Research library: G-protein/GPCR signaling
2007:
December
| November
| October
| September
| August
| July
| June
| May
| April
| March
| February
| January
Other Years: 2002 | 2003 | 2004 | 2005 | 2006 | 2008
December
review
Synergistic control of cell adhesion by integrins and syndecans
Mark R. Morgan, Martin J. Humphries & Mark D. Bass
Nature Reviews Molecular Cell Biology 8, 957–969
(December 2007); doi:10.1038/nrm2289
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article
Natural killer cell trafficking in vivo requires a dedicated sphingosine 1-phosphate receptor
Thierry Walzer et al.
Nature Immunology 8, 1337–1344
(December 2007); doi:10.1038/ni1523
| Summary | Full Text (HTML / PDF) |
article
Fibroblast-led collective invasion of carcinoma cells with differing roles for RhoGTPases in leading and following cells
Cedric Gaggioli et al.
Nature Cell Biology 9, 1392–1400
(December 2007); doi:10.1038/ncb1658
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news and views
Leading the charge
Derek C. Radisky
Nature Cell Biology 9, 1341–1342
(December 2007); doi:10.1038/ncb1207-1341
| Summary | Full Text (HTML / PDF) |
article
RGS2 modulates coupling between GABAB receptors and GIRK channels in dopamine neurons of the ventral tegmental area
Gwenaël Labouèbe et al.
Nature Neuroscience 10, 1559–1568
(December 2007); doi:10.1038/nn2006
| Summary | Full Text (HTML / PDF) |
November
letter
Spatial regulation of Fus3 MAP kinase activity through a reaction-diffusion mechanism in yeast pheromone signalling
Celine I. Maeder, Mark A. Hink, Ali Kinkhabwala, Reinhard Mayr, Philippe I. H. Bastiaens & Michael Knop
Nature Cell Biology 9, 1319–1326
(November 2007); doi:10.1038/ncb1652
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article
Control of planar divisions by the G-protein regulator LGN maintains progenitors in the chick neuroepithelium
Xavier Morin, Florence Jaouen & Pascale Durbec
Nature Neuroscience 10, 1440–1448
(November 2007); doi:10.1038/nn1984
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letter
An antidepressant that extends lifespan in adult Caenorhabditis elegans
Michael Petrascheck, Xiaolan Ye & Linda B. Buck
Nature 450, 553–556
(22 November 2007); doi:10.1038/nature05991
| Summary | Full Text (HTML / PDF) |
perspective
Chemokines: a new class of neuromodulator?
William Rostène, Patrick Kitabgi & Stéphane Mélik Parsadaniantz
Nature Reviews Neuroscience 8, 895–903
(November 2007); doi:10.1038/nrn2255
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article
Crystal structure of the human β2 adrenergic G-protein-coupled receptor
Søren G. F. Rasmussen et al.
Nature 450, 383–387
(15 November 2007); doi:10.1038/nature06325
| Summary | Full Text (HTML / PDF) |
news and views
Structural biology: A receptor unlocked
Stephen R. Sprang
Nature 450, 355–356
(15 November 2007); doi:10.1038/450355a
| Full Text (HTML / PDF) |
letter
Coupling of cortical dynein and Gα proteins mediates spindle positioning in Caenorhabditis elegans
Tu Nguyen-Ngoc, Katayoun Afshar & Pierre Gönczy
Nature Cell Biology 9, 1294–1302
(November 2007); doi:10.1038/ncb1649
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brief communication
A monoclonal antibody for G protein-coupled receptor crystallography
Peter W Day et al.
Nature Methods 4, 927–929
(November 2007); doi:10.1038/nmeth1112
| Summary | Full Text (HTML / PDF) |
October
article
Identification of stem cells in small intestine and colon by marker gene Lgr5
Nick Barker et al.
Nature 449, 1003–1007
(25 October 2007); doi:10.1038/nature06196
| Summary | Full Text (HTML / PDF) |
article
Catecholaminergic neurotransmitters regulate migration and repopulation of immature human CD34+ cells through Wnt signaling
Asaf Spiegel, Shoham Shivtiel, Alexander Kalinkovich, Aya Ludin, Neta Netzer, Polina Goichberg, Yaara Azaria, Igor Resnick, Izhar Hardan, Herzel Ben-Hur, Arnon Nagler, Menachem Rubinstein & Tsvee Lapidot
Nature Immunology 8, 1123–1131
(October 2007); doi:10.1038/ni1509
| Summary | Full Text (HTML / PDF) |
letter
Central control of bone remodeling by neuromedin U
Shingo Sato et al.
Nature Medicine 13, 1234–1240
(October 2007); doi:10.1038/nm1640
| Summary | Full Text (HTML / PDF) |
review
Exporting RNA from the nucleus to the cytoplasm
Alwin Köhler & Ed Hurt
Nature Reviews Molecular Cell Biology 8, 761–773
(October 2007); doi:10.1038/nrm2255
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article
T helper type 2 differentiation and intracellular trafficking of the interleukin 4 receptor-α subunit controlled by the Rac activator Dock2
Yoshihiko Tanaka et al.
Nature Immunology 8, 1067–1075
(October 2007); doi:10.1038/ni1506
| Summary | Full Text (HTML / PDF) |
letter
Phagocyte-derived catecholamines enhance acute inflammatory injury
Michael A. Flierl, Daniel Rittirsch, Brian A. Nadeau, Anthony J. Chen, J. Vidya Sarma, Firas S. Zetoune, Stephanie R. McGuire, Rachel P. List, Danielle E. Day, L. Marco Hoesel, Hongwei Gao, Nico Van Rooijen, Markus S. Huber-Lang, Richard R. Neubig & Peter A. Ward
Nature 449, 721–725
(11 October 2007); doi:10.1038/nature06185
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article
Mesenchymal stem cells within tumour stroma promote breast cancer metastasis
Antoine E. Karnoub, Ajeeta B. Dash, Annie P. Vo, Andrew Sullivan, Mary W. Brooks, George W. Bell, Andrea L. Richardson, Kornelia Polyak, Ross Tubo & Robert A. Weinberg
Nature 449, 557–563
(4 October 2007); doi:10.1038/nature06188
| Summary | Full Text (HTML / PDF) |
review
Evolving functions of endothelial cells in inflammation
Jordan S. Pober & William C. Sessa
Nature Reviews Immunology 7, 803–815
(October 2007); doi:10.1038/nri2171
| Summary | Full Text (HTML / PDF) |
September
brief communication
Cell type-specific gating of perisomatic inhibition by cholecystokinin
Csaba Földy, Soo Yeun Lee, János Szabadics, Axel Neu & Ivan Soltesz
Nature Neuroscience 10, 1128–1130
(September 2007); doi:10.1038/nn1952
| Summary | Full Text (HTML / PDF) |
brief communication
EP3 prostaglandin receptors in the median preoptic nucleus are critical for fever responses
Michael Lazarus, Kyoko Yoshida, Roberto Coppari, Caroline E Bass, Takatoshi Mochizuki, Bradford B Lowell & Clifford B Saper
Nature Neuroscience 10, 1131–1133
(September 2007); doi:10.1038/nn1949
| Summary | Full Text (HTML / PDF) |
article
Structural insight into filament formation by mammalian septins
Minhajuddin Sirajuddin, Marian Farkasovsky, Florian Hauer, Dorothee Kühlmann, Ian G. Macara, Michael Weyand, Holger Stark & Alfred Wittinghofer
Nature 449, 311–315
(20 September 2007); doi:10.1038/nature06052
| Summary | Full Text (HTML / PDF) |
article
Release of autoinhibition of ASEF by APC leads to CDC42 activation and tumor suppression
Natalia Mitin, Laurie Betts, Marielle E Yohe, Channing J Der, John Sondek & Kent L Rossman
Nature Structural & Molecular Biology 14, 814–823
(September 2007); doi:10.1038/nsmb1290
| Summary | Full Text (HTML / PDF) |
letter
Germline loss-of-function mutations in SPRED1 cause a neurofibromatosis 1-like phenotype
Hilde Brems, Magdalena Chmara, Mourad Sahbatou, Ellen Denayer, Koji Taniguchi, Reiko Kato, Riet Somers, Ludwine Messiaen, Sofie De Schepper, Jean-Pierre Fryns, Jan Cools, Peter Marynen, Gilles Thomas, Akihiko Yoshimura & Eric Legius
Nature Genetics 39, 1120–1126
(2007); doi:10.1038/ng2113
| Summary | Full Text (HTML / PDF) |
August
article
Plasma membrane nanoswitches generate high-fidelity Ras signal transduction
Tianhai Tian, Angus Harding, Kerry Inder, Sarah Plowman, Robert G. Parton & John F. Hancock
Nature Cell Biology 9, 905–914
(August 2007); doi:10.1038/ncb1615
| Summary | Full Text (HTML / PDF) |
news and views
Nanoclusters digitize Ras signalling
Anne K. Kenworthy
Nature Cell Biology 9, 875–877
(August 2007); doi:10.1038/ncb0807-875
| Summary | Full Text (HTML / PDF) |
article
A hippocampal Cdk5 pathway regulates extinction of contextual fear
Farahnaz Sananbenesi, Andre Fischer, Xinyu Wang, Christina Schrick, Rachael Neve, Jelena Radulovic & Li-Huei Tsai
Nature Neuroscience 10, 1012–1019
(August 2007); doi:10.1038/nn1943
| Summary | Full Text (HTML / PDF) |
review
Small-molecule therapies for cardiac hypertrophy: moving beneath the cell surface
Timothy A. McKinsey & David A. Kass
Nature Reviews Drug Discovery 6, 617–635
(August 2007); doi:10.1038/nrd2193
| Summary | Full Text (HTML / PDF) |
brief communication
Molecular genetic visualization of a rare subset of unmyelinated sensory neurons that may detect gentle touch
Qin Liu, Sophia Vrontou, Frank L Rice, Mark J Zylka, Xinzhong Dong & David J Anderson
Nature Neuroscience 10, 946–948
(August 2007); doi:10.1038/nn1937
| Summary | Full Text (HTML / PDF) |
letter
A gastrin-releasing peptide receptor mediates the itch sensation in the spinal cord
Yan-Gang Sun & Zhou-Feng Chen
Nature 448, 700–703
(9 August 2007); doi:10.1038/nature06029
| Summary | Full Text (HTML / PDF) |
July
letter
Functional diversification of closely related ARF-GEFs in protein secretion and recycling
Sandra Richter, Niko Geldner, Jarmo Schrader, Hanno Wolters, York-Dieter Stierhof, Gabino Rios, Csaba Koncz, David G. Robinson & Gerd Jürgens
Nature 448, 488–492
(26 July 2007); doi:10.1038/nature05967
| Summary | Full Text (HTML / PDF) |
letter
An ARF-GEF acting at the Golgi and in selective endocytosis in polarized plant cells
Ooi-kock Teh & Ian Moore
Nature 448, 493–496
(26 July 2007); doi:10.1038/nature06023
| Summary | Full Text (HTML / PDF) |
letter
The Rab8 GTPase regulates apical protein localization in intestinal cells
Takashi Sato, Sotaro Mushiake, Yukio Kato, Ken Sato, Miyuki Sato, Naoki Takeda, Keiichi Ozono, Kazunori Miki, Yoshiyuki Kubo, Akira Tsuji, Reiko Harada & Akihiro Harada
Nature 448, 366–369
(19 July 2007); doi:10.1038/nature05929
| Summary | Full Text (HTML / PDF) |
news and views
Cell biology: Caught in the traffic
Aparna Lakkaraju & Enrique Rodriguez-Boulan
Nature 448, 266–267
(19 July 2007); doi:10.1038/448266a
| Full Text (HTML / PDF) |
article
Regulation of T-type calcium channels by Rho-associated kinase
Mircea Iftinca, Jawed Hamid, Lina Chen, Diego Varela, Reza Tadayonnejad, Christophe Altier, Ray W Turner & Gerald W Zamponi
Nature Neuroscience 10, 854–860
(July 2007); doi:10.1038/nn1921
| Summary | Full Text (HTML / PDF) |
review
Post-translational modifications and regulation of the RAS superfamily of GTPases as anticancer targets
Panagiotis A. Konstantinopoulos, Michalis V. Karamouzis & Athanasios G. Papavassiliou
Nature Reviews Drug Discovery 6, 541–555
(July 2007); doi:10.1038/nrd2221
| Summary | Full Text (HTML / PDF) |
letter
Extension of Drosophila melanogaster life span with a GPCR peptide inhibitor
William W Ja, Anthony P West, Jr, Silvia L Delker, Pamela J Bjorkman, Seymour Benzer & Richard W Roberts
Nature Chemical Biology 3, 415–419
(July 2007); doi:10.1038/nchembio.2007.2
| Summary | Full Text (HTML / PDF) |
news and views
Methuselah antagonist extends life span
Deirdre McGarrigle & Xin-Yun Huang
Nature Chemical Biology 3, 371–372
(July 2007); doi:10.1038/nchembio0707-371
| Full Text (HTML / PDF) |
June
article
Activation of the lectin DC-SIGN induces an immature dendritic cell phenotype triggering Rho-GTPase activity required for HIV-1 replication
Ashleigh Hodges, Katherine Sharrocks, Mariola Edelmann, Dilair Baban, Arnaud Moris, Olivier Schwartz, Hal Drakesmith, Kay Davies, Benedikt Kessler, Andrew McMichael & Alison Simmons
Nature Immunology 8, 569–577
(June 2007); doi:10.1038/ni1470
| Summary | Full Text (HTML / PDF) |
news and views
DC-SIGN 'AIDS' HIV immune evasion and infection
Anthony L Cunningham, Andrew N Harman & Heather Donaghy
Nature Immunology 8, 556–558
(June 2007); doi:10.1038/ni0607-556
| Summary | Full Text (HTML / PDF) |
scientific report
Structural insights into a new homodimeric self-activated GTPase family
Stéphanie Gras, Valérie Chaumont, Bernard Fernandez, Philippe Carpentier, Fabienne Charrier-Savournin, Sophie Schmitt, Charles Pineau, Didier Flament, Arnaud Hecker, Patrick Forterre, Jean Armengaud & Dominique Housset
EMBO Reports 8, 569–575
(June 2007); doi:10.1038/sj.embor.7400958
| Summary | Full Text (HTML / PDF) |
letter
Chemical sensing of DNT by engineered olfactory yeast strain
Venkat Radhika, Tassula Proikas-Cezanne, Muralidharan Jayaraman, Djamila Onesime, Ji Hee Ha & Danny N Dhanasekaran
Nature Chemical Biology 3, 325–330
(June 2007); doi:10.1038/nchembio882
| Summary | Full Text (HTML / PDF) |
news and views
Smells like bread
David R Walt
Nature Chemical Biology 3, 306–307
(June 2007); doi:10.1038/nchembio0607-306
| Full Text (HTML / PDF) |
brief communication
Restoration of cone vision in a mouse model of achromatopsia
John J Alexander, Yumiko Umino, Drew Everhart, Bo Chang, Seok H Min, Qiuhong Li, Adrian M Timmers, Norman L Hawes, Ji-jing Pang, Robert B Barlow & William W Hauswirth
Nature Medicine 13, 685–687
(June 2007); doi:10.1038/nm1596
| Summary | Full Text (HTML / PDF) |
letter
Rewiring cellular morphology pathways with synthetic guanine nucleotide exchange factors
Brian J. Yeh, Robert J. Rutigliano, Anrica Deb, Dafna Bar-Sagi & Wendell A. Lim
Nature 447, 596–600
(31 May 2007); doi:10.1038/nature05851
| Summary | Full Text (HTML / PDF) |
scientific report
Structural insights into a new homodimeric self-activated GTPase family
Stéphanie Gras, Valérie Chaumont, Bernard Fernandez, Philippe Carpentier, Fabienne Charrier-Savournin, Sophie Schmitt, Charles Pineau, Didier Flament, Arnaud Hecker, Patrick Forterre, Jean Armengaud & Dominique Housset
EMBO Reports 8, 569–575
(June 2007); doi:10.1038/sj.embor.7400958
| Summary | Full Text (HTML / PDF) |
May
scientific report
Cyclic AMP signalling in Dictyostelium: G-proteins activate separate Ras pathways using specific RasGEFs
Helmut Kae, Arjan Kortholt, Holger Rehmann, Robert H Insall, Peter J M Van Haastert, George B Spiegelman & Gerald Weeks
EMBO Reports 8, 477–482
(May 2007); doi:10.1038/sj.embor.7400936
| Summary | Full Text (HTML / PDF) |
article
MIF is a noncognate ligand of CXC chemokine receptors in inflammatory and atherogenic cell recruitment
Jürgen Bernhagen, Regina Krohn, Hongqi Lue, Julia L Gregory, Alma Zernecke, Rory R Koenen, Manfred Dewor, Ivan Georgiev, Andreas Schober, Lin Leng, Teake Kooistra, Günter Fingerle-Rowson, Pietro Ghezzi, Robert Kleemann, Shaun R McColl, Richard Bucala, Michael J Hickey & Christian Weber
Nature Medicine 13, 587–596
(May 2007); doi:10.1038/nm1567
| Summary | Full Text (HTML / PDF) |
April
review
Antagonism of the prostaglandin D2 receptors DP1 and CRTH2 as an approach to treat allergic diseases
Roy Pettipher, Trevor T. Hansel & Richard Armer
Nature Reviews Drug Discovery 6, 313–325
(April 2007); doi:10.1038/nrd2266
| Summary | Full Text (HTML / PDF) |
March
review
Molecular mechanism of the nuclear protein import cycle
Murray Stewart
Nature Reviews Molecular Cell Biology 8, 195–208
(March 2007); doi:10.1038/nrm2114
| Summary | Full Text (HTML / PDF) |
article
Grb4 and GIT1 transduce ephrinB reverse signals modulating spine morphogenesis and synapse formation
Inmaculada Segura, Clara L Essmann, Stefan Weinges & Amparo Acker-Palmer
Nature Neuroscience 10, 301–310
(March 2007); doi:10.1038/nn1858
| Summary | Full Text (HTML / PDF) |
article
Adrenal GRK2 upregulation mediates sympathetic overdrive in heart failure
Anastasios Lymperopoulos, Giuseppe Rengo, Hajime Funakoshi, Andrea D Eckhart & Walter J Koch
Nature Medicine 13, 315–323
(March 2007); doi:10.1038/nm1553
| Summary | Full Text (HTML / PDF) |
news and views
Long-distance affair with adrenal GRK2 hangs up heart failure
Stephen B Liggett
Nature Medicine 13, 246–248
(March 2007); doi:10.1038/nm0307-246
| Summary | Full Text (HTML / PDF) |
article
Alternative splicing controls G protein—dependent inhibition of N-type calcium channels in nociceptors
Jesica Raingo, Andrew J Castiglioni & Diane Lipscombe
Nature Neurobiology 10, 285–292
(March 2007); doi:10.1038/nn1848
| Summary | Full Text (HTML / PDF) |
news and views
Calcium channels diversify their signaling portfolio
Stephen R Ikeda & Kathleen Dunlap
Nature Neurobiology 10, 269–271
(March 2007); doi:10.1038/nn0307-269
| Summary | Full Text (HTML / PDF) |
letter
C5L2 is critical for the biological activities of the anaphylatoxins C5a and C3a
Nien-Jung Chen, Christine Mirtsos, Daniel Suh, Yong-Chen Lu, Wen-Jye Lin, Colin McKerlie, Taeweon Lee, Helene Baribault, Hui Tian and Wen-Chen Yeh
Nature 446, 203–207
(8 March 2007); doi:10.1038/nature05559
| Summary | Full Text (HTML / PDF) |
February
letter
Drosophila TCTP is essential for growth and proliferation through regulation of dRheb GTPase
Ya-Chieh Hsu, Joshua J. Chern, Yi Cai, Mingyao Liu and Kwang-Wook Choi
Nature 445, 785–788
(15 February 2007); doi:10.1038/nature05528
| First Paragraph | Full Text (HTML / PDF) |
review
G-protein-coupled receptors and cancer
Robert T. Dorsam and J. Silvio Gutkind
Nature Reviews Cancer 7, 79–94
(February 2007); doi:10.1038/nrc2069
| Summary | Full Text (HTML / PDF) |
article
Rapid identification of functionally critical amino acids in a G protein-coupled receptor
Bo Li, Marco Scarselli, Christopher D Knudsen, Soo-Kyung Kim, Kenneth A Jacobson, Sara M McMillin & Jürgen Wess
Nature Methods 4, 169–174
(February 2007); doi:10.1038/nmeth990
| Summary | Full Text (HTML / PDF) |
January
brief communication
Sensitive and specific method for detecting G protein-coupled receptor mRNAs
Arne Hansen, Yidong Chen, Jason M Inman, Quang N Phan, Zhi-Qing Qi, Charlie C Xiang, Miklos Palkovits, Natasha Cherman, Sergei A Kuznetsov, Pamela G Robey, Eva Mezey & Michael J Brownstein
Nature Methods 4, 35–37
(January 2007); doi:10.1038/nmeth977
| Summary | Full Text (HTML / PDF) |
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