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February 2008
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The Research Library categorizes, and provides access to, all recent signaling-related research published in the Nature Publishing Group journals. The selection is deliberately broad to facilitate access to all research impacting on the signaling community. Both primary research and review articles are included, as are 'News and Views' articles.
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article
Proteomic analysis of active multiple sclerosis lesions reveals therapeutic targets
May H. Han et al.
Nature 451, 1076–1081
(28 February 2008); doi:10.1038/nature06559
| Summary | Full Text (HTML / PDF) |
letter
Resistance to therapy caused by intragenic deletion in BRCA2
Stacey L. Edwards et al.
Nature 451, 1111–1115
(28 February 2008); doi:10.1038/nature06548
| Summary | Full Text (HTML / PDF) |
letter
Secondary mutations as a mechanism of cisplatin resistance in BRCA2-mutated cancers
Wataru Sakai et al.
Nature 451, 1116–1120
(28 February 2008); doi:10.1038/nature06633
| Summary | Full Text (HTML / PDF) |
news and views
Cancer: Crossing over to drug resistance
David M. Livingston & Daniel P. Silver
Nature 451, 1066–1067
(28 February 2008); doi:10.1038/4511066a
| Full Text (HTML / PDF) |
letter
Gamete formation without meiosis in Arabidopsis
Maruthachalam Ravi, Mohan P. A. Marimuthu & Imran Siddiqi
Nature 451, 1121–1124
(28 February 2008); doi:10.1038/nature06557
| Summary | Full Text (HTML / PDF) |
news and views
Biotechnology: A hold on plant meiosis
Peter J. van Dijk
Nature 451, 1063–1064
(28 February 2008); doi:10.1038/4511063a
| Full Text (HTML / PDF) |
letter
Regulation of progenitor cell proliferation and granulocyte function by microRNA-223
Jonathan B. Johnnidis et al.
Nature 451, 1125–1129
(28 February 2008); doi:10.1038/nature06607
| Summary | Full Text (HTML / PDF) |
article
TBL1–TBLR1 and β-catenin recruit each other to Wnt target-gene promoter for transcription activation and oncogenesis
Jiong Li & Cun-Yu Wang
Nature Cell Biology 10, 160–169
(February 2008); doi:10.1038/ncb1684
| Summary | Full Text (HTML / PDF) |
letter
Sterol-dependent endocytosis mediates post-cytokinetic acquisition of PIN2 auxin efflux carrier polarity
Shuzhen Men et al.
Nature Cell Biology 10, 237–244
(February 2008); doi:10.1038/ncb1686
| Summary | Full Text (HTML / PDF) |
review
Inositol derivatives: evolution and functions
Robert H. Michell
Nature Reviews Molecular Cell Biology 9, 151–161
(February 2008); doi:10.1038/nrm2334
| Summary | Full Text (HTML / PDF) |
article
Smad3 and NFAT cooperate to induce Foxp3 expression through its enhancer
Yukiko Tone, Keiji Furuuchi, Yoshitsugu Kojima, Mark L Tykocinski, Mark I Greene & Masahide Tone
Nature Immunology 9, 194–202
(February 2008); doi:10.1038/ni1549
| Summary | Full Text (HTML / PDF) |
news and views
What turns on Foxp3?
Harald von Boehmer & Jens Nolting
Nature Immunology 9, 121–122
(February 2008); doi:10.1038/ni0208-121
| Full Text (HTML / PDF) |
article
Dual role of proapoptotic BAD in insulin secretion and beta cell survival
Nika N Danial et al.
Nature Medicine 14, 144–153
(February 2008); doi:10.1038/nm1717
| Summary | Full Text (HTML / PDF) |
article
Beta-catenin stabilization extends regulatory T cell survival and induces anergy in nonregulatory T cells
Yi Ding, Shiqian Shen, Andreia C Lino, Maria A Curotto de Lafaille & Juan J Lafaille
Nature Medicine 14, 162–169
(February 2008); doi:10.1038/nm1707
| Summary | Full Text (HTML / PDF) |
news and views
Safer, longer-lasting regulatory T cells with β-catenin
Jeffrey A Bluestone & Matthias Hebrok
Nature Medicine 14, 118–119
(February 2008); doi:10.1038/nm0208-118
| Summary | Full Text (HTML / PDF) |
perspective
Is cell competition relevant to cancer?
Eduardo Moreno
Nature Reviews Cancer 8, 141–147
(February 2008); doi:10.1038/nrc2252
| Summary | Full Text (HTML / PDF) |
review
Deconstructing stem cell self-renewal: genetic insights into cell-cycle regulation
Keith W. Orford & David T. Scadden
Nature Reviews Genetics 9, 115–128
(February 2008); doi:10.1038/nrg2269
| Summary | Full Text (HTML / PDF) |
article
NGF-promoted axon growth and target innervation requires GITRL–GITR signaling
Gerard W O'Keeffe, Humberto Gutierrez, Pier Paolo Pandolfi, Carlo Riccardi & Alun M Davies
Nature Neuroscience 11, 135–142
(February 2008); doi:10.1038/nn2034
| Summary | Full Text (HTML / PDF) |
review
Targeting the murine serotonin transporter: insights into human neurobiology
Dennis L. Murphy & Klaus-Peter Lesch
Nature Reviews Neuroscience 9, 85–96
(February 2008); doi:10.1038/nrn2284
| Summary | Full Text (HTML / PDF) |
review
Carbonic anhydrases: novel therapeutic applications for inhibitors and activators
Claudiu T. Supuran
Nature Reviews Drug Discovery 7, 168–181
(February 2008); doi:10.1038/nrd2467
| Summary | Full Text (HTML / PDF) |
article
The functional response of upstream DNA to dynamic supercoiling in vivo
Fedor Kouzine, Suzanne Sanford, Zichrini Elisha-Feil & David Levens
Nature Structural & Molecular Biology 15, 146–154
(February 2008); doi:10.1038/nsmb.1372
| Summary | Full Text (HTML / PDF) |
news and views
DNA torsional stress propagates through chromatin fiber and participates in transcriptional regulation
Christophe Lavelle
Nature Structural & Molecular Biology 15, 123–125
(February 2008); doi:10.1038/nsmb0208-123
| Full Text (HTML / PDF) |
review
Complement evasion by human pathogens
John D. Lambris, Daniel Ricklin & Brian V. Geisbrecht
Nature Reviews Microbiology 6, 132–142
(February 2008); doi:10.1038/nrmicro1824
| Summary | Full Text (HTML / PDF) |
brief communication
A secreted luciferase for ex vivo monitoring of in vivo processes
Thomas Wurdinger et al.
Nature Methods 5, 171–173
(February 2008); doi:10.1038/nmeth.1177
| Summary | Full Text (HTML / PDF) |
article
Conformational cross-talk between α2A-adrenergic and μ-opioid receptors controls cell signaling
Jean-Pierre Vilardaga, Viacheslav O Nikolaev, Kristina Lorenz, Sébastien Ferrandon, Zhenjie Zhuang & Martin J Lohse
Nature Chemical Biology 4, 126–131
(February 2008); doi:10.1038/nchembio.64
| Summary | Full Text (HTML / PDF) |
article
Phosphoinositide signalling links O-GlcNAc transferase to insulin resistance
Xiaoyong Yang et al.
Nature 451, 964–969
(21 February 2008); doi:10.1038/nature06668
| Summary | Full Text (HTML / PDF) |
letter
A role for adult TLX-positive neural stem cells in learning and behaviour
Chun-Li Zhang, Yuhua Zou, Weimin He, Fred H. Gage & Ronald M. Evans
Nature 451, 1004–1007
(21 February 2008); doi:10.1038/nature06562
| Summary | Full Text (HTML / PDF) |
letter
HIF-independent regulation of VEGF and angiogenesis by the transcriptional coactivator PGC-1α
Zoltan Arany et al.
Nature 451, 1008–1012
(21 February 2008); doi:10.1038/nature06613
| Summary | Full Text (HTML / PDF) |
letter
A PtdIns4,5P2-regulated nuclear poly(A) polymerase controls expression of select mRNAs
David L. Mellman et al.
Nature 451, 1013–1017
(21 February 2008); doi:10.1038/nature06666
| Summary | Full Text (HTML / PDF) |
review
Translating molecular discoveries into new therapies for atherosclerosis
Daniel J. Rader & Alan Daugherty
Nature 451, 904–913
(21 February 2008); doi:10.1038/nature06796
| Summary | Full Text (HTML / PDF) |
review
Triggers, targets and treatments for thrombosis
Nigel Mackman
Nature 451, 914–918
(21 February 2008); doi:10.1038/nature06797
| Summary | Full Text (HTML / PDF) |
review
Tackling heart failure in the twenty-first century
James O. Mudd & David A. Kass
Nature 451, 919–928
(21 February 2008); doi:10.1038/nature06798
| Summary | Full Text (HTML / PDF) |
review
The developmental genetics of congenital heart disease
Benoit G. Bruneau
Nature 451, 943–948
(21 February 2008); doi:10.1038/nature06801
| Summary | Full Text (HTML / PDF) |
progress
The search for new cardiovascular biomarkers
Robert E. Gerszten & Thomas J. Wang
Nature 451, 949–952
(21 February 2008); doi:10.1038/nature06802
| Summary | Full Text (HTML / PDF) |
letter
A β-catenin gradient links the clock and wavefront systems in mouse embryo segmentation
Alexander Aulehla et al.
Nature Cell Biology 10, 186–193
(February 2008); doi:10.1038/ncb1679
| Summary | Full Text (HTML / PDF) |
letter
Nanog maintains pluripotency of mouse embryonic stem cells by inhibiting NFκB and cooperating with Stat3
Josema Torres & Fiona M. Watt
Nature Cell Biology 10, 194–201
(February 2008); doi:10.1038/ncb1680
| Summary | Full Text (HTML / PDF) |
review
Cellular cholesterol trafficking and compartmentalization
Elina Ikonen
Nature Reviews Molecular Cell Biology 9, 125–138
(February 2008); doi:10.1038/nrm2336
| Summary | Full Text (HTML / PDF) |
article
Interleukin 17-producing T helper cells and interleukin 17 orchestrate autoreactive germinal center development in autoimmune BXD2 mice
Hui-Chen Hsu et al.
Nature Immunology 9, 166–175
(February 2008); doi:10.1038/ni1552
| Summary | Full Text (HTML / PDF) |
news and views
IL-17 drives germinal center B cells?
David Tarlinton
Nature Immunology 9, 124–126
(February 2008); doi:10.1038/ni0208-124
| Full Text (HTML / PDF) |
review
Micromanagement of the immune system by microRNAs
Harvey F. Lodish, Beiyan Zhou, Gwen Liu & Chang-Zheng Chen
Nature Reviews Immunology 8, 120–130
(February 2008); doi:10.1038/nri2252
| Summary | Full Text (HTML / PDF) |
letter
Oxidative damage-induced inflammation initiates age-related macular degeneration
Joe G Hollyfield et al.
Nature Medicine 14, 194–198
(February 2008); doi:10.1038/nm1709
| Summary | Full Text (HTML / PDF) |
review
Ral GTPases and cancer: linchpin support of the tumorigenic platform
Brian O. Bodemann & Michael A. White
Nature Reviews Cancer 8, 133–140
(February 2008); doi:10.1038/nrc2296
| Summary | Full Text (HTML / PDF) |
article
Action potential generation requires a high sodium channel density in the axon initial segment
Maarten H P Kole, Susanne U Ilschner, Björn M Kampa, Stephen R Williams, Peter C Ruben & Greg J Stuart
Nature Neuroscience 11, 178–186
(February 2008); doi:10.1038/nn2040
| Summary | Full Text (HTML / PDF) |
brief communication
Biosynthesis and processing of endogenous BDNF: CNS neurons store and secrete BDNF, not pro-BDNF
Tomoya Matsumoto et al.
Nature Neuroscience 11, 131–133
(February 2008); doi:10.1038/nn2038
| Summary | Full Text (HTML / PDF) |
review
Actin-binding proteins take the reins in growth cones
Chi W. Pak, Kevin C. Flynn & James R. Bamburg
Nature Reviews Neuroscience 9, 136–147
(February 2008); doi:10.1038/nrn2236
| Summary | Full Text (HTML / PDF) |
letter
Fluorogen-activating single-chain antibodies for imaging cell surface proteins
Christopher Szent-Gyorgyi et al.
Nature Biotechnology 26, 235–240
(February 2008); doi:10.1038/nbt1368
| Summary | Full Text (HTML / PDF) |
brief communication
Epitope tagging of endogenous proteins for genome-wide ChIP-chip studies
Xiaodong Zhang et al.
Nature Methods 5, 163–165
(February 2008); doi:10.1038/nmeth1170
| Summary | Full Text (HTML / PDF) |
article
Dual control of nuclear EIN3 by bifurcate MAPK cascades in C2H4 signalling
Sang-Dong Yoo, Young-Hee Cho, Guillaume Tena, Yan Xiong & Jen Sheen
Nature 451, 789–795
(14 February 2008); doi:10.1038/nature06543
| Summary | Full Text (HTML / PDF) |
letter
Removal of phospho-head groups of membrane lipids immobilizes voltage sensors of K+ channels
Yanping Xu, Yajamana Ramu & Zhe Lu
Nature 451, 826–829
(14 February 2008); doi:10.1038/nature06618
| Summary | Full Text (HTML / PDF) |
letter
A modular switch for spatial Ca2+ selectivity in the calmodulin regulation of CaV channels
Ivy E. Dick, Michael R. Tadross, Haoya Liang, Lai Hock Tay, Wanjun Yang & David T. Yue
Nature 451, 830–834
(14 February 2008); doi:10.1038/nature06529
| Summary | Full Text (HTML / PDF) |
letter
Co-option of a default secretory pathway for plant immune responses
Chian Kwon et al.
Nature 451, 835–840
(14 February 2008); doi:10.1038/nature06545
| Summary | Full Text (HTML / PDF) |
letter
The structural basis of protein acetylation by the p300/CBP transcriptional coactivator
Xin Liu et al.
Nature 451, 846–850
(14 February 2008); doi:10.1038/nature06546
| Summary | Full Text (HTML / PDF) |
article
ERK promotes tumorigenesis by inhibiting FOXO3a via MDM2-mediated degradation
Jer-Yen Yang et al.
Nature Cell Biology 10, 138–148
(February 2008); doi:10.1038/ncb1676
| Summary | Full Text (HTML / PDF) |
news and views
ERK and MDM2 prey on FOXO3a
Wensheng Yang, Nathan G. Dolloff & Wafik S. El-Deiry
Nature Cell Biology 10, 125–126
(February 2008); doi:10.1038/ncb0208-125
| Summary | Full Text (HTML / PDF) |
letter
The microRNAs miR-373 and miR-520c promote tumour invasion and metastasis
Qihong Huang et al.
Nature Cell Biology 10, 202–210
(February 2008); doi:10.1038/ncb1681
| Summary | Full Text (HTML / PDF) |
review
Membrane lipids: where they are and how they behave
Gerrit van Meer, Dennis R. Voelker & Gerald W. Feigenson
Nature Reviews Molecular Cell Biology 9, 112–124
(February 2008); doi:10.1038/nrm2330
| Summary | Full Text (HTML / PDF) |
article
Transcription factor EBF restricts alternative lineage options and promotes B cell fate commitment independently of Pax5
Jagan M R Pongubala et al.
Nature Immunology 9, 203–215
(February 2008); doi:10.1038/ni1555
| Summary | Full Text (HTML / PDF) |
review
Of lineage and legacy: the development of mammalian hematopoietic stem cells
Elaine Dzierzak & Nancy A Speck
Nature Immunology 9, 129–136
(February 2008); doi:10.1038/ni1560
| Summary | Full Text (HTML / PDF) |
perpsective
The reverse stop-signal model for CTLA4 function
Christopher E. Rudd
Nature Reviews Immunology 8, 153–160
(February 2008); doi:10.1038/nri2253
| Summary | Full Text (HTML / PDF) |
letter
Prevention of the neurocristopathy Treacher Collins syndrome through inhibition of p53 function
Natalie C Jones et al.
Nature Medicine 14, 125–133
(February 2008); doi:10.1038/nm1725
| Summary | Full Text (HTML / PDF) |
news and views
Saving face: rescuing a craniofacial birth defect
Sonja Jane McKeown & Marianne Bronner-Fraser
Nature Medicine 14, 115–116
(February 2008); doi:10.1038/nm0208-115
| Summary | Full Text (HTML / PDF) |
review
New approaches for imaging tumour responses to treatment
Kevin Brindle
Nature Reviews Cancer 8, 94–107
(February 2008); doi:10.1038/nrc2289
| Summary | Full Text (HTML / PDF) |
article
SK2 channel plasticity contributes to LTP at Schaffer collateral–CA1 synapses
Mike T Lin, Rafael Luján, Masahiko Watanabe, John P Adelman & James Maylie
Nature Neuroscience 11, 170–177
(February 2008); doi:10.1038/nn2041
| Summary | Full Text (HTML / PDF) |
review
The nitrate–nitrite–nitric oxide pathway in physiology and therapeutics
Jon O. Lundberg, Eddie Weitzberg & Mark T. Gladwin
Nature Reviews Drug Discovery 7, 156–167
(February 2008); doi:10.1038/nrd2466
| Summary | Full Text (HTML / PDF) |
article
Protein unfolding by a AAA+ protease is dependent on ATP-hydrolysis rates and substrate energy landscapes
Andreas Martin, Tania A Baker & Robert T Sauer
Nature Structural & Molecular Biology 15, 139–145
(February 2008); doi:10.1038/nsmb.1380
| Summary | Full Text (HTML / PDF) |
review
Inter-kingdom signalling: communication between bacteria and their hosts
David T. Hughes & Vanessa Sperandio
Nature Reviews Microbiology 6, 111–120
(February 2008); doi:10.1038/nrmicro1836
| Summary | Full Text (HTML / PDF) |
review
Protein production and purification
Structural Genomics Consortium et al.
Nature Methods 5, 135–146
(February 2008); doi:10.1038/nmeth.f.202
| Summary | Full Text (HTML / PDF) |
article
A forward chemical genetic screen reveals an inhibitor of the Mre11–Rad50–Nbs1 complex
Aude Dupré et al.
Nature Chemical Biology 4, 119–125
(February 2008); doi:10.1038/nchembio.63
| Summary | Full Text (HTML / PDF) |
news and views
Small molecule versus DNA repair nanomachine
James T Stivers
Nature Chemical Biology 4, 86–88
(February 2008); doi:10.1038/nchembio0208-86
| Full Text (HTML / PDF) |
letter
TANK-binding kinase-1 delineates innate and adaptive immune responses to DNA vaccines
Ken J. Ishii et al.
Nature 451, 725–729
(7 February 2008); doi:10.1038/nature06537
| Summary | Full Text (HTML / PDF) |
letter
Drosophila Pgc protein inhibits P-TEFb recruitment to chromatin in primordial germ cells
Kazuko Hanyu-Nakamura, Hiroko Sonobe-Nojima, Akie Tanigawa, Paul Lasko & Akira Nakamura
Nature 451, 730–733
(7 February 2008); doi:10.1038/nature06498
| Summary | Full Text (HTML / PDF) |
letter
Cell cycle control of centromeric repeat transcription and heterochromatin assembly
Ee Sin Chen, Ke Zhang, Estelle Nicolas, Hugh P. Cam, Martin Zofall & Shiv I. S. Grewal
Nature 451, 734–737
(7 February 2008); doi:10.1038/nature06561
| Summary | Full Text (HTML / PDF) |
article
PDK1 regulates cancer cell motility by antagonising inhibition of ROCK1 by RhoE
Sophie Pinner & Erik Sahai
Nature Cell Biology 10, 127–137
(February 2008); doi:10.1038/ncb1675
| Summary | Full Text (HTML / PDF) |
review
Principles of bioactive lipid signalling: lessons from sphingolipids
Yusuf A. Hannun & Lina M. Obeid
Nature Reviews Molecular Cell Biology 9, 139–150
(February 2008); doi:10.1038/nrm2329
| Summary | Full Text (HTML / PDF) |
article
Acute upregulation of an NKG2D ligand promotes rapid reorganization of a local immune compartment with pleiotropic effects on carcinogenesis
Jessica Strid et al.
Nature Immunology 9, 146–154
(February 2008); doi:10.1038/ni1556
| Summary | Full Text (HTML / PDF) |
news and views
Stress gets under your skin
Daniel M Andrews & Mark J Smyth
Nature Immunology 9, 119–120
(February 2008); doi:10.1038/ni0208-119
| Full Text (HTML / PDF) |
review
Phagocytosis and comparative innate immunity: learning on the fly
Lynda M. Stuart & R. Alan Ezekowitz
Nature Reviews Immunology 8, 131–141
(February 2008); doi:10.1038/nri2240
| Summary | Full Text (HTML / PDF) |
letter
Dok1 mediates high-fat diet-induced adipocyte hypertrophy and obesity through modulation of PPAR-γ phosphorylation
Tetsuya Hosooka et al.
Nature Medicine 14, 188–193
(February 2008); doi:10.1038/nm1706
| Summary | Full Text (HTML / PDF) |
review
Diagnosing and exploiting cancer's addiction to blocks in apoptosis
Anthony G. Letai
Nature Reviews Cancer 8, 121–132
(February 2008); doi:10.1038/nrc2297
| Summary | Full Text (HTML / PDF) |
letter
Mutations in pericentrin cause Seckel syndrome with defective ATR-dependent DNA damage signaling
Elen Griffith et al.
Nature Genetics 40, 232–236
(February 2008); doi:10.1038/ng.2007.80
| Summary | Full Text (HTML / PDF) |
review
Epigenetic events in mammalian germ-cell development: reprogramming and beyond
Hiroyuki Sasaki & Yasuhisa Matsui
Nature Reviews Genetics 9, 129–140
(February 2008); doi:10.1038/nrg2295
| Summary | Full Text (HTML / PDF) |
article
Anandamide inhibits metabolism and physiological actions of 2-arachidonoylglycerol in the striatum
Mauro Maccarrone et al.
Nature Neuroscience 11, 152–159
(February 2008); doi:10.1038/nn2042
| Summary | Full Text (HTML / PDF) |
news and views
Why endocannabinoids are not all alike
Vincenzo Di Marzo & Luigia Cristino
Nature Neuroscience 11, 124–126
(February 2008); doi:10.1038/nn0208-124
| Full Text (HTML / PDF) |
brief communication
Switching constant domains enhances agonist activities of antibodies to a thrombopoietin receptor
Masayuki Kai et al.
Nature Biotechnology 26, 209–211
(February 2008); doi:10.1038/nbt1376
| Summary | Full Text (HTML / PDF) |
article
Crystal structure of the multifunctional Gβ5–RGS9 complex
Matthew L Cheever, Jason T Snyder, Svetlana Gershburg, David P Siderovski, T Kendall Harden & John Sondek
Nature Structural & Molecular Biology 15, 155–162
(February 2008); doi:10.1038/nsmb.1377
| Summary | Full Text (HTML / PDF) |
article
High-content single-cell drug screening with phosphospecific flow cytometry
Peter O Krutzik, Janelle M Crane, Matthew R Clutter & Garry P Nolan
Nature Chemical Biology 4, 132–142
(February 2008); doi:10.1038/nchembio.2007.59
| Summary | Full Text (HTML / PDF) |
scientific report
A selective PIKfyve inhibitor blocks PtdIns(3,5)P2 production and disrupts endomembrane transport and retroviral budding
Harold B J Jefferies et al.
EMBO Reports 9, 164–170
(February 2008); doi:10.1038/sj.embor.7401155
| Summary | Full Text (HTML / PDF) |
scientific report
CARM1 promotes adipocyte differentiation by coactivating PPARγ
Neelu Yadav et al.
EMBO Reports 9, 193–198
(February 2008); doi:10.1038/sj.embor.7401151
| Summary | Full Text (HTML / PDF) |
scientific report
Conformational switch of angiotensin II type 1 receptor underlying mechanical stress-induced activation
Noritaka Yasuda et al.
EMBO Reports 9, 179–186
(February 2008); doi:10.1038/sj.embor.7401157
| Summary | Full Text (HTML / PDF) |
letter
NLRX1 is a regulator of mitochondrial antiviral immunity
Chris B. Moore et al.
Nature 451, 573–577
(31 January 2008); doi:10.1038/nature06501
| Summary | Full Text (HTML / PDF) |
letter
Macrophage migration inhibitory factor stimulates AMP-activated protein kinase in the ischaemic heart
Edward J. Miller et al.
Nature 451, 578–582
(31 January 2008); doi:10.1038/nature06504
| Summary | Full Text (HTML / PDF) |
letter
DBC1 is a negative regulator of SIRT1
Ja-Eun Kim, Junjie Chen & Zhenkun Lou
Nature 451, 583–586
(31 January 2008); doi:10.1038/nature06500
| Summary | Full Text (HTML / PDF) |
letter
Negative regulation of the deacetylase SIRT1 by DBC1
Wenhui Zhao, Jan-Philipp Kruse, Yi Tang, Sung Yun Jung, Jun Qin & Wei Gu
Nature 451, 587–590
(31 January 2008); doi:10.1038/nature06515
| Summary | Full Text (HTML / PDF) |
review
Membrane recognition by phospholipid-binding domains
Mark A. Lemmon
Nature Reviews Molecular Cell Biology 9, 99–111
(February 2008); doi:10.1038/nrm2328
| Summary | Full Text (HTML / PDF) |
review
Lipid signalling in disease
Matthias P. Wymann & Roger Schneiter
Nature Reviews Molecular Cell Biology 9, 162–176
(February 2008); doi:10.1038/nrm2335
| Summary | Full Text (HTML / PDF) |
article
'Tuning' of type I interferon-induced Jak–STAT1 signaling by calcium-dependent kinases in macrophages
Lu Wang et al.
Nature Immunology 9, 186–193
(February 2008); doi:10.1038/ni1548
| Summary | Full Text (HTML / PDF) |
article
Activated leukocyte cell adhesion molecule promotes leukocyte trafficking into the central nervous system
Romain Cayrol et al.
Nature Immunology 9, 137–145
(February 2008); doi:10.1038/ni1551
| Summary | Full Text (HTML / PDF) |
news and views
Lymphocyte transmigration in the brain: a new way of thinking
Boris P-L Lee & Beat A Imhof
Nature Immunology 9, 117–118
(February 2008); doi:10.1038/ni0208-117
| Full Text (HTML / PDF) |
review
FBW7 ubiquitin ligase: a tumour suppressor at the crossroads of cell division, growth and differentiation
Markus Welcker & Bruce E. Clurman
Nature Reviews Cancer 8, 83–93
(February 2008); doi:10.1038/nrc2290
| Summary | Full Text (HTML / PDF) |
article
Deficiency or inhibition of oxygen sensor Phd1 induces hypoxia tolerance by reprogramming basal metabolism
Julián Aragonés et al.
Nature Genetics 40, 170–180
(February 2008); doi:10.1038/ng.2007.62
| Summary | Full Text (HTML / PDF) |
news and views
Hypoxic reprogramming
Daniel P Kelly
Nature Genetics 40, 132–134
(February 2008); doi:10.1038/ng0208-132
| Full Text (HTML / PDF) |
article
Ephrin-B reverse signaling promotes structural and functional synaptic maturation in vivo
Byung Kook Lim, Naoto Matsuda & Mu-ming Poo
Nature Neuroscience 11, 160–169
(February 2008); doi:10.1038/nn2033
| Summary | Full Text (HTML / PDF) |
review
Derive and conquer: sourcing and differentiating stem cells for therapeutic applications
Irina Klimanskaya, Nadia Rosenthal & Robert Lanza
Nature Reviews Drug Discovery 7, 131–142
(February 2008); doi:10.1038/nrd2403
| Summary | Full Text (HTML / PDF) |
perspective
New surveyor tools for charting microbial metabolic maps
Rainer Breitling, Dennis Vitkup & Michael P. Barrett
Nature Reviews Microbiology 6, 156–161
(February 2008); doi:10.1038/nrmicro1797
| Summary | Full Text (HTML / PDF) |
brief communication
High-density mapping of single-molecule trajectories with photoactivated localization microscopy
Suliana Manley et al.
Nature Methods 5, 155–157
(February 2008); doi:10.1038/nmeth.1176
| Summary | Full Text (HTML / PDF) |
brief communication
Highly inclined thin illumination enables clear single-molecule imaging in cells
Makio Tokunaga, Naoko Imamoto & Kumiko Sakata-Sogawa
Nature Methods 5, 159–161
(February 2008); doi:10.1038/nmeth1171
| Summary | Full Text (HTML / PDF) |
news and views
How the sum of its parts gets greater than the whole
Mario Brameshuber & Gerhard J Schütz
Nature Methods 5, 133–134
(February 2008); doi:10.1038/nmeth0208-133
| Summary | Full Text (HTML / PDF) |
brief communication
Site selectivity of platinum anticancer therapeutics
Bin Wu, Peter Dröge & Curt A Davey
Nature Chemical Biology 4, 110–112
(February 2008); doi:10.1038/nchembio.2007.58
| Summary | Full Text (HTML / PDF) |
news and views
Worming our way to the fountain of youth
Peter John Roy
Nature Chemical Biology 4, 88–89
(February 2008); doi:10.1038/nchembio0208-88
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