news and views Apoptosis: eating sensibly
Christopher D. Gregory and Simon B. Brown Nature Cell Biology7, 1161–1163
(December 2005); doi:10.1038/ncb1205-1061
| | Full Text (HTML/PDF) |
article A promiscuous liaison between IL-15 receptor and Axl receptor tyrosine kinase in cell death control
Vadim Budagian, Elena Bulanova, Zane Orinska, Lutz Thon, Uwe Mamat1, Paola Bellosta, Claudio Basilico, Dieter Adam, Ralf Paus and Silvia Bulfone-Paus The EMBO Journal24, 4260–4270
(December 2005); doi:10.1038/sj.emboj.7600874
| First Paragraph | Full Text (HTML/PDF) |
article The peptidyl-prolyl isomerase Pin1 regulates the stability of granulocyte-macrophage colony-stimulating factor mRNA in activated eosinophils
Zhong-Jian Shen, Stephane Esnault and James S Malter Nature Immunology6, 1280–1287
(December 2005); doi:10.1038/ni1266
| Abstract | Full Text (HTML/PDF) |
news and views Pin1: a proline isomerase that makes you wheeze?
Paul Anderson Nature Immunology6, 1211–1212
(December 2005); doi:10.1038/ni1205-1211
| Full Text (HTML/PDF) |
November
review article Lysosomes and autophagy in cell death control
Guido Kroemer and Marja Jäättelä Nature Reviews Cancer5, 886–897
(November 2005); doi:10.1038/nrc1738
| Summary | Full Text (HTML / PDF) |
news and views Autophagy: to die or not to die
Myrto Raftopoulou Nature Cell Biology7, 1056
(November 2005); doi:10.1038/ncb1105-1056
| Full Text (HTML/PDF) |
article Regulation of lung injury and repair by Toll-like receptors and hyaluronan
Dianhua Jiang, Jiurong Liang, Juan Fan, Shuang Yu, Suping Chen, Yi Luo, Glenn D Prestwich, Marcella M Mascarenhas, Hari G Garg, Deborah A Quinn, Robert J Homer, Daniel R Goldstein, Richard Bucala, Patty J Lee, Ruslan Medzhitov and Paul W Noble Nature Medicine11, 1173–1179
(November 2005); doi:10.1038/nm1315
| Abstract | Full Text (HTML/PDF) |
news and views TLRs play good cop, bad cop in the lung
Luke A J O'Neill Nature Medicine11, 1161–1162
(November 2005); doi:10.1038/nm1105-1161
| Full Text (HTML/PDF) |
review article Promoting apoptosis as a strategy for cancer drug discovery
Stephen W. Fesik Nature Reviews Cancer5, 876–885
(November 2005); doi:10.1038/nrc1736
| Summary | Full Text (HTML / PDF) |
article CCL5-CCR5 interaction provides antiapoptotic signals for macrophage survival during viral infection
Jeffrey W Tyner, Osamu Uchida, Naohiro Kajiwara, Edy Y Kim, Anand C Patel, Mary P O'Sullivan, Michael J Walter, Reto A Schwendener, Donald N Cook, Theodore M Danoff and Michael J Holtzman Nature Medicine11, 1080–1087
(November 2005); doi:10.1038/nm1303
| Abstract
| Full Text (HTML / PDF) |
October
news and views Cell biology: A BID for the pathway
Michael B. Kastan Nature437, 1103
(20 October 2005); doi:10.1038/4371103a
| Full Text (HTML / PDF) |
article Apoptosis induced by vitamin A signaling is crucial for connecting the ureters to the bladder
Ekatherina Batourina, Sheaumei Tsai, Sarah Lambert, Preston Sprenkle, Renata Viana, Sonia Dutta, Terry Hensle, Fengwei Wang, Karen Niederreither, Andrew P McMahon, Thomas J Carroll and Cathy L Mendelsohn Nature Genetics37, 1082–1089
(October 2005); doi:10.1038/ng1645
| Abstract | Full Text (HTML/PDF) |
article Structure of the CED-4-CED-9 complex provides insights into programmed cell death in Caenorhabditis elegans
Nieng Yan, Jijie Chai, Eui Seung Lee, Lichuan Gu, Qun Liu, Jiaqing He, Jia-Wei Wu, David Kokel, Huilin Li, Quan Hao, Ding Xue and Yigong Shi Nature437, 831–837
(06 October 2005); doi:10.1038/nature04002
| Abstract | Full Text (HTML / PDF) |
letter The endoplasmic reticulum gateway to apoptosis by Bcl-XL modulation of the InsP3R
Carl White, Chi Li, Jun Yang, Nataliya B. Petrenko, Muniswamy Madesh, Craig B. Thompson and J. Kevin Foskett Nature Cell Biology7, 1021–1028
(October 2005); doi:10.1038/ncb1302
| First Paragraph | Full Text (HTML/PDF) |
article Caspase-specific and nonspecific in vivo protein processing during Fas-induced apoptosis
Petra Van Damme, Lennart Martens, Jozef Van Damme, Koen Hugelier, An Staes, Joël Vandekerckhove and Kris Gevaert Nature Methods2, 771–777
(October 2005); doi:10.1038/nmeth792
| Abstract | Full Text (HTML/PDF) |
September
letter Accelerated ageing in mice deficient in Zmpste24 protease is linked to p53 signalling activation
Ignacio Varela, Juan Cadiñanos, Alberto M. Pendás, Ana Gutiérrez-Fernández, Alicia R. Folgueras, Luis M. Sánchez, Zhongjun Zhou, Francisco J. Rodríguez, Colin L. Stewart, José A Vega, Karl Tryggvason, José M. P. Freije and Carlos López-Otín Nature437, 564–568
(22 September 2005); doi:10.1038/nature04019
| First Paragraph | Full Text (HTML / PDF) |
letter Clusterin inhibits apoptosis by interacting with activated Bax
Honglai Zhang, Jin Koo Kim, Chris A. Edwards, Zhaohui Xu, Russell Taichman and Cun-Yu Wang Nature Cell Biology7, 909–915
(September 2005); doi:10.1038/ncb1291
| First Paragraph | Full Text (HTML/PDF) |
letter WNT7b mediates macrophage-induced programmed cell death in patterning of the vasculature
Ivan B. Lobov, Sujata Rao, Thomas J. Carroll, Jefferson E. Vallance, Masataka Ito, Jennifer K. Ondr, Savita Kurup, Donald A. Glass, Millan S. Patel, Weiguo Shu, Edward E. Morrisey, Andrew P. McMahon, Gerard Karsenty and Richard A. Lang Nature437, 417–421
(15 September 2005); doi:10.1038/nature03928
| First Paragraph | Full Text (HTML / PDF) |
review article Interleukin-21: a modulator of lymphoid proliferation, apoptosis and differentiation
Warren J. Leonard and Rosanne Spolski Nature Reviews Immunology5, 688–698
(September 2005); doi:10.1038/nri1688
| Abstract | Full Text (HTML / PDF) |
article Bag1 is essential for differentiation and survival of hematopoietic and neuronal cells
Rudolf Götz, Stefan Wiese, Shinichi Takayama, Guadalupe C Camarero, Wilfried Rossoll, Ulrich Schweizer, Jakob Troppmair, Sibylle Jablonka, Bettina Holtmann, John C Reed, Ulf R Rapp and Michael Sendtner Nature Neuroscience8, 1169–1178
(September 2005); doi:10.1038/nn1524
| Abstract | Full Text (HTML/PDF) |
review article Trashing the genome: the role of nucleases during apoptosis
Kumiko Samejima and William C. Earnshaw Nature Reviews Molecular Cell Biology6, 677–688
(September 2005); doi:10.1038/nrm1715
| Abstract | Full Text (HTML / PDF) |
August
article Membrane phosphatidylserine distribution as a non-apoptotic signalling mechanism in lymphocytes
James I. Elliott, Annmarie Surprenant, Federica M. Marelli-Berg, Joanne C. Cooper, Robin L. Cassady-Cain, Carol Wooding, Kenneth Linton, Denis R. Alexander and Christopher F. Higgins Nature Cell Biology7, 808–816
(August 2005); doi:10.1038/ncb1279
| Abstract | Full Text (HTML/PDF) |
letter Intracellular protein therapy with SOCS3 inhibits inflammation and apoptosis
Daewoong Jo, Danya Liu, Shan Yao, Robert D Collins and Jacek Hawiger Nature Medicine11, 892–898
(August 2005); doi:10.1038/nm1269
| First Paragraph | Full Text (HTML/PDF) |
article Evasion of the p53 tumour surveillance network by tumour-derived MYC mutants
Michael T. Hemann, Anka Bric, Julie Teruya-Feldstein, Andreas Herbst, Jonas A. Nilsson, Carlos Cordon-Cardo, John L. Cleveland, William P. Tansey and Scott W. Lowe Nature436, 807–811
(11 August 2005); doi:10.1038/nature03845
| Abstract | Full Text (HTML / PDF) |
news and views Cancer: Two in one
Anton Berns Nature436, 787–789
(11 August 2005); doi:10.1038/436787a
| Full Text (HTML / PDF) |
review article Regulation of immune responses by L-arginine metabolism
Vincenzo Bronte and Paola Zanovello Nature Reviews Immunology5, 641–654
(August 2005); doi:10.1038/nri1668
| Abstract | Full Text (HTML / PDF) |
review article Telomeres and human disease: ageing, cancer and beyond
Maria A. Blasco Nature Reviews Genetics6, 611–622
(August 2005); doi:10.1038/nrg1656
| Abstract | Full Text (HTML / PDF) |
article Oncogene-induced senescence as an initial barrier in lymphoma development
Melanie Braig, Soyoung Lee, Christoph Loddenkemper, Cornelia Rudolph, Antoine H.F.M. Peters, Brigitte Schlegelberger, Harald Stein, Bernd Dörken, Thomas Jenuwein and Clemens A. Schmitt Nature436, 660–665
(04 August 2005); doi:10.1038/nature03841
| Abstract | Full Text (HTML / PDF) |
letter Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis
Zhenbang Chen, Lloyd C. Trotman, David Shaffer, Hui-Kuan Lin, Zohar A. Dotan, Masaru Niki, Jason A. Koutcher, Howard I. Scher, Thomas Ludwig, William Gerald, Carlos Cordon-Cardo and Pier Paolo Pandolfi Nature436, 725–730
(04 August 2005); doi:10.1038/nature03918
| First Paragraph | Full Text (HTML / PDF) |
letter BRAFE600-associated senescence-like cell cycle arrest of human naevi
Chrysiis Michaloglou, Liesbeth C. W. Vredeveld, Maria S. Soengas, Christophe Denoyelle, Thomas Kuilman, Chantal M. A. M. van der Horst, Donné M. Majoor, Jerry W. Shay, Wolter J. Mooi and Daniel S. Peeper Nature436, 720–724
(04 August 2005); doi:10.1038/nature03890
| First Paragraph | Full Text (HTML / PDF) |
brief communications Tumour biology: Senescence in premalignant tumours
Manuel Collado, Jesús Gil, Alejo Efeyan, Carmen Guerra, Alberto J. Schuhmacher, Marta Barradas, Alberto Benguría, Angel Zaballos, Juana M. Flores, Mariano Barbacid, David Beach and Manuel Serrano Nature436, 642
(04 August 2005); doi:10.1038/436642a
| First Paragraph | Full Text (HTML / PDF) |
news and views Cancer: Crime and punishment
Norman E. Sharpless and Ronald A. DePinho Nature436, 636–637
(04 August 2005); doi:10.1038/436636a
| Full Text (HTML / PDF) |
July
article S-nitrosylated
GAPDH initiates apoptotic cell death by nuclear translocation following Siah1
binding Makoto R. Hara, Nishant Agrawal, Sangwon F. Kim, Matthew B.
Cascio, Masahiro Fujimuro, Yuji Ozeki, Masaaki Takahashi, Jaime H. Cheah,
Stephanie K. Tankou, Lynda D. Hester, Christopher D. Ferris, S. Diane Hayward,
Solomon H. Snyder and Akira Sawa Nature Cell Biology7,
665–674 (July 2005); doi:10.1038/ncb1268 | Abstract | Full Text (HTML/PDF)
|
news and views A central role
for S-nitrosylation in apoptosis Moran Benhar and Jonathan S.
Stamler Nature Cell Biology7, 645–646 (July 2005);
doi:10.1038/ncb0705-645 | Full Text
(HTML/PDF) |
review
article Caspase-independent cell death Guido Kroemer and
Seamus J Martin Nature Medicine11, 725–730 (July 2005);
doi:10.1038/nm1263 | Abstract | Full Text (HTML/PDF)
|
June
letter Ephrin signalling controls brain size by regulating apoptosis of neural progenitors
Vanessa Depaepe, Nathalie Suarez-Gonzalez, Audrey Dufour, Lara Passante, Jessica A Gorski, Kevin R. Jones, Catherine Ledent and Pierre Vanderhaeghen Nature435, 1244–1250
(30 June 2005); doi:10.1038/nature03651
| First Paragraph | Full Text (HTML/PDF) |
letter Inflammatory arthritis requires Foxo3a to prevent Fas ligand-induced neutrophil apoptosis
Helena Jonsson, Paul Allen and Stanford L Peng Nature Medicine11, 666–671
(June 2005); doi:10.1038/nm1248
| First Paragraph | Full Text (HTML/PDF) |
news and views A fork in the pathway to inflammation and arthritis
Foo Y Liew and Iain B McInnes Nature Medicine11, 601–602
(June 2005); doi:10.1038/nm0605-601
| Full Text (HTML/PDF) |
letter An inhibitor of Bcl-2 family proteins induces regression of solid tumours
Tilman Oltersdorf , Steven W. Elmore , Alexander R. Shoemaker , Robert C. Armstrong , David J. Augeri , Barbara A. Belli , Milan Bruncko , Thomas L. Deckwerth , Jurgen Dinges , Philip J. Hajduk , Mary K. Joseph , Shinichi Kitada , Stanley J. Korsmeyer , Aaron R. Kunzer , Anthony Letai , Chi Li , Michael J. Mitten , David G. Nettesheim , ShiChung Ng , Paul M. Nimmer , Jacqueline M. O'Connor , Anatol Oleksijew , Andrew M. Petros , John C. Reed , Wang Shen , Stephen K. Tahir , Craig B. Thompson , Kevin J. Tomaselli , Baole Wang , Michael D. Wendt , Haichao Zhang , Stephen W. Fesik and Saul H. Rosenberg Nature435, 677–681
(02 June 2005); doi:10.1038/nature03579
| First Paragraph | Full Text (HTML / PDF) |
article Sensitized RNAi screen of human kinases and phosphatases identifies new regulators of apoptosis and chemoresistance
Jeffrey P. MacKeigan, Leon O. Murphy and John Blenis Nature Cell Biology7, 591–600
(June 2005); doi:10.1038/ncb1258
| Abstract | Full Text (HTML/PDF) |
May
review article Regulators of apoptosis: suitable targets for immune therapy of cancer
Mads Hald Andersen , Jürgen C. Becker and Per thor Straten Nature Reviews Drug Discovery4, 399–409
(May 2005); doi:10.1038/nrd1717
| Summary | Full Text (HTML / PDF) |
article Ceramide upregulation causes pulmonary cell apoptosis and emphysema-like disease in mice
Irina Petrache, Viswanathan Natarajan, Lijie Zhen, Terry R Medler, Amy T Richter, Chung Cho, Walter C Hubbard, Evgeny V Berdyshev and Rubin M Tuder Nature Medicine11, 491–498
(June 2005); doi:10.1038/nm1238
| Abstract | Full Text (HTML/PDF) |
news and views Lipid let loose in pulmonary emphysema
Jack A Elias and Chun Geun Lee Nature Medicine11, 471–472
(May 2005); doi:10.1038/nm0505-471
| Full Text (HTML/PDF) |
April
letters to nature Peak SIV replication in resting memory CD4+ T cells depletes gut lamina propria CD4+ T cells Qingsheng Li, Lijie Duan, Jacob D.Estes, Zhong-Min Ma, Tracy Rourke, Yichuan Wang, Cavan Reilly, John Carlis, Christopher J.Miller and Ashley T.Haase Nature434, 1148–1152
(28 April 2005); doi:10.1038/nature03513
| First Paragraph | Full Text (HTML / PDF) |
review article Nuclear factor-κB inhibitors as sensitizers to anticancer drugs
Chikashi Nakanishi and Masakazu Toi Nature Reviews Cancer5, 297–309
(April 2005); doi:10.1038/nrc1588
| Summary | Full Text (HTML / PDF) |
review article Translational control in stress and apoptosis
Martin Holcik and Nahum Sonenberg Nature Reviews Molecular Cell Biology6, 318–327
(April 2005); doi:10.1038/nrm1618
| Summary | Full Text (HTML / PDF) |
letters to nature Structure of the apoptotic protease-activating factor 1 bound to ADP
Stefan J. Riedl, Wenyu Li, Yang Chao, Robert Schwarzenbacher and Yigong Shi Nature434, 926–933
(14 April 2005); doi:10.1038/nature03465
| First Paragraph | Full Text (HTML / PDF) |
letter Stat3-induced apoptosis requires a molecular switch in PI(3)K subunit composition
Kathrine Abell, Antonio Bilancio, Richard W. E. Clarkson, Paul G. Tiffen, Anton I. Altaparmakov, Thomas G. Burdon, Tomoichiro Asano, Bart Vanhaesebroeck and Christine J. Watson Nature Cell Biology7, 392–398
(April 2005); doi:10.1038/ncb1242
| First Paragraph | Full Text (HTML/PDF) |
letters to nature Ipr1 gene mediates innate immunity to tuberculosis
Hui Pan, Bo-Shiun Yan, Mauricio Rojas , Yuriy V. Shebzukhov, Hongwei Zhou, Lester Kobzik, Darren E. Higgins, Mark J. Daly, Barry R. Bloom and Igor Kramnik Nature434, 767–772
(07 April 2005); doi:10.1038/nature03419
| First Paragraph | Full Text (HTML / PDF) |
news and views Tuberculosis: The genetics of vulnerability
Nada Jabado and Philippe Gros Nature434, 709–711
(07 April 2005); doi:10.1038/434709a
| Full Text (HTML / PDF) |
review article IAPs, RINGs and ubiquitylation
David L. Vaux and John Silke Nature Reviews Molecular Cell Biology6, 287–297
(April 2005); doi:10.1038/nrm1621
| Summary | Full Text (HTML / PDF) |
letters to nature Cyclophilin D-dependent mitochondrial permeability transition regulates some necrotic but not apoptotic cell death
Takashi Nakagawa , Shigeomi Shimizu, Tetsuya Watanabe, Osamu Yamaguchi, Kinya Otsu, Hirotaka Yamagata, Hidenori Inohara, Takeshi Kubo and Yoshihide Tsujimoto Nature434, 652–658
(31 March 2005); doi:10.1038/nature03317
| First Paragraph | Full Text (HTML / PDF) |
letters to nature Loss of cyclophilin D reveals a critical role for mitochondrial permeability transition in cell death
Christopher P. Baines, Robert A. Kaiser, Nicole H. Purcell, N. Scott Blair, Hanna Osinska, Michael A. Hambleton, Eric W. Brunskill, M. Richard Sayen, Roberta A. Gottlieb, Gerald W. Dorn II, Jeffrey Robbins and Jeffery D. Molkentin Nature434, 658–662
(31 March 2005); doi:10.1038/nature03434
| First Paragraph | Full Text (HTML / PDF) |
March
article Soluble CPG15 expressed during early development rescues cortical progenitors from apoptosis
Ulrich Putz, Corey Harwell and Elly Nedivi Nature Neuroscience8, 322–331
(March 2005); doi:10.1038/nn1407
| Abstract | Full Text (HTML/PDF) |
article Bcr-Abl-mediated suppression of normal hematopoiesis in leukemia
Randall E Burton, Tania A Baker and Robert T Sauer Oncogene
(AOP 28 February 2005); doi:10.1038/c
| Abstract | Full Text (HTML/PDF) |
letters to nature CD4+ T-cell help controls CD8+ T-cell memory via TRAIL-mediated activation-induced cell death
Edith M. Janssen, Nathalie M. Droin, Edward E. Lemmens, Michael J. Pinkoski, Steven J. Bensinger, Benjamin D. Ehst, Thomas S. Griffith, Douglas R. Green and Stephen P. Schoenberger Nature434, 88–93
(03 March 2005); doi:10.1038/nature03337
| First Paragraph | Full Text (HTML / PDF) |
letters to nature Two pathways converge at CED-10 to mediate actin rearrangement and corpse removal in C. elegans
Jason M. Kinchen , Juan Cabello, Doris Klingele, Kelvin Wong, Richard Feichtinger, Heinke Schnabel, Ralf Schnabel and Michael O. Hengartner Nature434, 93–99
(03 March 2005); doi:10.1038/nature03263
| First Paragraph | Full Text (HTML / PDF) |
review article The role of BH3-only proteins in the immune system
Andreas Strasser Nature Reviews Immunology5, 189–200
(March 2005); doi:10.1038/nri1568
| Summary | Full Text (HTML / PDF) |
February
letters to nature DRP-1-mediated mitochondrial fragmentation during EGL-1-induced cell death in C. elegans
Ravi Jagasia , Phillip Grote, Benedikt Westermann and Barbara Conradt Nature433, 754–760
(17 February 2005); doi:10.1038/nature03316
| First Paragraph | Full Text (HTML / PDF) |
article The p53QS transactivation-deficient mutant shows stress-specific apoptotic activity and induces embryonic lethality
Thomas M Johnson, Ester M Hammond, Amato Giaccia and Laura D Attardi Nature Genetics37, 145–152
(February 2005); doi:10.1038/ng1498
| Abstract | Full Text (HTML/PDF) |
January
article Lethal anemia caused by interferon-β produced in mouse embryos carrying undigested DNA
Hideyuki Yoshida, Yasutaka Okabe, Kohki Kawane, Hidehiro Fukuyama and Shigekazu Nagata Nature Immunology6, 49–56
(January 2005); doi:10.1038/ni1146
| Abstract | Full Text (HTML/PDF) |
news and views B-cell lymphoma: suppressing a tumor suppressor
Alexander Dent Nature Medicine11, 22
(January 2005); doi:10.1038/nm0105-22
| Full Text (HTML/PDF) |
letter IAPs are functionally non-equivalent and regulate effector caspases through distinct mechanisms
Tencho Tenev, Anna Zachariou, Rebecca Wilson, Mark Ditzel and Pascal Meier Nature Cell Biology7, 70–77
(January 2005); doi:10.1038/ncb1204
| First Paragraph | Full Text (HTML/PDF) |
letter Inhibitors of histone deacetylases induce tumor-selective apoptosis through activation of the death receptor pathway
Alessandra Insinga, Silvia Monestiroli, Simona Ronzoni, Vania Gelmetti, Francesco Marchesi, Andrea Viale, Lucia Altucci, Clara Nervi, Saverio Minucci and Pier Giuseppe Pelicci Nature Medicine11, 71–76
(January 2005); doi:10.1038/nm1160
| First Paragraph | Full Text (HTML/PDF) |
letter Tumor-selective action of HDAC inhibitors involves TRAIL induction in acute myeloid leukemia cells
Angela Nebbioso, Nicole Clarke, Emilie Voltz, Emmanuelle Germain, Concetta Ambrosino, Paola Bontempo, Rosana Alvarez, Ettore M Schiavone, Felicetto Ferrara, Francesco Bresciani, Alessandro Weisz, Angel R de Lera, Hinrich Gronemeyer and Lucia Altucci Nature Medicine11, 77–84
(January 2005); doi:10.1038/nm1161
| First Paragraph | Full Text (HTML/PDF) |
news and views Autoimmunity and apoptosis: refusing to go quietly
Donna L Bratton and Peter M Henson Nature Medicine11, 26–27
(January 2005); doi:10.1038/nm0105-26
| Full Text (HTML/PDF) |
article Signaling by the kinase MINK is essential in the negative selection of autoreactive thymocytes
Nami McCarty, Silke Paust, Koichi Ikizawa, Ippeita Dan, Xiaoyan Li and Harvey Cantor Nature Immunology6, 65–72
(January 2005); doi:10.1038/ni1145
| Abstract | Full Text (HTML/PDF) |
news and views Signaling negative selection: is MINK the missing link?
Ed Palmer Nature Immunology6, 9–10
(January 2005); doi:10.1038/ni0105-9
| Full Text (HTML/PDF) |
