letters to nature The transcription factor Ifh1 is a key regulator of yeast ribosomal protein genes
Joseph T. Wade, Daniel B. Hall and Kevin Struhl Nature432, 1054–1058
(23 December 2004); doi:10.1038/nature03175
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letters to nature Growth-regulated recruitment of the essential yeast ribosomal protein gene activator Ifh1
Stephan B. Schawalder, Mehdi Kabani, Isabelle Howald, Urmila Choudhury, Michel Werner and David Shore Nature432, 1058–1061
(23 December 2004); doi:10.1038/nature03200
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letter Rab27A-binding protein Slp2-a is required for peripheral melanosome distribution and elongated cell shape in melanocytes
Taruho S. Kuroda and Mitsunori Fukuda Nature Cell Biology6, 1195–1203
(December 2004); doi:10.1038/ncb1197
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article Structural basis for the assembly of a nuclear export complex
Yoshiyuki Matsuura and Murray Stewart Nature432, 872–877
(16 December 2004); doi:10.1038/nature03144
| Abstract | Full Text (HTML / PDF) |
news and views Cell biology: Popping out of the nucleus
André Hoelz and Günter Blobel Nature432, 815–816
(16 December 2004); doi:10.1038/432815a
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review article Viral hijacking of G-protein-coupled-receptor signalling networks
Akrit Sodhi, Silvia Montaner and J. Silvio Gutkind Nature Reviews Molecular Cell Biology5, 998–1012
(December 2004); doi:10.1038/nrm1529
| Abstract | Full Text (HTML / PDF) |
letters to nature Regulation of cellular response to oncogenic and oxidative stress by Seladin-1
Chaowei Wu, Irene Miloslavskaya, Silvia Demontis, Roberta Maestro and Konstantin Galaktionov Nature432, 640–645
(02 December 2004); doi:10.1038/nature03173
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November
review article Targeting Rab GTPases to distinct membrane compartments
Suzanne Pfeffer and Dikran Aivazian Nature Reviews Molecular Cell Biology5, 886–896
(November 2004); doi:10.1038/nrm1500
| Abstract | Full Text (HTML / PDF) |
letter The RAB25 small GTPase determines aggressiveness of ovarian and breast cancers
Kwai Wa Cheng, John P Lahad, Wen-lin Kuo, Anna Lapuk, Kyosuke Yamada, Nelly Auersperg, Jinsong Liu, Karen Smith-McCune, Karen H Lu, David Fishman, Joe W Gray and Gordon B Mills Nature Medicine10, 1251–1256
(November 2004); doi:10.1038/nm1125
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October
article Rolling blackout, a newly identified PIP2-DAG pathway lipase required for Drosophila phototransduction
Fu-De Huang, Heinrich J G Matthies, Sean D Speese, Mark A Smith and Kendal Broadie Nature Neuroscience7, 1070–1078
(October 2004); doi:10.1038/nn1313
| Abstract | Full Text (HTML/PDF) |
review article Bradykinin receptor ligands: therapeutic perspectives
François Marceau and Domenico Regoli Nature Reviews Drug Discovery3, 845–852
(October 2004); doi:10.1038/nrd1522
| Abstract | Full Text (HTML / PDF) |
article Mechanism of extrasynaptic dopamine signaling in Caenorhabditis elegans
Daniel L Chase, Judy S Pepper and Michael R Koelle Nature Neuroscience7, 1096–1103
(October 2004); doi:10.1038/nn1316
| Abstract | Full Text (HTML/PDF) |
news and views Dopamine: should I stay or should I go now?
Erik M Jorgensen Nature Neuroscience7, 1019–1021
(October 2004); doi:10.1038/nn1004-1019
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article Structural basis of Rab5-Rabaptin5 interaction in endocytosis
Guangyu Zhu, Peng Zhai, Jian Liu, Simon Terzyan, Guangpu Li and Xuejun C Zhang Nature Structural and Molecular Biology11, 975–983
(October 2004); doi:10.1038/nsmb832
| Abstract | Full Text (HTML/PDF) |
article In vitro selection and prediction of TIP47 protein-interaction interfaces
Alondra Schweizer Burguete, Pehr B Harbury and Suzanne R Pfeffer Nature Methods1, 55–60
(October 2004); doi:10.1038/nmeth702
| Abstract | Full Text (HTML/PDF) |
September
article RhoH is required to maintain the integrin LFA-1 in a nonadhesive state on lymphocytes
Lisa K Cherry, Xiaoyu Li, Pascale Schwab, Bing Lim and Lloyd B Klickstein Nature Immunology5, 961–967
(September 2004); doi:10.1038/ni1103
| Abstract | Full Text (HTML/PDF) |
review article T-cell trafficking in asthma: lipid mediators grease the way
Andrew D. Luster and Andrew M. Tager Nature Reviews Immunology4, 711–724
(September 2004); doi:10.1038/nri1438
| Abstract | Full Text (HTML / PDF) |
letter Loss of BBS proteins causes anosmia in humans and defects in olfactory cilia structure and function in the mouse
Heather M Kulaga, Carmen C Leitch, Erica R Eichers, Jose L Badano, Alysa Lesemann, Bethan E Hoskins, James R Lupski, Philip L Beales, Randall R Reed and Nicholas Katsanis Nature Genetics36, 994–998
(September 2004); doi:10.1038/ng1418
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article The sequential activity of the GTPases Rap1B and Cdc42 determines neuronal polarity
Jens C Schwamborn and Andreas W Püschel Nature Neuroscience7, 923–929
(September 2004); doi:10.1038/nn1295
| Abstract | Full Text (HTML/PDF) |
review article The endocannabinoid system and its therapeutic exploitation
Vincenzo Di Marzo, Maurizio Bifulco and Luciano De Petrocellis Nature Reviews Drug Discovery3, 771–784
(September 2004); doi:10.1038/nrd1495
| Abstract | Full Text (HTML / PDF) |
article Effects of G-protein mutations on skin color
Catherine D Van Raamsdonk, Karen R Fitch, Helmut Fuchs, Martin Hrabé de Angelis and Gregory S Barsh Nature Genetics36, 961–968
(September 2004); doi:10.1038/ng1412
| Abstract | Full Text (HTML/PDF) |
news and views The G-netics of dark skin
Ian J Jackson Nature Genetics36, 935–936
(September 2004); doi:10.1038/ng0904-935
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letters to nature Reading the Hedgehog morphogen gradient by measuring the ratio of bound to unbound Patched protein
Andreu Casali and Gary Struhl Nature431, 76–80
(02 September 2004); doi:10.1038/nature02835
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article EB1 and APC bind to mDia to stabilize microtubules downstream of Rho and promote cell migration
Ying Wen, Christina H. Eng, Jan Schmoranzer, Noemi Cabrera–Poch, Edward J. S. Morris, Michael Chen, Bradley J. Wallar, Arthur S. Alberts and Gregg G. Gundersen Nature Cell Biology6, 820–830
(September 2004); doi:10.1038/ncb1160
| Abstract | Full Text (HTML/PDF) |
article Germinal center dark and light zone organization is mediated by CXCR4 and CXCR5
Christopher D C Allen, K Mark Ansel, Caroline Low, Robin Lesley, Hirokazu Tamamura, Nobutaka Fujii and Jason G Cyster Nature Immunology5, 943–952
(September 2004); doi:10.1038/ni1100
| Abstract | Full Text (HTML/PDF) |
letter Mutations in a member of the Ras superfamily of small GTP–binding proteins causes Bardet–Biedl syndrome
Yanli Fan, Muneer A Esmail, Stephen J Ansley, Oliver E Blacque, Keith Boroevich, Alison J Ross, Susan J Moore, Jose L Badano, Helen May–Simera, Deanna S Compton, Jane S Green, Richard Alan Lewis, Mieke M van Haelst, Patrick S Parfrey, David L Baillie, Philip L Beales, Nicholas Katsanis, William S Davidson and Michel R Leroux Nature Genetics36, 989–993
(September 2004); doi:10.1038/ng1414
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August
article Closed state of both binding domains of homodimeric mGlu receptors is required for full activity
Julie Kniazeff, Anne-Sophie Bessis, Damien Maurel, Hervé Ansanay, Laurent Prézeau and Jean-Philippe Pin Nature Structural and Molecular Biology11, 706–713
(August 2004); doi:10.1038/nsmb794
| Abstract | Full Text (HTML/PDF) |
news and views Toward understanding GPCR dimers
Charles Parnot and Brian Kobilka Nature Structural and Molecular Biology11, 691–692
(August 2004); doi:10.1038/nsmb0804-691
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article PH domain of ELMO functions in trans to regulate Rac activation via Dock180
Mingjian Lu, Jason M Kinchen, Kent L Rossman, Cynthia Grimsley, Colin deBakker, Enrico Brugnera, Annie-Carole Tosello-Trampont, Lisa B Haney, Doris Klingele, John Sondek, Michael O Hengartner and Kodi S Ravichandran Nature Structural and Molecular Biology11, 756–762
(August 2004); doi:10.1038/nsmb800
| Abstract | Full Text (HTML/PDF) |
review article Chemotaxis: signalling the way forward
Peter J. M. Van Haastert and Peter N. Devreotes Nature Reviews Molecular Cell Biology5, 626–634
(August 2004); doi:10.1038/nrm1435
| Summary | Full Text (HTML / PDF) |
article Novel regulatory mechanisms for the Dbl family guanine nucleotide exchange factor Cool-2/-Pix
Qiyu Feng, Daniel Baird and Richard A Cerione The EMBO Journal Advance online publishing
(12 August 2004); doi:10.1038/sj.emboj.7600331
| Abstract | Full Text (HTML/PDF) |
article RabGEF1 is a negative regulator of mast cell activation and skin inflammation
See-Ying Tam, Mindy Tsai, John N Snouwaert, Janet Kalesnikoff, Didier Scherrer, Susumu Nakae, Devavani Chatterjea, Donna M Bouley and Stephen J Galli Nature Immunology5, 844–852
(August 2004); doi:10.1038/ni1093
| Abstract | Full Text (HTML/PDF) |
article The imprinted signaling protein XLαs is required for postnatal adaptation to feeding
Antonius Plagge, Emma Gordon, Wendy Dean, Romina Boiani, Saverio Cinti, Jo Peters and Gavin Kelsey Nature Genetics36, 818–826
(August 2004); doi:10.1038/ng1397
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letter A cis-acting control region is required exclusively for the tissue-specific imprinting of Gnas
Christine M Williamson, Simon T Ball, Wade T Nottingham, Judith A Skinner, Antonius Plagge, Martin D Turner, Nicola Powles, Tertius Hough, David Papworth, William D Fraser, Mark Maconochie and Jo Peters Nature Genetics36, 894–899
(August 2004); doi:10.1038/ng1398
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news and views Complex imprinting
Arthur L Beaudet Nature Genetics36, 793–795
(August 2004); doi:10.1038/ng0804-793
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July
article Ligand-induced rearrangement of the dimeric metabotropic glutamate receptor 1α
Michihiro Tateyama, Hideki Abe, Hiroyasu Nakata, Osamu Saito and Yoshihiro Kubo Nature Structural and Molecular Biology11, 637–642
(July 2004); doi:10.1038/nsmb770
| Abstract | Full Text (HTML/PDF) |
article Localization of Rac2 via the C terminus and aspartic acid 150 specifies superoxide generation, actin polarity and chemotaxis in neutrophils
Marie-Dominique Filippi, Chad E Harris, Jarek Meller, Yi Gu, Yi Zheng and David A Williams Nature Immunology5, 744–751
(July 2004); doi:10.1038/ni1081
| Abstract | Full Text (HTML/PDF) |
letter Spatiotemporal regulation of endothelin receptor-B by SOX10 in neural crest-derived enteric neuron precursors
Lei Zhu, Hyung-Ok Lee, ChaRandle S Jordan, V Ashley Cantrell, E Michelle Southard-Smith and Myung K Shin Nature Genetics36, 732–737
(July 2004); doi:10.1038/ng1371
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brief communication Inhibition of cyclooxygenase-2 potentiates retrograde endocannabinoid effects in hippocampus
Jimok Kim and Bradley E Alger Nature Neuroscience7, 697–698
(July 2004); doi:10.1038/nn1262
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article GRK2 is an endogenous protein inhibitor of the insulin signaling pathway for glucose transport stimulation
Isao Usui, Takeshi Imamura, Hiroaki Satoh, Jie Huang, Jennie L Babendure, Christopher J Hupfeld and Jerrold M Olefsky The EMBO Journal23, 2821–2829
(July 2004); doi:10.1038/sj.emboj.7600297
| Abstract | Full Text (HTML/PDF) |
article Initiation of neuropathic pain requires lysophosphatidic acid receptor signaling
Makoto Inoue, Md Harunor Rashid, Ryousuke Fujita, James J A Contos, Jerold Chun and Hiroshi Ueda Nature Medicine10, 712–718
(July 2004); doi:10.1038/nm1060
| Abstract | Full Text (HTML/PDF) |
article Dopamine depletion impairs precursor cell proliferation in Parkinson disease
Günter U Höglinger, Pamela Rizk, Marie P Muriel, Charles Duyckaerts, Wolfgang H Oertel, Isabelle Caille and Etienne C Hirsch Nature Neuroscience7, 726–735
(July 2004); doi:10.1038/nn1265
| Abstract | Full Text (HTML/PDF) |
review article State-dependent opioid control of pain
Howard Fields Nature Reviews Neuroscience5, 565–575
(July 2004); doi:10.1038/nrn1431
| Abstract | Full Text (HTML / PDF) |
news and views Cannabinoids cool the intestine
George Kunos and Pál Pacher Nature Medicine10, 678–679
(July 2004); doi:10.1038/nm0704-678
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twenty questions The state of GPCR research in 2004 Nature Reviews Drug Discovery3, 577–626
(July 2004); doi:10.1038/nrd1458
| Abstract | Full Text (HTML / PDF) |
article Sphingosine 1-phosphate receptor 1 promotes B cell localization in the splenic marginal zone
Guy Cinamon, Mehrdad Matloubian, Matthew J Lesneski, Ying Xu, Caroline Low, Theresa Lu, Richard L Proia and Jason G Cyster Nature Immunology5, 713–720
(July 2004); doi:10.1038/ni1083
| Abstract | Full Text (HTML/PDF) |
news and views Should we B-leavin' now?
Michael D Gunn and Garnett Kelsoe Nature Immunology5, 703–704
(July 2004); doi:10.1038/ni0704-703
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June
letter 3-Iodothyronamine is an endogenous and rapid-acting derivative of thyroid hormone
Thomas S Scanlan, Katherine L Suchland, Matthew E Hart, Grazia Chiellini, Yong Huang, Paul J Kruzich, Sabina Frascarelli, Dane A Crossley, II James R Bunzow, Simonetta Ronca-Testoni, Emil T Lin, Daniel Hatton, Riccardo Zucchi and David K Grandy Nature Medicine10, 638–642
(June 2004); doi:10.1038/nm1051
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news and views The two-timing thyroid
Stephen B Liggett Nature Medicine10, 582–583
(June 2004); doi:10.1038/nm0604-582
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review article Serotonergic neurons as carbon dioxide sensors that maintain ph homeostasis
George B. Richerson Nature Reviews Neuroscience5, 449–461
(June 2004); doi:10.1038/nrn1409
| Abstract | Full Text (HTML / PDF) |
letters to nature Enhanced partner preference in a promiscuous species by manipulating the expression of a single gene
Miranda M. Lim, Zuoxin Wang, Daniel E. Olazábal, Xianghui Ren, Ernest F. Terwilliger and Larry J. Young Nature429, 754–757
(17 June 2004); doi:10.1038/nature02539
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news and views Neurobiology: Why voles stick together
Evan Balaban Nature429, 711–712
(17 June 2004); doi:10.1038/429711a
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letter The endogenous ligand Stunted of the GPCR Methuselah extends lifespan in Drosophila
Svetlana Cvejic, Zheng Zhu, Sarah J. Felice, Yemiliya Berman and Xin-Yun Huang Nature Cell Biology6, 540–546
(June 2004); doi:10.1038/ncb1133
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article Induction of PGE2 by estradiol mediates developmental masculinization of sex behavior
Stuart K Amateau and Margaret M McCarthy Nature Neuroscience7, 643–650
(June 2004); doi:10.1038/nn1254
| Abstract | Full Text (HTML/PDF) |
news and views Brain gender: prostaglandins have their say
Erich N Ottem, Damian G Zuloaga and S Marc Breedlove Nature Neuroscience7, 570–572
(June 2004); doi:10.1038/nn0604-570
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article Mechanical stress activates angiotensin II type 1 receptor without the involvement of angiotensin II
Yunzeng Zou, Hiroshi Akazawa, Yingjie Qin, Masanori Sano, Hiroyuki Takano, Tohru Minamino, Noriko Makita, Koji Iwanaga, Weidong Zhu, Sumiyo Kudoh, Haruhiro Toko, Koichi Tamura, Minoru Kihara, Toshio Nagai, Akiyoshi Fukamizu, Satoshi Umemura, Taroh Iiri, Toshiro Fujita and Issei Komuro Nature Cell Biology6, 499–506
(June 2004); doi:10.1038/ncb1137
| Abstract | Full Text (HTML/PDF) |
May
article FAPPs control Golgi-to-cell-surface membrane traffic by binding to ARF and PtdIns(4)P
Anna Godi, Antonella Di Campli, Athanasios Konstantakopoulos, Giuseppe Di Tullio, Dario R. Alessi, Gursant S. Kular, Tiziana Daniele, Pierfrancesco Marra, John M. Lucocq and M. Antonietta De Matteis Nature Cell Biology6, 393–404
(May 2004); doi:10.1038/ncb1119
| Abstract | Full Text (HTML/PDF) |
news and views New candidates for vesicle coat proteins
Michael Roth Nature Cell Biology6, 384–385
(May 2004); doi:10.1038/ncb0504-384
| Full Text (HTML/PDF) |
letters to nature Rab5 is a signalling GTPase involved in actin remodelling by receptor tyrosine kinases
Letizia Lanzetti, Andrea Palamidessi, Liliana Areces, Giorgio Scita and Pier Paolo Di Fiore Nature429, 309–314
(20 May 2004); doi:10.1038/nature02542
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review article RAS and RHO GTPases in G1-phase cell-cycle regulation
Mathew L. Coleman, Christopher J. Marshall and Michael F. Olson Nature Reviews Molecular Cell Biology5, 355–366
(May 2004); doi:10.1038/nrm1365
| Abstract | Full Text (HTML / PDF) |
letters to nature Citric acid cycle intermediates as ligands for orphan G-protein-coupled receptors
Weihai He, Frederick J.-P. Miao, Daniel C.-H. Lin, Ralf T. Schwandner, Zhulun Wang, Jinhai Gao, Jin-Long Chen, Hui Tian and Lei Ling Nature429, 188–193
(13 May 2004); doi:10.1038/nature02488
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news and views Physiology: Orphan detectors of metabolism
Steven C. Hebert Nature429, 143–145
(13 May 2004); doi:10.1038/429143a
| Full Text (HTML / PDF) |
letters to nature The GTPase-activating protein Rap1GAP uses a catalytic asparagine
Oliver Daumke, Michael Weyand, Partha P. Chakrabarti, Ingrid R. Vetter and Alfred Wittinghofer Nature429, 197–201
(13 May 2004); doi:10.1038/nature02505
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news and views Signal transduction: Thumbs up for inactivation
Holger Rehmann and Johannes L. Bos Nature429, 138–139
(13 May 2004); doi:10.1038/429138a
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news and views Membrane trafficking: Dual-key strategy
Toshiki Itoh and Pietro De Camilli Nature429, 141–143
(13 May 2004); doi:10.1038/429141a
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article Targeting of the Arf-like GTPase Arl3p to the Golgi requires N-terminal acetylation and the membrane protein Sys1p
Rudy Behnia, Bojana Panic, James R. C. Whyte and Sean Munro Nature Cell Biology6, 405–413
(May 2004); doi:10.1038/ncb1120
| Abstract | Full Text (HTML/PDF) |
article Golgi targeting of ARF-like GTPase Arl3p requires its Nα-acetylation and the integral membrane protein Sys1p
Subba Rao Gangi Setty, Todd I. Strochlic, Amy Hin Yan Tong, Charles Boone and Christopher G. Burd Nature Cell Biology6, 414–419
(May 2004); doi:10.1038/ncb1121
| Abstract | Full Text (HTML/PDF) |
news and views N-terminal acetylation targets GTPases to membranes
Catherine L. Jackson Nature Cell Biology6, 379–380
(May 2004); doi:10.1038/ncb0504-379
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April
review article Molecular targets in pituitary tumours
Anthony P. Heaney and Shlomo Melmed Nature Reviews Cancer4, 285–295
(April 2004); doi:10.1038/nrc1320
| Abstract | Full Text (HTML / PDF) |
article Rb regulates proliferation and rod photoreceptor development in the mouse retina
Jiakun Zhang, Jonathan Gray, Lizhao Wu, Gustavo Leone, Sheldon Rowan, Constance L Cepko, Xuemei Zhu, Cheryl M Craft and Michael A Dyer Nature Genetics36, 351–360
(April 2004); doi:10.1038/ng1318
| Abstract | Full Text (HTML/PDF) |
article The X-linked mental retardation protein oligophrenin-1 is required for dendritic spine morphogenesis
Eve-Ellen Govek, Sarah E Newey, Colin J Akerman, Justin R Cross, Lieven Van der Veken and Linda Van Aelst Nature Neuroscience7, 364–372
(April 2004); doi:10.1038/nn1210
| Abstract | Full Text (HTML/PDF) |
research article Reversible site-selective labeling of membrane proteins in live cells
Emmanuel G Guignet, Ruud Hovius and Horst Vogel Nature Biotechnology22, 440–444
(April 2004); doi:10.1038/nbt954
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news and views Finding needles in haystacks
Jonathan A Javitch Nature Biotechnology22, 394–396
(April 2004); doi:10.1038/nbt0404-394
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brief communication Effective treatment of an orthologous model of autosomal dominant polycystic kidney disease
Vicente E Torres, Xiaofang Wang, Qi Qian, Stefan Somlo, Peter C Harris, Vincent H Gattone and II Nature Medicine10, 363–364
(April 2004); doi:10.1038/nm1004
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article Defective lipoxin-mediated anti-inflammatory activity in the cystic fibrosis airway
Christopher L Karp, Leah M Flick, Kiwon W Park, Samir Softic, Todd M Greer, Raquel Keledjian, Rong Yang, Jasim Uddin, William B Guggino, Sowsan F Atabani, Yasmine Belkaid, Yan Xu, Jeffrey A Whitsett, Frank J Accurso, Marsha Wills-Karp and Nicos A Petasis Nature Immunology5, 388–392
(April 2004); doi:10.1038/ni1056
| Abstract | Full Text (HTML/PDF) |
news and views New therapeutic key for cystic fibrosis: a role for lipoxins
Daiya Takai, Takahide Nagase and Takao Shimizu Nature Immunology5, 357–358
(April 2004); doi:10.1038/ni0404-357
| Full Text (HTML/PDF) |
brief communication Cholecystokinin-mediated suppression of feeding involves the brainstem melanocortin system
Wei Fan, Kate L J Ellacott, Ilia G Halatchev, Kanji Takahashi, Pinxuan Yu and Roger D Cone Nature Neuroscience7, 335–336
(April 2004); doi:10.1038/nn1214
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review article Genes and ligands for odorant, vomeronasal and taste receptors
Peter Mombaerts Nature Reviews Neuroscience5, 263–278
(April 2004); doi:10.1038/nrn1365
| Abstract | Full Text (HTML / PDF) |
letter Abi1 is essential for the formation and activation of a WAVE2 signalling complex
Metello Innocenti, Adriana Zucconi, Andrea Disanza, Emanuela Frittoli, Liliana B. Areces, Anika Steffen, Theresia E. B. Stradal, Pier Paolo Di Fiore, Marie-France Carlier and Giorgio Scita Nature Cell Biology6, 319–327
(April 2004); doi:10.1038/ncb1105
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news and views Solving the WAVE function
Simone L. Blagg and Robert H. Insall Nature Cell Biology6, 279–281
(April 2004); doi:10.1038/ncb0404-279
| Full Text (HTML/PDF) |
March
article LINGO-1 is a component of the Nogo-66 receptor/p75 signaling complex
Sha Mi, Xinhua Lee, Zhaohui Shao, Greg Thill, Benxiu Ji, Jane Relton, Melissa Levesque, Norm Allaire, Steve Perrin, Bryan Sands, Thomas Crowell, Richard L Cate, John M McCoy and R Blake Pepinsky Nature Neuroscience7, 221–228
(March 2004); doi:10.1038/nn1188
| Abstract | Full Text (HTML/PDF) |
article Counterion displacement in the molecular evolution of the rhodopsin family
Akihisa Terakita, Mitsumasa Koyanagi, Hisao Tsukamoto, Takahiro Yamashita, Takashi Miyata and Yoshinori Shichida Nature Structural and Molecular Biology11, 284–289
(March 2004); doi:10.1038/nsmb731
| Abstract | Full Text (HTML/PDF) |
article The gene encoding 5-lipoxygenase activating protein confers risk of myocardial infarction and stroke
Anna Helgadottir, Andrei Manolescu, Gudmar Thorleifsson, Solveig Gretarsdottir, Helga Jonsdottir, Unnur Thorsteinsdottir, Nilesh J Samani, Gudmundur Gudmundsson, Struan F A Grant, Gudmundur Thorgeirsson, Sigurlaug Sveinbjornsdottir, Einar M Valdimarsson, Stefan E Matthiasson, Halldor Johannsson, Olof Gudmundsdottir, Mark E Gurney, Jesus Sainz, Margret Thorhallsdottir, Margret Andresdottir, Michael L Frigge, Eric J Topol, Augustine Kong, Vilmundur Gudnason, Hakon Hakonarson, Jeffrey R Gulcher & Kari Stefansson Nature Genetics36, 233–239
(March 2004); doi:10.1038/ng1311
| Abstract | Full Text (HTML/PDF) |
letter Abl-dependent tyrosine phosphorylation of Sos-1 mediates growth-factor-induced Rac activation
Patrizia Sini, Angela Cannas, Anthony J. Koleske, Pier Paolo Di Fiore and Giorgio Scita Nature Cell Biology6, 268–275
(March 2004); doi:10.1038/ncb1096
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article ERM proteins regulate cytoskeleton relaxation promoting T cell-APC conjugation
Sophie Faure, Laura Inés Salazar-Fontana, Monique Semichon, Victor L J Tybulewicz, Georges Bismuth, Alain Trautmann, Ronald N Germain and Jérôme Delon Nature Immunology5, 272–279
(March 2004); doi:10.1038/ni1039
| Abstract | Full Text (HTML/PDF) |
February
letters to nature Sortilin is essential for proNGF-induced neuronal cell death
Anders Nykjaer, Ramee Lee, Kenneth K. Teng, Pernille Jansen, Peder Madsen, Morten S. Nielsen, Christian Jacobsen, Marco Kliemannel, Elisabeth Schwarz, Thomas E. Willnow, Barbara L. Hempstead and Claus M. Petersen Nature427, 843–848
(26 February 2004); doi:10.1038/nature02319
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news and views Neurobiology: A move to sort life from death
David R. Kaplan and Freda D. Miller Nature427, 798–799
(26 February 2004); doi:10.1038/427798a
| Full Text (HTML / PDF) |
article PAF-mediated pulmonary edema: a new role for acid sphingomyelinase and ceramide
Rolf Göggel, Supandi Winoto-Morbach, Gabriele Vielhaber, Yumiko Imai, Karsten Lindner, Lore Brade, Helmut Brade, Stefan Ehlers, Arthur S Slutsky, Stefan Schütze, Erich Gulbins and Stefan Uhlig Nature Medicine10, 155–160
(February 2004); doi:10.1038/nm977
| Abstract | Full Text (HTML/PDF) |
news and views Ceramide lances the lungs
Peter J Barnes Nature Medicine10, 130–131
(February 2004); doi:10.1038/nm0204-130
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article Agonist-independent modulation of N-type calcium channels by ORL1 receptors
Aaron M Beedle, John E McRory, Olivier Poirot, Clinton J Doering, Christophe Altier, Christian Barrere, Jawed Hamid, Joel Nargeot, Emmanuel Bourinet and Gerald W Zamponi Nature Neuroscience7, 118–125
(February 2004); doi:10.1038/nn1180
| Abstract | Full Text (HTML/PDF) |
brief communication Evolutionary genetics: CCR5 mutation and plague protection
Joan Mecsas, Greg Franklin, William A. Kuziel, Robert R. Brubaker, Stanley Falkow and Donald E. Mosier Nature427, 606
(12 February 2004); doi:10.1038/427606a
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article Identification of amino acid residues crucial for chemokine receptor dimerization
Patricia Hernanz-Falcón, José Miguel Rodríguez-Frade, Antonio Serrano, David Juan, Antonio del Sol, Silvia F Soriano, Fernando Roncal, Lucio Gómez, Alfonso Valencia, Carlos Martínez-A and Mario Mellado Nature Immunology5, 216–223
(February 2004); doi:10.1038/ni1027
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review article The dark side of C5a in sepsis
Peter A. Ward Nature Reviews Immunology4, 133–142
(February 2004); doi:10.1038/nri1269
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review article cAMP detection methods in HTS: selecting the best from the rest
Christine Williams Nature Reviews Drug Discovery3, 125–135
(February 2004); doi:10.1038/nrd1306
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January
article Structural basis for recruitment of GRIP domain golgin-245 by small GTPase Arl1
Mousheng Wu, Lei Lu, Wanjin Hong and Haiwei Song Nature Structural and Molecular Biology11, 86–94
(January 2004); doi:10.1038/nsmb714
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letters to nature Lymphocyte egress from thymus and peripheral lymphoid organs is dependent on S1P receptor 1
Mehrdad Matloubian, Charles G. Lo, Guy Cinamon, Matthew J. Lesneski, Ying Xu, Volker Brinkmann, Maria L. Allende, Richard L. Proia and Jason G. Cyster Nature427, 355–360
(22 January 2004); doi:10.1038/nature02284
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letters to nature Ras regulates assembly of mitogenic signalling complexes through the effector protein IMP
Sharon A. Matheny, Chiyuan Chen, Robert L. Kortum, Gina L. Razidlo, Robert E. Lewis and Michael A. White Nature427, 256–260
(15 January 2004); doi:10.1038/nature02237
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review article Tubby proteins: the plot thickens
Kilpatrick Carroll, Carlos Gomez and Lawrence Shapiro Nature Reviews Molecular Cell Biology5, 55–64
(January 2004); doi:10.1038/nrm1278
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letters to nature Defects in RGS9 or its anchor protein R9AP in patients with slow photoreceptor deactivation
Koji M. Nishiguchi, Michael A. Sandberg, Aart C. Kooijman, Kirill A. Martemyanov, Jan W. R. Pott, Stephanie A. Hagstrom, Vadim Y. Arshavsky, Eliot L. Berson and Thaddeus P. Dryja Nature427, 75–78
(01 January 2004); doi:10.1038/nature02170
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news and views Vision: The need for speed
Kendall J. Blumer Nature427, 20–21
(01 January 2004); doi:10.1038/427020a
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