The Research Library categorizes, and provides access to, all recent signaling-related research published in the Nature Publishing Group journals. The selection is deliberately broad to facilitate access to all research impacting on the signaling community. Both primary research and review articles are included, as are 'News and Views' articles.
Click here for free access to the 'Featured Articles' section, with new articles every week.
letter Tyrosine kinase receptor RET is a key regulator of Peyer's Patch organogenesis
Henrique Veiga-Fernandes, Mark C. Coles, Katie E. Foster, Amisha Patel, Adam Williams, Dipa Natarajan, Amanda Barlow, Vassilis Pachnis & Dimitris Kioussis Nature446, 547–551
(29 March 2007); doi:10.1038/nature05597
| Summary | Full Text (HTML / PDF) |
letter Epithelial-cell-intrinsic IKK-β expression regulates intestinal immune homeostasis
Colby Zaph, Amy E. Troy, Betsy C. Taylor, Lisa D. Berman-Booty, Katherine J. Guild, Yurong Du, Evan A. Yost, Achim D. Gruber, Michael J. May, Florian R. Greten, Lars Eckmann, Michael Karin & David Artis Nature446, 552–556
(29 March 2007); doi:10.1038/nature05590
| Summary | Full Text (HTML / PDF) |
letter Epithelial NEMO links innate immunity to chronic intestinal inflammation
Arianna Nenci, Christoph Becker, Andy Wullaert, Ralph Gareus, Geert van Loo, Silvio Danese, Marion Huth, Alexei Nikolaev, Clemens Neufert, Blair Madison, Deborah Gumucio, Markus F. Neurath & Manolis Pasparakis Nature446, 557–561
(29 March 2007); doi:10.1038/nature05698
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letter Dioxin receptor is a ligand-dependent E3 ubiquitin ligase
Fumiaki Ohtake, Atsushi Baba, Ichiro Takada, Maiko Okada, Kei Iwasaki, Hiromi Miki, Sayuri Takahashi, Alexander Kouzmenko, Keiko Nohara, Tomoki Chiba, Yoshiaki Fujii-Kuriyama & Shigeaki Kato Nature446, 562–566
(29 March 2007); doi:10.1038/nature05683
| Summary | Full Text (HTML / PDF) |
letter Structure of the yeast polarity protein Sro7 reveals a SNARE regulatory mechanism
Douglas A. Hattendorf, Anna Andreeva, Akanksha Gangar, Patrick J. Brennwald & William I. Weis Nature446, 567–571
(29 March 2007); doi:10.1038/nature05635
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article Constitutive RelA activation mediated by Nkx3.2 controls chondrocyte viability
Minsun Park, Yeryoung Yong, Seung-Won Choi, Jae Hwan Kim, Jong Eun Lee & Dae-Won Kim Nature Cell Biology9, 287–298
(March 2007); doi:10.1038/ncb1538
| Summary | Full Text (HTML / PDF) |
article Myosin IIA regulates cell motility and actomyosin—microtubule crosstalk
Sharona Even-Ram, Andrew D. Doyle, Mary Anne Conti, Kazue Matsumoto, Robert S. Adelstein & Kenneth M. Yamada Nature Cell Biology9, 299–309
(March 2007); doi:10.1038/ncb1540
| Summary | Full Text (HTML / PDF) |
letter Intrinsic ubiquitination activity of PCAF controls the stability of the oncoprotein Hdm2
Laëtitia K. Linares, Rosemary Kiernan, Robinson Triboulet, Christine Chable-Bessia, Daniel Latreille, Olivier Cuvier, Matthieu Lacroix, Laurent Le Cam, Olivier Coux & Monsef Benkirane Nature Cell Biology9, 331–338
(March 2007); doi:10.1038/ncb1545
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review Molecular mechanism of the nuclear protein import cycle
Murray Stewart Nature Reviews Molecular Cell Biology8, 195–208
(March 2007); doi:10.1038/nrm2114
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article DCs metabolize sunlight-induced vitamin D3 to 'program' T cell attraction to the epidermal chemokine CCL27
Hekla Sigmundsdottir, Junliang Pan, Gudrun F Debes, Carsten Alt, Aida Habtezion, Dulce Soler & Eugene C Butcher Nature Immunology8, 285–293
(March 2007); doi:10.1038/ni1433
| Summary | Full Text (HTML / PDF) |
perspective The dynamic co-evolution of memory and regulatory CD4+ T cells in the periphery
Arne N. Akbar, Milica Vukmanovic-Stejic, Leonie S. Taams and Derek C. Macallan Nature Reviews Immunology7, 231–237
(March 2007); doi:10.1038/nri2037
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article Hdac2 regulates the cardiac hypertrophic response by modulating Gsk3β activity
Chinmay M Trivedi, Yang Luo, Zhan Yin, Maozhen Zhang, Wenting Zhu, Tao Wang, Thomas Floss, Martin Goettlicher, Patricia Ruiz Noppinger, Wolfgang Wurst, Victor A Ferrari, Charles S Abrams, Peter J Gruber & Jonathan A Epstein Nature Medicine13, 324–331
(March 2007); doi:10.1038/nm1552
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article IFN-γ mediates CD4+ T-cell loss and impairs secondary antitumor responses after successful initial immunotherapy
Vanessa Berner, Haiyan Liu, Qing Zhou, Kory L Alderson, Kai Sun, Jonathan M Weiss, Timothy C Back, Dan L Longo, Bruce R Blazar, Robert H Wiltrout, Lisbeth A Welniak, Doug Redelman & William J Murphy Nature Medicine13, 354–360
(March 2007); doi:10.1038/nm1554
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news and views Vaccine leads to memory loss
John B A G Haanen & Ton N M Schumacher Nature Medicine13, 248–250
(March 2007); doi:10.1038/nm0307-248
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review Epidermal growth factor receptor mutations in lung cancer
Sreenath V. Sharma, Daphne W. Bell, Jeffrey Settleman & Daniel A. Haber Nature Reviews Cancer7, 169–181
(March 2007); doi:10.1038/nrc2088
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review The Salvador–Warts–Hippo pathway — an emerging tumour-suppressor network
Kieran Harvey & Nicolas Tapon Nature Reviews Cancer7, 182–191
(March 2007); doi:10.1038/nrc2070
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article Protein tyrosine phosphatase 1B deficiency or inhibition delays ErbB2-induced mammary tumorigenesis and protects from lung metastasis
Sofi G Julien, Nadia Dubé, Michelle Read, Janice Penney, Marilene Paquet, Yongxin Han, Brian P Kennedy, William J Muller & Michel L Tremblay Nature Genetics39, 338–346
(March 2007); doi:10.1038/ng1963
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perspective Beyond standardization: dynamic software infrastructures for systems biology
Morris A. Swertz and Ritsert C. Jansen Nature Reviews Genetics8, 235–243
(March 2007); doi:10.1038/nrg2048
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article cAMP oscillations and retinal activity are permissive for ephrin signaling during the establishment of the retinotopic map
Xavier Nicol, Sylvie Voyatzis, Aude Muzerelle, Nicolas Narboux-Nême, Thomas C Südhof, Richard Miles & Patricia Gaspar Nature Neuroscience10, 340–347
(March 2007); doi:10.1038/nn1842
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article Grb4 and GIT1 transduce ephrinB reverse signals modulating spine morphogenesis and synapse formation
Inmaculada Segura, Clara L Essmann, Stefan Weinges & Amparo Acker-Palmer Nature Neuroscience10, 301–310
(March 2007); doi:10.1038/nn1858
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review Neuronal polarity: from extracellular signals to intracellular mechanisms
Nariko Arimura and Kozo Kaibuchi Nature Reviews Neuroscience8, 194–205
(March 2007); doi:10.1038/nrn2056
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article Live dynamic imaging of caveolae pumping targeted antibody rapidly and specifically across endothelium in the lung
Phil Oh, Per Borgström, Halina Witkiewicz, Yan Li, Bengt J Borgström, Adrian Chrastina, Koji Iwata, Kurt R Zinn, Richard Baldwin, Jacqueline E Testa & Jan E Schnitzer Nature Biotechnology25, 327–337
(March 2007); doi:10.1038/nbt1292
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article The gene encoding the splicing factor SF2/ASF is a proto-oncogene
Rotem Karni, Elisa de Stanchina, Scott W Lowe, Rahul Sinha, David Mu & Adrian R Krainer Nature Structural & Molecular Biology14, 185–193
(March 2007); doi:10.1038/nsmb1209
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news and views Splicing oncogenes
Anchang Hu & Xiang-Dong Fu Nature Structural & Molecular Biology14, 174–175
(March 2007); doi:10.1038/nsmb0307-174
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article Ubc9 fusion-directed SUMOylation (UFDS): a method to analyze function of protein SUMOylation
Astrid Jakobs, Jesko Koehnke, Fabian Himstedt, Martin Funk, Bernhard Korn, Matthias Gaestel & Rainer Niedenthal Nature Methods4, 245–250
(March 2007); doi:10.1038/nmeth1006
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article TRPM8 voltage sensor mutants reveal a mechanism for integrating thermal and chemical stimuli
Thomas Voets, Grzegorz Owsianik, Annelies Janssens, Karel Talavera and Bernd Nilius Nature Chemical Biology3, 174–182
(March 2007); doi:10.1038/nchembio862
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letter Vitamin B6 conjugation to nuclear corepressor RIP140 and its role in gene regulation
M D Mostaqul Huq, Nien-Pei Tsai, Ya-Ping Lin, LeeAnn Higgins and Li-Na Wei Nature Chemical Biology3, 161–165
(March 2007); doi:10.1038/nchembio861
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letter Relating ligand binding to activation gating in CNGA2 channels
Christoph Biskup, Jana Kusch, Eckhard Schulz, Vasilica Nache, Frank Schwede, Frank Lehmann, Volker Hagen and Klaus Benndorf Nature446, 440–443
(22 March 2007); doi:10.1038/nature05596
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letter p53-induced inhibition of Hif-1 causes cardiac dysfunction during pressure overload
Masanori Sano, Tohru Minamino, Haruhiro Toko, Hideyuki Miyauchi, Masayuki Orimo, Yingjie Qin, Hiroshi Akazawa, Kaoru Tateno, Yosuke Kayama, Mutsuo Harada, Ippei Shimizu, Takayuki Asahara, Hirofumi Hamada, Shuhei Tomita, Jeffrey D. Molkentin, Yunzeng Zou and Issei Komuro Nature446, 444–448
(22 March 2007); doi:10.1038/nature05602
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article Caspase-11 regulates cell migration by promoting Aip1—Cofilin-mediated actin depolymerization
Juying Li, William M. Brieher, M. Lucila Scimone, Shin Jung Kang, Hong Zhu, Helen Yin, Ulrich H. von Andrian, Timothy Mitchison & Junying Yuan Nature Cell Biology9, 276–286
(March 2007); doi:10.1038/ncb1541
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news and views Moving away from death: when caspase-11 meets cofilin
Maryse Bailly Nature Cell Biology9, 245–246
(March 2007); doi:10.1038/ncb0307-245
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review In search of partners: linking extracellular proteases to substrates
Christopher M. Overall and Carl P. Blobel Nature Reviews Molecular Cell Biology8, 245–257
(March 2007); doi:10.1038/nrm2120
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article Epithelial cells trigger frontline immunoglobulin class switching through a pathway regulated by the inhibitor SLPI
Weifeng Xu, Bing He, April Chiu, Amy Chadburn, Meimei Shan, Malwina Buldys, Aihao Ding, Daniel M Knowles, Paul A Santini & Andrea Cerutti Nature Immunology8, 294–303
(March 2007); doi:10.1038/ni1434
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news and views Local sentries for class switching
Michael McHeyzer-Williams Nature Immunology8, 230–232
(March 2007); doi:10.1038/ni0307-230
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article Increased IgE-dependent mast cell activation and anaphylactic responses in mice lacking the calcium-activated nonselective cation channel TRPM4
Rudi Vennekens, Jenny Olausson, Marcel Meissner, Wilhelm Bloch, Ilka Mathar, Stephan E Philipp, Frank Schmitz, Petra Weissgerber, Bernd Nilius, Veit Flockerzi & Marc Freichel Nature Immunology8, 312–320
(March 2007); doi:10.1038/ni1441
| Summary | Full Text (HTML / PDF) |
commentary CC chemokines and protective immunity: insights gained from mother-to-child transmission of HIV
Caroline T Tiemessen & Louise Kuhn Nature Immunology8, 219–222
(March 2007); doi:10.1038/ni0307-219
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review Cooperation of Toll-like receptor signals in innate immune defence
Giorgio Trinchieri and Alan Sher Nature Reviews Immunology7, 179–190
(March 2007); doi:10.1038/nri2038
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review Fetal B-cell lymphopoiesis and the emergence of B-1-cell potential
Kenneth Dorshkind and Encarnacion Montecino-Rodriguez Nature Reviews Immunology7, 213–219
(March 2007); doi:10.1038/nri2019
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article Adrenal GRK2 upregulation mediates sympathetic overdrive in heart failure
Anastasios Lymperopoulos, Giuseppe Rengo, Hajime Funakoshi, Andrea D Eckhart & Walter J Koch Nature Medicine13, 315–323
(March 2007); doi:10.1038/nm1553
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news and views Long-distance affair with adrenal GRK2 hangs up heart failure
Stephen B Liggett Nature Medicine13, 246–248
(March 2007); doi:10.1038/nm0307-246
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article ASC-J9 ameliorates spinal and bulbar muscular atrophy phenotype via degradation of androgen receptor
Zhiming Yang, Yu-Jia Chang, I-Chen Yu, Shuyuan Yeh, Cheng-Chia Wu, Hiroshi Miyamoto, Diane E Merry, Gen Sobue, Lu-Min Chen, Shu-Shi Chang & Chawnshang Chang Nature Medicine13, 348–353
(March 2007); doi:10.1038/nm1547
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review Inhibiting transient protein—protein interactions: lessons from the Cdc25 protein tyrosine phosphatases
Johannes Rudolph Nature Reviews Cancer7, 202–211
(March 2007); doi:10.1038/nrc2087
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letter Complete inactivation of DNMT1 leads to mitotic catastrophe in human cancer cells
Taiping Chen, Sarah Hevi, Frédérique Gay, Naomi Tsujimoto, Timothy He, Bailin Zhang, Yoshihide Ueda & En Li Nature Genetics7, 391–396
(March 2007); doi:10.1038/ng1982
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news and views DNMT1 knockout delivers a strong blow to genome stability and cell viability
Kevin D Brown & Keith D Robertson Nature Genetics7, 289–290
(March 2007); doi:10.1038/ng0307-289
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review Light-regulated transcriptional networks in higher plants
Yuling Jiao, On Sun Lau and Xing Wang Deng Nature Reviews Genetics8, 217–230
(March 2007); doi:10.1038/nrg2049
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article Alternative splicing controls G protein—dependent inhibition of N-type calcium channels in nociceptors
Jesica Raingo, Andrew J Castiglioni & Diane Lipscombe Nature Neurobiology10, 285–292
(March 2007); doi:10.1038/nn1848
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news and views Calcium channels diversify their signaling portfolio
Stephen R Ikeda & Kathleen Dunlap Nature Neurobiology10, 269–271
(March 2007); doi:10.1038/nn0307-269
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review Neuronal calcium sensor proteins: generating diversity in neuronal Ca2+ signalling
Robert D. Burgoyne Nature Reviews Neurobiology8, 182–193
(March 2007); doi:10.1038/nrn2093
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review High-throughput electronic biology: mining information for drug discovery
William Loging, Lee Harland and Bryn Williams-Jones Nature Reviews Drug Discovery6, 220–230
(March 2007); doi:10.1038/nrd2265
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news and views How to gate an ion channel: lessons from MthK
Sudha Chakrapani & Eduardo Perozo Nature Structural & Molecular Biology14, 180–182
(March 2007); doi:10.1038/nsmb0307-180
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letter A clickable inhibitor reveals context-dependent autoactivation of p90 RSK
Michael S Cohen, Haralambos Hadjivassiliou and Jack Taunton Nature Chemical Biology3, 156–160
(March 2007); doi:10.1038/nchembio859
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news and views A RSK kinase inhibitor reporting its selectivity in vivo
Morten Frödin Nature Chemical Biology3, 138–139
(March 2007); doi:10.1038/nchembio0307-138
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review Virus trafficking — learning from single-virus tracking
Boerries Brandenburg and Xiaowei Zhuang Nature Reviews Microbiology5, 197–208
(March 2007); doi:10.1038/nrmicro1615
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letter A recurrent mutation in PALB2 in Finnish cancer families
Hannele Erkko, Bing Xia, Jenni Nikkilä, Johanna Schleutker, Kirsi Syrjäkoski, Arto Mannermaa, Anne Kallioniemi, Katri Pylkäs, Sanna-Maria Karppinen, Katrin Rapakko, Alexander Miron, Qing Sheng, Guilan Li, Henna Mattila, Daphne W. Bell, Daniel A. Haber, Mervi Grip, Mervi Reiman, Arja Jukkola-Vuorinen, Aki Mustonen, Juha Kere, Lauri A. Aaltonen, Veli-Matti Kosma, Vesa Kataja, Ylermi Soini, Ronny I. Drapkin, David M. Livingston and Robert Winqvist Nature446, 316–319
(15 March 2007); doi:10.1038/nature05609
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letter A Hedgehog- and Antennapedia-dependent niche maintains Drosophila haematopoietic precursors
Lolitika Mandal, Julian A. Martinez-Agosto, Cory J. Evans, Volker Hartenstein and Utpal Banerjee Nature446, 320–324
(15 March 2007); doi:10.1038/nature05585
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letter Control of blood cell homeostasis in Drosophila larvae by the posterior signalling centre
Joanna Krzemien, Laurence Dubois, Rami Makki, Marie Meister, Alain Vincent and Michèle Crozatier Nature446, 325–328
(15 March 2007); doi:10.1038/nature05650
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letter A ubiquitin ligase transfers preformed polyubiquitin chains from a conjugating enzyme to a substrate
Wei Li, Daqi Tu, Axel T. Brunger and Yihong Ye Nature446, 333–337
(15 March 2007); doi:10.1038/nature05542
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letter Structure and function of the histone chaperone CIA/ASF1 complexed with histones H3 and H4
Ryo Natsume, Masamitsu Eitoku, Yusuke Akai, Norihiko Sano, Masami Horikoshi and Toshiya Senda Nature446, 338–341
(15 March 2007); doi:10.1038/nature05613
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letter 14-3-3σ controls mitotic translation to facilitate cytokinesis
Erik W. Wilker, Marcel A. T. M. van Vugt, Steven A. Artim, Paul H. Huang, Christian P. Petersen, H. Christian Reinhardt, Yun Feng, Phillip A. Sharp, Nahum Sonenberg, Forest M. White and Michael B. Yaffe Nature446, 329–332
(15 March 2007); doi:10.1038/nature05584
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news and views Cell biology: Lost in mitotic translation
Anthony Wynshaw-Boris Nature446, 274–275
(15 March 2007); doi:10.1038/446274a
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letter Insulin signalling to mTOR mediated by the Akt/PKB substrate PRAS40
Emilie Vander Haar, Seong-il Lee, Sricharan Bandhakavi, Timothy J. Griffin & Do-Hyung Kim Nature Cell Biology9, 316–323
(March 2007); doi:10.1038/ncb1547
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review [Ca2+]i signalling in sperm — making the most of what you've got
Stephen Publicover, Claire V. Harper & Christopher Barratt Nature Cell Biology9, 235–242
(March 2007); doi:10.1038/ncb0307-235
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news and views Stressed marrow: FoxOs stem tumour growth
Paul J. Coffer & Boudewijn M. T. Burgering Nature Cell Biology9, 251–253
(March 2007); doi:10.1038/ncb0307-251
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review Emerging roles of nuclear protein phosphatases
Greg B. G. Moorhead, Laura Trinkle-Mulcahy and Annegret Ulke-Lemée Nature Reviews Molecular Cell Biology8, 234–244
(March 2007); doi:10.1038/nrm2126
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article A T cell receptor flattens a bulged antigenic peptide presented by a major histocompatibility complex class I molecule
Fleur E Tynan, Hugh H Reid, Lars Kjer-Nielsen, John J Miles, Matthew C J Wilce, Lyudmila Kostenko, Natalie A Borg, Nicholas A Williamson, Travis Beddoe, Anthony W Purcell, Scott R Burrows, James McCluskey & Jamie Rossjohn Nature Immunology8, 268–276
(March 2007); doi:10.1038/ni1432
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article Secretory cytotoxic granule maturation and exocytosis require the effector protein hMunc13-4
Mickaël M Ménager, Gaël Ménasché, Maryse Romao, Perrine Knapnougel, Chen-Hsuan Ho, Mériem Garfa, Graça Raposo, Jérôme Feldmann, Alain Fischer & Geneviève de Saint Basile Nature Immunology8, 257–267
(March 2007); doi:10.1038/ni1431
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article Maintenance of the Foxp3-dependent developmental program in mature regulatory T cells requires continued expression of Foxp3
Luke M Williams & Alexander Y Rudensky Nature Immunology8, 277–284
(March 2007); doi:10.1038/ni1437
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news and views Regulatory T cell development: is Foxp3 the decider?
Tyler J Curiel Nature Medicine13, 250–253
(March 2007); doi:10.1038/nm0307-250
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news and views Cracking the cytokine code in psoriasis
Brian J Nickoloff Nature Medicine13, 242–244
(March 2007); doi:10.1038/nm0307-242
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news and views Skin safety
Charlotte Schubert Nature Medicine13, 244
(March 2007); doi:10.1038/nm0307-244
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letter A common coding variant in CASP8 is associated with breast cancer risk
Angela Cox et al. Nature Genetics39, 352 - 358
(March 2007); doi:10.1038/ng1981
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letter High-throughput oncogene mutation profiling in human cancer
Roman K Thomas et al. Nature Genetics39, 347 - 351
(March 2007); doi:10.1038/ng1975
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news and views The devil is in the DNA
Stephen J Chanock & Gilles Thomas Nature Genetics39, 283 - 284
(March 2007); doi:10.1038/ng0307-283
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article Vesicular glutamate release from axons in white matter
Maria Kukley, Estibaliz Capetillo-Zarate & Dirk Dietrich Nature Neuroscience10, 311 - 320
(March 2007); doi:10.1038/nn1850
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news and views Surprising synapses deep in the brain
Vittorio Gallo Nature Neuroscience10, 267 - 269
(March 2007); doi:10.1038/nn0307-267
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brief communication Direct activation of the ion channel TRPA1 by Ca2+
Sandra Zurborg, Brian Yurgionas, Julia A Jira, Ombretta Caspani & Paul A Heppenstall Nature Neuroscience10, 277 - 279
(March 2007); doi:10.1038/nn1843
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article An integrated mass spectrometric and computational framework for the analysis of protein interaction networks
Oliver Rinner, Lukas N. Mueller, Martin Hubálek, Markus Müller, Matthias Gstaiger & Ruedi Aebersold Nature Biotechnology25, 345 - 352
(March 2007); doi:10.1038/nbt1289
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article Tumor suppressor p53 restricts Ras stimulation of RhoA and cancer cell motility
Mingxuan Xia & Hartmut Land Nature Biotechnology14, 215 - 223
(March 2007); doi:10.1038/nsmb1208
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brief communication Small-molecule regulation of zebrafish gene expression
Hanife Esengil, Vicky Chang, John K Mich and James K Chen Nature Chemical Biology3, 154 - 155
(March 2007); doi:10.1038/nchembio858
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news and views Small-molecule switch for zebrafish gene expression
Young-Tae Chang Nature Chemical Biology3, 135 - 136
(March 2007); doi:10.1038/nchembio0307-135
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scientific report Structure of the ubiquitin-binding zinc finger domain of human DNA Y-polymeraseη
Martha G Bomar, Ming-Tao Pai, Shiou-Ru Tzeng, Shawn Shun-Cheng Li & Pei Zhou EMBO reports8, 247 – 251
(March 2007); doi:10.1038/sj.embor.7400901
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scientific report Interferons induce tyrosine phosphorylation of the eIF2alpha kinase PKR through activation of Jak1 and Tyk2
Qiaozhu Su, Shuo Wang, Dionissios Baltzis, Li-Ke Qu, Jennifer F Raven, Suiyang Li, Andrew Hoi-Tao Wong & Antonis E Koromilas EMBO reports8, 265 – 270
(March 2007); doi:10.1038/sj.embor.7400891
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letter A single type of progenitor cell maintains normal epidermis
Elizabeth Clayton, David P. Doupé, Allon M. Klein, Douglas J. Winton, Benjamin D. Simons and Philip H. Jones Nature446, 185–189
(8 March 2007); doi:10.1038/nature05574
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letter The epidermis both drives and restricts plant shoot growth
Sigal Savaldi-Goldstein, Charles Peto and Joanne Chory Nature446, 199–202
(8 March 2007); doi:10.1038/nature05618
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news and views Plant biology: The force from without
Ben Scheres Nature446, 151–152
(8 March 2007); doi:10.1038/446151a
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letter A cytosolic trans-activation domain essential for ammonium uptake
D. Loqué, S. Lalonde, L. L. Looger, N. von Wirén and W. B. Frommer Nature446, 195–198
(8 March 2007); doi:10.1038/nature05579
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letter C5L2 is critical for the biological activities of the anaphylatoxins C5a and C3a
Nien-Jung Chen, Christine Mirtsos, Daniel Suh, Yong-Chen Lu, Wen-Jye Lin, Colin McKerlie, Taeweon Lee, Helene Baribault, Hui Tian and Wen-Chen Yeh Nature446, 203–207
(8 March 2007); doi:10.1038/nature05559
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letter Structure of an ABC transporter in complex with its binding protein
Kaspar Hollenstein, Dominik C. Frei and Kaspar P. Locher Nature446, 213–216
(8 March 2007); doi:10.1038/nature05626
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article Patterns of somatic mutation in human cancer genomes
Christopher Greenman et al. Nature446, 153–158
(8 March 2007); doi:10.1038/nature05610
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news and views Cancer: Drivers and passengers
Daniel A. Haber and Jeff Settleman Nature446, 145–146
(8 March 2007); doi:10.1038/446145a
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letter Growth factor-induced MAPK network topology shapes Erk response determining PC-12 cell fate
Silvia D. M. Santos, Peter J. Verveer & Philippe I. H. Bastiaens Nature Cell Biology9, 324–330
(March 2007); doi:10.1038/ncb1543
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news and views Untangling the signalling wires
Boris N. Kholodenko Nature Cell Biology9, 247–249
(March 2007); doi:10.1038/ncb0307-247
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article CIPC is a mammalian circadian clock protein without invertebrate homologues
Wen-Ning Zhao, Nikolay Malinin, Fu-Chia Yang, David Staknis, Nicholas Gekakis, Bert Maier, Silke Reischl, Achim Kramer & Charles J. Weitz Nature Cell Biology9, 268–275
(March 2007); doi:10.1038/ncb1539
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review Matrix metalloproteinases and the regulation of tissue remodelling
Andrea Page-McCaw, Andrew J. Ewald and Zena Werb Nature Reviews Molecular Cell Biology8, 221–223
(March 2007); doi:10.1038/nrm2125
| Summary | Full Text (HTML / PDF) |
review MAPK phosphatases — regulating the immune response
Yusen Liu, Edward G. Shepherd and Leif D. Nelin Nature Reviews Immunology7, 202–212
(March 2007); doi:10.1038/nri2035
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article β-cell ABCA1 influences insulin secretion, glucose homeostasis and response to thiazolidinedione treatment pp340
Liam R Brunham, Janine K Kruit, Terry D Pape, Jenelle M Timmins, Anne Q Reuwer, Zainisha Vasanji, Brad J Marsh, Brian Rodrigues, James D Johnson, John S Parks, C Bruce Verchere & Michael R Hayden Nature Medicine 13, 340–347
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letter Cross-talk and decision making in MAP kinase pathways
Megan N McClean, Areez Mody, James R Broach & Sharad Ramanathan Nature Genetics 39, 409–414
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news and views Shaping specificity in signaling networks
Réka Albert & Zoltán N Oltvai Nature Genetics 39, 286–287
(March 2007); doi:10.1038/ng0307-286
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analysis A human phenome-interactome network of protein complexes implicated in genetic disorders
Kasper Lage, E Olof Karlberg, Zenia M Størling, Páll Í Ólason, Anders G Pedersen, Olga Rigina, Anders M Hinsby, Zeynep Tümer, Flemming Pociot, Niels Tommerup, Yves Moreau & Søren Brunak Nature Biotechnology 25, 309–316
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brief communication Structure of a VEGF–VEGF receptor complex determined by electron microscopy
Claudia Ruch, Georgios Skiniotis, Michel O Steinmetz, Thomas Walz & Kurt Ballmer-Hofer Nature Structural & Molecular Biology 14, 249–250
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article CD38 is critical for social behaviour by regulating oxytocin secretion
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article MAPK-mediated bimodal gene expression and adaptive gradient sensing in yeast
Saurabh Paliwal, Pablo A. Iglesias, Kyle Campbell, Zoe Hilioti, Alex Groisman and Andre Levchenko Nature446, 46–51
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letter Chemical rescue of cleft palate and midline defects in conditional GSK-3β mice
Karen J. Liu, Joseph R. Arron, Kryn Stankunas, Gerald R. Crabtree and Michael T. Longaker Nature446, 79–82
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letter Transferrin receptor 1 is a cellular receptor for New World haemorrhagic fever arenaviruses
Sheli R. Radoshitzky, Jonathan Abraham, Christina F. Spiropoulou, Jens H. Kuhn, Dan Nguyen, Wenhui Li, Jane Nagel, Paul J. Schmidt, Jack H. Nunberg, Nancy C. Andrews, Michael Farzan and Hyeryun Choe Nature446, 92–96
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letter Gating pore current in an inherited ion channelopathy
Stanislav Sokolov, Todd Scheuer and William A. Catterall Nature446, 76–78
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news and views Physiology: Legacy of leaky channels
Richard Horn Nature446, 32–34
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news and views Cell biology: Aneuploidy and cancer
David Pellman Nature446, 38–39
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review The multiple faces of caveolae
Robert G. Parton and Kai Simons Nature Reviews Molecular Cell Biology8, 185–194
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article The adaptor Act1 is required for interleukin 17–dependent signaling associated with autoimmune and inflammatory disease
Youcun Qian, Caini Liu, Justin Hartupee, Cengiz Zubeyir Altuntas, Muhammet Fatih Gulen, Daniel Jane-wit, Jianhua Xiao, Yi Lu, Natalia Giltiay, Jinbo Liu, Tomasz Kordula, Qi-Wei Zhang, Bruce Vallance, Shadi Swaidani, Mark Aronica, Vincent K Tuohy, Thomas Hamilton & Xiaoxia Li Nature Immunology8, 247–256
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news and views Act1-ivating IL-17 inflammation
Christopher A Hunter Nature Immunology8, 232–234
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review The function of programmed cell death 1 and its ligands in regulating autoimmunity and infection
Arlene H Sharpe, E John Wherry, Rafi Ahmed & Gordon J Freeman Nature Immunology8, 239–245
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review PI3Kδ and PI3Kγ: partners in crime in inflammation in rheumatoid arthritis and beyond?
Christian Rommel, Montserrat Camps and Hong Ji Nature Reviews Immunology7, 191–201
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perspective Darwinian medicine: a case for cancer
Mel Greaves Nature Reviews Cancer7, 213–221
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review Strategies for silencing human disease using RNA interference
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article GDNF and GFRα1 promote formation of neuronal synapses by ligand-induced cell adhesion
Fernanda Ledda, Gustavo Paratcha, Tatiana Sandoval-Guzmán & Carlos F Ibáñez Nature Neuroscience10, 293–300
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article Glutamate exocytosis from astrocytes controls synaptic strength
Pascal Jourdain, Linda H Bergersen, Khaleel Bhaukaurally, Paola Bezzi, Mirko Santello, Maria Domercq, Carlos Matute, Fiorella Tonello, Vidar Gundersen & Andrea Volterra Nature Neuroscience10, 331–339
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news and views Astrocytes target presynaptic NMDA receptors to give synapses a boost
Rheinallt Parri & Vincenzo Crunelli Nature Neuroscience10, 271–273
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review Cell adhesion molecules: signalling functions at the synapse
Matthew B. Dalva, Andrew C. McClelland and Matthew S. Kayser Nature Reviews Neuroscience8, 206–220
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review The road to chromatin — nuclear entry of retroviruses
Youichi Suzuki and Robert Craigie Nature Reviews Microbiology5, 187–196
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article Activating gene expression in mammalian cells with promoter-targeted duplex RNAs
Bethany A Janowski, Scott T Younger, Daniel B Hardy, Rosalyn Ram, Kenneth E Huffman and David R Corey Nature Chemical Biology3, 166–173
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news and views Per2 has time on its side
Urs Albrecht Nature Chemical Biology3, 139–140
(March 2007); doi:10.1038/nchembio0307-139
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