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The Research Library categorizes, and provides access to, all recent signaling-related research published in the Nature Publishing Group journals. The selection is deliberately broad to facilitate access to all research impacting on the signaling community. Both primary research and review articles are included, as are 'News and Views' articles.
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letter
Nanog safeguards pluripotency and mediates germline development
Ian Chambers et al.
Nature 450, 1230–1234
(20 December 2007); doi:10.1038/nature06403
| Summary | Full Text (HTML / PDF) |
letter
Isolation of rare circulating tumour cells in cancer patients by microchip technology
Sunitha Nagrath et al.
Nature 450, 1235–1239
(20 December 2007); doi:10.1038/nature06385
| Summary | Full Text (HTML / PDF) |
letter
Toll-like receptor signalling in macrophages links the autophagy pathway to phagocytosis
Miguel A. Sanjuan et al.
Nature 450, 1253–1257
(20 December 2007); doi:10.1038/nature06421
| Summary | Full Text (HTML / PDF) |
letter
Cdc48/p97 promotes reformation of the nucleus by extracting the kinase Aurora B from chromatin
Kristijan Ramadan et al.
Nature 450, 1258–1262
(20 December 2007); doi:10.1038/nature06388
| Summary | Full Text (HTML / PDF) |
article
SNX4 coordinates endosomal sorting of TfnR with dynein-mediated transport into the endocytic recycling compartment
Colin J. Traer et al.
Nature Cell Biology 9, 1370–1380
(December 2007); doi:10.1038/ncb1656
| Summary | Full Text (HTML / PDF) |
letter
MUC1 oncoprotein activates the IκB kinase β complex and constitutive NF-κB signalling
Rehan Ahmad et al.
Nature Cell Biology 9, 1419–1427
(December 2007); doi:10.1038/ncb1661
| Summary | Full Text (HTML / PDF) |
article
'Role reversal' for the receptor PAR1 in sepsis-induced vascular damage
Nicole C Kaneider et al.
Nature Immunology 8, 1303–1312
(December 2007); doi:10.1038/ni1525
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article
CD4+CD25+Foxp3+ regulatory T cells induce cytokine deprivation-mediated apoptosis of effector CD4+ T cells
Pushpa Pandiyan, Lixin Zheng, Satoru Ishihara, Jennifer Reed & Michael J Lenardo
Nature Immunology 8, 1353–1362
(December 2007); doi:10.1038/ni1536
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news and views
Competition for cytokines: Treg cells take all
Alexander Scheffold, Kenneth M Murphy & Thomas Höfer
Nature Immunology 8, 1285–1287
(December 2007); doi:10.1038/ni1207-1285
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article
T cell-encoded CD80 and 4-1BBL induce auto- and transcostimulation, resulting in potent tumor rejection
Matthias T Stephan et al.
Nature Medicine 13, 1440–1449
(December 2007); doi:10.1038/nm1676
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news and views
Building the bionic T cell
Drew M Pardoll
Nature Medicine 13, 1411–1413
(December 2007); doi:10.1038/nm1207-1411
| Summary | Full Text (HTML / PDF) |
letter
Acid-sensing ion channel-1 contributes to axonal degeneration in autoimmune inflammation of the central nervous system
Manuel A Friese et al.
Nature Medicine 13, 1483–1489
(December 2007); doi:10.1038/nm1668
| Summary | Full Text (HTML / PDF) |
review
CHK2 kinase: cancer susceptibility and cancer therapy — two sides of the same coin?
Laurent Antoni, Nayanta Sodha, Ian Collins & Michelle D. Garrett
Nature Reviews Cancer 7, 925–936
(December 2007); doi:10.1038/nrc2251
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article
Polyglutamine domain modulates the TBP–TFIIB interaction: implications for its normal function and neurodegeneration
Meyer J Friedman et al.
Nature Neuroscience 10, 1519–1528
(December 2007); doi:10.1038/nn2011
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progress
Molecular diversity of Dscam: recognition of molecular identity in neuronal wiring
Dietmar Schmucker
Nature Reviews Neuroscience 8, 915–920
(December 2007); doi:10.1038/nrn2256
| Summary | Full Text (HTML / PDF) |
letter
Redirecting lipoic acid ligase for cell surface protein labeling with small-molecule probes
Marta Fernández-Suárez et al.
Nature Biotechnology 25, 1483–1487
(December 2007); doi:10.1038/nbt1355
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article
p38 MAPK signaling regulates recruitment of Ash2L-containing methyltransferase complexes to specific genes during differentiation
Shravanti Rampalli et al.
Nature Structural & Molecular Biology 14, 1150–1156
(December 2007); doi:10.1038/nsmb1316
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article
Identification of heme as the ligand for the orphan nuclear receptors REV-ERBα and REV-ERBβ
Srilatha Raghuram et al.
Nature Structural & Molecular Biology 14, 1207–1213
(December 2007); doi:10.1038/nsmb1344
| Summary | Full Text (HTML / PDF) |
news and views
A monkey wrench in the kinase machine
Daniel J Leahy
Nature Structural & Molecular Biology 14, 1120–1121
(December 2007); doi:10.1038/nsmb1207-1120
| Full Text (HTML / PDF) |
scientific report
Ligand-independent activation of vascular endothelial growth factor receptor 1 by low-density lipoprotein
Ryosuke Usui, Masabumi Shibuya, Shun Ishibashi & Yoshiro Maru
EMBO Reports 8, 1155–1161
(December 2007); doi:10.1038/sj.embor.7401103
| Summary | Full Text (HTML / PDF) |
scientific report
Tripeptidyl peptidase II promotes fat formation in a conserved fashion
Renée M McKay, James P McKay, Jae Myoung Suh, Leon Avery & Jonathan M Graff
EMBO Reports 8, 1183–1189
(December 2007); doi:10.1038/sj.embor.7401086
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article
The structural basis of calcium transport by the calcium pump
Claus Olesen et al.
Nature 450, 1036–1042
(13 December 2007); doi:10.1038/nature06418
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article
Crystal structure of the sodium–potassium pump
J. Preben Morth et al.
Nature 450, 1043–1049
(13 December 2007); doi:10.1038/nature06419
| Summary | Full Text (HTML / PDF) |
letter
Crystal structure of the plasma membrane proton pump
Bjørn P. Pedersen, Morten J. Buch-Pedersen, J. Preben Morth, Michael G. Palmgren & Poul Nissen
Nature 450, 1111–1114
(13 December 2007); doi:10.1038/nature06417
| Summary | Full Text (HTML / PDF) |
news and views
Structural biology: Ion pumps made crystal clear
David C. Gadsby
Nature 450, 957–959
(13 December 2007); doi:10.1038/450957a
| Full Text (HTML / PDF) |
letter
Initiation of zebrafish haematopoiesis by the TATA-box-binding protein-related factor Trf3
Daniel O. Hart, Tamal Raha, Nathan D. Lawson & Michael R. Green
Nature 450, 1082–1085
(13 December 2007); doi:10.1038/nature06349
| Summary | Full Text (HTML / PDF) |
letter
A viral microRNA functions as an orthologue of cellular miR-155
Eva Gottwein et al.
Nature 450, 1096–1099
(13 December 2007); doi:10.1038/nature05992
| Summary | Full Text (HTML / PDF) |
article
Arf6 and microtubules in adhesion-dependent trafficking of lipid rafts
Nagaraj Balasubramanian, David W. Scott, J. David Castle, James E. Casanova & Martin Alexander Schwartz
Nature Cell Biology 9, 1381–1391
(December 2007); doi:10.1038/ncb1657
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review
Synergistic control of cell adhesion by integrins and syndecans
Mark R. Morgan, Martin J. Humphries & Mark D. Bass
Nature Reviews Molecular Cell Biology 8, 957–969
(December 2007); doi:10.1038/nrm2289
| Summary | Full Text (HTML / PDF) |
article
Natural killer cell trafficking in vivo requires a dedicated sphingosine 1-phosphate receptor
Thierry Walzer et al.
Nature Immunology 8, 1337–1344
(December 2007); doi:10.1038/ni1523
| Summary | Full Text (HTML / PDF) |
article
NKG2D signaling is coupled to the interleukin 15 receptor signaling pathway
Tiffany Horng, Jelena S Bezbradica & Ruslan Medzhitov
Nature Immunology 8, 1345–1352
(December 2007); doi:10.1038/ni1524
| Summary | Full Text (HTML / PDF) |
news and views
Unexpected partnership between IL-15 and DAP10
Francesco Colucci
Nature Immunology 8, 1289–1291
(December 2007); doi:10.1038/ni1207-1289
| Full Text (HTML / PDF) |
review
Engulfment of apoptotic cells: signals for a good meal
Kodi S. Ravichandran & Ulrike Lorenz
Nature Reviews Immunology 7, 964–974
(December 2007); doi:10.1038/nri2214
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article
Therapeutic differentiation and maturation of lymphatic vessels after lymph node dissection and transplantation
Tuomas Tammela et al.
Nature Medicine 13, 1458–1466
(December 2007); doi:10.1038/nm1689
| Summary | Full Text (HTML / PDF) |
article
Pim-1 regulates cardiomyocyte survival downstream of Akt
John A Muraski et al.
Nature Medicine 13, 1467–1475
(December 2007); doi:10.1038/nm1671
| Summary | Full Text (HTML / PDF) |
letter
PPAR-γ regulates osteoclastogenesis in mice
Yihong Wan, Ling-Wa Chong & Ronald M Evans
Nature Medicine 13, 1496–1503
(December 2007); doi:10.1038/nm1672
| Summary | Full Text (HTML / PDF) |
review
Oncogenes and tumour suppressors take on centrosomes
Kenji Fukasawa
Nature Reviews Cancer 7, 911–924
(December 2007); doi:10.1038/nrc2249
| Summary | Full Text (HTML / PDF) |
review
Glutamate transporters: confining runaway excitation by shaping synaptic transmission
Anastassios V. Tzingounis & Jacques I. Wadiche
Nature Reviews Neuroscience 8, 935–947
(December 2007); doi:10.1038/nrn2274
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article
Endogenous microRNA can be broadly exploited to regulate transgene expression according to tissue, lineage and differentiation state
Brian D Brown et al.
Nature Biotechnology 25, 1457–1467
(December 2007); doi:10.1038/nbt1372
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article
A YY1–INO80 complex regulates genomic stability through homologous recombination-based repair
Su Wu et al.
Nature Structural & Molecular Biology 14, 1165–1172
(December 2007); doi:10.1038/nsmb1332
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article
Stability of the proteasome can be regulated allosterically through engagement of its proteolytic active sites
Maurits F Kleijnen et al.
Nature Structural & Molecular Biology 14, 1180–1188
(December 2007); doi:10.1038/nsmb1335
| Summary | Full Text (HTML / PDF) |
scientific report
Src kinase modulates the activation, transport and signalling dynamics of fibroblast growth factor receptors
Emma Sandilands, Shiva Akbarzadeh, Anna Vecchione, David G McEwan, Margaret C Frame & John K Heath
EMBO Reports 8, 1162–1169
(December 2007); doi:10.1038/sj.embor.7401097
| Summary | Full Text (HTML / PDF) |
scientific report
Regulation of flowering time by the protein arginine methyltransferase AtPRMT10
Lifang Niu, Falong Lu, Yanxi Pei, Chunyan Liu & Xiaofeng Cao
EMBO Reports 8, 1190–1195
(December 2007); doi:10.1038/sj.embor.7401111
| Summary | Full Text (HTML / PDF) |
article
Bv8 regulates myeloid-cell-dependent tumour angiogenesis
Farbod Shojaei et al.
Nature 450, 825–831
(6 December 2007); doi:10.1038/nature06348
| Summary | Full Text (HTML / PDF) |
letter
Adaptive immunity maintains occult cancer in an equilibrium state
Catherine M. Koebel et al.
Nature 450, 903–907
(6 December 2007); doi:10.1038/nature06309
| Summary | Full Text (HTML / PDF) |
news and views
Cancer: Immune pact with the enemy
Cornelis J. M. Melief
Nature 450, 803–804
(6 December 2007); doi:10.1038/nature06363
| Full Text (HTML / PDF) |
article
Fibroblast-led collective invasion of carcinoma cells with differing roles for RhoGTPases in leading and following cells
Cedric Gaggioli et al.
Nature Cell Biology 9, 1392–1400
(December 2007); doi:10.1038/ncb1658
| Summary | Full Text (HTML / PDF) |
news and views
Leading the charge
Derek C. Radisky
Nature Cell Biology 9, 1341–1342
(December 2007); doi:10.1038/ncb1207-1341
| Summary | Full Text (HTML / PDF) |
review
TGFβ–SMAD signal transduction: molecular specificity and functional flexibility
Bernhard Schmierer & Caroline S. Hill
Nature Reviews Molecular Cell Biology 8, 970–982
(December 2007); doi:10.1038/nrm2297
| Summary | Full Text (HTML / PDF) |
article
Interleukins 27 and 6 induce STAT3-mediated T cell production of interleukin 10
Jason S Stumhofer et al.
Nature Immunology 8, 1363–1371
(December 2007); doi:10.1038/ni1537
| Summary | Full Text (HTML / PDF) |
article
Suppression of autoimmune inflammation of the central nervous system by interleukin 10 secreted by interleukin 27-stimulated T cells
Denise C Fitzgerald et al.
Nature Immunology 8, 1372–1379
(December 2007); doi:10.1038/ni1540
| Summary | Full Text (HTML / PDF) |
article
A dominant function for interleukin 27 in generating interleukin 10-producing anti-inflammatory T cells
Amit Awasthi et al.
Nature Immunology 8, 1380–1389
(December 2007); doi:10.1038/ni1541
| Summary | Full Text (HTML / PDF) |
article
TGF-β and IL-6 drive the production of IL-17 and IL-10 by T cells and restrain TH-17 cell-mediated pathology
Mandy J McGeachy, Kristian S Bak-Jensen, Yi Chen, Cristina M Tato, Wendy Blumenschein, Terrill McClanahan & Daniel J Cua
Nature Immunology 8, 1390–1397
(December 2007); doi:10.1038/ni1539
| Summary | Full Text (HTML / PDF) |
news and views
IL-10 or not IL-10: that is the question
Dragana Jankovic & Giorgio Trinchieri
Nature Immunology 8, 1281–1283
(December 2007); doi:10.1038/ni1207-1281
| Full Text (HTML / PDF) |
perspective
Role of autophagy in cancer
Robin Mathew, Vassiliki Karantza-Wadsworth & Eileen White
Nature Reviews Cancer 7, 961–967
(December 2007); doi:10.1038/nrc2254
| Summary | Full Text (HTML / PDF) |
article
ATP-sensitive potassium channels mediate survival during infection in mammals and insects
Ben Croker et al.
Nature Genetics 39, 1453–1460
(December 2007); doi:10.1038/ng.2007.25
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news and views
Sudden and unexpected
Rudi Balling
Nature Genetics 39, 1422–1423
(December 2007); doi:10.1038/ng1207-1422
| Full Text (HTML / PDF) |
letter
Loss of Trim24 (Tif1α) gene function confers oncogenic activity to retinoic acid receptor alpha
Konstantin Khetchoumian et al.
Nature Genetics 39, 1500–1506
(December 2007); doi:10.1038/ng.2007.15
| Summary | Full Text (HTML / PDF) |
review
Cooperation of signalling pathways in embryonic mammary gland development
Gertraud W. Robinson
Nature Reviews Genetics 8, 963–972
(December 2007); doi:10.1038/nrg2227
| Summary | Full Text (HTML / PDF) |
article
RGS2 modulates coupling between GABAB receptors and GIRK channels in dopamine neurons of the ventral tegmental area
Gwenaël Labouèbe et al.
Nature Neuroscience 10, 1559–1568
(December 2007); doi:10.1038/nn2006
| Summary | Full Text (HTML / PDF) |
brief communication
Homeostatic regulation of MeCP2 expression by a CREB-induced microRNA
Matthew E Klein, Daniel T Lioy, Lin Ma, Soren Impey, Gail Mandel & Richard H Goodman
Nature Neuroscience 10, 1513–1514
(December 2007); doi:10.1038/nn2010
| Summary | Full Text (HTML / PDF) |
review
Regulation of ion transport proteins by membrane phosphoinositides
Nikita Gamper & Mark S. Shapiro
Nature Reviews Neuroscience 8, 921–934
(December 2007); doi:10.1038/nrn2257
| Summary | Full Text (HTML / PDF) |
review
Interferons at age 50: past, current and future impact on biomedicine
Ernest C. Borden et al.
Nature Reviews Drug Discovery 6, 975–990
(December 2007); doi:10.1038/nrd2422
| Summary | Full Text (HTML / PDF) |
article
Using expression profiling data to identify human microRNA targets
Jim C Huang et al.
Nature Methods 4, 1045–1049
(December 2007); doi:10.1038/nmeth1130
| Summary | Full Text (HTML / PDF) |
article
Genetically encoded molecules for inducibly inactivating CaV channels
Tingting Yang, Yasir Suhail, Stanislava Dalton, Timothy Kernan & Henry M Colecraft
Nature Chemical Biology 3, 795–804
(December 2007); doi:10.1038/nchembio.2007.42
| Summary | Full Text (HTML / PDF) |
news and views
Chemical genetic modification of Ca2+ channel activity
Michael Nitabach
Nature Chemical Biology 3, 754–755
(December 2007); doi:10.1038/nchembio1207-754
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