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Research library: Development
2003: December | November | October | September | August | July | June | May | April | March | February | January
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article
Inositol- and folate-resistant neural tube defects in mice lacking the epithelial-specific factor Grhl-3
Stephen B Ting, Tomasz Wilanowski, Alana Auden, Mark Hall, Anne K Voss, Tim Thomas, Vishwas Parekh, John M Cunningham and Stephen M Jane
Nature Medicine 9, 1513–1519
(December 2003); doi:10.1038/nm961
| Abstract | Full Text (HTML/PDF) |
review article
Applying the principles of stem-cell biology to cancer
Ricardo Pardal, Michael F. Clarke and Sean J. Morrison
Nature Reviews Cancer 3, 895–902
(December 2003); doi:10.1038/nrc1232
| Abstract | Full Text (HTML / PDF) |
review article
Developmental genetics of the female reproductive tract in mammals
Akio Kobayashi and Richard R. Behringer
Nature Reviews Genetics 4, 969–980
(December 2003); doi:10.1038/nrg1225
| Abstract | Full Text (HTML / PDF) |
article
Mobility and cycling of synaptic protein-containing vesicles in axonal growth cone filopodia
Shasta L Sabo and A Kimberley McAllister
Nature Neuroscience 6, 1264–1269
(December 2003); doi:10.1038/nn1149
| Abstract | Full Text (HTML/PDF) |
news and views
A filopodial synapse?
Nature Cell Biology 5, 1047
(December 2003); doi:10.1038/ncb1203-1047
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news and views
Specifying motor neurons: up and down and back to front
William A Harris
Nature Neuroscience 6, 1247–1249
(December 2003); doi:10.1038/nn1203-1247
| Full Text (HTML/PDF) |
letters to nature
Development and maintenance of B and T lymphocytes requires antiapoptotic MCL-1
Joseph T. Opferman, Anthony Letai, Caroline Beard, Mia D. Sorcinelli, Christy C. Ong and Stanley J. Korsmeyer
Nature 426, 671–676
(11 December 2003); doi:10.1038/nature02067
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review article
Hedgehog signalling in cancer formation and maintenance
Marina Pasca di Magliano and Matthias Hebrok
Nature Reviews Cancer 3, 903–911
(December 2003); doi:10.1038/nrc1229
| Abstract | Full Text (HTML / PDF) |
article
Non-proliferative effects of lysophosphatidic acid enhance cortical growth and folding
Marcy A Kingsbury, Stevens K Rehen, James J A Contos, Christine M Higgins and Jerold Chun
Nature Neuroscience 6, 1292–1299
(December 2003); doi:10.1038/nn1157
| Abstract | Full Text (HTML/PDF) |
review article
Signalling mechanisms mediating neuronal responses to guidance cues
Kun-Liang Guan and Yi Rao
Nature Reviews Neuroscience 4, 941–956
(December 2003); doi:10.1038/nrn1254
| Abstract | Full Text (HTML / PDF) |
letters to nature
Delta-promoted filopodia mediate long-range lateral inhibition in Drosophila
Cyrille de Joussineau, Jonathan Soulé, Marianne Martin, Christelle Anguille, Philippe Montcourrier and Daniel Alexandre
Nature 426, 555–559
(04 December 2003); doi:10.1038/nature02157
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news and views
Developmental biology: Long-range signalling by touch
Stephen M. Cohen
Nature 426, 503–504
(04 December 2003); doi:10.1038/426503a
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article
Otx2 homeobox gene controls retinal photoreceptor cell fate and pineal gland development
Akihiro Nishida, Akiko Furukawa, Chieko Koike, Yasuo Tano, Shinichi Aizawa, Isao Matsuo and Takahisa Furukawa
Nature Neuroscience 6, 1255–1263
(December 2003); doi:10.1038/nn1155
| Abstract | Full Text (HTML/PDF) |
review article
The developmental role of serotonin: news from mouse molecular genetics
Patricia Gaspar, Olivier Cases and Luc Maroteaux
Nature Reviews Neuroscience 4, 1002–1012
(December 2003); doi:10.1038/nrn1256
| Abstract | Full Text (HTML / PDF) |
letters to nature
A positive-feedback-based bistable 'memory module' that governs a cell fate decision
Wen Xiong and James E. Ferrell Jr
Nature 426, 460–465
(27 November 2003); doi:10.1038/nature02089
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news and views
Cell biology: Thanks for the memory
Jill C. Sible
Nature 426, 392–393
(November 2003); doi:10.1038/426392a
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letters to nature
An ancient role for nuclear β-catenin in the evolution of axial polarity and germ layer segregation
Athula H. Wikramanayake, Melanie Hong, Patricia N. Lee, Kevin Pang, Christine A. Byrum, Joanna M. Bince, Ronghui Xu and Mark Q. Martindale
Nature 426, 446–450
(27 November 2003); doi:10.1038/nature02113
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letter
The large Maf factor Traffic Jam controls gonad morphogenesis in Drosophila
Michelle A. Li, Jeffrey D. Alls, Rita M. Avancini, Karen Koo and Dorothea Godt
Nature Cell Biology 5, 994–1000
(November 2003); doi:10.1038/ncb1058
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news and views
Stuck without Traffic Jam
Helen McNeill
Nature Cell Biology 5, 948–949
(November 2003); doi:10.1038/ncb1103-948
| Full Text (HTML/PDF) |
review article
The genetic and molecular basis of congenital eye defects
Jochen Graw
Nature Reviews Genetics 4, 876–888
(November 2003); doi:10.1038/nrg1202
| Abstract | Full Text (HTML / PDF) |
article
Vertebrate neurogenesis is counteracted by Sox1-3 activity
Magdalena Bylund, Elisabeth Andersson, Bennett G Novitch and Jonas Muhr
Nature Neuroscience 6, 1162–1168
(November 2003); doi:10.1038/nn1131
| Abstract | Full Text (HTML/PDF) |
news and views
Pulling the Soxs off proliferation
Kalyani Narasimhan
Nature Neuroscience 6, 1125
(November 2003); doi:10.1038/nn1103-1125
| Full Text (HTML/PDF) |
article
Eya protein phosphatase activity regulates Six1-Dach-Eya transcriptional effects in mammalian organogenesis
Xue Li, Kenneth A. Oghi, Jie Zhang, Anna Krones, Kevin T. Bush, Christopher K. Glass, Sanjay K. Nigam, Aneel K. Aggarwal, Richard Maas, David W. Rose and Michael G. Rosenfeld
Nature 426, 247–254
(20 November 2003); doi:10.1038/nature02083
| Abstract | Full Text (HTML / PDF) |
letters to nature
Eyes absent represents a class of protein tyrosine phosphatases
Jayanagendra P. Rayapureddi, Chandramohan Kattamuri, Brian D. Steinmetz, Benjamin J. Frankfort, Edwin J. Ostrin, Graeme Mardon and Rashmi S. Hegde
Nature 426, 295–298
(20 November 2003); doi:10.1038/nature02093
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letters to nature
The transcription factor Eyes absent is a protein tyrosine phosphatase
Tina L. Tootle , Serena J. Silver , Erin L. Davies , Victoria Newman, Robert R. Latek, Ishara A. Mills, Jeremy D. Selengut, Beth E. W. Parlikar and Ilaria Rebay
Nature 426, 299–302
(20 November 2003); doi:10.1038/nature02097
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news and views
Signal transduction: An eye on organ development
Jonathan A. Epstein and Benjamin G. Neel
Nature 426, 238–239
(20 November 2003); doi:10.1038/426238a
| Full Text (HTML / PDF) |
letters to nature
Testis determination requires insulin receptor family function in mice
Serge Nef , Sunita Verma-Kurvari, Jussi Merenmies, Jean-Dominique Vassalli, Argiris Efstratiadis, Domenico Accili and Luis F. Parada
Nature 426, 291–295
(20 November 2003); doi:10.1038/nature02059
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news and views
Developmental biology: Gender benders
Peter Koopman
Nature 426, 241
(20 November 2003); doi:10.1038/426241a
| Full Text (HTML / PDF) |
letter
Discs-Large and Strabismus are functionally linked to plasma membrane formation
Ok-Kyung Lee, Kristopher K. Frese, Jennifer S. James, Darshana Chadda, Zhi-Hong Chen, Ronald T. Javier and Kyung-Ok Cho
Nature Cell Biology 5, 987–993
(November 2003); doi:10.1038/ncb1055
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review article
Some assembly required: the development of neuronal synapses
Zheng Li and Morgan Sheng
Nature Reviews Molecular Cell Biology 4, 833–841
(November 2003); doi:10.1038/nrm1242
| Abstract | Full Text (HTML / PDF) |
letter
Interaction of reelin signaling and Lis1 in brain development
Amir H. Assadi, Guangcheng Zhang, Uwe Beffert, Robert S. McNeil, Amy L. Renfro, Sanyong Niu, Carlo C. Quattrocchi, Barbara A. Antalffy, Michael Sheldon, Dawna D. Armstrong, Anthony Wynshaw-Boris, Joachim Herz, Gabriella D'Arcangelo and Gary D. Clark
Nature Genetics 35, 270–276
(November 2003); doi:10.1038/ng1257
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letters to nature
Hedgehog signalling in the mouse requires intraflagellar transport proteins
Danwei Huangfu, Aimin Liu, Andrew S. Rakeman, Noel S. Murcia, Lee Niswander and Kathryn V. Anderson
Nature 426, 83–87
(06 November 2003); doi:10.1038/nature02061
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brief communication
Homologue disjunction in mouse oocytes requires proteolysis of securin and cyclin B1
Mary Herbert, Mark Levasseur, Hayden Homer, Katie Yallop, Alison Murdoch and Alex McDougall
Nature Cell Biology 5, 1023–1025
(November 2003); doi:10.1038/ncb1062
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article
A gene expression atlas of the central nervous system based on bacterial artificial chromosomes
Shiaoching Gong, Chen Zheng, Martin L. Doughty, Kasia Losos, Nicholas Didkovsky, Uta B. Schambra, Norma J. Nowak, Alexandra Joyner, Gabrielle Leblanc, Mary E. Hatten and Nathaniel Heintz
Nature 425, 917–925
(30 October 2003); doi:10.1038/nature02033
| Abstract | Full Text (HTML / PDF) |
news and views
Molecular neuroscience: BAC-to-BAC images of the brain
Huda Y. Zoghbi
Nature 425, 907–908
(30 October 2003); doi:10.1038/425907a
| Full Text (HTML / PDF) |
article
Motor neuron columnar fate imposed by sequential phases of Hox-c activity
Jeremy S. Dasen, Jeh-Ping Liu and Thomas M. Jessell
Nature 425, 926–933
(30 October 2003); doi:10.1038/nature02051
| Abstract | Full Text (HTML / PDF) |
letter
LKB1 (XEEK1) regulates Wnt signalling in vertebrate development
Olga Ossipova, Nabeel Bardeesy, Ronald A. DePinho and Jeremy B. A. Green
Nature Cell Biology 5, 889–894
(October 2003); doi:10.1038/ncb1048
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news and views
Wnt signalling gets XEEKy
Wilson K. Clements and David Kimelman
Nature Cell Biology 5, 861–863
(October 2003); doi:10.1038/ncb1003-861
| Full Text (HTML/PDF) |
letter
Epithelial tube morphogenesis during Drosophila tracheal development requires Piopio, a luminal ZP protein
Anna Jaz´win´ska, Carlos Ribeiro and Markus Affolter
Nature Cell Biology 5, 895–901
(October 2003); doi:10.1038/ncb1049
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review article
The genetic basis of mammalian neurulation
Andrew J. Copp, Nicholas D. E. Greene and Jennifer N. Murdoch
Nature Reviews Genetics 4, 784–793
(October 2003); doi:10.1038/nrg1181
| Abstract | Full Text (HTML / PDF) |
review article
Neural crest specification: migrating into genomics
Laura S. Gammill and Marianne Bronner-Fraser
Nature Reviews Neuroscience 4, 795–805
(October 2003); doi:10.1038/nrn1219
| Abstract | Full Text (HTML / PDF) |
review article
Cranial neural crest and the building of the vertebrate head
Fabio Santagati and Filippo M. Rijli
Nature Reviews Neuroscience 4, 806–818
(October 2003); doi:10.1038/nrn1221
| Abstract | Full Text (HTML / PDF) |
letters to nature
Widespread requirement for Hedgehog ligand stimulation in growth of digestive tract tumours
David M. Berman , Sunil S. Karhadkar , Anirban Maitra, Rocio Montes de Oca, Meg R. Gerstenblith, Kimberly Briggs, Antony R. Parker, Yutaka Shimada, James R. Eshleman, D. Neil Watkins and Philip A. Beachy
Nature 425, 846–851
(23 October 2003); doi:10.1038/nature01972
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letters to nature
Hedgehog is an early and late mediator of pancreatic cancer tumorigenesis
Sarah P. Thayer, Marina Pasca di Magliano, Patrick W. Heiser, Corinne M. Nielsen, Drucilla J. Roberts, Gregory Y. Lauwers, Yan Ping Qi, Stephan Gysin, Carlos Fernández-del Castillo, Vijay Yajnik, Bozena Antoniu, Martin McMahon, Andrew L. Warshaw and Matthias Hebrok
Nature 425, 851–856
(23 October 2003); doi:10.1038/nature02009
| First Paragraph | Full Text (HTML / PDF) |
news and views
Cancer: A twist in a hedgehog's tale
Matthew P. Scott
Nature 425, 780–782
(23 October 2003); doi:10.1038/425780a
| Full Text (HTML / PDF) |
letter
Stability and association of Smoothened, Costal2 and Fused with Cubitus interruptus are regulated by Hedgehog
Laurent Ruel, Ralph Rodriguez, Armel Gallet, Laurence Lavenant-Staccini and Pascal P. Thérond
Nature Cell Biology 5, 907–913
(October 2003); doi:10.1038/ncb1052
| Abstract | Full Text (HTML/PDF) |
letter
The Salvador partner Hippo promotes apoptosis and cell-cycle exit in Drosophila
Sophie Pantalacci, Nicolas Tapon and Pierre Léopold
Nature Cell Biology 5,921–927
(October 2003); doi:10.1038/ncb1051
| Abstract
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letter
Hippo promotes proliferation arrest and apoptosis in the Salvador/Warts pathway
Ryan S. Udan, Madhuri Kango-Singh, Riitta Nolo, Chunyao Tao and Georg Halder
Nature Cell Biology 5, 914–920
(October 2003); doi:10.1038/ncb1050
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news and views
Hippo and its mission for growth control
Hyung Don Ryoo and Hermann Steller
Nature Cell Biology 5, 853–855
(October 2003); doi:10.1038/ncb1003-853
| Full Text (HTML/PDF) |
review article
From developmental disorder to heritable cancer: it's all in the BMP/TGF-β family
Kristin A. Waite and Charis Eng
Nature Reviews Genetics 4, 763–773
(October 2003); doi:10.1038/nrg1178
| Abstract | Full Text (HTML / PDF) |
letters to nature
The Wnt/β-catenin pathway regulates cardiac valve formation
Adam F. L. Hurlstone, Anna-Pavlina G. Haramis, Erno Wienholds, Harry Begthel, Jeroen Korving, Fredericus van Eeden, Edwin Cuppen, Danica Zivkovic, Ronald H. A. Plasterk and Hans Clevers
Nature 425, 633–637
(09 October 2003); doi:10.1038/nature02028
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letters to nature
Jelly belly protein activates the receptor tyrosine kinase Alk to specify visceral muscle pioneers
Hsiu-Hsiang Lee, Audra Norris, Joseph B. Weiss and Manfred Frasch
Nature 425, 507–512
(02 October 2003); doi:10.1038/nature01916
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letters to nature
Jeb signals through the Alk receptor tyrosine kinase to drive visceral muscle fusion
Camilla Englund, Christina E. Lorén, Caroline Grabbe, Gaurav K. Varshney, Fabienne Deleuil, Bengt Hallberg and Ruth H. Palmer
Nature 425, 512–516
(02 October 2003); doi:10.1038/nature01950
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news and views
Developmental biology: Partners united
Matthew Freeman
Nature 425, 468–469
(02 October 2003); doi:10.1038/425468a
| Full Text (HTML / PDF) |
news and views
Developmental biology: Twisting the body into shape
Ian C. Scott and Didier Y. R. Stainier
Nature 425, 461–463
(02 October 2003); doi:10.1038/425461a
| Full Text (HTML / PDF) |
news and views
Cell biology: The hippo hypothesis
Michael E. Rothenberg and Yuh-Nung Jan
Nature 425, 469–470
(02 October 2003); doi:10.1038/425469a
| Full Text (HTML / PDF) |
article
Defective development and function of Bcl10-deficient follicular, marginal zone and B1 B cells
Liquan Xue, Stephan W Morris, Carlos Orihuela, Elaine Tuomanen, Xiaoli Cui, Renren Wen and Demin Wang
Nature Immunology 4, 857–865
(September 2003); doi:10.1038/ni963
| Abstract | Full Text (HTML/PDF) |
article
Lmx1b is essential for the development of serotonergic neurons
Yu-Qiang Ding, Ulrika Marklund, Wenlin Yuan, Jun Yin, Lauren Wegman, Johan Ericson, Evan Deneris, Randy L. Johnson and Zhou-Feng Chen
Nature Neuroscience 6, 933–938
(September 2003); doi:10.1038/nn1104
| Abstract | Full Text (HTML/PDF) |
article
TRPC5 is a regulator of hippocampal neurite length and growth cone morphology
Anna Greka, Betsy Navarro, Elena Oancea, Anne Duggan and David E. Clapham
Nature Neuroscience 6, 837–845
(August 2003); doi:10.1038/nn1092
| Abstract | Full Text (HTML/PDF) |
letters to nature
Complex between nidogen and laminin fragments reveals a paradigmatic β-propeller interface
Junichi Takagi , Yuting Yang , Jin-huan Liu, Jia-huai Wang and Timothy A. Springer
Nature 424, 969–974
(21 August 2003); doi:10.1038/nature01873
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article
Thymic stromal-derived lymphopoietin distinguishes fetal from adult B cell development
Christian A. J. Voßhenrich, Ana Cumano, Werner Müller, James P. Di Santo and Paulo Vieira
Nature Immunology 4, 773–779
(August 2003); doi:10.1038/ni956
| Abstract | Full Text (HTML/PDF) |
news and views
Getting a GPR on spindle asymmetry
S. Swaminathan
Nature Cell Biology 5, 692
(August 2003); doi:10.1038/ncb0803-692
| Full Text (HTML/PDF) |
letters to nature
Exclusion of germ plasm proteins from somatic lineages by cullin-dependent degradation
Cynthia DeRenzo, Kimberly J. Reese and Geraldine Seydoux
Nature 424, 685–689
(07 August 2003); doi:10.1038/nature01887
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article
Emx2 patterns the neocortex by regulating FGF positional signaling
Tomomi Fukuchi-Shimogori and Elizabeth A Grove
Nature Neuroscience 6, 825–831
(August 2003); doi:10.1038/nn1093
| Abstract | Full Text (HTML/PDF) |
scientific report
Fly and mammalian lipid phosphate phosphatase isoforms differ in activity both in vitro and in vivo
Camilla Burnett and Ken Howard
EMBO reports 4, 793–799
(August 2003); doi:10.1038/sj.embor.embor900
| Abstract | Full Text (HTML/PDF) |
news and views
Developmental biology: How to turn inside out
Rüdiger Schmitt and Manfred Sumper
Nature 424, 499–500
(31 July 2003); doi:10.1038/424499a
| Full Text (HTML / PDF) |
news and views
Neurobiology: Motor proteins branch out
Amanda Tromans
Nature 424, 503
(31 July 2003); doi:10.1038/424503a
| Full Text (HTML / PDF) |
news and views
Curling with kinesin
J. Horne
Nature Cell Biology 5, 696
(August 2003); doi:10.1038/ncb0803-696
| Full Text (HTML/PDF) |
letters to nature
The molecular nature of the zebrafish tail organizer
Antoine Agathon, Christine Thisse and Bernard Thisse
Nature 424, 448–452
(24 July 2003); doi:10.1038/nature01822
| First Paragraph | Full Text (HTML / PDF) |
news and views
Developmental biology: A tale of tails
Christof Niehrs
Nature 424, 375–376
(24 July 2003); doi:10.1038/424375a
| Full Text (HTML / PDF) |
news and views
Developmental biology: Boundary lines
Seth S. Blair
Nature 424, 379–381
(24 July 2003); doi:10.1038/424379a
| Full Text (HTML / PDF) |
letter
Hepatocyte nuclear factor 4α controls the development of a hepatic epithelium and liver morphogenesis
Fereshteh Parviz, Christine Matullo, Wendy D. Garrison, Laura Savatski, John W. Adamson, Gang Ning, Klaus H. Kaestner, Jennifer M. Rossi, Kenneth S. Zaret and Stephen A. Duncan
Nature Genetics 34, 292–296
(July 2003); doi:10.1038/ng1175
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letter
Gremlin is the BMP antagonist required for maintenance of Shh and Fgf signals during limb patterning
Mustafa K. Khokha, David Hsu, Lisa J. Brunet, Marc S. Dionne and Richard M. Harland
Nature Genetics 34, 303–307
(July 2003); doi:10.1038/ng1178
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review article
Looking back to the embryo: defining transcriptional networks in adult myogenesis
Maura H. Parker , Patrick Seale and Michael A. Rudnicki
Nature Reviews Genetics 4, 497–507
(July 2003); doi:10.1038/nrg1109
| Abstract | Full Text (HTML / PDF) |
review article
Half a century of neural prepatterning: the story of a few bristles and many genes
José Luis Gómez-Skarmeta, Sonsoles Campuzano and Juan Modolell
Nature Reviews Neuroscience 4, 587–598
(July 2003); doi:10.1038/nrn1142
| Summary | Full Text (HTML / PDF) |
news and views
Cell biology: The molecules that make muscle
Donald Gullberg
Nature 424, 138–140
(10 July 2003); doi:10.1038/424138a
| Full Text (HTML / PDF) |
letter
Accumulation of anchored proteins forms membrane diffusion barriers during neuronal polarization
Chieko Nakada, Kenneth Ritchie, Yuichi Oba, Mitsuhiro Nakamura, Yoko Hotta, Ryota Iino, Rinshi S. Kasai, Kazuhiko Yamaguchi, Takahiro Fujiwara and Akihiro Kusumi
Nature Cell Biology 5, 626–632
(July 2003); doi:10.1038/ncb1009
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news and views
Neuronal polarization: building fences for molecular segregation
Carlos G. Dotti and Mu-ming Poo
Nature Cell Biology 5, 591–594
(July 2003); doi:10.1038/ncb0703-591b
| Full Text (HTML/PDF) |
letter
Inhibition of caspase-9 through phosphorylation at Thr 125 by ERK MAPK
Lindsey A. Allan, Nick Morrice, Suzanne Brady, Gareth Magee, Shalini Pathak and Paul R. Clarke
Nature Cell Biology 5, 647–654
(July 2003); doi:10.1038/ncb1005
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review article
Calcium signalling during embryonic development
Sarah E. Webb and Andrew L. Miller
Nature Reviews Molecular Cell Biology 4, 539–551
(July 2003); doi:10.1038/nrm1149
| Summary | Full Text (HTML / PDF) |
article
Specification of dorsal telencephalic character by sequential Wnt and FGF signaling
Lena Gunhaga, Matthew Marklund, My Sjödal, Jen-Chih Hsieh, Thomas M Jessell and Thomas Edlund
Nature Neuroscience 6, 701–707
(July 2003); doi:10.1038/nn1068
| Abstract | Full Text (HTML/PDF) |
letter
BMP-7 counteracts TGF-β1-induced epithelial-to-mesenchymal transition and reverses chronic renal injury
Michael Zeisberg, Jun-ichi Hanai, Hikaru Sugimoto, Tadanori Mammoto, David Charytan, Frank Strutz and Raghu Kalluri
Nature Medicine 9, 964–968
(July 2003); doi:10.1038/nm888
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review article
Molecular regulation of vessel maturation
Rakesh K Jain
Nature Medicine 9, 685–693
(June 2003); doi:10.1038/nm0603-685
| Abstract | Full Text (HTML/PDF) |
letter
Trans allele methylation and paramutation-like effects in mice
Herry Herman, Michael Lu, Melly Anggraini, Aimee Sikora, Yanjie Chang, Bong June Yoon and Paul D Soloway
Nature Genetics 34, 199–202
(June 2003); doi:10.1038/ng1162
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letters to nature
Involvement of Notch and Delta genes in spider segmentation
Angelika Stollewerk, Michael Schoppmeier and Wim G. M. Damen
Nature 423, 863–865
(19 June 2003); doi:10.1038/nature01682
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letters to nature
Fibronectin requirement in branching morphogenesis
Takayoshi Sakai, Melinda Larsen and Kenneth M. Yamada
Nature 423, 876–881
(19 June 2003); doi:10.1038/nature01712
| First Paragraph | Full Text (HTML / PDF) |
review article
Endothelial signaling during development
Ondine Cleaver and Douglas A Melton
Nature Medicine 9, 661–668
(June 2003); doi:10.1038/nm0603-661
| Abstract | Full Text (HTML/PDF) |
review article
Reelin and brain development
Fadel Tissir and André M. Goffinet
Nature Reviews Neuroscience 4, 496–505
(June 2003); doi:10.1038/nrn1113
| Summary | Full Text (HTML / PDF) |
news and views
Manipulating hematopoietic stem cell amplification with Wnt
Connie J Eaves PhD
Nature Immunology 4, 511–512
(June 2003); doi:10.1038/ni0603-511
| Full Text (HTML/PDF) |
review article
Chemokine receptors: signposts to brain development and disease
Phuong B. Tran and Richard J. Miller
Nature Reviews Neuroscience 4, 444–455
(June 2003); doi:10.1038/nrn1116
| Summary | Full Text (HTML / PDF) |
article
MKP3 mediates the cellular response to FGF8 signalling in the vertebrate limb
Yasuhiko Kawakami, Joaquín Rodríguez-León, Christopher M. Koth, Dirk Büscher, Tohru Itoh, Ángel Raya, Jennifer K. Ng, Concepción Rodríguez Esteban, Shigeru Takahashi, Domingos Henrique, May-Fun Schwarz, Hiroshi Asahara and Juan Carlos Izpisúa Belmonte
Nature Cell Biology 5, 513–519
(June 2003); doi:10.1038/ncb989
| Abstract | Full Text (HTML/PDF) |
news and views
Deconstructing phosphatases in limb development
Andrew T. Dudley and Clifford J. Tabin
Nature Cell Biology 5, 499–501
(June 2003); doi:10.1038/ncb0603-499
| Full Text (HTML/PDF) |
review article
What does it take to make a natural killer?
Francesco Colucci, Michael A. Caligiuri and James P. Di Santo
Nature Reviews Immunology 3, 413–425
(May 2003); doi:10.1038/nri1088
| Summary | Full Text (HTML / PDF) |
article
A role for Wnt signalling in self-renewal of haematopoietic stem cells
Tannishtha Reya, Andrew W. Duncan, Laurie Ailles, Jos Domen, David C. Scherer, Karl Willert, Lindsay Hintz, Roel Nusse and Irving L. Weissman
Nature 423, 409–414
(22 May 2003); doi:10.1038/nature01593
| Abstract | Full Text (HTML / PDF) |
letters to nature
Wnt proteins are lipid-modified and can act as stem cell growth factors
Karl Willert, Jeffrey D. Brown, Esther Danenberg, Andrew W. Duncan, Irving L. Weissman, Tannishtha Reya, John R. Yates III and Roel Nusse
Nature 423, 448–452
(22 May 2003); doi:10.1038/nature01611
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letters to nature
Caenorhabditis elegans early embryogenesis and vulval morphogenesis require chondroitin biosynthesis
Ho-Yon Hwang, Sara K. Olson, Jeffrey D. Esko and H. Robert Horvitz
Nature 423, 439–443
(22 May 2003); doi:10.1038/nature01634
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letters to nature
Chondroitin proteoglycans are involved in cell division of Caenorhabditis elegans
Souhei Mizuguchi, Toru Uyama, Hiroshi Kitagawa, Kazuko H. Nomura , Katsufumi Dejima, Keiko Gengyo-Ando, Shohei Mitani, Kazuyuki Sugahara and Kazuya Nomura
Nature 423, 443–448
(22 May 2003); doi:10.1038/nature01635
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review
Deciphering skeletal patterning: clues from the limb
Francesca V. Mariani and Gail R. Martin
Nature 423, 319–325
(15 May 2003); doi:10.1038/nature01655
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review
Cranial skeletal biology
J. A. Helms and R. A. Schneider
Nature 423, 326–331
(15 May 2003); doi:10.1038/nature01656
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review
Developmental regulation of the growth plate
Henry M. Kronenberg
Nature 423, 332–336
(15 May 2003); doi:10.1038/nature01657
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review
Osteoclast differentiation and activation
William J. Boyle, W. Scott Simonet and David L. Lacey
Nature 423, 337–342
(15 May 2003); doi:10.1038/nature01658
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review
The genetic basis for skeletal diseases
Elazar Zelzer and Bjorn R. Olsen
Nature 423, 343–348
(15 May 2003); doi:10.1038/nature01659
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letter
Mammalian Sprouty4 suppresses Ras-independent ERK activation by binding to Raf1
Atsuo Sasaki, Takaharu Taketomi, Reiko Kato, Kazuko Saeki, Atsushi Nonami, Mika Sasaki, Masamitsu Kuriyama, Naoaki Saito, Masabumi Shibuya and Akihiko Yoshimura
Nature Cell Biology 5, 427–432
(May 2003); doi:10.1038/ncb978
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news and views
Split personalities: the agonistic antagonist Sprouty
Gerhard Christofori
Nature Cell Biology 5, 377–379
(May 2003); doi:10.1038/ncb0503-377
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article
Otx dose-dependent integrated control of antero-posterior and dorso-ventral patterning of midbrain
Eduardo Puelles, Dario Acampora, Emmanuel Lacroix, Massimo Signore, Alessandro Annino, Francesca Tuorto, Stefania Filosa, Giorgio Corte, Wolfgang Wurst, Siew-Lan Ang and Antonio Simeone
Nature Neuroscience 6, 453–460
(May 2003); doi:10.1038/nn1037
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letters to nature
Identification of Vangl2 and Scrb1 as planar polarity genes in mammals
Mireille Montcouquiol, Rivka A. Rachel, Pamela J. Lanford, Neal G. Copeland, Nancy A. Jenkins and Matthew W. Kelley
Nature 423, 173–177
(08 May 2003); doi:10.1038/nature01618
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news and views
Small changes in Wnt signalling
Sarah Greaves
Nature Cell Biology 5, 387
(May 2003); doi:10.1038/ncb0503-387
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letters to nature
Chibby, a nuclear β-catenin-associated antagonist of the Wnt/Wingless pathway
Ken-Ichi Takemaru, Shinji Yamaguchi, Young Sik Lee, Yang Zhang, Richard W. Carthew and Randall T. Moon
Nature 422, 905–909
(24 April 2003); doi:10.1038/nature01570
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review article
Genetics and the making of Homo sapiens
Sean B. Carroll
Nature 422, 849–857
(24 April 2003); doi:10.1038/nature01495
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review article
Polarized epithelial membrane traffic: conservation and plasticity
Keith Mostov, Tao Su and Martin ter Beest
Nature Cell Biology 5, 287–293
(April 2003); doi:10.1038/ncb0403-287
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article
Foxp3 programs the development and function of CD4+CD25+ regulatory T cells
Jason D. Fontenot, Marc A. Gavin and Alexander Y. Rudensky
Nature Immunology 4, 330–336
(April 2003); doi:10.1038/ni904
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article
An essential role for Scurfin in CD4+CD25+ T regulatory cells
Roli Khattri, Tom Cox, Sue-Ann Yasayko and Fred Ramsdell
Nature Immunology 4, 337–342
(April 2003); doi:10.1038/ni909
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news and views
Twenty-first century Foxp3
Anne O'Garra and Paulo Vieira
Nature Immunology 4, 304–306
(April 2003); doi:10.1038/ni0403-304
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review article
Cytokine control of memory T-cell development and survival
Kimberly S. Schluns and Leo Lefrançois
Nature Reviews Immunology 3, 269–279
(April 2003); doi:10.1038/nri1052
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letter
A defective response to Hedgehog signaling in disorders of cholesterol biosynthesis
Michael K. Cooper, Christopher A. Wassif, Patrycja A. Krakowiak, Jussi Taipale, Ruoyu Gong, Richard I. Kelley, Forbes D. Porter and Philip A. Beachy
Nature Genetics 33, 508–513
(April 2003); doi:10.1038/ng1134
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review article
Patterning cell types in the dorsal spinal cord: what the mouse mutants say
Tamara Caspary and Kathryn V. Anderson
Nature Reviews Neuroscience 4, 289–297
(April 2003); doi:10.1038/nrn1073
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article
Wnt-mediated axon guidance via the Drosophila Derailed receptor
Shingo Yoshikawa, Randall D. McKinnon, Michelle Kokel and John B. Thomas
Nature 422, 583–588
(10 April 2003); doi:10.1038/nature01522
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news and views
Developmental biology: How neurons avoid derailment
Paul A. Garrity
Nature 422, 570–571
(10 April 2003); doi:10.1038/422570a
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letters to nature
The BMP antagonist noggin regulates cranial suture fusion
Stephen M. Warren, Lisa J. Brunet, Richard M. Harland, Aris N. Economides and Michael T. Longaker
Nature 422, 625–629
(10 April 2003); doi:10.1038/nature01545
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perspectives
Wnts as morphogens? The view from the wing of Drosophila
Alfonso Martinez Arias
Nature Reviews Molecular Cell Biology 4, 321–325
(April 2003); doi:10.1038/nrm1078
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article
Transcriptional profiling identifies Id2 function in dendritic cell development
Christine Hacker, Ralf D. Kirsch, Xin-Sheng Ju, Thomas Hieronymus, Tatjana C. Gust, Christiane Kuhl, Thorsten Jorgas, Steffen M. Kurz, Stefan Rose-John, Yoshifumi Yokota and Martin Zenke
Nature Immunology 4, 380–386
(April 2003); doi:10.1038/ni903
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letter
Localized mutations in the gene encoding the cytoskeletal protein filamin A cause diverse malformations in humans
Stephen P. Robertson, Stephen R.F. Twigg, Andrew J. Sutherland-Smith, Valérie Biancalana, Robert J. Gorlin, Denise Horn, Susan J. Kenwrick, Chong A. Kim, Eva Morava, Ruth Newbury-Ecob, Karen H. Ørstavik, Oliver W.J. Quarrell, Charles E. Schwartz, Deborah J. Shears, Mohnish Suri, John Kendrick-Jones, C. Bacino, K. Becker, J. Clayton-Smith, M. Giovannucci-Uzielli, D. Goh, D. Grange, M. Krajewska-Welasek, D. Lacombe, C. Morris, S. Odent, R. Savarirayan, R. Stratton, A. Superti-Furga, A. Verloes, J. Vigneron, W. Wilcox, R. Winter, K. Young and Andrew O.M. Wilkie
Nature Genetics 33, 487–491
(April 2003); doi:10.1038/ng1119
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review article
Between genotype and phenotype: protein chaperones and evolvability
Suzanne L. Rutherford
Nature Reviews Genetics 4, 263–274
(April 2003); doi:10.1038/nrg1041
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review article
Neurotrophins and their receptors: A convergence point for many signalling pathways
Moses V. Chao
Nature Reviews Neuroscience 4, 299–309
(April 2003); doi:10.1038/nrn1078
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review article
Organogenesis of lymphoid tissues
Reina E. Mebius
Nature Reviews Immunology 3, 292–303
(April 2003); doi:10.1038/nri1054
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letters to nature
Hedgehog signalling within airway epithelial progenitors and in small-cell lung cancer
D. Neil Watkins, David M. Berman, Scott G. Burkholder, Baolin Wang, Philip A. Beachy and Stephen B. Baylin
Nature 422, 313–317
(20 March 2003); doi:10.1038/nature01493
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letters to nature
Links between signal transduction, transcription and adhesion in epithelial bud development
Colin Jamora, Ramanuj DasGupta, Pawel Kocieniewski and Elaine Fuchs
Nature 422, 317–322
(20 March 2003); doi:10.1038/nature01458
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news and views
Developmental biology: A hairy situation
Yann Barrandon
Nature 422, 272–273
(20 March 2003); doi:10.1038/422272a
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perspectives
Armadillo/β-catenin signals in the nucleus - proof beyond a reasonable doubt?
Mariann Bienz and Hans Clevers
Nature Cell Biology 5, 179–182
(March 2003); doi:10.1038/ncb0303-179
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article
Robo and Frazzled/DCC mediate dendritic guidance at the CNS midline
Marie-Pierre Furrer, Susan Kim, Brian Wolf and Akira Chiba
Nature Neuroscience 6, 223–230
(March 2003); doi:10.1038/nn1017
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article
The thrombomodulin-protein C system is essential for the maintenance of pregnancy
Berend Isermann, Rashmi Sood, Rafal Pawlinski, Mark Zogg, Shawn Kalloway, Jay L. Degen, Nigel Mackman and Hartmut Weiler
Nature Medicine 9, 331–337
(March 2003); doi:10.1038/nm825
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news and views
PAR1 signaling: more good than harm?
Wolfram Ruf
Nature Medicine 9, 258–260
(March 2003); doi:10.1038/nm0303-258
| Full Text (HTML/PDF) |
letters to nature
Extra-embryonic function of Rb is essential for embryonic development and viability
Lizhao Wu, Alain de Bruin, Harold I. Saavedra, Maja Starovic, Anthony Trimboli, Ying Yang, Jana Opavska, Pamela Wilson, John C. Thompson, Michael C. Ostrowski, Thomas J. Rosol, Laura A. Woollett, Michael Weinstein, James C. Cross, Michael L. Robinson and Gustavo Leone
Nature 421, 942–947
(27 February 2003); doi:10.1038/nature01417
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news and views
Developmental biology: A twist in a mouse tale
Nick Dyson
Nature 421, 903–904
(27 February 2003); doi:10.1038/421903a
| Full Text (HTML / PDF) |
news and views
Cell polarity: From embryo to axon
Melissa M. Rolls and Chris Q. Doe
Nature 421, 905–906
(27 February 2003); doi:10.1038/421905a
| Full Text (HTML / PDF) |
letter
Dlg, Scrib and Lgl regulate neuroblast cell size and mitotic spindle asymmetry
Roger Albertson and Chris Q. Doe
Nature Cell Biology 5, 166–170
(February 2003); doi:10.1038/ncb922
| First Paragraph | Full Text (HTML/PDF) |
review article
Wnts and TGFβ in synaptogenesis: old friends signalling at new places
Mary Packard, Dennis Mathew and Vivian Budnik
Nature Reviews Neuroscience 4, 113–120
(February 2003); doi:10.1038/nrn1036
| Summary | Full Text (HTML / PDF) |
article
LAB: A new membrane-associated adaptor molecule in B cell activation
Erin Janssen, Minghua Zhu, Weijia Zhang, Surapong Koonpaew and Weiguo Zhang
Nature Immunology 4, 117–123
(February 2003); doi:10.1038/ni882
| Abstract | Full Text (HTML/PDF) |
letters to nature
Fidelity in planar cell polarity signalling
Dali Ma, Chung-hui Yang, Helen McNeill, Michael A. Simon and Jeffrey D. Axelrod
Nature 421, 543–547
(30 January 2003); doi:10.1038/nature01366
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letters to nature
A role for Drosophila LKB1 in anterior-posterior axis formation and epithelial polarity
Sophie G. Martin and Daniel St Johnston
Nature 421, 379–384
(23 January 2003); doi:10.1038/nature01296
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article
Sonic hedgehog regulates adult neural progenitor proliferation in vitro and in vivo
Karen Lai, Brian K. Kaspar, Fred H. Gage and David V. Schaffer
Nature Neuroscience 6, 21–27
(January 2003); doi:10.1038/nn983
| Abstract | Full Text (HTML/PDF) |
letters to nature
Periodic Notch inhibition by Lunatic Fringe underlies the chick segmentation clock
J. K. Dale, M. Maroto, M.-L. Dequeant, P. Malapert, M. McGrew and O. Pourquie
Nature 421, 275–278
(16 January 2003); doi:10.1038/nature01244
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letters to nature
A zebrafish homologue of the chemokine receptor Cxcr4 is a germ-cell guidance receptor
Holger Knaut, Christian Werz, Robert Geisler, The Tübingen 2000 Screen Consortium and Christiane Nüsslein-Volhard
Nature 421, 279–282
(16 January 2003); doi:10.1038/nature01338
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news and views
Developmental biology: Germ-cell attraction
Prabhat S. Kunwar and Ruth Lehmann
Nature 421, 226–227
(16 January 2003); doi:10.1038/421226a
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article
Zinc finger protein too few controls the development of monoaminergic neurons
Gil Levkowitz, Jörg Zeller, Howard I. Sirotkin, Dorothy French, Sarah Schilbach, Hisashi Hashimoto, Masahiko Hibi, William S. Talbot and Arnon Rosenthal
Nature Neuroscience 6, 28–33
(January 2003); doi:10.1038/nn979
| Abstract | Full Text (HTML/PDF) |
article
Signalling and crosstalk of Rho GTPases in mediating axon guidance
Xiao-bing Yuan, Ming Jin, Xiaohua Xu, Yuan-quan Song, Chien-ping Wu, Mu-ming Poo and Shumin Duan
Nature Cell Biology 5, 38–45
(January 2003); doi:10.1038/ncb895
| Abstract | Full Text (HTML/PDF) |
letter
Interactions between the crumbs, lethal giant larvae and bazooka pathways in epithelial polarization
Guy Tanentzapf and Ulrich Tepass
Nature Cell Biology 5, 46–52
(January 2003); doi:10.1038/ncb896
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news and views
A genetic hierarchy controlling cell polarity
Kevin Johnson and Andreas Wodarz
Nature Cell Biology 5, 12–14
(January 2003); doi:10.1038/ncb0103-12
| Full Text (HTML/PDF) |
review article
Border-cell migration: The race is on
Denise J. Montell
Nature Reviews Molecular Cell Biology 4, 13–24
(January 2003); doi:10.1038/nrm1006
| Summary | Full Text (HTML / PDF) |
brief communication
A developmental switch in the signaling cascades for LTP induction
Hiroki Yasuda, Alison L. Barth, David Stellwagen and Robert C. Malenka
Nature Neuroscience 6, 15–16
(January 2003); doi:10.1038/nn985
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