.1038/nn1205-1635
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review article Anti-Inflammatory Effects of Statins: Clinical Evidence and Basic Mechanisms
Mukesh K. Jain and Paul M. Ridker Nature Reviews Drug Discovery4, 977–987
(December 2005); doi:10.1038/nrd1901
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article A look back: getting the message
Michael Eisenstein Nature Methods2, 996
(December 2005); doi:10.1038/nmeth1205-996
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research article Artificial cell-cell communication in yeast Saccharomyces cerevisiae using signaling elements from Arabidopsis thaliana
Ming-Tang Chen and Ron Weiss Nature Biotechnology23, 1551–1555
(December 2005); doi:10.1038/nbt1162
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article A promiscuous liaison between IL-15 receptor and Axl receptor tyrosine kinase in cell death control
Vadim Budagian, Elena Bulanova, Zane Orinska, Lutz Thon, Uwe Mamat1, Paola Bellosta, Claudio Basilico, Dieter Adam, Ralf Paus and Silvia Bulfone-Paus The EMBO Journal24, 4260–4270
(December 2005); doi:10.1038/sj.emboj.7600874
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article Regulation of G0 entry by the Pho80—Pho85 cyclin—CDK complex
Valeria Wanke, Ivo Pedruzzi, Elisabetta Cameroni, Frédérique Dubouloz and Claudio De Virgilio The EMBO Journal24, 4271–4278
(December 2005); doi:10.1038/sj.emboj.7600889
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article Probing ion-channel pores one proton at a time
Gisela D. Cymes, Ying Ni and Claudio Grosman Nature438, 975–980
(15 December 2005); doi:10.1038/nature04293
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article Hypomethylation-linked activation of PAX2 mediates tamoxifen-stimulated endometrial carcinogenesis
Huijian Wu, Yupeng Chen, Jing Liang, Bin Shi, Ge Wu, Ying Zhang, Dan Wang, Ruifang Li, Xia Yi, Hua Zhang, Luyang Sun and Yongfeng Shang Nature438, 981–987
(15 December 2005); doi:10.1038/nature04225
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letter A RhoGDP dissociation inhibitor spatially regulates growth in root hair cells
Rachel J. Carol, Seiji Takeda, Paul Linstead, Marcus C. Durrant, Hana Kakesova, Paul Derbyshire, Sinéad Drea, Viktor Zarsky and Liam Dolan Nature438, 1013–1016
(15 December 2005); doi:10.1038/nature04198
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letter BDNF from microglia causes the shift in neuronal anion gradient underlying neuropathic pain
Jeffrey A. M. Coull , Simon Beggs, Dominic Boudreau, Dominick Boivin, Makoto Tsuda, Kazuhide Inoue, Claude Gravel, Michael W. Salter and Yves De Koninck Nature438, 1017–1021
(15 December 2005); doi:10.1038/nature04223
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letter The Rae1-Nup98 complex prevents aneuploidy by inhibiting securin degradation
Karthik B. Jeganathan, Liviu Malureanu and Jan M. van Deursen Nature438, 1036–1039
(15 December 2005); doi:10.1038/nature04221
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news and views Developmental biology: A message to the back side
Wolfgang Driever Nature438, 926–927
(15 December 2005); doi:10.1038/438926b
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article Regulation of Notch signalling by non-visual β-arrestin
Ashim Mukherjee, Alexey Veraksa, Andreas Bauer, Carine Rosse, Jacques Camonis and Spyros Artavanis-Tsakonas Nature Cell Biology7, 1191–1201
(December 2005); doi:10.1038/ncb1327
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news and views Receptor regulation: β-arrestin moves up a notch
Sudha K. Shenoy & Robert J. Lefkowitz Nature Cell Biology7, 1159–1161
(December 2005); doi:10.1038/ncb1205-1059
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letter Differential role of CENP-A in the segregation of holocentric C. elegans chromosomes during meiosis and mitosis
Joost Monen, Paul S. Maddox, Francie Hyndman, Karen Oegema and Arshad Desai Nature Cell Biology7, 1248–1255
(December 2005); doi:10.1038/ncb1331
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review article Arp2/3 and SCAR: plants move to the fore
Michael J. Deeks and Patrick J. Hussey Nature Reviews Molecular Cell Biology6, 954–964
(December 2005); doi:10.1038/nrm1765
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article The peptidyl-prolyl isomerase Pin1 regulates the stability of granulocyte-macrophage colony-stimulating factor mRNA in activated eosinophils
Zhong-Jian Shen, Stephane Esnault and James S Malter Nature Immunology6, 1280–1287
(December 2005); doi:10.1038/ni1266
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news and views Pin1: a proline isomerase that makes you wheeze?
Paul Anderson Nature Immunology6, 1211–1212
(December 2005); doi:10.1038/ni1205-1211
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article IKK mediates ischemia-induced neuronal death
Oliver Herrmann, Bernd Baumann, Rossana de Lorenzi, Sajjad Muhammad, Wen Zhang, Jens Kleesiek, Max Malfertheiner, Martin Köhrmann, Ioana Potrovita, Ira Maegele, Cordian Beyer, James R Burke, Mazahir T Hasan, Hermann Bujard, Thomas Wirth, Manolis Pasparakis and Markus Schwaninger Nature Medicine11, 1322–1329
(December 2005); doi:10.1038/nm1323
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letter R-Ras is a global regulator of vascular regeneration that suppresses intimal hyperplasia and tumor angiogenesis
Masanobu Komatsu and Erkki Ruoslahti Nature Medicine11, 1346–1350
(December 2005); doi:10.1038/nm1324
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review article A role for Kaiso-p120ctn complexes in cancer?
Frans M. van Roy and Pierre D. McCrea Nature Reviews Cancer5, 956–964
(December 2005); doi:10.1038/nrc1752
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brief communication The gene disrupted in Marinesco-Sjögren syndrome encodes SIL1, an HSPA5 cochaperone
Anna-Kaisa Anttonen, Ibrahim Mahjneh, Riikka H Hämäläinen, Clotilde Lagier-Tourenne, Outi Kopra, Laura Waris, Mikko Anttonen, Tarja Joensuu, Hannu Kalimo, Anders Paetau, Lisbeth Tranebjaerg, Denys Chaigne, Michel Koenig, Orvar Eeg-Olofsson, Bjarne Udd, Mirja Somer, Hannu Somer and Anna-Elina Lehesjoki Nature Genetics37, 1309–1311
(December 2005); doi:10.1038/ng1677
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brief communication Mutations in SIL1 cause Marinesco-Sjögren syndrome, a cerebellar ataxia with cataract and myopathy
Jan Senderek, Michael Krieger, Claudia Stendel, Carsten Bergmann, Markus Moser, Nico Breitbach-Faller, Sabine Rudnik-Schöneborn, Astrid Blaschek, Nicole I Wolf, Inga Harting, Kathryn North, Janine Smith, Francesco Muntoni, Martin Brockington, Susana Quijano-Roy, Francis Renault, Ralf Herrmann, Linda M Hendershot, J Michael Schröder, Hanns Lochmüller, Haluk Topaloglu, Thomas Voit, Joachim Weis, Friedrich Ebinger and Klaus Zerres Nature Genetics37, 1312–1314
(December 2005); doi:10.1038/ng1678
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news and views SILencing misbehaving proteins
Huda Y Zoghbi Nature Genetics37, 1302–1303
(December 2005); doi:10.1038/ng1205-1302
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protocol Stable expression of fluorescently tagged proteins for studies of mitosis in mammalian cells
Patricia Wadsworth, Nasser M Rusan, U Serdar Tulu and Carey Fagerstrom Nature Methods2, 981–987
(December 2005); doi:10.1038/nmeth1205-981
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article Genome sequence, comparative analysis and haplotype structure of the domestic dog
Kerstin Lindblad-Toh, Claire M Wade, Tarjei S. Mikkelsen, Elinor K. Karlsson, David B. Jaffe, Michael Kamal, Michele Clamp, Jean L. Chang, Edward J. Kulbokas, III, Michael C. Zody, Evan Mauceli, Xiaohui Xie, Matthew Breen, Robert K. Wayne, Elaine A. Ostrander, Chris P. Ponting, Francis Galibert, Douglas R. Smith, Pieter J. deJong, Ewen Kirkness, Pablo Alvarez, Tara Biagi, William Brockman, Jonathan Butler, Chee-Wye Chin, April Cook, James Cuff, Mark J. Daly, David DeCaprio, Sante Gnerre, Manfred Grabherr, Manolis Kellis, Michael Kleber, Carolyne Bardeleben, Leo Goodstadt, Andreas Heger, Christophe Hitte, Lisa Kim, Klaus-Peter Koepfli, Heidi G. Parker, John P. Pollinger, Stephen M. J. Searle, Nathan B. Sutter, Rachael Thomas and Caleb Webber, Broad Sequencing Platform members and Eric S. Lander Nature438, 803–819
(08 December 2005); doi:10.1038/nature04338
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news and views Genomics: The dog has its day
Hans Ellegren Nature438, 745–746
(08 December 2005); doi:10.1038/438745a
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article VEGFR1-positive haematopoietic bone marrow progenitors initiate the pre-metastatic niche
Rosandra N. Kaplan , Rebecca D. Riba , Stergios Zacharoulis , Anna H. Bramley, Loïc Vincent, Carla Costa, Daniel D. MacDonald, David K. Jin, Koji Shido, Scott A. Kerns, Zhenping Zhu, Daniel Hicklin, Yan Wu, Jeffrey L. Port, Nasser Altorki, Elisa R. Port, Davide Ruggero, Sergey V. Shmelkov, Kristian K. Jensen, Shahin Rafii and David Lyden Nature438, 820–827
(08 December 2005); doi:10.1038/nature04186
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news and views Cancer biology: Emissaries set up new sites
Patricia S. Steeg Nature438, 750–751
(08 December 2005); doi:10.1038/438750b
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letter BMP inhibition-driven regulation of six-3 underlies induction of newt lens regeneration
Matthew W. Grogg, Mindy K. Call, Mitsumasa Okamoto, M. Natalia Vergara, Katia Del Rio-Tsonis and Panagiotis A. Tsonis Nature438, 858–862
(08 December 2005); doi:10.1038/nature04175
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letter Casein kinase 1 γ couples Wnt receptor activation to cytoplasmic signal transduction
Gary Davidson, Wei Wu, Jinlong Shen, Josipa Bilic, Ursula Fenger, Peter Stannek, Andrei Glinka and Christof Niehrs Nature438, 867–872
(08 December 2005); doi:10.1038/nature04170
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letter A dual-kinase mechanism for Wnt co-receptor phosphorylation and activation
Xin Zeng, Keiko Tamai, Brad Doble, Shitao Li, He Huang, Raymond Habas, Heidi Okamura, Jim Woodgett and Xi He Nature438, 873–877
(08 December 2005); doi:10.1038/nature04185
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news and views Cell biology: Relays at the membrane
Roel Nusse Nature438, 747–749
(08 December 2005); doi:10.1038/438747a
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letter The importance of sequence diversity in the aggregation and evolution of proteins
Caroline F. Wright, Sarah A. Teichmann, Jane Clarke and Christopher M. Dobson Nature438, 878–881
(08 December 2005); doi:10.1038/nature04195
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article mPins modulates PSD-95 and SAP102 trafficking and influences NMDA receptor surface expression
Nathalie Sans, Philip Y. Wang, Quansheng Du, Ronald S. Petralia, Ya-Xian Wang, Sajan Nakka, Joe B. Blumer, Ian G. Macara and Robert J. Wenthold Nature Cell Biology7, 1179–1190
(December 2005); doi:10.1038/ncb1325
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news and views Pins for spines
Juergen A. Knoblich Nature Cell Biology7, 1157–1158
(December 2005); doi:10.1038/ncb1205-1057
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letter Endocytic control of epithelial polarity and proliferation in Drosophila
Han Lu and David Bilder Nature Cell Biology7, 1232–1239
(December 2005); doi:10.1038/ncb1324
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article The Tim-3 ligand galectin-9 negatively regulates T helper type 1 immunity
Chen Zhu, Ana C Anderson, Anna Schubart, Huabao Xiong, Jaime Imitola, Samia J Khoury, Xin Xiao Zheng, Terry B Strom and Vijay K Kuchroo Nature Immunology6, 1245–1252
(December 2005); doi:10.1038/ni1271
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article Inhibiting Stat3 signaling in the hematopoietic system elicits multicomponent antitumor immunity
Marcin Kortylewski, Maciej Kujawski, Tianhong Wang, Sheng Wei, Shumin Zhang, Shari Pilon-Thomas, Guilian Niu, Heidi Kay, James Mulé, William G Kerr, Richard Jove, Drew Pardoll and Hua Yu Nature Medicine11, 1314–1321
(December 2005); doi:10.1038/nm1325
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article Regression of abdominal aortic aneurysm by inhibition of c-Jun N-terminal kinase
Koichi Yoshimura, Hiroki Aoki, Yasuhiro Ikeda, Kozo Fujii, Norio Akiyama, Akira Furutani, Yoshinobu Hoshii, Nobuyuki Tanaka, Romeo Ricci, Tokuhiro Ishihara, Kensuke Esato, Kimikazu Hamano and Masunori Matsuzaki Nature Medicine11, 1330–1338
(December 2005); doi:10.1038/nm1335
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news and views Aneurysm treatments expand
Robert W Thompson Nature Medicine11, 1279–1281
(December 2005); doi:10.1038/nm1205-1279
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brief communication Autoimmune-associated lymphoid tyrosine phosphatase is a gain-of-function variant
Torkel Vang, Mauro Congia, Maria Doloretta Macis, Lucia Musumeci, Valeria Orrú, Patrizia Zavattari, Konstantina Nika, Lutz Tautz, Kjetil Taskén, Francesco Cucca, Tomas Mustelin and Nunzio Bottini Nature Genetics37, 1317–1319
(December 2005); doi:10.1038/ng1673
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news and views Gaining insight into PTPN22 and autoimmunity
Peter K Gregersen Nature Genetics37, 1300–1302
(December 2005); doi:10.1038/ng1205-1300
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article Regulation of neuronal morphology and function by the tumor suppressors Tsc1 and Tsc2
Sohail F Tavazoie, Veronica A Alvarez, Dennis A Ridenour, David J Kwiatkowski and Bernardo L Sabatini Nature Neuroscience8, 1727–1734
(December 2005); doi:10.1038/nn1566
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review article Signalling in development: Bone morphogenetic protein signalling and vertebrate nervous system development
Aimin Liu and Lee A. Niswander Nature Reviews Neuroscience6, 945–954
(December 2005); doi:10.1038/nrn1805
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article High-throughput screening of effective siRNAs from RNAi libraries delivered via bacterial invasion
Hui-Fen Zhao, Denis L'Abbé, Normand Jolicoeur, Meiqun Wu, Zhen Li, Zhenbao Yu and Shi-Hsiang Shen Nature Methods2, 967–973
(December 2005); doi:10.1038/nmeth812
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letter Glyoxalase 1 and glutathione reductase 1 regulate anxiety in mice
Iiris Hovatta, Richard S. Tennant, Robert Helton, Robert A. Marr, Oded Singer, Jeffrey M. Redwine, Julie A. Ellison, Eric E. Schadt, Inder M. Verma, David J. Lockhart and Carrolee Barlow Nature438, 662–666
(01 December 2005); doi:10.1038/nature04250
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letter The microRNA miR-196 acts upstream of Hoxb8 and Shh in limb development
Eran Hornstein, Jennifer H. Mansfield, Soraya Yekta, Jimmy Kuang-Hsien Hu, Brian D. Harfe, Michael T. McManus, Scott Baskerville, David P. Bartel and Clifford J. Tabin Nature438, 671–674
(01 December 2005); doi:10.1038/nature04138
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letter Endophilin and CtBP/BARS are not acyl transferases in endocytosis or Golgi fission
Jennifer L. Gallop, P. Jonathan G. Butler and Harvey T. McMahon Nature438, 675–678
(01 December 2005); doi:10.1038/nature04136
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letter Global analysis of protein phosphorylation in yeast
Jason Ptacek, Geeta Devgan, Gregory Michaud, Heng Zhu, Xiaowei Zhu, Joseph Fasolo, Hong Guo, Ghil Jona, Ashton Breitkreutz, Richelle Sopko, Rhonda R. McCartney, Martin C. Schmidt, Najma Rachidi, Soo-Jung Lee, Angie S. Mah, Lihao Meng, Michael J. R. Stark, David F. Stern, Claudio De Virgilio, Mike Tyers, Brenda Andrews, Mark Gerstein, Barry Schweitzer, Paul F. Predki and Michael Snyder Nature438, 679–684
(01 December 2005); doi:10.1038/nature04187
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letter The APC/C and CBP/p300 cooperate to regulate transcription and cell-cycle progression
Andrew S. Turnell, Grant S. Stewart, Roger J. A. Grand, Susan M. Rookes, Ashley Martin, Hiroyuki Yamano, Stephen J. Elledge and Phillip H. Gallimore Nature438, 690–695
(01 December 2005); doi:10.1038/nature04151
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letter RNA-dependent integrin α3 protein localization regulated by the Muscleblind-like protein MLP1
Yair Adereth, Vincent Dammai, Nurgun Kose, Runzhao Li and Tien Hsu Nature Cell Biology7, 1240–1247
(December 2005); doi:10.1038/ncb1335
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news and views Moving with Muscleblind
Goncalo Rebelo de Andrade and Ralf-Peter Jansen Nature Cell Biology7, 1155–1156
(December 2005); doi:10.1038/ncb1205-1055
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review article Developmental Cell Biology: Cleavage Pattern and Emerging Asymmetry of the Mouse Embryo
Magdalena Zernicka-Goetz Nature Reviews Molecular Cell Biology6, 919–928
(December 2005); doi:10.1038/nrm1782
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article Newly generated T cell receptor microclusters initiate and sustain T cell activation by recruitment of Zap70 and SLP-76
Tadashi Yokosuka, Kumiko Sakata-Sogawa, Wakana Kobayashi, Michio Hiroshima, Akiko Hashimoto-Tane, Makio Tokunaga, Michael L Dustin and Takashi Saito Nature Immunology6, 1253–1262
(December 2005); doi:10.1038/ni1272
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news and views Microclusters initiate and sustain T cell signaling
Alain Trautmann Nature Immunology6, 1213–1214
(December 2005); doi:10.1038/ni1205-1213
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article The antioxidant function of the p53 tumor suppressor
Anna A Sablina, Andrei V Budanov, Galina V Ilyinskaya, Larissa S Agapova, Julia E Kravchenko and Peter M Chumakov Nature Medicine11, 1306–1313
(December 2005); doi:10.1038/nm1320
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review article Statins and cancer prevention
Marie-France Demierre , Peter D. R. Higgins , Stephen B. Gruber, Ernest Hawk and Scott M. Lippman Nature Reviews Cancer5, 930–942
(December 2005); doi:10.1038/nrc1751
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brief communication Inherited susceptibility to lung cancer may be associated with the T790M drug resistance mutation in EGFR
Daphne W Bell, Ira Gore, Ross A Okimoto, Nadia Godin-Heymann, Raffaella Sordella, Roseann Mulloy, Sreenath V Sharma, Brian W Brannigan, Gayatry Mohapatra, Jeff Settleman and Daniel A Haber Nature Genetics37, 1315–1316
(December 2005); doi:10.1038/ng1671
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article NMDA receptors regulate developmental gap junction uncoupling via CREB signaling
Harsha Arumugam, Xinhuai Liu, Paul J Colombo, Roderick A Corriveau and Andrei B Belousov Nature Neuroscience8, 1720–1726
(December 2005); doi:10.1038/nn1588
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news and views Flipping the switch from electrical to chemical communication
Karl Kandler and Edda Thiels Nature Neuroscience8, 1633–1634
(December 2005); doi:10.1038/nn1205-1633
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review article Exploiting the PI3K/AKT Pathway for Cancer Drug Discovery
Bryan T. Hennessy, Debra L. Smith, Prahlad T. Ram, Yiling Lu and Gordon B. Mills Nature Reviews Drug Discovery4, 988–1004
(December 2005); doi:10.1038/nrd1902
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brief communication Positional proteomics: selective recovery and analysis of N-terminal proteolytic peptides
Lucy McDonald, Duncan H L Robertson, Jane L Hurst and Robert J Beynon Nature Methods2, 955–957
(December 2005); doi:10.1038/nmeth811
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