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April 2008
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The Research Library categorizes, and provides access to, all recent signaling-related research published in the Nature Publishing Group journals. The selection is deliberately broad to facilitate access to all research impacting on the signaling community. Both primary research and review articles are included, as are 'News and Views' articles.
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article
Lateral presynaptic inhibition mediates gain control in an olfactory circuit
Shawn R. Olsen & Rachel I. Wilson
Nature 452, 956–960
(24 April 2008); doi:10.1038/nature06864
| Summary | Full Text (HTML / PDF) |
article
Crystal structures of DNA/RNA repair enzymes AlkB and ABH2 bound to dsDNA
Cai-Guang Yang et al.
Nature 452, 961–965
(24 April 2008); doi:10.1038/nature06889
| Summary | Full Text (HTML / PDF) |
letter
Insect olfactory receptors are heteromeric ligand-gated ion channels
Koji Sato et al.
Nature 452, 1002–1006
(24 April 2008); doi:10.1038/nature06850
| Summary | Full Text (HTML / PDF) |
letter
Drosophila odorant receptors are both ligand-gated and cyclic-nucleotide-activated cation channels
Dieter Wicher et al.
Nature 452, 1007–1011
(24 April 2008); doi:10.1038/nature06861
| Summary | Full Text (HTML / PDF) |
news and views
Neuroscience: Current views on odour receptors
Alexander Chesler & Stuart Firestein
Nature 452, 944
(24 April 2008); doi:10.1038/452944a
| Full Text (HTML / PDF) |
letter
A deadenylation negative feedback mechanism governs meiotic metaphase arrest
Eulàlia Belloc & Raúl Méndez
Nature 452, 1017–1021
(24 April 2008); doi:10.1038/nature06809
| Summary | Full Text (HTML / PDF) |
news and views
Gene transcription: Two worlds merged
David M. Lonard & Bert W. O'Malley
Nature 452, 946–947
(24 April 2008); doi:10.1038/452946a
| Full Text (HTML / PDF) |
letter
The NHL-domain protein Wech is crucial for the integrin-cytoskeleton link
Birgit Löer et al.
Nature Cell Biology 10, 422–428
(April 2008); doi:10.1038/ncb1704
| Summary | Full Text (HTML / PDF) |
letter
elipsa is an early determinant of ciliogenesis that links the IFT particle to membrane-associated small GTPase Rab8
Yoshihiro Omori et al.
Nature Cell Biology 10, 437–444
(April 2008); doi:10.1038/ncb1706
| Summary | Full Text (HTML / PDF) |
letter
Functional interaction between FOXO3a and ATM regulates DNA damage response
Wen-Bin Tsai, Young Min Chung, Yoko Takahashi, Zhaohui Xu & Mickey C.-T. Hu
Nature Cell Biology 10, 460–467
(April 2008); doi:10.1038/ncb1709
| Summary | Full Text (HTML / PDF) |
letter
A bistable Rb–E2F switch underlies the restriction point
Guang Yao, Tae Jun Lee, Seiichi Mori, Joseph R. Nevins & Lingchong You
Nature Cell Biology 10, 476–482
(April 2008); doi:10.1038/ncb1711
| Summary | Full Text (HTML / PDF) |
review
Tracking the ends: a dynamic protein network controls the fate of microtubule tips
Anna Akhmanova & Michel O. Steinmetz
Nature Reviews Molecular Cell Biology 9, 309–322
(April 2008); doi:10.1038/nrm2369
| Summary | Full Text (HTML / PDF) |
article
TRIM30α negatively regulates TLR-mediated NF-κB activation by targeting TAB2 and TAB3 for degradation
Mude Shi et al.
Nature Immunology 9, 369–377
(April 2008); doi:10.1038/ni1577
| Summary | Full Text (HTML / PDF) |
news and views
TRIM-ing down Tolls
Andrew G Bowie
Nature Immunology 9, 348–350
(April 2008); doi:10.1038/ni0408-348
| Full Text (HTML / PDF) |
article
Subversion of Toll-like receptor signaling by a unique family of bacterial Toll/interleukin-1 receptor domain-containing proteins
Christine Cirl et al.
Nature Medicine 14, 399–406
(April 2008); doi:10.1038/nm1734
| Summary | Full Text (HTML / PDF) |
news and views
Bacteria fight back against Toll-like receptors
Luke A J O'Neill
Nature Medicine 14, 370–372
(April 2008); doi:10.1038/nm0408-370
| Summary | Full Text (HTML / PDF) |
review
GATA1-related leukaemias
Ritsuko Shimizu, James Douglas Engel & Masayuki Yamamoto
Nature Reviews Cancer 8, 279–287
(April 2008); doi:10.1038/nrc2348
| Summary | Full Text (HTML / PDF) |
brief communication
A mutation of human cytochrome c enhances the intrinsic apoptotic pathway but causes only thrombocytopenia
Ian M Morison et al.
Nature Genetics 40, 387–389
(April 2008); doi:10.1038/ng.103
| Summary | Full Text (HTML / PDF) |
news and views
Re-examining the role of cytochrome c in cell death
Eric Solary, Fabrizio Giordanetto & Guido Kroemer
Nature Genetics 40, 379–380
(April 2008); doi:10.1038/ng0408-379
| Summary | Full Text (HTML / PDF) |
review
Quiet as a mouse: dissecting the molecular and genetic basis of hearing
Steve D. M. Brown, Rachel E. Hardisty-Hughes & Philomena Mburu
Nature Reviews Genetics 9, 277–290
(April 2008); doi:10.1038/nrg2309
| Summary | Full Text (HTML / PDF) |
article
TrkB kinase is required for recovery, but not loss, of cortical responses following monocular deprivation
Megumi Kaneko, Jessica L Hanover, Pamela M England & Michael P Stryker
Nature Neuroscience 11, 497–504
(April 2008); doi:10.1038/nn2068
| Summary | Full Text (HTML / PDF) |
brief communication
ALS-causing SOD1 mutants generate vascular changes prior to motor neuron degeneration
Zhihui Zhong et al.
Nature Neuroscience 11, 420–422
(April 2008); doi:10.1038/nn2073
| Summary | Full Text (HTML / PDF) |
article
MicroRNAs accurately identify cancer tissue origin
Nitzan Rosenfeld et al.
Nature Biotechnology 26, 462–469
(April 2008); doi:10.1038/nbt1392
| Summary | Full Text (HTML / PDF) |
news and views
Cancer biomarker profiling with microRNAs
Stefanie S Jeffrey
Nature Biotechnology 26, 400–401
(April 2008); doi:10.1038/nbt0408-400
| Summary | Full Text (HTML / PDF) |
review
Structural diversity of G protein-coupled receptors and significance for drug discovery
Malin C. Lagerström & Helgi B. Schiöth
Nature Reviews Drug Discovery 7, 339–357
(April 2008); doi:10.1038/nrd2518
| Summary | Full Text (HTML / PDF) |
article
Reciprocal regulation of the Ca2+ and H+ sensitivity in the SLO1 BK channel conferred by the RCK1 domain
Shangwei Hou, Rong Xu, Stefan H Heinemann & Toshinori Hoshi
Nature Structural & Molecular Biology 15, 403–410
(April 2008); doi:10.1038/nsmb.1398
| Summary | Full Text (HTML / PDF) |
brief communication
Crystal structures of two human vitronectin, urokinase and urokinase receptor complexes
Qing Huai et al.
Nature Structural & Molecular Biology 15, 422–423
(April 2008); doi:10.1038/nsmb.1404
| Summary | Full Text (HTML / PDF) |
brief communication
Genetic control of neuronal activity in mice conditionally expressing TRPV1
Benjamin R Arenkiel, Marguerita E Klein, Ian G Davison, Lawrence C Katz & Michael D Ehlers
Nature Methods 5, 299–302
(April 2008); doi:10.1038/nmeth.1190
| Summary | Full Text (HTML / PDF) |
news and views
Expanding the toolbox for remote control of neuronal circuits
Thomas Knöpfel
Nature Methods 5, 293–295
(April 2008); doi:10.1038/nmeth0408-293
| Summary | Full Text (HTML / PDF) |
article
Isolation of an active step I spliceosome and composition of its RNP core
Sergey Bessonov, Maria Anokhina, Cindy L. Will, Henning Urlaub & Reinhard Lührmann
Nature 452, 846–850
(17 April 2008); doi:10.1038/nature06842
| Summary | Full Text (HTML / PDF) |
letter
LNA-mediated microRNA silencing in non-human primates
Joacim Elmén et al.
Nature 452, 896–899
(17 April 2008); doi:10.1038/nature06783
| Summary | Full Text (HTML / PDF) |
letter
Integration of growth and specification in chick wing digit-patterning
Matthew Towers, Ruth Mahood, Yili Yin & Cheryll Tickle
Nature 452, 882–886
(17 April 2008); doi:10.1038/nature06718
| Summary | Full Text (HTML / PDF) |
letter
NAD synthase NMNAT acts as a chaperone to protect against neurodegeneration
R. Grace Zhai, Fan Zhang, P. Robin Hiesinger, Yu Cao, Claire M. Haueter & Hugo J. Bellen
Nature 452, 887–891
(17 April 2008); doi:10.1038/nature06721
| Summary | Full Text (HTML / PDF) |
letter
Retinotopic order in the absence of axon competition
Nathan J. Gosse, Linda M. Nevin & Herwig Baier
Nature 452, 892–895
(17 April 2008); doi:10.1038/nature06816
| Summary | Full Text (HTML / PDF) |
letter
Securin regulates entry into M-phase by modulating the stability of cyclin B
Petros Marangos & John Carroll
Nature Cell Biology 10, 445–451
(April 2008); doi:10.1038/ncb1707
| Summary | Full Text (HTML / PDF) |
news and views
Securin' M-phase entry
Mark J. Solomon & Janet L. Burton
Nature Cell Biology 10, 381–383
(April 2008); doi:10.1038/ncb0408-381
| Full Text (HTML / PDF) |
letter
Drosophila STAT is required for directly maintaining HP1 localization and heterochromatin stability
Song Shi et al.
Nature Cell Biology 10, 489–496
(April 2008); doi:10.1038/ncb1713
| Summary | Full Text (HTML / PDF) |
review
Exiting the Golgi complex
Maria Antonietta De Matteis & Alberto Luini
Nature Reviews Molecular Cell Biology 9, 273–284
(April 2008); doi:10.1038/nrm2378
| Summary | Full Text (HTML / PDF) |
review
How membrane proteins sense voltage
Francisco Bezanilla
Nature Reviews Molecular Cell Biology 9, 323–332
(April 2008); doi:10.1038/nrm2376
| Summary | Full Text (HTML / PDF) |
article
TNF activates an IRF1-dependent autocrine loop leading to sustained expression of chemokines and STAT1-dependent type I interferon–response genes
Anna Yarilina et al.
Nature Immunology 9, 378–387
(April 2008); doi:10.1038/ni1576
| Summary | Full Text (HTML / PDF) |
article
Autotaxin, an ectoenzyme that produces lysophosphatidic acid, promotes the entry of lymphocytes into secondary lymphoid organs
Hidenobu Kanda, Rebecca Newton, Russell Klein, Yuka Morita, Michael D Gunn & Steven D Rosen
Nature Immunology 9, 415–423
(April 2008); doi:10.1038/ni1573
| Summary | Full Text (HTML / PDF) |
news and views
A new player in lymphocyte homing
Dietmar Vestweber & Martin K Wild
Nature Immunology 9, 347–348
(April 2008); doi:10.1038/ni0408-347
| Full Text (HTML / PDF) |
review
Cis interactions of immunoreceptors with MHC and non-MHC ligands
Werner Held & Roy A. Mariuzza
Nature Reviews Immunology 8, 269–278
(April 2008); doi:10.1038/nri2278
| Summary | Full Text (HTML / PDF) |
review
The Cdk inhibitor p27 in human cancer: prognostic potential and relevance to anticancer therapy
Isabel M. Chu, Ludger Hengst & Joyce M. Slingerland
Nature Reviews Cancer 8, 253–267
(April 2008); doi:10.1038/nrc2347
| Summary | Full Text (HTML / PDF) |
article
THM1 negatively modulates mouse sonic hedgehog signal transduction and affects retrograde intraflagellar transport in cilia
Pamela V Tran et al.
Nature Genetics 40, 403–410
(April 2008); doi:10.1038/ng.105
| Summary | Full Text (HTML / PDF) |
article
LKB1 signaling in mesenchymal cells required for suppression of gastrointestinal polyposis
Pekka Katajisto et al.
Nature Genetics 40, 455–459
(April 2008); doi:10.1038/ng.98
| Summary | Full Text (HTML / PDF) |
article
Compartment-specific transcription factors orchestrate angiogenesis gradients in the embryonic brain
Anju Vasudevan, Jason E Long, James E Crandall, John L R Rubenstein & Pradeep G Bhide
Nature Neuroscience 11, 429–439
(April 2008); doi:10.1038/nn2074
| Summary | Full Text (HTML / PDF) |
perspective
A common neurobiology for pain and pleasure
Siri Leknes & Irene Tracey
Nature Reviews Neuroscience 9, 314–320
(April 2008); doi:10.1038/nrn2333
| Summary | Full Text (HTML / PDF) |
review
Targeting melanocortin receptors: an approach to treat weight disorders and sexual dysfunction
Jarl E. S. Wikberg & Felikss Mutulis
Nature Reviews Drug Discovery 7, 307–323
(April 2008); doi:10.1038/nrd2331
| Summary | Full Text (HTML / PDF) |
review
Cell-division inhibitors: new insights for future antibiotics
Rowena L. Lock & Elizabeth J. Harry
Nature Reviews Drug Discovery 7, 324–338
(April 2008); doi:10.1038/nrd2510
| Summary | Full Text (HTML / PDF) |
article
The retinitis pigmentosa 2 gene product is a GTPase-activating protein for Arf-like 3
Stefan Veltel, Raphael Gasper, Elke Eisenacher & Alfred Wittinghofer
Nature Structural & Molecular Biology 15, 373–380
(April 2008); doi:10.1038/nsmb.1396
| Summary | Full Text (HTML / PDF) |
article
Photochemical control of endogenous ion channels and cellular excitability
Doris L Fortin et al.
Nature Methods 5, 331–338
(April 2008); doi:10.1038/nmeth.1187
| Summary | Full Text (HTML / PDF) |
article
NFκB selectivity of estrogen receptor ligands revealed by comparative crystallographic analyses
Kendall W Nettles et al.
Nature Chemical Biology 4, 241–247
(April 2008); doi:10.1038/nchembio.76
| Summary | Full Text (HTML / PDF) |
news and views
Fast-tracking steroid receptor crystallization
Sylvie Mader
Nature Chemical Biology 4, 226–227
(April 2008); doi:10.1038/nchembio0408-226
| Full Text (HTML / PDF) |
article
Opposing effects of polyglutamine expansion on native protein complexes contribute to SCA1
Janghoo Lim et al.
Nature 452, 713–718
(10 April 2008); doi:10.1038/nature06731
| Summary | Full Text (HTML / PDF) |
news and views
Neurodegeneration: A question of balance
Leslie Michels Thompson
Nature 452, 707–708
(10 April 2008); doi:10.1038/452707a
| Full Text (HTML / PDF) |
article
Clathrin is a key regulator of basolateral polarity
Sylvie Deborde et al.
Nature 452, 719–723
(10 April 2008); doi:10.1038/nature06828
| Summary | Full Text (HTML / PDF) |
news and views
Cell biology: Porter and sorter
Michael G. Roth
Nature 452, 706–707
(10 April 2008); doi:10.1038/452706a
| Full Text (HTML / PDF) |
letter
A plant pathogen virulence factor inhibits the eukaryotic proteasome by a novel mechanism
Michael Groll et al.
Nature 452, 755–758
(10 April 2008); doi:10.1038/nature06782
| Summary | Full Text (HTML / PDF) |
letter
Endothelins are vascular-derived axonal guidance cues for developing sympathetic neurons
Takako Makita, Henry M. Sucov, Cheryl E. Gariepy, Masashi Yanagisawa & David D. Ginty
Nature 452, 759–763
(10 April 2008); doi:10.1038/nature06859
| Summary | Full Text (HTML / PDF) |
letter
Impaired TH17 cell differentiation in subjects with autosomal dominant hyper-IgE syndrome
Joshua D. Milner et al.
Nature 452, 773–776
(10 April 2008); doi:10.1038/nature06764
| Summary | Full Text (HTML / PDF) |
news and views Q&A
Cell biology: SUMO
Erik Meulmeester & Frauke Melchior
Nature 452, 709–711
(10 April 2008); doi:10.1038/452709a
| Full Text (HTML / PDF) |
letter
Phosphoregulation and depolymerization-driven movement of the Dam1 complex do not require ring formation
Daniel R. Gestaut et al.
Nature Cell Biology 10, 407–414
(April 2008); doi:10.1038/ncb1702
| Summary | Full Text (HTML / PDF) |
news and views
Dam1 complexes go it alone on disassembling microtubules
Melissa K. Gardner & David J. Odde
Nature Cell Biology 10, 379–381
(April 2008); doi:10.1038/ncb0408-379
| Full Text (HTML / PDF) |
letter
Lamin A-dependent misregulation of adult stem cells associated with accelerated ageing
Paola Scaffidi & Tom Misteli
Nature Cell Biology 10, 452–459
(April 2008); doi:10.1038/ncb1708
| Summary | Full Text (HTML / PDF) |
review
Regulation of DNA repair throughout the cell cycle
Dana Branzei & Marco Foiani
Nature Reviews Molecular Cell Biology 9, 297–308
(April 2008); doi:10.1038/nrm2351
| Summary | Full Text (HTML / PDF) |
article
TRAM couples endocytosis of Toll-like receptor 4 to the induction of interferon-β
Jonathan C Kagan, Tian Su, Tiffany Horng, Amy Chow, Shizuo Akira & Ruslan Medzhitov
Nature Immunology 9, 361–368
(April 2008); doi:10.1038/ni1569
| Summary | Full Text (HTML / PDF) |
news and views
Location, location, location: identifying the neighborhoods of LPS signaling
Colin Watts
Nature Immunology 9, 343–345
(April 2008); doi:10.1038/ni0408-343
| Full Text (HTML / PDF) |
letter
Robo4 stabilizes the vascular network by inhibiting pathologic angiogenesis and endothelial hyperpermeability
Christopher A Jones et al.
Nature Medicine 14, 448–453
(April 2008); doi:10.1038/nm1742
| Summary | Full Text (HTML / PDF) |
news and views
Robo4 counteracts VEGF signaling
Lisette M Acevedo, Sara M Weis & David A Cheresh
Nature Medicine 14, 372–373
(April 2008); doi:10.1038/nm0408-372
| Full Text (HTML / PDF) |
perspective
Lessons from multidisciplinary translational trials on anti-angiogenic therapy of cancer
Rakesh K. Jain
Nature Reviews Cancer 8, 309–316
(April 2008); doi:10.1038/nrc2346
| Summary | Full Text (HTML / PDF) |
letter
Newly identified prion linked to the chromatin-remodeling factor Swi1 in Saccharomyces cerevisiae
Zhiqiang Du, Kyung-Won Park, Haijing Yu, Qing Fan & Liming Li
Nature Genetics 40, 460–465
(April 2008); doi:10.1038/ng.112
| Summary | Full Text (HTML / PDF) |
article
Plexin-A2 and its ligand, Sema6A, control nucleus–centrosome coupling in migrating granule cells
Julie Renaud et al.
Nature Neuroscience 11, 440–449
(April 2008); doi:10.1038/nn2064
| Summary | Full Text (HTML / PDF) |
article
Motor protein-dependent transport of AMPA receptors into spines during long-term potentiation
Susana S Correia et al.
Nature Neuroscience 11, 457–466
(April 2008); doi:10.1038/nn2063
| Summary | Full Text (HTML / PDF) |
review
High-throughput electrophysiology: an emerging paradigm for ion-channel screening and physiology
John Dunlop, Mark Bowlby, Ravikumar Peri, Dmytro Vasilyev & Robert Arias
Nature Reviews Drug Discovery 7, 358–368
(April 2008); doi:10.1038/nrd2552
| Summary | Full Text (HTML / PDF) |
article
GW182 interaction with Argonaute is essential for miRNA-mediated translational repression and mRNA decay
Ana Eulalio, Eric Huntzinger & Elisa Izaurralde
Nature Structural & Molecular Biology 15, 346–353
(April 2008); doi:10.1038/nsmb.1405
| Summary | Full Text (HTML / PDF) |
news and views
Think you know how miRNAs work? Think again.
Joel D Richter
Nature Structural & Molecular Biology 15, 334–336
(April 2008); doi:10.1038/nsmb0408-334
| Full Text (HTML / PDF) |
review
The TORrid affairs of viruses: effects of mammalian DNA viruses on the PI3K–Akt–mTOR signalling pathway
Nicholas J. Buchkovich, Yongjun Yu, Carisa A. Zampieri & James C. Alwine
Nature Reviews Microbiology 6, 266–275
(April 2008); doi:10.1038/nrmicro1855
| Summary | Full Text (HTML / PDF) |
brief communication
A quantitative analysis software tool for mass spectrometry-based proteomics
Sung Kyu Park, John D Venable, Tao Xu & John R Yates III
Nature Methods 5, 319–322
(April 2008); doi:10.1038/nmeth.1195
| Summary | Full Text (HTML / PDF) |
article
Sequence- and target-independent angiogenesis suppression by siRNA via TLR3
Mark E. Kleinman et al.
Nature 452, 591–597
(3 April 2008); doi:10.1038/nature06765
| Summary | Full Text (HTML / PDF) |
news and views
RNA interference: Generic block on angiogenesis
Raghu Kalluri & Keizo Kanasaki
Nature 452, 543–545
(3 April 2008); doi:10.1038/452543a
| Full Text (HTML / PDF) |
article
A nuclear receptor-like pathway regulating multidrug resistance in fungi
Jitendra K. Thakur et al.
Nature 452, 604–609
(3 April 2008); doi:10.1038/nature06836
| Summary | Full Text (HTML / PDF) |
news and views
Drug resistance: The fight against fungi
André Goffeau
Nature 452, 541–542
(3 April 2008); doi:10.1038/452541a
| Full Text (HTML / PDF) |
letter
Tumour maintenance is mediated by eNOS
Kian-Huat Lim, Brooke B. Ancrile, David F. Kashatus & Christopher M. Counter
Nature 452, 646–649
(3 April 2008); doi:10.1038/nature06778
| Summary | Full Text (HTML / PDF) |
letter
Cutaneous cancer stem cell maintenance is dependent on β-catenin signalling
Ilaria Malanchi et al.
Nature 452, 650–653
(3 April 2008); doi:10.1038/nature06835
| Summary | Full Text (HTML / PDF) |
letter
Dendritic cell PAR1–S1P3 signalling couples coagulation and inflammation
Frank Niessen et al.
Nature 452, 654–658
(3 April 2008); doi:10.1038/nature06663
| Summary | Full Text (HTML / PDF) |
review
The cancer biomarker problem
Charles L. Sawyers
Nature 452, 548–552
(3 April 2008); doi:10.1038/nature06913
| Summary | Full Text (HTML / PDF) |
review
Translating insights from the cancer genome into clinical practice
Lynda Chin & Joe W. Gray
Nature 452, 553–552
(3 April 2008); doi:10.1038/nature06914
| Summary | Full Text (HTML / PDF) |
review
Enabling personalized cancer medicine through analysis of gene-expression patterns
Laura J. van't Veer & René Bernards
Nature 452, 564–570
(3 April 2008); doi:10.1038/nature06915
| Summary | Full Text (HTML / PDF) |
review
Mining the plasma proteome for cancer biomarkers
Samir M. Hanash, Sharon J. Pitteri & Vitor M. Faca
Nature 452, 571–579
(3 April 2008); doi:10.1038/nature06916
| Summary | Full Text (HTML / PDF) |
review
Imaging in the era of molecular oncology
Ralph Weissleder & Mikael J. Pittet
Nature 452, 580–589
(3 April 2008); doi:10.1038/nature06917
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article
Inn1 couples contraction of the actomyosin ring to membrane ingression during cytokinesis in budding yeast
Alberto Sanchez-Diaz et al.
Nature Cell Biology 10, 395–406
(April 2008); doi:10.1038/ncb1701
| Summary | Full Text (HTML / PDF) |
letter
Drosophila short neuropeptide F signalling regulates growth by ERK-mediated insulin signalling
Kyu-Sun Lee et al.
Nature Cell Biology 10, 468–475
(April 2008); doi:10.1038/ncb1710
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review
The role of oxygen availability in embryonic development and stem cell function
M. Celeste Simon & Brian Keith
Nature Reviews Molecular Cell Biology 9, 285–296
(April 2008); doi:10.1038/nrm2354
| Summary | Full Text (HTML / PDF) |
article
Regulation of T cell survival through coronin-1-mediated generation of inositol-1,4,5-trisphosphate and calcium mobilization after T cell receptor triggering
Philipp Mueller et al.
Nature Immunology 9, 424–431
(April 2008); doi:10.1038/ni1570
| Summary | Full Text (HTML / PDF) |
article
Dual functions for the endoplasmic reticulum calcium sensors STIM1 and STIM2 in T cell activation and tolerance
Masatsugu Oh-hora et al.
Nature Immunology 9, 432–443
(April 2008); doi:10.1038/ni1574
| Summary | Full Text (HTML / PDF) |
review
How dying cells alert the immune system to danger
Hajime Kono & Kenneth L. Rock
Nature Reviews Immunology 8, 279–289
(April 2008); doi:10.1038/nri2215
| Summary | Full Text (HTML / PDF) |
letter
Interferon-γ is a therapeutic target molecule for prevention of postoperative adhesion formation
Hisashi Kosaka, Tomohiro Yoshimoto, Takayuki Yoshimoto, Jiro Fujimoto & Kenji Nakanishi
Nature Medicine 14, 437–441
(April 2008); doi:10.1038/nm1733
| Summary | Full Text (HTML / PDF) |
brief communication
Evolutionary plasticity of genetic interaction networks
Julia Tischler, Ben Lehner & Andrew G Fraser
Nature Genetics 40, 390–391
(April 2008); doi:10.1038/ng.114
| Summary | Full Text (HTML / PDF) |
article
Synaptic NMDA receptor activity boosts intrinsic antioxidant defenses
Sofia Papadia et al.
Nature Neuroscience 11, 476–487
(April 2008); doi:10.1038/nn2071
| Summary | Full Text (HTML / PDF) |
news and views
NMDA receptor activity regulates transcription of antioxidant pathways
Stuart A Lipton
Nature Neuroscience 11, 381–382
(April 2008); doi:10.1038/nn0408-381
| Full Text (HTML / PDF) |
review
Targeting melanocortin receptors: an approach to treat weight disorders and sexual dysfunction
Jarl E. S. Wikberg & Felikss Mutulis
Nature Reviews Drug Discovery 7, 307–323
(April 2008); doi:10.1038/nrd2331
| Summary | Full Text (HTML / PDF) |
article
Pore-opening mechanism of the nicotinic acetylcholine receptor evinced by proton transfer
Gisela D Cymes & Claudio Grosman
Nature Structural & Molecular Biology 15, 389–396
(April 2008); doi:10.1038/nsmb.1407
| Summary | Full Text (HTML / PDF) |
article
Direct measurement of protein dynamics inside cells using a rationally designed photoconvertible protein
Tomoki Matsuda, Atsushi Miyawaki & Takeharu Nagai
Nature Methods 5, 339–345
(April 2008); doi:10.1038/nmeth.1193
| Summary | Full Text (HTML / PDF) |
article
Identification of small molecules rescuing fragile X syndrome phenotypes in Drosophila
Shuang Chang, Steven M Bray, Zigang Li, Daniela C Zarnescu, Chuan He, Peng Jin & Stephen T Warren
Nature Chemical Biology 4, 256–263
(April 2008); doi:10.1038/nchembio.78
| Summary | Full Text (HTML / PDF) |
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