signaling gateway home
registrationelectronic alerthelpcontact ussite guidesearch
cell signaling update signaling update home updates  news  research library featured articles conferences

Research library: Clinical / Drug discovery

2010: | February | January

Other Years: 2002 | 2003 | 2004 | 2005 | 2006 | 2007 | 2008 | 2009

review
Anti-virulence strategies to combat bacteria-mediated disease
David A. Rasko & Vanessa Sperandio
Nature Reviews Drug Discovery 9, 117–128
(February 2010); doi:10.1038/nrd3013
| Summary | Full Text (HTML / PDF) |

brief communication
In vivo selection of tumor-targeting RNA motifs
Jing Mi et al.
Nature Chemical Biology 6, 22–24
(January 2010); doi:10.1038/nchembio.277
| Summary | Full Text (HTML / PDF) |

review
Macrophage death and defective inflammation resolution in atherosclerosis
Ira Tabas
Nature Reviews Immunology 10, 36–46
(January 2010); doi:10.1038/nri2675
| Summary | Full Text (HTML / PDF) |

review
From pathogenesis to treatment of chronic lymphocytic leukaemia
Thorsten Zenz, Daniel Mertens, Ralf Küppers, Hartmut Döhner & Stephan Stilgenbauer
Nature Reviews Cancer 10, 37–50
(January 2010); doi:10.1038/nrc2764
| Summary | Full Text (HTML / PDF) |

letter
Somatic mutations of the Parkinson's disease–associated gene PARK2 in glioblastoma and other human malignancies
Selvaraju Veeriah et al.
Nature Genetics 42, 77–82
(January 2010); doi:10.1038/ng.491
| Summary | Full Text (HTML / PDF) |

review
Kinase mutations in human disease: interpreting genotype–phenotype relationships
Piya Lahiry, Ali Torkamani, Nicholas J. Schork & Robert A. Hegele
Nature Reviews Genetics 11, 60–74
(January 2010); doi:10.1038/nrg2707
| Summary | Full Text (HTML / PDF) |

review
The nuts and bolts of AGC protein kinases
Laura R. Pearce, David Komander & Dario R. Alessi
Nature Reviews Molecular Cell Biology 11, 9–22
(January 2010); doi:10.1038/nrm2822
| Summary | Full Text (HTML / PDF) |

review
Integrins in cancer: biological implications and therapeutic opportunities
Jay S. Desgrosellier & David A. Cheresh
Nature Reviews Cancer 10, 9–22
(January 2010); doi:10.1038/nrc2748
| Summary | Full Text (HTML / PDF) |

brief communication
A restricted spectrum of NRAS mutations causes Noonan syndrome
Ion C Cirstea et al.
Nature Genetics 42, 27–29
(January 2010); doi:10.1038/ng.497
| Summary | Full Text (HTML / PDF) |

letter
Novel mutant-selective EGFR kinase inhibitors against EGFR T790M
Wenjun Zhou et al.
Nature 462, 1070–1074
(24 December 2009); doi:10.1038/nature08622
| Full Text (HTML / PDF) |

article
Reduced histone deacetylase 7 activity restores function to misfolded CFTR in cystic fibrosis
Darren M Hutt et al.
Nature Chemical Biology 6, 25–33
(January 2010); doi:10.1038/nchembio.275
| Summary | Full Text (HTML / PDF) |

 Nature Publishing Group

HOME | SIGNALING UPDATE | MOLECULE PAGES | DATA CENTER | ABOUT US
registration | e-alert | help | contact us | site guide | search

© 2002-2009 Nature Publishing Group

Privacy Policy