article Blockade of Dll4 inhibits tumour growth by promoting non-productive angiogenesis
Irene Noguera-Troise, Christopher Daly, Nicholas J. Papadopoulos, Sandra Coetzee, Pat Boland, Nicholas W. Gale, Hsin Chieh Lin, George D. Yancopoulos and Gavin Thurston Nature444, 1032–1037
(21 December 2006); doi:10.1038/nature05355
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letter Inhibition of Dll4 signalling inhibits tumour growth by deregulating angiogenesis
John Ridgway, Gu Zhang, Yan Wu, Scott Stawicki, Wei-Ching Liang, Yvan Chanthery, Joe Kowalski, Ryan J. Watts, Christopher Callahan, Ian Kasman, Mallika Singh, May Chien, Christine Tan, Jo-Anne S. Hongo, Fred de Sauvage, Greg Plowman and Minhong Yan Nature444, 1083–1087
(21 December 2006); doi:10.1038/nature05313
| First Paragraph | Full Text (HTML / PDF) |
news and analysis Panitumumab
Leonard Saltz, Chris Easley and Peter Kirkpatrick Nature Reviews Drug Discovery5, 987–988
(December 2006); doi:10.1038/nrd2204
| Summary | Full Text (HTML / PDF) |
review Targeting the Hedgehog pathway in cancer
Lee L. Rubin and Frederic J. de Sauvage Nature Reviews Drug Discovery5, 1026–1033
(December 2006); doi:10.1038/nrd2086
| Summary | Full Text (HTML / PDF) |
letter A Wnt-Axin2-GSK3β cascade regulates Snail1 activity in breast cancer cells
Jong In Yook, Xiao-Yan Li, Ichiro Ota, Casey Hu, Hyun Sil Kim, Nam Hee Kim, So Young Cha, Joo Kyung Ryu, Yoon Jung Choi, Jin Kim, Eric R. Fearon & Stephen J. Weiss Nature Cell Biology8, 1398–1406
(December 2006); doi:10.1038/ncb1508
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review Regulating the p53 pathway: in vitro hypotheses, in vivo veritas
Franck Toledo and Geoffrey M. Wahl Nature Reviews Cancer6, 906–923
(December 2006); doi:10.1038/nrc2012
| Summary | Full Text (HTML / PDF) |
letter Bone morphogenetic proteins inhibit the tumorigenic potential of human brain tumour-initiating cells
S. G. M. Piccirillo, B. A. Reynolds, N. Zanetti, G. Lamorte, E. Binda, G. Broggi, H. Brem, A. Olivi, F. Dimeco and A. L. Vescovi Nature444, 761–765
(7 December 2006); doi:10.1038/nature05349
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review Mining the Wnt pathway for cancer therapeutics
Nick Barker and Hans Clevers Nature Reviews Drug Discovery5, 997–1014
(December 2006); doi:10.1038/nrd2154
| Summary | Full Text (HTML / PDF) |
letter Tumour-mediated upregulation of chemoattractants and recruitment of myeloid cells predetermines lung metastasis
Sachie Hiratsuka, Akira Watanabe, Hiroyuki Aburatani & Yoshiro Maru Nature Cell Biology8, 1369–1375
(December 2006); doi:10.1038/ncb1507
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news and views S100 chemokines mediate bookmarking of premetastatic niches
Shahin Rafii & David Lyden Nature Cell Biology8, 1321–1323
(December 2006); doi:10.1038/ncb1206-1321
| Summary | Full Text (HTML / PDF) |
review The role of cytochrome P450 enzymes in endogenous signalling pathways and environmental carcinogenesis
Daniel W. Nebert and Timothy P. Dalton Nature Reviews Cancer6, 947–960
(December 2006); doi:10.1038/nrc2015
| Summary | Full Text (HTML / PDF) |
November
letter Mitogenic signalling and the p16INK4a-Rb pathway cooperate to enforce irreversible cellular senescence
Akiko Takahashi, Naoko Ohtani, Kimi Yamakoshi, Shin-ichi Iida, Hidetoshi Tahara, Keiko Nakayama, Keiichi I. Nakayama, Toshinori Ide, Hideyuki Saya & Eiji Hara Nature Cell Biology8, 1291–1297
(November 2006); doi:10.1038/ncb1491
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news and views ROS as a tumour suppressor?
Matthew R. Ramsey & Norman E. Sharpless Nature Cell Biology8, 1213–1215
(November 2006); doi:10.1038/ncb1106-1213
| Summary | Full Text (HTML / PDF) |
letter R-spondin1 is essential in sex determination, skin differentiation and malignancy
Pietro Parma, Orietta Radi, Valerie Vidal, Marie Christine Chaboissier, Elena Dellambra, Stella Valentini, Liliana Guerra, Andreas Schedl & Giovanna Camerino Nature Genetics38, 1304–1309
(November 2006); doi:10.1038/ng1907
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review MicroRNA signatures in human cancers
George A. Calin and Carlo M. Croce Nature Reviews Cancer6, 857–866
(November 2006); doi:10.1038/nrc1997
| Summary | Full Text (HTML / PDF) |
article Inactivation of the p53 pathway in retinoblastoma
Nikia A. Laurie, Stacy L. Donovan, Chie-Schin Shih, Jiakun Zhang, Nicholas Mills, Christine Fuller, Amina Teunisse, Suzanne Lam, Yolande Ramos, Adithi Mohan, Dianna Johnson, Matthew Wilson, Carlos Rodriguez-Galindo, Micaela Quarto, Sarah Francoz, Susan M. Mendrysa, R. Kiplin Guy, Jean-Christophe Marine, Aart G. Jochemsen and Michael A. Dyer Nature444, 61–66
(02 November 2006); doi:10.1038/nature05194
| Summary | Full Text (HTML / PDF) |
news and views Cancer biology: Second step to retinal tumours
Valerie A. Wallace Nature444, 45–46
(02 November 2006); doi:10.1038/444045a Full Text (HTML / PDF) |
review Polycomb silencers control cell fate, development and cancer
Anke Sparmann and Maarten van Lohuizen Nature Reviews Cancer6, 846–856
(November 2006); doi:10.1038/nrc1991
| Summary | Full Text (HTML / PDF) |
October
review Cysteine cathepsins: multifunctional enzymes in cancer
Mona Mostafa Mohamed and Bonnie F. Sloane Nature Reviews Cancer6, 764–775
(October 2006); doi:10.1038/nrc1949
| Summary | Full Text (HTML / PDF) |
review Ubiquitin and ubiquitin-like proteins in cancer pathogenesis
Daniela Hoeller, Christina-Maria Hecker and Ivan Dikic Nature Reviews Cancer6, 776–788
(2006); doi:10.1038/nrc1994
| Summary | Full Text (HTML / PDF) |
article Anti-oncogenic role of the endoplasmic reticulum differentially activated by mutations in the MAPK pathway
Christophe Denoyelle, George Abou-Rjaily, Vladimir Bezrookove, Monique Verhaegen, Timothy M. Johnson, Douglas R. Fullen, Jenny N. Pointer, Stephen B. Gruber, Lyndon D. Su, Mikhail A. Nikiforov, Randal J. Kaufman, Boris C. Bastian & Maria S. Soengas Nature Cell Biology8, 1053–1063
(2006); doi:10.1038/ncb1471
| Summary | Full Text (HTML / PDF) |
review Mechanisms of cutaneous toxicities to EGFR inhibitors
Mario E. Lacouture Nature Reviews Cancer6, 803–812
(October 2006); doi:10.1038/nrc1970
| Summary | Full Text (HTML / PDF) |
review Discovery and development of sorafenib: a multikinase inhibitor for treating cancer
Scott Wilhelm, Christopher Carter, Mark Lynch, Timothy Lowinger, Jacques Dumas, Roger A. Smith, Brian Schwartz, Ronit Simantov and Susan Kelley Nature Reviews Drug Discovery5, 835–844
(October 2006); doi:10.1038/nrd2130
| Summary | Full Text (HTML / PDF) |
September
review Model organisms: The mighty mouse: genetically engineered mouse models in cancer drug development
Norman E. Sharpless and Ronald A. DePinho Nature Reviews Drug Discovery7, 741–754
(September 2006); doi:10.1038/nrd2110
| Summary | Full Text (HTML / PDF) |
letter JAK signaling globally counteracts heterochromatic gene silencing
Song Shi, Healani C Calhoun, Fan Xia, Jinghong Li, Long Le & Willis X Li Nature Genetics38, 1071–1076
(2006); doi:10.1038/ng1860
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news and views A Hopscotch-chromatin connection
Aurel Betz & James E Darnell Jr Nature Genetics38, 977–979
(2006); doi:10.1038/ng0906-977
| Summary |
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August
letter Chronic stress promotes tumor growth and angiogenesis in a mouse model of ovarian carcinoma
Premal H Thaker, Liz Y Han, Aparna A Kamat, Jesusa M Arevalo, Rie Takahashi, Chunhua Lu, Nicholas B Jennings, Guillermo Armaiz-Pena, James A Bankson, Murali Ravoori, William M Merritt, Yvonne G Lin, Lingegowda S Mangala, Tae Jin Kim, Robert L Coleman, Charles N Landen, Yang Li, Edward Felix, Angela M Sanguino, Robert A Newman, Mary Lloyd, David M Gershenson, Vikas Kundra, Gabriel Lopez-Berestein, Susan K Lutgendorf, Steven W Cole & Anil K Sood Nature Medicine12, 939–954
(August 2006); doi:10.1038/nm1447
| Summary | Full Text (HTML / PDF) |
article Embryonic and tumorigenic pathways converge via Nodal signaling: role in melanoma aggressiveness
Jolanta M Topczewska, Lynne-Marie Postovit, Naira V Margaryan, Anthony Sam, Angela R Hess, William W Wheaton, Brian J Nickoloff, Jacek Topczewski & Mary J C Hendrix Nature Medicine12, 925–932
(10 August 2006); doi:10.1038/nm1448
| Summary | Full Text (HTML / PDF) |
news and views Embryogenesis meets tumorigenesis
John T Lee & Meenhard Herlyn Nature Medicine12, 882–884
(10 August 2006); doi:10.1038/nm0806-882
| Summary | Full Text (HTML / PDF) |
letter Interaction of KAI1 on tumor cells with DARC on vascular endothelium leads to metastasis suppression
Sucharita Bandyopadhyay, Rui Zhan, Asok Chaudhuri, Misako Watabe, Sudha K Pai, Shigeru Hirota, Sadahiro Hosobe, Taisei Tsukada, Kunio Miura, Yukio Takano, Ken Saito, Mary E Pauza, Sunao Hayashi, Ying Wang, Sonia Mohinta, Tomoyuki Mashimo, Megumi Iiizumi, Eiji Furuta & Kounosuke Watabe Nature Medicine12, 933–938
(10 August 2006); doi:10.1038/nm1444
| Summary | Full Text (HTML / PDF) |
news and views Stopping cancer before it colonizes
Carrie W Rinker-Schaeffer & Jonathan A Hickson Nature Medicine12, 887–888
(10 August 2006); doi:10.1038/nm0806-887
| Summary | Full Text (HTML / PDF) |
review Targeting the mechanisms of tumoral immune tolerance with small-molecule inhibitors
Alexander J. Muller and Peggy A. Scherle Nature Reviews Cancer6, 613–625
(August 2006); doi:10.1038/nrc1929
| Summary | Full Text (HTML / PDF) |
July
letter IL-23 promotes tumour incidence and growth
John L. Langowski, Xueqing Zhang, Lingling Wu, Jeanine D. Mattson, Taiying Chen, Kathy Smith, Beth Basham, Terrill McClanahan, Robert A. Kastelein and Martin Oft Nature442, 461–465
(27 July 2006); doi:10.1038/nature04808
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article E2-EPF UCP targets pVHL for degradation and associates with tumor growth and metastasis
Cho-Rok Jung, Kyung-Sun Hwang, Jinsang Yoo, Won-Kyung Cho, Jin-Man Kim, Woo Ho Kim & Dong-Soo Im Nature Medicine12, 809–816
(July 2006); doi:10.1038/nm1440
| Summary | Full Text (HTML / PDF) |
review The role of nitric oxide in tumour progression
Dai Fukumura, Satoshi Kashiwagi and Rakesh K. Jain Nature Reviews Cancer6, 521–534
(July 2006); doi:10.1038/nrc1910
| Summary | Full Text (HTML / PDF) |
letter CpG island methylator phenotype underlies sporadic microsatellite instability and is tightly associated with BRAF mutation in colorectal cancer
Daniel J Weisenberger, Kimberly D Siegmund, Mihaela Campan, Joanne Young, Tiffany I Long, Mark A Faasse, Gyeong Hoon Kang, Martin Widschwendter, Deborah Weener, Daniel Buchanan, Hoey Koh, Lisa Simms, Melissa Barker, Barbara Leggett, Joan Levine, Myungjin Kim, Amy J French, Stephen N Thibodeau, Jeremy Jass, Robert Haile & Peter W Laird Nature Genetics7, 787–793
(July 2006); doi:10.1038/ng1834
| Summary | Full Text (HTML / PDF) |
news and views CIMPle origin for promoter hypermethylation in colorectal cancer?
Kornel Schuebel, Wei Chen & Stephen B Baylin Nature Genetics7, 738–740
(July 2006); doi:10.1038/ng0706-738
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article E2-EPF UCP targets pVHL for degradation and associates with tumor growth and metastasis
Cho-Rok Jung, Kyung-Sun Hwang, Jinsang Yoo, Won-Kyung Cho, Jin-Man Kim, Woo Ho Kim & Dong-Soo Im Nature Medicine12, 755–762
(02 July 2006); doi:10.1038/nm1440
| First Paragraph | Full Text (HTML / PDF) |
review Tumour microenvironment: TGFβ: the molecular Jekyll and Hyde of cancer
Brian Bierie and Harold L. Moses Nature Reviews Cancer6, 506–520
(July 2006); doi:10.1038/nrc1926
| Summary | Full Text (HTML / PDF) |
June
review article Brain tumour stem cells
Angelo L. Vescovi, Rossella Galli and Brent A. Reynolds Nature Reviews Cancer6, 425–436
(June 2006); doi:10.1038/nrc1889
| Summary | Full Text (HTML / PDF) |
letter Smad4 signalling in T cells is required for suppression of gastrointestinal cancer
Byung-Gyu Kim, Cuiling Li, Wenhui Qiao, Mizuko Mamura, Barbara Kasperczak, Miriam Anver, Lawrence Wolfraim, Suntaek Hong, Elizabeth Mushinski, Michael Potter, Seong-Jin Kim, Xin-Yuan Fu, Chuxia Deng and John J. Letterio Nature441, 1015–1019
(22 June 2006); doi:10.1038/nature04846
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review article p21-activated kinases in cancer
Rakesh Kumar, Anupama E. Gururaj and Christopher J. Barnes Nature Reviews Cancer6, 459–471
(June 2006); doi:10.1038/nrc1892
| Summary | Full Text (HTML / PDF) |
letter CRD-BP mediates stabilization of ßTrCP1 and c-myc mRNA in response to ß-catenin signalling
Felicite K. Noubissi, Irina Elcheva, Neehar Bhatia, Abbas Shakoori, Andrei Ougolkov, Jianghuai Liu, Toshinari Minamoto, Jeff Ross, Serge Y. Fuchs and Vladimir S. Spiegelman Nature441, 898–901
(15 June 2006); doi:10.1038/nature04839
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review article Metastasis: a question of life or death
Patrick Mehlen and Alain Puisieux Nature Reviews Cancer6, 449–458
(June 2006); doi:10.1038/nrc1886
| Summary | Full Text (HTML / PDF) |
May
article Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cells
Ömer H. Yilmaz, Riccardo Valdez, Brian K. Theisen, Wei Guo, David O. Ferguson, Hong Wu and Sean J. Morrison Nature441, 475–482
(May 2006); doi:10.1038/nature04703
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letter PTEN maintains haematopoietic stem cells and acts in lineage choice and leukaemia prevention
Jiwang Zhang, Justin C. Grindley, Tong Yin, Sachintha Jayasinghe, Xi C. He, Jason T. Ross, Jeffrey S. Haug, Dawn Rupp, Kimberly S. Porter-Westpfahl, Leanne M. Wiedemann, Hong Wu and Linheng Li Nature441, 518–522
(May 2006); doi:10.1038/nature04747
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news and views Stem cells: Good, bad and reformable
Viktor Janzen & David T. Scadden Nature441,418–419
(May 2006); doi:10.1038/441418b
| Full Text (HTML / PDF) |
review article Is there more to BARD1 than BRCA1?
Irmgard Irminger-Finger and Charles Edward Jefford Nature Reviews Cancer6, 382–391
(May 2006); doi:10.1038/nrc1878
| Summary | Full Text (HTML / PDF) |
letter A truncating mutation of HDAC2 in human cancers confers resistance to histone deacetylase inhibition
Santiago Ropero, Mario F Fraga, Esteban Ballestar, Richard Hamelin, Hiroyuki Yamamoto, Manuel Boix-Chornet, Rosalia Caballero, Miguel Alaminos, Fernando Setien, Maria F Paz, Michel Herranz, Jose Palacios, Diego Arango, Torben F Orntoft, Lauri A Aaltonen, Simó Schwartz Jr & Manel Esteller Nature Genetics38, 566–569
(May 2006); doi:10.1038/ng1773
| Summary | Full Text (HTML / PDF) |
review Ubiquitin ligases: cell–cycle control and cancer
Keiichi I. Nakayama and Keiko Nakayama Nature Reviews Cancer6, 369–381
(May 2006); doi:10.1038/nrc1881
| Summary | Full Text (HTML / PDF) |
review article Notch 1 activation in the molecular pathogenesis of T-cell acute lymphoblastic leukaemia
Clemens Grabher, Harald von Boehmer and A. Thomas Look Nature Reviews Cancer6, 347–359
(May 2006); doi:10.1038/nrc1880
| Summary | Full Text (HTML / PDF) |
April
letter Lysyl oxidase is essential for hypoxia-induced metastasis
Janine T. Erler, Kevin L. Bennewith, Monica Nicolau, Nadja Dornhöfer, Christina Kong, Quynh-Thu Le, Jen-Tsan Ashley Chi, Stefanie S. Jeffrey and Amato J. Giaccia Nature440, 1222–1226
(27 April 2006); doi:10.1038/nature04695
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review article Regulatory T cells, tumour immunity and immunotherapy
Weiping Zou Nature Reviews Immunology6, 295–307
(April 2006); doi:10.1038/nri1806
| Summary | Full Text (HTML / PDF) |
review article Pregnancy-associated breast cancer and metastasis
Pepper Schedin Nature Reviews Cancer6, 281–291
(April 2006); doi:10.1038/nrc1839
| Summary | Full Text (HTML / PDF) |
article Selective cytotoxic T-lymphocyte targeting of tumor immune escape variants
Thorbald van Hall, Elisabeth Z Wolpert, Peter van Veelen, Sandra Laban, Michael van der Veer, Marjet Roseboom, Sandra Bres, Per Grufman, Arnoud de Ru, Hugo Meiring, Ad de Jong, Kees Franken, Antoinette Teixeira, Rob Valentijn, Jan Wouter Drijfhout, Frits Koning, Marcel Camps, Ferry Ossendorp, Klas Kärre, Hans-Gustaf Ljunggren, Cornelis J M Melief & Rienk Offringa Nature Medicine12, 417–424
(April 2006); doi:10.1038/nm1381
| Summary | Full Text (HTML / PDF) |
review article Protein-tyrosine phosphatases and cancer
Arne Östman, Carina Hellberg and Frank D. Böhmer Nature Reviews Cancer6, 307–320
(April 2006); doi:10.1038/nrc1837
| Summary | Full Text (HTML / PDF) |
article Slowed diffusion in tumors revealed by microfiberoptic epifluorescence photobleaching
Jay R Thiagarajah, Jung Kyung Kim, Mazin Magzoub & A S Verkman Nature Methods3, 275–280
(April 2006); doi:10.1038/nmeth863
| Summary | Full Text (HTML / PDF) |
March
letter Regulation of cancer cell migration and bone metastasis by RANKL
D. Holstead Jones , Tomoki Nakashima, Otto H. Sanchez, Ivona Kozieradzki , Svetlana V. Komarova, Ildiko Sarosi, Sean Morony, Evelyn Rubin, Renu Sarao, Carlo V. Hojilla, Vukoslav Komnenovic, Young-Yun Kong, Martin Schreiber, S. Jeffrey Dixon, Stephen M. Sims, Rama Khokha, Teiji Wada and Josef M. Penninger Nature440, 692–696
(30 March 2006); doi:10.1038/nature04524
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review article Beyond PTEN mutations: the PI3K pathway as an integrator of multiple inputs during tumorigenesis
Megan Cully , Han You, Arnold J. Levine and Tak W. Mak Nature Reviews Cancer6, 184–192
(March 2006); doi:10.1038/nrc1819
| Summary | Full Text (HTML / PDF) |
review article ASPPs and cancer
Giuseppe Trigiante and Xin Lu Nature Reviews Cancer6, 217–226
(March 2006); doi:10.1038/nrc1818
| Summary | Full Text (HTML / PDF) |
review article Targeting multidrug resistance in cancer
Gergely Szakács, Jill K. Paterson, Joseph A. Ludwig, Catherine Booth-Genthe and Michael M. Gottesman Nature Reviews Drug Discovery5, 219–234
(March 2006); doi:10.1038/nrd1984
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February
review article ASPPs and cancer
Giuseppe Trigiante and Xin Lu Nature Reviews Cancer6, 217–226
(March 2006); doi:10.1038/nrc1818
| First Paragraph | Full Text (HTML / PDF) |
article Intrinsic inhibition of transcription factor E2A by HLH proteins ABF-1 and Id2 mediates reprogramming of neoplastic B cells in Hodgkin lymphoma
Stephan Mathas, Martin Janz, Franziska Hummel, Michael Hummel, Brigitte Wollert-Wulf, Simone Lusatis, Ioannis Anagnostopoulos, Andreas Lietz, Mikael Sigvardsson, Franziska Jundt, Korinna Jöhrens, Kurt Bommert, Harald Stein and Bernd Dörken Nature Immunology7, 207–215
(February 2006); doi:10.1038/ni1285
| Abstract | Full Text (HTML/PDF) |
review article Mapping normal and cancer cell signalling networks: towards single-cell proteomics
Jonathan M. Irish, Nikesh Kotecha and Garry P. Nolan
Flow cytometry can be used to map signalling networks in individual cancer cells. This form of 'single-cell proteomics' can reveal important new information about the pathways that are activated in therapy-resistant cells and provide biomarkers for use in diagnosis and determining prognosis. Nature Reviews Cancer6, 146–155
(February 2006); doi:10.1038/nrc1804
| Summary | Full Text (HTML / PDF) |
review article Antibody targeted drugs as cancer therapeutics
David Schrama, Ralph A. Reisfeld and Jürgen C. Becker Nature Reviews Drug Discovery5, 147–159
(February 2006); doi:10.1038/nrd1957
| Summary | Full Text (HTML / PDF) |
review article Epigenetic gene silencing in cancer - a mechanism for early oncogenic pathway addiction?
Stephen B. Baylin and Joyce E. Ohm Nature Reviews Cancer6, 107–116
(February 2006); doi:10.1038/nrc1799
| Summary | Full Text (HTML / PDF) |
January
review article KLF4, p21 and context-dependent opposing forces in cancer
Benjamin D. Rowland and Daniel S. Peeper Nature Reviews Cancer6, 11–23
(January 2006); doi:10.1038/nrc1780
| Summary | Full Text (HTML / PDF) |
article Epigenetic silencers and Notch collaborate to promote malignant tumours by Rb silencing
Dolors Ferres-Marco, Irene Gutierrez-Garcia, Diana M. Vallejo, Jorge Bolivar, Francisco J. Gutierrez-Aviño and Maria Dominguez Nature439, 430–436
(26 January 2006); doi:10.1038/nature04376
| Summary | Full Text (HTML / PDF) |
letter Oncogenic pathway signatures in human cancers as a guide to targeted therapies
Andrea H. Bild, Guang Yao, Jeffrey T. Chang, Quanli Wang, Anil Potti, Dawn Chasse, Mary-Beth Joshi, David Harpole, Johnathan M. Lancaster, Andrew Berchuck, John A. Olson Jr, Jeffrey R. Marks, Holly K. Dressman, Mike West and Joseph R. Nevins Nature439, 353–357
(February 2006); doi:10.1038/nature04296
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letter BRAF mutation predicts sensitivity to MEK inhibition
David B. Solit, Levi A. Garraway, Christine A. Pratilas, Ayana Sawai, Gad Getz, Andrea Basso, Qing Ye, Jose M. Lobo, Yuhong She, Iman Osman, Todd R. Golub, Judith Sebolt-Leopold, William R. Sellers and Neal Rosen Nature439, 358–362
(February 2006); doi:10.1038/nature04304
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article A role for the scaffolding adapter GAB2 in breast cancer
Mohamed Bentires-Alj, Susana G Gil, Richard Chan, Zhigang C Wang, Yongping Wang, Naoko Imanaka, Lyndsay N Harris, Andrea Richardson, Benjamin G Neel and Haihua Gu Nature Medicine12, 114–121
(January 2006); doi:10.1038/nm1341
| Abstract | Full Text (HTML/PDF) |
letter Hypoxia-inducible factor determines sensitivity to inhibitors of mTOR in kidney cancer
George V Thomas, Chris Tran, Ingo K Mellinghoff, Derek S Welsbie, Emily Chan, Barbara Fueger, Johannes Czernin and Charles L Sawyers Nature Medicine12, 122–127
(January 2006); doi:10.1038/nm1337
| First Paragraph | Full Text (HTML/PDF) |
review article A PANorama of PAX genes in cancer and development
Ewan J. D. Robson, Shu-Jie He and Michael R. Eccles Nature Reviews Cancer6, 52–62
(January 2006); doi:10.1038/nrc1778
| Summary | Full Text (HTML / PDF) |
letter Potentiation of neuroblastoma metastasis by loss of caspase-8
Dwayne G. Stupack, Tal Teitz, Matthew D. Potter, David Mikolon, Peter J. Houghton, Vincent J. Kidd, Jill M. Lahti and David A. Cheresh Nature439, 95–99
(05 January 2006); doi:10.1038/nature04323
| First Paragraph | Full Text (HTML / PDF) |
review article The epigenetic progenitor origin of human cancer
Andrew P. Feinberg, Rolf Ohlsson and Steven Henikoff Nature Reviews Genetics7, 21–33
(January 2006); doi:10.1038/nrg1748
| Summary | Full Text (HTML / PDF) |
brief communication Conservation of gene expression signatures between zebrafish and human liver tumors and tumor progression
Siew Hong Lam, Yi Lian Wu, Vinsensius B Vega, Lance D Miller, Jan Spitsbergen, Yan Tong, Huiqing Zhan, Kunde R Govindarajan, Serene Lee, Sinnakarupan Mathavan, Karuturi R Krishna Murthy, Donald R Buhler, Edison T Liu and Zhiyuan Gong Nature Biotechnology24, 73–75
(January 2006); doi:10.1038/nbt1169
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