Research library: Cancer
2003: December | November
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December
news and views
Push me, pull you
Charlotte Schubert
Nature Medicine 9, 1466
(December 2003); doi:10.1038/nm1203-1466
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review article
Applying the principles of stem-cell biology to cancer
Ricardo Pardal, Michael F. Clarke and Sean J. Morrison
Nature Reviews Cancer 3, 895–902
(December 2003); doi:10.1038/nrc1232
| Abstract | Full Text (HTML / PDF) |
review article
Intravital imaging of cell movement in tumours
John Condeelis and Jeffrey E. Segall
Nature Reviews Cancer 3, 921–930
(December 2003); doi:10.1038/nrc1231
| Abstract | Full Text (HTML / PDF) |
perspectives
Comparative biology of mouse versus human cells: modelling human cancer in mice
Annapoorni Rangarajan and Robert A. Weinberg
Nature Reviews Cancer 3, 952–959
(December 2003); doi:10.1038/nrc1235
| Abstract | Full Text (HTML / PDF) |
review article
Met, metastasis, motility and more
Carmen Birchmeier , Walter Birchmeier , Ermanno Gherardi and George F. Vande Woude
Nature Reviews Molecular Cell Biology 4, 915–925
(December 2003); doi:10.1038/nrm1261
| Abstract | Full Text (HTML / PDF) |
article
Mast cell-derived tumor necrosis factor induces hypertrophy of draining lymph nodes during infection
James B McLachlan, Justin P Hart, Salvatore V Pizzo, Christopher P Shelburne, Herman F Staats, Michael D Gunn and Soman N Abraham
Nature Immunology 4, 1199–1205
(December 2003); doi:10.1038/ni1005
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news and views
Mast cells to the defense
Stephen J Galli and Susumu Nakae
Nature Immunology 4, 1160–1162
(December 2003); doi:10.1038/ni1203-1160
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review article
Hedgehog signalling in cancer formation and maintenance
Marina Pasca di Magliano and Matthias Hebrok
Nature Reviews Cancer 3, 903–911
(December 2003); doi:10.1038/nrc1229
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review article
The 14-3-3 cancer connection
Heiko Hermeking
Nature Reviews Cancer 3, 931–943
(December 2003); doi:10.1038/nrc1230
| Abstract | Full Text (HTML / PDF) |
news and views
Medicine: Taking apart a cancer protein
Pier Paolo Scaglioni and Pier Paolo Pandolfi
Nature 426, 512–513
(04 December 2003); doi:10.1038/426512a
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review article
Cancer pharmacogenetics: polymorphisms, pathways and beyond
Cornelia M. Ulrich, Kim Robien and Howard L. McLeod
Nature Reviews Cancer 3, 912–920
(December 2003); doi:10.1038/nrc1233
| Abstract | Full Text (HTML / PDF) |
perspectives
Opinion: Searching for the elusive targets of farnesyltransferase inhibitors
Saïd M. Sebti and Channing J. Der
Nature Reviews Cancer 3, 945–951
(December 2003); doi:10.1038/nrc1234
| Abstract | Full Text (HTML / PDF) |
November
article
Ex vivo identification, isolation and analysis of tumor-cytolytic T cells
Valerie Rubio, Tor B Stuge, Naileshni Singh, Michael R Betts, Jeffrey S Weber, Mario Roederer and Peter P Lee
Nature Medicine 9, 1377–1382
(November 2003); doi:10.1038/nm942
| Abstract | Full Text (HTML/PDF) |
letter
PML-RARA-targeted DNA vaccine induces protective immunity in a mouse model of leukemia
Rose Ann Padua, Jerome Larghero, Marie Robin, Carol le Pogam, Marie-Helene Schlageter, Sacha Muszlak, Jan Fric, Robert West, Philippe Rousselot, Thi Hai Phan, Liesbeth Mudde, Helene Teisserenc, Antoine F Carpentier, Scott Kogan, Laurent Degos, Marika Pla, J Michael Bishop, Freda Stevenson, Dominique Charron and Christine Chomienne
Nature Medicine 9, 1413–1417
(November 2003); doi:10.1038/nm949
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news and views
Cancer vaccine targets leukemia
John Donnelly
Nature Medicine 9, 1354–1356
(November 2003); doi:10.1038/nm1103-1354
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review article
AP-1: a double-edged sword in tumorigenesis
Robert Eferl and Erwin F. Wagner
Nature Reviews Cancer 3, 859–868
(November 2003); doi:10.1038/nrc1209
| Abstract | Full Text (HTML / PDF) |
review article
Aromatase inhibitors for breast cancer: lessons from the laboratory
Stephen R.D. Johnston and Mitch Dowsett
Nature Reviews Cancer 3, 821–831
(November 2003); doi:10.1038/nrc1211
| Abstract | Full Text (HTML / PDF) |
review article
Cytostatic and apoptotic actions of TGF-β in homeostasis and cancer
Peter M. Siegel and Joan Massagué
Nature Reviews Cancer 3, 807–820
(November 2003); doi:10.1038/nrc1208
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article
Tat-binding protein-1, a component of the 26S proteasome, contributes to the E3 ubiquitin ligase function of the von Hippel-Lindau protein
Paul G Corn, E Robert McDonald III, James G Herman and Wafik S El-Deiry
Nature Genetics 35, 229–237
(November 2003); doi:10.1038/ng1254
| Abstract | Full Text (HTML/PDF) |
letter
Loss of collagenase-2 confers increased skin tumor susceptibility to male mice
Milagros Balbín, Antonio Fueyo, Angus M Tester, Alberto M Pendás, Ana S Pitiot, Aurora Astudillo, Christopher M Overall, Steven D Shapiro and Carlos López-Otín
Nature Genetics 35, 252–257
(November 2003); doi:10.1038/ng1249
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perspectives
Opinion: Merlin and ERM proteins: unappreciated roles in cancer development?
Andrea I. McClatchey
Nature Reviews Cancer 3, 877–883
(November 2003); doi:10.1038/nrc1213
| Abstract | Full Text (HTML / PDF) |
October
review article
Cannabinoids: potential anticancer agents
Manuel Guzmán
Nature Reviews Cancer 3, 745–755
(October 2003); doi:10.1038/nrc1188
| Abstract | Full Text (HTML / PDF) |
review article
Cancer chemoprevention with dietary phytochemicals
Young-Joon Surh
Nature Reviews Cancer 3, 768–780
(October 2003); doi:10.1038/nrc1189
| Abstract | Full Text (HTML / PDF) |
perspectives
Innovation: New tools for functional mammalian cancer genetics
Thijn R. Brummelkamp and René Bernards
Nature Reviews Cancer 3, 781–789
(October 2003); doi:10.1038/nrc1191
| Abstract | Full Text (HTML / PDF) |
perspectives
Opinion: Proteomic analysis of cancer-cell mitochondria
Mukesh Verma, Jacob Kagan, David Sidransky and Sudhir Srivastava
Nature Reviews Cancer 3, 789–795
(October 2003); doi:10.1038/nrc1192
| Abstract | Full Text (HTML / PDF) |
letter
A novel ubiquitin ligase is deficient in Fanconi anemia
Amom Ruhikanta Meetei, Johan P de Winter, Annette L Medhurst, Michael Wallisch, Quinten Waisfisz, Henri J van de Vrugt, Anneke B Oostra, Zhijiang Yan, Chen Ling, Colin E Bishop, Maureen E Hoatlin, Hans Joenje and Weidong Wang
Nature Genetics 35, 165–170
(October 2003); doi:10.1038/ng1241
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news and views
FANCL, as in ligase
Markus Grompe
Nature Genetics 35, 113–114
(October 2003); doi:10.1038/ng1003-113
| Full Text (HTML/PDF) |
letters to nature
Widespread requirement for Hedgehog ligand stimulation in growth of digestive tract tumours
David M. Berman , Sunil S. Karhadkar , Anirban Maitra, Rocio Montes de Oca, Meg R. Gerstenblith, Kimberly Briggs, Antony R. Parker, Yutaka Shimada, James R. Eshleman, D. Neil Watkins and Philip A. Beachy
Nature 425, 846–851
(23 October 2003); doi:10.1038/nature01972
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letters to nature
Hedgehog is an early and late mediator of pancreatic cancer tumorigenesis
Sarah P. Thayer, Marina Pasca di Magliano, Patrick W. Heiser, Corinne M. Nielsen, Drucilla J. Roberts, Gregory Y. Lauwers, Yan Ping Qi, Stephan Gysin, Carlos Fernández-del Castillo, Vijay Yajnik, Bozena Antoniu, Martin McMahon, Andrew L. Warshaw and Matthias Hebrok
Nature 425, 851–856
(23 October 2003); doi:10.1038/nature02009
| First Paragraph | Full Text (HTML / PDF) |
news and views
Cancer: A twist in a hedgehog's tale
Matthew P. Scott
Nature 425, 780–782
(23 October 2003); doi:10.1038/425780a
| Full Text (HTML / PDF) |
brief communication
Genetic deficiency in Pparg does not alter development of experimental prostate cancer
Enrique Saez, Peter Olson and Ronald M Evans
Nature Medicine 9, 1265–1266
(October 2003); doi:10.1038/nm928
| First Paragraph | Full Text (HTML/PDF) |
review article
The role of Notch in tumorigenesis: oncogene or tumour suppressor?
Freddy Radtke and Kenneth Raj
Nature Reviews Cancer 3, 756–767
(October 2003); doi:10.1038/nrc1186
| Summary | Full Text (HTML / PDF) |
review article
Mechanisms of sarcoma development
Lee J. Helman and Paul Meltzer
Nature Reviews Cancer 3, 685–694
(September 2003); doi:10.1038/nrc1168
| Abstract | Full Text (HTML / PDF) |
review article
From developmental disorder to heritable cancer: it's all in the BMP/TGF-β family
Kristin A. Waite and Charis Eng
Nature Reviews Genetics 4, 763–773
(October 2003); doi:10.1038/nrg1178
| Abstract | Full Text (HTML / PDF) |
review article
Targeting HIF-1 for cancer therapy
Gregg L. Semenza
Nature Reviews Cancer 3, 721–732
(October 2003); doi:10.1038/nrc1187
| Abstract | Full Text (HTML / PDF) |
letters to nature
Jelly belly protein activates the receptor tyrosine kinase Alk to specify visceral muscle pioneers
Hsiu-Hsiang Lee, Audra Norris, Joseph B. Weiss and Manfred Frasch
Nature 425, 507–512
(02 October 2003); doi:10.1038/nature01916
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letters to nature
Jeb signals through the Alk receptor tyrosine kinase to drive visceral muscle fusion
Camilla Englund, Christina E. Lorén, Caroline Grabbe, Gaurav K. Varshney, Fabienne Deleuil, Bengt Hallberg and Ruth H. Palmer
Nature 425, 512–516
(02 October 2003); doi:10.1038/nature01950
| First Paragraph | Full Text (HTML / PDF) |
news and views
Developmental biology: Partners united
Matthew Freeman
Nature 425, 468–469
(02 October 2003); doi:10.1038/425468a
| Full Text (HTML / PDF) |
news and views
Cell biology: The hippo hypothesis
Michael E. Rothenberg and Yuh-Nung Jan
Nature 425, 469–470
(02 October 2003); doi:10.1038/425469a
| Full Text (HTML / PDF) |
brief communication
Pharmacologic inactivation of kinase suppressor of ras-1 abrogates Ras-mediated pancreatic cancer
H. Rosie Xing, Carlos Cordon-Cardo, Xinzhu Deng, William Tong, Luis Campodonico, Zvi Fuks and Richard Kolesnick
Nature Medicine 9, 1267–1268
(October 2003); doi:10.1038/nm927
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September
letters to nature
A high-affinity conformation of Hsp90 confers tumour selectivity on Hsp90 inhibitors
Adeela Kamal, Lia Thao, John Sensintaffar, Lin Zhang, Marcus F. Boehm, Lawrence C. Fritz and Francis J. Burrows
Nature 425, 407–410
(25 September 2003); doi:10.1038/nature01913
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news and views
Cancer: The rules of attraction
Len Neckers and Yong-Sok Lee
Nature 425, 357–359
(25 September 2003); doi:10.1038/425357a
| Full Text (HTML / PDF) |
article
Interaction between leukemic-cell VLA-4 and stromal fibronectin is a decisive factor for minimal residual disease of acute myelogenous leukemia
Takuya Matsunaga, Naofumi Takemoto, Tsutomu Sato, Rishu Takimoto, Ikuta Tanaka, Akihito Fujimi, Takehide Akiyama, Hiroyuki Kuroda, Yutaka Kawano, Masayoshi Kobune, Junji Kato, Yasuo Hirayama, Sumio Sakamaki, Kyuhei Kohda, Kensuke Miyake and Yoshiro Niitsu
Nature Medicine 9, 1158–1165
(September 2003); doi:10.1038/nm909
| Abstract | Full Text (HTML/PDF) |
letters to nature
Chemokine receptor CXCR4 downregulated by von Hippel-Lindau tumour suppressor pVHL
Peter Staller, Jitka Sulitkova, Joanna Lisztwan, Holger Moch, Edward J. Oakeley and Wilhelm Krek
Nature 425, 307–311
(18 September 2003); doi:10.1038/nature01874
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news and views
Cancer: Cues for migration
René Bernards
Nature 425, 247–248
(18 September 2003); doi:10.1038/425247a
| Full Text (HTML / PDF) |
letter
Sphingosylphosphorylcholine regulates keratin network architecture and visco-elastic properties of human cancer cells
Michael Beil, Alexandre Micoulet, Götz von Wichert, Stephan Paschke, Paul Walther, M. Bishr Omary, Paul P. Van Veldhoven, Ulrike Gern, Elke Wolff-Hieber, Juliane Eggermann, Johannes Waltenberger, Guido Adler, Joachim Spatz and Thomas Seufferlein
Nature Cell Biology 5, 803–811
(September 2003); doi:10.1038/ncb1037
| First Paragraph | Full Text (HTML/PDF) |
review article
Mechanisms of sarcoma development
Lee J. Helman and Paul Meltzer
Nature Reviews Cancer 3, 685–694
(September 2003); doi:10.1038/nrc1168
| Abstract | Full Text (HTML / PDF) |
review article
Cancer susceptibility in the mouse: genetics, biology and implications for human cancer
Peter Demant
Nature Reviews Genetics 4, 721–734
(September 2003); doi:10.1038/nrg1157
| Abstract | Full Text (HTML / PDF) |
news and views
Cardiovascular biology: Signalling silenced
Edward M. Conway and Peter Carmeliet
Nature 425, 139–141
(11 September 2003); doi:10.1038/425139a
| Full Text (HTML / PDF) |
news and views
Boosting p53 with interferon and viruses
Jan Vilcek
Nature Immunology 4, 825–826
(September 2003); doi:10.1038/ni0903-825
| Full Text (HTML/PDF) |
review article
The role of FLT3 in haematopoietic malignancies
Derek L. Stirewalt and Jerald P. Radich
Nature Reviews Cancer 3, 650–665
(September 2003); doi:10.1038/nrc1169
| Abstract | Full Text (HTML / PDF) |
August
review article
Control of gut differentiation and intestinal-type gastric carcinogenesis
Yasuhito Yuasa
Nature Reviews Cancer 3, 592–600
(August 2003); doi:10.1038/nrc1141
| Abstract | Full Text (HTML / PDF) |
review article
Chemoprevention of colon cancer by calcium, vitamin D and folate: molecular mechanisms
Sergio A. Lamprecht and Martin Lipkin
Nature Reviews Cancer 3, 601–614
(August 2003); doi:10.1038/nrc1144
| Abstract | Full Text (HTML / PDF) |
Scientific Report
RAL GTPases are linchpin modulators of human tumour-cell proliferation and survival
Yuchen Chien & Michael A. White
EMBO reports 4, 800–806
(August 2003); doi:10.1038/sj.embor.embor899
| Full Text (HTML/PDF) |
news and views
Cell biology: Tumour jailbreak
Kenneth M. Yamada
Nature 424, 889–890
(21 August 2003); doi:10.1038/424889a
| Full Text (HTML / PDF) |
perspectives
Diverse cellular and molecular mechanisms contribute to epithelial plasticity and metastasis
Stefan Grünert, Martin Jechlinger and Hartmut Beug
Nature Reviews Molecular Cell Biology 4, 657–665
(August 2003); doi:10.1038/nrm1175
| Abstract | Full Text (HTML / PDF) |
review article
Caveolae: mining little caves for new cancer targets
Lucy A. Carver and Jan E. Schnitzer
Nature Reviews Cancer 3, 571–581
(August 2003); doi:10.1038/nrc1146
| Abstract | Full Text (HTML / PDF) |
letters to nature
CYLD is a deubiquitinating enzyme that negatively regulates NF-κB activation by TNFR family members
Eirini Trompouki, Eudoxia Hatzivassiliou, Theodore Tsichritzis, Hannah Farmer, Alan Ashworth and George Mosialos
Nature 424, 793–796
(14 August 2003); doi:10.1038/nature01803
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letters to nature
Loss of the cylindromatosis tumour suppressor inhibits apoptosis by activating NF-κB
Thijn R. Brummelkamp, Sebastian M. B. Nijman, Annette M. G. Dirac and René Bernards
Nature 424, 797–801
(14 August 2003); doi:10.1038/nature01811
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letters to nature
The tumour suppressor CYLD negatively regulates NF-κB signalling by deubiquitination
Andrew Kovalenko Christine Chable-Bessia, Giuseppina Cantarella, Alain Israël, David Wallach & Gilles Courtois
Nature 424, 801–805
(14 August 2003); doi:10.1038/nature01802
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news and views
Signal transduction: Aspirin, ubiquitin and cancer
Keith D. Wilkinson
Nature 424, 738–739
(14 August 2003); doi:10.1038/424738a
| Full Text (HTML / PDF) |
review article
The emerging role of lysophosphatidic acid in cancer
Gordon B. Mills and Wouter H. Moolenaar
Nature Reviews Cancer 3, 582–591
(August 2003); doi:10.1038/nrc1143
| Abstract | Full Text (HTML / PDF) |
news and views
Aurora and the hunt for cancer-modifying genes
William Dove
Nature Genetics 34, 353–354
(August 2003); doi:10.1038/ng0803-353
| Full Text (HTML/PDF) |
article
Integration of interferon-α/β signalling to p53 responses in tumour suppression and antiviral defence
Akinori Takaoka, Sumio Hayakawa, Hideyuki Yanai, Dagmar Stoiber, Hideo Negishi, Hideaki Kikuchi, Shigeru Sasaki, Kohzoh Imai, Tsukasa Shibue, Kenya Honda and Tadatsugu Taniguchi
Nature 424, 516–523
(31 July 2003); doi:10.1038/nature01850
| Abstract | Full Text (HTML / PDF) |
letters to nature
Essential role for the peroxiredoxin Prdx1 in erythrocyte antioxidant defence and tumour suppression
Carola A. Neumann, Daniela S. Krause, Christopher V. Carman, Shampa Das, Devendra P. Dubey, Jennifer L. Abraham, Roderick T. Bronson, Yuko Fujiwara, Stuart H. Orkin and Richard A. Van Etten
Nature 424, 561–565
(31 July 2003); doi:10.1038/nature01819
| First Paragraph | Full Text (HTML / PDF) |
article
Differing modes of tumour cell invasion have distinct requirements for Rho/ROCK signalling and extracellular proteolysis
Erik Sahai and Christopher J. Marshall
Nature Cell Biology 5, 711–719
(August 2003); doi:10.1038/ncb1019
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news and views
New dimensions in cell migration
Donna J. Webb and Alan F. Horwitz
Nature Cell Biology 5, 690–692
(August 2003); doi:10.1038/ncb0803-690
| Full Text (HTML/PDF) |
article
Transcription factor Egr-1 supports FGF-dependent angiogenesis during neovascularization and tumor growth
Roger G. Fahmy, Crispin R. Dass, Lun-Quan Sun, Colin N. Chesterman and Levon M. Khachigian
Nature Medicine 9, 1026–1032
(August 2003); doi:10.1038/nm905
| Abstract | Full Text (HTML/PDF) |
news and views
Road map to metastasis
Laura J. Van't Veer and Britta Weigelt
Nature Medicine 9, 999–1000
(August 2003); doi:10.1038/nm0803-999b
| Full Text (HTML/PDF) |
review article
The genetics of malignant melanoma: lessons from mouse and man
Lynda Chin
Nature Reviews Cancer 3, 559–570
(August 2003); doi:10.1038/nrc1145
| Abstract | Full Text (HTML / PDF) |
article
Identification of Stk6/STK15 as a candidate low-penetrance tumor-susceptibility gene in mouse and human
Amanda Ewart-Toland, Paraskevi Briassouli, John P. de Koning, Jian-Hua Mao, Jinwei Yuan, Florence Chan, Lucy MacCarthy-Morrogh, Bruce A. J. Ponder, Hiroki Nagase, John Burn, Sarah Ball, Maria Almeida, Spiros Linardopoulos and Allan Balmain
Nature Genetics 34, 403–412
(August 2003); doi:10.1038/ng1220
| Abstract | Full Text (HTML/PDF) |
July
letter
Inactivating E2f1 reverts apoptosis resistance and cancer sensitivity in Trp53-deficient mice
Norbert M. Wikonkal, Eva Remenyik, Dejan Knezevic, Wengeng Zhang, Ming Liu, Hongyu Zhao, T. R. Berton, David G. Johnson and Douglas E. Brash
Nature Cell Biology 5, 655–660
(July 2003); doi:10.1038/ncb1001
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news and views
The yin and yang of E2F-1: balancing life and death
Nicholas B. La Thangue
Nature Cell Biology 5, 587–589
(July 2003); doi:10.1038/ncb0703-587
| Full Text (HTML/PDF) |
news and views
Angiogenesis inhibitors: motivators of metastasis?
Patricia S Steeg
Nature Medicine 9, 822–823
(July 2003); doi:10.1038/nm0703-822
| Full Text (HTML/PDF) |
letters to nature
Acute mutation of retinoblastoma gene function is sufficient for cell cycle re-entry
Julien Sage, Abigail L. Miller, Pedro A. Pérez-Mancera, Julianne M. Wysocki and Tyler Jacks
Nature 424, 223–228
(10 July 2003); doi:10.1038/nature01764
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news and views
Tumour suppressors: Timing will tell
Anton Berns
Nature 424, 140–141
(10 July 2003); doi:10.1038/424140a
| Full Text (HTML / PDF) |
review article
Molecular mechanisms of glioma invasiveness: the role of proteases
Jasti S. Rao
Nature Reviews Cancer 3, 489–501
(July 2003); doi:10.1038/nrc1121
| Summary | Full Text (HTML / PDF) |
review article
Ovarian cancer: strategies for overcoming resistance to chemotherapy
Roshan Agarwal and Stan B. Kaye
Nature Reviews Cancer 3, 502–516
(July 2003); doi:10.1038/nrc1123
| Summary | Full Text (HTML / PDF) |
research article
A conditionally replicating adenovirus targeted to tumor cells through activated RAS/P-MAPK-selective mRNA stabilization
Atique Ahmed, Jill Thompson, Lisa Emiliusen, Stephen Murphy, R Daniel Beauchamp, Kaori Suzuki, Ramon Alemany, Kevin Harrington and Richard G Vile
Nature Biotechnology 21, 771–777
(July 2003); doi:10.1038/nbt835
| Abstract | Full Text (HTML/PDF) |
news and views
Vectorology recapitulates virology—will it capitulate oncology?
Estaurdo Aguilar-Cordova
Nature Biotechnology 21, 756–757
(July 2003); doi:10.1038/nbt0703-756
| Full Text (HTML/PDF) |
June
letters to nature
Enhanced gravi- and phototropism in plant mdr mutants mislocalizing the auxin efflux protein PIN1
Bosl Noh, Anindita Bandyopadhyay, Wendy Ann Peer, Edgar P. Spalding and Angus S. Murphy
Nature 423, 999–1002
(26 June 2003); doi:10.1038/nature01716
| First Paragraph | Full Text (HTML / PDF) |
article
Bcl11a is essential for normal lymphoid development
Pentao Liu, Jonathan R Keller, Mariaestela Ortiz, Lino Tessarollo, Rivka A Rachel, Takuro Nakamura, Nancy A Jenkins and Neal G Copeland
Nature Immunology 4, 525–532
(June 2003); doi:10.1038/ni925
| Abstract | Full Text (HTML/PDF) |
article
Bcl11b is required for differentiation and survival of αβ T lymphocytes
Yuichi Wakabayashi, Hisami Watanabe, Jun Inoue, Naoki Takeda, Jun Sakata, Yukio Mishima, Jiro Hitomi, Takashi Yamamoto, Masanori Utsuyama, Ohtsura Niwa, Shinichi Aizawa and Ryo Kominami
Nature Immunology 4, 533–539
(June 2003); doi:10.1038/ni927
| Abstract | Full Text (HTML/PDF) |
news and views
Bcl11: sibling rivalry in lymphoid development
Scott K Durum
Nature Immunology 4, 512–514
(June 2003); doi:10.1038/ni0603-512
| Full Text (HTML/PDF) |
review article
Vasculogenic mimicry and tumour-cell plasticity: lessons from melanoma
Mary J. C. Hendrix, Elisabeth A. Seftor, Angela R. Hess and Richard E. B. Seftor
Nature Reviews Cancer 3, 411–421
(June 2003); doi:10.1038/nrc1092
| Summary | Full Text (HTML / PDF) |
perspectives
RAS oncogenes: the first 30 years
Marcos Malumbres and Mariano Barbacid
Nature Reviews Cancer 3, 459–465
(June 2003); doi:10.1038/nrc1097
| Summary | Full Text (HTML / PDF) |
news and views
Meddling with methylation
Chih-Lin Hsieh and Peter A. Jones
Nature Cell Biology 5, 502–504
(June 2003); doi:10.1038/ncb0603-502
| Full Text (HTML/PDF) |
review article
Molecular views of recombination proteins and their control
Stephen C. West
Nature Reviews Molecular Cell Biology 4, 435–445
(June 2003); doi:10.1038/nrm1127
| Summary | Full Text (HTML / PDF) |
letter
Targeting exogenous genes to tumor angiogenesis by transplantation of genetically modified hematopoietic stem cells
Michele De Palma, Mary Anna Venneri, Cristina Roca and Luigi Naldini
Nature Medicine 9, 789–795
(June 2003); doi:10.1038/nm871
| First Paragraph | Full Text (HTML/PDF) |
review article
Regulation of angiogenesis by hypoxia: role of the HIF system
Christopher W Pugh and Peter J Ratcliffe
Nature Medicine 9, 677–684
(June 2003); doi:10.1038/nm0603-677
| Abstract | Full Text (HTML/PDF) |
review article
Angiogenesis: Tumorigenesis and the angiogenic switch
Gabriele Bergers and Laura E. Benjamin
Nature Reviews Cancer 3, 401–410
(June 2003); doi:10.1038/nrc1093
| Summary | Full Text (HTML / PDF) |
review article
Stem-cell hierarchy in skin cancer
Jesus Perez-Losada and Allan Balmain
Nature Reviews Cancer 3, 434–443
(June 2003); doi:10.1038/nrc1095
| Summary | Full Text (HTML / PDF) |
news and views
Manipulating hematopoietic stem cell amplification with Wnt
Connie J Eaves PhD
Nature Immunology 4, 511–512
(June 2003); doi:10.1038/ni0603-511
| Full Text (HTML/PDF) |
article
A nonpeptidyl mimic of superoxide dismutase, M40403, inhibits dose-limiting hypotension associated with interleukin-2 and increases its antitumor effects
Wolfram E Samlowski, Ryan Petersen, Salvatore Cuzzocrea, Heather Macarthur, Damali Burton, John R McGregor and Daniela Salvemini
Nature Medicine 9, 750–755
(June 2003); doi:10.1038/nm874
| Abstract | Full Text (HTML/PDF) |
news and views
Biological drug duo delivers one-two tumor punch
Jeffrey A Sosman and James W Mier
Nature Medicine 9, 649–650
(June 2003); doi:10.1038/nm0603-649
| Full Text (HTML/PDF) |
review article
Contribution of stem cells and differentiated cells to epidermal tumours
David M. Owens and Fiona M. Watt
Nature Reviews Cancer 3, 444–451
(June 2003); doi:10.1038/nrc1096
| Summary | Full Text (HTML / PDF) |
letter
Gene expression phenotypic models that predict the activity of oncogenic pathways
Erich Huang, Seiichi Ishida, Jennifer Pittman, Holly Dressman, Andrea Bild, Mark Kloos, Mark D'Amico, Richard G Pestell, Mike West and Joseph R Nevins
Nature Genetics 34, 226–230
(June 2003); doi:10.1038/ng1167
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news and views
Cancer: Out of air is not out of action
Donald P. Bottaro and Lance A. Liotta
Nature 423, 593–595
(05 June 2003); doi:10.1038/423593a
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article
Pigment epithelium-derived factor regulates the vasculature and mass of the prostate and pancreas
Jennifer A Doll, Veronica M Stellmach, Noël P Bouck, Anders RJ Bergh, Chung Lee, Lisa P Abramson, Mona L Cornwell, Michael R Pins, Jayme Borensztajn and Susan E Crawford
Nature Medicine 9, 774–780
(June 2003); doi:10.1038/nm870
| Abstract | Full Text (HTML/PDF) |
review article
Basement membranes: structure, assembly and role in tumour angiogenesis
Raghu Kalluri
Nature Reviews Cancer 3, 422–433
(June 2003); doi:10.1038/nrc1094
| Summary | Full Text (HTML / PDF) |
May
article
Structure of the replicative helicase of the oncoprotein SV40 large tumour antigen
Dawei Li, Rui Zhao, Wayne Lilyestrom, Dahai Gai, Rongguang Zhang, James A. DeCaprio, Ellen Fanning, Andrzej Jochimiak, Gerda Szakonyi and Xiaojiang S. Chen
Nature 423, 512–518
(29 May 2003); doi:10.1038/nature01691
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letters to nature
Role of ERas in promoting tumour-like properties in mouse embryonic stem cells
Kazutoshi Takahashi, Kaoru Mitsui and Shinya Yamanaka
Nature 423, 541–545
(29 May 2003); doi:10.1038/nature01646
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article
A role for Wnt signalling in self-renewal of haematopoietic stem cells
Tannishtha Reya, Andrew W. Duncan, Laurie Ailles, Jos Domen, David C. Scherer, Karl Willert, Lindsay Hintz, Roel Nusse and Irving L. Weissman
Nature 423, 409–414
(22 May 2003); doi:10.1038/nature01593
| Abstract | Full Text (HTML / PDF) |
letters to nature
Wnt proteins are lipid-modified and can act as stem cell growth factors
Karl Willert, Jeffrey D. Brown, Esther Danenberg, Andrew W. Duncan, Irving L. Weissman, Tannishtha Reya, John R. Yates III and Roel Nusse
Nature 423, 448–452
(22 May 2003); doi:10.1038/nature01611
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letters to nature
Deficiency of the adaptor SLP-65 in pre-B-cell acute lymphoblastic leukaemia
Hassan Jumaa, Lukas Bossaller, Karina Portugal, Bettina Storch, Michael Lotz, Alexandra Flemming, Martin Schrappe, Ville Postila, Pekka Riikonen, Jukka Pelkonen, Charlotte M. Niemeyer and Michael Reth
Nature 423, 452–456
(22 May 2003); doi:10.1038/nature01608
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article
Disruption of the Fanconi anemia-BRCA pathway in cisplatin-sensitive ovarian tumors
Toshiyasu Taniguchi, Marc Tischkowitz, Najim Ameziane, Shirley V. Hodgson, Christopher G. Mathew, Hans Joenje, Samuel C. Mok and Alan D. D'Andrea
Nature Medicine 9, 568–574
(May 2003); doi:10.1038/nm852
| Abstract | Full Text (HTML/PDF) |
news and views
Cisplatin and the sensitive cell
Grover C. Bagby and Susan B. Olson
Nature Medicine 9, 513–514
(May 2003); doi:10.1038/nm0503-513
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review article
Tumour-cell invasion and migration: diversity and escape mechanisms
Peter Friedl and Katarina Wolf
Nature Reviews Cancer 3, 362–374
(May 2003); doi:10.1038/nrc1075
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article
Bmi-1 determines the proliferative capacity of normal and leukaemic stem cells
Julie Lessard and Guy Sauvageau
Nature 423, 255–260
(15 May 2003); doi:10.1038/nature01572
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letters to nature
Bmi-1 is required for maintenance of adult self-renewing haematopoietic stem cells
In-kyung Park, Dalong Qian, Mark Kiel, Michael W. Becker, Michael Pihalja, Irving L. Weissman, Sean J. Morrison and Michael F. Clarke
Nature 423, 302–305
(15 May 2003); doi:10.1038/nature01587
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news and views
Stem cells: Self-renewal writ in blood
John E. Dick
Nature 423, 231–233
(15 May 2003); doi:10.1038/423231a
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perspectives
Cancer revoked: oncogenes as therapeutic targets
Dean W. Felsher
Nature Reviews Cancer 3, 375–379
(May 2003); doi:10.1038/nrc1070
| Summary | Full Text (HTML / PDF) |
perspectives
Re-evaluating the role of heat-shock protein-peptide interactions in tumour immunity
Christopher V. Nicchitta
Nature Reviews Immunology 3, 427–432
(May 2003); doi:10.1038/nri1089
| Summary | Full Text (HTML / PDF) |
review article
The circadian clock: pacemaker and tumour suppressor
Loning Fu and Cheng Chi Lee
Nature Reviews Cancer 3, 350–361
(May 2003); doi:10.1038/nrc1072
| Summary | Full Text (HTML / PDF) |
news and views
Small changes in Wnt signalling
Sarah Greaves
Nature Cell Biology 5, 387
(May 2003); doi:10.1038/ncb0503-387
| Full Text (HTML/PDF) |
review article
Cancer and ageing: rival demons?
Judith Campisi
Nature Reviews Cancer 3, 339–349
(May 2003); doi:10.1038/nrc1073
| Summary | Full Text (HTML / PDF) |
letter
Melanoma mouse model implicates metabotropic glutamate signaling in melanocytic neoplasia
Pamela M. Pollock, Karine Cohen-Solal, Raman Sood, Jin Namkoong, Jeffrey J. Martino, Aruna Koganti, Hua Zhu, Christiane Robbins, Izabela Makalowska, Seung-Shick Shin, Yari Marin, Kathleen G. Roberts, Laura M. Yudt, Amy Chen, Jun Cheng, Arturo Incao, Heather W. Pinkett, Christopher L Graham, Karen Dunn, Steven M. Crespo-Carbone, Kerine R. Mackason, Kevin B. Ryan, Daniel Sinsimer, James Goydos, Kenneth R. Reuhl, Michael Eckhaus, Paul S. Meltzer, William J. Pavan, Jeffrey M. Trent and Suzie Chen
Nature Genetics 34, 108–112
(May 2003); doi:10.1038/ng1148
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April
letters to nature
Chibby, a nuclear β-catenin-associated antagonist of the Wnt/Wingless pathway
Ken-Ichi Takemaru, Shinji Yamaguchi, Young Sik Lee, Yang Zhang, Richard W. Carthew and Randall T. Moon
Nature 422, 905–909
(24 April 2003); doi:10.1038/nature01570
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news and views
Cancer: Escape from inhibition
Sara A. Courtneidge
Nature 422, 827–828
(24 April 2003); doi:10.1038/422827a
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review article
Issues and progress with protein kinase inhibitors for cancer treatment
Janet Dancey and Edward A. Sausville
Nature Reviews Drug Discovery 2, 296–313
(April 2003); doi:10.1038/nrd1066
| Summary | Full Text (HTML / PDF) |
original paper
Regulation of hairy-cell survival through constitutive activation of mitogen-activated protein kinase pathways
Aura S. Kamiguti, Robert J. Harris, Joseph R. Slupsky, Peter K. Baker, John C. Cawley and Mirko Zuzel
Oncogene 22, 2272–2284
(17 April 2003); doi:10.1038/sj.onc.1206398
| Abstract | Full Text (HTML/PDF) |
letters to nature
Coordinated histone modifications mediated by a CtBP co-repressor complex
Yujiang Shi, Jun-ichi Sawada, Guangchao Sui, El Bachir Affar, Johnathan R. Whetstine, Fei Lan, Hidesato Ogawa, Margaret Po-Shan Luke, Yoshihiro Nakatani and Yang Shi
Nature 422, 735–738
(17 April 2003); doi:10.1038/nature01550
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review article
Radical causes of cancer
S. Perwez Hussain, Lorne J. Hofseth and Curtis C. Harris
Nature Reviews Cancer 3, 276–285
(April 2003); doi:10.1038/nrc1046
| Summary | Full Text (HTML / PDF) |
original paper
Heregulin-β1 regulates the estrogen receptor-α gene expression and activity via the ErbB2/PI 3-K/Akt pathway
Gerald E Stoica, Thomas F Franke, Anton Wellstein, Elisha Morgan, Frank Czubayko, Heinz-Joachim List, Ronald Reiter, Mary Beth Martin and Adriana Stoica
Oncogene 22, 2073–2087
(10 April 2003); doi:10.1038/sj.onc.1206311
| Abstract |
review article
Senescence, apoptosis and therapy — cutting the lifelines of cancer
Clemens A. Schmitt
Nature Reviews Cancer 3, 286–295
(April 2003); doi:10.1038/nrc1044
| Summary | Full Text (HTML / PDF) |
original paper
MAP kinase activation by interleukin-9 in lymphoid and mast cell lines
Jean-Baptiste Demoulin, Jamila Louahed, Laure Dumoutier, Monique Stevens and Jean-Christophe Renauld
Oncogene 22, 1763–1770
(27 March 2003); doi:10.1038/sj.onc.1206253
| Abstract |
review
Tumor necrosis factor signaling
H Wajant, K Pfizenmaier and P Scheurich
Cell Death and Differentiation 10, 45–65
(January 2003); doi:10.1038/sj.cdd.4401189
| Abstract |
review
Apo2L/TRAIL and its death and decoy receptors
H N LeBlanc and A Ashkenazi
Cell Death and Differentiation 10, 66–75
(January 2003); doi:10.1038/sj.cdd.4401187
| Abstract |
March
review article
Mannose 6-phosphate receptors: new twists in the tale
Pradipta Ghosh, Nancy M. Dahms and Stuart Kornfeld
Nature Reviews Molecular Cell Biology 4, 202–213
(March 2003); doi:10.1038/nrm1050
| Summary | Full Text (HTML / PDF) |
review article
Janus-like role of regulatory iNKT cells in autoimmune disease and tumour immunity
S. Brian Wilson and Terry L. Delovitch
Nature Reviews Immunology 3, 211–222
(March 2003); doi:10.1038/nri1028
| Summary | Full Text (HTML / PDF) |
article
A novel viral mechanism for dysregulation of β-catenin in Kaposi's sarcoma-associated herpesvirus latency
Masahiro Fujimuro, Frederick Y. Wu, Colette apRhys, Henry Kajumbula, David B. Young, Gary S. Hayward and S. Diane Hayward
Nature Medicine 9, 300–306
(March 2003); doi:10.1038/nm829
| Abstract | Full Text (HTML/PDF) |
news and views
Kaposi virus scores cancer coup
Chris Boshoff
Nature Medicine 9, 261–262
(March 2003); doi:10.1038/nm0303-261
| Full Text (HTML/PDF) |
review article
Does the ribosome translate cancer?
Davide Ruggero and Pier Paolo Pandolfi
Nature Reviews Cancer 3, 179–192
(March 2003); doi:10.1038/nrc1015
| Summary | Full Text (HTML / PDF) |
letter
Notch1 functions as a tumor suppressor in mouse skin
Michael Nicolas, Anita Wolfer, Kenneth Raj, J. Alain Kummer, Pleasantine Mill, Mascha van Noort, Chi-chung Hui, Hans Clevers, G. Paolo Dotto and Freddy Radtke
Nature Genetics 33, 416–421
(March 2003); doi:10.1038/ng1099
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letters to nature
Hedgehog signalling within airway epithelial progenitors and in small-cell lung cancer
D. Neil Watkins, David M. Berman, Scott G. Burkholder, Baolin Wang, Philip A. Beachy and Stephen B. Baylin
Nature 422, 313–317
(20 March 2003); doi:10.1038/nature01493
| First Paragraph | Full Text (HTML / PDF) |
perspectives
Natural versus adaptive regulatory T cells
Jeffrey A. Bluestone and Abul K. Abbas
Nature Reviews Immunology 3, 253–257
(March 2003); doi:10.1038/nri1032
| Summary | Full Text (HTML / PDF) |
review article
Neuroblastoma: biological insights into a clinical enigma
Garrett M. Brodeur
Nature Reviews Cancer 3, 203–216
(March 2003); doi:10.1038/nrc1014
| Summary | Full Text (HTML / PDF) |
letters to nature
Loss of integrin αvβ6-mediated TGF-β activation causes Mmp12-dependent emphysema
David G. Morris, Xiaozhu Huang, Naftali Kaminski, Yanli Wang, Steven D. Shapiro, Gregory Dolganov, Adam Glick and Dean Sheppard
Nature 422, 169–173
(13 March 2003); doi:10.1038/nature01413
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news and views
Medicine: Smoke signals for lung disease
Anita B. Roberts
Nature 422, 130–131
(13 March 2003); doi:10.1038/422130a
| Full Text (HTML / PDF) |
letter
p53RDL1 regulates p53-dependent apoptosis
Chizu Tanikawa, Koichi Matsuda, Seisuke Fukuda, Yusuke Nakamura and Hirofumi Arakawa
Nature Cell Biology 5, 216–223
(March 2003); doi:10.1038/ncb943
| First Paragraph | Full Text (HTML/PDF) |
letter
Mutated APC and Asef are involved in the migration of colorectal tumour cells
Yoshihiro Kawasaki, Rina Sato and Tetsu Akiyama
Nature Cell Biology 5, 211–215
(March 2003); doi:10.1038/ncb937
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news and views
The multiple functions of tumour suppressors: it's all in APC
Riccardo Fodde
Nature Cell Biology 5, 190–192
(March 2003); doi:10.1038/ncb0303-190
| Full Text (HTML/PDF) |
review article
ATM and related protein kinases: safeguarding genome integrity
Yosef Shiloh
Nature Reviews Cancer 3, 155–168
(March 2003); doi:10.1038/nrc1011
| Summary | Full Text (HTML / PDF) |
article
The codon 72 polymorphic variants of p53 have markedly different apoptotic potential
Patrick Dumont, J. I-Ju Leu, Anthony C. Della Pietra, III Donna L. George and Maureen Murphy
Nature Genetics 33, 357–365
(March 2003); doi:10.1038/ng1093
| Abstract | Full Text (HTML/PDF) |
February
letters to nature
Extra-embryonic function of Rb is essential for embryonic development and viability
Lizhao Wu, Alain de Bruin, Harold I. Saavedra, Maja Starovic, Anthony Trimboli, Ying Yang, Jana Opavska, Pamela Wilson, John C. Thompson, Michael C. Ostrowski, Thomas J. Rosol, Laura A. Woollett, Michael Weinstein, James C. Cross, Michael L. Robinson and Gustavo Leone
Nature 421, 942–947
(27 February 2003); doi:10.1038/nature01417
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news and views
Developmental biology: A twist in a mouse tale
Nick Dyson
Nature 421, 903–904
(27 February 2003); doi:10.1038/421903a
| Full Text (HTML / PDF) |
review article
The endothelin axis: emerging role in cancer
Joel Nelson, Anna Bagnato, Bruno Battistini and Perry Nisen
Nature Reviews Cancer 3, 110–116
(February 2003); doi:10.1038/nrc990
| Summary | Full Text (HTML / PDF) |
review article
The role of p53 in determining sensitivity to radiotherapy
Andrei V. Gudkov and Elena A. Komarova
Nature Reviews Cancer 3, 117–129
(February 2003); doi:10.1038/nrc992
| Summary | Full Text (HTML / PDF) |
letter
iASPP oncoprotein is a key inhibitor of p53 conserved from worm to human
Daniele Bergamaschi, Yardena Samuels, Nigel J. O'Neil, Giuseppe Trigiante, Tim Crook, Jung-Kuang Hsieh, Daniel J. O'Connor, Shan Zhong, Isabelle Campargue, Matthew L. Tomlinson, Patricia E. Kuwabara and Xin Lu
Nature Genetics 33, 162–167
(February 2003); doi:10.1038/ng1070
| First Paragraph | Full Text (HTML/PDF) |
letter
t(11;19)(q21;p13) translocation in mucoepidermoid carcinoma creates a novel fusion product that disrupts a Notch signaling pathway
Giovanni Tonon, Sanjay Modi, Lizi Wu, Akihito Kubo, Amy B. Coxon, Takefumi Komiya, Kevin O'Neil, Kristen Stover, Adel El-Naggar, James D. Griffin, Ilan R. Kirsch and Frederic J. Kaye
Nature Genetics 33, 208–213
(February 2003); doi:10.1038/ng1083
| First Paragraph | Full Text (HTML/PDF) |
review article
Inhibiting the p53-MDM2 interaction: an important target for cancer therapy
Patrick Chène
Nature Reviews Cancer 3, 102–109
(February 2003); doi:10.1038/nrc991
| Summary | Full Text (HTML / PDF) |
original paper
Type 1 insulin-like growth factor regulates MT1-MMP synthesis and tumor invasion via PI 3-kinase/Akt signaling
Donglei Zhang and Pnina Brodt
Oncogene 22, 974–982
(20 February 2003); doi:10.1038/sj.onc.1206197
| Abstract |
letters to nature
Structure of the extracellular region of HER2 alone and in complex with the Herceptin Fab
Hyun-Soo Cho, Karen Mason, Kasra X. Ramyar, Ann Marie Stanley, Sandra B. Gabelli, Dan W. Denney Jr and Daniel J. Leahy
Nature 421, 756–760
(13 February 2003); doi:10.1038/nature01392
| First Paragraph | Full Text (HTML / PDF) |
review article
Coordinated regulation of life and death by RB
B. Nelson Chau and Jean Y.J. Wang
Nature Reviews Cancer 3, 130–138
(February 2003); doi:10.1038/nrc993
| Summary | Full Text (HTML / PDF) |
letters to nature
NF-κB blockade and oncogenic Ras trigger invasive human epidermal neoplasia
Maya Dajee, Mirella Lazarov, Jennifer Y. Zhang, Ti Cai, Cheryl L. Green, Alan J. Russell, M. Peter Marinkovich, Shiying Tao, Qun Lin, Yoshiaki Kubo and Paul A. Khavari
Nature 421, 639–643
(06 February 2003); doi:10.1038/nature01283
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news and views
Cancer: More than skin deep
Diana Bolotin and Elaine Fuchs
Nature 421, 594–595
(06 February 2003); doi:10.1038/421594a
| Full Text (HTML / PDF) |
review article
Disruption of differentiation in human cancer: AML shows the way
Daniel G. Tenen
Nature Reviews Cancer 3, 89–101
(February 2003); doi:10.1038/nrc989
| Summary | Full Text (HTML / PDF) |
original paper
Bcl-xL and Akt cooperate to promote leukemogenesis in vivo
Robyn Karnauskas, Qun Niu, Sunit Talapatra, David R. Plas, Marianne E. Greene, John D. Crispino and Charles M. Rudin
Oncogene 22, 688–698
(6 February 2003); doi:10.1038/sj.onc.1206159
| Abstract |
January
review article
Targeting tumours with genetically enhanced T lymphocytes
Michel Sadelain, Isabelle Rivière and Renier Brentjens
Nature Reviews Cancer 3, 35–45
(January 2003); doi:10.1038/nrc971
| Summary | Full Text (HTML / PDF) |
article
A Robertsonian translocation suppresses a somatic recombination pathway to loss of heterozygosity
Kevin M. Haigis and William F. Dove
Nature Genetics 33, 33–39
(January 2003); doi:10.1038/ng1055
| Abstract | Full Text (HTML/PDF) |
news and views
Somatic recombination redux
Jay A. Tischfield and Changshun Shao
Nature Genetics 33, 5–6
(January 2003); doi:10.1038/ng0103-5
| Full Text (HTML/PDF) |
letter
Regulation of microtubule stability by the von Hippel-Lindau tumour suppressor protein pVHL
Alexander Hergovich, Joanna Lisztwan, Robert Barry, Pia Ballschmieter and Wilhelm Krek
Nature Cell Biology 5, 64–70
(January 2003); doi:10.1038/ncb899
| First Paragraph | Full Text (HTML/PDF) |
news and views
New insights into an enigmatic tumour suppressor
Peter J. Ratcliffe
Nature Cell Biology 5, 7–8
(January 2003); doi:10.1038/ncb0103-7
| Full Text (HTML/PDF) |
news and views
The nucleolus: at the stem of immortality
Rosa Bernardi and Pier Paolo Pandolfi
Nature Medicine 9, 24–25
(January 2003); doi:10.1038/nm0103-24
| Full Text (HTML/PDF) |
news and views
Predicting the future of breast cancer
Åke Borg, Mårten Fernö and Carsten Peterson
Nature Medicine 9, 16–18
(January 2003); doi:10.1038/nm0103-16
| Full Text (HTML/PDF) |
review article
Validating survivin as a cancer therapeutic target
Dario C. Altieri
Nature Reviews Cancer 3, 46–54
(January 2003); doi:10.1038/nrc968
| Summary | Full Text (HTML / PDF) |
original paper
Stat3 activation regulates the expression of vascular endothelial growth factor and human pancreatic cancer angiogenesis and metastasis
Daoyan Wei, Xiangdong Le, Leizhen Zheng, Liwei Wang, Jennifer A Frey, Allen C Gao, Zhihai Peng, Suyun Huang, Henry Q Xiong, James L Abbruzzese and Keping Xie
Oncogene 22, 319–329
(23 January 2003); doi:10.1038/sj.onc.1206122
| Abstract |
review article
Targeting RAS signalling pathways in cancer therapy
Julian Downward
Nature Reviews Cancer 3, 11–22
(January 2003); doi:10.1038/nrc969
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brief communication
High frequency of BRAF mutations in nevi
Pamela M. Pollock, Ursula L. Harper, Katherine S. Hansen, Laura M. Yudt, Mitchell Stark, Christiane M. Robbins, Tracy Y. Moses, Galen Hostetter, Urs Wagner, John Kakareka, Ghadi Salem, Tom Pohida, Peter Heenan, Paul Duray, Olli Kallioniemi, Nicholas K. Hayward, Jeffrey M. Trent and Paul S. Meltzer
Nature Genetics 33, 19–20
(January 2003); doi:10.1038/ng1054
| First Paragraph | Full Text (HTML/PDF) |
review article
The Fanconi anaemia/BRCA pathway
Alan D. D'Andrea and Markus Grompe
Nature Reviews Cancer 3, 23–34
(January 2003); doi:10.1038/nrc970
| Summary | Full Text (HTML / PDF) |
review article
Border-cell migration: The race is on
Denise J. Montell
Nature Reviews Molecular Cell Biology 4, 13–24
(January 2003); doi:10.1038/nrm1006
| Summary | Full Text (HTML / PDF) |
review article
Metastasis suppressors alter the signal transduction of cancer cells
Patricia S. Steeg
Nature Reviews Cancer 3, 55–63
(January 2003); doi:10.1038/nrc967
| Summary | Full Text (HTML / PDF) |
letter
Nf1 has an essential role in endothelial cells
Aaron D. Gitler, Yuan Zhu, Fraz A. Ismat, Min Min Lu, Yasutaka Yamauchi, Luis F. Parada and Jonathan A. Epstein
Nature Genetics 33, 75–79
(January 2003); doi:10.1038/ng1059
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news and views
Cre-constructing the heart
Pilar Ruiz-Lozano and Kenneth R. Chien
Nature Genetics 33, 8–9
(January 2003); doi:10.1038/ng0103-8
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