The Research Library categorizes, and provides access to, all recent signaling-related research published in the Nature Publishing Group journals. The selection is deliberately broad to facilitate access to all research impacting on the signaling community. Both primary research and review articles are included, as are 'News and Views' articles.
Click here for free access to the 'Featured Articles' section, with new articles every week.
article A lipid-based model for the creation of an escape hatch from the endoplasmic reticulum
Hidde L. Ploegh Nature448, 435–438
(26 July 2007); doi:10.1038/nature06004
| Summary | Full Text (HTML / PDF) |
article A transforming mutation in the pleckstrin homology domain of AKT1 in cancer
John D. Carpten, Andrew L. Faber, Candice Horn, Gregory P. Donoho, Stephen L. Briggs, Christiane M. Robbins, Galen Hostetter, Sophie Boguslawski, Tracy Y. Moses, Stephanie Savage, Mark Uhlik, Aimin Lin, Jian Du, Yue-Wei Qian, Douglas J. Zeckner, Greg Tucker-Kellogg, Jeffrey Touchman, Ketan Patel, Spyro Mousses, Michael Bittner, Richard Schevitz, Mei-Huei T. Lai, Kerry L. Blanchard & James E. Thomas Nature448, 439–444
(26 July 2007); doi:10.1038/nature05933
| Summary | Full Text (HTML / PDF) |
article Non-transcriptional control of DNA replication by c-Myc
David Dominguez-Sola, Carol Y. Ying, Carla Grandori, Luca Ruggiero, Brenden Chen, Muyang Li, Denise A. Galloway, Wei Gu, Jean Gautier & Riccardo Dalla-Favera Nature448, 445–451
(26 July 2007); doi:10.1038/nature05953
| Summary | Full Text (HTML / PDF) |
letter Protective and therapeutic role for αB-crystallin in autoimmune demyelination
Shalina S. Ousman, Beren H. Tomooka, Johannes M. van Noort, Eric F. Wawrousek, Kevin O'Conner, David A. Hafler, Raymond A. Sobel, William H. Robinson & Lawrence Steinman Nature448, 474–479
(26 July 2007); doi:10.1038/nature05935
| Summary | Full Text (HTML / PDF) |
news and views Inflammatory disease: Assault on the guardian
Richard M. Ransohoff Nature448, 421–422
(26 July 2007); doi:10.1038/448421a
| Full Text (HTML / PDF) |
letter Essential autocrine regulation by IL-21 in the generation of inflammatory T cells
Roza Nurieva, Xuexian O. Yang, Gustavo Martinez, Yongliang Zhang, Athanasia D. Panopoulos, Li Ma, Kimberly Schluns, Qiang Tian, Stephanie S. Watowich, Anton M. Jetten & Chen Dong Nature448, 480–483
(26 July 2007); doi:10.1038/nature05969
| Summary | Full Text (HTML / PDF) |
letter IL-21 initiates an alternative pathway to induce proinflammatory TH17 cells
Thomas Korn, Estelle Bettelli, Wenda Gao, Amit Awasthi, Anneli Jäger, Terry B. Strom, Mohamed Oukka & Vijay K. Kuchroo Nature448, 484–487
(26 July 2007); doi:10.1038/nature05970
| Summary | Full Text (HTML / PDF) |
news and views Immunology: Narcissistic helpers
Matthew T. Palmer & Casey T. Weaver Nature448, 416–418
(26 July 2007); doi:10.1038/448416a
| Full Text (HTML / PDF) |
letter Functional diversification of closely related ARF-GEFs in protein secretion and recycling
Sandra Richter, Niko Geldner, Jarmo Schrader, Hanno Wolters, York-Dieter Stierhof, Gabino Rios, Csaba Koncz, David G. Robinson & Gerd Jürgens Nature448, 488–492
(26 July 2007); doi:10.1038/nature05967
| Summary | Full Text (HTML / PDF) |
letter An ARF-GEF acting at the Golgi and in selective endocytosis in polarized plant cells
Ooi-kock Teh & Ian Moore Nature448, 493–496
(26 July 2007); doi:10.1038/nature06023
| Summary | Full Text (HTML / PDF) |
letter A flagellin-induced complex of the receptor FLS2 and BAK1 initiates plant defence
Delphine Chinchilla, Cyril Zipfel, Silke Robatzek, Birgit Kemmerling, Thorsten Nürnberger, Jonathan D. G. Jones, Georg Felix & Thomas Boller Nature448, 497–500
(26 July 2007); doi:10.1038/nature05999
| Summary | Full Text (HTML / PDF) |
letter DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response
Akinori Takaoka, ZhiChao Wang, Myoung Kwon Choi, Hideyuki Yanai, Hideo Negishi, Tatsuma Ban, Yan Lu, Makoto Miyagishi, Tatsuhiko Kodama, Kenya Honda, Yusuke Ohba & Tadatsugu Taniguchi Nature448, 501–505
(26 July 2007); doi:10.1038/nature06013
| Summary | Full Text (HTML / PDF) |
news and views Immunology: Sensing the enemy within
Hongbo Chi & Richard A. Flavell Nature448, 422–423
(26 July 2007); doi:10.1038/448423a
| Full Text (HTML / PDF) |
news and views Developmental biology: A ten per cent solution
John Reinitz Nature448, 420–421
(26 July 2007); doi:10.1038/448420a
| Full Text (HTML / PDF) |
review Unravelling the pathogenesis of inflammatory bowel disease
R. J. Xavier & D. K. Podolsky Nature448, 427–434
(26 July 2007); doi:10.1038/nature06005
| Summary | Full Text (HTML / PDF) |
article The ubiquitin-specific protease USP28 is required for MYC stability
Nikita Popov, Michael Wanzel, Mandy Madiredjo, Dong Zhang, Roderick Beijersbergen, Rene Bernards, Roland Moll, Stephen J. Elledge & Martin Eilers Nature Cell Biology9, 765–774
(July 2007); doi:10.1038/ncb1601
| Summary | Full Text (HTML / PDF) |
news and views MYC degradation: deubiquitinating enzymes enter the dance
Bruno Amati & Victor J. Sanchez-Arévalo Lobo Nature Cell Biology9, 729–731
(July 2007); doi:10.1038/ncb0707-729
| Summary | Full Text (HTML / PDF) |
article MicroRNAs 17-5p-20a-106a control monocytopoiesis through AML1 targeting and M-CSF receptor upregulation
Laura Fontana, Elvira Pelosi, Paolo Greco, Serena Racanicchi, Ugo Testa, Francesca Liuzzi, Carlo M. Croce, Ercole Brunetti, Francesco Grignani & Cesare Peschle Nature Cell Biology9, 775–787
(July 2007); doi:10.1038/ncb1613
| Summary | Full Text (HTML / PDF) |
letter Maximal chromosome compaction occurs by axial shortening in anaphase and depends on Aurora kinase
Felipe Mora-Bermúdez, Daniel Gerlich & Jan Ellenberg Nature Cell Biology9, 822–831
(July 2007); doi:10.1038/ncb1606
| Summary | Full Text (HTML / PDF) |
review Drosophila melanogaster embryonic haemocytes: masters of multitasking
Will Wood & Antonio Jacinto Nature Reviews Molecular Cell Biology8, 542–551
(July 2007); doi:10.1038/nrm2202
| Summary | Full Text (HTML / PDF) |
review Intermediate filaments: from cell architecture to nanomechanics
Harald Herrmann, Harald Bär, Laurent Kreplak, Sergei V. Strelkov & Ueli Aebi Nature Reviews Molecular Cell Biology8, 562–573
(July 2007); doi:10.1038/nrm2197
| Summary | Full Text (HTML / PDF) |
article Bcl-6 mediates the germinal center B cell phenotype and lymphomagenesis through transcriptional repression of the DNA-damage sensor ATR
Stella Maris Ranuncolo, Jose M Polo, Jamil Dierov, Michael Singer, Tracy Kuo, John Greally, Roland Green, Martin Carroll & Ari Melnick Nature Immunology8, 705–714
(July 2007); doi:10.1038/ni1478
| Summary | Full Text (HTML / PDF) |
article α1β1 integrin is crucial for accumulation of epidermal T cells and the development of psoriasis
Curdin Conrad, Onur Boyman, Giulia Tonel, Adrian Tun-Kyi, Ute Laggner, Antonin de Fougerolles, Victor Kotelianski, Humphrey Gardner & Frank O Nestle Nature Medicine13, 836–842
(July 2007); doi:10.1038/nm1605
| Summary | Full Text (HTML / PDF) |
news and views The problem with upward mobility
Johann E Gudjonsson & James T Elder Nature Medicine13, 786–787
(July 2007); doi:10.1038/nm0707-786
| Summary | Full Text (HTML / PDF) |
letter Identification of a key pathway required for the sterile inflammatory response triggered by dying cells
Chun-Jen Chen, Hajime Kono, Douglas Golenbock, George Reed, Shizuo Akira & Kenneth L Rock Nature Medicine13, 851–856
(July 2007); doi:10.1038/nm1603
| Summary | Full Text (HTML / PDF) |
news and views IL-1α responds to necrotic cell death
Keith B Elkon Nature Medicine13, 778–780
(July 2007); doi:10.1038/nm0707-778
| Summary | Full Text (HTML / PDF) |
review Gene methylation and early detection of genitourinary cancer: the road ahead
Paul Cairns Nature Reviews Cancer7, 531–543
(July 2007); doi:10.1038/nrc2170
| Summary | Full Text (HTML / PDF) |
perspective Targeting the protein kinase C family: are we there yet?
Helen J. Mackay & Christopher J. Twelves Nature Reviews Cancer7, 554–562
(July 2007); doi:10.1038/nrc2168
| Summary | Full Text (HTML / PDF) |
letter A genome-wide association study identifies alleles in FGFR2 associated with risk of sporadic postmenopausal breast cancer
David J Hunter, Peter Kraft, Kevin B Jacobs, David G Cox, Meredith Yeager, Susan E Hankinson, Sholom Wacholder, Zhaoming Wang, Robert Welch, Amy Hutchinson, Junwen Wang, Kai Yu, Nilanjan Chatterjee, Nick Orr, Walter C Willett, Graham A Colditz, Regina G Ziegler, Christine D Berg, Saundra S Buys, Catherine A McCarty, Heather Spencer Feigelson, Eugenia E Calle, Michael J Thun, Richard B Hayes, Margaret Tucker, Daniela S Gerhard, Joseph F Fraumeni, Jr, Robert N Hoover, Gilles Thomas & Stephen J Chanock Nature Genetics39, 870–874
(July 2007); doi:10.1038/ng2075
| Summary | Full Text (HTML / PDF) |
news and views ENCODE and our very busy genome
Steven Henikoff Nature Genetics39, 817–818
(July 2007); doi:10.1038/ng0707-817
| Summary | Full Text (HTML / PDF) |
brief communication A genome-wide association study for celiac disease identifies risk variants in the region harboring IL2 and IL21
David A van Heel, Lude Franke, Karen A Hunt, Rhian Gwilliam, Alexandra Zhernakova, Mike Inouye, Martin C Wapenaar, Martin C N M Barnardo, Graeme Bethel, Geoffrey K T Holmes, Con Feighery, Derek Jewell, Dermot Kelleher, Parveen Kumar, Simon Travis, Julian RF Walters, David S Sanders, Peter Howdle, Jill Swift, Raymond J Playford, William M McLaren, M Luisa Mearin, Chris J Mulder, Ross McManus, Ralph McGinnis, Lon R Cardon, Panos Deloukas & Cisca Wijmenga Nature Genetics39, 827–829
(July 2007); doi:10.1038/ng2058
| Summary | Full Text (HTML / PDF) |
perspective Planar cell polarity: one or two pathways?
Peter A. Lawrence, Gary Struhl & José Casal Nature Reviews Genetics8, 555–563
(July 2007); doi:10.1038/nrg2125
| Summary | Full Text (HTML / PDF) |
article A central role for Necl4 (SynCAM4) in Schwann cell–axon interaction and myelination
Ivo Spiegel, Konstantin Adamsky, Yael Eshed, Ron Milo, Helena Sabanay, Offra Sarig-Nadir, Ido Horresh, Steven S Scherer, Matthew N Rasband & Elior Peles Nature Neuroscience10, 861–869
(July 2007); doi:10.1038/nn1915
| Summary | Full Text (HTML / PDF) |
article Cannabinoids mediate analgesia largely via peripheral type 1 cannabinoid receptors in nociceptors
Nitin Agarwal, Pal Pacher, Irmgard Tegeder, Fumimasa Amaya, Cristina E Constantin, Gary J Brenner, Tiziana Rubino, Christoph W Michalski, Giovanni Marsicano, Krisztina Monory, Ken Mackie, Claudiu Marian, Sandor Batkai, Daniela Parolaro, Michael J Fischer, Peter Reeh, George Kunos, Michaela Kress, Beat Lutz, Clifford J Woolf & Rohini Kuner Nature Neuroscience10, 870–879
(July 2007); doi:10.1038/nn1916
| Summary | Full Text (HTML / PDF) |
review TRP channels in mechanosensation: direct or indirect activation?
Adam P. Christensen & David P. Corey Nature Reviews Neuroscience8, 510–521
(July 2007); doi:10.1038/nrn2149
| Summary | Full Text (HTML / PDF) |
review The contribution of immunology to the rational design of novel antibacterial vaccines
Stefan H.E. Kaufmann Nature Reviews Microbiology5, 491–504
(July 2007); doi:10.1038/nrmicro1688
| Summary | Full Text (HTML / PDF) |
review The perfect mix: recent progress in adjuvant research
Bruno Guy Nature Reviews Microbiology5, 505–517
(July 2007); doi:10.1038/nrmicro1681
| Summary | Full Text (HTML / PDF) |
article Calcium Green FlAsH as a genetically targeted small-molecule calcium indicator
Oded Tour, Stephen R Adams, Rex A Kerr, Rene M Meijer, Terrence J Sejnowski, Richard W Tsien & Roger Y Tsien Nature Chemical Biology3, 423–431
(July 2007); doi:10.1038/nchembio.2007.4
| Summary | Full Text (HTML / PDF) |
news and views Calcium channels light up
Eric Green & Ricardo E Dolmetsch Nature Chemical Biology3, 369–370
(July 2007); doi:10.1038/nchembio0707-369
| Full Text (HTML / PDF) |
article Generation of germline-competent induced pluripotent stem cells
Keisuke Okita, Tomoko Ichisaka & Shinya Yamanaka Nature448, 313–317
(19 July 2007); doi:10.1038/nature05934
| Summary | Full Text (HTML / PDF) |
article In vitro reprogramming of fibroblasts into a pluripotent ES-cell-like state
Marius Wernig, Alexander Meissner, Ruth Foreman, Tobias Brambrink, Manching Ku, Konrad Hochedlinger, Bradley E. Bernstein & Rudolf Jaenisch Nature448, 318–324
(19 July 2007); doi:10.1038/nature05944
| Summary | Full Text (HTML / PDF) |
article Rhythmic growth explained by coincidence between internal and external cues
Kazunari Nozue, Michael F. Covington, Paula D. Duek, Séverine Lorrain, Christian Fankhauser, Stacey L. Harmer & Julin N. Maloof Nature448, 358–361
(19 July 2007); doi:10.1038/nature05946
| Summary | Full Text (HTML / PDF) |
news and views Plant biology: Time for growth
Ghislain Breton & Steve A. Kay Nature448, 265–266
(19 July 2007); doi:10.1038/448265a
| Full Text (HTML / PDF) |
letter The Rab8 GTPase regulates apical protein localization in intestinal cells
Takashi Sato, Sotaro Mushiake, Yukio Kato, Ken Sato, Miyuki Sato, Naoki Takeda, Keiichi Ozono, Kazunori Miki, Yoshiyuki Kubo, Akira Tsuji, Reiko Harada & Akihiro Harada Nature448, 366–369
(19 July 2007); doi:10.1038/nature05929
| Summary | Full Text (HTML / PDF) |
news and views Cell biology: Caught in the traffic
Aparna Lakkaraju & Enrique Rodriguez-Boulan Nature448, 266–267
(19 July 2007); doi:10.1038/448266a
| Full Text (HTML / PDF) |
letter A bacterial E3 ubiquitin ligase targets a host protein kinase to disrupt plant immunity
Tracy R. Rosebrock, Lirong Zeng, Jennifer J. Brady, Robert B. Abramovitch, Fangming Xiao & Gregory B. Martin Nature448, 370–374
(19 July 2007); doi:10.1038/nature05966
| Summary | Full Text (HTML / PDF) |
letter Delayed ageing through damage protection by the Arf/p53 pathway
Ander Matheu, Antonio Maraver, Peter Klatt, Ignacio Flores, Isabel Garcia-Cao, Consuelo Borras, Juana M. Flores, Jose Viña, Maria A. Blasco & Manuel Serrano Nature448, 375–379
(19 July 2007); doi:10.1038/nature05949
| Summary | Full Text (HTML / PDF) |
article BACE1 regulates voltage-gated sodium channels and neuronal activity
Doo Yeon Kim, Bryce W. Carey, Haibin Wang, Laura A. M. Ingano, Alexander M. Binshtok, Mary H. Wertz, Warren H. Pettingell, Ping He, Virginia M.-Y. Lee, Clifford J. Woolf & Dora M. Kovacs Nature Cell Biology9, 755–764
(July 2007); doi:10.1038/ncb1602
| Summary | Full Text (HTML / PDF) |
letter Wnt signalling regulates paxillin ubiquitination essential for mesodermal cell motility
Hidekazu Iioka, Shun-ichiro Iemura, Tohru Natsume & Noriyuki Kinoshita Nature Cell Biology9, 813–821
(July 2007); doi:10.1038/ncb1607
| Summary | Full Text (HTML / PDF) |
letter NUP98–NSD1 links H3K36 methylation to Hox-A gene activation and leukaemogenesis
Gang G. Wang, Ling Cai, Martina P. Pasillas & Mark P. Kamps Nature Cell Biology9, 804–812
(July 2007); doi:10.1038/ncb1608
| Summary | Full Text (HTML / PDF) |
review Mechanisms of specificity in protein phosphorylation
Jeffrey A. Ubersax & James E. Ferrell Jr Nature Reviews Molecular Cell Biology8, 530–541
(July 2007); doi:10.1038/nrm2203
| Summary | Full Text (HTML / PDF) |
article IgEb immune complexes activate macrophages through FcγRIV binding
Masayuki Hirano, Randall S Davis, W David Fine, Shugo Nakamura, Kentaro Shimizu, Hirokazu Yagi, Koichi Kato, Robert P Stephan & Max D Cooper Nature Immunology8, 762–771
(July 2007); doi:10.1038/ni1477
| Summary | Full Text (HTML / PDF) |
review T cell development: better living through chromatin
Michael S Krangel Nature Immunology8, 687–694
(July 2007); doi:10.1038/ni1484
| Summary | Full Text (HTML / PDF) |
review How Ebola and Marburg viruses battle the immune system
Mansour Mohamadzadeh, Lieping Chen & Alan L. Schmaljohn Nature Reviews Immunology7, 556–694
(July 2007); doi:10.1038/nri2098
| Summary | Full Text (HTML / PDF) |
article Neuropeptide Y acts directly in the periphery on fat tissue and mediates stress-induced obesity and metabolic syndrome
Lydia E Kuo, Joanna B Kitlinska, Jason U Tilan, Lijun Li, Stephen B Baker, Michael D Johnson, Edward W Lee, Mary Susan Burnett, Stanley T Fricke, Richard Kvetnansky, Herbert Herzog & Zofia Zukowska Nature Medicine13, 803–811
(July 2007); doi:10.1038/nm1611
| Summary | Full Text (HTML / PDF) |
correspondence Stress, diet and abdominal obesity: Y?
James P Warne & Mary F Dallman Nature Medicine13, 781–783
(July 2007); doi:10.1038/nm0707-781
| Summary | Full Text (HTML / PDF) |
article Fen1 mutations result in autoimmunity, chronic inflammation and cancers
Li Zheng, Huifang Dai, Mian Zhou, Mei Li, Purnima Singh, Junzhuan Qiu, Walter Tsark, Qin Huang, Kemp Kernstine, Xuemei Zhang, Dongxin Lin & Binghui Shen Nature Medicine13, 812–819
(July 2007); doi:10.1038/nm1599
| Summary | Full Text (HTML / PDF) |
article Inhibition of CDK1 as a potential therapy for tumors over-expressing MYC
Andrei Goga, Dun Yang, Aaron D Tward, David O Morgan & J Michael Bishop Nature Medicine13, 820–827
(July 2007); doi:10.1038/nm1606
| Summary | Full Text (HTML / PDF) |
review Calcium and cancer: targeting Ca2+ transport
Gregory R. Monteith, Damara McAndrew, Helen M. Faddy & Sarah J. Roberts-Thomson Nature Reviews Cancer7, 519–530
(July 2007); doi:10.1038/nrc2171
| Summary | Full Text (HTML / PDF) |
perspective Taking gene-expression profiling to the clinic: when will molecular signatures become relevant to patient care?
Christos Sotiriou & Martine J. Piccart Nature Reviews Cancer7, 545–553
(July 2007); doi:10.1038/nrc2173
| Summary | Full Text (HTML / PDF) |
brief communication Deficiency of PORCN, a regulator of Wnt signaling, is associated with focal dermal hypoplasia
Karl-Heinz Grzeschik, Dorothea Bornholdt, Frank Oeffner, Arne König, María del Carmen Boente, Herbert Enders, Barbara Fritz, Michael Hertl, Ute Grasshoff, Katja Höfling, Vinzenz Oji, Mauro Paradisi, Christian Schuchardt, Zsuzsanna Szalai, Gianluca Tadini, Heiko Traupe & Rudolf Happle Nature Genetics39, 833–835
(July 2007); doi:10.1038/ng2052
| Summary | Full Text (HTML / PDF) |
brief communication Mutations in X-linked PORCN, a putative regulator of Wnt signaling, cause focal dermal hypoplasia
Xiaoling Wang, V Reid Sutton, J Omar Peraza-Llanes, Zhiyin Yu, Rebecca Rosetta, Ying-Chuck Kou, Tanya N Eble, Ankita Patel, Christina Thaller, Ping Fang & Ignatia B Van den Veyver Nature Genetics39, 836–838
(July 2007); doi:10.1038/ng2057
| Summary | Full Text (HTML / PDF) |
news and views Wnt signaling in focal dermal hypoplasia
Amy S Paller Nature Genetics39, 820–821
(July 2007); doi:10.1038/ng0707-820
| Summary | Full Text (HTML / PDF) |
review Chromatin crosstalk in development and disease: lessons from REST
Lezanne Ooi & Ian C. Wood Nature Reviews Genetics8, 544–554
(July 2007); doi:10.1038/nrg2100
| Summary | Full Text (HTML / PDF) |
article Cyclin-dependent kinase 5 governs learning and synaptic plasticity via control of NMDAR degradation
Ammar H Hawasli, David R Benavides, Chan Nguyen, Janice W Kansy, Kanehiro Hayashi, Pierre Chambon, Paul Greengard, Craig M Powell, Donald C Cooper & James A Bibb Nature Neuroscience10, 880–886
(July 2007); doi:10.1038/nn1914
| Summary | Full Text (HTML / PDF) |
news and views Bypassing interneurons: inhibition in neocortex
Barry W Connors & Scott J Cruikshank Nature Neuroscience10, 808–810
(July 2007); doi:10.1038/nn0707-808
| Summary | Full Text (HTML / PDF) |
article Regulation of T-type calcium channels by Rho-associated kinase
Mircea Iftinca, Jawed Hamid, Lina Chen, Diego Varela, Reza Tadayonnejad, Christophe Altier, Ray W Turner & Gerald W Zamponi Nature Neuroscience10, 854–860
(July 2007); doi:10.1038/nn1921
| Summary | Full Text (HTML / PDF) |
resources Characterization of human embryonic stem cell lines by the International Stem Cell Initiative
The International Stem Cell Initiative Nature Biotechnology25, 803–816
(July 2007); doi:10.1038/nbt1318
| Summary | Full Text (HTML / PDF) |
review Utilizing RNA interference to enhance cancer drug discovery
Elizabeth Iorns, Christopher J. Lord, Nicholas Turner & Alan Ashworth Nature Reviews Drug Discovery6, 556–568
(July 2007); doi:10.1038/nrd2355
| Summary | Full Text (HTML / PDF) |
article The SMC5/6 complex maintains telomere length in ALT cancer cells through SUMOylation of telomere-binding proteins
Patrick Ryan Potts & Hongtao Yu Nature Structural & Molecular Biology14, 581–590
(July 2007); doi:10.1038/nsmb1259
| Summary | Full Text (HTML / PDF) |
news and views A SUMO ligase for ALT
Roger R Reddel Nature Structural & Molecular Biology14, 570–571
(July 2007); doi:10.1038/nsmb0707-570
| Summary | Full Text (HTML / PDF) |
article The multifunctional RNA-binding protein hnRNP A1 is required for processing of miR-18a
Sonia Guil & Javier F Cáceres Nature Structural & Molecular Biology14, 591–596
(July 2007); doi:10.1038/nsmb1250
| Summary | Full Text (HTML / PDF) |
news and views Not miR-ly a splicing factor: hnRNP A1 succumbs to microRNA temptation
Anne Færch Nielsen, Philipp J F Leuschner & Javier Martinez Nature Structural & Molecular Biology14, 572–573
(July 2007); doi:10.1038/nsmb0707-572
| Summary | Full Text (HTML / PDF) |
article Determination of the sites of tyrosine O-sulfation in peptides and proteins
Yonghao Yu, Adam J Hoffhines, Kevin L Moore & Julie A Leary Nature Methods4, 583–588
(July 2007); doi:10.1038/nmeth1056
| Summary | Full Text (HTML / PDF) |
scientific report The N terminus of the serpin, tengpin, functions to trap the metastable native state
Qingwei Zhang, Ashley M Buckle, Ruby H P Law, Mary C Pearce, Lisa D Cabrita, Gordon J Lloyd, James A Irving, A Ian Smith, Katya Ruzyla, Jamie Rossjohn, Stephen P Bottomley & James C Whisstock EMBO Reports8, 658–663
(July 2007); doi:10.1038/sj.embor.7400986
| Summary | Full Text (HTML / PDF) |
article A genome-wide transgenic RNAi library for conditional gene inactivation in Drosophila
Georg Dietzl, Doris Chen, Frank Schnorrer, Kuan-Chung Su, Yulia Barinova, Michaela Fellner, Beate Gasser, Kaolin Kinsey, Silvia Oppel, Susanne Scheiblauer, Africa Couto, Vincent Marra, Krystyna Keleman & Barry J. Dickson Nature448, 151–156
(12 July 2007); doi:10.1038/nature05954
| Summary | Full Text (HTML / PDF) |
letter Derivation of pluripotent epiblast stem cells from mammalian embryos
I. Gabrielle M. Brons, Lucy E. Smithers, Matthew W. B. Trotter, Peter Rugg-Gunn, Bowen Sun, Susana M. Chuva de Sousa Lopes, Sarah K. Howlett, Amanda Clarkson, Lars Ahrlund-Richter, Roger A. Pedersen & Ludovic Vallier Nature448, 191–195
(12 July 2007); doi:10.1038/nature05950
| Summary | Full Text (HTML / PDF) |
letter New cell lines from mouse epiblast share defining features with human embryonic stem cells
Paul J. Tesar, Josh G. Chenoweth, Frances A. Brook, Timothy J. Davies, Edward P. Evans, David L. Mack, Richard L. Gardner & Ronald D. G. McKay Nature448, 196–199
(12 July 2007); doi:10.1038/nature05972
| Summary | Full Text (HTML / PDF) |
letter An intracellular P2X receptor required for osmoregulation in Dictyostelium discoideum
Samuel J. Fountain, Katie Parkinson, Mark T. Young, Lishuang Cao, Christopher R. L. Thompson & R. Alan North Nature448, 200–203
(12 July 2007); doi:10.1038/nature05926
| Summary | Full Text (HTML / PDF) |
letter The menthol receptor TRPM8 is the principal detector of environmental cold
Diana M. Bautista, Jan Siemens, Joshua M. Glazer, Pamela R. Tsuruda, Allan I. Basbaum, Cheryl L. Stucky, Sven-Eric Jordt & David Julius Nature448, 204–208
(12 July 2007); doi:10.1038/nature05910
| Summary | Full Text (HTML / PDF) |
letter An efflux transporter of silicon in rice
Jian Feng Ma, Naoki Yamaji, Namiki Mitani, Kazunori Tamai, Saeko Konishi, Toru Fujiwara, Maki Katsuhara & Masahiro Yano Nature448, 209–212
(12 July 2007); doi:10.1038/nature05964
| Summary | Full Text (HTML / PDF) |
article Dishevelled promotes axon differentiation by regulating atypical protein kinase C
Xian Zhang, Ji Zhu, Guo-Ying Yang, Qing-Jie Wang, Lei Qian, Yan-Min Chen, Fei Chen, Yu Tao, Han-Song Hu, Tong Wang & Zhen-Ge Luo Nature Cell Biology9, 743–754
(July 2007); doi:10.1038/ncb1603
| Summary | Full Text (HTML / PDF) |
news and views Extrinsic Wnt signalling controls the polarity component aPKC
Shigeo Ohno Nature Cell Biology9, 738–740
(July 2007); doi:10.1038/ncb0707-738
| Summary | Full Text (HTML / PDF) |
letter Molecular basis for the functional interaction of dynein light chain with the nuclear-pore complex
Philipp Stelter, Ruth Kunze, Dirk Flemming, Dominic Höpfner, Meikel Diepholz, Peter Philippsen, Bettina Böttcher & Ed Hurt Nature Cell Biology9, 788–796
(July 2007); doi:10.1038/ncb1604
| Summary | Full Text (HTML / PDF) |
letter Threonine phosphorylation post-translationally regulates protein secretion in Pseudomonas aeruginosa
Joseph D. Mougous, Casey A. Gifford, Talia L. Ramsdell & John J. Mekalanos Nature Cell Biology9, 797–803
(July 2007); doi:10.1038/ncb1605
| Summary | Full Text (HTML / PDF) |
news and views Threonine phosphorylation times bacterial secretion
Hemantha D. Kulasekara & Samuel I. Miller Nature Cell Biology9, 734–736
(July 2007); doi:10.1038/ncb0707-734
| Summary | Full Text (HTML / PDF) |
review Signal integration in the endoplasmic reticulum unfolded protein response
David Ron & Peter Walter Nature Reviews Molecular Cell Biology8, 519–529
(July 2007); doi:10.1038/nrm2199
| Summary | Full Text (HTML / PDF) |
article Bcl-6 mediates the germinal center B cell phenotype and lymphomagenesis through transcriptional repression of the DNA-damage sensor ATR8
Stella Maris Ranuncolo, Jose M Polo, Jamil Dierov, Michael Singer, Tracy Kuo, John Greally, Roland Green, Martin Carroll & Ari Melnick Nature Immunology8, 705–714
(July 2007); doi:10.1038/ni1478
| Summary | Full Text (HTML / PDF) |
article L-selectin-negative CCR7- effector and memory CD8+ T cells enter reactive lymph nodes and kill dendritic cells
Greta Guarda, Miroslav Hons, Silvia F Soriano, Alex Y Huang, Rosalind Polley, Alfonso Martín-Fontecha, Jens V Stein, Ronald N Germain, Antonio Lanzavecchia & Federica Sallusto Nature Immunology8, 743–752
(July 2007); doi:10.1038/ni1469
| Summary | Full Text (HTML / PDF) |
news and views Armed and ready: How effector T cells deploy in reactive lymph nodes to modulate immunity9
David W O'Neill & Nina Bhardwaj Nature Immunology8, 679–681
(July 2007); doi:10.1038/ni0707-679
| Summary | Full Text (HTML / PDF) |
review Life and death in peripheral T cells
Peter H. Krammer, Rüdiger Arnold & Inna N. Lavrik Nature Reviews Immunology7, 532–542
(July 2007); doi:10.1038/nri2115
| Summary | Full Text (HTML / PDF) |
review Assessing intraepithelial neoplasia and drug safety in cancer-preventive drug development
Gary J. Kelloff & Caroline C. Sigman Nature Reviews Cancer7, 508–518
(July 2007); doi:10.1038/nrc2154
| Summary | Full Text (HTML / PDF) |
technical report Tissue-specific and reversible RNA interference in transgenic mice
Ross A Dickins, Katherine McJunkin, Eva Hernando, Prem K Premsrirut, Valery Krizhanovsky, Darren J Burgess, Sang Yong Kim, Carlos Cordon-Cardo, Lars Zender, Gregory J Hannon & Scott W Lowe Nature Genetics39, 914–921
(July 2007); doi:10.1038/ng2045
| Summary | Full Text (HTML / PDF) |
technical report Toward simpler and faster genome-wide mutagenesis in mice
Sen Wu, Guoxin Ying, Qiang Wu & Mario R Capecchi Nature Genetics39, 922–930
(July 2007); doi:10.1038/ng2060
| Summary | Full Text (HTML / PDF) |
review The nuclear envelope and transcriptional control
Asifa Akhtar & Susan M. Gasser Nature Reviews Genetics8, 507–517
(July 2007); doi:10.1038/nrg2122
| Summary | Full Text (HTML / PDF) |
article RECK modulates Notch signaling during cortical neurogenesis by regulating ADAM10 activity
Teruyuki Muraguchi, Yujiro Takegami, Toshiyuki Ohtsuka, Shunsuke Kitajima, Ediriweera P S Chandana, Akira Omura, Takao Miki, Rei Takahashi, Naoya Matsumoto, Andreas Ludwig, Makoto Noda & Chiaki Takahashi Nature Neuroscience10, 838–845
(July 2007); doi:10.1038/nn1922
| Summary | Full Text (HTML / PDF) |
article UNC-46 is required for trafficking of the vesicular GABA transporter
Kim Schuske, Mark T Palfreyman, Shigeki Watanabe & Erik M Jorgensen Nature Neuroscience10, 846–853
(July 2007); doi:10.1038/nn1920
| Summary | Full Text (HTML / PDF) |
technical report From synapse to behavior: rapid modulation of defined neuronal types with engineered GABAA receptors
Peer Wulff, Thomas Goetz, Elli Leppä, Anni-Maija Linden, Massimiliano Renzi, Jerome D Swinny, Olga Y Vekovischeva, Werner Sieghart, Peter Somogyi, Esa R Korpi, Mark Farrant & William Wisden Nature Neuroscience10, 923–929
(July 2007); doi:10.1038/nn1927
| Summary | Full Text (HTML / PDF) |
review Intracellular amyloid-β in Alzheimer's disease
Frank M. LaFerla, Kim N. Green & Salvatore Oddo Nature Reviews Neuroscience8, 499–509
(July 2007); doi:10.1038/nrn2168
| Summary | Full Text (HTML / PDF) |
review Universal strategies in research and drug discovery based on protein-fragment complementation assays
Stephen W. Michnick, Po Hien Ear, Emily N. Manderson, Ingrid Remy & Eduard Stefan Nature Reviews Drug Discovery6, 569–582
(July 2007); doi:10.1038/nrd2311
| Summary | Full Text (HTML / PDF) |
brief communication Trawler: de novo regulatory motif discovery pipeline for chromatin immunoprecipitation
Laurence Ettwiller, Benedict Paten, Mirana Ramialison, Ewan Birney & Joachim Wittbrodt Nature Methods4, 563–565
(July 2007); doi:10.1038/nmeth1061
| Summary | Full Text (HTML / PDF) |
letter CD1d–lipid-antigen recognition by the semi-invariant NKT T-cell receptor
Natalie A. Borg, Kwok S. Wun, Lars Kjer-Nielsen, Matthew C. J. Wilce, Daniel G. Pellicci, Ruide Koh, Gurdyal S. Besra, Mandvi Bharadwaj, Dale I. Godfrey, James McCluskey & Jamie Rossjohn Nature448, 44–49
(5 July 2007); doi:10.1038/nature05907
| Summary | Full Text (HTML / PDF) |
news and views Immunology: How a T cell sees sugar
D. Branch Moody Nature448, 36–37
(5 July 2007); doi:10.1038/nature05890
| Full Text (HTML / PDF) |
letter Mutation of FIG4 causes neurodegeneration in the pale tremor mouse and patients with CMT4J
Clement Y. Chow, Yanling Zhang, James J. Dowling, Natsuko Jin, Maja Adamska, Kensuke Shiga, Kinga Szigeti, Michael E. Shy, Jun Li, Xuebao Zhang, James R. Lupski, Lois S. Weisman & Miriam H. Meisler Nature448, 68–72
(5 July 2007); doi:10.1038/nature05876
| Summary | Full Text (HTML / PDF) |
letter Novel neurotrophic factor CDNF protects and rescues midbrain dopamine neurons in vivo
Päivi Lindholm, Merja H. Voutilainen, Juha Laurén, Johan Peränen, Veli-Matti Leppänen, Jaan-Olle Andressoo, Maria Lindahl, Sanna Janhunen, Nisse Kalkkinen, Tõnis Timmusk, Raimo K. Tuominen & Mart Saarma Nature448, 73–77
(5 July 2007); doi:10.1038/nature05957
| Summary | Full Text (HTML / PDF) |
letter TRIC channels are essential for Ca2+ handling in intracellular stores
Masayuki Yazawa, Christopher Ferrante, Jue Feng, Kazuhiro Mio, Toshihiko Ogura, Miao Zhang, Pei-Hui Lin, Zui Pan, Shinji Komazaki, Kazuhiro Kato, Miyuki Nishi, Xiaoli Zhao, Noah Weisleder, Chikara Sato, Jianjie Ma & Hiroshi Takeshima Nature448, 78–82
(5 July 2007); doi:10.1038/nature05928
| Summary | Full Text (HTML / PDF) |
review The multifunctional nucleolus
François-Michel Boisvert, Silvana van Koningsbruggen, Joaquín Navascués & Angus I. Lamond Nature Reviews Molecular Cell Biology8, 574–585
(July 2007); doi:10.1038/nrm2184
| Summary | Full Text (HTML / PDF) |
perspective Lessons from 50 years of SOS DNA-damage-induced mutagenesis
Katharina Schlacher & Myron F. Goodman Nature Reviews Molecular Cell Biology8, 587–594
(July 2007); doi:10.1038/nrm2198
| Summary | Full Text (HTML / PDF) |
article Ligand-induced conformational changes allosterically activate Toll-like receptor 9
Eicke Latz, Anjali Verma, Alberto Visintin, Mei Gong, Cherilyn M Sirois, Dionne C G Klein, Brian G Monks, C James McKnight, Marc S Lamphier, W Paul Duprex, Terje Espevik & Douglas T Golenbock Nature Immunology8, 772–779
(July 2007); doi:10.1038/ni1479
| Summary | Full Text (HTML / PDF) |
news and views TLRs bent into shape
You-Me Kim, Melanie M Brinkmann & Hidde L Ploegh Nature Immunology8, 675–677
(July 2007); doi:10.1038/ni0707-675
| Summary | Full Text (HTML / PDF) |
review Control points in NKT-cell development
Dale I. Godfrey & Stuart P. Berzins Nature Reviews Immunology7, 505–518
(July 2007); doi:10.1038/nri2116
| Summary | Full Text (HTML / PDF) |
review CDC25 phosphatases in cancer cells: key players? Good targets?
Rose Boutros, Valérie Lobjois & Bernard Ducommun Nature Reviews Cancer7, 495–507
(July 2007); doi:10.1038/nrc2169
| Summary | Full Text (HTML / PDF) |
letter Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes
John A Todd et al. Nature Genetics39, 857–864
(July 2007); doi:10.1038/ng2068
| Summary | Full Text (HTML / PDF) |
brief communication Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility
Miles Parkes et al. Nature Genetics39, 830–832
(July 2007); doi:10.1038/ng2061
| Summary | Full Text (HTML / PDF) |
news and views Guilt beyond a reasonable doubt
David Altshuler & Mark Daly Nature Genetics39, 813–815
(July 2007); doi:10.1038/ng0707-813
| Summary | Full Text (HTML / PDF) |
review The versatile worm: genetic and genomic resources for Caenorhabditis elegans research
Igor Antoshechkin & Paul W. Sternberg Nature Reviews Genetics8, 518–532
(July 2007); doi:10.1038/nrg2105
| Summary | Full Text (HTML / PDF) |
article Numb and Numbl are required for maintenance of cadherin-based adhesion and polarity of neural progenitors
Mladen-Roko Rašin, Valeswara-Rao Gazula, Joshua J Breunig, Kenneth Y Kwan, Matthew B Johnson, Susan Liu-Chen, Hua-Shun Li, Lily Yeh Jan, Yuh-Nung Jan, Pasko Rakic & Nenad Šestan Nature Neuroscience10, 819–827
(July 2007); doi:10.1038/nn1924
| Summary | Full Text (HTML / PDF) |
news and views Numb, neurogenesis and epithelial polarity
Seonhee Kim & Chris A Walsh Nature Neuroscience10, 812–813
(July 2007); doi:10.1038/nn0707-812
| Summary | Full Text (HTML / PDF) |
review Post-translational modifications and regulation of the RAS superfamily of GTPases as anticancer targets
Panagiotis A. Konstantinopoulos, Michalis V. Karamouzis & Athanasios G. Papavassiliou Nature Reviews Drug Discovery6, 541–555
(July 2007); doi:10.1038/nrd2221
| Summary | Full Text (HTML / PDF) |
article Strategy for the fine characterization of glycosyltransferase specificity using isotopomer assembly
Hiromi Ito, Akihiko Kameyama, Takashi Sato, Masako Sukegawa, Hide-Ki Ishida & Hisashi Narimatsu Nature Methods4, 577–582
(July 2007); doi:10.1038/nmeth1050
| Summary | Full Text (HTML / PDF) |
letter Extension of Drosophila melanogaster life span with a GPCR peptide inhibitor
William W Ja, Anthony P West, Jr, Silvia L Delker, Pamela J Bjorkman, Seymour Benzer & Richard W Roberts Nature Chemical Biology3, 415–419
(July 2007); doi:10.1038/nchembio.2007.2
| Summary | Full Text (HTML / PDF) |
news and views Methuselah antagonist extends life span
Deirdre McGarrigle & Xin-Yun Huang Nature Chemical Biology3, 371–372
(July 2007); doi:10.1038/nchembio0707-371
| Full Text (HTML / PDF) |
