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The Research Library categorizes, and provides access to, all recent signaling-related research published in the Nature Publishing Group journals. The selection is deliberately broad to facilitate access to all research impacting on the signaling community. Both primary research and review articles are included, as are 'News and Views' articles.
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article
Misfolded proteins partition between two distinct quality control compartments
Daniel Kaganovich, Ron Kopito & Judith Frydman
Nature 454, 1088–1095
(28 August 2008); doi:10.1038/nature07195
| Summary | Full Text (HTML / PDF) |
letter
A blend of small molecules regulates both mating and development in Caenorhabditis elegans
Jagan Srinivasan et al.
Nature 454, 1115–1118
(28 August 2008); doi:10.1038/nature07168
| Summary | Full Text (HTML / PDF) |
letter
Metabolic gene regulation in a dynamically changing environment
Matthew R. Bennett et al.
Nature 454, 1119–1122
(28 August 2008); doi:10.1038/nature07211
| Summary | Full Text (HTML / PDF) |
news and views
Systems biology: Reverse engineering the cell
Nicholas T. Ingolia & Jonathan S. Weissman
Nature 454, 1059–1062
(28 August 2008); doi:10.1038/4541059a
| Full Text (HTML / PDF) |
letter
Multipotent somatic stem cells contribute to the stem cell niche in the Drosophila testis
Justin Voog, Cecilia D’Alterio & D. Leanne Jones
Nature 454, 1132–1136
(28 August 2008); doi:10.1038/nature07173
| Summary | Full Text (HTML / PDF) |
letter
Mouse development with a single E2F activator
Shih-Yin Tsai et al.
Nature 454, 1137–1141
(28 August 2008); doi:10.1038/nature07066
| Summary | Full Text (HTML / PDF) |
letter
Cell-specific ATP7A transport sustains copper-dependent tyrosinase activity in melanosomes
Subba Rao Gangi Setty et al.
Nature 454, 1142–1146
(28 August 2008); doi:10.1038/nature07163
| Summary | Full Text (HTML / PDF) |
review
Puzzles, promises and a cure for ageing
Jan Vijg & Judith Campisi
Nature 454, 1065–1071
(28 August 2008); doi:10.1038/nature07216
| Summary | Full Text (HTML / PDF) |
article
Actin restricts FcεRI diffusion and facilitates antigen-induced receptor immobilization
Nicholas L. Andrews et al.
Nature Cell Biology 10, 955–963
(August 2008); doi:10.1038/ncb1755
| Summary | Full Text (HTML / PDF) |
letter
Modulation of intracellular trafficking regulates cell intercalation in the Drosophila trachea
Daniel D. Shaye, Jordi Casanova & Marta Llimargas
Nature Cell Biology 10, 964–970
(August 2008); doi:10.1038/ncb1756
| Summary | Full Text (HTML / PDF) |
review
Cancer as an overhealing wound: an old hypothesis revisited
Matthias Schäfer & Sabine Werner
Nature Reviews Molecular Cell Biology 9, 628–638
(August 2008); doi:10.1038/nrm2455
| Summary | Full Text (HTML / PDF) |
article
Superoxide dismutase 1 regulates caspase-1 and endotoxic shock
Felix Meissner, Kaaweh Molawi & Arturo Zychlinsky
Nature Immunology 9, 866–872
(August 2008); doi:10.1038/ni.1633
| Summary | Full Text (HTML / PDF) |
letter
Angiotensin receptor agonistic autoantibodies induce pre-eclampsia in pregnant mice
Cissy C Zhou et al.
Nature Medicine 14, 855–862
(August 2008); doi:10.1038/nm.1856
| Summary | Full Text (HTML / PDF) |
review
Modes of resistance to anti-angiogenic therapy
Gabriele Bergers & Douglas Hanahan
Nature Reviews Cancer 8, 592–603
(August 2008); doi:10.1038/nrc2442
| Summary | Full Text (HTML / PDF) |
letter
Critical function of Prdm14 for the establishment of the germ cell lineage in mice
Masashi Yamaji et al.
Nature Genetics 40, 1016–1022
(August 2008); doi:10.1038/ng.186
| Summary | Full Text (HTML / PDF) |
news and views
One PRDM is not enough for germ cell development
Elizabeth K Bikoff & Elizabeth J Robertson
Nature Genetics 40, 934–935
(August 2008); doi:10.1038/ng0808-934
| Full Text (HTML / PDF) |
review
The genetics of vertebrate myogenesis
Robert J. Bryson-Richardson & Peter D. Currie
Nature Reviews Genetics 9, 632–646
(August 2008); doi:10.1038/nrg2369
| Summary | Full Text (HTML / PDF) |
article
Gating the pore of P2X receptor channels
Mufeng Li, Tsg-Hui Chang, Shai D Silberberg & Kenton J Swartz
Nature Neuroscience 11, 883–887
(August 2008); doi:10.1038/nn.2151
| Summary | Full Text (HTML / PDF) |
perspective
How can we realize the promise of personalized antidepressant medicines?
Florian Holsboer
Nature Reviews Neuroscience 9, 638–646
(August 2008); doi:10.1038/nrn2453
| Summary | Full Text (HTML / PDF) |
commentary
Promoting coherent minimum reporting guidelines for biological and biomedical investigations: the MIBBI project
Chris F Taylor et al.
Nature Biotechnology 26, 889–896
(August 2008); doi:10.1038/nbt0808-889
| Summary | Full Text (HTML / PDF) |
review
Pseudoreceptor models in drug design: bridging ligand- and receptor-based virtual screening
Yusuf Tanrikulu & Gisbert Schneider
Nature Reviews Drug Discovery 7, 667–677
(August 2008); doi:10.1038/nrd2615
| Summary | Full Text (HTML / PDF) |
article
A conserved face of the Jagged/Serrate DSL domain is involved in Notch trans-activation and cis-inhibition
Jemima Cordle et al.
Nature Structural & Molecular Biology 15, 849–857
(August 2008); doi:10.1038/nsmb.1457
| Summary | Full Text (HTML / PDF) |
review
Mechanisms of microbial traversal of the blood–brain barrier
Kwang Sik Kim
Nature Reviews Microbiology 6, 625–634
(August 2008); doi:10.1038/nrmicro1952
| Summary | Full Text (HTML / PDF) |
article
Dynamic multiple-target tracing to probe spatiotemporal cartography of cell membranes
Arnauld Sergé, Nicolas Bertaux, Hervé Rigneault & Didier Marguet
Nature Methods 5, 687–694
(August 2008); doi:10.1038/nmeth.1233
| Summary | Full Text (HTML / PDF) |
article
PRDM16 controls a brown fat/skeletal muscle switch
Patrick Seale et al.
Nature 454, 961–967
(21 August 2008); doi:10.1038/nature07182
| Summary | Full Text (HTML / PDF) |
letter
New role of bone morphogenetic protein 7 in brown adipogenesis and energy expenditure
Yu-Hua Tseng et al.
Nature 454, 1000–1004
(21 August 2008); doi:10.1038/nature07221
| Summary | Full Text (HTML / PDF) |
news and views
Developmental biology: Neither fat nor flesh
Barbara Cannon & Jan Nedergaard
Nature 454, 947–948
(21 August 2008); doi:10.1038/454947a
| Full Text (HTML / PDF) |
letter
The pathogen protein EspFU hijacks actin polymerization using mimicry and multivalency
Nathan A. Sallee et al.
Nature 454, 1005–1008
(21 August 2008); doi:10.1038/nature07170
| Summary | Full Text (HTML / PDF) |
letter
Structural mechanism of WASP activation by the enterohaemorrhagic E. coli effector EspFU
Hui-Chun Cheng, Brian M. Skehan, Kenneth G. Campellone, John M. Leong & Michael K. Rosen
Nature 454, 1009–1013
(21 August 2008); doi:10.1038/nature07160
| Summary | Full Text (HTML / PDF) |
article
The regulated assembly of a PKCε complex controls the completion of cytokinesis
Adrian T. Saurin et al.
Nature Cell Biology 10, 891–901
(August 2008); doi:10.1038/ncb1749
| Summary | Full Text (HTML / PDF) |
article
The auxin influx carrier LAX3 promotes lateral root emergence
Kamal Swarup et al.
Nature Cell Biology 10, 946–954
(August 2008); doi:10.1038/ncb1754
| Summary | Full Text (HTML / PDF) |
review
Building the cell: design principles of cellular architecture
Susanne M. Rafelski & Wallace F. Marshall
Nature Reviews Molecular Cell Biology 9, 593–602
(August 2008); doi:10.1038/nrm2460
| Summary | Full Text (HTML / PDF) |
article
Differently phosphorylated forms of the cortactin homolog HS1 mediate distinct functions in natural killer cells
Boyd Butler, Diana H Kastendieck & John A Cooper
Nature Immunology 9, 887–897
(August 2008); doi:10.1038/ni.1630
| Summary | Full Text (HTML / PDF) |
news and views
Distinct functions for HS1 in chemosensory versus adhesive signaling
Peter Beemiller & Matthew F Krummel
Nature Immunology 9, 833–834
(August 2008); doi:10.1038/ni0808-833
| Full Text (HTML / PDF) |
review
The known unknowns of antigen processing and presentation
Jatin M. Vyas, Annemarthe G. Van der Veen & Hidde L. Ploegh
Nature Reviews Immunology 8, 607–618
(August 2008); doi:10.1038/nri2368
| Summary | Full Text (HTML / PDF) |
article
Hepatocyte-specific ablation of Foxa2 alters bile acid homeostasis and results in endoplasmic reticulum stress
Irina M Bochkis et al.
Nature Medicine 14, 828–836
(August 2008); doi:10.1038/nm.1853
| Summary | Full Text (HTML / PDF) |
review
The semaphorins: versatile regulators of tumour progression and tumour angiogenesis
Gera Neufeld & Ofra Kessler
Nature Reviews Cancer 8, 632–645
(August 2008); doi:10.1038/nrc2404
| Summary | Full Text (HTML / PDF) |
letter
Loss of Fat4 disrupts PCP signaling and oriented cell division and leads to cystic kidney disease
Sakura Saburi et al.
Nature Genetics 40, 1010–1015
(August 2008); doi:10.1038/ng.179
| Summary | Full Text (HTML / PDF) |
review
DNA polymerases and human disease
Lawrence A. Loeb & Raymond J. Monnat, Jr
Nature Reviews Genetics 9, 594–604
(August 2008); doi:10.1038/nrg2345
| Summary | Full Text (HTML / PDF) |
article
Light-sensitive neurons and channels mediate phototaxis in C. elegans
Alex Ward, Jie Liu, Zhaoyang Feng & X Z Shawn Xu
Nature Neuroscience 11, 916–922
(August 2008); doi:10.1038/nn.2155
| Summary | Full Text (HTML / PDF) |
brief communication
The stress hormone corticosterone conditions AMPAR surface trafficking and synaptic potentiation
Laurent Groc, Daniel Choquet & Francis Chaouloff
Nature Neuroscience 11, 868–870
(August 2008); doi:10.1038/nn.2150
| Summary | Full Text (HTML / PDF) |
perspective
Neutralizing antibodies to therapeutic enzymes: considerations for testing, prevention and treatment
Jinhai Wang et al.
Nature Biotechnology 26, 901–908
(August 2008); doi:10.1038/nbt.1484
| Summary | Full Text (HTML / PDF) |
article
The ClC-0 chloride channel is a 'broken' Cl−/H+ antiporter
Jirí Lísal & Merritt Maduke
Nature Structural & Molecular Biology 15, 805–810
(August 2008); doi:10.1038/nsmb.1466
| Summary | Full Text (HTML / PDF) |
news and views
The chloride channel's appendix
Joseph A Mindell
Nature Structural & Molecular Biology 15, 781–783
(August 2008); doi:10.1038/nsmb0808-781
| Full Text (HTML / PDF) |
article
The structure of CCT–Hsc70NBD suggests a mechanism for Hsp70 delivery of substrates to the chaperonin
Jorge Cuéllar et al.
Nature Structural & Molecular Biology 15, 858–864
(August 2008); doi:10.1038/nsmb.1464
| Summary | Full Text (HTML / PDF) |
article
A comprehensive strategy enabling high-resolution functional analysis of the yeast genome
David K Breslow et al.
Nature Methods 5, 711–718
(August 2008); doi:10.1038/nmeth.1234
| Summary | Full Text (HTML / PDF) |
article
A potent mechanism-inspired O-GlcNAcase inhibitor that blocks phosphorylation of tau in vivo
Scott A Yuzwa et al.
Nature Chemical Biology 4, 483–490
(August 2008); doi:10.1038/nchembio.96
| Summary | Full Text (HTML / PDF) |
news and views
Turning down tau phosphorylation
Peter M Fischer
Nature Chemical Biology 4, 448–449
(August 2008); doi:10.1038/nchembio0808-448
| Full Text (HTML / PDF) |
article
UCP2 mediates ghrelin’s action on NPY/AgRP neurons by lowering free radicals
Zane B. Andrews et al.
Nature 454, 846–851
(14 August 2008); doi:10.1038/nature07181
| Summary | Full Text (HTML / PDF) |
letter
Dynamic thiolation–thioesterase structure of a non-ribosomal peptide synthetase
Dominique P. Frueh et al.
Nature 454, 903–906
(14 August 2008); doi:10.1038/nature07162
| Summary | Full Text (HTML / PDF) |
letter
Structural basis for the selectivity of the external thioesterase of the surfactin synthetase
Alexander Koglin et al.
Nature 454, 907–911
(14 August 2008); doi:10.1038/nature07161
| Summary | Full Text (HTML / PDF) |
news and views
Biochemistry: Fit for an enzyme
Shiven Kapur & Chaitan Khosla
Nature 454, 832–833
(14 August 2008); doi:10.1038/454832a
| Full Text (HTML / PDF) |
article
EGFR signalling as a negative regulator of Notch1 gene transcription and function in proliferating keratinocytes and cancer
Vihren Kolev et al.
Nature Cell Biology 10, 902–911
(August 2008); doi:10.1038/ncb1750
| Summary | Full Text (HTML / PDF) |
letter
IQGAP3 regulates cell proliferation through the Ras/ERK signalling cascade
Hisashi Nojima et al.
Nature Cell Biology 10, 971–978
(August 2008); doi:10.1038/ncb1757
| Summary | Full Text (HTML / PDF) |
review
Shaping cups into phagosomes and macropinosomes
Joel A. Swanson
Nature Reviews Molecular Cell Biology 9, 639–649
(August 2008); doi:10.1038/nrm2447
| Summary | Full Text (HTML / PDF) |
perspective
Regulation of TNFR1 and CD95 signalling by receptor compartmentalization
Stefan Schütze, Vladimir Tchikov & Wulf Schneider-Brachert
Nature Reviews Molecular Cell Biology 9, 655–662
(August 2008); doi:10.1038/nrm2430
| Summary | Full Text (HTML / PDF) |
article
Nonmuscle myosin light-chain kinase mediates neutrophil transmigration in sepsis-induced lung inflammation by activating β2 integrins
Jingsong Xu et al.
Nature Immunology 9, 880–886
(August 2008); doi:10.1038/ni.1628
| Summary | Full Text (HTML / PDF) |
review
WNT signalling in the immune system: WNT is spreading its wings
Frank J. T. Staal, Tiago C. Luis & Machteld M. Tiemessen
Nature Reviews Immunology 8, 581–593
(August 2008); doi:10.1038/nri2360
| Summary | Full Text (HTML / PDF) |
letter
Reversal of learning deficits in a Tsc2+/− mouse model of tuberous sclerosis
Dan Ehninger et al.
Nature Medicine 14, 843–848
doi:10.1038/nm1788
| Summary | Full Text (HTML / PDF) |
letter
A tumor necrosis factor-α–mediated pathway promoting autosomal dominant polycystic kidney disease
Xiaogang Li et al.
Nature Medicine 14, 863–868
doi:10.1038/nm1783
| Summary | Full Text (HTML / PDF) |
review
Single-strand break repair and genetic disease
Keith W. Caldecott
Nature Reviews Genetics 9, 619–631
(August 2008); doi:10.1038/nrg2380
| Summary | Full Text (HTML / PDF) |
article
Cell type–specific regulation of DARPP-32 phosphorylation by psychostimulant and antipsychotic drugs
Helen S Bateup et al.
Nature Neuroscience 11, 932–939
(August 2008); doi:10.1038/nn.2153
| Summary | Full Text (HTML / PDF) |
article
PICK1 uncoupling from mGluR7a causes absence-like seizures
Federica Bertaso et al.
Nature Neuroscience 11, 940–948
(August 2008); doi:10.1038/nn.2142
| Summary | Full Text (HTML / PDF) |
article
Site-specific conjugation of a cytotoxic drug to an antibody improves the therapeutic index
Jagath R Junutula et al.
Nature Biotechnology 26, 925–932
doi:10.1038/nbt.1480
| Summary | Full Text (HTML / PDF) |
news and views
Antibody-drug conjugates ace the tolerability test
Nitin K Damle
Nature Biotechnology 26, 884–885
(August 2008); doi:10.1038/nbt0808-884
| Full Text (HTML / PDF) |
article
Phosphorylation of the RNA polymerase II C-terminal domain dictates transcription termination choice
Rajani Kanth Gudipati, Tommaso Villa, Jocelyne Boulay & Domenico Libri
Nature Structural & Molecular Biology 15, 786–794
doi:10.1038/nsmb.1460
| Summary | Full Text (HTML / PDF) |
article
The Nrd1–Nab3–Sen1 termination complex interacts with the Ser5-phosphorylated RNA polymerase II C-terminal domain
Lidia Vasiljeva, Minkyu Kim, Hannes Mutschler, Stephen Buratowski & Anton Meinhart
Nature Structural & Molecular Biology 15, 795–804
doi:10.1038/nsmb.1468
| Summary | Full Text (HTML / PDF) |
news and views
Terminating transcription in yeast: whether to be a 'nerd' or a 'rat'
Ana G Rondon, Hannah E Mischo & Nick J Proudfoot
Nature Structural & Molecular Biology 15, 775–776
(August 2008); doi:10.1038/nsmb0808-775
| Full Text (HTML / PDF) |
review
Towards environmental systems biology of Shewanella
James K. Fredrickson et al.
Nature Reviews Microbiology 6, 592–603
(August 2008); doi:10.1038/nrmicro1947
| Summary | Full Text (HTML / PDF) |
perspective
Engineering GPCR signaling pathways with RASSLs
Bruce R Conklin et al.
Nature Methods 5, 673–678
(August 2008); doi:10.1038/nmeth.1232
| Summary | Full Text (HTML / PDF) |
article
The DEAD-box helicase DDX3X is a critical component of the TANK-binding kinase 1-dependent innate immune response
Didier Soulat et al.
The EMBO Journal 27, 2135–2146
(August 2008); doi:10.1038/emboj.2008.126
| Summary | Full Text (HTML / PDF) |
article
Secreted transcription factor controls Mycobacterium tuberculosis virulence
Sridharan Raghavan, Paolo Manzanillo, Kaman Chan, Cole Dovey & Jeffery S. Cox
Nature 454, 717–721
(7 August 2008); doi:10.1038/nature07219
| Summary | Full Text (HTML / PDF) |
news and views
Tuberculosis: Shrewd survival strategy
Steven A. Porcelli
Nature 454, 702–703
(7 August 2008); doi:10.1038/454702a
| Full Text (HTML / PDF) |
article
On the nature of partial agonism in the nicotinic receptor superfamily
Remigijus Lape, David Colquhoun & Lucia G. Sivilotti
Nature 454, 722–727
(7 August 2008); doi:10.1038/nature07139
| Summary | Full Text (HTML / PDF) |
article
A mechanism for asymmetric segregation of age during yeast budding
Zhanna Shcheprova, Sandro Baldi, Stephanie Buvelot Frei, Gaston Gonnet & Yves Barral
Nature 454, 728–734
(7 August 2008); doi:10.1038/nature07212
| Summary | Full Text (HTML / PDF) |
news and views
Cell biology: A molecular age barrier
Matt Kaeberlein
Nature 454, 709–710
(7 August 2008); doi:10.1038/454709a
| Full Text (HTML / PDF) |
letter
cAMP signalling in mushroom bodies modulates temperature preference behaviour in Drosophila
Sung-Tae Hong et al.
Nature 454, 771–775
(7 August 2008); doi:10.1038/nature07090
| Summary | Full Text (HTML / PDF) |
letter
Essential roles of PI(3)K–p110β in cell growth, metabolism and tumorigenesis
Shidong Jia et al.
Nature 454, 776–779
(7 August 2008); doi:10.1038/nature07091
| Summary | Full Text (HTML / PDF) |
letter
Crystal structure of the neurotrophin-3 and p75NTR symmetrical complex
Yong Gong, Peng Cao, Hong-jun Yu & Tao Jiang
Nature 454, 789–793
(7 August 2008); doi:10.1038/nature07089
| Summary | Full Text (HTML / PDF) |
article
A traffic-activated Golgi-based signalling circuit coordinates the secretory pathway
Teodoro Pulvirenti et al.
Nature Cell Biology 10, 912–922
(August 2008); doi:10.1038/ncb1751
| Summary | Full Text (HTML / PDF) |
news and views
Golgi gets wired up
Lennart Asp & Tommy Nilsson
Nature Cell Biology 10, 885–887
(August 2008); doi:10.1038/ncb0808-885
| Full Text (HTML / PDF) |
review
Nectins and nectin-like molecules: roles in contact inhibition of cell movement and proliferation
Yoshimi Takai, Jun Miyoshi, Wataru Ikeda & Hisakazu Ogita
Nature Reviews Molecular Cell Biology 9, 603–615
(August 2008); doi:10.1038/nrm2457
| Summary | Full Text (HTML / PDF) |
article
Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization
Veit Hornung et al.
Nature Immunology 9, 847–856
(August 2008); doi:10.1038/ni.1631
| Summary | Full Text (HTML / PDF) |
article
The NALP3 inflammasome is involved in the innate immune response to amyloid-β
Annett Halle et al.
Nature Immunology 9, 857–865
(August 2008); doi:10.1038/ni.1636
| Summary | Full Text (HTML / PDF) |
news and views
NLRs and the dangers of pollution and aging
Stephen B Willingham & Jenny P-Y Ting
Nature Immunology 9, 831–833
(August 2008); doi:10.1038/ni0808-831
| Full Text (HTML / PDF) |
review
Plasmacytoid dendritic cells: sensing nucleic acids in viral infection and autoimmune diseases
Michel Gilliet, Wei Cao & Yong-Jun Liu
Nature Reviews Immunology 8, 594–606
(August 2008); doi:10.1038/nri2358
| Summary | Full Text (HTML / PDF) |
review
Integrins in angiogenesis and lymphangiogenesis
Christie J. Avraamides, Barbara Garmy-Susini & Judith A. Varner
Nature Reviews Cancer 8, 604–617
(August 2008); doi:10.1038/nrc2353
| Summary | Full Text (HTML / PDF) |
review
Tuning gene expression to changing environments: from rapid responses to evolutionary adaptation
Luis López-Maury, Samuel Marguerat & Jürg Bähler
Nature Reviews Genetics 9, 583–593
(August 2008); doi:10.1038/nrg2398
| Summary | Full Text (HTML / PDF) |
brief communication
Control of thermotactic behavior via coupling of a TRP channel to a phospholipase C signaling cascade
Young Kwon, Hye-Seok Shim, Xiaoyue Wang & Craig Montell
Nature Neuroscience 11, 871–873
(August 2008); doi:10.1038/nn.2170
| Summary | Full Text (HTML / PDF) |
article
A drug-inducible transgenic system for direct reprogramming of multiple somatic cell types
Marius Wernig et al.
Nature Biotechnology 26, 916–924
(August 2008); doi:10.1038/nbt1483
| Summary | Full Text (HTML / PDF) |
article
Synaptotagmin arrests the SNARE complex before triggering fast, efficient membrane fusion in response to Ca2+
Michael C Chicka, Enfu Hui, Huisheng Liu & Edwin R Chapman
Nature Structural & Molecular Biology 15, 827–835
(August 2008); doi:10.1038/nsmb.1463
| Summary | Full Text (HTML / PDF) |
brief communication
Molecular recognition of nitrated fatty acids by PPARγ
Yong Li et al.
Nature Structural & Molecular Biology 15, 865–867
(August 2008); doi:10.1038/nsmb.1447
| Summary | Full Text (HTML / PDF) |
article
Detection of heteromerization of more than two proteins by sequential BRET–FRET
Paulina Carriba et al.
Nature Methods 5, 727–733
(August 2008); doi:10.1038/nmeth.1229
| Summary | Full Text (HTML / PDF) |
perspective
Cooperativity in macromolecular assembly
James R Williamson
Nature Chemical Biology 4, 458–465
(August 2008); doi:10.1038/nchembio.102
| Summary | Full Text (HTML / PDF) |
letter
An Fgf/Gremlin inhibitory feedback loop triggers termination of limb bud outgrowth
Jamie M. Verheyden & Xin Sun
Nature 454, 638–641
(31 July 2008); doi:10.1038/nature07085
| Summary | Full Text (HTML / PDF) |
letter
Pluripotent stem cells induced from adult neural stem cells by reprogramming with two factors
Jeong Beom Kim et al.
Nature 454, 646–650
(31 July 2008); doi:10.1038/nature07061
| Summary | Full Text (HTML / PDF) |
letter
The behaviour of Drosophila adult hindgut stem cells is controlled by Wnt and Hh signalling
Shigeo Takashima, Marianna Mkrtchyan, Amelia Younossi-Hartenstein, John R. Merriam & Volker Hartenstein
Nature 454, 651–655
(31 July 2008); doi:10.1038/nature07156
| Summary | Full Text (HTML / PDF) |
news and views
Developmental biology: Our fly cousins' gut
Chrysoula Pitsouli & Norbert Perrimon
Nature 454, 592–593
(31 July 2008); doi:10.1038/454592a
| Full Text (HTML / PDF) |
letter
Blocking VEGFR-3 suppresses angiogenic sprouting and vascular network formation
Tuomas Tammela et al.
Nature 454, 656–660
(31 July 2008); doi:10.1038/nature07083
| Summary | Full Text (HTML / PDF) |
article
Regulation of TORC1 by Rag GTPases in nutrient response
Eunjung Kim, Pankuri Goraksha-Hicks, Li Li, Thomas P. Neufeld & Kun-Liang Guan
Nature Cell Biology 10, 935–945
(August 2008); doi:10.1038/ncb1753
| Summary | Full Text (HTML / PDF) |
news and views
Nutrient sensing: TOR's Ragtime
Alfred J. Meijer & Patrice Codogno
Nature Cell Biology 10, 881–883
(August 2008); doi:10.1038/ncb0808-881
| Full Text (HTML / PDF) |
letter
EphrinB1 controls cell–cell junctions through the Par polarity complex
Hyun-Shik Lee, Tagvor G. Nishanian, Kathleen Mood, Yong-Sik Bong & Ira O. Daar
Nature Cell Biology 10, 979–986
(August 2008); doi:10.1038/ncb1758
| Summary | Full Text (HTML / PDF) |
review
ATR: an essential regulator of genome integrity
Karlene A. Cimprich & David Cortez
Nature Reviews Molecular Cell Biology 9, 616–627
(August 2008); doi:10.1038/nrm2450
| Summary | Full Text (HTML / PDF) |
article
An essential function for β-arrestin 2 in the inhibitory signaling of natural killer cells
Ming-Can Yu et al.
Nature Immunology 9, 898–907
(August 2008); doi:10.1038/ni.1635
| Summary | Full Text (HTML / PDF) |
news and views
Arrestin NK cell cytotoxicity
Yenan T Bryceson & Hans-Gustaf Ljunggren
Nature Immunology 9, 835–836
(August 2008); doi:10.1038/ni0808-835
| Full Text (HTML / PDF) |
progress
New roles for TIM family members in immune regulation
Vijay K. Kuchroo, Valerie Dardalhon, Sheng Xiao & Ana C. Anderson
Nature Reviews Immunology 8, 577–580
(August 2008); doi:10.1038/nri2366
| Summary | Full Text (HTML / PDF) |
review
VEGF-targeted therapy: mechanisms of anti-tumour activity
Lee M. Ellis & Daniel J. Hicklin
Nature Reviews Cancer 8, 579–591
(August 2008); doi:10.1038/nrc2403
| Summary | Full Text (HTML / PDF) |
letter
Gain-of-function mutations in TRPV4 cause autosomal dominant brachyolmia
Matthew J Rock et al.
Nature Genetics 40, 999–1003
(August 2008); doi:10.1038/ng.166
| Summary | Full Text (HTML / PDF) |
article
Oxygen levels affect axon guidance and neuronal migration in Caenorhabditis elegans
Roger Pocock & Oliver Hobert
Nature Neuroscience 11, 894–900
(August 2008); doi:10.1038/nn.2152
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news and views
Fresh air is good for nerves: hypoxia disturbs axon guidance
Chun-Liang Pan & Gian Garriga
Nature Neuroscience 11, 859–861
(August 2008); doi:10.1038/nn0808-859
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review
Targeting bile-acid signalling for metabolic diseases
Charles Thomas, Roberto Pellicciari, Mark Pruzanski, Johan Auwerx & Kristina Schoonjans
Nature Reviews Drug Discovery 7, 678–693
(August 2008); doi:10.1038/nrd2619
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article
Robust single-particle tracking in live-cell time-lapse sequences
Khuloud Jaqaman et al.
Nature Methods 5, 695–702
(August 2008); doi:10.1038/nmeth.1237
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Single-particle tracking: connecting the dots
Michael J Saxton
Nature Methods 5, 671–672
(August 2008); doi:10.1038/nmeth0808-671
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article
An integrated platform of genomic assays reveals small-molecule bioactivities
Shawn Hoon et al.
Nature Chemical Biology 4, 498–506
(August 2008); doi:10.1038/nchembio.100
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