Research library: Cell cycle / DNA repair
2004: December
| November
| October
| September
| August
| July
| June
| May
| April
| March
| February
| January
Other Years: 2002 | 2003 | 2005 | 2006 | 2007 | 2008
December
article
Genome-wide survey of protein kinases required for cell cycle progression
M. Bettencourt-Dias, R. Giet, R. Sinka, A. Mazumdar, W. G. Lock, F. Balloux, P. J. Zafiropoulos, S. Yamaguchi, S. Winter, R. W. Carthew, M. Cooper, D. Jones, L. Frenz and D. M. Glover
Nature 432, 980–987
(23 December 2004); doi:10.1038/nature03160
| Abstract | Full Text (HTML / PDF) |
letters to nature
Retinoblastoma promotes definitive erythropoiesis by repressing Id2 in fetal liver macrophages
Antonio Iavarone , Emerson R. King, Xu-Ming Dai, Gustavo Leone, E. Richard Stanley and Anna Lasorella
Nature 432, 1040–1045
(23 December 2004); doi:10.1038/nature03068
| First Paragraph | Full Text (HTML / PDF) |
news and views
Developmental biology: No red cell is an island
James Palis
Nature 432, 964–965
(23 December 2004); doi:10.1038/432964a
| Full Text (HTML / PDF) |
letters to nature
An endoribonuclease-prepared siRNA screen in human cells identifies genes essential for cell division
Ralf Kittler, Gabriele Putz, Laurence Pelletier, Ina Poser, Anne-Kristin Heninger, David Drechsel, Steffi Fischer, Irena Konstantinova, Bianca Habermann, Hannes Grabner, Marie-Laure Yaspo, Heinz Himmelbauer, Bernd Korn, Karla Neugebauer, Maria Teresa Pisabarro and Frank Buchholz
Nature 432, 1036–1040
(23 December 2004); doi:10.1038/nature03159
| First Paragraph | Full Text (HTML / PDF) |
news and views
Rec-ing DNA
Michelle Montoya
Nature Structural and Molecular Biology 11, 1162
(December 2004); doi:10.1038/nsmb1204-1162
| Full Text (HTML/PDF) |
letter
Cytoplasmic ubiquitin ligase KPC regulates proteolysis of p27Kip1 at G1 phase
Takumi Kamura, Taichi Hara, Masaki Matsumoto, Noriko Ishida, Fumihiko Okumura, Shigetsugu Hatakeyama, Minoru Yoshida, Keiko Nakayama and Keiichi I. Nakayama
Nature Cell Biology 6, 1229–1235
(December 2004); doi:10.1038/ncb1194
| First Paragraph | Full Text (HTML/PDF) |
news and views
A second RING to destroy p27Kip1
Ludger Hengst
Nature Cell Biology 6, 1153–1155
(December 2004); doi:10.1038/ncb1204-1153
| Full Text (HTML/PDF) |
article
Cell cycle-dependent regulation of yeast telomerase by Ku
Timothy S Fisher, Andrew K P Taggart and Virginia A Zakian
Nature Structural and Molecular Biology 11, 1198–1205
(December 2004); doi:10.1038/nsmb854
| Abstract | Full Text (HTML/PDF) |
news and views
Doing more with less in bacterial DNA repair
Geoffrey R Weller, Vicky L Brandt and David B Roth
Nature Structural and Molecular Biology 11, 1158–1159
(December 2004); doi:10.1038/nsmb1204-1158
| Full Text (HTML/PDF) |
brief communication
Intra-nuclear microtubules and a mitotic spindle orientation checkpoint
Sabina Zimmerman, Rafael R. Daga and Fred Chang
Nature Cell Biology 6, 1245–1246
(December 2004); doi:10.1038/ncb1200
| First Paragraph | Full Text (HTML/PDF) |
news and views
Tudor domains track down DNA breaks
Manuel Stucki and Stephen P. Jackson
Nature Cell Biology 6, 1150–1152
(December 2004); doi:10.1038/ncb1204-1150
| Full Text (HTML/PDF) |
review article
Meiosis: cell-cycle controls shuffle and deal
Adèle L. Marston and Angelika Amon
Nature Reviews Molecular Cell Biology 5, 983–997
(December 2004); doi:10.1038/nrm1526
| Abstract | Full Text (HTML / PDF) |
research article
Antisense and siRNA as agonists of Toll-like receptors
Sudhir Agrawal and Ekambar R Kandimalla
Nature Biotechnology 22, 1533–1537
(December 2004); doi:10.1038/nbt1042
| Abstract | Full Text (HTML/PDF) |
article
Libraries enriched for alternatively spliced exons reveal splicing patterns in melanocytes and melanomas
Akira Watahiki, Kazunori Waki, Norihito Hayatsu, Toshiyuki Shiraki, Shinji Kondo, Mari Nakamura, Daisuke Sasaki, Takahiro Arakawa, Jun Kawai, Matthias Harbers, Yoshihide Hayashizaki1 and Piero Carninci
Nature Methods 1, 233–239
(December 2004); doi:10.1038/nmeth719
| Abstract | Full Text (HTML/PDF) |
article
Autonomous regulation of the anaphase-promoting complex couples mitosis to S-phase entry
Michael Rape and Marc W. Kirschner
Nature 432, 588–595
(02 December 2004); doi:10.1038/nature03023
| Summary | Full Text (HTML / PDF) |
news and views
Cell division: The heart of the cycle
Jiri Lukas and Jiri Bartek
Nature 432, 564–567
(02 December 2004); doi:10.1038/432564a
| Full Text (HTML / PDF) |
letters to nature
Poly(ADP-ribose) is required for spindle assembly and structure
Paul Chang, Myron K. Jacobson and Timothy J. Mitchison
Nature 432, 645–649
(02 December 2004); doi:10.1038/nature03061
| First Paragraph | Full Text (HTML / PDF) |
news and views
Cytoskeleton: Spindle saga
Eric Karsenti
Nature 432, 563–564
(02 December 2004); doi:10.1038/432563a
| Full Text (HTML / PDF) |
letter
The Williams syndrome transcription factor interacts with PCNA to target chromatin remodelling by ISWI to replication foci
Raymond A. Poot, Ludmila Bozhenok, Debbie L.C. van den Berg, Søren Steffensen, Fernando Ferreira, Margaret Grimaldi, Nick Gilbert, Joao Ferreira and Patrick D. Varga-Weisz
Nature Cell Biology 6, 1236–1244
(December 2004); doi:10.1038/ncb1196
| First Paragraph | Full Text (HTML/PDF) |
November
letter
A conserved Mis12 centromere complex is linked to heterochromatic HP1 and outer kinetochore protein Zwint-1
Chikashi Obuse, Osamu Iwasaki, Tomomi Kiyomitsu, Gohta Goshima, Yusuke Toyoda and Mitsuhiro Yanagida
Nature Cell Biology 6, 1135–1141
(November 2004); doi:10.1038/ncb1187
| First Paragraph | Full Text (HTML/PDF) |
article
PML bodies control the nuclear dynamics and function of the CHFR mitotic checkpoint protein
Matthew J Daniels, Alexander Marson and Ashok R Venkitaraman
Nature Structural and Molecular Biology 11, 1114–1121
(November 2004); doi:10.1038/nsmb837
| Abstract | Full Text (HTML/PDF) |
article
Regulation of p53 activity through lysine methylation
Sergei Chuikov, Julia K. Kurash, Jonathan R. Wilson, Bing Xiao, Neil Justin, Gleb S. Ivanov, Kristine McKinney, Paul Tempst, Carol Prives, Steven J. Gamblin, Nickolai A. Barlev and Danny Reinberg
Nature 432, 353–360
(18 November 2004); doi:10.1038/nature03117
| Abstract | Full Text (HTML / PDF) |
article
Crystal structure of RecBCD enzyme reveals a machine for processing DNA breaks
Martin R. Singleton, Mark S. Dillingham, Martin Gaudier, Stephen C. Kowalczykowski and Dale B. Wigley
Nature 432, 187–193
(11 November 2004); doi:10.1038/nature02988
| Abstract | Full Text (HTML / PDF) |
news and views
DNA repair: Big engine finds small breaks
Anna Marie Pyle
Nature 432, 157–158
(11 November 2004); doi:10.1038/432157a
| Full Text (HTML / PDF) |
brief communication
Organization of a sterol-rich membrane domain by cdc15p during cytokinesis in fission yeast
Tetsuya Takeda, Toshimitsu Kawate and Fred Chang
Nature Cell Biology 6, 1142–1144
(November 2004); doi:10.1038/ncb1189
| First Paragraph | Full Text (HTML/PDF) |
letter
X-linked inheritance of Fanconi anemia complementation group B
Amom Ruhikanta Meetei, Marieke Levitus, Yutong Xue, Annette L Medhurst, Michel Zwaan, Chen Ling, Martin A Rooimans, Patrick Bier, Maureen Hoatlin, Gerard Pals, Johan P de Winter, Weidong Wang and Hans Joenje
Nature Genetics 36, 1219–1224
(November 2004); doi:10.1038/ng1458
| First Paragraph | Full Text (HTML/PDF) |
news and views
A new gene on the X involved in Fanconi anemia
Nazneen Rahman and Alan Ashworth
Nature Genetics 36, 1142–1143
(November 2004); doi:10.1038/ng1104-1142
| Full Text (HTML/PDF) |
brief communication
Constitutional aneuploidy and cancer predisposition caused by biallelic mutations in BUB1B
Sandra Hanks, Kim Coleman, Sarah Reid, Alberto Plaja, Helen Firth, David FitzPatrick, Alexa Kidd, Károly Méhes, Richard Nash, Nathanial Robin, Nora Shannon, John Tolmie, John Swansbury, Alexandre Irrthum, Jenny Douglas and Nazneen Rahman
Nature Genetics 36, 1159–1161
(November 2004); doi:10.1038/ng1449
| First Paragraph | Full Text (HTML/PDF) |
news and views
From spindle checkpoint to cancer
Christoph Lengauer and Zhenghe Wang
Nature Genetics 36, 1144–1145
(November 2004); doi:10.1038/ng1104-1144
| Full Text (HTML/PDF) |
October
letters to nature
Phosphorylation-dependent binding of mitotic cyclins to Cdc6 contributes to DNA replication control
Satoru Mimura, Takashi Seki, Seiji Tanaka and John F. X. Diffley
Nature 431, 1118–1123
(28 October 2004); doi:10.1038/nature03024
| First Paragraph | Full Text (HTML / PDF) |
letter
Targeted ubiquitination of CDT1 by the DDB1-CUL4A-ROC1 ligase in response to DNA damage
Jian Hu, Chad M. McCall, Tomohiko Ohta and Yue Xiong
Nature Cell Biology 6, 1003–1009
(October 2004); doi:10.1038/ncb1172
| First Paragraph | Full Text (HTML/PDF) |
letters to nature
DNA end resection, homologous recombination and DNA damage checkpoint activation require CDK1
Grzegorz Ira, Achille Pellicioli, Alitukiriza Balijja, Xuan Wang, Simona Fiorani, Walter Carotenuto, Giordano Liberi, Debra Bressan, Lihong Wan, Nancy M. Hollingsworth, James E. Haber and Marco Foiani
Nature 431, 1011–1017
(21 October 2004); doi:10.1038/nature02964
| First Paragraph | Full Text (HTML / PDF) |
letter
Recruitment of Xenopus Scc2 and cohesin to chromatin requires the pre-replication complex
Tatsuro S. Takahashi, Pannyun Yiu, Michael F. Chou, Steven Gygi and Johannes C. Walter
Nature Cell Biology 6, 991–996
(October 2004); doi:10.1038/ncb1177
| First Paragraph | Full Text (HTML/PDF) |
review article
Checking on DNA damage in S phase
Jiri Bartek, Claudia Lukas and Jiri Lukas
Nature Reviews Molecular Cell Biology 5, 792–804
(October 2004); doi:10.1038/nrm1493
| Abstract | Full Text (HTML / PDF) |
article
Identification of BRCA1-IRIS, a BRCA1 locus product
Wael M. ElShamy and David M. Livingston
Nature Cell Biology 6, 954–967
(October 2004); doi:10.1038/ncb1171
| Abstract | Full Text (HTML/PDF) |
news and views
Refocusing on BRCA1
Alan Ashworth
Nature Cell Biology 6, 916–917
(October 2004); doi:10.1038/ncb1004-916
| Full Text (HTML/PDF) |
letter
Hog1 mediates cell-cycle arrest in G1 phase by the dual targeting of Sic1
Xavier Escoté, Meritxell Zapater, Josep Clotet and Francesc Posas
Nature Cell Biology 6, 997–1002
(October 2004); doi:10.1038/ncb1174
| First Paragraph | Full Text (HTML/PDF) |
letters to nature
p19ARF directly and differentially controls the functions of c-Myc independently of p53
Ying Qi, Mark A. Gregory, Zhaoliang Li, Jeffrey P. Brousal, Kimberly West and Stephen R. Hann
Nature 431, 712–717
(07 October 2004); doi:10.1038/nature02958
| First Paragraph | Full Text (HTML / PDF) |
article
A new effector pathway links ATM kinase with the DNA damage response
Constantinos Demonacos, Marija Krstic-Demonacos, Linda Smith, Danmei Xu, Darran P. O'Connor, Martin Jansson and Nicholas B. La Thangue
Nature Cell Biology 6, 968–976
(October 2004); doi:10.1038/ncb1170
| Abstract | Full Text (HTML/PDF) |
news and views
Crossing the tracks
Jon Reynolds
Nature Cell Biology 6, 915
(October 2004); doi:10.1038/ncb1004-915
| Full Text (HTML/PDF) |
perspectives
Opinion: Hallmarks of 'BRCAness' in sporadic cancers
Nicholas Turner, Andrew Tutt and Alan Ashworth
Nature Reviews Cancer 4, 814–819
(October 2004); doi:10.1038/nrc1457
| Abstract | Full Text (HTML / PDF) |
review article
Genetic predisposition to cancer — insights from population genetics
Steven A. Frank
Nature Reviews Genetics 5, 764–772
(October 2004); doi:10.1038/nrg1450
| Abstract | Full Text (HTML / PDF) |
September
letter
Centrosome-associated Chk1 prevents premature activation of cyclin-B-Cdk1 kinase
Alwin Krämer, Niels Mailand, Claudia Lukas, Randi G. Syljuåsen, Christopher J. Wilkinson, Erich A. Nigg, Jiri Bartek and Jiri Lukas
Nature Cell Biology 6, 884–891
(September 2004); doi:10.1038/ncb1165
| First Paragraph | Full Text (HTML/PDF) |
review article
The SCF ubiquitin ligase: insights into a molecular machine
Timothy Cardozo and Michele Pagano
Nature Reviews Molecular Cell Biology 5, 739–751
(September 2004); doi:10.1038/nrm1471
| Abstract | Full Text (HTML / PDF) |
perspectives
Opinion: Transcription — guarding the genome by sensing DNA damage
Mats Ljungman and David P. Lane
Nature Reviews Cancer 4, 727–737
(September 2004); doi:10.1038/nrc1435
| Abstract | Full Text (HTML / PDF) |
letters to nature
A microtubule-binding myosin required for nuclear anchoring and spindle assembly
Kari L. Weber, Anna M. Sokac , Jonathan S. Berg, Richard E. Cheney and William M. Bement
Nature 431, 325–329
(16 September 2004); doi:10.1038/nature02834
| First Paragraph | Full Text (HTML / PDF) |
news and views
Cell biology: Myosins meet microtubules
Margaret A. Titus
Nature 431, 252–253
(16 September 2004); doi:10.1038/431252a
| Full Text (HTML / PDF) |
article
Dynactin is involved in a checkpoint to monitor cell wall synthesis in Saccharomyces cerevisiae
Masaya Suzuki, Ryoji Igarashi, Mizuho Sekiya, Takahiko Utsugi, Shinichi Morishita, Masashi Yukawa and Yoshikazu Ohya
Nature Cell Biology 6, 861–871
(September 2004); doi:10.1038/ncb1162
| Abstract | Full Text (HTML/PDF) |
news and views
A new checkpoint takes shape
M. Andrew Hoyt
Nature Cell Biology 6, 801–803
(September 2004); doi:10.1038/ncb0904-801
| Full Text (HTML/PDF) |
news and views
Spindle checkpoint protein links Rb pathway to aneuploidy
Bernd Pulverer
Nature Cell Biology 6, 806
(September 2004); doi:10.1038/ncb0904-806
| Full Text (HTML/PDF) |
review article
BRCA1 and BRCA2: 1994 and beyond
Steven A. Narod and William D. Foulkes
Nature Reviews Cancer 4, 665–676
(September 2004); doi:10.1038/nrc1431
| Abstract | Full Text (HTML / PDF) |
review article
Apoptosis and genomic instability
Boris Zhivotovsky and Guido Kroemer
Nature Reviews Molecular Cell Biology 5, 752–762
(September 2004); doi:10.1038/nrm1443
| Summary | Full Text (HTML / PDF) |
August
letters to nature
Separase-mediated cleavage of cohesin at interphase is required for DNA repair
Koji Nagao, Yoh Adachi and Mitsuhiro Yanagida
Nature 430, 1044–1048
(26 August 2004); doi:10.1038/nature02803
| First Paragraph | Full Text (HTML / PDF) |
research article
Caged phosphopeptides reveal a temporal role for 14-3-3 in G1 arrest and S-phase checkpoint function
Anhco Nguyen, Deborah M Rothman, Justine Stehn, Barbara Imperiali and Michael B Yaffe
Nature Biotechnology 22, 993–1000
(August 2004); doi:10.1038/nbt997
| Abstract | Full Text (HTML/PDF) |
letters to nature
Cell cycle regulation of central spindle assembly
Masanori Mishima, Visnja Pavicic, Ulrike Grüneberg, Erich A. Nigg and Michael Glotzer
Nature 430, 908–913
(19 August 2004); doi:10.1038/nature02767
| First Paragraph | Full Text (HTML / PDF) |
news and views
Cell division: Timing the machine
Bruce Bowerman
Nature 430, 840–842
(19 August 2004); doi:10.1038/430840a
| Full Text (HTML / PDF) |
article
Periodic gene expression program of the fission yeast cell cycle
Gabriella Rustici, Juan Mata, Katja Kivinen, Pietro Lió, Christopher J Penkett, Gavin Burns, Jacqueline Hayles, Alvis Brazma, Paul Nurse and Jürg Bähler
Nature Genetics 36, 809–817
(August 2004); doi:10.1038/ng1377
| Abstract | Full Text (HTML/PDF) |
news and views
STARTing to recycle
Gavin Sherlock
Nature Genetics 36, 795–796
(August 2004); doi:10.1038/ng0804-795
| Full Text (HTML/PDF) |
letters to nature
Rb inactivation promotes genomic instability by uncoupling cell cycle progression from mitotic control
Eva Hernando, Zaher Nahlé , Gloria Juan, Elena Diaz-Rodriguez, Miguel Alaminos, Michael Hemann, Loren Michel, Vivek Mittal, William Gerald, Robert Benezra, Scott W. Lowe and Carlos Cordon-Cardo
Nature 430, 797–802
(12 August 2004); doi:10.1038/nature02820
| First Paragraph | Full Text (HTML / PDF) |
article
DNA binding and nucleotide flipping by the human DNA repair protein AGT
Douglas S Daniels, Tammy T Woo, Kieu X Luu, David M Noll, Neil D Clarke, Anthony E Pegg and John A Tainer
Nature Structural and Molecular Biology 11, 714–720
(August 2004); doi:10.1038/nsmb791
| Abstract | Full Text (HTML/PDF) |
news and views
Reversing DNA damage with a directional bias
Thomas J Begley and Leona D Samson
Nature Structural and Molecular Biology 11, 688–690
(August 2004); doi:10.1038/nsmb0804-688
| Full Text (HTML/PDF) |
letters to nature
Sirtuin activators mimic caloric restriction and delay ageing in metazoans
Jason G. Wood, Blanka Rogina, Siva Lavu, Konrad Howitz, Stephen L. Helfand, Marc Tatar and David Sinclair
Nature 430, 686–689
(05 August 2004); doi:10.1038/nature02789
| First Paragraph | Full Text (HTML / PDF) |
letter
The CDC-14 phosphatase controls developmental cell-cycle arrest in C. elegans
R. Mako Saito, Audrey Perreault, Bethan Peach, John S. Satterlee and Sander van den Heuvel
Nature Cell Biology 6, 777–783
(August 2004); doi:10.1038/ncb1154
| First Paragraph | Full Text (HTML/PDF) |
news and views
Developmental quiescence: Cdc14 moonlighting in G1
Edward T. Kipreos
Nature Cell Biology 6, 693–695
(August 2004); doi:10.1038/ncb0804-693
| Full Text (HTML/PDF) |
July
letter
Proteolysis-independent regulation of the transcription factor Met4 by a single Lys 48-linked ubiquitin chain
Karin Flick, Ikram Ouni, James A. Wohlschlegel, Chrissy Capati, W. Hayes McDonald, John R. Yates 3rd and Peter Kaiser
Nature Cell Biology 6, 634–641
(July 2004); doi:10.1038/ncb1143
| First Paragraph | Full Text (HTML/PDF) |
news and views
Ubiquitin signalling: what's in a chain?
Mark Hochstrasser
Nature Cell Biology 6, 571–572
(July 2004); doi:10.1038/ncb0704-571
| Full Text (HTML/PDF) |
letter
BubR1 insufficiency causes early onset of aging-associated phenotypes and infertility in mice
Darren J Baker, Karthik B Jeganathan, J Douglas Cameron, Michael Thompson, Subhash Juneja, Alena Kopecka, Rajiv Kumar, Robert B Jenkins, Piet C de Groen, Patrick Roche and Jan M van Deursen
Nature Genetics 36, 744–749
(July 2004); doi:10.1038/ng1382
| First Paragraph | Full Text (HTML/PDF) |
news and views
Aging counts on chromosomes
Oscar Fernandez-Capetillo and André Nussenzweig
Nature Genetics 36, 672–674
(July 2004); doi:10.1038/ng0704-672
| Full Text (HTML/PDF) |
letter
ATR and ATM regulate the timing of DNA replication origin firing
David Shechter, Vincenzo Costanzo and Jean Gautier
Nature Cell Biology 6, 648–655
(July 2004); doi:10.1038/ncb1145
| First Paragraph | Full Text (HTML/PDF) |
news and views
Sleeping policemen for DNA replication?
Daniel Fisher and Marcel Méchali
Nature Cell Biology 6, 576–577
(July 2004); doi:10.1038/ncb0704-576
| Full Text (HTML/PDF) |
article
TFIIH contains a PH domain involved in DNA nucleotide excision repair
Virginie Gervais, Valérie Lamour, Anass Jawhari, Florent Frindel, Emeric Wasielewski, Sandy Dubaele, Jean-Marc Egly, Jean-Claude Thierry, Bruno Kieffer and Arnaud Poterszman
Nature Structural and Molecular Biology 11, 616–622
(July 2004); doi:10.1038/nsmb782
| Abstract | Full Text (HTML/PDF) |
news and views
Transcription meets DNA repair at a PH domain
Kon Yew Kwek, William O'Gorman and Alexandre Akoulitchev
Nature Structural and Molecular Biology 11, 588–589
(July 2004); doi:10.1038/nsmb0704-588
| Full Text (HTML/PDF) |
letters to nature
Cyclin-dependent kinases regulate the antiproliferative function of Smads
Isao Matsuura , Natalia G. Denissova , Guannan Wang , Dongming He , Jianyin Long and Fang Liu
Nature 430, 226–231
(08 July 2004); doi:10.1038/nature02650
| First Paragraph | Full Text (HTML / PDF) |
letter
Centriolar SAS-5 is required for centrosome duplication in C. elegans
Marie Delattre, Sebastian Leidel, Khursheed Wani, Karine Baumer, Jeannine Bamat, Heinke Schnabel, Richard Feichtinger, Ralf Schnabel and Pierre Gönczy
Nature Cell Biology 6, 656–664
(July 2004); doi:10.1038/ncb1146
| First Paragraph | Full Text (HTML/PDF) |
news and views
Uncoiling centriole duplication
Bruce Nash and Bruce Bowerman
Nature Cell Biology 6, 573–575
(July 2004); doi:10.1038/ncb0704-573
| Full Text (HTML/PDF) |
letter
Identification of TFB5, a new component of general transcription and DNA repair factor IIH
Jeffrey A Ranish, Steven Hahn, Yu Lu, Eugene C Yi, Xiao-jun Li, Jimmy Eng and Ruedi Aebersold
Nature Genetics 36, 707–713
(July 2004); doi:10.1038/ng1385
| First Paragraph | Full Text (HTML/PDF) |
letter
A new, tenth subunit of TFIIH is responsible for the DNA repair syndrome trichothiodystrophy group A
Giuseppina Giglia-Mari, Frederic Coin, Jeffrey A Ranish, Deborah Hoogstraten, Arjan Theil, Nils Wijgers, Nicolaas G J Jaspers, Anja Raams, Manuela Argentini, P J van der Spek, Elena Botta, Miria Stefanini, Jean-Marc Egly, Ruedi Aebersold, Jan H J Hoeijmakers and Wim Vermeulen
Nature Genetics 36, 714–719
(July 2004); doi:10.1038/ng1387
| First Paragraph | Full Text (HTML/PDF) |
news and views
From proteomics to disease
Kenneth H Kraemer
Nature Genetics 36, 677–678
(July 2004); doi:10.1038/ng0704-677
| Full Text (HTML/PDF) |
June
letters to nature
Gene regulation and DNA damage in the ageing human brain
Tao Lu, Ying Pan, Shyan-Yuan Kao, Cheng Li, Isaac Kohane, Jennifer Chan and Bruce A. Yankner
Nature 429, 883–891
(24 June 2004); doi:10.1038/nature02661
| First Paragraph | Full Text (HTML / PDF) |
letters to nature
Plant retinoblastoma homologues control nuclear proliferation in the female gametophyte
Chantal Ebel, Luisa Mariconti and Wilhelm Gruissem
Nature 429, 776–780
(17 June 2004); doi:10.1038/nature02637
| First Paragraph | Full Text (HTML / PDF) |
news and views
Cdc14 phosphatase resolves the rDNA segregation delay
Gislene Pereira and Elmar Schiebel
Nature Cell Biology 6, 473–475
(June 2004); doi:10.1038/ncb0604-473
| Full Text (HTML/PDF) |
review article
Polo-like kinases and the orchestration of cell division
Francis A. Barr, Herman H. W. Silljé and Erich A. Nigg
Nature Reviews Molecular Cell Biology 5, 429–441
(June 2004); doi:10.1038/nrm1401
| Abstract | Full Text (HTML / PDF) |
May
letters to nature
Premature ageing in mice expressing defective mitochondrial DNA polymerase
Aleksandra Trifunovic, Anna Wredenberg, Maria Falkenberg, Johannes N. Spelbrink, Anja T. Rovio, Carl E. Bruder, Mohammad Bohlooly-Y, Sebastian Gidlöf, Anders Oldfors, Rolf Wibom, Jan Törnell, Howard T. Jacobs and Nils-Göran Larsson
Nature 429, 417–423
(27 May 2004); doi:10.1038/nature02517
| First Paragraph | Full Text (HTML / PDF) |
news and views
Ageing: Mice and mitochondria
George M. Martin and Lawrence A. Loeb
Nature 429, 357–359
(27 May 2004); doi:10.1038/429357a
| Full Text (HTML / PDF) |
letters to nature
Human meiotic recombinase Dmc1 promotes ATP-dependent homologous DNA strand exchange
Michael G. Sehorn, Stefan Sigurdsson, Wendy Bussen, Vinzenz M. Unger and Patrick Sung
Nature 429, 433–437
(27 May 2004); doi:10.1038/nature02563
| First Paragraph | Full Text (HTML / PDF) |
review article
A means to a DNA end: the many roles of Ku
Jessica A. Downs and Stephen P. Jackson
Nature Reviews Molecular Cell Biology 5, 367–378
(May 2004); doi:10.1038/nrm1367
| Abstract | Full Text (HTML / PDF) |
article
53BP1 links DNA damage-response pathways to immunoglobulin heavy chain class-switch recombination
John P Manis, Julio C Morales, Zhenfang Xia, Jeffery L Kutok, Frederick W Alt and Phillip B Carpenter
Nature Immunology 5, 481–487
(May 2004); doi:10.1038/ni1067
| Abstract | Full Text (HTML/PDF) |
news and views
Paradigm switching in the germinal center
Jennifer E Posey, Vicky L Brandt and David B Roth
Nature Immunology 5, 476–477
(May 2004); doi:10.1038/ni0504-476
| Full Text (HTML/PDF) |
review article
RAS and RHO GTPases in G1-phase cell-cycle regulation
Mathew L. Coleman, Christopher J. Marshall and Michael F. Olson
Nature Reviews Molecular Cell Biology 5, 355–366
(May 2004); doi:10.1038/nrm1365
| Abstract | Full Text (HTML / PDF) |
news and views feature
Ageing and the mystery at Arles
Shino Nemoto and Toren Finkel
Nature 429, 149–152
(13 May 2004); doi:10.1038/429149a
| Full Text (HTML / PDF) |
article
The Bardet-Biedl protein BBS4 targets cargo to the pericentriolar region and is required for microtubule anchoring and cell cycle progression
Jun Chul Kim, Jose L Badano, Sonja Sibold, Muneer A Esmail, Josephine Hill, Bethan E Hoskins, Carmen C Leitch, Kerrie Venner, Stephen J Ansley, Alison J Ross, Michel R Leroux, Nicholas Katsanis and Philip L Beales
Nature Genetics 36, 462–470
(May 2004); doi:10.1038/ng1352
| Abstract | Full Text (HTML/PDF) |
letters to nature
The ubiquitin ligase COP1 is a critical negative regulator of p53
David Dornan, Ingrid Wertz, Harumi Shimizu, David Arnott, Gretchen D. Frantz, Patrick Dowd, Karen O' Rourke, Hartmut Koeppen and Vishva M. Dixit
Nature 429, 86–92
(06 May 2004); doi:10.1038/nature02514
| First Paragraph | Full Text (HTML / PDF) |
letter
In vivo self-renewing divisions of haematopoietic stem cells are increased in the absence of the early G1-phase inhibitor, p18INK4C
Youzhong Yuan, Hongmei Shen, David S. Franklin, David T. Scadden and Tao Cheng
Nature Cell Biology 6, 436–442
(May 2004); doi:10.1038/ncb1126
| First Paragraph | Full Text (HTML/PDF) |
April
review article
Cell-cycle progression and the gerneration of asymmetry in Caulobacter Crescentus
Jeffrey M. Skerker & Michael T. Laub
Nature Reviews Microbiology 2, 325–337
(April 2004); doi:10.1038/nrmicro864
| Abstract | Full Text (HTML / PDF) |
letter
Dynamin 2 binds γ-tubulin and participates in centrosome cohesion
Heather M. Thompson, Hong Cao, Jing Chen, Ursula Euteneuer and Mark A. McNiven
Nature Cell Biology 6, 335–342
(April 2004); doi:10.1038/ncb1112
| First Paragraph | Full Text (HTML/PDF) |
review article
Tracing the network connecting brca and fanconi anaemia proteins
Ashok R. Venkitaraman
Nature Reviews Cancer 4, 266–276
(April 2004); doi:10.1038/nrc1321
| Abstract | Full Text (HTML / PDF) |
letters to nature
Cdc42 and mDia3 regulate microtubule attachment to kinetochores
Shingo Yasuda, Fabian Oceguera-Yanez, Takayuki Kato, Muneo Okamoto, Shigenobu Yonemura, Yasuhiko Terada, Toshimasa Ishizaki and Shuh Narumiya
Nature 428, 767–771
(15 April 2004); doi:10.1038/nature02452
| First Paragraph | Full Text (HTML / PDF) |
article
The Mad2 spindle checkpoint protein has two distinct natively folded states
Xuelian Luo, Zhanyun Tang, Guohong Xia, Katja Wassmann, Tomohiro Matsumoto, Josep Rizo and Hongtao Yu
Nature Structural and Molecular Biology 11, 338–345
(April 2004); doi:10.1038/nsmb748
| Abstract | Full Text (HTML/PDF) |
March
letter
Correcting improper chromosome-spindle attachments during cell division
Michael A. Lampson, Kishore Renduchitala, Alexey Khodjakov and Tarun M. Kapoor
Nature Cell Biology 6, 232–237
(March 2004); doi:10.1038/ncb1102
| First Paragraph | Full Text (HTML/PDF) |
news and views
Correcting SYNful attachments
Sue Biggins
Nature Cell Biology 6, 181–183
(March 2004); doi:10.1038/ncb0304-181
| Full Text (HTML/PDF) |
letter
Non-proteolytic inactivation of geminin requires CDK-dependent ubiquitination
Anatoliy Li and J. Julian Blow
Nature Cell Biology 6, 260–267
(March 2004); doi:10.1038/ncb1100
| First Paragraph | Full Text (HTML/PDF) |
article
VX-680, a potent and selective small-molecule inhibitor of the Aurora kinases, suppresses tumor growth in vivo
Elizabeth A Harrington, David Bebbington, Jeff Moore, Richele K Rasmussen, Abi O Ajose-Adeogun, Tomoko Nakayama, Joanne A Graham, Cecile Demur, Thierry Hercend, Anita Diu-Hercend, Michael Su, Julian M C Golec and Karen M Miller
Nature Medicine 10, 262–267
(March 2004); doi:10.1038/nm1003
| Abstract | Full Text (HTML/PDF) |
news and views
Aurora kinases dawn as cancer drug targets
Edward A Sausville
Nature Medicine 10, 234–235
(March 2004); doi:10.1038/nm0304-234
| Full Text (HTML/PDF) |
letters to nature
Control of the SCFSkp2-Cks1 ubiquitin ligase by the APC/CCdh1 ubiquitin ligase
Tarig Bashir, N. Valerio Dorrello, Virginia Amador, Daniele Guardavaccaro and Michele Pagano
Nature 428, 190–193
(11 March 2004); doi:10.1038/nature02330
| First Paragraph | Full Text (HTML / PDF) |
letters to nature
Degradation of the SCF component Skp2 in cell-cycle phase G1 by the anaphase-promoting complex
Wenyi Wei, Nagi G. Ayad, Yong Wan, Guo-Jun Zhang, Marc W. Kirschner and William G. Kaelin Jr
Nature 428, 194–198
(11 March 2004); doi:10.1038/nature02381
| First Paragraph | Full Text (HTML / PDF) |
review article
Targeting the checkpoint kinases: chemosensitization versus chemoprotection
Bin-Bing S. Zhou and Jiri Bartek
Nature Reviews Cancer 4, 216–225
(March 2004); doi:10.1038/nrc1296
| Abstract | Full Text (HTML / PDF) |
research article
Probing the precision of the mitotic clock with a live-cell fluorescent biosensor
Joshua T Jones, Jason W Myers, James E Ferrell and Jr Tobias Meyer
Nature Biotechnology 22, 306–312
(March 2004); doi:10.1038/nbt941
| Abstract | Full Text (HTML/PDF) |
news and views
The pulse of mitosis
Conly L Rieder and Alexei Mikhailov
Nature Biotechnology 22, 279–280
(March 2004); doi:10.1038/nbt0304-279
| Full Text (HTML/PDF) |
letters to nature
Inactivation of hCDC4 can cause chromosomal instability
Harith Rajagopalan, Prasad V. Jallepalli, Carlo Rago, Victor E. Velculescu, Kenneth W. Kinzler, Bert Vogelstein and Christoph Lengauer
Nature 428, 77–81
(04 March 2004); doi:10.1038/nature02313
| First Paragraph | Full Text (HTML / PDF) |
article
MKK7 couples stress signalling to G2/M cell-cycle progression and cellular senescence
Teiji Wada, Nicholas Joza, Hai-ying M. Cheng, Takehiko Sasaki, Ivona Kozieradzki, Kurt Bachmaier, Toshiaki Katada, Martin Schreiber, Erwin F. Wagner, Hiroshi Nishina and Josef M. Penninger
Nature Cell Biology 6, 215–226
(March 2004); doi:10.1038/ncb1098
| Abstract | Full Text (HTML/PDF) |
February
letters to nature
Direct interaction of geminin and Six3 in eye development
Filippo Del Bene, Kristin Tessmar-Raible and Joachim Wittbrodt
Nature 427, 745–749
(19 February 2004); doi:10.1038/nature02292
| First Paragraph | Full Text (HTML / PDF) |
letters to nature
The cell-cycle regulator geminin inhibits Hox function through direct and polycomb-mediated interactions
Lingfei Luo, Xiaoping Yang, Yoshihiro Takihara, Hendrik Knoetgen and Michael Kessel
Nature 427, 749–753
(19 February 2004); doi:10.1038/nature02305
| First Paragraph | Full Text (HTML / PDF) |
news and views
Transcription: Origins of licensing control
Xue Li and Michael G. Rosenfeld
Nature 427, 687–688
(19 February 2004); doi:10.1038/427687a
| Full Text (HTML / PDF) |
letter
The tumour suppressor RASSF1A regulates mitosis by inhibiting the APC-Cdc20 complex
Min Sup Song, Su Jeong Song, Nagi G. Ayad, Jin Sook Chang, Joo Hyun Lee, Hyun Kyung Hong, Ho Lee, Naeyun Choi, Jhingook Kim, Hojoong Kim, Jin Woo Kim, Eui-Ju Choi, Marc W. Kirschner and Dae-Sik Lim
Nature Cell Biology 6, 129–137
(February 2004); doi:10.1038/ncb1091
| First Paragraph | Full Text (HTML/PDF) |
news and views
Security measures at the nuclear pore
Alison Schuldt
Nature Cell Biology 6, 91
(February 2004); doi:10.1038/ncb0204-91
| Full Text (HTML/PDF) |
letter
The DNA damage checkpoint and PKA pathways converge on APC substrates and Cdc20 to regulate mitotic progression
Jennifer S. Searle, Kaila L. Schollaert, Benjamin J. Wilkins and Yolanda Sanchez
Nature Cell Biology 6, 138–145
(February 2004); doi:10.1038/ncb1092
| First Paragraph | Full Text (HTML/PDF) |
letters to nature
Dephosphorylated SRp38 acts as a splicing repressor in response to heat shock
Robert O. Blaustein and Christopher Miller
Nature 427, 499–500
(05 February 2004); doi:10.1038/427499a
| Abstract | Full Text (HTML / PDF) |
January
letter
Late-G1 cyclin-CDK activity is essential for control of cell morphogenesis in budding yeast
Jason Moffat and Brenda Andrews
Nature Cell Biology 6, 59–66
(January 2004); doi:10.1038/ncb1078
| First Paragraph | Full Text (HTML/PDF) |
article
Gadd45β is important for perpetuating cognate and inflammatory signals in T cells
Binfeng Lu, Anthony F Ferrandino and Richard A Flavell
Nature Immunology 5, 38–44
(January 2004); doi:10.1038/ni1020
| Abstract | Full Text (HTML/PDF) |
letter
Polycomb CBX7 has a unifying role in cellular lifespan
Jesús Gil, David Bernard, Dolores Martínez and David Beach
Nature Cell Biology 6, 67–72
(January 2004); doi:10.1038/ncb1077
| First Paragraph | Full Text (HTML/PDF) |
article
High expression of active CDK6 in the cytoplasm of CD8 memory cells favors rapid division
Henrique Veiga-Fernandes and Benedita Rocha
Nature Immunology 5, 31–37
(January 2004); doi:10.1038/ni1015
| Abstract | Full Text (HTML/PDF) |
news and views
Taking Drosophila Rad51 for a SPiN
Sarah J Radford & Jeff J Sekelsky
Nature Structural and Molecular Biology 11, 9–10
(January 2004); doi:10.1038/nsmb0104-9
| Abstract
| Full Text
(HTML/PDF) |
|
