article Regression of abdominal aortic aneurysm by inhibition of c-Jun N-terminal kinase
Koichi Yoshimura, Hiroki Aoki, Yasuhiro Ikeda, Kozo Fujii, Norio Akiyama, Akira Furutani, Yoshinobu Hoshii, Nobuyuki Tanaka, Romeo Ricci, Tokuhiro Ishihara, Kensuke Esato, Kimikazu Hamano and Masunori Matsuzaki Nature Medicine11, 13301338
(December 2005); doi:10.1038/nm1335
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news and views Aneurysm treatments expand
Robert W Thompson Nature Medicine11, 12791281
(December 2005); doi:10.1038/nm1205-1279
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November
article Sonic hedgehog myocardial gene therapy: tissue repair through transient reconstitution of embryonic signaling
Kengo F Kusano, Roberto Pola, Toshinori Murayama, Cynthia Curry, Atsuhiko Kawamoto, Atsushi Iwakura, Satoshi Shintani, Masaaki Ii, Jun Asai, Tengiz Tkebuchava, Tina Thorne, Hideya Takenaka, Ryuichi Aikawa, David Goukassian, Patrick von Samson, Hiromichi Hamada, Young-sup Yoon, Marcy Silver, Elizabeth Eaton, Hong Ma, Lindsay Heyd, Marianne Kearney, William Munger, Jeffery A Porter, Raj Kishore and Douglas W Losordo Nature Medicine11, 11971204
(November 2005); doi:10.1038/nm1313
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review article Building the mammalian heart from two sources of myocardial cells
Margaret Buckingham, Sigolène Meilhac and Stéphane Zaffran Nature Reviews Genetics6, 826837
(November 2005); doi:10.1038/nrg1710
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October
article Adiponectin protects against myocardial ischemia-reperfusion injury through AMPK- and COX-2-dependent mechanisms
Rei Shibata, Kaori Sato, David R Pimentel, Yukihiro Takemura, Shinji Kihara, Koji Ohashi, Tohru Funahashi, Noriyuki Ouchi and Kenneth Walsh Nature Medicine11, 10961103
(October 2005); doi:10.1038/nm1295
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news and views Fat, keeping the heart healthy?
Koh-ichi Yuhki, Jun-ichi Kawabe and Fumitaka Ushikubi Nature Medicine11, 10481049
(October 2005); doi:10.1038/nm1005-1048
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September
letter The protein kinase A anchoring protein mAKAP coordinates two integrated cAMP effector pathways
Kimberly L. Dodge-Kafka, Joseph Soughayer, Genevieve C. Pare, Jennifer J. Carlisle Michel, Lorene K. Langeberg, Michael S. Kapiloff and John D. Scott Nature437, 574578
(22 September 2005); doi:10.1038/nature03966
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letter Mutations in NOTCH1 cause aortic valve disease
Vidu Garg, Alecia N. Muth, Joshua F. Ransom, Marie K. Schluterman, Robert Barnes, Isabelle N. King , Paul D. Grossfeld and Deepak Srivastava Nature437, 270274
(08 September 2005); doi:10.1038/nature03940
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August
letter Dystrophic heart failure blocked by membrane sealant poloxamer
Soichiro Yasuda, DeWayne Townsend, Daniel E. Michele, Elizabeth G. Favre, Sharlene M. Day and Joseph M. Metzger Nature436, 10251029
(18 August 2005); doi:10.1038/nature03844
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news and views Cardiology: Rips repaired
Richard A. Steinhardt Nature436, 925
(18 August 2005); doi:10.1038/436925a
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review article Leukotriene modifiers as potential therapeutics for cardiovascular disease
Colin D. Funk Nature Reviews Drug Discovery4, 664672
(August 2005); doi:10.1038/nrd1796
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July
article Serum response factor regulates a muscle-specific microRNA that targets Hand2 during cardiogenesis
Yong Zhao , Eva Samal and Deepak Srivastava Nature436, 214220
(14 July 2005); doi:10.1038/nature03817
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news and views Developmental biology: Tiny brakes for a growing heart
Benoit G. Bruneau Nature436, 181182
(14 July 2005); doi:10.1038/436181a
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May
research article Transient inhibition of BMP signaling by Noggin induces cardiomyocyte differentiation of mouse embryonic stem cells
Shinsuke Yuasa, Yuji Itabashi, Uichi Koshimizu, Tomofumi Tanaka, Keijiro Sugimura, Masayoshi Kinoshita, Fumiyuki Hattori, Shin-ichi Fukami, Takuya Shimazaki, Hideyuki Okano, Satoshi Ogawa and Keiichi Fukuda Nature Biotechnology23, 607611
(May 2005); doi:10.1038/nbt1093
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April
article Calmodulin kinase II inhibition protects against structural heart disease
Rong Zhang, Michelle S C Khoo, Yuejin Wu, Yingbo Yang, Chad E Grueter, Gemin Ni, Edward E Price, Jr. William Thiel, Silvia Guatimosim, Long-Sheng Song, Ernest C Madu, Anisha N Shah, Tatiana A Vishnivetskaya, James B Atkinson, Vsevolod V Gurevich, Guy Salama, W J Lederer, Roger J Colbran and Mark E Anderson Nature Medicine11, 409417
(April 2005); doi:10.1038/nm1215
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news and views Beyond beta blockers
Donald M Bers Nature Medicine11, 379380
(April 2005); doi:10.1038/nm0405-379
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March
article The fibrin-derived peptide Bb15-42 protects the myocardium against ischemia-reperfusion injury
Peter Petzelbauer, Paula A Zacharowski, Yasuhiro Miyazaki, Peter Friedl, Georg Wickenhauser, Francis J Castellino, Marion Gröger, Klaus Wolff and Kai Zacharowski Nature Medicine11, 298304
(March 2005); doi:10.1038/nm1198
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February
article Chronic inhibition of cyclic GMP phosphodiesterase 5A prevents and reverses cardiac hypertrophy
Eiki Takimoto, Hunter C Champion, Manxiang Li, Diego Belardi, Shuxun Ren, E Rene Rodriguez, Djahida Bedja, Kathleen L Gabrielson, Yibin Wang and David A Kass Nature Medicine11, 214222
(February 2005); doi:10.1038/nm1175
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news and views Viagra: now mending hearts
Michael E Mendelsohn Nature Medicine11, 115116
(February 2005); doi:10.1038/nm0205-115
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