Research library: G-protein/GPCR signaling
2009:
| December
| November
| October
| September
| August
| June
| May
| April
| March
| February
| January
Other Years: 2002 | 2003 | 2004 | 2005 | 2006 | 2007 | 2008
December
letter
Regulation of a Golgi flippase by phosphoinositides and an ArfGEF
Paramasivam Natarajan et al.
Nature Cell Biology 11, 1421–1426
(December 2009); doi:10.1038/ncb1989
| Summary | Full Text (HTML / PDF) |
review
Fine-tuning of GPCR activity by receptor-interacting proteins
Stefanie L. Ritter & Randy A. Hall
Nature Reviews Molecular Cell Biology 10, 819–830
(December 2009); doi:10.1038/nrm2803
| Summary | Full Text (HTML / PDF) |
article
Dock8 mutations cripple B cell immunological synapses, germinal centers and long-lived antibody production
Katrina L Randall et al.
Nature Immunology 10, 1283–1291
(December 2009); doi:10.1038/ni.1820
| Summary | Full Text (HTML / PDF) |
news and views
B cell memory: how to start and when to end
Nadege Pelletier & Michael G McHeyzer-Williams
Nature Immunology 10, 1233–1235
(December 2009); doi:10.1038/ni1209-1233
| Full Text (HTML / PDF) |
November
letter
Slit2–Robo4 signalling promotes vascular stability by blocking Arf6 activity
Christopher A. Jones et al.
Nature Cell Biology 11, 1325–1331
(2009) doi:10.1038/ncb1976
| Summary | Full Text (HTML / PDF) |
article
The oligodendrocyte-specific G protein–coupled receptor GPR17 is a cell-intrinsic timer of myelination
Ying Chen et al.
Nature Neuroscience 12, 1398–1406
(November 2009); doi:10.1038/nn.2410
| Summary | Full Text (HTML / PDF) |
article
CARD9 facilitates microbe-elicited production of reactive oxygen species by regulating the LyGDI-Rac1 complex
Weihui Wu, Yen-Michael S Hsu, Liangkuan Bi, Zhou Songyang & Xin Lin
Nature Immunology 10, 1208–1214
(November 2009); doi:10.1038/ni.1788
| Summary | Full Text (HTML / PDF) |
October
letter
Regulation of inflammatory responses by gut microbiota and chemoattractant receptor GPR43
Kendle M. Maslowski et al.
Nature 461, 1282–1286
(29 October 2009); doi:10.1038/nature08530
| Full Text (HTML / PDF) |
letter
Spatiotemporal control of cell signalling using a light-switchable protein interaction
Anselm Levskaya, Orion D. Weiner, Wendell A. Lim & Christopher A. Voigt
Nature 461, 997–1001
(15 October 2009); doi:10.1038/nature08446
| Full Text (HTML / PDF) |
article
Ras orchestrates exit from the cell cycle and light-chain recombination during early B cell development
Malay Mandal et al.
Nature Immunology 10, 1110–1117
(October 2009); doi:10.1038/ni.1785
| Summary | Full Text (HTML / PDF) |
letter
Gene therapy for red–green colour blindness in adult primates
Katherine Mancuso et al.
Nature 461, 784–787
(08 October 2009); doi:10.1038/nature08401
| Full Text (HTML / PDF) |
news and views
Vision: Gene therapy in colour
Robert Shapley
Nature 461, 737–739
(08 October 2009); doi:10.1038/461737a
| Full Text (HTML / PDF) |
article
Epac2 induces synapse remodeling and depression and its disease-associated forms alter spines
Kevin M Woolfrey et al.
Nature Neuroscience 12, 1275–1284
(October 2009); doi:10.1038/nn.2386
| Summary | Full Text (HTML / PDF) |
article
A new glucagon and GLP-1 co-agonist eliminates obesity in rodents
Jonathan W Day et al.
Nature Chemical Biology 5, 749–757
(October 2009); doi:10.1038/nchembio.209
| Summary | Full Text (HTML / PDF) |
article
Sustained cyclic AMP production by parathyroid hormone receptor endocytosis
Sébastien Ferrandon et al.
Nature Chemical Biology 5, 734–742
(October 2009); doi:10.1038/nchembio.206
| Summary | Full Text (HTML / PDF) |
news and views
When two keys fit one lock, surprises follow
Michael Rosenblatt
Nature Chemical Biology 5, 707–708
(October 2009); doi:10.1038/nchembio.225
| Full Text (HTML / PDF) |
September
letter
Integration of neuronal clones in the radial cortical columns by EphA and ephrin-A signalling
Masaaki Torii, Kazue Hashimoto-Torii, Pat Levitt & Pasko Rakic
Nature 461, 524–528
(24 September 2009); doi:10.1038/nature08362
| Full Text (HTML / PDF) |
letter
Mutation of SHOC2 promotes aberrant protein N-myristoylation and causes Noonan-like syndrome with loose anagen hair
Viviana Cordeddu et al.
Nature Genetics 41, 1022–1026
(September 2009); doi:10.1038/ng.425
| Summary | Full Text (HTML / PDF) |
review
Endocytosis and signalling: intertwining molecular networks
Alexander Sorkin & Mark von Zastrow
Nature Reviews Molecular Cell Biology 10, 609–622
(September 2009); doi:10.1038/nrm2748
| Summary | Full Text (HTML / PDF) |
review
Rho family GTPases and their regulators in lymphocytes
Victor L. J. Tybulewicz & Robert B. Henderson
Nature Reviews Immunology 9, 630–644
(September 2009); doi:10.1038/nri2606
| Summary | Full Text (HTML / PDF) |
article
Allosteric communication between protomers of dopamine class A GPCR dimers modulates activation
Yang Han, Irina S Moreira, Eneko Urizar, Harel Weinstein & Jonathan A Javitch
Nature Chemical Biology 5, 688–695
(September 2009); doi:10.1038/nchembio.199
| Summary | Full Text (HTML / PDF) |
news and views
A division of labor: asymmetric roles for GPCR subunits in receptor dimers
Peter Zylbergold & Terence E Hébert
Nature Chemical Biology 5, 608–609
(September 2009); doi:10.1038/nchembio0909-608
| Full Text (HTML / PDF) |
letter
Coordination of Rho GTPase activities during cell protrusion
Matthias Machacek et al.
Nature 461, 99–103
(03 September 2009); doi:10.1038/nature08242
| Full Text (HTML / PDF) |
letter
A genetically encoded photoactivatable Rac controls the motility of living cells
Yi I. Wu et al.
Nature 461, 104–108
(03 September 2009); doi:10.1038/nature08241
| Full Text (HTML / PDF) |
August
article
A discrete alcohol pocket involved in GIRK channel activation
Prafulla Aryal, Hay Dvir, Senyon Choe & Paul A Slesinger
Nature Neuroscience 12, 988–995
(August 2009); doi:10.1038/nn.2358
| Summary | Full Text (HTML / PDF) |
letter
Neurotransmission selectively regulates synapse formation in parallel circuits in vivo
Daniel Kerschensteiner, Josh L. Morgan, Edward D. Parker, Renate M. Lewis & Rachel O. L. Wong
Nature 460, 1016–1020
(20 August 2009); doi:10.1038/nature08236
| Full Text (HTML / PDF) |
news and views
Neuroscience: Activity acts locally
Jonathan B. Demb & Marla B. Feller
Nature 460, 961–963
(20 August 2009); doi:10.1038/460961a
| Full Text (HTML / PDF) |
article
Structural and functional studies of the Ras-associating and pleckstrin-homology domains of Grb10 and Grb14
Rafael S Depetris, Jinhua Wu & Stevan R Hubbard
Nature Structural & Molecular Biology 16, 833–839
(August 2009); doi:10.1038/nsmb.1642
| Summary | Full Text (HTML / PDF) |
news and views
Grb-ing hold of insulin signaling
Derek F J Ceccarelli & Frank Sicheri
Nature Structural & Molecular Biology 16, 803–804
(August 2009); doi:10.1038/nsmb0809-803
| Full Text (HTML / PDF) |
article
Structural insights into host GTPase isoform selection by a family of bacterial GEF mimics
Zhiwei Huang et al.
Nature Structural & Molecular Biology 16, 853–860
(August 2009); doi:10.1038/nsmb.1647
| Summary | Full Text (HTML / PDF) |
article
Essential function for the GTPase TC21 in homeostatic antigen receptor signaling
Pilar Delgado et al.
Nature Immunology 10, 880–888
(August 2009); doi:10.1038/ni.1749
| Summary | Full Text (HTML / PDF) |
perspective
Cellular assays as portals to seven-transmembrane receptor-based drug discovery
Terry P. Kenakin
Nature Reviews Drug Discovery 8, 617–626
(August 2009); doi:10.1038/nrd2838
| Summary | Full Text (HTML / PDF) |
review
Rab GTPases as coordinators of vesicle traffic
Harald Stenmark
Nature Reviews Molecular Cell Biology 10, 513–525
(August 2009); doi:10.1038/nrm2728
| Summary | Full Text (HTML / PDF) |
review
Random versus directionally persistent cell migration
Ryan J. Petrie, Andrew D. Doyle & Kenneth M. Yamada
Nature Reviews Molecular Cell Biology 10, 538–549
(August 2009); doi:10.1038/nrm2729
| Summary | Full Text (HTML / PDF) |
June
perspective
It takes two to tango: regulation of G proteins by dimerization
Raphael Gasper, Simon Meyer, Katja Gotthardt, Minhajuddin Sirajuddin & Alfred Wittinghofer
Nature Reviews Molecular Cell Biology 10, 423–429
(June 2009); doi:10.1038/nrm2689
| Summary | Full Text (HTML / PDF) |
brief communication
FTIR analysis of GPCR activation using azido probes
Shixin Ye, Thomas Huber, Reiner Vogel & Thomas P Sakmar
Nature Chemical Biology 5, 397–399
(June 2009); doi:10.1038/nchembio.167
| Summary | Full Text (HTML / PDF) |
article
Lfc and Tctex-1 regulate the genesis of neurons from cortical precursor cells
Andrée Gauthier-Fisher et al.
Nature Neuroscience 12, 735–744
(June 2009); doi:10.1038/nn.2339
| Summary | Full Text (HTML / PDF) |
news and views
Neurogenesis in G minor
Anne-Marie Marzesco, Felipe Mora-Bermudez & Wieland B Huttner
Nature Neuroscience 12, 669–671
(June 2009); doi:10.1038/nn0609-669
| Full Text (HTML / PDF) |
article
In vivo effects of a GPR30 antagonist
Megan K Dennis et al.
Nature Chemical Biology 5, 421–427
(June 2009); doi:10.1038/nchembio.168
| Summary | Full Text (HTML / PDF) |
analysis
Community-wide assessment of GPCR structure modelling and ligand docking: GPCR Dock 2008
Mayako Michino et al.
Nature Reviews Drug Discovery 8, 455–463
(June 2009); doi:10.1038/nrd2877
| Summary | Full Text (HTML / PDF) |
May
letter
Formyl peptide receptor-like proteins are a novel family of vomeronasal chemosensors
Stéphane Rivière, Ludivine Challet, Daniela Fluegge, Marc Spehr & Ivan Rodriguez
Nature 459, 574–577
(28 May 2009); doi:10.1038/nature08029
| Full Text (HTML / PDF) |
letter
Bone morphogenetic protein heterodimers assemble heteromeric type I receptor complexes to pattern the dorsoventral axis
Shawn C. Little & Mary C. Mullins
Nature Cell Biology 11, 637–643
(May 2009); doi:10.1038/ncb1870
| Summary | Full Text (HTML / PDF) |
perspective
The evolving understanding of COPI vesicle formation
Victor W. Hsu, Stella Y. Lee & Jia-Shu Yang
Nature Reviews Molecular Cell Biology 10, 360–364
(May 2009); doi:10.1038/nrm2663
| Summary | Full Text (HTML / PDF) |
review
Islet G protein-coupled receptors as potential targets for treatment of type 2 diabetes
Bo Ahrén
Nature Reviews Drug Discovery 8, 369–385
(May 2009); doi:10.1038/nrd2782
| Summary | Full Text (HTML / PDF) |
brief communication
Structural basis for assembly and disassembly of the CRM1 nuclear export complex
Xiuhua Dong, Anindita Biswas & Yuh Min Chook
Nature Structural & Molecular Biology 16, 558–560
(May 2009); doi:10.1038/nsmb.1586
| Summary | Full Text (HTML / PDF) |
news and views
Nuclear transport comes full circle
Erik W Debler, Günter Blobel & André Hoelz
Nature Structural & Molecular Biology 16, 457–459
(May 2009); doi:10.1038/nsmb0509-457
| Full Text (HTML / PDF) |
letter
Haematopoietic stem cells depend on Gαs-mediated signalling to engraft bone marrow
Gregor B. Adams et al.
Nature 459, 103–107
(07 May 2009); doi:10.1038/nature07859
| Full Text (HTML / PDF) |
perspective
Bringing up the rear: defining the roles of the uropod
Francisco Sánchez-Madrid & Juan M. Serrador
Nature Reviews Molecular Cell Biology 10, 353–359
(May 2009); doi:10.1038/nrm2680
| Summary | Full Text (HTML / PDF) |
April
letter
Temporally precise in vivo control of intracellular signalling
Raag D. Airan, Kimberly R. Thompson, Lief E. Fenno, Hannah Bernstein & Karl Deisseroth
Nature 458, 1025–1029
(23 April 2009); doi:10.1038/nature07926
| Summary | Full Text (HTML / PDF) |
news and views
Neuroscience: Optical control of reward
David E. Moorman & Gary Aston-Jones
Nature 458, 980–981
(23 April 2009); doi:10.1038/458980a
| Full Text (HTML / PDF) |
review
Capturing adenylyl cyclases as potential drug targets
Sandra Pierre, Thomas Eschenhagen, Gerd Geisslinger & Klaus Scholich
Nature Reviews Drug Discovery 8, 321–335
(April 2009); doi:10.1038/nrd2827
| Summary | Full Text (HTML / PDF) |
article
Analysis of the eukaryotic prenylome by isoprenoid affinity tagging
Uyen T T Nguyen et al.
Nature Chemical Biology 5, 227–235
(April 2009); doi:10.1038/nchembio.149
| Summary | Full Text (HTML / PDF) |
news and views
Getting a handle on protein prenylation
James L Hougland & Carol A Fierke
Nature Chemical Biology 5, 197–198
(April 2009); doi:10.1038/nchembio0409-197
| Full Text (HTML / PDF) |
review
Chemical modulators of sphingosine-1-phosphate receptors as barrier-oriented therapeutic molecules
David Marsolais & Hugh Rosen
Nature Reviews Drug Discovery 8, 297–307
(April 2009); doi:10.1038/nrd2356
| Summary | Full Text (HTML / PDF) |
March
letter
TAC3 and TACR3 mutations in familial hypogonadotropic hypogonadism reveal a key role for Neurokinin B in the central control of reproduction
A Kemal Topaloglu et al.
Nature Genetics 41, 354–358
(March 2009); doi:10.1038/ng.306
| Summary | Full Text (HTML / PDF) |
news and views
The neurokinin B pathway in human reproduction
Ana Claudia Latronico
Nature Genetics 41, 269–270
(March 2009); doi:10.1038/ng0309-269
| Full Text (HTML / PDF) |
article
Golgicide A reveals essential roles for GBF1 in Golgi assembly and function
José B Sáenz et al.
Nature Chemical Biology 5, 157–165
(March 2009); doi:10.1038/nchembio.144
| Summary | Full Text (HTML / PDF) |
February
article
A mechanosensitive transcriptional mechanism that controls angiogenesis
Akiko Mammoto et al.
Nature 457, 1103–1108
(26 February 2009); doi:10.1038/nature07765
| Summary | Full Text (HTML / PDF) |
article
Regulation of conformer-specific activation of the integrin LFA-1 by a chemokine-triggered Rho signaling module
Matteo Bolomini-Vittori et al.
Nature Immunology 10, 185–194
(February 2009); doi:10.1038/ni.1691
| Summary | Full Text (HTML / PDF) |
article
The cerebral cavernous malformation signaling pathway promotes vascular integrity via Rho GTPases
Kevin J Whitehead et al.
Nature Medicine 15, 177–184
(February 2009); doi:10.1038/nm.1911
| Summary | Full Text (HTML / PDF) |
letter
Peptide neurotransmitters activate a cation channel complex of NALCN and UNC-80
Boxun Lu et al.
Nature 457, 741–744
(05 February 2009); doi:10.1038/nature07579
| Summary | Full Text (HTML / PDF) |
January
letter
Frequent somatic mutations of GNAQ in uveal melanoma and blue naevi
Catherine D. Van Raamsdonk et al.
Nature 457, 599–602
(January 2009); doi:10.1038/nature07586
| Summary | Full Text (HTML / PDF) |
review
Allosteric modulators of GPCRs: a novel approach for the treatment of CNS disorders
P. Jeffrey Conn, Arthur Christopoulos & Craig W. Lindsley
Nature Reviews Drug Discovery 8, 41–54
(January 2009); doi:10.1038/nrd2760
| Summary | Full Text (HTML / PDF) |
letter
Regulation of cytokinesis by Rho GTPase flux
Ann L. Miller & William M. Bement
Nature Cell Biology 11, 71–77
(January 2009); doi:10.1038/ncb1814
| Summary | Full Text (HTML / PDF) |
article
A new type of ERK1/2 autophosphorylation causes cardiac hypertrophy
Kristina Lorenz, Joachim P Schmitt, Eva M Schmitteckert & Martin J Lohse
Nature Medicine 15, 75–83
(January 2009); doi:10.1038/nm.1893
| Summary | Full Text (HTML / PDF) |
article
Apoptotic histone modification inhibits nuclear transport by regulating RCC1
Chi-Hang Wong et al.
Nature Cell Biology 11, 36–45
(January 2009); doi:10.1038/ncb1810
| Summary | Full Text (HTML / PDF) |
news and views
Ran out of the nucleus for apoptosis
Andrew Wilde & Yixian Zheng
Nature Cell Biology 11, 11–12
(January 2009); doi:10.1038/ncb0109-11
| Full Text (HTML / PDF) |
|
