news and analysis Panitumumab
Leonard Saltz, Chris Easley and Peter Kirkpatrick Nature Reviews Drug Discovery5, 987–988
(December 2006); doi:10.1038/nrd2204
| Summary | Full Text (HTML / PDF) |
review Targeting the Hedgehog pathway in cancer
Lee L. Rubin and Frederic J. de Sauvage Nature Reviews Drug Discovery5, 1026–1033
(December 2006); doi:10.1038/nrd2086
| Summary | Full Text (HTML / PDF) |
letter Inhibition of cytohesins by SecinH3 leads to hepatic insulin resistance
Markus Hafner, Anton Schmitz, Imke Grüne, Seergazhi G. Srivatsan, Bianca Paul, Waldemar Kolanus, Thomas Quast, Elisabeth Kremmer, Inga Bauer and Michael Famulok Nature444, 941–944
(14 December 2006); doi:10.1038/nature05415
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news and views Diabetes: Kicking off the insulin cascade
Catherine Jackson Nature444, 833–834
(14 December 2006); doi:10.1038/444833a
| Summary | Full Text (HTML / PDF) |
letter Long-lasting arrest of murine polycystic kidney disease with CDK inhibitor roscovitine
Nikolay O. Bukanov, Laurie A. Smith, Katherine W. Klinger, Steven R. Ledbetter and Oxana Ibraghimov-Beskrovnaya Nature444, 949–952
(14 December 2006); doi:10.1038/nature05348
| First Paragraph | Full Text (HTML / PDF) |
opinion How many drug targets are there?
John P. Overington, Bissan Al-Lazikani and Andrew L. Hopkins Nature Reviews Drug Discovery5, 993–996
(December 2006); doi:10.1038/nrd2199
| Summary | Full Text (HTML / PDF) |
review Axonal conduction and injury in multiple sclerosis: the role of sodium channels
Stephen G. Waxman Nature Reviews Neuroscience7, 932–941
(December 2006); doi:10.1038/nrn2023
| Summary | Full Text (HTML / PDF) |
review Genetics of autoimmune diseases — disorders of immune homeostasis
Peter K. Gregersen and Timothy W. Behrens Nature Reviews Genetics7, 917–928
(December 2006); doi:10.1038/nrg1944
| Summary | Full Text (HTML / PDF) |
review Mining the Wnt pathway for cancer therapeutics
Nick Barker and Hans Clevers Nature Reviews Drug Discovery5, 997–1014
(December 2006); doi:10.1038/nrd2154
| Summary | Full Text (HTML / PDF) |
November
review The obesity pipeline: current strategies in the development of anti-obesity drugs
Dunstan Cooke and Steve Bloom Nature Revies Drug Discovery5, 919–931
(November 2006); doi:10.1038/nrd2159
| Summary | Full Text (HTML / PDF) |
review Apoptosis and caspases regulate death and inflammation in sepsis
Richard S. Hotchkiss and Donald W. Nicholson Nature Reviews Immunology6, 813–822
(November 2006); doi:10.1038/nri1943
| Summary | Full Text (HTML / PDF) |
article Activated protein C inhibits tissue plasminogen activator-induced brain hemorrhage
Tong Cheng, Anthony L Petraglia, Zhang Li, Meenakshisundaram Thiyagarajan, Zhihui Zhong, Zhenhua Wu, Dong Liu, Sanjay B Maggirwar, Rashid Deane, José A Fernández, Barbra LaRue, John H Griffin, Michael Chopp & Berislav V Zlokovic Nature Medicine12, 1278–1285
(November 2006); doi:10.1038/nm1498
| Summary | Full Text (HTML / PDF) |
brief communication The gene encoding R-spondin 4 (RSPO4), a secreted protein implicated in Wnt signaling, is mutated in inherited anonychia
Diana C Blaydon, Yoshiyuki Ishii, Edel A O'Toole, Harriet C Unsworth, Muy-Teck Teh, Franz Rüschendorf, Claire Sinclair, Väinö K Hopsu-Havu, Nicholas Tidman, Celia Moss, Rosemarie Watson, David de Berker, Muhammad Wajid, Angela M Christiano & David P Kelsell Nature Genetics38, 1245–1247
(November 2006); doi:10.1038/ng1883
| Summary | Full Text (HTML / PDF) |
review MicroRNA signatures in human cancers
George A. Calin and Carlo M. Croce Nature Reviews Cancer6, 857–866
(November 2006); doi:10.1038/nrc1997
| Summary | Full Text (HTML / PDF) |
review PI3K γ inhibition: towards an 'aspirin of the 21st century'?
Thomas Rückle, Matthias K. Schwarz and Christian Rommel Nature Reviews Drug Discovery6, 903–918
(November 2006); doi:10.1038/nrd2145
| Summary | Full Text (HTML / PDF) |
October
review Novel pharmacological targets for the treatment of Parkinson's disease
Anthony H. V. Schapira , Erwan Bezard, Jonathan Brotchie, Frédéric Calon, Graham L. Collingridge, Borris Ferger, Bastian Hengerer, Etienne Hirsch , Peter Jenner, Nicolas Le Novère, José A. Obeso, Michael A. Schwarzschild, Umberto Spampinato and Giora Davidai Nature Reviews Drug Discovery5, 845–854
(October 2006); doi:10.1038/nrd2087
| Summary | Full Text (HTML / PDF) |
article State-based discovery: a multidimensional screen for small-molecule modulators of EGF signaling
Mark Sevecka & Gavin MacBeath Nature Methods5, 825–831
(October 2006); doi:10.1038/nmeth931
| Summary | Full Text (HTML / PDF) |
letter LEF-1 is crucial for neutrophil granulocytopoiesis and its expression is severely reduced in congenital neutropenia
Julia Skokowa, Gunnar Cario, Murat Uenalan, Axel Schambach, Manuela Germeshausen, Karin Battmer, Cornelia Zeidler, Ulrich Lehmann, Matthias Eder, Christopher Baum, Rudolf Grosschedl, Martin Stanulla, Michaela Scherr & Karl Welte Nature Medicine12, 1191–1197
(2006); doi:10.1038/nm1484
| Summary | Full Text (HTML / PDF) |
letter Human C5aR knock-in mice facilitate the production and assessment of anti-inflammatory monoclonal antibodies
Hyun Lee, David Zahra, Alexis Vogelzang, Rebecca Newton, Jenny Thatcher, Annie Quan, Trina So, Jörg Zwirner, Frank Koentgen, Søren B Padkjær, Fabienne Mackay, Peter L Whitfeld & Charles R Mackay Nature Biotechnology24, 1279–1284
(2006); doi:10.1038/nbt1248
| Summary | Full Text (HTML / PDF) |
news and views Complementary therapies for inflammation
Yi Wang Nature Biotechnology24, 1224–1226
(2006); doi:10.1038/nbt1006-1224
| Summary | Full Text (HTML / PDF) |
review Immunological mechanisms of allergen-specific immunotherapy
Mark Larché , Cezmi A. Akdis and Rudolf Valenta Nature Reviews Immunology6, 761–771
(October 2006); doi:10.1038/nri1934
| Summary | Full Text (HTML / PDF) |
review Discovery and development of sorafenib: a multikinase inhibitor for treating cancer
Scott Wilhelm, Christopher Carter, Mark Lynch, Timothy Lowinger, Jacques Dumas, Roger A. Smith, Brian Schwartz, Ronit Simantov and Susan Kelley Nature Reviews Drug Discovery5, 835–844
(October 2006); doi:10.1038/nrd2130
| Summary | Full Text (HTML / PDF) |
September
review Model organisms: The mighty mouse: genetically engineered mouse models in cancer drug development
Norman E. Sharpless and Ronald A. DePinho Nature Reviews Drug Discovery7, 741–754
(September 2006); doi:10.1038/nrd2110
| Summary | Full Text (HTML / PDF) |
letter Topical drug rescue strategy and skin protection based on the role of Mc1r in UV-induced tanning
John A. D'Orazio, Tetsuji Nobuhisa, Rutao Cui, Michelle Arya, Malinda Spry, Kazumasa Wakamatsu, Vivien Igras, Takahiro Kunisada, Scott R. Granter, Emi K. Nishimura, Shosuke Ito and David E. Fisher Nature443, 340–344
(21 September 2006); doi:10.1038/nature05098
| Summary | Full Text (HTML / PDF) |
news and views TREKing toward new antidepressants
Joshua A Gordon & Rene Hen Nature Neuroscience9, 1081–1083
(2006); doi:10.1038/nn0906-1081
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article Crystal structures of a multidrug transporter reveal a functionally rotating mechanism
Satoshi Murakami , Ryosuke Nakashima, Eiki Yamashita, Takashi Matsumoto and Akihito Yamaguchi Nature443, 173–179
(14 September 2006); doi:10.1038/nature05076
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article Structure of a bacterial multidrug ABC transporter
Roger J. P. Dawson and Kaspar P. Locher Nature443, 180–185
(14 September 2006); doi:10.1038/nature05155
| Summary | Full Text (HTML / PDF) |
article The structure of H5N1 avian influenza neuraminidase suggests new opportunities for drug design
Rupert J. Russell, Lesley F. Haire, David J. Stevens, Patrick J. Collins, Yi Pu Lin, G. Michael Blackburn, Alan J. Hay, Steven J. Gamblin and John J. Skehel Nature443, 45–49
(7 September 2006); doi:10.1038/nature05114
| Summary | Full Text (HTML / PDF) |
news and views Structural biology: Antiviral drugs fit for a purpose
Ming Luo Nature443, 37–38
(7 September 2006); doi:10.1038/nature05003
| Full Text (HTML / PDF) |
August
news and views Eph tumour suppression: the dark side of Gleevec
Jean Y. J. Wang Nature Cell Biology8, 785–786
(10 August 2006); doi:10.1038/ncb0806-785
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review The biology of interleukin-2 and interleukin-15: implications for cancer therapy and vaccine design
Thomas A. Waldmann Nature Reviews Immunology6, 595–601
(August 2006); doi:10.1038/nri1901
| Summary | Full Text (HTML / PDF) |
review Targeting the mechanisms of tumoral immune tolerance with small-molecule inhibitors
Alexander J. Muller and Peggy A. Scherle Nature Reviews Cancer6, 613–625
(August 2006); doi:10.1038/nrc1929
| Summary | Full Text (HTML / PDF) |
July
article E2-EPF UCP targets pVHL for degradation and associates with tumor growth and metastasis
Cho-Rok Jung, Kyung-Sun Hwang, Jinsang Yoo, Won-Kyung Cho, Jin-Man Kim, Woo Ho Kim & Dong-Soo Im Nature Medicine12, 809–816
(July 2006); doi:10.1038/nm1440
| Summary | Full Text (HTML / PDF) |
review The role of nitric oxide in tumour progression
Dai Fukumura, Satoshi Kashiwagi and Rakesh K. Jain Nature Reviews Cancer6, 521–534
(July 2006); doi:10.1038/nrc1910
| Summary | Full Text (HTML / PDF) |
letter Suppression of vascular permeability and inflammation by targeting of the transcription factor c-Jun
Roger G Fahmy, Alla Waldman, Guishui Zhang, Ainslie Mitchell, Nicodemus Tedla, Hong Cai, Carolyn R Geczy, Colin N Chesterman, Michael Perry & Levon M Khachigian Nature Biotechnology24, 856–863
(July 2006); doi:10.1038/nbt1225
| Summary | Full Text (HTML / PDF) |
review Targeting signal transduction as a strategy to treat inflammatory diseases
Luke A. J. O'Neill Nature Reviews Drug Discovery7, 549–563
(July 2006); doi:10.1038/nrd2070
| Summary | Full Text (HTML / PDF) |
review Tumour microenvironment: TGFβ: the molecular Jekyll and Hyde of cancer
Brian Bierie and Harold L. Moses Nature Reviews Cancer6, 506–520
(July 2006); doi:10.1038/nrc1926
| Summary | Full Text (HTML / PDF) |
review The neurobiology of itch
Akihiko Ikoma, Martin Steinhoff, Sonja Ständer, Gil Yosipovitch and Martin Schmelz Nature Reviews Neuroscience7, 535–547
(25 June 2006); doi:10.1038/nrn1950
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June
review article Therapeutic potential of Toll-like receptor 9 activation
Arthur M. Krieg Nature Reviews Drug Discovery5, 471–484
(June 2006); doi:10.1038/nrd2059
| Summary | Full Text (HTML / PDF) |
brief communication Mutations in the gene encoding the PML nuclear body protein Sp110 are associated with immunodeficiency and hepatic veno-occlusive disease
Tony Roscioli, Simon T Cliffe, Donald B Bloch, Christopher G Bell, Glenda Mullan, Peter J Taylor, Maria Sarris, Joanne Wang, Jennifer A Donald, Edwin P Kirk, John B Ziegler, Ulrich Salzer, George B McDonald, Melanie Wong, Robert Lindeman & Michael F Buckley Nature Genetics38, 620–622
(June 2006); doi:10.1038/ng1780
| Summary | Full Text (HTML / PDF) |
May
letter Total insulin and IGF–I resistance in pancreatic β cells causes overt diabetes
Kohjiro Ueki, Terumasa Okada, Jiang Hu, Chong Wee Liew, Anke Assmann, Gabriella M Dahlgren, Jennifer L Peters, Jonathan G Shackman, Min Zhang, Isabella Artner, Leslie S Satin, Roland Stein, Martin Holzenberger, Robert T Kennedy, C Ronald Kahn & Rohit N Kulkarni Nature Genetics38, 583–588
(May 2006); doi:10.1038/ng1787
| Summary | Full Text (HTML / PDF) |
news and views Overcoming insulin resistance with CNTF
Rexford S Ahima Nature Medicine12, 511–512
(May 2006); doi:10.1038/nm0506–511
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review article MIF: a new cytokine link between rheumatoid arthritis and atherosclerosis
Eric F. Morand, Michelle Leech and Jürgen Bernhagen Nature Reviews Drug Discovery5, 399–411
(May 2006); doi:10.1038/nrd2029
| Summary | Full Text (HTML / PDF) |
article Bone morphogenetic protein signaling by hemojuvelin regulates hepcidin expression
Jodie L Babitt, Franklin W Huang, Diedra M Wrighting, Yin Xia, Yisrael Sidis, Tarek A Samad, Jason A Campagna, Raymond T Chung, Alan L Schneyer, Clifford J Woolf, Nancy C Andrews & Herbert Y Lin Nature Genetics38, 531–539
(May 2006) | doi:10.1038/ng1777
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news and views Iron metabolism meets signal transduction
Gregory J Anderson & David M Frazer Nature Genetics38, 503–503
(May 2006) | doi:10.1038/ng0506-503
| First Paragraph | Full Text (HTML / PDF) |
April
letter TMP21 is a presenilin complex component that modulates γ-secretase but not ε-secretase activity
Fusheng Chen, Hiroshi Hasegawa , Gerold Schmitt-Ulms, Toshitaka Kawarai, Christopher Bohm, Taiichi Katayama, Yongjun Gu, Nobuo Sanjo, Michael Glista, Ekaterina Rogaeva, Yosuke Wakutani, Raphaëlle Pardossi-Piquard, Xueying Ruan, Anurag Tandon, FrÈdéric Checler, Philippe Marambaud, Kirk Hansen, David Westaway, Peter St George-Hyslop and Paul Fraser Nature440, 1208–1212
(27 April 2006); doi:10.1038/nature04667
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review article Regulatory T cells, tumour immunity and immunotherapy
Weiping Zou Nature Reviews Immunology6, 295–307
(April 2006); doi:10.1038/nri1806
| Summary | Full Text (HTML / PDF) |
review article The therapeutic potential of monoamine oxidase inhibitors
Moussa B. H. Youdim, Dale Edmondson and Keith F. Tipton Nature Reviews Neuroscience7, 295–309
(April 2006); doi:10.1038/nrn1883
| Summary | Full Text (HTML / PDF) |
letter Pharmaco-metabonomic phenotyping and personalized drug treatment
T. Andrew Clayton, John C. Lindon, Olivier Cloarec, Henrik Antti, Claude Charuel, Gilles Hanton, Jean-Pierre Provost, Jean-LoÃL;c Le Net, David Baker, Rosalind J. Walley, Jeremy R. Everett and Jeremy K. Nicholson Nature440, 1073–1077
(20 April 2006); doi:10.1038/nature04648
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article Functional classification of drugs by properties of their pairwise interactions
Pamela Yeh, Ariane I Tschumi & Roy Kishony Nature Genetics38, 489–494
(April 2006); doi:10.1038/ng1755
| Summary | Full Text (HTML / PDF) |
review article Lipid II as a target for antibiotics
Eefjan Breukink and Ben de Kruijff Nature Reviews Drug Discovery5, 321–323
(April 2006); doi:10.1038/nrd2004
| Summary | Full Text (HTML / PDF) |
letter Role of matrix metalloproteinases in delayed cortical responses after stroke
Bing-Qiao Zhao, Sophia Wang, Hahn-Young Kim, Hannah Storrie, Bruce R Rosen, David J Mooney, Xiaoying Wang & Eng H Lo Nature Medicine12, 441–445
(April 2006); doi:10.1038/nm1387
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March
letter Anti-inflammatory actions of lipoxin A4 and aspirin-triggered lipoxin are SOCS-2 dependent
Fabiana S Machado, James E Johndrow, Lisia Esper, Alexandra Dias, Andre Bafica, Charles N Serhan & Julio Aliberti Nature Medicine12, 330–334
(March 2006); doi:10.1038/nm1355
| Summary | Full Text (HTML / PDF) |
review article Evolving knowledge and therapy of inflammatory bowel disease
Joshua R. Korzenik and Daniel K. Podolsky Nature Reviews Drug Discovery5, 197–209
(March 2006); doi:10.1038/nrd1986
| Summary | Full Text (HTML / PDF) |
review article Adenosine receptors as therapeutic targets
Kenneth A. Jacobson and Zhan-Guo Gao Nature Reviews Drug Discovery5, 247–264
(March 2006); doi:10.1038/nrd1983
| Summary | Full Text (HTML / PDF) |
article Robust Salmonella metabolism limits possibilities for new antimicrobials
Daniel Becker, Matthias Selbach, Claudia Rollenhagen, Matthias Ballmaier, Thomas F. Meyer, Matthias Mann and Dirk Bumann Nature440, 303–307
(16 March 2006); doi:10.1038/nature04616
| Summary | Full Text (HTML / PDF) |
review article Prions and their lethal journey to the brain
Neil A. Mabbott and G. Gordon MacPherson Nature Reviews Microbiology4, 201–211
(March 2006); doi:10.1038/nrmicro1346
| Summary | Full Text (HTML / PDF) |
review article An APRIL to remember: novel TNF ligands as therapeutic targets
Stacey R. Dillon, Jane A. Gross, Stephen M. Ansell and Anne J. Novak Nature Reviews Drug Discovery5, 235–246
(March 2006); doi:10.1038/nrd1982
| Summary | Full Text (HTML / PDF) |
letter Gout-associated uric acid crystals activate the NALP3 inflammasome
Fabio Martinon, Virginie Pétrilli, Annick Mayor, Aubry Tardivel and Jürg Tschopp Nature440, 237–241
(09 March 2006); doi:10.1038/nature04516
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review article Targeting multidrug resistance in cancer Nature Reviews Drug Discovery5, 219–234
(March 2006); doi:10.1038/nrd1984
| Summary | Full Text (HTML / PDF) |
news and views Plot against pot
Kerrie L Thomas Nature Medicine12, 281–283
(March 2006); doi:10.1038/nm0306-281
| Full Text (HTML/PDF) |
letter Mitoferrin is essential for erythroid iron assimilation
George C. Shaw, John J. Cope, Liangtao Li, Kenneth Corson, Candace Hersey, Gabriele E. Ackermann, Babette Gwynn, Amy J. Lambert, Rebecca A. Wingert, David Traver, Nikolaus S. Trede, Bruce A. Barut, Yi Zhou, Emmanuel Minet, Adriana Donovan, Alison Brownlie, Rena Balzan, Mitchell J. Weiss, Luanne L. Peters, Jerry Kaplan, Leonard I. Zon and Barry H. Paw Nature440, 96–100
(02 March 2006); doi:10.1038/nature04512
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article T cells use two directionally distinct pathways for cytokine secretion
Morgan Huse, Björn F Lillemeier, Michael S Kuhns, Daniel S Chen and Mark M Davis Nature Immunology7, 247–255
(March 2006); doi:10.1038/ni1304
| Abstract | Full Text (HTML/PDF) |
review article Antiviral antibody responses: the two extremes of a wide spectrum
Lars Hangartner, Rolf M. Zinkernagel and Hans Hengartner Nature Reviews Immunology6, 231–243
(March 2006); doi:10.1038/nri1783
| Summary | Full Text (HTML / PDF) |
February
review article Paradigm shift in neuroprotection by NMDA receptor blockade: Memantine and beyond
Stuart A. Lipton Nature Reviews Drug Discovery5, 160–170
(February 2006); doi:10.1038/nrd1958
| Summary | Full Text (HTML / PDF) |
news and views Crosscurrents in HIV-1 evolution
Joel N Blankson, Justin R Bailey and Robert F Siliciano Nature Immunology7, 121–122
(February 2006); doi:10.1038/ni0206-121
| Full Text (HTML/PDF) |
review article Antibody targeted drugs as cancer therapeutics
David Schrama, Ralph A. Reisfeld and Jürgen C. Becker Nature Reviews Drug Discovery5, 147–159
(February 2006); doi:10.1038/nrd1957
| Summary | Full Text (HTML / PDF) |
article Restoring function in exhausted CD8 T cells during chronic viral infection
Daniel L. Barber, E. John Wherry, David Masopust, Baogong Zhu, James P. Allison, Arlene H. Sharpe, Gordon J. Freeman and Rafi Ahmed Nature439, 682–687
(09 February 2006); doi:10.1038/nature04444
| Summary | Full Text (HTML / PDF) |
news and views Immunology: Exhausted T cells perk up
Matthew A. Williams and Michael J. Bevan Nature439, 669–670
(09 February 2006); doi:10.1038/439669a
| Full Text (HTML / PDF) |
letter Antiviral treatment is more effective than smallpox vaccination upon lethal monkeypox virus infection
Koert J. Stittelaar, Johan Neyts, Lieve Naesens, Geert van Amerongen, Rob F. van Lavieren, Antonin Holý, Erik De Clercq, Hubert G. M. Niesters, Edwin Fries, Chantal Maas, Paul G. H. Mulder, Ben A. M. van der Zeijst and Albert D. M. E. Osterhaus Nature439, 745–748
(09 February 2006); doi:10.1038/nature04295
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January
article TFE3 transcriptionally activates hepatic IRS-2, participates in insulin signaling and ameliorates diabetes
Yoshimi Nakagawa, Hitoshi Shimano, Tomohiro Yoshikawa, Tomohiro Ide, Mariko Tamura, Mika Furusawa, Takashi Yamamoto, Noriyuki Inoue, Takashi Matsuzaka, Akimitsu Takahashi, Alyssa H Hasty, Hiroaki Suzuki, Hirohito Sone, Hideo Toyoshima, Naoya Yahagi and Nobuhiro Yamada Nature Medicine12, 107–113
(January 2006); doi:10.1038/nm1334
| Abstract | Full Text (HTML/PDF) |
letter Oncogenic pathway signatures in human cancers as a guide to targeted therapies
Andrea H. Bild, Guang Yao, Jeffrey T. Chang, Quanli Wang, Anil Potti, Dawn Chasse, Mary-Beth Joshi, David Harpole, Johnathan M. Lancaster, Andrew Berchuck, John A. Olson Jr, Jeffrey R. Marks, Holly K. Dressman, Mike West and Joseph R. Nevins Nature439, 353–357
(February 2006); doi:10.1038/nature04296
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letter Hypoxia-inducible factor determines sensitivity to inhibitors of mTOR in kidney cancer
George V Thomas, Chris Tran, Ingo K Mellinghoff, Derek S Welsbie, Emily Chan, Barbara Fueger, Johannes Czernin and Charles L Sawyers Nature Medicine12, 122–127
(January 2006); doi:10.1038/nm1337
| First Paragraph | Full Text (HTML/PDF) |
letter A genetic strategy to treat sickle cell anemia by coregulating globin transgene expression and RNA interference
Selda Samakoglu, Leszek Lisowski, Tulin Budak-Alpdogan, Yelena Usachenko, Santina Acuto, Rosalba Di Marzo, Aurelio Maggio, Ping Zhu, John F. Tisdale, Isabelle Rivière and Michel Sadelain Nature Biotechnology24, 89–94
(January 2006); doi:10.1038/nbt1176
| First Paragraph | Full Text (HTML/PDF) |
review article Astrocyte-endothelial interactions at the blood-brain barrier
N. Joan Abbott, Lars Rönnbäck and Elisabeth Hansson Nature Reviews Neuroscience7, 41–53
(January 2006); doi:10.1038/nrn1824
| Summary | Full Text (HTML / PDF) |
review article COX isoforms in the cardiovascular system: understanding the activities of non-steroidal anti-inflammatory drugs
Jane A. Mitchell and Timothy D. Warner Nature Reviews Drug Discovery5, 75–86
(January 2006); doi:10.1038/nrd1929
| Summary | Full Text (HTML / PDF) |
letter An siRNA-based microbicide protects mice from lethal herpes simplex virus 2 infection
Deborah Palliser, Dipanjan Chowdhury, Qing-Yin Wang, Sandra J. Lee, Roderick T. Bronson, David M. Knipe and Judy Lieberman Nature439, 89–94
(05 January 2006); doi:10.1038/nature04263
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