The Research Library categorizes, and provides access to, all recent signaling-related research published in the Nature Publishing Group journals. The selection is deliberately broad to facilitate access to all research impacting on the signaling community. Both primary research and review articles are included, as are 'News and Views' articles.
Click here for free access to the 'Featured Articles' section, with new articles every week.
article OGG1 initiates age-dependent CAG trinucleotide expansion in somatic cells
Irina V. Kovtun, Yuan Liu, Magnar Bjoras, Arne Klungland, Samuel H. Wilson & Cynthia T. McMurray Nature447, 447–452
(24 May 2007); doi:10.1038/nature05778
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article Atomic structures of amyloid cross-β spines reveal varied steric zippers
Michael R. Sawaya, Shilpa Sambashivan, Rebecca Nelson, Magdalena I. Ivanova, Stuart A. Sievers, Marcin I. Apostol, Michael J. Thompson, Melinda Balbirnie, Jed J. W. Wiltzius, Heather T. McFarlane, Anders Ø. Madsen, Christian Riekel & David Eisenberg Nature447, 453–457
(24 May 2007); doi:10.1038/nature05695
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letter Aggregation and vesiculation of membrane proteins by curvature-mediated interactions
Benedict J. Reynwar, Gregoria Illya, Vagelis A. Harmandaris, Martin M. Müller, Kurt Kremer & Markus Deserno Nature447, 461–464
(24 May 2007); doi:10.1038/nature05840
| Summary | Full Text (HTML / PDF) |
letter An autopodial-like pattern of Hox expression in the fins of a basal actinopterygian fish
Marcus C. Davis, Randall D. Dahn & Neil H. Shubin Nature447, 473–476
(24 May 2007); doi:10.1038/nature05838
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letter Transcriptional coactivator PGC-1α integrates the mammalian clock and energy metabolism
Chang Liu, Siming Li, Tiecheng Liu, Jimo Borjigin & Jiandie D. Lin Nature447, 477–481
(24 May 2007); doi:10.1038/nature05767
| Summary | Full Text (HTML / PDF) |
letter Disulphide-isomerase-enabled shedding of tumour-associated NKG2D ligands
Brett K. Kaiser, Daesong Yim, I-Ting Chow, Segundo Gonzalez, Zhenpeng Dai, Henning H. Mann, Roland K. Strong, Veronika Groh & Thomas Spies Nature447, 482–486
(24 May 2007); doi:10.1038/nature05768
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letter Redox-mediated substrate recognition by Sdp1 defines a new group of tyrosine phosphatases
G. C. Fox, M. Shafiq, D. C. Briggs, P. P. Knowles, M. Collister, M. J. Didmon, V. Makrantoni, R. J. Dickinson, S. Hanrahan, N. Totty, M. J. R. Stark, S. M. Keyse & N. Q. McDonald Nature447, 487–492
(24 May 2007); doi:10.1038/nature05804
| Summary | Full Text (HTML / PDF) |
letter Experimental and theoretical study of mitotic spindle orientation
Manuel Théry, Andrea Jiménez-Dalmaroni, Victor Racine, Michel Bornens & Frank Jülicher Nature447, 493–496
(24 May 2007); doi:10.1038/nature05786
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letter The neural progenitor-specifying activity of FoxG1 is antagonistically regulated by CKI and FGF
Tarik Regad, Martin Roth, Nicholas Bredenkamp, Nicola Illing & Nancy Papalopulu Nature Cell Biology9, 531–540
(May 2007); doi:10.1038/ncb1573
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letter p53 gain-of-function cancer mutants induce genetic instability by inactivating ATM
Hoseok Song, Monica Hollstein & Yang Xu Nature Cell Biology9, 573–580
(May 2007); doi:10.1038/ncb1571
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news and views p53: a two-faced cancer gene
Michael B. Kastan & Elijahu Berkovich Nature Cell Biology9, 489–491
(May 2007); doi:10.1038/ncb0507-489
| Summary | Full Text (HTML / PDF) |
review Werner and Hutchinson–Gilford progeria syndromes: mechanistic basis of human progeroid diseases
Brian A. Kudlow, Brian K. Kennedy & Raymond J. Monnat, Jr Nature Reviews Molecular Cell Biology8, 394–404
(May 2007); doi:10.1038/nrm2161
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article Smad7 binds to the adaptors TAB2 and TAB3 to block recruitment of the kinase TAK1 to the adaptor TRAF2
Suntaek Hong, Seunghwan Lim, Allen G Li, Chan Lee, Youn Sook Lee, Eun-Kyung Lee, Seok Hee Park, Xiao-Jing Wang & Seong-Jin Kim Nature Immunology8, 504–513
(May 2007); doi:10.1038/ni1451
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news and views Smads keep TABs on inflammation
Rashu B Seth & Zhijian J Chen Nature Immunology8, 477–478
(May 2007); doi:10.1038/ni0507-477
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article A crucial function of SGT1 and HSP90 in inflammasome activity links mammalian and plant innate immune responses
Annick Mayor, Fabio Martinon, Thibaut De Smedt, Virginie Pétrilli & Jürg Tschopp Nature Immunology8, 497–503
(May 2007); doi:10.1038/ni1459
| Summary | Full Text (HTML / PDF) |
news and views Epithelial NF-κB maintains host gut microflora homeostasis
Yinon Ben-Neriah & Marc Schmidt-Supprian Nature Immunology8, 479–481
(May 2007); doi:10.1038/ni0507-479
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article Osteopontin has a crucial role in allergic airway disease through regulation of dendritic cell subsets
Georgina Xanthou, Themis Alissafi, Maria Semitekolou, Davina C M Simoes, Erasmia Economidou, Mina Gaga, Bart N Lambrecht, Clare M Lloyd & Vily Panoutsakopoulou Nature Medicine13, 570–578
(May 2007); doi:10.1038/nm1580
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news and views The bridge between dendritic cells and asthma
Mari L Shinohara & Harvey Cantor Nature Medicine13, 536–538
(May 2007); doi:10.1038/nm0507-536
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article Reverse signaling through GITR ligand enables dexamethasone to activate IDO in allergy
Ursula Grohmann, Claudia Volpi, Francesca Fallarino, Silvia Bozza, Roberta Bianchi, Carmine Vacca, Ciriana Orabona, Maria L Belladonna, Emira Ayroldi, Giuseppe Nocentini, Louis Boon, Francesco Bistoni, Maria C Fioretti, Luigina Romani, Carlo Riccardi & Paolo Puccetti Nature Medicine13, 579–586
(May 2007); doi:10.1038/nm1563
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article SIK1 is a class II HDAC kinase that promotes survival of skeletal myocytes
Rebecca Berdeaux, Naomi Goebel, Laura Banaszynski, Hiroshi Takemori, Thomas Wandless, G Diane Shelton & Marc Montminy Nature Medicine13, 597–603
(May 2007); doi:10.1038/nm1573
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review Laminin 332 in squamous-cell carcinoma
M. Peter Marinkovich Nature Reviews Cancer7, 370–380
(May 2007); doi:10.1038/nrc2089
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progress The Delta paradox: DLL4 blockade leads to more tumour vessels but less tumour growth
Gavin Thurston, Irene Noguera-Troise & George D. Yancopoulos Nature Reviews Cancer7, 327–331
(May 2007); doi:10.1038/nrc2130
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letter Serotonin and neuropeptide F have opposite modulatory effects on fly aggression
Herman A Dierick & Ralph J Greenspan Nature Genetics39, 678–682
(May 2007); doi:10.1038/ng2029
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news and views Road rage and fruit flies
Anne F Simon & David E Krantz Nature Genetics39, 581–582
(May 2007); doi:10.1038/ng0507-581
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letter Genetic reconstruction of a functional transcriptional regulatory network
Zhanzhi Hu, Patrick J Killion & Vishwanath R Iyer Nature Genetics39, 683–687
(May 2007); doi:10.1038/ng2012
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brief communication Duplication of the MYB oncogene in T cell acute lymphoblastic leukemia
Idoya Lahortiga, Kim De Keersmaecker, Pieter Van Vlierberghe, Carlos Graux, Barbara Cauwelier, Frederic Lambert, Nicole Mentens, H Berna Beverloo, Rob Pieters, Frank Speleman, Maria D Odero, Marijke Bauters, Guy Froyen, Peter Marynen, Peter Vandenberghe, Iwona Wlodarska, Jules P P Meijerink & Jan Cools Nature Genetics39, 593–595
(May 2007); doi:10.1038/ng2025
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review Genetic determinants of cancer metastasis
Don X. Nguyen & Joan Massagué Nature Reviews Genetics8, 341–352
(May 2007); doi:10.1038/nrg2101
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article Serotonin modulates the response of embryonic thalamocortical axons to netrin-1
Alexandre Bonnin, Masaaki Torii, Lilly Wang, Pasko Rakic & Pat Levitt Nature Neuroscience10, 588–597
(May 2007); doi:10.1038/nn1896
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news and views Serotonin guides the way
Noah Gray Nature Neuroscience10, 542
(May 2007); doi:10.1038/nn0507-542
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review Cell cycle regulation in the postmitotic neuron: oxymoron or new biology?
Karl Herrup & Yan Yang Nature Reviews Neuroscience8, 368–378
(May 2007); doi:10.1038/nrn2124
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article A high-quality catalog of the Drosophila melanogaster proteome
Erich Brunner, Christian H Ahrens, Sonali Mohanty, Hansruedi Baetschmann, Sandra Loevenich, Frank Potthast, Eric W Deutsch, Christian Panse, Ulrik de Lichtenberg, Oliver Rinner, Hookeun Lee, Patrick G A Pedrioli, Johan Malmstrom, Katja Koehler, Sabine Schrimpf, Jeroen Krijgsveld, Floyd Kregenow, Albert J R Heck, Ernst Hafen, Ralph Schlapbach & Ruedi Aebersold Nature Biotechnology25, 576–583
(May 2007); doi:10.1038/nbt1300
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brief communication Quantitative proteomic assessment of very early cellular signaling events
Joern Dengjel, Vyacheslav Akimov, Jesper V Olsen, Jakob Bunkenborg, Matthias Mann, Blagoy Blagoev & Jens S Andersen Nature Biotechnology25, 566–568
(May 2007); doi:10.1038/nbt1301
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perspective Towards zoomable multidimensional maps of the cell
Zhenjun Hu, Joe Mellor, Jie Wu, Minoru Kanehisa, Joshua M Stuart & Charles DeLisi Nature Biotechnology25, 547–554
(May 2007); doi:10.1038/nbt1304
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review More than one reason to rethink the use of peptides in vaccine design
Anthony W. Purcell, James McCluskey & Jamie Rossjohn Nature Reviews Drug Discovery6, 404–414
(May 2007); doi:10.1038/nrd2224
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article H-NS cooperative binding to high-affinity sites in a regulatory element results in transcriptional silencing
Emeline Bouffartigues, Malcolm Buckle, Cyril Badaut, Andrew Travers & Sylvie Rimsky Nature Structural & Cell Biology14, 441–448
(May 2007); doi:10.1038/nsmb1233
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article Structural basis of Na+/K+-ATPase adaptation to marine environments
Claudia Colina, Joshua J C Rosenthal, Joseph A DeGiorgis, Deepa Srikumar, Nikhila Iruku & Miguel Holmgren Nature Structural & Cell Biology14, 427–431
(May 2007); doi:10.1038/nsmb1237
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news and views Budding insights on cell polarity
Dirk Fasshauer & Reinhard Jahn Nature Structural & Cell Biology14, 360–362
(May 2007); doi:10.1038/nsmb0507-360
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progress Manipulation of host Kruppel-like factor (KLF) function by exotoxins from diverse bacterial pathogens
Eoin O'Grady, Heidi Mulcahy, Claire Adams, John P. Morrissey & Fergal O'Gara Nature Reviews Microbiology5, 337–341
(May 2007); doi:10.1038/nrmicro1641
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article Chemoselective probes for metabolite enrichment and profiling
Erin E Carlson & Benjamin F Cravatt Nature Methods4, 429–435
(May 2007); doi:10.1038/nmeth1038
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news and views High-throughput screening flows along
Hicham Fenniri & Ramon Alvarez-Puebla Nature Chemical Biology3, 247–249
(May 2007); doi:10.1038/nchembio0507-247
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scientific report The Drosophila mitotic inhibitor Frühstart specifically binds to the hydrophobic patch of cyclins
Pawel Gawlinski, Rainer Nikolay, Catherine Goursot, Steffen Lawo, Bhagirath Chaurasia, Hans-Martin Herz, Yvonne Kusßler-Schneider, Thomas Ruppert, Matthias Mayer & Jörg Grosßhans EMBO Reports8, 490–496
(May 2007); doi:10.1038/sj.embor.7400948
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scientific report Cyclic AMP signalling in Dictyostelium: G-proteins activate separate Ras pathways using specific RasGEFs
Helmut Kae, Arjan Kortholt, Holger Rehmann, Robert H Insall, Peter J M Van Haastert, George B Spiegelman & Gerald Weeks EMBO Reports8, 477–482
(May 2007); doi:10.1038/sj.embor.7400936
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letter Wnt-dependent de novo hair follicle regeneration in adult mouse skin after wounding
Mayumi Ito, Zaixin Yang, Thomas Andl, Chunhua Cui, Noori Kim, Sarah E. Millar & George Cotsarelis Nature447, 316–320
(17 May 2007); doi:10.1038/nature05766
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letter SUMOylation regulates kainate-receptor-mediated synaptic transmission
Stéphane Martin, Atsushi Nishimune, Jack R. Mellor & Jeremy M. Henley Nature447, 321–325
(17 May 2007); doi:10.1038/nature05736
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news and views Regenerative biology: New hair from healing wounds
Cheng-Ming Chuong Nature447, 265–266
(17 May 2007); doi:10.1038/447265a
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news and views Neuroscience: Wrestling with SUMO
Françoise Coussen & Daniel Choquet Nature447, 271–272
(17 May 2007); doi:10.1038/nature05888
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letter Alp7/TACC is a crucial target in Ran–GTPase-dependent spindle formation in fission yeast
Masamitsu Sato & Takashi Toda Nature447, 334–337
(17 May 2007); doi:10.1038/nature05773
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review The emerging shape of the ESCRT machinery
Roger L. Williams & Sylvie Urbé Nature Reviews Molecular Cell Biology8, 355–368
(May 2007); doi:10.1038/nrm2162
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review The spindle-assembly checkpoint in space and time
Andrea Musacchio & Edward D. Salmon Nature Reviews Molecular Cell Biology8, 379–393
(May 2007); doi:10.1038/nrm2163
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letter Voltage-dependent anion channels are dispensable for mitochondrial-dependent cell death
Christopher P. Baines, Robert A. Kaiser, Tatiana Sheiko, William J. Craigen & Jeffery D. Molkentin Nature Cell Biology9, 550–555
(May 2007); doi:10.1038/ncb1575
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news and views Mitochondrial apoptosis without VDAC
Lorenzo Galluzzi & Guido Kroemer Nature Cell Biology9, 487–489
(May 2007); doi:10.1038/ncb0507-487
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letter Priming, initiation and synchronization of the segmentation clock by deltaD and deltaC
Andrew Mara, Joshua Schroeder, Cécile Chalouni & Scott A. Holley Nature Cell Biology9, 523–530
(May 2007); doi:10.1038/ncb1578
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review Foxp3 in control of the regulatory T cell lineage
Ye Zheng & Alexander Y Rudensky Nature Immunology8, 457–462
(May 2007); doi:10.1038/ni1455
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review Pax5: the guardian of B cell identity and function
César Cobaleda, Alexandra Schebesta, Alessio Delogu & Meinrad Busslinger Nature Immunology8, 463–470
(May 2007); doi:10.1038/ni1454
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essay Trawling for treasure: tales of T-bet
Laurie H Glimcher Nature Immunology8, 448–450
(May 2007); doi:10.1038/ni0507-448
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review The family of five: TIR-domain-containing adaptors in Toll-like receptor signalling
Luke A. J. O'Neill & Andrew G. Bowie Nature Reviews Immunology7, 353–364
(May 2007); doi:10.1038/nri2079
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news and views Autism: highly heritable but not inherited
Arthur L Beaudet Nature Medicine13, 534–536
(May 2007); doi:10.1038/nm0507-534
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review TLR-dependent and TLR-independent pathways of type I interferon induction in systemic autoimmunity
Roberto Baccala, Kasper Hoebe, Dwight H Kono, Bruce Beutler & Argyrios N Theofilopoulos Nature Medicine13, 543–551
(May 2007); doi:10.1038/nm1590
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review Therapeutic targeting of innate immunity with Toll-like receptor agonists and antagonists
Holger Kanzler, Franck J Barrat, Edith M Hessel & Robert L Coffman Nature Medicine13, 552–559
(May 2007); doi:10.1038/nm1589
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review Second generation inhibitors of BCR–ABL for the treatment of imatinib-resistant chronic myeloid leukaemia
Ellen Weisberg, Paul W. Manley, Sandra W. Cowan-Jacob, Andreas Hochhaus & James D. Griffin Nature Reviews Cancer7, 345–356
(May 2007); doi:10.1038/nrc2126
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perspective Insights from transgenic mouse models of ERBB2-induced breast cancer
Josie Ursini-Siegel, Babette Schade, Robert D. Cardiff & William J. Muller Nature Reviews Cancer7, 389–397
(May 2007); doi:10.1038/nrc2127
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letter Estrogen receptor alpha (ESR1) gene amplification is frequent in breast cancer
Frederik Holst, Phillip R Stahl, Christian Ruiz, Olaf Hellwinkel, Zeenath Jehan, Marc Wendland, Annette Lebeau, Luigi Terracciano, Khawla Al-Kuraya, Fritz Jänicke, Guido Sauter & Ronald Simon Nature Genetics39, 655–660
(May 2007); doi:10.1038/ng2006
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letter Homozygous mutation of AURKC yields large-headed polyploid spermatozoa and causes male infertility
Klaus Dieterich, Ricardo Soto Rifo, Anne Karen Faure, Sylviane Hennebicq, Baha Ben Amar, Mohamed Zahi, Julia Perrin, Delphine Martinez, Bernard Sèle, Pierre-Simon Jouk, Théophile Ohlmann, Sophie Rousseaux, Joel Lunardi & Pierre F Ray Nature Genetics39, 661–665
(May 2007); doi:10.1038/ng2027
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letter Impaired microRNA processing enhances cellular transformation and tumorigenesis
Madhu S Kumar, Jun Lu, Kim L Mercer, Todd R Golub & Tyler Jacks Nature Genetics39, 673–677
(May 2007); doi:10.1038/ng2003
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news and views MicroRNAs as tumor suppressors
Scott M Hammond Nature Genetics39, 582–583
(May 2007); doi:10.1038/ng0507-582
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review Biology by numbers: mathematical modelling in developmental biology
Claire J. Tomlin & Jeffrey D. Axelrod Nature Reviews Genetics8, 331–340
(May 2007); doi:10.1038/nrg2098
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article Caenorhabditis elegans TRPA-1 functions in mechanosensation
Katie S Kindt, Veena Viswanath, Lindsey Macpherson, Kathleen Quast, Hongzhen Hu, Ardem Patapoutian & William R Schafer Nature Neuroscience10, 568–577
(May 2007); doi:10.1038/nn1886
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brief communication CLOCK and NPAS2 have overlapping roles in the suprachiasmatic circadian clock
Jason P DeBruyne, David R Weaver & Steven M Reppert Nature Neuroscience10, 543–545
(May 2007); doi:10.1038/nn1884
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review Epigenetic regulation in psychiatric disorders
Nadia Tsankova, William Renthal, Arvind Kumar & Eric J. Nestler Nature Reviews Neuroscience8, 355–545
(May 2007); doi:10.1038/nrn2132
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article High-throughput identification of transcription start sites, conserved promoter motifs and predicted regulons
Patrick T McGrath, Honglak Lee, Li Zhang, Antonio A Iniesta, Alison K Hottes, Meng How Tan, Nathan J Hillson, Ping Hu, Lucy Shapiro & Harley H McAdams Nature Biotechnology25, 584–592
(May 2007); doi:10.1038/nbt1294
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review The vanilloid receptor TRPV1: 10 years from channel cloning to antagonist proof-of-concept
Arpad Szallasi, Daniel N. Cortright, Charles A. Blum & Samer R. Eid Nature Reviews Drug Discovery6, 357–372
(May 2007); doi:10.1038/nrd2280
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perspective Development trends for monoclonal antibody cancer therapeutics
Janice M. Reichert & Viia E. Valge-Archer Nature Reviews Drug Discovery6, 349–356
(May 2007); doi:10.1038/nrd2241
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article Structural basis for Rab GTPase activation by VPS9 domain exchange factors
Anna Delprato & David G Lambright Nature Structural & Molecular Biology14, 406–412
(May 2007); doi:10.1038/nsmb1232
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brief communication Structure-based design of a pathway-specific nuclear import inhibitor
Ahmet E Cansizoglu, Brittany J Lee, Zi Chao Zhang, Beatriz M A Fontoura & Yuh Min Chook Nature Structural & Molecular Biology14, 452–454
(May 2007); doi:10.1038/nsmb1229
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article Image-based multivariate profiling of drug responses from single cells
Lit-Hsin Loo, Lani F Wu & Steven J Altschuler Nature Methods4, 445–453
(May 2007); doi:10.1038/nmeth1032
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brief communication Ligand interaction scan: a general method for engineering ligand-sensitive protein alleles
Oran Erster, Miriam Eisenstein & Mordechai Liscovitch Nature Methods4, 393–395
(May 2007); doi:10.1038/nmeth1046
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letter Molecular imaging of hydrogen peroxide produced for cell signaling
Evan W Miller, Orapim Tulyathan, Ehud Y Isacoff & Christopher J Chang Nature Chemical Biology3, 263–267
(May 2007); doi:10.1038/nchembio871
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news and views Measuring H2O2 produced in response to cell surface receptor activation
Sue Goo Rhee Nature Chemical Biology3, 244–246
(May 2007); doi:10.1038/nchembio0507-244
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scientific report Retroviral oncoprotein Tax deregulates NF-κB by activating Tak1 and mediating the physical association of Tak1–IKK
Xuefeng Wu & Shao-Cong Sun EMBO Reports8, 510–515
(May 2007); doi:10.1038/sj.embor.7400931
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scientific report Telomere dysfunction suppresses spontaneous tumorigenesis in vivo by initiating p53-dependent cellular senescence
Wilfredo Cosme-Blanco, Mei-Feng Shen, Alexander J F Lazar, Sen Pathak, Guillermina Lozano, Asha S Multani & Sandy Chang EMBO Reports8, 497–503
(May 2007); doi:10.1038/sj.embor.7400937
| Summary | Full Text (HTML / PDF) |
article Genome of the marsupial Monodelphis domestica reveals innovation in non-coding sequences
Tarjei S. Mikkelsen et al. Nature447, 167–177
(10 May 2007); doi:10.1038/nature05805
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letter A chromatin link that couples cell division to root epidermis patterning in Arabidopsis
Elena Caro, M. Mar Castellano & Crisanto Gutierrez Nature447, 213–217
(10 May 2007); doi:10.1038/nature05763
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letter The carboxy terminus of NBS1 is required for induction of apoptosis by the MRE11 complex
Travis H. Stracker, Monica Morales, Suzana S. Couto, Hussein Hussein & John H. J. Petrini Nature447, 218–221
(10 May 2007); doi:10.1038/nature05740
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letter The human RNA kinase hClp1 is active on 3' transfer RNA exons and short interfering RNAs
Stefan Weitzer & Javier Martinez Nature447, 222–226
(10 May 2007); doi:10.1038/nature05777
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news and views Behavioural neuroscience: Down memory lane
J. David Sweatt Nature447, 151–152
(10 May 2007); doi:10.1038/nature05716
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letter C. elegans mitochondrial factor WAH-1 promotes phosphatidylserine externalization in apoptotic cells through phospholipid scramblase SCRM-1
Xiaochen Wang, Jin Wang, Keiko Gengyo-Ando, Lichuan Gu, Chun-Ling Sun, Chonglin Yang, Yong Shi, Tetsuo Kobayashi, Yigong Shi, Shohei Mitani, Xiao-Song Xie & Ding Xue Nature Cell Biology9, 541–549
(May 2007); doi:10.1038/ncb1574
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letter pVHL and GSK3β are components of a primary cilium-maintenance signalling network
Claudio R. Thoma, Ian J. Frew, Christian R. Hoerner, Matteo Montani, Holger Moch & Wilhelm Krek Nature Cell Biology9, 588–595
(May 2007); doi:10.1038/ncb1579
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letter Loss of Drosophila Myb interrupts the progression of chromosome condensation
J. Robert Manak, Hong Wen, Tran Van, Laura Andrejka & Joseph S. Lipsick Nature Cell Biology9, 581–587
(May 2007); doi:10.1038/ncb1580
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review Stem-cell niches: nursery rhymes across kingdoms
Ben Scheres Nature Reviews Molecular Cell Biology8, 345–354
(May 2007); doi:10.1038/nrm2164
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article Production of Ins(1,3,4,5)P4 mediated by the kinase Itpkb inhibits store-operated calcium channels and regulates B cell selection and activation
Andrew T Miller, Mark Sandberg, Yina H Huang, Michael Young, Susan Sutton, Karsten Sauer & Michael P Cooke Nature Immunology8, 514–521
(May 2007); doi:10.1038/ni1458
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review Regulation of lymphocyte development by Notch signaling
Kenji Tanigaki & Tasuku Honjo Nature Immunology8, 451–456
(May 2007); doi:10.1038/ni1453
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essay Blimp-1 over Budapest
Mark M Davis Nature Immunology8, 445–447
(May 2007); doi:10.1038/ni0507-445
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article MIF is a noncognate ligand of CXC chemokine receptors in inflammatory and atherogenic cell recruitment
Jürgen Bernhagen, Regina Krohn, Hongqi Lue, Julia L Gregory, Alma Zernecke, Rory R Koenen, Manfred Dewor, Ivan Georgiev, Andreas Schober, Lin Leng, Teake Kooistra, Günter Fingerle-Rowson, Pietro Ghezzi, Robert Kleemann, Shaun R McColl, Richard Bucala, Michael J Hickey & Christian Weber Nature Medicine13, 587–596
(May 2007); doi:10.1038/nm1567
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letter Cyclic AMP-regulated exocytosis of Escherichia coli from infected bladder epithelial cells
Brian L Bishop, Mathew J Duncan, Jeongmin Song, Guojie Li, David Zaas & Soman N Abraham Nature Medicine13, 625–630
(May 2007); doi:10.1038/nm1572
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news and views Flushing bacteria out of the bladder
Danelle S Eto & Matthew A Mulvey Nature Medicine13, 531–532
(May 2007); doi:10.1038/nm0507-531
| Summary | Full Text (HTML / PDF) |
news and views A new way to regulate the NMJ
Kay E Davies & Tejvir S Khurana Nature Medicine13, 538–539
(May 2007); doi:10.1038/nm0507-538
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review PIN1, the cell cycle and cancer
Elizabeth S. Yeh & Anthony R. Means Nature Reviews Cancer7, 381–388
(May 2007); doi:10.1038/nrc2107
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letter Genome-wide association study identifies a second prostate cancer susceptibility variant at 8q24
Julius Gudmundsson, Patrick Sulem, Andrei Manolescu, Laufey T Amundadottir, Daniel Gudbjartsson, Agnar Helgason, Thorunn Rafnar, Jon T Bergthorsson, Bjarni A Agnarsson, Adam Baker, Asgeir Sigurdsson, Kristrun R Benediktsdottir, Margret Jakobsdottir, Jianfeng Xu, Thorarinn Blondal, Jelena Kostic, Jielin Sun, Shyamali Ghosh, Simon N Stacey, Magali Mouy, Jona Saemundsdottir, Valgerdur M Backman, Kristleifur Kristjansson, Alejandro Tres, Alan W Partin, Marjo T Albers-Akkers, Javier Godino-Ivan Marcos, Patrick C Walsh, Dorine W Swinkels, Sebastian Navarrete, Sarah D Isaacs, Katja K Aben, Theresa Graif, John Cashy, Manuel Ruiz-Echarri, Kathleen E Wiley, Brian K Suarez, J Alfred Witjes, Mike Frigge, Carole Ober, Eirikur Jonsson, Gudmundur V Einarsson, Jose I Mayordomo, Lambertus A Kiemeney, William B Isaacs, William J Catalona, Rosa B Barkardottir, Jeffrey R Gulcher, Unnur Thorsteinsdottir, Augustine Kong & Kari Stefansson Nature Genetics39, 631–637
(May 2007); doi:10.1038/ng1999
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letter Multiple regions within 8q24 independently affect risk for prostate cancer
Christopher A Haiman, Nick Patterson, Matthew L Freedman, Simon R Myers, Malcolm C Pike, Alicja Waliszewska, Julie Neubauer, Arti Tandon, Christine Schirmer, Gavin J McDonald, Steven C Greenway, Daniel O Stram, Loic Le Marchand, Laurence N Kolonel, Melissa Frasco, David Wong, Loreall C Pooler, Kristin Ardlie, Ingrid Oakley-Girvan, Alice S Whittemore, Kathleen A Cooney, Esther M John, Sue A Ingles, David Altshuler, Brian E Henderson & David Reich Nature Genetics39, 638–644
(May 2007); doi:10.1038/ng2015
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letter Genome-wide association study of prostate cancer identifies a second risk locus at 8q24
Meredith Yeager, Nick Orr, Richard B Hayes, Kevin B Jacobs, Peter Kraft, Sholom Wacholder, Mark J Minichiello, Paul Fearnhead, Kai Yu, Nilanjan Chatterjee, Zhaoming Wang, Robert Welch, Brian J Staats, Eugenia E Calle, Heather Spencer Feigelson, Michael J Thun, Carmen Rodriguez, Demetrius Albanes, Jarmo Virtamo, Stephanie Weinstein, Fredrick R Schumacher, Edward Giovannucci, Walter C Willett, Geraldine Cancel-Tassin, Olivier Cussenot, Antoine Valeri, Gerald L Andriole, Edward P Gelmann, Margaret Tucker, Daniela S Gerhard, Joseph F Fraumeni, Jr, Robert Hoover, David J Hunter, Stephen J Chanock & Gilles Thomas Nature Genetics39, 645–649
(May 2007); doi:10.1038/ng2022
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news and views Multiple prostate cancer risk variants on 8q24
John S Witte Nature Genetics39, 577
(May 2007); doi:10.1038/ng0507-579
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article A new function for the fragile X mental retardation protein in regulation of PSD-95 mRNA stability
Francesca Zalfa, Boris Eleuteri, Kirsten S Dickson, Valentina Mercaldo, Silvia De Rubeis, Alessandra di Penta, Elisabetta Tabolacci, Pietro Chiurazzi, Giovanni Neri, Seth G N Grant & Claudia Bagni Nature Neuroscience10, 578–587
(May 2007); doi:10.1038/nn1893
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perspective A risk-based bioanalytical strategy for the assessment of antibody immune responses against biological drugs
Gopi Shankar, Charles Pendley & Kathryn E Stein Nature Biotechnology25, 555–561
(May 2007); doi:10.1038/nbt1303
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review Targeting dual-specificity phosphatases: manipulating MAP kinase signalling and immune responses
Kate L. Jeffrey, Montserrat Camps, Christian Rommel & Charles R. Mackay Nature Reviews Drug Discovery6, 391–403
(May 2007); doi:10.1038/nrd2289
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article The uncoupled chloride conductance of a bacterial glutamate transporter homolog
Renae M Ryan & Joseph A Mindell Nature Structural & Molecular Biology14, 365–371
(May 2007); doi:10.1038/nsmb1230
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news and views A leak in the EAATs
Christopher Miller Nature Structural & Molecular Biology14, 356–357
(May 2007); doi:10.1038/nsmb0507-356
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brief communication A yeast two-hybrid smart-pool-array system for protein-interaction mapping
Fulai Jin, Larisa Avramova, Jing Huang & Tony Hazbun Nature Methods4, 405–407
(May 2007); doi:10.1038/nmeth1042
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letter Chemical genetics reveals a complex functional ground state of neural stem cells
Phedias Diamandis, Jan Wildenhain, Ian D Clarke, Adrian G Sacher, Jeremy Graham, David S Bellows, Erick K M Ling, Ryan J Ward, Leanne G Jamieson, Mike Tyers and Peter B Dirks Nature Chemical Biology3, 268–273
(May 2007); doi:10.1038/nchembio873
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news and views Chemical probes of neural stem cell self-renewal
Mark Mercola Nature Chemical Biology3, 246–247
(May 2007); doi:10.1038/nchembio0507-246
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letter Chitin induces accumulation in tissue of innate immune cells associated with allergy
Tiffany A. Reese, Hong-Erh Liang, Andrew M. Tager, Andrew D. Luster, Nico Van Rooijen, David Voehringer & Richard M. Locksley Nature447, 92–96
(03 May 2007); doi:10.1038/nature05746
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letter A positive feedback mechanism governs the polarity and motion of motile cilia
Brian Mitchell, Richard Jacobs, Julie Li, Shu Chien & Chris Kintner Nature447, 97–101
(03 May 2007); doi:10.1038/nature05771
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article Dose-dependent oncogene-induced senescence in vivo and its evasion during mammary tumorigenesis
Christopher J. Sarkisian, Blaine A. Keister, Douglas B. Stairs, Robert B. Boxer, Susan E. Moody & Lewis A. Chodosh Nature Cell Biology9, 493–505
(May 2007); doi:10.1038/ncb1567
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letter Flies without a spindle checkpoint
Eulalie Buffin, Doruk Emre & Roger E. Karess Nature Cell Biology9, 565–572
(May 2007); doi:10.1038/ncb1570
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letter A functional genomic screen identifies a role for TAO1 kinase in spindle-checkpoint signalling
Viji M. Draviam, Frank Stegmeier, Grzegorz Nalepa, Mathew E. Sowa, Jing Chen, Anthony Liang, Gregory J. Hannon, Peter K. Sorger, J. Wade Harper & Stephen J. Elledge Nature Cell Biology9, 556–564
(May 2007); doi:10.1038/ncb1569
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review The apoptosome: signalling platform of cell death
Stefan J. Riedl & Guy S. Salvesen Nature Reviews Molecular Cell Biology8, 405–413
(May 2007); doi:10.1038/nrm2153
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perspective Highway to the inner nuclear membrane: rules for the road
C. Patrick Lusk, Günter Blobel & Megan C. King Nature Reviews Molecular Cell Biology8, 414–420
(May 2007); doi:10.1038/nrm2165
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article Toll-like receptor 9-dependent activation by DNA-containing immune complexes is mediated by HMGB1 and RAGE
Jane Tian, Ana Maria Avalos, Su-Yau Mao, Bo Chen, Kannaki Senthil, Herren Wu, Peggy Parroche, Stacey Drabic, Douglas Golenbock, Cherilyn Sirois, Jing Hua, Ling Ling An, Laurent Audoly, Greg La Rosa, Angelika Bierhaus, Peter Naworth, Ann Marshak-Rothstein, Mary K Crow, Katherine A Fitzgerald, Eicke Latz, Peter A Kiener & Anthony J Coyle Nature Immunology8, 487–496
(May 2007); doi:10.1038/ni1457
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news and views TLR9 and DNA 'feel' RAGE
Arthur M Krieg Nature Immunology8, 475–477
(May 2007); doi:10.1038/ni0507-475
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review New developments in FcεRI regulation, function and inhibition
Stefan Kraft & Jean-Pierre Kinet Nature Reviews Immunology7, 365–378
(May 2007); doi:10.1038/nri2072
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review Molecular mechanisms of cardiotoxicity of tyrosine kinase inhibition
Thomas Force, Daniela S. Krause & Richard A. Van Etten Nature Reviews Cancer7, 332–344
(May 2007); doi:10.1038/nrc2106
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review Gene function in mouse embryogenesis: get set for gastrulation
Patrick P. L. Tam & David A. F. Loebel Nature Reviews Genetics8, 368–381
(May 2007); doi:10.1038/nrg2084
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article TRPC channels promote cerebellar granule neuron survival
Yichang Jia, Jian Zhou, Yilin Tai & Yizheng Wang Nature Neuroscience10, 559–567
(May 2007); doi:10.1038/nn1870
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news and views Something old, something new: BDNF-induced neuron survival requires TRPC channel function
Wayne S Sossin & Philip A Barker Nature Neuroscience10, 537–538
(May 2007); doi:10.1038/nn0507-537
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review Transcriptional regulation of vertebrate axon guidance and synapse formation
Franck Polleux, Gulayse Ince-Dunn & Anirvan Ghosh Nature Reviews Neuroscience8, 331–340
(May 2007); doi:10.1038/nrn2118
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article Imaging dynamics of endogenous mitochondrial RNA in single living cells
Takeaki Ozawa, Yutaka Natori, Moritoshi Sato & Yoshio Umezawa Nature Methods4, 413–419
(May 2007); doi:10.1038/nmeth1030
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article RNA visualization in live bacterial cells using fluorescent protein complementation
Maria Valencia-Burton, Ron M McCullough, Charles R Cantor & Natalia E Broude Nature Methods4, 421–427
(May 2007); doi:10.1038/nmeth1023
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brief communication A genomic integration method to visualize localization of endogenous mRNAs in living yeast
Liora Haim, Gadi Zipor, Stella Aronov & Jeffrey E Gerst Nature Methods4, 409–412
(May 2007); doi:10.1038/nmeth1040
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news and views Splitting or stacking fluorescent proteins to visualize mRNA in living cells
Sanjay Tyagi Nature Methods4, 391–392
(May 2007); doi:10.1038/nmeth0507-391
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