article mPins modulates PSD-95 and SAP102 trafficking and influences NMDA receptor surface expression
Nathalie Sans, Philip Y. Wang, Quansheng Du, Ronald S. Petralia, Ya-Xian Wang, Sajan Nakka, Joe B. Blumer, Ian G. Macara and Robert J. Wenthold Nature Cell Biology7, 1179–1190
(December 2005); doi:10.1038/ncb1325
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news and views Pins for spines
Juergen A. Knoblich Nature Cell Biology7, 1157–1158
(December 2005); doi:10.1038/ncb1205-1057
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November
letter Drosophila Ric-8 regulates Gαi cortical localization to promote Gαi-dependent planar orientation of the mitotic spindle during asymmetric cell division
Nicolas B. David, Charlotte A. Martin, Marion Segalen, François Rosenfeld, François Schweisguth and Yohanns Bellaïche Nature Cell Biology7, 1083–1090
(November 2005); doi:10.1038/ncb1319
| Abstract
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letter Ric-8 controls Drosophila neural progenitor asymmetric division by regulating heterotrimeric G proteins
Hongyan Wang, Kian Hong Ng, Hongliang Qian, David P. Siderovski, William Chia and Fengwei Yu Nature Cell Biology7, 1091–1098
(November 2005); doi:10.1038/ncb1317
| Abstract
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letter Drosophila Ric-8 is essential for plasma-membrane localization of heterotrimeric G proteins
Bernhard Hampoelz, Oliver Hoeller, Sarah K. Bowman, Dara Dunican and Juergen A. Knoblich Nature Cell Biology7, 1099–1105
(November 2005); doi:10.1038/ncb1318
| Abstract
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news and views Drosophila G-protein signalling: intricate roles for Ric-8?
Fumio Matsuzaki Nature Cell Biology7, 1047–1049
(November 2005); doi:10.1038/ncb1105-1047
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October
article The N-end rule pathway as a nitric oxide sensor controlling the levels of multiple regulators
Rong-Gui Hu, Jun Sheng, Xin Qi, Zhenming Xu, Terry T. Takahashi and Alexander Varshavsky Nature437, 981–986
(13 October 2005); doi:10.1038/nature04027
| Abstract | Full Text (HTML / PDF) |
September
article Psoriasis-like skin disease and arthritis caused by inducible epidermal deletion of Jun proteins
Rainer Zenz, Robert Eferl, Lukas Kenner, Lore Florin, Lars Hummerich, Denis Mehic, Harald Scheuch, Peter Angel, Erwin Tschachler and Erwin F. Wagner Nature437, 369–375
(15 September 2005); doi:10.1038/nature03963
| Abstract | Full Text (HTML / PDF) |
review article Developmental Cell Biology: G Proteins in Development
Craig C. Malbon Nature Reviews Molecular Cell Biology6, 689–701
(September 2005); doi:10.1038/nrm1716
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article A crucial role for GRK2 in regulation of endothelial cell nitric oxide synthase function in portal hypertension
Songling Liu, Richard T Premont, Christopher D Kontos, Shoukang Zhu and Don C Rockey Nature Medicine11, 952–958
(September 2005); doi:10.1038/nm1289
| Abstract | Full Text (HTML/PDF) |
article Activation of GPCRs modulates quantal size in chromaffin cells through Gβγ and PKC
Xiao-Ke Chen, Lie-Cheng Wang, Yang Zhou, Qian Cai, Murali Prakriya, Kai-Lai Duan, Zu-Hang Sheng, Christopher Lingle and Zhuan Zhou Nature Neuroscience8, 1160–1168
(September 2005); doi:10.1038/nn1529
| Abstract | Full Text (HTML/PDF) |
July
review article Sphingosine 1-phosphate and its receptors: an autocrine and paracrine network
Hugh Rosen and Edward J. Goetzl Nature Reviews Immunology5, 560–570
(July 2005); doi:10.1038/nri1650
| Abstract | Full Text (HTML / PDF) |
June
article Caenorhabditis elegans RME-6 is a novel regulator of RAB-5 at the clathrin-coated pit
Miyuki Sato, Ken Sato, Paul Fonarev, Chih-Jen Huang, Willisa Liou and Barth D. Grant Nature Cell Biology7, 559–569
(June 2005); doi:10.1038/ncb1261
| Abstract | Full Text (HTML/PDF) |
news and views A sixth sense for Rab5
Alexander M. van der Bliek Nature Cell Biology7, 548–550
(June 2005); doi:10.1038/ncb0605-548
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brief communication An inducible translocation strategy to rapidly activate and inhibit small GTPase signaling pathways
Takanari Inoue, Won Do Heo, Joshua S Grimley, Thomas J Wandless and Tobias Meyer Nature Methods2, 415–418
(June 2005); doi:10.1038/nmeth763
| Abstract | Full Text (HTML/PDF) |
article RNA editing produces glycine receptor α3P185L, resulting in high agonist potency
Jochen C Meier, Christian Henneberger, Igor Melnick, Claudia Racca, Robert J Harvey, Uwe Heinemann, Volker Schmieden and Rosemarie Grantyn Nature Neuroscience8, 736–744
(June 2005); doi:10.1038/nn1467
| Abstract | Full Text (HTML/PDF) |
article Endocannabinoid signaling depends on the spatial pattern of synapse activation
Païkan Marcaggi and David Attwell Nature Neuroscience8, 776–781
(June 2005); doi:10.1038/nn1458
| Abstract | Full Text (HTML/PDF) |
May
letter to nature Structural and mechanistic insights into the interaction between Rho and mammalian Dia
R. Rose, M. Weyand, M. Lammers, T. Ishizaki, M. R. Ahmadian and A. Wittinghofer Nature435, 513–518
(26 May 2005); doi:10.1038/nature03604
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article T cell costimulation by chemokine receptors
Barbara Molon, Giorgia Gri, Monica Bettella, Concepción Gómez-Moutón, Antonio Lanzavecchia, Carlos Martínez-A, Santos Mañes and Antonella Viola Nature Immunology6, 465–471
(May 2005); doi:10.1038/ni1191
| Abstract | Full Text (HTML/PDF) |
review article Bacterial cytotoxins: targeting eukaryotic switches
Klaus Aktories and Joseph T. Barbieri Nature Reviews Microbiology12, 397–410
(May 2005); doi:10.1038/nrmicro1150
| Abstract | Full Text (HTML/PDF) |
article Actin and Arf1-dependent recruitment of a cortactin-dynamin complex to the Golgi regulates post-Golgi transport
Hong Cao, Shaun Weller, James D. Orth, Jing Chen, Bing Huang, Ji-Long Chen, Mark Stamnes and Mark A. McNiven Nature Cell Biology7, 483–492
(May 2005); doi:10.1038/ncb1246
| Abstract | Full Text (HTML/PDF) |
news and views Extending the court for cortactin: from the cortex to the Golgi
Michael M. Kessels and Britta Qualmann Nature Cell Biology7, 448–449
(May 2005); doi:10.1038/ncb0505-448
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article Gβγ acts at the C terminus of SNAP-25 to mediate presynaptic inhibition
Tatyana Gerachshenko, Trillium Blackmer, Eun-Ja Yoon, Cheryl Bartleson, Heidi E Hamm and Simon Alford Nature Neuroscience8, 597–605
(May 2005); doi:10.1038/nn1439
| Abstract | Full Text (HTML/PDF) |
news and views Finding the G spot on fusion machinery
Jane Sullivan Nature Neuroscience8, 542–544
(May 2005); doi:10.1038/nn0505-542
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April
article An α4 integrin-paxillin-Arf-GAP complex restricts Rac activation to the leading edge of migrating cells
Naoyuki Nishiya, William B. Kiosses, Jaewon Han and Mark H. Ginsberg Nature Cell Biology7, 343–352
(April 2005); doi:10.1038/ncb1234
| Abstract | Full Text (HTML/PDF) |
news and views Cell polarization mechanisms during directed cell migration
Anna Huttenlocher Nature Cell Biology7, 336–337
(April 2005); doi:10.1038/ncb0405-336
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letter Spinophilin regulates Ca2+ signalling by binding the N-terminal domain of RGS2 and the third intracellular loop of G-protein-coupled receptors
Xinhua Wang, Weizhong Zeng, Abigail A. Soyombo, Wei Tang, Elliott M. Ross, Anthony P. Barnes, Sharon L. Milgram, Josef M. Penninger, Patrick B. Allen, Paul Greengard and Shmuel Muallem Nature Cell Biology7, 405–411
(April 2005); doi:10.1038/ncb1237
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article Essential role for the second extracellular loop in C5a receptor activation
Jeffery M Klco, Christina B Wiegand, Kirk Narzinski and Thomas J Baranski Nature Structural and Molecular Biology12, 320–326
(April 2005); doi:10.1038/nsmb913
| Abstract | Full Text (HTML/PDF) |
news and views The second extracellular loop: a damper for G protein-coupled receptors?
Dominique Massotte and Brigitte L Kieffer Nature Structural and Molecular Biology12, 287–288
(April 2005); doi:10.1038/nsmb0405-287
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news and views Directing NGF's actions: it's a Rap
Philip J. S. Stork Nature Cell Biology7, 338–339
(April 2005); doi:10.1038/ncb0405-338
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article Calmodulin kinase II inhibition protects against structural heart disease
Rong Zhang, Michelle S C Khoo, Yuejin Wu, Yingbo Yang, Chad E Grueter, Gemin Ni, Edward E Price, Jr. William Thiel, Silvia Guatimosim, Long-Sheng Song, Ernest C Madu, Anisha N Shah, Tatiana A Vishnivetskaya, James B Atkinson, Vsevolod V Gurevich, Guy Salama, W J Lederer, Roger J Colbran and Mark E Anderson Nature Medicine11, 409–417
(April 2005); doi:10.1038/nm1215
| Abstract | Full Text (HTML/PDF) |
news and views Beyond beta blockers
Donald M Bers Nature Medicine11, 379–380
(April 2005); doi:10.1038/nm0405-379
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article Golgi-localized GAP for Cdc42 functions downstream of ARF1 to control Arp2/3 complex and F-actin dynamics
Thierry Dubois, Olivia Paléotti, Alexander A. Mironov, Jr Vincent Fraisier, Theresia E. B. Stradal, Maria Antonietta De Matteis, Michel Franco and Philippe Chavrier Nature Cell Biology7, 353–364
(April 2005); doi:10.1038/ncb1244
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letter Regulation of PTEN by Rho small GTPases
Zhong Li, Xiemei Dong, Zhenglong Wang, Wenzhong Liu, Ning Deng, Yu Ding, Liuya Tang, Tim Hla, Rong Zeng, Lin Li and Dianqing Wu Nature Cell Biology7, 399–404
(April 2005); doi:10.1038/ncb1236
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news and views Rho Rocks PTEN
Ruedi Meili, Atsuo T. Sasaki and Richard A. Firtel Nature Cell Biology7, 334–335
(April 2005); doi:10.1038/ncb0405-334
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article G protein βγ directly regulates SNARE protein fusion machinery for secretory granule exocytosis
Trillium Blackmer, Eric C Larsen, Cheryl Bartleson, Judith A Kowalchyk, Eun-Ja Yoon, Anita M Preininger, Simon Alford, Heidi E Hamm and Thomas F J Martin Nature Neuroscience8, 421–425
(April 2005); doi:10.1038/nn1423
| Abstract | Full Text (HTML/PDF) |
article Vav3 regulates osteoclast function and bone mass
Roberta Faccio, Steven L Teitelbaum, Keiko Fujikawa, Jean Chappel, Alberta Zallone, Victor L Tybulewicz, F Patrick Ross and Wojciech Swat Nature Medicine11, 284–290
(March 2005); doi:10.1038/nm1194
| Abstract | Full Text (HTML/PDF) |
brief communication Mutations of the catalytic subunit of RAB3GAP cause Warburg Micro syndrome
Irene A Aligianis, Colin A Johnson, Paul Gissen, Dongrong Chen, Daniel Hampshire, Katrin Hoffmann, Esther N Maina, Neil V Morgan, Louise Tee, Jenny Morton, John R Ainsworth, Denise Horn, Elisabeth Rosser, Trevor R P Cole, Irene Stolte-Dijkstra, Karen Fieggen, Jill Clayton-Smith, André Mégarbané, Julian P Shield, Ruth Newbury-Ecob, William B Dobyns, John M Graham, Jr Klaus W Kjaer, Mette Warburg, Jacqueline Bond, Richard C Trembath, Laura W Harris, Yoshimi Takai, Stefan Mundlos, David Tannahill, C Geoffery Woods and Eamonn R Maher Nature Genetics37, 221–224
(March 2005); doi:10.1038/ng1517
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March
news and views Some assembly required
Mark L Mayer Nature Structural and Molecular Biology12, 208–209
(March 2005); doi:10.1038/nsmb0305-208
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news and views Global conformational rearrangements during the activation of the GDP/GTP exchange factor Vav3
Óscar Llorca, Ernesto Arias-Palomo, José L Zugaza and Xosé R Bustelo EMBO JournalAOP,
(10 March 2005); doi:10.1038/sj.emboj.7600617
| Abstract | Full Text (HTML/PDF) |
letter Par-3 controls tight junction assembly through the Rac exchange factor Tiam1
Xinyu Chen and Ian G. Macara Nature Cell Biology7, 262–269
(March 2005); doi:10.1038/ncb1226
| First Paragraph | Full Text (HTML/PDF) |
letter PAR-6-PAR-3 mediates Cdc42-induced Rac activation through the Rac GEFs STEF/Tiam1
Takashi Nishimura, Tomoya Yamaguchi, Katsuhiro Kato, Masato Yoshizawa, Yo-ichi Nabeshima, Shigeo Ohno, Mikio Hoshino and Kozo Kaibuchi Nature Cell Biology7, 270–277
(March 2005); doi:10.1038/ncb1227
| First Paragraph | Full Text (HTML/PDF) |
news and views Pars and polarity: taking control of Rac
Toby W. Hurd and Ben Margolis Nature Cell Biology7, 205–207
(March 2005); doi:10.1038/ncb0305-205
| Full Text (HTML/PDF) |
letter Nephrocystin-5, a ciliary IQ domain protein, is mutated in Senior-Loken syndrome and interacts with RPGR and calmodulin
Edgar A Otto, Bart Loeys, Hemant Khanna, Jan Hellemans, Ralf Sudbrak, Shuling Fan, Ulla Muerb, John F O'Toole, Juliana Helou, Massimo Attanasio, Boris Utsch, John A Sayer, Concepcion Lillo, David Jimeno, Paul Coucke, Anne De Paepe, Richard Reinhardt, Sven Klages, Motoyuki Tsuda, Isao Kawakami, Takehiro Kusakabe, Heymut Omran, Anita Imm, Melissa Tippens, Pamela A Raymond, Jo Hill, Phil Beales, Shirley He, Andreas Kispert, Benjamin Margolis, David S Williams, Anand Swaroop and Friedhelm Hildebrandt Nature Genetics37, 282–288
(March 2005); doi:10.1038/ng1520
| First Paragraph | Full Text (HTML/PDF) |
article A FlAsH-based FRET approach to determine G protein-coupled receptor activation in living cells
Carsten Hoffmann, Guido Gaietta, Moritz Bünemann, Stephen R Adams, Silke Oberdorff-Maass, Björn Behr, Jean-Pierre Vilardaga, Roger Y Tsien, Mark H Ellisman and Martin J Lohse Nature Methods2, 171–176
(2005); doi:10.1038/nmeth742
| Abstract | Full Text (HTML/PDF) |
article Real-time monitoring of receptor and G-protein interactions in living cells
Céline Galés, R Victor Rebois, Mireille Hogue, Phan Trieu, Andreas Breit, Terence E Hébert, 3 and Michel Bouvier Nature Methods2, 177–184
(March 2005); doi:10.1038/nmeth743
| Abstract | Full Text (HTML/PDF) |
news and views New eyes to see texture in ligand efficacy
Terry P Kenakin Nature Methods2, 163–164
(March 2005); doi:10.1038/nmeth0305-163.html
| Abstract | Full Text (HTML/PDF) |
letters to nature Two pathways converge at CED-10 to mediate actin rearrangement and corpse removal in C. elegans
Jason M. Kinchen , Juan Cabello, Doris Klingele, Kelvin Wong, Richard Feichtinger, Heinke Schnabel, Ralf Schnabel and Michael O. Hengartner Nature434, 93–99
(03 March 2005); doi:10.1038/nature03263
| First Paragraph | Full Text (HTML / PDF) |
letter Cdc42-MRCK and Rho-ROCK signalling cooperate in myosin phosphorylation and cell invasion
Simon Wilkinson, Hugh F. Paterson and Christopher J. Marshall Nature Cell Biology7, 255–261
(March 2005); doi:10.1038/ncb1230
| First Paragraph | Full Text (HTML/PDF) |
article Dynamin 2 regulates T cell activation by controlling actin polymerization at the immunological synapse
Timothy S Gomez, Michael J Hamann, Sean McCarney, Doris N Savoy, Casey M Lubking, Michael P Heldebrant, Christine M Labno, David J McKean, Mark A McNiven, Janis K Burkhardt and Daniel D Billadeau Nature Immunology6, 261–270
(March 2005); doi:10.1038/ni1168
| Abstract | Full Text (HTML/PDF) |
February
article Structure of the p115RhoGEF rgRGS domain-Gα13/i1 chimera complex suggests convergent evolution of a GTPase activator
Zhe Chen, William D Singer, Paul C Sternweis and Stephen R Sprang Nature Structural and Molecular Biology12, 191–197
(February 2005); doi:10.1038/nsmb888
| Abstract | Full Text (HTML/PDF) |
article Ras binding opens c-Raf to expose the docking site for mitogen-activated protein kinase kinase
Kenta Terai and Michiyuki Matsuda EMBO ReportsAOP
(11 February 2005); doi:10.1038/sj.embor.7400349
| Abstract | Full Text (HTML/PDF) |
review article GEF means go: turning on RHO GTPases with guanine nucleotide-exchange factors
Kent L. Rossman , Channing J. Der and John Sondek Nature Reviews Molecular Cell Biology6, 167–180
(February 2005); doi:10.1038/nrm1587
| Summary | Full Text (HTML / PDF) |
review article Metabotropic glutamate receptors as novel targets for anxiety and stress disorders
Chad J. Swanson, Mark Bures, Michael P. Johnson, Anni-Maija Linden, James A. Monn and Darryle D. Schoepp Nature Reviews Drug Discovery4, 131–144
(February 2005); doi:10.1038/nrd1630
| Summary | Full Text (HTML / PDF) |
review article The histamine H3 receptor: from gene cloning to H3 receptor drugs
Rob Leurs, Remko A. Bakker, Henk Timmerman and Iwan J. P. de Esch Nature Reviews Drug Discovery AOP published online 24 January 2005; doi:10.1038/nrd1631
| Summary | Full Text (HTML / PDF) |
January
news and views Inflammation and cancer: the long reach of Ras
Michael Karin Nature Medicine11, 20–21
(January 2005); doi:10.1038/nm0105-20
| Full Text (HTML/PDF) |
article Wnt signaling through Dishevelled, Rac and JNK regulates dendritic development
Silvana B Rosso, Daniel Sussman, Anthony Wynshaw-Boris and Patricia C Salinas Nature Neuroscience8, 34–42
(January 2005); doi:10.1038/nn1374
| Abstract | Full Text (HTML/PDF) |
brief communication Odorant receptor heterodimerization in the olfactory system of Drosophila melanogaster
Eva M Neuhaus, Günter Gisselmann, Weiyi Zhang, Ruth Dooley, Klemens Störtkuhl and Hanns Hatt Nature Neuroscience8, 15–17
(January 2005); doi:10.1038/nn1371
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