Research library: G-protein/GPCR signaling
2002: December
| November | October
| September | August
| July | June
| May | April
| March | February
| January
Other Years: 2003 | 2004 | 2005 | 2006 | 2007 | 2008
December
letters to nature
Glucose transporter recycling in response to insulin is facilitated by myosin Myo1c
Avirup Bose, Adilson Guilherme, Stacey I. Robida, Sarah M. C. Nicoloro, Qiong L. Zhou, Zhen Y. Jiang, Darcy P. Pomerleau and Michael P. Czech
Nature 420, 821–824
(19 December 2002); doi:10.1038/nature01246
| First Paragraph | Full Text (HTML / PDF) |
article
Defective CCR7 expression on dendritic cells contributes to the development of visceral leishmaniasis
Manabu Ato, Simona Stäger, Christian R. Engwerda and Paul M. Kaye
Nature Immunology 3, 1185–1191
(December 2002); doi:10.1038/ni861
| Abstract | Full Text (HTML/PDF) |
article
β cells are responsible for CXCR3-mediated T-cell infiltration in insulitis
Simona Frigerio, Tobias Junt, Bao Lu, Craig Gerard, Urs Zumsteg, Georg A. Holländer and Luca Piali
Nature Medicine 8, 1414–1420
(December 2002); doi:10.1038/nm792
| Abstract | Full Text (HTML/PDF) |
review article
New therapeutics that antagonize endothelin: promises and frustrations
Giuseppe Remuzzi , Norberto Perico and Ariela Benigni
Nature Reviews Drug Discovery 1, 986–1001
(December 2002); doi:10.1038/nrd962
| Summary | Full Text (HTML / PDF) |
letters to nature
Endocytosis-mediated downregulation of LIN-12/Notch upon Ras activation in Caenorhabditis elegans
Daniel D. Shaye and Iva Greenwald
Nature 420, 686–690
(12 December 2002); doi:10.1038/nature01234
| First Paragraph | Full Text (HTML / PDF) |
letters to nature
Signal-dependent regulation of splicing via phosphorylation of Sam68
Nathalie Matter, Peter Herrlich and Harald König
Nature 420, 691–695
(12 December 2002); doi:10.1038/nature01153
| First Paragraph | Full Text (HTML / PDF) |
review article
Rho GTPases in cell biology
Sandrine Etienne-Manneville and Alan Hall
Nature 420, 629–635
(12 December 2002); doi:10.1038/nature01148
| Summary | Full Text (HTML / PDF) |
article
ARF6-GTP recruits Nm23-H1 to facilitate dynamin-mediated endocytosis during adherens junctions disassembly
Felipe Palacios, Jill K. Schweitzer, Rita L. Boshans and Crislyn D'Souza-Schorey
Nature Cell Biology 4, 929–936
(December 2002); doi:10.1038/ncb881
| Abstract | Full Text (HTML/PDF) |
brief communication
The WRP component of the WAVE-1 complex attenuates Rac-mediated signalling
Scott H. Soderling, Kathleen L. Binns, Gary A. Wayman, Stephen M. Davee, Siew Hwa Ong, Tony Pawson and John D. Scott
Nature Cell Biology 4, 970–975
(December 2002); doi:10.1038/ncb886
| First Paragraph | Full Text (HTML/PDF) |
brief communication
Bicaudal-D regulates COPI-independent Golgi-ER transport by recruiting the dynein-dynactin motor complex
Theodoros Matanis, Anna Akhmanova, Phebe Wulf, Elaine Del Nery, Thomas Weide, Tatiana Stepanova, Niels Galjart, Frank Grosveld, Bruno Goud, Chris I. De Zeeuw, Angelika Barnekow and Casper C. Hoogenraad
Nature Cell Biology 4, 986–992
(December 2002); doi:10.1038/ncb891
| First Paragraph | Full Text (HTML/PDF) |
article
Superficial NK1-expressing neurons control spinal excitability through activation of descending pathways
Rie Suzuki, Sara Morcuende, Mark Webber, Stephen P. Hunt and Anthony H. Dickenson
Nature Neuroscience 5, 1319–1326
(December 2002); doi:10.1038/nn966
| Abstract | Full Text (HTML/PDF) |
November
brief communication
Membrane microviscosity regulates endothelial cell motility
Prabar K. Ghosh, Amit Vasanji, Gurunathan Murugesan, Steven J. Eppell, Linda M. Graham and Paul L. Fox
Nature Cell Biology 4, 894–900
(November 2002); doi:10.1038/ncb873
| First Paragraph | Full Text (HTML/PDF) |
original paper
Differential roles of Ras and Rap1 in growth factor-dependent activation of phospholipase Cε
Chunhua Song, Takaya Satoh, Hironori Edamatsu, Dongmei Wu, Makoto Tadano, Xianlong Gao and Tohru Kataoka
Oncogene 21, 8105–8113
(November 2002); doi:10.1038/sj.onc.1206003
| Abstract |
brief communication
Wound healing recapitulates morphogenesis in Drosophila embryos
William Wood, Antonio Jacinto, Richard Grose, Sarah Woolner, Jonathan Gale, Clive Wilson and Paul Martin
Nature Cell Biology 4, 907–912
(November 2002); doi:10.1038/ncb875
| First Paragraph | Full Text (HTML/PDF) |
news and views
Drosophila, actin and videotape — new insights in wound healing
Stéphane Noselli
Nature Cell Biology 4, E251
(November 2002); doi:10.1038/ncb1102-e251b
| Full Text (HTML/PDF) |
review article
The pathogenesis of pituitary tumours
Sylvia L. Asa and Shereen Ezzat
Nature Reviews Cancer 2, 836–849
(November 2002); doi:10.1038/nrc926
| Summary | Full Text (HTML / PDF) |
article
Social feeding in Caenorhabditis elegans is induced by neurons that detect aversive stimuli
Mario de Bono, David M. Tobin, M. Wayne Davis, Leon Avery and Cornelia I. Bargmann
Nature 419, 899–903
(31 October 2002); doi:10.1038/nature01169
| First Paragraph | Full Text (HTML / PDF) |
letters to nature
Antagonistic pathways in neurons exposed to body fluid regulate social feeding in Caenorhabditis elegans
Juliet C. Coates and Mario de Bono
Nature 419, 925–929
(31 October 2002); doi:10.1038/nature01170
| First Paragraph | Full Text (HTML / PDF) |
news and views
Neurobiology: Social eating for stress
Marla B. Sokolowski
Nature 419, 893–894
(31 October 2002); doi:10.1038/419893a
| Full Text (HTML / PDF) |
brief communication
A novel Epac-specific cAMP analogue demonstrates independent regulation of Rap1 and ERK
Jorrit M. Enserink, Anne E. Christensen, Johan de Rooij, Miranda van Triest, Frank Schwede, Hans Gottfried Genieser, Stein O. Dřskeland, Jonathan L. Blank and Johannes L. Bos
Nature Cell Biology 4, 901–906
(November 2002); doi:10.1038/ncb874
| First Paragraph | Full Text (HTML/PDF) |
news and views
Spotlight on receptor/transducer interaction
John Spudich
Nature Structural Biology 9, 797–799
(November 2002); doi:10.1038/nsb1102-797
| Full Text (HTML/PDF) |
October
review article
G-Protein-coupled receptor oligomerization and its potential for drug discovery
Susan R. George, Brian F. O'Dowd and Samuel P. Lee
Nature Reviews Drug Discovery 1, 808–820
(October 2002); doi:10.1038/nrd913
| Summary | Full Text (HTML/PDF) |
article
Pepducin-based intervention of thrombin-receptor signaling and systemic platelet activation
Lidija Covic, Meghna Misra, Jehangir Badar, Christopher Singh and Athan Kuliopulos
Nature Medicine 8, 1161–1165
(October 2002); doi:10.1038/nm760
| First Paragraph | Full Text (HTML/PDF) |
news and views
Attacked from within, blood thins
Wadie F. Bahou
Nature Medicine 8, 1082–1083
(October 2002); doi:10.1038/nm1002-1082
| Full Text (HTML/PDF) |
article
Evidence for two apoptotic pathways in light-induced retinal degeneration
Wenshan Hao, Andreas Wenzel, Martin S. Obin, Ching-Kang Chen, Elliott Brill, Nataliia V. Krasnoperova, Pamela Eversole-Cire, Yelena Kleyner, Allen Taylor, Melvin I. Simon, Christian Grimm, Charlotte E. Remé and Janis Lem
Nature Genetics 32, 254–260
(October 2002); doi:10.1038/ng984
| Abstract | Full Text (HTML/PDF) |
news and views
Blinded by the light
Samuel G. Jacobson and Roderick R. McInnes
Nature Genetics 32, 215–216
(October 2002); doi:10.1038/ng1002-215
| Full Text (HTML/PDF) |
letter
Mutations in Rab3a alter circadian period and homeostatic response to sleep loss in the mouse
David Kapfhamer, Otto Valladares, Yi Sun, Patrick M. Nolan, John J. Rux, Steven E. Arnold, Sigrid C. Veasey and Maja Bucan
Nature Genetics 32, 290–295
(October 2002); doi:10.1038/ng991
| First Paragraph | Full Text (HTML/PDF) |
letters to nature
Reaction path of protein farnesyltransferase at atomic resolution
Stephen B. Long, Patrick J. Casey and Lorena S. Beese
Nature 419, 645–650
(10 October 2002); doi:10.1038/nature00986
| First Paragraph | Full Text (HTML / PDF) |
letter
Mutant frizzled-4 disrupts retinal angiogenesis in familial exudative vitreoretinopathy
Johane Robitaille, Marcia L.E. MacDonald, Ajamete Kaykas, Laird C. Sheldahl, Jutta Zeisler, Marie-Pierre Dubé, Lin-Hua Zhang, Roshni R. Singaraja, Duane L. Guernsey, Binyou Zheng, Lee F. Siebert, Ann Hoskin-Mott, Michael T. Trese, Simon N. Pimstone, Barkur S. Shastry, Randall T. Moon, Michael R. Hayden, Y. Paul Goldberg and Mark E. Samuels
Nature Genetics 32, 326–330
(October 2002); doi:10.1038/ng957
| First Paragraph | Full Text (HTML/PDF) |
letters to nature
Molecular basis of transmembrane signalling by sensory rhodopsin II-transducer complex
Valentin I. Gordeliy, Jörg Labahn, Rouslan Moukhametzianov, Rouslan Efremov, Joachim Granzin, Ramona Schlesinger, Georg Büldt, Tudor Savopol, Axel J. Scheidig, Johann P. Klare and Martin Engelhard
Nature 419, 484–487
(03 October 2002); doi:10.1038/nature01109
| First Paragraph | Full Text (HTML / PDF) |
article
Genome-wide association study and mouse model identify interaction between RET and EDNRB pathways in Hirschsprung disease
Minerva M. Carrasquillo, Andrew S. McCallion, Erik G. Puffenberger, Carl S. Kashuk, Nassim Nouri and Aravinda Chakravarti
Nature Genetics 32, 237–244
(October 2002); doi:10.1038/ng998
| Abstract | Full Text (HTML/PDF) |
September
perspectives
Timeline: Cyclic nucleotide research — still expanding after half a century
Joseph A. Beavo and Laurence L. Brunton
Nature Reviews Molecular Cell Biology 3, 710–718
(September 2002); doi:10.1038/nrm911
| Summary | Full Text (HTML / PDF) |
article
Zizimin1, a novel Cdc42 activator, reveals a new GEF domain for Rho proteins
Nahum Meller, Mohammad Irani-Tehrani, William B. Kiosses, Miguel A. Del Pozo and Martin A. Schwartz
Nature Cell Biology 4, 639–647
(September 2002); doi:10.1038/ncb835
| Abstract | Full Text (HTML/PDF) |
article
Activation of Notch-1 signaling maintains the neoplastic phenotype in human Ras-transformed cells
Sanne Weijzen, Paola Rizzo, Mike Braid, Radhika Vaishnav, Suzanne M. Jonkheer, Andrei Zlobin, Barbara A. Osborne, Sridevi Gottipati, Jon C. Aster, William C. Hahn, Michael Rudolf, Kalliopi Siziopikou, W. Martin Kast and Lucio Miele
Nature Medicine 8, 979–986
(September 2002); doi:10.1038/nm754
| Abstract | Full Text (HTML/PDF) |
review article
Signalling: Seven-transmembrane receptors
Kristen L. Pierce, Richard T. Premont and Robert J. Lefkowitz
Nature Reviews Molecular Cell Biology 3, 639–650
(September 2002); doi:10.1038/nrm908
| Summary | Full Text (HTML / PDF) |
article
Parathyroid hormone-related peptide is a naturally occurring, protein kinase A-dependent angiogenesis inhibitor
Manjiri M. Bakre, Yuhong Zhu, Hong Yin, Doug W. Burton, Robert Terkeltaub, Leonard J. Deftos and Judith A. Varner
Nature Medicine 8, 995–1003
(September 2002); doi:10.1038/nm753
| Abstract | Full Text (HTML/PDF) |
article
Nerve growth cone guidance mediated by G protein-coupled receptors
Yang Xiang, Yan Li, Zhe Zhang, Kai Cui, Sheng Wang, Xiao-bing Yuan, Chien-ping Wu, Mu-ming Poo and Shumin Duan
Nature Neuroscience 5, 843–848
(September 2002); doi:10.1038/nn899
| Abstract | Full Text (HTML/PDF) |
August
brief communication
Tiam1 mediates Ras activation of Rac by a PI(3)K-independent mechanism
John M. Lambert, Que T. Lambert, Gary W. Reuther, Angeliki Malliri, David P. Siderovski, John Sondek, John G. Collard and Channing J. Der
Nature Cell Biology 4, 621–625
(August 2002); doi:10.1038/ncb833
| First Paragraph | Full Text (HTML/PDF) |
review article
Kinase- and phosphatase-anchoring proteins: harnessing the dynamic duo
Andrea L. Bauman and John D. Scott
Nature Cell Biology 4, E203
(August 2002); doi:10.1038/ncb0802-e203
| Abstract | Full Text (HTML/PDF) |
news and views
Two-shot cocktail: Adenosine, dopamine and a twist of bγ
R. Adron Harris and Richard A. Morrisett
Nature Medicine 8, 777–779
(August 2002); doi:10.1038/nm0802-777
| Full Text (HTML/PDF) |
review article
The use of constitutively active GPCRs in drug discovery and functional genomics
Derek T. Chalmers and Dominic P. Behan
Nature Reviews Drug Discovery 1, 599–608
(August 2002); doi:10.1038/nrd872
| Summary | Full Text (HTML / PDF) |
letters to nature
Patched acts catalytically to suppress the activity of Smoothened
J. Taipale, M. K. Cooper, T. Maiti and P. A. Beachy
Nature 418, 892–896
(22 August 2002); doi:10.1038/nature00989
| First Paragraph | Full Text (HTML / PDF) |
review article
Signal transduction and endocytosis: close encounters of many kinds
Alexander Sorkin and Mark von Zastrow
Nature Reviews Molecular Cell Biology 3, 600–614
(August 2002); doi:10.1038/nrm883
| Summary | Full Text (HTML / PDF) |
article
Antidepressant, anxiolytic and anorectic effects of a melanin-concentrating hormone-1 receptor antagonist
Beth Borowsky, Margaret M. Durkin, Kristine Ogozalek, Mohammad R. Marzabadi, John DeLeon, Rainer Heurich, Harvey Lichtblau, Zoya Shaposhnik, Irena Daniewska, Thomas P. Blackburn, Theresa A. Branchek, Christophe Gerald, Pierre J. Vaysse and Carlos Forray
Nature Medicine 8, 825–830
(August 2002); doi:10.1038/nm741
| Abstract | Full Text (HTML/PDF) |
news and views
Rats lighten up with MCH antagonist
Michael W. Schwartz and Richard W. Gelling
Nature Medicine 8, 779–781
(August 2002); doi:10.1038/nm0802-779
| Full Text (HTML/PDF) |
letters to nature
Mechanism of regulation of WAVE1-induced actin nucleation by Rac1 and Nck
Sharon Eden, Rajat Rohatgi, Alexandre V. Podtelejnikov, Matthias Mann and Marc W. Kirschner
Nature 418, 790–793
(15 August 2002); doi:10.1038/nature00859
| First Paragraph | Full Text (HTML / PDF) |
news and views
Cell motility: Braking WAVEs
Giles O. C. Cory and Anne J. Ridley
Nature 418, 732–733
(15 August 2002); doi:10.1038/418732a
| Full Text (HTML / PDF) |
letters to nature
Gut hormone PYY3-36 physiologically inhibits food intake
Rachel L. Batterham, Michael A. Cowley , Caroline J. Small, Herbert Herzog, Mark A. Cohen, Catherine L. Dakin, Alison M. Wren, Audrey E. Brynes, Malcolm J. Low, Mohammad A. Ghatei, Roger D. Cone and Stephen R. Bloom
Nature 418, 650–654
(8 August 2002); doi:10.1038/nature00887
| First Paragraph | Full Text (HTML / PDF) |
news and views
Obesity: Keeping hunger at bay
Michael W. Schwartz and Gregory J. Morton Many different hormones control our weight and appetite. The discovery of another hormone, which suppresses appetite for up to 12 hours, may lead to a better understanding of this complex control system.
Nature 418, 595–597
(8 August 2002); doi:10.1038/418595a
| Full Text (HTML / PDF) |
article
b-Arrestins regulate a Ral-GDS-Ral effector pathway that mediates cytoskeletal reorganization
Moshmi Bhattacharya, Pieter H. Anborgh, Andy V. Babwah, Lianne B. Dale, Tomas Dobransky, Jeffery L. Benovic, Ross D. Feldman, Joseph M. Verdi, R. Jane Rylett and Stephen S. G. Ferguson
Nature Cell Biology 4, 547–555
(August 2002); doi:10.1038/ncb821
| Abstract | Full Text (HTML/PDF) |
article
Unconventional Rac-GEF activity is mediated through the Dock180-ELMO complex
Enrico Brugnera, Lisa Haney, Cynthia Grimsley, Mingjian Lu, Scott F. Walk, Annie-Carole Tosello-Trampont, Ian G. Macara, Hiten Madhani, Gerald R. Fink and Kodimangalam S. Ravichandran
Nature Cell Biology 4, 574–582
(August 2002); doi:10.1038/ncb824
| Abstract | Full Text (HTML/PDF) |
news and views
GEF without a Dbl domain?
Vania M. M. Braga
Nature Cell Biology 4, E188
(August 2002); doi:10.1038/ncb0802-e188
| Full Text (HTML/PDF) |
July
letter to nature
Intracellular calcium stores regulate activity-dependent neuropeptide release from dendrites
Mike Ludwig, Nancy Sabatier, Philip M. Bull, Rainer Landgraf, Govindan Dayanithi and Gareth Leng
Nature 418, 85–89
(5th July 2002); doi:10.1038/nature00822
| First Paragraph | Full Text (HTML/PDF) |
news and views
Extra Rabs unsnarl a lipid traffic jam
Martin O. Bergo and Stephen G. Young
Nature Medicine 8, 662–664
(July 2002); doi:10.1038/nm0702-662
| Full Text (HTML/PDF) |
brief communication
Regulation of dendritic development by the ARF exchange factor ARNO
Delia J. Hernández-Deviez, James E. Casanova and Jean M. Wilson
Nature Neuroscience 5, 623–624
(July 2002); doi:10.1038/nn865
| First Paragraph | Full Text (HTML/PDF) |
June
article
ROCK and Dia have opposing effects on adherens junctions downstream of Rho
Erik Sahai and Christopher J. Marshall
Nature Cell Biology 4, 408–415
(June 2002); doi:10.1038/ncb796
| Abstract | Full Text (HTML/PDF) |
letter to nature
Na+/H+ exchanger regulatory factor 2 directs parathyroid hormone 1 receptor signalling
Matthew J. Mahon, Mark Donowitz, C. Chris Yun and Gino V. Segre
Nature 417, 858–861
(20 June 2002); doi:10.1038/nature00816
| First Paragraph | Full Text (HTML/PDF) |
letter to nature
Mice deficient in the Rac activator Tiam1 are resistant to Ras-induced skin tumours
Angeliki Malliri, Rob A. van der Kammen, Kristopher Clark, Maarten van der Valk, Frits Michiels and John G. Collard
Nature 417, 867–871
(20 June 2002); doi:10.1038/nature00848
| First Paragraph | Full Text (HTML/PDF) |
May
article
Prokineticin 2 transmits the behavioural circadian rhythm of the suprachiasmatic nucleus
Michelle Y. Cheng, Clayton M. Bullock, Chuanyu Li, Alex G. Lee, Jason C. Bermak, James Belluzzi, David R. Weaver, Frances M. Leslie and Qun-Yong Zhou
Nature 417, 405–410
(May 2002); doi:10.1038/417405a
| Summary | Full Text (HTML/PDF) |
news and views
Circadian rhythms: A gut feeling for time
Michael H. Hastings
Nature 417, 391–392
(May 2002); doi:10.1038/417391a
| Full Text (HTML/PDF) |
article
Cyclic AMP-dependent protein kinase phosphorylation facilitates GABAB receptor-effector coupling
Andrés Couve, Philip Thomas, Andrew R. Calver, Warren D. Hirst, Menelas N. Pangalos, Frank S. Walsh, Trevor G. Smart and Stephen J. Moss
Nature Neuroscience 5, 415–424
(May 2002); doi:10.1038/nn833
| Abstract | Full Text (HTML/PDF) |
review article
Integration of calcium and Ras signalling
Peter J. Cullen and Peter J. Lockyer
Nature Reviews Molecular Cell Biology 3, 339–348
(May 2002); doi:10.1038/nrm808
| Abstract | Full Text (HTML/PDF) |
letter
Structural determinants for GoLoco-induced inhibition of nucleotide release by Ga subunits
Randall J. Kimple, Michelle E. Kimple, Laurie Betts, John Sondek and David P. Siderovski
Nature 416, 878-881
(25 April 2002); doi:10.1038/416878a
| Abstract | Full Text (HTML/PDF) |
article
Ras signalling on the endoplasmic reticulum and the Golgi
Vi K. Chiu, Trever Bivona, Angela Hach, J. Bernard Sajous, Joseph Silletti, Heidi Wiener, Ronald L. Johnson II, Adrienne D. Cox and Mark R. Philips
Nature Cell Biology 4, 343–350
(May 2002); doi:10.1038/ncb783
| Abstract | Full Text (HTML/PDF) |
review article
NEW THERAPEUTICS THAT MODULATE CHEMOKINE NETWORKS
Matthias K. Schwarz and Timothy N. C. Wells
Nature Reviews Drug Discovery 1, 347–358
(May 2002); doi:10.1038/nrd795
| Abstract | Full Text (HTML/PDF) |
April
review article
REGULATED TRANSPORT OF THE GLUCOSE TRANSPORTER GLUT4
Nia J. Bryant, Roland Govers and David E. James
Nature Reviews Molecular Cell Biology 3, 267–277
(April 2002); doi:10.1038/nrm782
| Abstract | Full Text (HTML/PDF) |
news and views
Neighbourhood Watch for the cytoskeleton
Alison Schuldt
Nature Cell Biology 4, E71
(April 2002); doi:10.1038/ncb0402-e71
| Full Text (HTML/PDF) |
article
Nucleotide exchange factor GEF-H1 mediates cross-talk between microtubules and the actin cytoskeleton
Mira Krendel, Frank T. Zenke and Gary M. Bokoch
Nature Cell Biology 4, 294–301
(April 2002); doi:10.1038/ncb773
| Abstract | Full Text (HTML/PDF) |
news and views
How Rab proteins link motors to membranes
Bruno Goud
Nature Cell Biology 4, E77
(April 2002); doi:10.1038/ncb0402-e77
| Full Text (HTML/PDF) |
article
Identification of an organelle receptor for myosin-Va
Xufeng S. Wu, Kang Rao, Hong Zhang, Fei Wang, James R. Sellers, Lydia E. Matesic, Neal G. Copeland, Nancy A. Jenkins and John A. Hammer III
Nature Cell Biology 4, 271–278
(April 2002); doi:10.1038/ncb760
| Abstract | Full Text (HTML/PDF) |
brief communication
Myosin IXb is a single-headed minus-end-directed processive motor
Akira Inoue, Junya Saito, Reiko Ikebe and Mitsuo Ikebe
Nature Cell Biology 4, 302–306
(April 2002); doi:10.1038/ncb774
| First Paragraph | Full Text (HTML/PDF) |
letters to nature
SWAP-70 is a guanine-nucleotide-exchange factor that mediates signalling of membrane ruffling
Masahiro Shinohara, Yoh Terada, Akihiro Iwamatsu, Azusa Shinohara, Naoki Mochizuki, Maiko Higuchi, Yukiko Gotoh, Sayoko Ihara, Satoshi Nagata, Hiroshi Itoh, Yasuhisa Fukui and Rolf Jessberger
Nature 416, 759–763
(April 2002); doi:10.1038/416759a
| First Paragraph | Full Text (HTML/PDF) |
letters to nature
Structural determinants for GoLoco-induced inhibition of nucleotide release by Ga subunits
Randall J. Kimple, Michelle E. Kimple, Laurie Betts, John Sondek and David P. Siderovski
Nature 416, 878–881
(April 2002); doi:10.1038/416878a
| First Paragraph | Full Text (HTML/PDF) |
March
review article
REGULATORS OF G-PROTEIN SIGNALLING AS NEW CENTRAL NERVOUS SYSTEM DRUG TARGETS
Richard R. Neubig and David P. Siderovski
Nature Reviews Drug Discovery 1, 187–197
(March 2002); doi:10.1038/nrd747
| Abstract | Full Text (HTML/PDF) |
news and views
Neurobiology: The bitter-sweet taste of amino acids
Lesley Anson
Nature 416, 136
(February 2002); doi:10.1038/416136b
| Full Text (HTML/PDF) |
letters to nature
An amino-acid taste receptor
First Paragraph
Nature 416, 199–202
(March 2002); doi:10.1038/nature726
| First Paragraph | Full Text (HTML/PDF) |
February
review article
EFFICACY AT G-PROTEIN-COUPLED RECEPTORS
Terry Kenakin
Nature Reviews Drug Discovery 1, 103–110
(February 2002); doi:10.1038/nrd722
| Abstract | Full Text (HTML/PDF) |
review article
RHO-GTPASES AND CANCER
Erik Sahai and Christopher J. Marshall
Nature Reviews Cancer 2, 133–142
(February 2002); doi:10.1038/nrc725
| Abstract | Full Text (HTML/PDF) |
review article
CHEMOKINE RECEPTORS: MULTIFACETED THERAPEUTIC TARGETS
Amanda E. I. Proudfoot
Nature Reviews Immunology 2, 106–115
(February 2002); doi:10.1038/nri722
| Abstract | Full Text (HTML/PDF) |
news and views
'Rab'ing up endosomal membrane transport
Magda Deneka and Peter van der Sluijs
Nature Cell Biology 4, E33
(February 2002); doi:10.1038/ncb0202-e33
| Full Text (HTML/PDF) |
article
Divalent Rab effectors regulate the sub-compartmental organization and sorting of early endosomes
Stefano De Renzis, Birte Sönnichsen and Marino Zerial
Nature Cell Biology 4, 124–133
(February 2002); doi:10.1038/ncb744
| Abstract | Full Text (HTML/PDF) |
letters to nature
RanGAP mediates GTP hydrolysis without an arginine finger
Michael J. Seewald, Carolin Körner, Alfred Wittinghofer and Ingrid R. Vetter
Nature 415, 662–666
(February 2002); doi:10.1038/415662a
| First Paragraph | Full Text (HTML/PDF) |
January
news and views
Strabismus comes into focus
Jeffrey D. Axelrod
Nature Cell Biology 4, E6
(January 2002); doi:10.1038/ncb0102-e6
| Full Text (HTML/PDF) |
article
The planar cell-polarity gene stbm regulates cell behaviour and cell fate in vertebrate embryos
Maiyon Park and Randall T. Moon
Nature Cell Biology 4, 20–25
(January 2002); doi:10.1038/ncb716
| Abstract |
article
The exocyst is a Ral effector complex
Serge Moskalenko, Dale O. Henry, Carine Rosse, Gladys Mirey, Jacques H. Camonis and Michael A. White
Nature Cell Biology 4, 66–72
(January 2002); doi:10.1038/ncb728
| Abstract |
brief communication
The exocyst complex binds the small GTPase RalA to mediate filopodia formation
Kazuhiro Sugihara, Shiro Asano, Kenichi Tanaka, Akihiro Iwamatsu, Katsuya Okawa and Yasutaka Ohta
Nature Cell Biology 4, 73–78
(January 2002); doi:10.1038/ncb720
| First Paragraph |
letters to nature
Phospholipase Cγ1 is a physiological guanine nucleotide exchange factor for the nuclear GTPase PIKE
Keqiang Ye, Bahman Aghdasi, Hongbo R. Luo, John L. Moriarity, Frederick Y. Wu, Jenny J. Hong, K. Joseph Hurt, Sun Sik Bae, Pann-Ghill Suh and Solomon H. Snyder
Nature 415, 541–544
(January 2002); doi:10.1038/415541a
| First Paragraph |
letters to nature
Mechanism for the learning deficits in a mouse model of neurofibromatosis type 1
Rui M. Costa, Nikolai B. Federov, Jeff H. Kogan, Geoffrey G. Murphy, Joel Stern, Masuo Ohno, Raju Kucherlapati, Tyler Jacks and Alcino J. Silva
Nature 415, 526–530
(January 2002); doi:10.1038/nature711
| First Paragraph |
letters to nature
Stage-specific control of neuronal migration by somatostatin
Elina Yacubova and Hitoshi Komuro
Nature 415, 77–81
(January 2002); doi:10.1038/415077a
| First Paragraph |
insight
Seven-transmembrane-spanning receptors and heart function
Howard A. Rockman, Walter J. Koch and Robert J. Lefkowitz
Nature 415, 206–212
(January 2002); doi:10.1038/415206a
| Summary |
|
